KR20180033801A - Oil-in-water emulsion type cosmetic composition comprising inorganic salt - Google Patents

Abstract

The present invention relates to an oil-in-water emulsion cosmetic composition comprising: a dual spheroid polymer amphipathic anisotropic powder having one side which is hydrophilic and the other side which is hydrophobic; and an inorganic salt, wherein the powder has a structure in which the hydrophobic side partially penetrates into the inside of the hydrophilic side to form a core of the hydrophilic side, and the hydrophilic side includes a functional group.

Description

[0001] The present invention relates to an oil-in-water cosmetic composition containing an inorganic salt,

The present invention relates to an underwater-type cosmetic composition containing an inorganic salt and a method for producing the same.

Formulation of emulsifying cosmetic composition can give moisture to skin with flexible feeling. The surfactant usually used for emulsification exhibits a dynamic emulsification state in which the emulsified particles circulate at the emulsified interface after emulsification.

An oil-in-water type emulsion formulation whose inner phase is an oil phase and a traumatic phase is a water phase is a formulation capable of imparting moisturizing power through the inner phase while showing a feeling of fresh feeling due to the characteristics of a traumatic aqueduct.

In the case of adding an inorganic salt that plays a role of imparting moisturizing or elasticity to the cosmetic composition, the inorganic salt added to the aqueous phase is contained in the emulsion particle in the case of a water-in-oil type, However, in case of underwater type, the inorganic salt included in the trauma affects the emulsion interface of the emulsion particle, which may seriously impair the emulsion stability.

The size and shape of the spherical fine particles made of the polymer are controlled according to the manufacturing method, and thus the application possibility is expanded. One of its applications is Pickering emulsion which can form stabilized macroporous particles using micro spherical particles. O / W emulsified particles are formed at a contact angle of 90 ° or more, and W / O emulsion particles are formed at a temperature of 90 ° or less depending on the degree of hydrophilicity / hydrophobicity of the spherical particles.

Attempts have been made to produce new anisotropic powders by imparting amphiphilic properties, both hydrophilic and hydrophobic, to the microspheres. An example is the Janus spherical particles. However, due to the morphological limitations of these spheres, there is a limit to the chemical anisotropy. In other words, although it is morphologically anisotropic, it is totally hydrophobic or hydrophilic, so that there is a limit to chemical anisotropy.

It has been attempted to produce anisotropic powders having surface activity by imparting chemical anisotropy together with geometric shape control. However, despite the advantage of its applicability of amphiphilic anisotropic powder, up to now, Has not been specifically developed, and there is a problem that it is difficult to mass-produce uniformly in the industry, so that no practical industrial application has been made.

The prior art of the present invention is disclosed in Korean Patent Publication No. 1997-0025588.

In view of the above, a problem to be solved by the present invention is to provide an underwater type emulsion cosmetic comprising an inorganic salt and excellent in emulsion stability.

In another aspect, a problem to be solved by the present invention is to provide a water-in-oil type emulsion cosmetic comprising a high content of inorganic salt and excellent emulsion stability.

In another aspect, a problem to be solved by the present invention is to provide an underwater type emulsifying cosmetic material having a light feeling.

In another aspect, a problem to be solved by the present invention is to provide an underwater type emulsion cosmetic composition having excellent moisture retention.

In another aspect, a problem to be solved by the present invention is to provide an underwater type emulsifying cosmetic which imparts elasticity to the skin.

From another viewpoint, a problem to be solved by the present invention is to provide an underwater type emulsifying cosmetic composition which can impart a flexible feeling and a pleasant feeling at the same time.

From another viewpoint, a problem to be solved by the present invention is to provide an underwater type emulsifying cosmetic composition which is excellent in moisture retention and can provide a cooling feeling.

In another aspect, a problem to be solved by the present invention is to provide a water-in-oil type emulsion cosmetic having a low viscosity and excellent stability.

Another aspect of the present invention is to provide an underwater type emulsion cosmetic comprising a high content of inorganic salt and excellent in high temperature stability.

In one aspect, the present invention provides a bi-sparoid-type polymeric amphipathic anisotropic powder comprising a hydrophilic one-side and a hydrophobic side; And an inorganic salt, wherein the water-

Wherein the powder has a structure in which the hydrophobic part partially penetrates into the inside of the hydrophilic one to form a hydrophilic core, and the hydrophilic one shell comprises a functional group.

In one aspect, the present invention can provide an underwater type emulsion cosmetic comprising an inorganic salt and excellent in emulsion stability.

From another point of view, the present invention can provide an underwater type emulsion cosmetic comprising a high content of inorganic salt and excellent emulsion stability.

In another aspect, the present invention can provide an underwater type emulsion cosmetic composition having a light feeling.

In another aspect, the present invention can provide an underwater type emulsified cosmetic composition having excellent moisture retention.

From another viewpoint, the present invention can provide an underwater type emulsion cosmetic which gives skin elasticity.

From another point of view, the present invention can provide an underwater type emulsified cosmetic composition capable of imparting a flexible feeling and a pleasant feeling at the same time.

From another point of view, the present invention can provide an underwater type emulsified cosmetic composition which is excellent in moisture retention and can provide a cooling feeling.

From another viewpoint, the present invention can provide an underwater type emulsified cosmetic composition having excellent flow stability at a low viscosity and excellent stability.

In another aspect, the present invention can provide an underwater type emulsion cosmetic comprising a high content of inorganic salt and excellent in high temperature stability.

1 is a schematic diagram for forming an amphiphilic anisotropic powder according to an embodiment of the present invention.
Fig. 2 is an optical microscope photograph showing emulsion particles observed immediately after preparation of the composition of Example 1 and after storage at 45 캜 for 2 weeks. Fig.
Fig. 3 is an optical microscope photograph showing emulsion particles observed immediately after preparation of the composition of Comparative Example 2 and after storage at 45 캜 for 2 weeks. Fig.

Embodiments of the present application will now be described in more detail with reference to the accompanying drawings. However, the techniques disclosed in the present application are not limited to the embodiments described herein but may be embodied in other forms. It should be understood, however, that the embodiments disclosed herein are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art. In the drawings, the widths and thicknesses of components are slightly enlarged in order to clearly illustrate each component. In addition, although only a part of the components is shown for convenience of explanation, those skilled in the art can easily grasp the rest of the components. It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit and scope of the invention.

As used herein, unless otherwise defined, at least one hydrogen atom of the functional groups of the invention is optionally substituted with at least one substituent selected from the group consisting of halogen (F, Cl, Br or I), a hydroxy group, a nitro group, an imino group A substituted or unsubstituted alkyl group having 1 to 20 carbon atoms, a substituted or unsubstituted heteroaryl group having 3 to 30 carbon atoms, a substituted or unsubstituted alkyl group having 1 to 20 carbon atoms, May be substituted with a substituted heterocycloalkyl group having 2-30 carbon atoms.

As used herein, "(meth) acrylic" may mean acryl and / or methacryl.

The particle size of the amphiphilic anisotropic powder herein is the maximum length measured as the longest length of the powder particle. The particle size range of the amphipathic powder herein means that at least 95% of the amphipathic anisotropic powder present in the composition falls within this range.

In the present specification, the average particle diameter of the emulsified particles means an average value of the diameter of the single particles. In the present specification, the mean particle size range of the emulsified particles means that at least 95% of the emulsified particles present in the composition fall within the above range.

According to one embodiment of the present invention, there is provided an underwater type emulsion cosmetic composition comprising an amphiphilic anisotropic powder and an inorganic salt.

In the present embodiment, the inorganic salt may impart a moisturizing and elastic effect to the composition. For example, sodium chloride, potassium chloride, lithium chloride, calcium chloride and magnesium chloride may be used.

The inorganic salt may be included in an amount of 0.0001% by weight to 5% by weight, for example, 0.5% by weight to 5% by weight based on the total weight of the composition. For example, the inorganic salt may be used in an amount of 0.0001 wt% or more, 0.001 wt% or more, 0.01 wt% or more, 0.05 wt% or more, 0.1 wt% or more, 0.2 wt% or more, 0.3 wt or more, More than 0.9%, more than 0.9%, more than 0.9%, more than 0.9%, more than 1.0%, more than 1.1%, more than 1.2% At least 1.6 wt.%, At least 1.7 wt.%, At least 1.8 wt.%, At least 1.9 wt.%, At least 2.0 wt.%, At least 2.1 wt.%, At least 2.2 wt.%, At least 2.3 wt.%, At least 2.4 wt. At least 2.6 wt%, at least 2.7 wt%, at least 2.8 wt%, at least 2.9 wt%, at least 3.0 wt%, at least 3.1 wt%, at least 3.2 wt%, at least 3.3 wt%, at least 3.4 wt% By weight, not less than 3.6% by weight, not less than 3.7% by weight, not less than 3.8% by weight or not less than 3.9% by weight, not more than 5.0% by weight, not more than 4.9% by weight, not more than 4.8% by weight, Up to 4.6 wt.%, Up to 4.5 wt.%, Up to 4.4 wt.%, Up to 4.3 wt.%, Up to 4.2 wt.%, Up to 4.1 wt.%, Up to 4.0 wt.%, Up to 3.9 wt. Up to 3.6 wt.%, Up to 3.4 wt.%, Up to 3.3 wt.%, Up to 3.2 wt.%, Up to 3.1 wt.%, Up to 3.0 wt.%, Up to 2.9 wt.%, Up to 2.8 wt. Or less, 2.6 wt% or less, 2.5 wt% or less, 2.4 wt% or less, 2.3 wt% or less, 2.2 wt% or less, 2.1 wt% or less, or 2.0 wt% or less. The composition according to the present embodiment can retain the emulsion stability of the composition while containing an inorganic salt in a high content of 0.5 wt% or more.

In the present embodiment, the amphiphilic anisotropic powder may be a double-sphere type polymeric amphipathic anisotropic powder consisting of a hydrophilic one-side and a hydrophobic one.

The powder may have a structure in which the hydrophobic other part partially penetrates into the inside of the hydrophilic one to form a hydrophilic one of the cores, and the hydrophilic one may include a functional group.

The powder may be in the form of a double sparoid, that is, a three-dimensional nephroid having a shape in which two spheroids are combined, and a symmetrical shape, asymmetric snowman snowman-shaped or asymmetric inverse snowman shape. The shape of the snowman means that the first and second polymer spheroids having different sizes are combined.

The spheroid may be, for example, a sphere, a globoid, or an oval shape, and may have a major axis length in microns or nanometers based on the longest length in the body cross-section. have.

In one embodiment, the hydrophilic one may be a core-shell structure in which the core is made of the same polymer as the hydrophobic base, and the hydrophilic one and the hydrophobic one may each take one spoloid shape of the double spoil. The binding portion between the two sphereoids of the double sphere may have a continuous structure from the hydrophilic core to the hydrophobic one.

In one embodiment, the hydrophilic one-side core and the hydrophobic one include a vinyl polymer, and the hydrophilic one-side shell may include a copolymer of a vinyl monomer and a monomer containing a functional group.

In one example, the vinyl polymer may be a vinyl aromatic polymer, and may be, for example, polystyrene.

In one example, the vinyl monomer may be vinyl aromatic. In one example, the vinyl monomer may be substituted or unsubstituted styrene.

In one example, the functional group may be a siloxane.

In one embodiment, the functional group-containing monomer may be a siloxane-containing (meth) acrylate, and specifically includes 3- (trimethoxysilyl) propyl acrylate, 3- (trimethoxysilyl) propyl methacrylate, vinyl Triethoxysilane, vinyltrimethoxysilane, or a mixture thereof.

In one embodiment, the hydrophilic one-side shell may further include a hydrophilic functional group.

For example, the hydrophilic functional group may be a functional group having a negative or positive charge or a polyethylene glycol (PEG) group, and may be a carboxylic acid group, a sulfonic group, a phosphate group, an amino group, an alkoxy group, an ester group, an acetate group, a polyethylene glycol group, And the like.

In one embodiment, the hydrophilic one-side shell may further include a sugar-containing functional group.

In one embodiment, the functional group containing the sugar is selected from the group consisting of N- {N- (3-triethoxysilylpropyl) aminoethyl} gluconamide, N- (3-triethoxysilylpropyl) - (3-triethoxysilylpropyl) aminoethyl} -oligo-hyaluronamide, and the like.

In one embodiment, the amphiphilic anisotropic powder may have a particle size of 100 to 1500 nm. For example, the amphiphilic anisotropic powder may have a particle size of 100 to 500 nm, or 200 to 300 nm. Specifically, the amphiphilic anisotropic powder preferably has a particle size of 100 nm or more, 200 nm or more, 300 nm or more, 400 nm or more, 500 nm or more, 600 nm or more, 700 nm or more, 800 nm or more, 900 nm or more, 1200 nm or more, 1200 nm or more, 1300 nm or more or 1400 nm or more and 1500 nm or less, 1400 nm or less, 1300 nm or less, 1200 nm or less, 1100 nm or less, 1000 nm or less, 900 nm or less and 800 nm or less , 700 nm or less, 600 nm or less, 500 nm or less, 400 nm or less, 300 nm or less, or 200 nm or less.

In one example, the amphiphilic anisotropic powder may form macro emulsion particles of 1 to 100 mu m. In another aspect, the amphiphilic anisotropic powder may be a large emulsion particle of 5 to 100 mu m, 10 to 100 mu m, 10 to 50 mu m, or 25 mu m. Specifically, the amphiphilic anisotropic powder may have an amphiphilic anisotropic powder of 1 탆 or more, 2 탆 or more, 3 탆 or more, 4 탆 or more, 5 탆 or more, 6 탆 or more, 7 탆 or more, 8 탆 or more, 9 탆 or more, Not more than 100 占 퐉, not more than 90 占 퐉, not more than 80 占 퐉, not more than 70 占 퐉, not more than 60 占 퐉, not more than 50 占 퐉, not less than 50 占 퐉, not less than 80 占 퐉, not less than 50 占 퐉, not less than 20 占 퐉, not less than 20 占 퐉, not less than 25 占 퐉, Mu] m or less, 40 [micro] m or less, 30 [micro] m or less, 25 or less, 20 or less, 15 or less, 10 or less or 5 or less.

The hydrophobic portion and the hydrophilic portion of the amphipathic anisotropic powder have different orientations toward the interface, whereby the macro emulsion particles can be formed. The above-described macro emulsified particles can provide an emulsified formulation having a low viscosity having a soft feel.

While the interface film formed by a general molecular level surfactant forms a dynamic emulsification state, the emulsion particle formed by the amphiphilic anisotropic powder increases the thickness of the interfacial film to several hundreds nm and forms a solid interfacial film . Through the formation of the interfacial film, the stability of emulsification is improved and a stable emulsified state can be maintained without being affected by the inorganic salt.

In one embodiment, the composition comprises the amphiphilic anisotropic powder in an amount of, for example, at least 0.1%, at least 0.2%, at least 0.3%, at least 0.4%, at least 0.5%, at least 0.6% , Not less than 0.7 wt%, not less than 0.8 wt%, not less than 0.9 wt%, or not less than 1.0 wt%, not more than 20 wt%, not more than 19 wt%, not more than 18 wt%, not more than 17 wt% 14% or less, 13% or less, 12% or less, 11% or less, 10% or less, 9% or less, 8% or less, 7% or less, 6% % Or less, 4 wt% or less, or 3 wt% or less. For example, the composition may comprise from 0.1% to 20% by weight, for example from 1% to 3%, of the amphipathic anisotropic powder relative to the total weight of the composition. Stable emulsion particles can be formed within the above range, and emulsion particles having an appropriate size can be formed.

In one embodiment, the composition comprises inorganic salts and amphiphilic anisotropic powders in a weight ratio of inorganic salt: amphiphilic anisotropic powder of 1: 9 to 9: 1, such as 1: 9 to 5: 1, such as 2.0: As shown in FIG. Within this range, a stable emulsified state can be maintained without being affected by inorganic salts.

The method for producing a cosmetic composition according to an embodiment of the present invention may include preparing the amphiphilic anisotropic powder and emulsifying the oil phase and the water phase using the amphoteric anisotropic powder produced.

In one embodiment of the present invention, the amphiphilic anisotropic powder includes a hydrophilic one (first polymer spoloid) and a hydrophobic other (second polymer spoloid), the hydrophilic one having a core-shell structure, the hydrophobic one And at least partially penetrating into the inside of the hydrophilic one to form a hydrophilic one of the cores, wherein the one hydrophilic shell comprises a functional group.

In one embodiment of the present invention, the amphiphilic anisotropic powder may be prepared by polymerizing a first monomer to prepare a core of a first polymer spoloid, coating the core of the first polymer spoloid to form a core- And preparing an amphiphilic anisotropic powder in which the second polymer spolide is formed by reacting the first polymer spolide of the core-shell structure with the first monomer.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a schematic view showing the principle of formation of an amphiphilic anisotropic powder according to an embodiment of the present invention. FIG. The core of the first polymer spolide is formed through the shell of the first polymer spolide by the above-mentioned manufacturing method, and is grown to form the second polymer spoloid.

In one embodiment, the amphiphilic anisotropic powder is prepared by (1) stirring the first monomer and the polymerization initiator to prepare a core of the first polymer spolide; (2) stirring the prepared core of the first polymer spolide with a monomer containing a first monomer, a polymerization initiator and a functional group to prepare a first polymer spolide having a coated core-shell structure; (3) preparing an amphiphilic anisotropic powder in which the second polymer spolide is formed by stirring the first polymer spoloid of the prepared core-shell structure with the second monomer and the polymerization initiator.

In the above steps (1), (2) and (3), stirring may be rotary stirring. It is preferable to rotate and stir because chemical mechanical modification and homogeneous mechanical mixing are required for producing uniform particles. The rotational stirring may be performed in a cylindrical rotating reactor, but the rotational stirring method is not limited thereto.

At this time, the design inside the reactor has a great influence on powder formation. The size and location of the baffles in the cylindrical rotating reactor and the degree of spacing between the impeller and the baffles greatly influence the uniformity of the particles produced. It is desirable to minimize the interval between the blades of the inner wing and the impeller to equalize the convection flow and the strength thereof, and to feed the powder reaction liquid below the wing length and to maintain the impeller rotation speed at a high speed. 200 rpm, and the length to diameter ratio of the reactor may be 1 to 3: 1 to 5, more specifically 10 to 30 cm in diameter and 10 to 50 cm in height. The reactor size can be varied in proportion to the reaction capacity. The material of the cylindrical rotating reactor may be ceramics, glass, etc., and the temperature at the time of stirring is preferably 50 to 90 ° C.

In the cylindrical rotating reactor, the simple rotation method is capable of producing uniform particles, and is a low energy method requiring less energy and maximizing the reaction efficiency, enabling mass production. The conventional tumbling method in which the reactor itself rotates requires high energy and restricts the size of the reactor since the entire reactor must be tilted at a constant angle and rotated at high speed. The amount produced due to reactor size limitations was also limited to small quantities of the order of several hundreds of milligrams to several grams, making them unsuitable for mass production.

In one embodiment, the core of the first polymer spolide and the second polymer spolide include a vinyl polymer, and the shell of the first polymer spolide may include a copolymer of a vinyl monomer and a monomer containing a functional group.

In one example, the vinyl polymer may be a vinyl aromatic polymer, and may be, for example, polystyrene.

In one embodiment, the first monomer and the second monomer may be the same or different, and may be specifically vinyl monomers. The first monomer added in the step (2) is the same as the first monomer used in the step (1), and the polymerization initiator used in each step may be the same or different.

In one example, the vinyl monomer may be vinyl aromatic. In one example, the vinyl monomer may be substituted or unsubstituted styrene.

In one example, the polymerization initiator may be a radical polymerization initiator, specifically, a peroxide type, an azo type, or a mixture thereof. Ammonium persulfate, sodium persulfate and potassium persulfate may also be used.

In one example, in the step (1), the first monomer and the polymerization initiator may be mixed at a weight ratio of 100 to 1000: 1. In another aspect, the first monomer and the polymerization initiator may be mixed in a weight ratio of 100 to 750: 1, or 100 to 500: 1, or 100 to 250: 1.

In another aspect, a stabilizer may be added together with the first monomer and the polymerization initiator in the step (1) to mix the first monomer, the polymerization initiator, and the stabilizer in a weight ratio of 100 to 1000: 1: 0.001 to 5. The powder size and shape are determined according to the first polymer spoil size adjustment in the initial stage (1), and the first polymer spoil size can be adjusted according to the weight ratio of the first monomer, the polymerization initiator, and the stabilizer. In addition, by mixing at the weight ratio within the above range, there is an effect that the uniformity of the anisotropic powder can be increased.

In one example, the stabilizer may be an ionic vinyl monomer, and specifically sodium 4-vinylbenzene sulfonate may be used. Stabilizers prevent swelling of the resulting particles and provide positive or negative charge on the powder surface to electrostatically prevent interactions (bonds) during grain formation.

The weight ratio of the first monomer, the polymerization initiator and the stabilizer is 110 to 130: 1: 1 to 5, specifically 115 to 125: 1: 2 to 4, when the amphiphilic anisotropic powder has a size of 200 to 250 nm. 1 < / RTI > polymer spolide.

When the amphiphilic anisotropic powder has a size of 400 to 450 nm, the weight ratio of the first monomer, the polymerization initiator and the stabilizer is in the range of 225 to 240: 1: 1 to 3, specifically 230 to 235: 1: 1 to 3 , ≪ / RTI > the first polymeric spheroids.

When the amphiphilic anisotropic powder has a size of 1100 to 2500 nm, the first polymer having a weight ratio of the first monomer, the polymerization initiator and the stabilizer is 110 to 130: 1: 0, specifically 115 to 125: 1: 0 ≪ / RTI >

The amphiphilic anisotropic powder having an asymmetric snowman shape is preferably an amorphous powder having a weight ratio of the first monomer, the polymerization initiator and the stabilizer of 100 to 140: 1: 8 to 12, specifically 110 to 130: 1: 9 to 11 Can be prepared from polymeric sphereoids.

The amphiphilic anisotropic powder having an asymmetric reverse snowman shape is preferably an amorphous powder having a weight ratio of the first monomer, the polymerization initiator and the stabilizer of 100: 1 to 140: 1: 1 to 5: 1, specifically 110: 130: 1: 1 < / RTI > polymer spolide.

In one embodiment, the monomer containing a functional group in the step (2) may be a siloxane-containing (meth) acrylate. Specific examples thereof include 3- (trimethoxysilyl) propyl acrylate, 3- (trimethoxysilyl) Methacrylate, vinyltriethoxysilane, vinyltrimethoxysilane, or a mixture thereof.

In one embodiment, the monomer containing the first monomer, the polymerization initiator and the functional group in the step (2) may be mixed at a weight ratio of 80 to 98: 0.2 to 1.0: 1 to 20. In another aspect, the first monomer, the polymerization initiator, and the monomer containing the functional group may be mixed at a weight ratio of 160 to 200: 1: 6 to 40. The degree of coating can be controlled according to the weight ratio, and the shape of the amphipathic anisotropic powder is determined according to the degree of coating, and when the weight ratio is adjusted, the coating thickness is increased to about 10 to 30%, specifically about 20% And the coating is too thick, so that the pulverization does not proceed or the pulverization is proceeded well without the problem that the pulverization is too thin. In addition, by mixing at the weight ratio within the above range, there is an effect that the uniformity of the anisotropic powder can be increased.

According to the above step (3), a part of the core of the first polymer spolide is protruded from the one side of the first polymer spolide of the core-shell structure through the shell and the protrusions are grown by the polymer of the second monomer, Can be formed.

For example, in the step (3), the second monomer and the polymerization initiator may be mixed in a weight ratio of 150 to 250: 1. In another aspect, the second monomer and the polymerization initiator may be present in an amount of from 160 to 250: 1, or from 170 to 250: 1, or from 180 to 250: 1, or from 190 to 250: 1, or from 200 to 250: : 1, or 220 to 250: 1, or 230 to 250: 1, or 240 to 250: 1.

In another aspect, the second monomer, the polymerization initiator and the stabilizer may be mixed in a weight ratio of 150: 250: 1: 0.001 to 5 by adding the second monomer and the polymerization initiator together with the stabilizer in the step (3). Specific types of stabilizers are as described above. By mixing at a weight ratio within the above range, uniformity of the anisotropic powder can be enhanced.

In one embodiment, in the step (3), the second monomer content may be 40 to 300 parts by weight when the weight of the first polymer spoil of the core-shell structure is 100 parts by weight. Specifically, when the second monomer content is 40 to 100 parts by weight when the first polymer spoil weight of the core-shell structure is 100 parts by weight, the asymmetric snowman type powder is obtained, and 100 to 150 parts by weight, or 110 to 150 parts by weight, When the weight is in the range of 150 to 300 parts by weight or in the range of 160 to 300 parts by weight, an asymmetric reverse snowman type powder is obtained. In addition, by mixing at the weight ratio within the above range, there is an effect that the uniformity of the anisotropic powder can be increased.

In another embodiment of the present invention, in the production of an amphiphilic anisotropic powder according to an embodiment of the present invention, the step (3) may further include the step of (4) introducing a hydrophilic functional group into the produced anisotropic powder have.

In one embodiment, the hydrophilic functional group in step (4) is not limited thereto, but may be introduced using a silane coupling agent and a reaction control agent.

In one embodiment, the silane coupling agent is selected from the group consisting of (3-aminopropyl) trimethoxysilane, N- [3- (trimethoxysilyl) propyl] ethylenediamine, N- [3- (trimethoxysilyl) (Trimethoxysilyl) propyl] urea and 3 - [(trimethoxysilyl) propyloxy] -1,2 (trimethylsilyl) Propanediol, and specifically may be at least one selected from the group consisting of N- [3- (trimethoxysilyl) propyl] ethylenediamine.

For example, the silane coupling agent may be added in an amount of 35 to 65 parts by weight, for example, 40 to 60 parts by weight based on 100 parts by weight of the anisotropic powder prepared in the step (3). Within this range, hydrophilization can be appropriately performed.

In one example, the reaction modifier may be ammonium hydroxide.

For example, the reaction modifier may be added in an amount of 85 to 115 parts by weight, for example, 90 to 110 parts by weight based on 100 parts by weight of the anisotropic powder prepared in the step (3). Within this range, hydrophilization can be appropriately performed.

In another embodiment of the present invention, in the production of the amphiphilic anisotropic powder according to one embodiment of the present invention, the step (3) is followed by (4) a step of introducing a sugar-containing functional group into the produced anisotropic powder .

In the step (4), the functional group containing sugar is not limited thereto, but may be introduced using a sugar-containing silane coupling agent and a reaction control agent.

According to one exemplary embodiment, the sugar-containing silane coupling agent is selected from the group consisting of N- {N- (3-triethoxysilylpropyl) aminoethyl} gluconamide, N- (3-triethoxysilylpropyl) And N- {N- (3-triethoxysilylpropyl) aminoethyl} -oligo-hyaluronamide.

According to one exemplary embodiment, the reaction modifier may be ammonium hydroxide.

For example, the reaction modifier may be added in an amount of 85 to 115 parts by weight, for example, 90 to 110 parts by weight based on 100 parts by weight of the anisotropic powder prepared in the step (3). The introduction of a sugar-containing functional group within the above range can be suitably performed.

The preparation of the amphiphilic anisotropic powder according to the above method does not use a cross-linking agent, so there is no production entanglement. Thus, the yield is high and uniform, and mass production is easier than the tumbling method using a simple agitation method. Particularly, there is an advantage that a nano-sized powder having a size of 300 nm or less can be mass-produced in a uniform range of size from several tens of g to several tens of kg.

The composition according to this embodiment may have a viscosity of greater than or equal to about 1000 cps, greater than about 1200 cps, greater than about 1300 cps, greater than about 1400 cps, greater than about 1500 cps, greater than about 1600 cps, greater than about 1700 cps, Or more, at least 1900 cps, at least 2000 cps, at least 2100 cps, at least 2200 cps, at least 2300 cps, at least 2400 cps, or at least 2500 cps, and no more than 20,000 cps, no more than 19,000 cps, no more than 18,000 cps, no more than 17,000 cps, no more than 16,000 cps Less than 15000 cps, less than 14000 cps, less than 13000 cps, less than 12000 cps, less than 11000 cps, less than 10,000 cps, less than 8900 cps, less than 8800 cps, less than 8700 cps, less than 8600 cps, less than 8500 cps, less than 8400 cps, 8,300 cps or less, 8,800 cps or less, 8000 cps or less, 7900 cps or less, 7800 cps or less, 7700 cps or less, 7600 cps or less, 7500 cps or less, 7400 cps or less, 7300 cps or less, 7200 cps or less, 7100 cps Less than 7000 cps, less than 6900 cps, less than 6800 cps, less than 6700 cps, less than 6600 cps, less than 6500 cps, less than 6400 cps Less than or equal to 6300 cps, less than or equal to 6200 cps, less than or equal to 6100 cps, or less than or equal to 6000 cps. For example, the viscosity may be 1,000 to 20,000 cps, 1,000 to 15,000 cps, and 3,000 cps to 5,000 cps.

The composition according to this embodiment can provide the above wide range of viscosity because it can maintain the stability of emulsified formulations without increasing the viscosity by using an excess amount of thickener even when the inorganic salt is contained in a high content . For example, 10,000 cps or less, 5,000 cps or less, or 3,000 cps or less, for example, 1,000 cps to 10,000 cps, 1,000 cps to 8,000 cps, or 1,000 cps to 5,000 cps, even when the inorganic salt is contained in a high content. It is possible to prepare a composition of the present invention. A flowable flexible formulation can be provided within the above range, so that a fresh feeling without feeling of tackiness can be exhibited.

Since the composition according to the present embodiment can form a stable emulsified formulation without containing an excessive amount of aggrecan or an excessive amount of surfactant, the feeling of use is not deteriorated or the skin irritation is not caused by the thickener or the surfactant, It is possible to provide an excellent composition.

The composition according to this embodiment can provide an emulsified composition including an inorganic salt to provide a moisturizing power. The composition according to this embodiment can provide an emulsified composition that can provide skin elasticity by including an inorganic salt.

The composition according to this embodiment can form emulsified formulations having a robust emulsion interface that can not be achieved with conventional surfactants, including amphiphilic anisotropic powders. Therefore, it is possible to provide an underwater type emulsion composition which is not disturbed by the emulsified interface due to the high content of inorganic salts present in the traumatic aqua regime, has excellent emulsion stability, and is excellent in high temperature and long time stability.

The composition according to the present embodiment is excellent in emulsion stability in an oil-in-water type emulsion even though it contains an inorganic salt, and can exhibit a pleasant feel without feeling of tackiness as an emulsified composition, while at the same time giving an advantageous effect due to an inorganic salt. In particular, stability is not affected even in the presence of a high content of inorganic salt, and the above-mentioned effect can be exhibited.

The composition according to this embodiment may exhibit aging emulsion stability over a wide temperature range, and the temperature may be, for example, from -10 ° C to 60 ° C.

The composition according to this embodiment can contain a large emulsion particle to provide a soft and soft feel.

The composition according to the present embodiment can be formulated into various formulations such as lotion, emulsion, cream and the like.

The cosmetic composition according to embodiments of the present invention may be formulated containing a cosmetically or dermatologically acceptable medium or base. It may be in the form of a suspension, a microemulsion, a microcapsule, a microgranule or an ionic (liposome) and a non-ionic follicular dispersion, or a cream, a skin, a lotion, a powder, an ointment, a spray, May be provided in the form of a stick. It can also be used in the form of a foam or in the form of an aerosol composition further containing a compressed propellant. These compositions may be prepared according to conventional methods in the art.

In addition, the cosmetic composition according to embodiments of the present invention may be in the form of powders, fatty substances, organic solvents, solubilizers, thickeners, gelling agents, softeners, antioxidants, suspending agents, stabilizers, foaming agents, , Water, ionic or nonionic emulsifiers, fillers, sequestering agents, chelating agents, preservatives, vitamins, barrier agents, wetting agents, essential oils, dyes, pigments, hydrophilic or lipophilic active agents, lipid vesicles or cosmetics And any other ingredients used, such as cosmetics or adjuvants commonly used in the field of dermatology. Such adjuvants are introduced in amounts commonly used in the cosmetics or dermatological fields. The cosmetic composition according to the embodiments of the present invention may further contain a skin absorption promoting substance to increase the skin improving effect.

Hereinafter, the present invention will be described in more detail with reference to Examples. It is to be understood by those skilled in the art that these embodiments are merely illustrative of the present invention and that the scope of the present invention is not construed as being limited by these embodiments.

 [Production Examples 1 to 4]

Production Examples 1 to 4 were prepared according to the compositions shown in Table 1 below. Specific methods are described below.

The components used in the following Production Examples are as follows.

1L Reactor standard composition ratio (g) - Average powder size 250 nm PS
(1L shaking type reaction tank) CS DB Water 300 PS 300 CS 240 MeOH 40 Water 250 Water 350 Styrene 50 TMSPA 6 AIBN 0.2 KPS 0.5 Styrene 50 Styrene 40 SVBS 1.0 AIBN 0.2 SVBS 0.35

MeOH: Methanol cosolvent

KPS: Potassium persulfate (initiator)

SVBS: Sodium vinyl benzene sulfonate (stabilizer)

PS: Polystyrene (polymer bead)

CS: Coated first polymeric spheroid with core-shell structure

DB: Anisotropic powder

TMSPA: Trimethoxysilyl propylacrylate (functional group)

AIBN: Azobisisobutyronitrile (polymerization initiator)

Manufacturing example  1. Polystyrene (PS) First polymer Speroid  Produce

50 g of styrene as a monomer, 1.0 g of sodium 4-vinylbenzenesulfonate as a stabilizer and 0.5 g of azobisisobutyronitrile (AIBN) as a polymerization initiator were mixed in a water bath at 75 DEG C For 8 hours. The reaction was stirred in a cylindrical rotating reactor. The cylindrical rotating reactor was 11 cm in diameter, 17 cm in height, made of glass, and rotated at a speed of 200 rpm.

Manufacturing example  2. Manufacture of Coated First Polymer Spheroid with Core-Shell (CS) Structure

(Styrene), 6 g of TMSPA (3- (trimethoxysilyl) propylacrylate) as a monomer, and 0.2 g of azobisisobutyronitrile (AIBN) as a polymerization initiator were added to 300 g of the obtained first polymeric spolide of polystyrene ) Were mixed and reacted at 75 DEG C for 8 hours. The reaction was stirred in a cylindrical rotating reactor.

Manufacturing example  3. Amphipathic  Anisotropy Powder  (DB) manufacturing

40 g of styrene as a monomer, 0.35 g of sodium 4-vinylbenzenesulfonate as a stabilizer, and 0.35 g of azobisisobutyronitrile as a polymerization initiator were added to 240 g of the polystyrene core shell (PS-CS) water dispersion solution obtained as a result of the reaction, And 0.2 g of azobisisobutyronitrile (AIBN) were mixed and heated at 75 캜 for 8 hours. The reaction was stirred in a cylindrical rotating reactor to produce an amphiphilic anisotropic powder.

Manufacturing example  4. Hydrophilized Amphipathic  Anisotropy Powder  Produce

30 g of N- [3- (trimethoxysilyl) propyl] ethylenediamine as a silane coupling agent and 30 g of N- [3- (trimethoxysilyl) propyl] ethylenediamine were added to 600 g of the aqueous dispersion solution of the obtained anisotropic powder, (Ammmonium hydroxide) were mixed and reacted at 25 DEG C for 24 hours to introduce a hydrophilic functional group. The reaction was stirred in a cylindrical rotating reactor to prepare a hydrophilized amphipathic anisotropic powder.

[ Example 1 and Comparative Examples 1 and 2] Preparation of an emulsion composition for underwater type

The underwater type emulsion compositions of Example 1 and Comparative Examples 1 and 2 were prepared according to the composition shown in Table 2 below. Example 1 is an emulsified composition prepared using the amphiphilic anisotropic powder produced according to Production Example 3, and Comparative Examples 1 and 2 are emulsion compositions using a general surfactant.

Raw material name Example 1 Comparative Example 1 Comparative Example 2 D.I.WATER Water solvent To 100 To 100 To 100 Aqueous dispersion amphiphilic anisotropic powder 10 0 0 Phenoxetol Phenoxyethanol antiseptic 0.3 0.3 0.3 Sensiva 50 Ethylhexylglycerin antiseptic 0.05 0.05 0.05 Fermandiol Propanediol Moisturizer 6 6 6 Keltrol CG-SFT Xanthan gum Incrementer 0.1 0.1 0.1 Dracorin CE GLYCERYL STEARATE CITRATE Surfactants 0 One One Puresyn 4 HYDROGENATED C6-14 OLEFIN POLYMERS Emollient 10 10 10 Sepiplus 400 WATER * POLYACRYLATE-13 * POLYISOBUTENE * POLYSORBATE 20 * SORBITAN ISOSTEARATE Incrementer 0.3 0.3 0 Sepimax Zen WATER * POLYACRYLATE CROSSPOLYMER-6 * T-BUTYL ALCOHOL Incrementer One One One Salt salt Conditioning agent 2.45 2.45 2.45

* Water-dispersed ampholytic anisotropic powder: A solution prepared by dissolving 10% by weight of the amphiphilic anisotropic powder of Preparation Example 3 in 55% by weight of purified water and 35% by weight of butylene glycol

[ Test Example  1] Evaluation of viscosity with time

After maintaining the composition according to Example 1 and Comparative Examples 1 and 2 at 30 ° C. for 2 weeks, the viscosity change of the composition with time was measured using a viscometer (LVDV-II + PRO, BROOKFIELD, USA) Are shown in Table 3.

(Unit: cps) Example 1 Comparative Example 1 Comparative Example 2 Immediately after manufacture 1789 12148 6449 1 week 1809 14328 5449 2 weeks 1859 15948 4299

From the results of Table 3, it can be seen that in Example 1, a low viscosity formulation is formed and a constant viscosity is maintained over 2 weeks, whereas in Comparative Example 1, a high viscosity formulation is formed and a viscosity change is shown. In Comparative Example 2, The formulation is formed, but it can be seen that the width of viscosity change is very large with time.

[ Test Example 2] Evaluation of formulation stability according to time and temperature

The formulation stability of the compositions according to Example 1 and Comparative Examples 1 and 2 was observed at 45 ° C for 2 weeks and the results are shown in Table 4 below.

High temperature stability
( 45`C  2 weeks) Example 1 Comparative Example 1 Comparative Example 2 Whether creaming stability stability Creaming Whether the oil is separated stability Oil separation Oil separation

In the results of Table 4, in Comparative Example 1 using a general surfactant, creaming phenomenon was not observed because it was a high-viscosity formulation after being maintained at 45 ° C for two weeks. However, it was confirmed that the oil was separated to show a layered structure, , It can be confirmed that the creaming phenomenon occurs, the oil is separated, the formulation is unstable, and the emulsified state can not be maintained. On the other hand, the composition of Example 1 does not exhibit creaming or oil separation phenomenon even when maintained at a high temperature for a long period of time, and shows no discoloration or irregularity, and thus it can be confirmed that the emulsion formulation is stable.

[ Test Example 3] Evaluation of emulsion particle stability

The compositions according to Example 1 and Comparative Example 2 were maintained at 45 캜 for 2 weeks, and emulsion particles were observed under an optical microscope immediately after and two weeks after the preparation, and the change with time was confirmed. The results are shown in FIG. 2 and FIG.

From the results shown in Fig. 2, it can be seen that the emulsion particle formed immediately after preparation of the composition of Example 1 stably remains at 45 占 폚 for 2 weeks without significant fluctuation. On the other hand, in the result of FIG. 3, it can be seen that in the case of Comparative Example 2, small emulsion particles formed at the beginning formed large particles and collapsed to emulsify the emulsion state.

Claims (18)

A double spheroidal polymeric amphipathic anisotropic powder consisting of a hydrophilic one-side and a hydrophobic one; And an inorganic salt, wherein the water-
Wherein the powder partially penetrates into the inside of the hydrophilic one to form a hydrophilic one of the cores, and the hydrophilic one of the shells comprises a functional group. The method according to claim 1,
Wherein the inorganic salt is included in an amount of 0.5% by weight or more based on the total weight of the composition. The method according to claim 1,
Wherein the inorganic salt is comprised between 0.5% and 5% by weight based on the total weight of the composition. The method according to claim 1,
Wherein the inorganic salt is at least one selected from the group consisting of sodium chloride, potassium chloride, lithium chloride, calcium chloride, and magnesium chloride. The method according to claim 1,
Wherein the composition comprises from 0.1% to 20% by weight of the powder based on the total weight of the composition. The method according to claim 1,
Wherein the composition has a viscosity of from 1000 cps to 20000 cps. The method according to claim 1,
Wherein the functional group is a siloxane. The method according to claim 1,
The hydrophilic one side of the powder is a core-shell structure,
Wherein the hydrophilic one-side core and the hydrophobic one include a vinyl polymer,
The hydrophilic one-side shell may comprise a vinyl monomer; And a monomer containing a functional group. 9. The method of claim 8,
Wherein the vinyl polymer is a vinyl aromatic polymer. 9. The method of claim 8,
Wherein the vinyl polymer is a vinyl aromatic monomer. 9. The method of claim 8,
Wherein the functional group-containing monomer is a vinyl polymer wherein the vinyl polymer is a siloxane-containing (meth) acrylate. The method according to claim 1,
The powder has a shape in which two spheroids are bonded,
An asymmetric snowman shape or an asymmetric inverted snowman shape with respect to said joined portion. The method according to claim 1,
Wherein the powder has a particle size of from 100 to 1500 nm. The method according to claim 1,
Wherein the amphiphilic anisotropic powder forms macro emulsion particles having an average particle size of from 1 to 100 mu m. The method according to claim 1,
Wherein the hydrophilic one-side shell is further introduced with a hydrophilic functional group. 16. The method of claim 15,
Wherein the hydrophilic functional group is at least one selected from the group consisting of a carboxylic acid group, a sulfonic group, a phosphate group, an amino group, an alkoxy group, an ester group, an acetate group, a polyethylene glycol group and a hydroxyl group. The method according to claim 1,
Wherein the hydrophilic one-side shell is further introduced with a sugar-containing functional group. 18. The method of claim 17,
The functional groups containing the sugar include N- {N- (3-triethoxysilylpropyl) aminoethyl} gluconamide, N- (3-triethoxysilylpropyl) -Triethoxysilylpropyl) aminoethyl} -oligo-hyaluronamide. ≪ / RTI >

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