KR20180001208A - Anticancer Injectable Preparation Equipment - Google Patents

Abstract

The present invention relates to an anticancer injection solution manufacturing device comprising: a sterile manufacturing stand which is installed in a sterile room and has a pharmacy room for manufacturing an anticancer injection solution; a plurality of anticancer drug vials which is installed to be connected to the sterile manufacturing stand and accommodates anticancer drugs; an infusion solution container which accommodates an infusion solution mixed with the anticancer drug; a supplying unit which supplies an article container containing a mixing container for mixing the anticancer drug with the infusion solution to the sterile manufacturing stand; a preparation unit which uses a syringe to extract the anticancer drug and the infusion solution supplied from the supplying unit, respectively, and injects the same into the mixing container to manufacture an anticancer injection solution; and a discharging unit which is installed to be connected to the sterile manufacturing stand, and discharges the article container containing the anticancer infusion solution manufactured by the preparation unit from the sterile manufacturing stand. The purpose of the present invention is to provide an anticancer injection solution manufacturing device which can automatize processes of extracting medicine necessary for manufacturing anticancer injection solution, injecting the same, and moving articles such as vials and mixing containers.

Description

{Anticancer Injectable Preparation Equipment}

TECHNICAL FIELD The present invention relates to a device for preparing an anticancer injection, and more particularly, to a device for preparing an anticancer drug by injecting, preparing, and delivering medicines through an automated facility.

Generally, anticancer injections are prepared by injecting an anticancer agent and a liquid at a certain ratio and injecting them into an intravenous injection form.

Conventional anticancer injection methods include a non-autotrophic preparation method in which a pharmacist directly handles an anticancer drug from a vial using a syringe and mixes it with liquid, a manually prepared drug preparation product A semiautomatic preparation method for preparing injections through cooperation between a preparer and a mechanical device utilizing the method, and an electronic type preparation method for performing a complete preparation operation only by a machine.

The non-autotrophic dispensing method is directly exposed to an anticancer drug having a toxic agent, so that there is a danger that the dispenser may cause a disease, and there is a problem of inducing musculoskeletal diseases by repeated preparations.

The semiautomatic preparation method complements the problems of the non-autotective preparation method and performs the preparation work through the fusion between the preparation agent and the quantitative preparation automatic apparatus. However, it is impossible to continuously prepare the composition in the case of a batch preparation requiring a large amount of preparation, There is a falling problem.

Although the electronic stereosystem can electronically assemble a large amount of preparation, it has a problem that the price is high and the penetration rate is low, and the size of the dispenser is large, so that it can not be installed in a narrow space.

Accordingly, the above-described problems of the conventional methods of preparing anticancer injections are overcome. For example, there is a desperate need for securing the safety of the drug maker for the anticancer drug through the partial automation, preventing the musculoskeletal disease of the drug maker from occurring, preparing a batch preparation and outpatient preparation according to the possibility of continuous preparation, and developing a middle-

Disclosure of Invention Technical Problem [8] Accordingly, the present invention has been made to solve the above-mentioned problems, and it is an object of the present invention to provide an apparatus for preparing an anticancer injection drug capable of automating the movement of articles such as a drug extraction, injection,

In order to solve the above-described problems, the present invention can include the following configuration.

The apparatus for preparing an anti-cancer injecting agent according to the present invention comprises an aseptic preparation vessel equipped with a preparation chamber for preparing an anti-cancer injection agent installed in a clean room; A sterilizing tank for supplying the sterilizing agent to the article container including a plurality of anticancer agent vials connected to the aseptic preparation stand and containing the anticancer agent, a liquid container containing the liquid mixed with the anticancer agent, and a mixing container for mixing the anticancer agent and the liquid solution, ; A preparation unit for extracting the anticancer agent and the liquid solution supplied from the supply unit using a syringe and injecting the same into the mixing container to prepare an anticancer injection; And a carry-out unit connected to the aseptic dispenser for taking out the article container including the anti-cancer injectant prepared in the dispenser from the aseptic tank.

In the apparatus for preparing an anticancer injection according to the present invention, the supply unit and the carry-out unit may be a conveyor for supporting and transporting the article container.

In the apparatus for preparing an anticancer injection according to the present invention, the preparation unit may include an article container mechanism for moving the article container, and a syringe mechanism for moving the syringe. The syringe mechanism may grip and move a syringe from a syringe container in which a plurality of syringes are releasably coupled.

In the apparatus for preparing an anti-cancer injectate according to the present invention, the article container mechanism includes an article supporting member for supporting the article container supplied from the supplying section, an article ascending / descending member for ascending / descending the article supporting member, Direction moving member for moving the article in the left-right direction.

The syringe device may further include a syringe holding member for gripping one syringe from the syringe container, a syringe holding member for holding the syringe holding member in a forward direction toward the inside from the outside of the sterile syringe barrel, A syringe moving member for moving the syringe holding member in a backward direction opposite to the syringe moving member, a syringe moving member for moving the syringe holding member movably coupled to the syringe moving member, A syringe rotating member coupled to the syringe rotating member for rotating the syringe holding member such that the syringe is vertically arranged in one of the anti-cancer drug vial, the infusion container, and the mixing container; And a syringe elevating member Coupled to move the elevating member and fraud may include a syringe piston moving member for moving the piston of the syringe.

In the apparatus for preparing an anti-cancer injectate according to the present invention, the article container mechanism and the syringe mechanism may move the article container and the syringe such that the article container and the syringe are positioned at preparation positions for preparing the anti- have.

In the apparatus for preparing an anti-cancer injectate according to the present invention, the article container mechanism may include a support position for supporting the article container supplied from the supply unit, a preparation position for preparing the anti-cancer injection agent, The article support member may be moved so that the article support member is positioned at an unloading position for taking out the prepared anti-cancer injection agent.

In the apparatus for preparing an injection apparatus for an anticancer drug according to the present invention, the syringe mechanism is arranged so that the syringe grasping member is positioned at a gripping position for gripping one syringe from the syringe container and a dispensing position for preparing the anti- The gripping member can be moved.

The apparatus for preparing an anti-cancer injectate according to the present invention may include a syringe container rotating unit for rotating the syringe container to selectively hold one of a plurality of syringes coupled to the syringe container by the syringe holding member.

In the apparatus for preparing an anti-cancer injectate according to the present invention, the preparation unit may further include an anti-cancer agent contained in the mixing container and an electronic balance for checking the weight of the infusion solution.

The apparatus for preparing an anticancer injection according to the present invention may further include an information input unit for inputting prescription information describing the components of the anticancer drug and storing information on the components of the prepared anticancer drug.

The information input unit may include a barcode reader for reading prescription information transmitted from a barcode label attached to the article container through interfacing with a hospital network and article information included in the article container, Display and store information entered via a bar code reader, prepare a chemotherapeutic injection, and a touch screen for transmitting information to the hospital network.

According to the present invention, the following effects can be obtained.

The present invention automates the chemical extraction, injection and movement of articles necessary for the preparation of anti-cancer injections, thereby reducing the work of the dispenser for the preparation of anti-cancer injections, securing the safety of the dispenser and preventing musculoskeletal diseases, Can be prepared.

1 is a schematic overall configuration diagram of an apparatus for preparing an injection preparation for a cancer according to the present invention
FIG. 2 is a schematic front view showing essential parts of an apparatus for preparing an injection preparation for an anti-cancer injection according to the present invention
3 is a schematic plan view showing essential parts of the apparatus for preparing an anti-cancer injectate according to the present invention
FIG. 4 is a schematic side view for explaining a syringe mechanism in the apparatus for preparing an anti-cancer injectate according to the present invention
FIG. 5 is an operating state diagram for explaining the movement of the article container mechanism to the preparation position in the apparatus for preparing an anti-cancer injectate agent according to the present invention
FIG. 6 is an operational state diagram for explaining preparation of an anti-cancer injection agent at a preparation position in the apparatus for preparing an anti-cancer injection agent according to the present invention
7 is an operational state diagram illustrating the movement of the article container in the apparatus for preparing an anti-cancer injectate according to the present invention to the take-out position
8 is a schematic plan view for explaining a carry-out part in the apparatus for preparing an anti-cancer injectate according to the present invention

It should be noted that, in the specification of the present invention, the same reference numerals as in the drawings denote the same elements, but they are numbered as much as possible even if they are shown in different drawings.

Meanwhile, the meaning of the terms described in the present specification should be understood as follows.

The word " first, "" second," and the like, used to distinguish one element from another, are to be understood to include plural representations unless the context clearly dictates otherwise. The scope of the right should not be limited by these terms.

It should be understood that the terms "comprises" or "having" does not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, or combinations thereof.

It should be understood that the term "at least one" includes all possible combinations from one or more related items. For example, the meaning of "at least one of the first item, the second item and the third item" means not only the first item, the second item or the third item, but also the second item and the second item among the first item, Means any combination of items that can be presented from more than one.

BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, an apparatus for preparing an anti-cancer injecting agent according to the present invention will be described in detail with reference to the accompanying drawings.

2 is a schematic front view showing the main components of the apparatus for preparing an anti-cancer injectable preparation according to the present invention, and Fig. 3 is a schematic view of the apparatus for preparing an anti-cancer injectable preparation according to the present invention FIG. 4 is a schematic side view for explaining a syringe mechanism in the apparatus for preparing an anti-cancer injectate according to the present invention, and FIG. 5 is a schematic plan view for explaining a syringe mechanism in the apparatus for preparing an anti- 6 is an operational state diagram for explaining the preparation of the anti-cancer injection agent at the preparation position in the apparatus for preparing an anti-cancer injection agent according to the present invention, and Fig. 7 is an operational state diagram for explaining the movement of the anti- In order to explain the movement of the article container mechanism to the take-out position Statue attitude, Figure 8 is a schematic plan view illustrating parts taken out from the anti-cancer injection preparation according to the present invention.

1 to 8, the apparatus 1 for preparing an anti-cancer injectate according to the present invention automatically supplies an article container containing an article such as an anti-cancer agent, liquid, etc. for preparing an anti-cancer injecting agent to a preparation unit for preparing an anti- And to automatically release the anticancer injections prepared in the dispenser.

To this end, the apparatus 1 for preparing an anti-cancer injectate according to the present invention mainly comprises a sterilized manufacturing base 2, a supply unit 3, a carry-out unit 4, and a preparation unit 5.

The article container 100 may include an anticancer agent vial 110 containing an anticancer agent, a transfusion container 120 containing a fluid for mixing with the anticancer agent, and a mixing container 130 for mixing the anticancer agent and the fluid. The anticancer agent vial 110, the infusion container 120 and the mixing container 130 may be arranged in a row in the article container 100, but the present invention is not limited thereto. . At least one of the anticancer agent vial 110 and the liquid receiver 120 may be loaded in the article container 100. The anticancer drug vial 110, the fluid container 120 and the mixing container 130 may be disposed and loaded in the article container 100 by a dispenser outside the aseptic manufacturing stand 2. The article container 100 can be supported by the supply unit 3 and moved to the preparation unit 5 from the outside of the aseptic manufacturing stand 2.

Hereinafter, the aseptic manufacturing stand 2, the supply unit 3, the take-out unit 4, and the preparation unit 5 will be described in detail with reference to the accompanying drawings.

Referring to Figs. 1 to 8, the aseptic manufacturing stand 2 provides a space for preparing an anticancer injection.

The aseptic dispenser (2) is installed so that a pharmacist or an administrator can easily carry out a dispenser operation. A support portion 21 is provided below the aseptic dispenser stand 2 so that the aseptic dispenser stand 2 is spaced apart from the floor by a predetermined height. On the upper part of the support part 21, a preparation room 22, which is a space for performing a preparation facility and a preparation work, is provided. The dispenser 5 may be installed in the dispenser 22.

The aseptic dispenser 2 is installed in a sterile room, but is not limited thereto. At least one dispenser may be disposed in the dispensing chamber 22 to perform an operation of preparing an anticancer injection.

The preparation chamber 22 is formed partially open when viewed from the front, and a preparation space may be provided therein. The dispensing chamber 22 is provided with a table 23 for placing equipment and articles so that the dispenser can carry out the dispensing work by handling the equipment and the goods through the open portion. The aseptic dispenser (2) may be installed to be connected to the supply unit (3) and the carry-out unit (4).

The supply unit 3 is installed to connect the outside and the inside of the aseptic dispenser 2. The supply unit 3 is for supplying the article container 100 to the preparation unit 5 provided on the table 23 of the aseptic preparation table 2 outside the aseptic preparation table 2. The supplying unit 3 may be installed at the same height as the height of the preparing unit 5 from the floor so as to supply the article container 100 to the preparing unit 5. [ The supply unit 3 moves the article container 100 from the outside of the aseptic dispenser 2 to the inside of the aseptic dispenser 2 so that the article container 100 is placed in the dispenser 5 Can supply. The supply unit 3 can support the article container 100 supplied from the dispenser outside the aseptic dispenser 2 and move it into the sterile dispenser base 2. [ The supplying unit 3 may be a conveyor rotating between the outside and the inside of the aseptic dispenser 2. The dispenser may set an anticancer drug vial 110 containing different types of anticancer drugs in the product container 100 depending on the patient.

The supply unit 3 can move the plurality of article containers 100. The supply unit 3 sequentially loads a plurality of the article containers 100 set outside the aseptic dispenser 2 differently according to the patients, so that the plurality of the article containers 100 are sequentially It can be moved to the preparation section 5. The supply unit 3 stops rotating when one of the plurality of article containers 100 is supplied to the preparation unit 5 and the product container 100 supplied to the preparation unit 5 Is delivered to the outside of the aseptic dispensation chamber (2) through the take-out part (4), the dispenser (5) can be rotated to sequentially supply the other article containers (100). The article container 100 supplied by the supply part 3 can be supported by the preparation part 5 at the support position LP (shown in Fig. 3).

The take-out unit 4 is installed so as to connect the outside of the aseptic dispenser 2 and the inside thereof. The take-out unit 4 is for taking out the article container 100 supplied from the preparation unit 5 to the outside of the sterile dispenser stand 2. In this case, the article container 100 supplied from the preparation unit 5 may contain an anti-cancer injectable preparation prepared by mixing an anti-cancer agent and a sap. The takeout unit 4 can take out the article container 100 positioned at the take-out position (ULP, shown in Fig. 3) by the preparation unit 5. [ The take-out unit 4 may be installed at the same height as the supply unit 3. The carry-out part 4 may be a conveyor rotating between the inside and the outside of the aseptic dispenser 2.

The carry-out unit 4 can take out the article containers 100 sequentially supplied from the preparation unit 5 to the outside of the sterile dispenser 2 one by one. The article container 100 including the anti-cancer injecting agent taken out from the take-out unit 4 can be moved by the dispenser to another place such as a main fact, a pharmacy, and the like. The take-out unit 4 may stop rotating when the article container 100 is rotated in the dispenser 5 and the article container 100 is not supplied in the dispenser 5, but the present invention is not limited thereto It may be always rotating. The carry-out section 4 can rotate in a direction opposite to the direction in which the supply section 3 is rotated. For example, when the supply part 3 rotates in a first rotation direction from the outside to the inside of the aseptic dispenser 2, the carry-out part 4 is moved in the aseptic dispenser 2, It can rotate in two rotation directions. The first rotation direction may be a forward direction FD and the second rotation direction may be a reverse direction BD. The injection device for preparing an anticancer injection according to the present invention 1 is provided in such a manner that the supply part 3 and the carry-out part 4 are connected to the outside and inside of the aseptic dispenser 2, A dispenser that performs dispensing work from the outside can easily supply the container 100 to the inside of the sterile dispenser 2. Accordingly, the apparatus 1 for preparing an anticancer injection according to the present invention can reduce or prevent the occurrence of industrial disasters such as musculoskeletal diseases in a dispenser as compared with the prior art in which an anticancer injection preparation operation is performed inside the aseptic dispenser.

The preparation unit 5 is installed so as to be connected to the supply unit 3 and the carry-out unit 4. The preparation unit 5 can receive the article container 100 including the anticancer agent and the sap from the supply unit 3. [ The preparation unit 5 may extract a certain amount of the anticancer agent and the liquid solution from the article container 100 using the syringe C and inject it into the mixing container 130 to prepare the anticancer injection agent. The preparation unit 5 can move the article container 100 containing the prepared anti-cancer injectant to the take-out unit 4. [ The preparation section 5 may include an article container mechanism 51 and a syringe mechanism 52.

The article container mechanism 51 is for moving the article container 100 supplied from the supplying section 2. To this end, the article container mechanism 51 may include an article supporting member 511, an article elevating member 512, and an article moving member 513. The article container mechanism 51 includes a support position (LP, shown in FIG. 3) for supporting the article container 100 supplied from the supply unit 2 by the article support member 511, (PP) (shown in FIG. 3) and a carry-out position (ULP, shown in FIG. 3) for taking out the chemotherapeutic injection preparation prepared at the preparation position PP to the outside of the aseptic preparation table 2 (Not shown). The article container mechanism 51 moves the article support member 511 to the support position LP, the preparation position PP, and the article transport mechanism 513 using the article elevating member 512 and the article moving member 513. [ To the carry-out position (ULP). The article container 100 supplied from the supply unit 2 is supported by the article support member 511 and is positioned at the support position LP, the preparation position PP and the take-out position ULP .

The article supporting member 511 is for supporting the article container 100 supplied from the supplying section 3. When the plurality of article containers 100 are supplied from the supply unit 3, the article support members 511 can support the article containers 100 one by one. The article support member 511 may be detachably coupled to the article container 100. The article support member 511 can support the article container 100 at the support position LP. Although not shown, the article support member 511 may be coupled to an insertion groove formed in a lower portion of the article container 100 to support the article container 100. The article support member 511 may be coupled to the insertion groove as the article container 100 is moved from the supply unit 3 to the support position LP. The article support member 511 may be spaced apart from the insertion groove at the unloading position ULP, thereby not supporting the article container 100. In this case, the article container 100 can be loaded on the electronic balance or the carry-out section 4 to be described later. The article supporting member 511 may be movably coupled to the article elevating member 512.

The article elevating member 512 is for elevating and lowering the article supporting member 511. The article elevating member 512 may move the article supporting member 511 coupled to the article container 100 at the support position LP in the upward direction UD (shown in FIG. 5). The article elevating member 512 can move the raised article supporting member 511 in the lowering direction DD (shown in Fig. 7) so as to be positioned at the unloading position ULP. The article elevating member 512 may be a cylinder type using a hydraulic cylinder or a pneumatic cylinder, a gear type using a motor, a rack gear, and a pinion gear, a motor, and a ball screw (UD) and a downward direction (DD) using a ball screw system, a belt system using a motor, a pulley and a belt, a linear motor system using a coil and a permanent magnet, ). The article elevating member 512 may include an Lm block that moves along the Lm guide rail.

The article moving member 513 is for moving the article moving member 512 in the left-right direction. The article transverse moving member 513 can move the article elevating member 512 to the right (RD, shown in Fig. 2). The article transverse moving member 513 can move the article elevating member 512 to the left direction (LD, shown in Fig. 2) opposite to the right direction RD. The article supporting member 511 and the article container 100 coupled to the article elevating member 512 are moved in the right direction RD and the left direction LD by the article left and right moving member 513 . The article pivotal movement member 513 may be formed in a 'C' shape erected on the table 23 of the aseptic dispenser. The article moving member 513 is supported at one side and the other side of the table 23 to support the article elevating member 512, the article supporting member 511 and the article container 100 . The article elevating member 512 may be movably coupled to a horizontal frame of the article left and right shifting member 513 installed parallel to one side and the other side of the table 23. The article left-right moving member 513 may be a cylinder type using a hydraulic cylinder or a pneumatic cylinder, a gear type using a motor, a rack gear and a pinion gear, a motor and a ball screw, The article elevating member 512 is moved in the rightward direction RD and the leftward direction by using a ball screw system using a motor, a belt system using a motor, a pulley and a belt, a linear motor system using a coil and a permanent magnet, LD). The article moving member 513 may include an Lm block that moves along the Lm guide rail. The article carrying member 511 moves up and down the article supporting member 511 and the article moving member 513 moves the article carrying member 511 in the left and right direction, The support position LP, the preparation position PP, and the take-out position ULP, respectively. The article container 100 supported by the article supporting member 511 can be positioned at the support position LP, the preparation position PP and the unloading position ULP, respectively. The article elevating member 512 and the article moving member 513 move the article support member 511 to the take-out position ULP after passing the preparation position PP at the support position LP When the article container 100 is carried out by the carry-out part 4, the article support member 511 is moved back from the carry-out position ULP to the support position LP via the preparation position PP . Accordingly, the apparatus 1 for preparing an anticancer injection according to the present invention is configured to move the plurality of article containers 100 supplied through the supply unit 3 one by one to the preparation position PP and the removal position ULP . Accordingly, the apparatus 1 for preparing an anti-cancer injectate according to the present invention can precisely prepare and distribute an anti-cancer injection according to the prescription of each patient among a plurality of patients.

The syringe mechanism 52 is for moving the syringe C. The syringe mechanism 52 and the article container mechanism 51 are arranged such that the article container 100 and the syringe C are positioned at a preparation position PP for preparing the anti- And the syringe C can be respectively moved. In the preparation position PP, an anticancer agent and a liquid solution are extracted by the injector C and injected into the mixing container 130 to prepare an anti-cancer injecting agent. Although not shown, the anticancer agent and the liquid injected into the mixing container 130 can be mixed well by a shaker. The syringe mechanism 52 can grip and move one syringe C from a syringe container 200 in which a plurality of syringes C are detachably coupled. The syringe mechanism 52 includes a syringe holding member 521, a syringe forward / backward moving member 522, a syringe left / right moving member 523, a syringe rotating member 524, a syringe lift member 525, and a syringe piston moving member 526 ). The syringe mechanism 52 moves the syringe holding member 521 from the syringe container 200 to the gripping position GP for gripping the syringe C and the dispensing position PP from the syringe container 200 .

The syringe holding member 521 is for gripping one syringe C from the syringe container 200. The syringe container 200 may be constructed such that a plurality of syringes C are attached to the rotating plate in a circular shape outside the sterile dispensing base 2 and then installed inside the sterile dispensing base 2, Can be installed on the stand (2). The plurality of syringes may be attached to the rotating plate by various syringes such as a syringe for extracting and injecting various anticancer drugs during the preparation of anti-cancer, and a syringe for extracting the liquid when a liquid to be discarded is dispensed. At least one or more of the syringe (C) may be attached to the rotating plate. The syringe holding member 521 is moved to the sterile dispenser 2 by the syringe moving unit 522, the syringe moving unit 523, the syringe rotating member 524 and the syringe moving unit 525, To the gripping position (GP) and the dispensing position (PP). The syringe holding member 521 may hold the upper portion of the syringe C. The syringe holding member 521 may be formed as a whole shape. The syringe holding member 521 is moved from the gripping position GP to the backward direction BD by the syringe forward and backward moving member 522 so as to grip the upper portion of the syringe C . The syringe holding member 521 is moved in the advancing direction FD (shown in Fig. 3) opposite to the backward direction by the syringe forward / backward moving member 522, thereby moving the gripped syringe C to the syringe container 200). The forward direction (FD) is the direction from the outside to the inside of the aseptic dispenser base (2). The syringe holding member 521 is formed to have the same size as the diameter of the syringe C so that the syringe C may not be dropped even if the syringe holding member 521 moves while gripping the syringe C. The syringe piston moving member 526 may be moved by the syringe longitudinal movement member 522 to catch the lower portion of the syringe C.

The syringe longitudinal movement member 522 is for moving the syringe grasping member 521 in the forward direction FD and the backward direction BD. The syringe forward and backward moving member 522 moves the syringe left and right moving member 523 in the forward direction FD and the backward direction BD to move the syringe holding member 521 in the advancing direction FD and in the forward direction It is possible to move to the backward direction BD. The syringe holder 521 is moved to the syringe container 200 after gripping one of the syringes mounted on the syringe container 200 at the gripping position GP, As shown in Fig. The syringe longitudinal movement member 522 moves in the retracting direction BD at the gripping position GP so as to grip the syringe C. The syringe reciprocating member 522 is moved in the advancing direction FD so that the held syringe C can be separated from the syringe container 200. [ The syringe back and forth moving member 522 may be a cylindrical type using a hydraulic cylinder or a pneumatic cylinder, a gear type using a motor and a rack gear and a pinion gear, a motor and a ball screw, The syringe left and right moving member 523 is moved in the forward direction FD and the backward direction by using a ball screw method using a motor, a belt method using a motor, a pulley and a belt, a linear motor method using a coil and a permanent magnet, (BD). The syringe longitudinal movement member 522 may include an Lm block that moves along the Lm guide rail.

The syringe left and right movable member 523 may be movably coupled to the syringe longitudinal movement member 522. The syringe left and right movable member 523 can be moved in the forward direction FD and the backward direction BD by the syringe longitudinal movement member 522. [ The syringe left and right movable member 523 is for moving the syringe holding member 521 in the lateral direction. The syringe left and right moving member 523 can move the syringe holding member 521 in the left and right direction by moving the syringe rotating member 524 and the syringe lift member 525 in the left and right directions. The syringe left and right movable member 523 can move the syringe holding member 521 in the rightward direction RD and the leftward direction LD. Accordingly, the syringe C gripped by the syringe holding member 521 can be moved in the rightward direction RD and the leftward direction LD. The syringe left and right shifting member 523 may be installed in a 'C' shape erected on the syringe longitudinal movement member 522. In this case, when the upper frame constituting the upper part of the syringe left and right moving member 523 is moved in the forward direction FD and the backward direction BD, the syringe holding member 521 approaches the syringe container 200 To the gripping position (GP). Accordingly, the syringe holding member 521 may be moved to the protruded side and positioned on the same line as the gripping position GP. The same line as the gripping position GP may mean an axial direction in which the syringe left and right shifting member 523 is advanced and retracted by the syringe forward and backward shifting member 522. The syringe left and right shifting member 523 may be a cylinder type using a hydraulic cylinder or a pneumatic cylinder, a gear type using a motor and a rack gear and a pinion gear, a motor and a ball screw, The syringe holding member 521 is moved in the rightward direction RD and the leftward direction by using a ball screw system using a motor, a belt system using a motor, a pulley and a belt, a linear motor system using a coil and a permanent magnet, LD). The syringe left and right movable member 523 may include an Lm block that moves along the Lm guide rail.

The syringe rotating member 524 may be rotatably coupled to the syringe left and right shifting member 523. The syringe rotating member 524 is disposed in the syringe so that the syringe C is vertically aligned on any one of the anticancer agent vial 110, the fluid receiver 120 and the mixing vessel 130 of the product container 100. [ And is for rotating the gripping member 521. The syringe rotating member 524 can rotate the syringe holding member 521 clockwise and counterclockwise by rotating the syringe lifting member 525. [ The syringe rotating member 524 may be a motor for generating a driving force for rotating the syringe elevating member 525.

The syringe lifting member 525 may be rotatably coupled to the syringe rotating member 524. The syringe lifting member 525 is for lifting the syringe holding member 521. The syringe lifting member 525 can move the syringe holding member 521 in the upward direction UD and the downward direction DD. The syringe lifting member 525 moves the syringe C from the anticancer vial 110 to the infusion container 120 and the mixing container 130 by moving the syringe holding member 521 in the upward direction UD. The needle of the syringe C can be inserted. In this case, the injector C may inject the anticancer agent or the extract solution extracted or extracted from the anti-cancer agent or the liquid into the mixing container 130. The syringe lifting member 525 moves the syringe C from the anticancer vial 110 to the infusion container 120 and the mixing container 130 by moving the syringe holding member 521 in the downward direction DD. It can be separated from any one of them. In this case, the injector C may be spaced apart from the anticancer agent vial 110 or the infusion vessel 120 in the state of extracting the anticancer agent or the sap. The injector C may be spaced apart from the mixing vessel 130 after injecting an anti-cancer agent or liquid into the mixing vessel 130. The syringe lifting member 525 may be a cylinder type using a hydraulic cylinder or a pneumatic cylinder, a gear type using a motor, a rack gear, and a pinion gear, a motor, and a ball screw The syringe grasping member 521 is moved in the upward direction UD and the downward direction DD by using a ball screw system, a belt system using a motor, a pulley and a belt, a linear motor system using a coil and a permanent magnet, ). The syringe elevating member 525 may include an Lm block that moves along the Lm guide rail. The syringe lifting member 525 may move up and down the syringe piston moving member 526 coupled to the syringe holding member 521 by moving the syringe holding member 521 up and down.

The syringe piston moving member 526 is movably coupled to the syringe elevating member 525. The syringe piston moving member 526 is for moving a syringe piston installed in the syringe C. The syringe piston moving member 526 may be coupled to the thumb presser of the syringe connected to the syringe piston by the syringe longitudinal movement member 522 at the gripping position GP. The syringe piston moving member 526 moves the syringe piston in the upward direction UD and the downward direction DD by moving the thumb pressing bar of the syringe in the upward direction UD and the downward direction DD have. Accordingly, the syringe piston can be elevated inside the syringe (C). The syringe piston moving member 526 moves the syringe piston in a state in which the syringe C is in contact with or inserted into any one of the chemo-vial 110, the fluid receiver 120, . The syringe piston moving member 526 moves the syringe piston in the descending direction DD to extract the anticancer agent or the sap from the anticancer agent vial 110 or the infusion vessel 120 into the syringe C have. The syringe piston moving member 526 moves the syringe piston in the upward direction UD to inject the extracted anticancer agent or liquid into the interior of the syringe C to the outside of the syringe C. In this case, the anticancer agent or the sap may be injected into the mixing vessel 130. Accordingly, in the mixing vessel 130, an anticancer drug and a liquid solution are mixed to prepare an anticancer injectable drug. The syringe piston moving member 526 may be a cylinder type using a hydraulic cylinder or a pneumatic cylinder, a gear type using a motor and a rack gear and a pinion gear, a motor and a ball screw, (UD) and a downward direction (DD) using a ball screw system using a motor, a belt system using a pulley and a belt, a linear motor system using a coil and a permanent magnet, Can be moved. The syringe piston moving member 526 may include an Lm block that moves along an Lm Guide Rail installed on the syringe holding member 521. [

Therefore, the apparatus 1 for preparing an anti-cancer injectate according to the present invention realizes partial automation for the preparation of the anti-cancer injecting agent through the supplying unit 3, the taking-out unit 4 and the preparing unit 5, It is possible to secure the safety and prevent the musculoskeletal diseases and reduce the cost of the injection device for the cancer injection.

The apparatus 1 for preparing an anti-cancer injectate according to the present invention may further include a syringe container rotating unit 6.

The syringe container rotation unit 6 is for rotating the syringe container 200. The syringe container rotating part 6 may be installed in the aseptic dispenser 2 to generate a driving force for rotating the syringe container 200. A dispenser for preparing a chemotherapeutic injection may mount the syringe container 200 on the syringe container rotating part 6 by setting the syringe container 200 outside the aseptic dispenser 2. The syringe container rotation unit 6 may rotate the syringe container 200 such that the syringe holding member 521 selectively grasps any one of a plurality of syringes coupled to the syringe container 200. [ The syringe container rotating part 6 is moved so that the syringe holding member 521 is moved in the backward direction BD to grip one of the plurality of syringes C at the gripping position GP, The syringe container 200 can be rotated such that the syringe container 521 coincides with the moving line moving in the backward direction BD. The syringe container rotation unit 6 may rotate the syringe container 200 such that the syringe holding member 521 grasps a syringe suitable for the operation of preparing the anti-cancer injection agent and discharging the unnecessary solution. The syringe container rotation unit 6 may rotate the syringe container 200 manually by the operation of the dispenser. However, the syringe container rotation unit 6 may be connected to an information input unit, which will be described later, 200 may be automatically rotated. Accordingly, the apparatus 1 for preparing an anti-cancer injectate according to the present invention can prevent contamination of the syringe by preventing the syringe necessary for each operation from being mixed, thereby preventing delay in the preparation of the anti-cancer injection agent.

The apparatus 1 for preparing an anti-cancer injectate according to the present invention may further include an electronic scale 7.

The electronic balance 7 is for checking the weight of the anticancer agent and the solution contained in the mixing vessel 130. The electronic scales 7 may be installed in the dispenser 5. Specifically, the electronic scale 7 may be installed in a carry-out unit 4 connected to the preparation unit 5. The electronic balance 7 may be installed between the take-out unit 4 and the dispenser 5. In this case, the electronic balance 7 can be coupled to the article transverse moving member 513. The electronic balance 7 checks the weight of the chemotherapeutic injector contained in the mixing container 130 and controls the weight of the article carrying member 100 such that the article container 100 including the chemotherapeutic injector is carried out by the carry- 512) and the carry-out part (4). The electronic balance 7 can be moved to another position by being rotated while being coupled to the article sideways moving member 513. [ The electronic balance 7 is supported by the article supporting member 511 and supports the article container 100 moved in the descending direction DD by the article carrying member 512 so that the article container 100, The total weight of the fuel cell 100 can be measured. The electronic balance 7 subtracts the weight of the anticancer agent vial 110, the infusion container 120, the mixing container 130, and the container from the total weight of the article container 100, The weight of the injected chemotherapeutic agent can be confirmed. The electronic balance 7 can provide the information input unit 8 with a weight of the confirmed cancer injection. The electronic balance 7 is connected to the information input unit 8 through at least one of wire communication and wireless communication, thereby providing weight information of the anti-cancer injecting agent.

The apparatus for preparing an anti-cancer injectate (1) according to the present invention may further include an information input unit (8).

The information input unit 8 inputs prescription information describing the components of the anticancer drug, and inputs information about the components of the prepared anticancer drug, and stores the data. The information input unit 8 may include a barcode reader 81 and a touch screen 82. The bar code reader 81 and the touch screen 82 may be installed on a lower frame supporting the article sideways moving member 513. The lower frame may be installed on the table 23.

The barcode reader 81 reads out prescription information transmitted from the barcode label attached to the article container 100 through interfacing with the hospital computer network and the kind and weight of the anticancer agent, It is for reading information. The bar code label may be attached to the article container 100 by a dispenser located outside the aseptic dispenser. The barcode label may include information displayed on the touch screen 82.

The touch screen 82 displays and stores information inputted through the barcode reader 81, prepares an anti-cancer injection agent, and transmits information to the hospital computer network. The touch screen 82 includes an information processing and arithmetic unit as well as a display function for displaying information, for example, an integrated computer. When a prescription of the patient is issued in the outpatient clinic and the ward, the prescription information is transmitted to the touch screen 82 through the hospital network, and the dispenser confirms the prescription information and outputs a barcode label to display a barcode A label is attached to the article container 100. Further, the result information on the composition of the anticancer injection preparation is displayed on the touch screen 82 in the mixing container 130 in which the anticancer drug and the solution are mixed, and the dispenser outputs the information on the ingredients of the anticancer injection drug to the barcode, 130). Next, the information on the composition of the anticancer injection preparation is read through the barcode reader 81, and the data is stored in the touch screen 82. The data stored in the touch screen 82 may be transmitted to the hospital network. Accordingly, the preparations for preparing an anticancer injection according to the present invention (1) can compare the prescription information and the preparation information of the anticancer injection preparation, and can store the anticancer injection preparation history for each patient as data. Accordingly, the apparatus 1 for preparing an anticancer injection according to the present invention inputs and outputs prescription information and anticancer injection preparation information for a patient to a barcode, and stores the data as data. Thus, accurate prescribing and dispensing .

It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit or scope of the invention. Will be clear to those who have knowledge of.

1: Preparations for injection of anticancer drugs
2: aseptic preparation 21: support
22: dispensing room 23: table
3: Supply part 4:
5: Preparation part 51: Goods container mechanism
511: article supporting member 512: article elevating member
513: article left-right moving member 52:
521: syringe holding member 522: syringe forward and backward moving member
523: syringe moving member 524: syringe rotating member
525: Syringe lift member 526: Syringe piston moving member
6: Syringe container rotating part 7: Electronic scales
8: Information input unit 81: Barcode reader
82: Touch screen

Claims (12)

An aseptic dispenser provided in a sterile room and provided with a dispenser for preparing an anticancer injection;
A sterilizing tank for supplying the sterilizing agent to the article container including a plurality of anticancer agent vials connected to the aseptic preparation stand and containing the anticancer agent, a liquid container containing the liquid mixed with the anticancer agent, and a mixing container for mixing the anticancer agent and the liquid solution, ;
A preparation unit for extracting the anticancer agent and the liquid solution supplied from the supply unit using a syringe and injecting the same into the mixing container to prepare an anticancer injection; And
And a take-out unit connected to the aseptic preparation stand and configured to take out the article container including the anti-cancer injectable preparation prepared in the preparation unit from the aseptic preparation. The method according to claim 1,
Wherein the supply part and the carry-out part are a conveyer for supporting and transporting the article container. The method according to claim 1,
Wherein the dispenser comprises an article container mechanism for moving the article container, and a syringe mechanism for moving the syringe,
Wherein the syringe mechanism grips and moves one syringe from a syringe container to which a plurality of syringes are detachably coupled. The method of claim 3,
Wherein the article container mechanism comprises:
An article support member for supporting the article container supplied from the supply unit;
An article elevating member for elevating and descending the article supporting member; And
And an article horizontally moving the article elevating and contracting member. The method of claim 3,
The syringe mechanism comprising:
A syringe gripping member for gripping one syringe from the syringe container;
A syringe longitudinal movement member for moving the syringe holding member in a forward direction from the outside to the inside of the aseptic preparation unit and a backward direction opposite to the forward direction;
A syringe left and right movable member movably coupled to the syringe forward and backward moving member and for moving the syringe holding member in a lateral direction;
A syringe rotating member rotatably coupled to the syringe moving member for rotating the syringe holding member such that the syringe is arranged in a vertical row in any one of the anticancer vial, the infusion container, and the mixing container;
A syringe lifting member coupled to the syringe rotating member and lifting the syringe holding member; And
And a syringe piston moving member movably coupled to the syringe elevating member for moving the piston of the syringe. The method of claim 3,
Wherein the article container mechanism and the syringe mechanism each move the article container and the syringe such that the article container and the syringe are positioned at a preparation position for preparing the anti-cancer injection agent. 5. The method of claim 4,
Wherein the article container mechanism comprises a support position for supporting the article container supplied from the supply section by the article supporting member, a preparation position for preparing the anticancer injection agent, and a take-out position for taking out the anti- And the article support member is moved so that the article support member is positioned at each of the plurality of support members. 6. The method of claim 5,
Wherein the syringe mechanism moves the syringe holding member such that the syringe holding member is positioned at a gripping position for gripping one syringe from the syringe container and at a dispensing position for preparing the anticancer injection agent, Dispenser. 6. The method of claim 5,
And a syringe container rotating unit rotating the syringe container to selectively hold one of a plurality of syringes coupled to the syringe container. The method according to claim 1,
Wherein the preparation unit is further provided with an antitumor agent accommodated in the mixing vessel and an electronic balance for checking the weight of the infusion solution. The method according to claim 1,
Further comprising an information input unit for inputting prescription information describing the components of the anticancer drug, and for inputting information on the components of the prepared anticancer drug and storing the data as data. 12. The method of claim 11,
Wherein the information input unit comprises:
A barcode reader for reading prescription information transmitted from a barcode label attached to the article container through interfacing with a hospital network and article information included in the article container; And
And a touch screen for displaying and storing information inputted through the barcode reader, preparing a cancer drug, and transmitting information to a hospital computer network.

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