KR20180058829A - Ezh2 억제제로 수모세포종을 치료하는 방법 - Google Patents
Ezh2 억제제로 수모세포종을 치료하는 방법 Download PDFInfo
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- KR20180058829A KR20180058829A KR1020187012552A KR20187012552A KR20180058829A KR 20180058829 A KR20180058829 A KR 20180058829A KR 1020187012552 A KR1020187012552 A KR 1020187012552A KR 20187012552 A KR20187012552 A KR 20187012552A KR 20180058829 A KR20180058829 A KR 20180058829A
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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| US201562238074P | 2015-10-06 | 2015-10-06 | |
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| US201662299312P | 2016-02-24 | 2016-02-24 | |
| US62/299,312 | 2016-02-24 | ||
| PCT/US2016/055554 WO2017062495A2 (en) | 2015-10-06 | 2016-10-05 | Method of treating medulloblastoma with an ezh2 inhibitor |
Publications (1)
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| KR20180058829A true KR20180058829A (ko) | 2018-06-01 |
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| EP (2) | EP3371175A4 (enExample) |
| JP (1) | JP7045985B2 (enExample) |
| KR (1) | KR20180058829A (enExample) |
| CN (1) | CN108699046A (enExample) |
| AU (3) | AU2016333982A1 (enExample) |
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| MX (1) | MX394355B (enExample) |
| SG (1) | SG10201909413SA (enExample) |
| WO (1) | WO2017062495A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230120883A (ko) | 2022-02-10 | 2023-08-17 | 서울대학교병원 | Hsp70을 표적으로 하는 수모세포종 치료 및 전이 억제 방법 |
Families Citing this family (11)
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| BR112015008447A2 (pt) | 2012-10-15 | 2017-07-04 | Epizyme Inc | métodos para tratar câncer |
| KR20180042356A (ko) | 2015-08-24 | 2018-04-25 | 에피자임, 인코포레이티드 | 암 치료 방법 |
| WO2017132518A1 (en) | 2016-01-29 | 2017-08-03 | Epizyme, Inc. | Combination therapy for treating cancer |
| JP7121660B2 (ja) | 2016-06-01 | 2022-08-18 | エピザイム，インコーポレイティド | 癌を処置するためのｅｚｈ２阻害剤の使用 |
| WO2017218953A1 (en) | 2016-06-17 | 2017-12-21 | Epizyme, Inc. | Ezh2 inhibitors for treating cancer |
| WO2018183885A1 (en) | 2017-03-31 | 2018-10-04 | Epizyme, Inc. | Combination therapy for treating cancer |
| AU2018275123A1 (en) | 2017-06-02 | 2020-01-30 | Epizyme, Inc. | Use of EZH2 inhibitors for treating cancer |
| MA49651A (fr) | 2017-07-19 | 2021-04-28 | Childrens Medical Center | Compositions et procédés pour traiter des maladies associées à un défaut d'empreinte |
| US11452727B2 (en) | 2017-09-05 | 2022-09-27 | Epizyme, Inc. | Combination therapy for treating cancer |
| US20220298510A1 (en) * | 2019-06-03 | 2022-09-22 | Icahn School Of Medicine At Mount Sinai | Compounds and methods for inhibiting cancers via rest inhibition |
| CN111905102A (zh) * | 2020-09-04 | 2020-11-10 | 福建医科大学附属第一医院 | Ezh2抑制剂在治疗胶质瘤中的应用 |
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| US4236945A (en) * | 1978-11-27 | 1980-12-02 | Allegheny Ludlum Steel Corporation | Phosphorus-iron powder and method of producing soft magnetic material therefrom |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| WO2011140325A1 (en) * | 2010-05-07 | 2011-11-10 | Glaxosmithkline Llc | Indazoles |
| SG185431A1 (en) | 2010-05-07 | 2012-12-28 | Glaxosmithkline Llc | Indoles |
| JO3438B1 (ar) | 2011-04-13 | 2019-10-20 | Epizyme Inc | مركبات بنزين مستبدلة بأريل أو أريل غير متجانس |
| EP2953941B1 (en) | 2013-02-11 | 2017-04-05 | Constellation Pharmaceuticals, Inc. | Modulators of methyl modifying enzymes, compositions and uses thereof |
| JP5989805B2 (ja) | 2012-02-10 | 2016-09-07 | コンステレーション・ファーマシューティカルズ・インコーポレイテッドＣｏｎｓｔｅｌｌａｔｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | メチル基変更酵素の調節物質、組成物及びその使用 |
| BR112015008447A2 (pt) * | 2012-10-15 | 2017-07-04 | Epizyme Inc | métodos para tratar câncer |
| KR102473113B1 (ko) * | 2013-12-06 | 2022-12-01 | 에피자임, 인코포레이티드 | 암 치료를 위한 병용 요법 |
| WO2017079757A1 (en) * | 2015-11-06 | 2017-05-11 | Epizyme, Inc. | Pediatric dosing for treatment of cancer with an ezh2 inhibitor |
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2016
- 2016-10-05 US US15/766,474 patent/US20190083504A1/en not_active Abandoned
- 2016-10-05 EP EP16854241.3A patent/EP3371175A4/en not_active Withdrawn
- 2016-10-05 WO PCT/US2016/055554 patent/WO2017062495A2/en not_active Ceased
- 2016-10-05 KR KR1020187012552A patent/KR20180058829A/ko not_active Ceased
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- 2016-10-05 MX MX2018004132A patent/MX394355B/es unknown
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- 2016-10-05 CA CA3000983A patent/CA3000983A1/en not_active Abandoned
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2018
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2020
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2021
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2023
- 2023-10-09 AU AU2023246384A patent/AU2023246384A1/en not_active Abandoned
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230120883A (ko) | 2022-02-10 | 2023-08-17 | 서울대학교병원 | Hsp70을 표적으로 하는 수모세포종 치료 및 전이 억제 방법 |
Also Published As
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| EP4309738A3 (en) | 2024-07-17 |
| MX394355B (es) | 2025-03-24 |
| EP4309738A2 (en) | 2024-01-24 |
| AU2016333982A1 (en) | 2018-04-26 |
| MX2018004132A (es) | 2018-09-26 |
| EP3371175A2 (en) | 2018-09-12 |
| EA201890878A1 (ru) | 2018-08-31 |
| JP2018529742A (ja) | 2018-10-11 |
| SG10201909413SA (en) | 2019-11-28 |
| CN108699046A (zh) | 2018-10-23 |
| AU2021204331A1 (en) | 2021-07-22 |
| IL258510A (en) | 2018-05-31 |
| US20200268765A1 (en) | 2020-08-27 |
| IL281318A (en) | 2021-04-29 |
| AU2023246384A1 (en) | 2023-11-02 |
| CA3000983A1 (en) | 2017-04-13 |
| JP7045985B2 (ja) | 2022-04-01 |
| EP3371175A4 (en) | 2019-09-25 |
| WO2017062495A2 (en) | 2017-04-13 |
| WO2017062495A3 (en) | 2017-06-08 |
| US20190083504A1 (en) | 2019-03-21 |
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