KR20180062420A - Composition for eliminating hangover comprising fermented Allium hookeri as effective component - Google Patents

Abstract

The present invention relates to a composition comprising fermented Allium hookeri as an effective component, wherein the fermented Allium hookeri is effective in eliminating a hangover because the fermented Allium hookeri can reduce the content of ethanol and acetaldehyde increased by alcohol consumption by reducing the content of blood alcohol and enhancing the content of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). Therefore, the composition of the present invention can be usefully used as health functional food for eliminating the hangover, particularly as a beverage material for eliminating the hangover.

Description

Technical Field [0001] The present invention relates to a composition for fermented Allium hooker as effective component,

The present invention relates to a composition for hangover decoy comprising fermented trihydrate as an active ingredient.

Excessive drinking may temporarily cause hangover, headache, thirst, motion sickness, gastrointestinal disturbances, and diarrhea. In general, ethanol enters the body via the action of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) in the cytoplasm, and is excreted through the circulation system into the hepatocyte. Particularly, ethanol, which is an ethanol metabolite, Aldehydes are highly reactive and highly toxic and are known to be the major source of hangover and alcoholic side effects. Therefore, methods for dissolving hangover by promoting alcohol decomposition and acetaldehyde decomposition have been developed. Among them, methods using natural products are attracting attention. There are well-known natural products for relieving hangover, such as Chungja (Hovenia dulcis), Tongkung, Liquorice, Puerariae, Dermis, Maquinaceae, Kelp, Green tea, Plum and Doduck. Are manufactured and marketed. However, the effect is insignificant compared to excessive advertising, so there is still a demand for a more effective hangover drink for the market.

On the other hand, Allium hokeri is a plant that grows in the highlands of 1,400 ~ 4,200m above sea level. It is also known as a national vegetable in Myanmar. It is also called "三菜" because it has sweetness, bitter taste and spicy taste. It is also called 玄 菜. It was introduced in Korea in 2010, and successfully cultivated in 6 sites including Hadong, Jinju and Gyeongnam in 2011. In 2012, it was cultivated in Gimje, Gokchang, Sinan, Hadong, Jeju and Hacchon. Is cultivated in about 1,000 farms. It has been proven that it can be cultivated in Korea since the start of mass cultivation in 2012, and it is attracting attention as a new income crop in rural areas. It is a vegetable that is easily edible like Korean wave, onion, leek and garlic. It is used in various inflammatory diseases and cancer diseases by private prescription. It is rich in nitrogen and fiber as well as minerals such as calcium, iron, zinc, and manganese, and is rich in nitrogen and fiber, so that bone and tooth formation, blood production and blood circulation, energetic enhancement, body balance control, hypertension, arteriosclerosis, And has various effects such as promotion.

Korean Patent No. 1326413 discloses a composition for prevention of hangover, hangover and acetaldehyde-induced diseases, and Korean Patent No. 0442771 discloses a beverage having a hangover effect and a preparation method thereof. Korean Patent No. 1601947 discloses a hangover relief composition containing a peanut sprout extract and a preparation method thereof. However, the hangover detoxification composition containing the fermented triangle of the present invention as an active ingredient has not been disclosed.

The present invention has been made in view of the above-mentioned needs, and an object of the present invention is to provide a hangover detoxifying composition containing a fermented triangle as an active ingredient, and the fermented triangle reduces the blood alcohol content and the alcohol dehydrogenase (ADH) And that the content of aldehyde dehydrogenase (ALDH) is increased, thus completing the present invention.

In order to achieve the above object, the present invention provides a health functional food composition for hungry snails containing a fermented triangle as an active ingredient.

The present invention relates to a composition for hangover decoys containing fermented triangles as an active ingredient, wherein the fermented triangles reduce the blood alcohol content and reduce the content of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) Is effective in decreasing hangover by reducing acetaldehyde, which is an alcohol and alcohol decomposition intermediate, which is increased by alcohol ingestion. Therefore, it is very likely to be used as a health functional food for hangover, especially hangover and small-sized drinks.

The present invention relates to a health functional food composition for hangover marrow containing fermented trihydrate as an active ingredient. Preferably, the fermented triplex is fermented using a culture solution of a lactic acid bacteria and a fruit enzyme solution, but is not limited thereto.

In the present invention, the fermentation of the fermented triangle is preferably performed by adding the dried powder of the triple extract to the fermentation broth obtained by mixing the culture of the lactic acid bacteria and the fruit enzyme solution, and fermenting the fermented broth for 60 to 84 hours at a temperature of 30 to 40 ° C.

Preferred example of said lactic acid bacteria is Lactococcus Phedi o her CD rakti when (Pediococcus acidilactici), Lactobacillus aessi FIG filler's (Lactobacillus acidophilus MG501), Bifidobacterium ronggeom (Bifidobacterium longum MG723), Enterococcus passive help (Enterococcus faecium MG89) and Streptococcus thermophilus MG510. However, the present invention is not limited thereto.

The above-mentioned fruit enzyme solution is apple, audi, blueberry, omija, lemon, citron, tangerine, orange, grapefruit, kiwi. Pineapple, peach, grape, and plum, but it is not limited thereto. In some cases, it is also possible to substitute sugar as a nutrient without adding a fruit enzyme solution.

The hangover resolution means eliminating nausea, vomiting, abdominal pain, diarrhea, headache, thirst or gastrointestinal disorder, but it is not limited to this and can include general phenomena that occur after overeating. The fermented syrup can increase the content of alcohol dehydrogenase and aldehyde dehydrogenase in the blood.

The health functional food composition of the present invention may be prepared into any one form of powder, granule, ring, tablet, capsule, candy, syrup foamable beverage and beverage, preferably foamed beverage or beverage, It is not limited. The health functional food composition of the present invention is not particularly limited as long as it can be ingested to prevent or ameliorate hangover. When the health functional food composition of the present invention is used as a food additive, the health functional food composition may be added as it is, or may be used together with other food or food ingredients, and suitably used according to a conventional method. The active ingredient may be suitably used depending on its intended use (prevention or improvement). Generally, in the production of food or beverage, it is added in an amount of not more than 15 parts by weight, preferably not more than 10 parts by weight, based on the health functional food composition of the present invention. However, in the case of long-term intake for the purpose of controlling health, the amount may be less than the above range, and since there is no problem in terms of safety, the active ingredient may be used in an amount exceeding the above range. There is no particular limitation on the kind of the food. Examples of foods to which the health functional food composition can be added include meat products, sausages, breads, chocolate, candies, snacks, confectionery, pizza, ramen noodles, other noodles, gums, dairy products including ice cream, various soups, Alcoholic beverages, and vitamin complexes, all of which include health foods in a conventional sense. In addition, the health functional food composition of the present invention can be produced as a food, particularly a functional food. The functional food of the present invention includes components that are ordinarily added in food production, and includes, for example, proteins, carbohydrates, fats, nutrients, and seasonings. For example, when it is made of a drink, it may contain, in addition to the active ingredient, a natural carbohydrate or a flavoring agent as an additional ingredient. The natural carbohydrate may be selected from the group consisting of monosaccharides (e.g., glucose, fructose, etc.), disaccharides (e.g., maltose, sucrose etc.), oligosaccharides, polysaccharides (e.g., dextrin, cyclodextrin, , Xylitol, sorbitol, erythritol, etc.). The flavoring agent may be a natural flavoring agent (e.g., tau Martin, stevia extract, etc.) and a synthetic flavoring agent (e.g., saccharin, aspartame, etc.). In addition to the above-mentioned health functional food composition, it is possible to use various nutrients, vitamins, electrolytes, flavors, colorants, pectic acid and salts thereof, alginic acid and salts thereof, organic acids, protective colloid thickening agents, pH adjusting agents, stabilizers, preservatives, glycerin, A carbonating agent used in beverages, and the like.

Hereinafter, the present invention will be described in more detail with reference to Examples. It is to be understood by those skilled in the art that these embodiments are merely illustrative of the present invention and that the scope of the present invention is not limited thereto.

Example  One. Fermented  Produce

Samcheon was identified by morphological evaluation in direct farm of Golden Tree Co., Ltd. The roots of the triplex were washed with water and then lyophilized. The mixture was pulverized using a pulverizer, and a 20% 70% (v / v) fermentation alcohol was added to 100 g of the sample. The mixture was stirred twice at room temperature for 24 hours, Respectively.

The extract was filtered using ADVANTEC paper (No. 6), concentrated using a vacuum concentrator (EYELA N-1000, Riakikai Co., Ltd., Tokyo, Japan) and lyophilized.

In order to prepare the fermented triplex, the lyophilized product of the above-mentioned triplex extract was fermented for 60 to 84 hours in a medium containing Pediococcus acidilactici and apple enzyme solution at 33 to 37 ° C, Respectively.

Example  2. Fermentation Triptych  Ethanol in the blood by administration, alcohol dehydrogenase ( alcohol  dehydrogenase, ADH ) And Aldehyde  Dehydrogenase ( aldehyde dehydrogenase , ALDH )of box Confirmation of quantity change

Ethanol and the fermented trichomes of Example 1 were administered to male ICR mice at 7 weeks of age to confirm the hangover resolution effect of the fermented triangle of the present invention.

For the experiment, each mouse was divided into a negative control group without ethanol, ethanol and distilled water (control group), ethanol and fermented trifoliate group, and ethanol 4 g / kg with distilled water 10 ml / kg, Mg / kg < / RTI >

Serum ethanol, ADH, and ALDH contents were measured by using each assay kit after collecting 1 ml of blood from the orbital vein at 3 hours after ethanol and fermentation.

As a result, as shown in Table 1, the ethanol content of the blood increased with ethanol intake, and the amount of ADH and ALDH in the group fed with fermented trihydrate increased compared with the ethanol group. Therefore, it was confirmed that the consumption of the fermented trihydrate accelerated the metabolism of alcohol and had a hangover resolution effect.

Alcohol content
(Mg / dl) ADH
(Mg / dl) ALDH
(Mg / dl) Negative control group 1.60 0.31 103.26 + 4.51 0.14 + 0.02 Alcohol + distilled water 150.24 0.31 90.38 + - 5.51 0.34 ± 0.01 Alcohol + fermented tea 68.29 + - 3.71 116.26 ± 5.49 0.54 + 0.03

Claims (5)

The present invention relates to a health functional food composition useful as a hangover remedy comprising fermented trihydrate as an active ingredient. The health functional food composition according to claim 1, wherein the fermented trihydrate increases the content of alcohol dehydrogenase and aldehyde dehydrogenase in the blood. The method according to claim 1, wherein the fermented syrup is fermented at 30 to 40 DEG C for 60 to 84 hours by adding dry powder of a pan extract to a medium containing lactic acid bacteria and fruit enzyme solution, Composition. 4. The method according to claim 3, wherein the lactic acid bacterium is selected from the group consisting of Pediococcus acidilactici , Lactobacillus < RTI ID = 0.0 > acidophilus , Bifidobacterium longum), Enterococcus passive help (E nterococcus faecium) and Streptococcus Thermo filler's (Streptococcus thermophilus ). < / RTI > The health functional food composition of claim 1, wherein the composition is prepared from any one of powder, granule, ring, tablet, capsule, candy, syrup, foamable beverage and beverage.