KR20180030092A - 핵산을 사용하여 검색 가능한 정보를 저장하는 방법 - Google Patents

핵산을 사용하여 검색 가능한 정보를 저장하는 방법 Download PDF

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KR20180030092A
KR20180030092A KR1020187003839A KR20187003839A KR20180030092A KR 20180030092 A KR20180030092 A KR 20180030092A KR 1020187003839 A KR1020187003839 A KR 1020187003839A KR 20187003839 A KR20187003839 A KR 20187003839A KR 20180030092 A KR20180030092 A KR 20180030092A
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sequence
bit
monomer
nucleic acid
oligonucleotide
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조지 엠. 처치
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프레지던트 앤드 펠로우즈 오브 하바드 칼리지
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KR1020187003839A 2015-07-13 2016-07-13 핵산을 사용하여 검색 가능한 정보를 저장하는 방법 Withdrawn KR20180030092A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562191982P 2015-07-13 2015-07-13
US62/191,982 2015-07-13
PCT/US2016/041981 WO2017011492A1 (en) 2015-07-13 2016-07-13 Methods for retrievable information storage using nucleic acids

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KR20180030092A true KR20180030092A (ko) 2018-03-21

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US (3) US9928869B2 (enExample)
EP (1) EP3322812B1 (enExample)
JP (2) JP6920275B2 (enExample)
KR (1) KR20180030092A (enExample)
CN (1) CN108026557A (enExample)
WO (1) WO2017011492A1 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200141927A (ko) * 2019-06-10 2020-12-21 서울대학교산학협력단 교차 수렴법을 이용한 정보가 저장된 폴리머의 제조방법
KR20240031854A (ko) * 2022-09-01 2024-03-08 서울대학교산학협력단 정보 저장용 서열 정의 고분자의 제조방법, 정보 저장 방법, 정보 디코딩 방법 및 정보 저장용 서열 정의 고분자
KR20240114597A (ko) * 2023-01-17 2024-07-24 서울대학교산학협력단 정보 저장용 서열 정의 고분자의 제조방법, 정보 저장 방법, 정보 디코팅 로직 구축 방법 및 정보 디코딩 방법

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4610368B1 (en) 2013-08-05 2026-02-04 Twist Bioscience Corporation De novo synthesized gene libraries
WO2016126882A1 (en) 2015-02-04 2016-08-11 Twist Bioscience Corporation Methods and devices for de novo oligonucleic acid assembly
US9981239B2 (en) 2015-04-21 2018-05-29 Twist Bioscience Corporation Devices and methods for oligonucleic acid library synthesis
IL258164B (en) 2015-09-18 2022-09-01 Twist Bioscience Corp Methods for modulating protein and cellular activity and method for nucleic acid synthesis
CN108698012A (zh) 2015-09-22 2018-10-23 特韦斯特生物科学公司 用于核酸合成的柔性基底
CN115920796A (zh) 2015-12-01 2023-04-07 特韦斯特生物科学公司 功能化表面及其制备
SG11201901563UA (en) 2016-08-22 2019-03-28 Twist Bioscience Corp De novo synthesized nucleic acid libraries
JP6871364B2 (ja) 2016-09-21 2021-05-12 ツイスト バイオサイエンス コーポレーション 核酸に基づくデータ保存
ES2870639T3 (es) 2016-10-24 2021-10-27 Geneinfosec Inc Ocultación de información presente en los ácidos nucleicos
US10650312B2 (en) 2016-11-16 2020-05-12 Catalog Technologies, Inc. Nucleic acid-based data storage
AU2017363139B2 (en) 2016-11-16 2023-09-21 Catalog Technologies, Inc. Nucleic acid-based data storage
AU2017378492B2 (en) 2016-12-16 2022-06-16 Twist Bioscience Corporation Variant libraries of the immunological synapse and synthesis thereof
EP4556433A3 (en) * 2017-02-22 2025-08-06 Twist Bioscience Corporation Nucleic acid based data storage
WO2018170169A1 (en) 2017-03-15 2018-09-20 Twist Bioscience Corporation Variant libraries of the immunological synapse and synthesis thereof
WO2018217689A1 (en) * 2017-05-22 2018-11-29 The Charles Stark Draper Laboratory, Inc. Modified template-independent dna polymerase
US11174512B2 (en) 2017-05-31 2021-11-16 Molecular Assemblies, Inc. Homopolymer encoded nucleic acid memory
US10982276B2 (en) 2017-05-31 2021-04-20 Molecular Assemblies, Inc. Homopolymer encoded nucleic acid memory
US11612873B2 (en) * 2017-05-31 2023-03-28 Molecular Assemblies, Inc. Homopolymer encoded nucleic acid memory
CN111566209B (zh) 2017-06-12 2024-08-30 特韦斯特生物科学公司 无缝核酸装配方法
WO2018231864A1 (en) 2017-06-12 2018-12-20 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
CN109300508B (zh) 2017-07-25 2020-08-11 南京金斯瑞生物科技有限公司 一种dna数据存储编码解码方法
WO2019040871A1 (en) * 2017-08-24 2019-02-28 Miller Julian DEVICE FOR ENCODING AND STORING INFORMATION USING ARTIFICIALLY EXPANDED ALPHABETS OF NUCLEIC ACIDS AND OTHER ANALOGOUS POLYMERS
EP3681906A4 (en) 2017-09-11 2021-06-09 Twist Bioscience Corporation GPCR-BINDING PROTEINS AND THEIR SYNTHESIS
WO2019079802A1 (en) * 2017-10-20 2019-04-25 President And Fellows Of Harvard College METHODS OF HIGH-RATE ENCODING AND DECODING OF INFORMATION STORED IN DNA
KR102889470B1 (ko) 2017-10-20 2025-11-21 트위스트 바이오사이언스 코포레이션 폴리뉴클레오타이드 합성을 위한 가열된 나노웰
CA3088911A1 (en) 2018-01-04 2019-07-11 Twist Bioscience Corporation Dna-based storage device and method for synthesizing polynucleotides using the device
AU2019236289B2 (en) 2018-03-16 2024-12-05 Catalog Technologies, Inc. Chemical methods for nucleic acid-based data storage
EP3542903A1 (en) * 2018-03-22 2019-09-25 IMEC vzw Memory writing
EP3547315B1 (en) * 2018-03-26 2021-01-27 IMEC vzw Method of storing data
KR102138864B1 (ko) 2018-04-11 2020-07-28 경희대학교 산학협력단 Dna 디지털 데이터 저장 장치 및 저장 방법, 그리고 디코딩 방법
EP3794598A1 (en) 2018-05-16 2021-03-24 Catalog Technologies, Inc. Compositions and methods for nucleic acid-based data storage
WO2019222650A1 (en) 2018-05-17 2019-11-21 The Charles Stark Draper Laboratory, Inc. Apparatus for high density information storage in molecular chains
WO2019222706A1 (en) 2018-05-18 2019-11-21 Twist Bioscience Corporation Polynucleotides, reagents, and methods for nucleic acid hybridization
EP3826762A1 (en) * 2018-07-23 2021-06-02 DNA Script Massively parallel enzymatic synthesis of nucleic acid strands
CA3108400A1 (en) 2018-08-03 2020-02-06 Catolog Technologies, Inc. Systems and methods for storing and reading nucleic acid-based data with error protection
CN110867213B (zh) * 2018-08-28 2023-10-20 华为技术有限公司 一种dna数据的存储方法和装置
US11017170B2 (en) 2018-09-27 2021-05-25 At&T Intellectual Property I, L.P. Encoding and storing text using DNA sequences
CN112771215A (zh) 2018-09-28 2021-05-07 哈佛学院院长等 使用分子混合物存储信息
US11197827B2 (en) * 2018-10-31 2021-12-14 Microsoft Technology Licensing, Llc Polynucleotide encapsulation and preservation using self-assembling membranes
CN113423841A (zh) 2018-12-13 2021-09-21 Dna斯克瑞普特公司 细胞和生物分子上的直接寡核苷酸合成
US11249941B2 (en) * 2018-12-21 2022-02-15 Palo Alto Research Center Incorporated Exabyte-scale data storage using sequence-controlled polymers
CA3124980A1 (en) 2018-12-26 2020-07-02 Twist Bioscience Corporation Highly accurate de novo polynucleotide synthesis
JP2022521551A (ja) 2019-02-26 2022-04-08 ツイスト バイオサイエンス コーポレーション Ｇｌｐ１受容体の変異体核酸ライブラリ
CN113785057A (zh) 2019-02-26 2021-12-10 特韦斯特生物科学公司 用于抗体优化的变异核酸文库
WO2020185896A1 (en) * 2019-03-11 2020-09-17 President And Fellows Of Harvard College Methods for processing and storing dna encoding formats of information
US11989216B2 (en) * 2019-04-09 2024-05-21 University Of Washington Systems and methods for providing similarity-based retrieval of information stored in DNA
JP7586839B2 (ja) 2019-05-09 2024-11-19 カタログ テクノロジーズ， インコーポレイテッド Ｄｎａに基づくデータ記憶における探索、算出、および索引付けのためのデータ構造および動作
GB201907460D0 (en) 2019-05-27 2019-07-10 Vib Vzw A method of storing information in pools of nucleic acid molecules
US20210147833A1 (en) * 2019-05-31 2021-05-20 Illumina, Inc. Systems and methods for information storage and retrieval using flow cells
SG11202012827VA (en) 2019-05-31 2021-01-28 Illumina Inc Obtaining information from a biological sample in a flow cell
CN110427786A (zh) * 2019-05-31 2019-11-08 西藏自治区人民政府驻成都办事处医院 一种用dna作为文字信息高效存储介质的方法
AU2020298294A1 (en) 2019-06-21 2022-02-17 Twist Bioscience Corporation Barcode-based nucleic acid sequence assembly
CN112242978B (zh) * 2019-07-18 2023-04-07 京东科技控股股份有限公司 一种处理数据的方法和装置
US11773422B2 (en) 2019-08-16 2023-10-03 Microsoft Technology Licensing, Llc Regulation of polymerase using cofactor oxidation states
WO2021041667A1 (en) * 2019-08-27 2021-03-04 President And Fellows Of Harvard College Modifying messages stored in mixtures of molecules using thin-layer chromatography
US11795450B2 (en) 2019-09-06 2023-10-24 Microsoft Technology Licensing, Llc Array-based enzymatic oligonucleotide synthesis
US12091777B2 (en) 2019-09-23 2024-09-17 Twist Bioscience Corporation Variant nucleic acid libraries for CRTH2
WO2021061842A1 (en) 2019-09-23 2021-04-01 Twist Bioscience Corporation Variant nucleic acid libraries for single domain antibodies
JP7726874B2 (ja) 2019-10-11 2025-08-20 カタログ テクノロジーズ， インコーポレイテッド 核酸セキュリティーおよび認証
BR112022011235A2 (pt) 2019-12-09 2022-12-13 Twist Bioscience Corp Bibliotecas de variantes de ácido nucleico para receptores de adenosina
CN111489791B (zh) * 2020-04-07 2023-05-26 中国科学院重庆绿色智能技术研究院 固态纳米孔高密度编码dna数字存储读取方法
EP4150622B1 (en) 2020-05-11 2024-09-25 Catalog Technologies, Inc. Programs and functions in dna-based data storage
CN114058471A (zh) * 2020-07-29 2022-02-18 东南大学 负载了dna存储数据的数据存储装置、制备方法和读数方法
CN112288089B (zh) * 2020-09-28 2022-12-20 清华大学 阵列式核酸信息存储方法及装置
US12344876B2 (en) 2020-10-30 2025-07-01 Microsoft Technology Licensing, Llc Spatially addressable control of polymerase activity
CN118103519A (zh) * 2021-06-14 2024-05-28 普里姆罗斯生物公司 用于酶促核酸合成的方法
EP4377476A4 (en) * 2021-07-28 2025-06-18 NAIO, Inc. Compositions, systems, and methods for nucleic acid data storage
TWI869710B (zh) * 2021-09-29 2025-01-11 呈堯 陳 用於無模板ｒｎａ合成的核酸聚合酶變體、試劑套組及方法
WO2024026084A2 (en) * 2022-07-29 2024-02-01 Arizona Board Of Regents On Behalf Of The University Of Arizona Systems and methods for storage of digital information via biopolymers
DE102023204133A1 (de) * 2023-05-04 2024-11-07 Siemens Healthineers Ag Verfahren zum Bereitstellen eines Datenelementes
WO2025235993A1 (en) * 2024-05-10 2025-11-13 Tsui Tsz Kin Martin Methods and compositions for encoding and storing electronic data in biological contexts

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5917031A (en) 1996-04-19 1999-06-29 Taiko Pharmaceutical Co., Ltd. Method of synthesizing polydeoxyribonucleotides
AU4703300A (en) 1999-05-06 2000-11-21 Mount Sinai School Of Medicine Of The City University Of New York, The Dna-based steganography
US7056661B2 (en) * 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
WO2002092813A1 (en) 2001-05-11 2002-11-21 Matsushita Electric Industrial Co., Ltd. Biomolecular substrate and method and apparatus for examination and diagnosis using the same
WO2003025123A2 (en) 2001-08-28 2003-03-27 Mount Sinai School Of Medecine Dna: a medium for long-term information storage specification
GB0201966D0 (en) 2002-01-29 2002-03-13 Smartwater Ltd Improvements in or relating to security products
US20030228611A1 (en) * 2002-05-01 2003-12-11 President And Fellows Of Harvard College Nucleic acid memory device
US20040060987A1 (en) 2002-05-07 2004-04-01 Green Larry R. Digital image analysis method for enhanced and optimized signals in fluorophore detection
US20040001371A1 (en) 2002-06-26 2004-01-01 The Arizona Board Of Regents On Behalf Of The University Of Arizona Information storage and retrieval device using macromolecules as storage media
US7158892B2 (en) * 2002-06-28 2007-01-02 International Business Machines Corporation Genomic messaging system
JP4102157B2 (ja) 2002-10-17 2008-06-18 正幸 園部 生体高分子を通信媒体もしくは記録媒体とした、情報通信方法、情報記録方法、エンコーダおよびデコーダ
US20050053968A1 (en) 2003-03-31 2005-03-10 Council Of Scientific And Industrial Research Method for storing information in DNA
US7628096B2 (en) * 2004-03-25 2009-12-08 Teleflex Corporated Pedal mount assembly
US7874489B2 (en) 2005-06-20 2011-01-25 Authentiform Technologies, Llc Product authentication
WO2007002016A2 (en) 2005-06-20 2007-01-04 Johnson & Johnson Systems and methods for product authentication
US20070113137A1 (en) * 2005-10-22 2007-05-17 Ho Seung Ryu Error Correction in Binary-encoded DNA Using Linear Feedback Shift Registers
DK2171088T3 (en) 2007-06-19 2016-01-25 Stratos Genomics Inc Nucleic acid sequencing in a high yield by expansion
DE102007057802B3 (de) 2007-11-30 2009-06-10 Geneart Ag Steganographische Einbettung von Informationen in kodierenden Genen
US20110003701A1 (en) 2008-02-27 2011-01-06 454 Life Sciences Corporation System and method for improved processing of nucleic acids for production of sequencable libraries
DK2856375T3 (en) * 2012-06-01 2018-11-05 European Molecular Biology Laboratory High capacity storage of digital information in DNA
CN108875312A (zh) * 2012-07-19 2018-11-23 哈佛大学校长及研究员协会 利用核酸存储信息的方法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200141927A (ko) * 2019-06-10 2020-12-21 서울대학교산학협력단 교차 수렴법을 이용한 정보가 저장된 폴리머의 제조방법
KR20240031854A (ko) * 2022-09-01 2024-03-08 서울대학교산학협력단 정보 저장용 서열 정의 고분자의 제조방법, 정보 저장 방법, 정보 디코딩 방법 및 정보 저장용 서열 정의 고분자
KR20240114597A (ko) * 2023-01-17 2024-07-24 서울대학교산학협력단 정보 저장용 서열 정의 고분자의 제조방법, 정보 저장 방법, 정보 디코팅 로직 구축 방법 및 정보 디코딩 방법

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