KR20170126018A - 암 치료 - Google Patents

암 치료 Download PDF

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Publication number
KR20170126018A
KR20170126018A KR1020177032020A KR20177032020A KR20170126018A KR 20170126018 A KR20170126018 A KR 20170126018A KR 1020177032020 A KR1020177032020 A KR 1020177032020A KR 20177032020 A KR20177032020 A KR 20177032020A KR 20170126018 A KR20170126018 A KR 20170126018A
Authority
KR
South Korea
Prior art keywords
cancer
aurka
day
tsa
effective amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020177032020A
Other languages
English (en)
Korean (ko)
Inventor
미하엘 에이치. 폴리메로포울로스
루이스 윌리엄 리카멜레
크리스티안 라베단
Original Assignee
반다 파마슈티칼즈, 인코퍼레이티드.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 반다 파마슈티칼즈, 인코퍼레이티드. filed Critical 반다 파마슈티칼즈, 인코퍼레이티드.
Priority to KR1020217002758A priority Critical patent/KR102315528B1/ko
Publication of KR20170126018A publication Critical patent/KR20170126018A/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020177032020A 2013-08-22 2014-08-22 암 치료 Ceased KR20170126018A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020217002758A KR102315528B1 (ko) 2013-08-22 2014-08-22 암 치료

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361869039P 2013-08-22 2013-08-22
US61/869,039 2013-08-22
PCT/US2014/052209 WO2015027121A2 (en) 2013-08-22 2014-08-22 Cancer treatment

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020167004630A Division KR20160033779A (ko) 2013-08-22 2014-08-22 암 치료

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020217002758A Division KR102315528B1 (ko) 2013-08-22 2014-08-22 암 치료

Publications (1)

Publication Number Publication Date
KR20170126018A true KR20170126018A (ko) 2017-11-15

Family

ID=51794948

Family Applications (5)

Application Number Title Priority Date Filing Date
KR1020177032020A Ceased KR20170126018A (ko) 2013-08-22 2014-08-22 암 치료
KR1020217002758A Active KR102315528B1 (ko) 2013-08-22 2014-08-22 암 치료
KR1020167004630A Ceased KR20160033779A (ko) 2013-08-22 2014-08-22 암 치료
KR1020237010047A Abandoned KR20230047203A (ko) 2013-08-22 2014-08-22 암 치료
KR1020217033186A Ceased KR20210127821A (ko) 2013-08-22 2014-08-22 암 치료

Family Applications After (4)

Application Number Title Priority Date Filing Date
KR1020217002758A Active KR102315528B1 (ko) 2013-08-22 2014-08-22 암 치료
KR1020167004630A Ceased KR20160033779A (ko) 2013-08-22 2014-08-22 암 치료
KR1020237010047A Abandoned KR20230047203A (ko) 2013-08-22 2014-08-22 암 치료
KR1020217033186A Ceased KR20210127821A (ko) 2013-08-22 2014-08-22 암 치료

Country Status (12)

Country Link
US (5) US20160199323A1 (https=)
EP (2) EP3616754A1 (https=)
JP (4) JP2016528297A (https=)
KR (5) KR20170126018A (https=)
CN (2) CN105579101A (https=)
AU (4) AU2014308700A1 (https=)
CA (1) CA2921036A1 (https=)
CL (1) CL2016000397A1 (https=)
EA (1) EA037667B1 (https=)
ES (1) ES2755983T3 (https=)
MX (1) MX381429B (https=)
WO (1) WO2015027121A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210021602A (ko) * 2013-08-22 2021-02-26 반다 파마슈티칼즈, 인코퍼레이티드. 다발성 골수종 치료
EP3616754A1 (en) * 2013-08-22 2020-03-04 Vanda Pharmaceuticals Inc. Cancer treatment
WO2021016203A1 (en) * 2019-07-19 2021-01-28 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Pdlim2 as a biomarker for cancer and as an anti-cancer treatment target
WO2023168201A1 (en) * 2022-03-01 2023-09-07 Vanda Pharmaceuticals Inc. Trichostatin a (tsa) sensitivity in the treatment of tumors

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4218478A (en) * 1979-01-05 1980-08-19 Ruiko Oiwa Trichostatin as an antiprotozoal agent
CA1265431A (en) 1985-01-08 1990-02-06 Roderick John Macdonald Electrode device for flare stack ignitor
JPS61176523A (ja) 1985-01-30 1986-08-08 Teruhiko Beppu 制癌剤
US20020183388A1 (en) 2001-02-01 2002-12-05 Gudas Lorraine J. Use of retinoids plus histone deacetylase inhibitors to inhibit the growth of solid tumors
SI2238982T1 (sl) * 2003-06-27 2013-01-31 Astellas Pharma Inc. Terapevtsko sredstvo za mehkotkivni sarkom
CA2567350C (en) 2004-05-21 2018-06-12 John D. Shaughnessy Use of gene expression profiling to predict survival in cancer patient
GB0519405D0 (en) 2005-09-23 2005-11-02 Univ Aberdeen Cancer therapy prognosis and target
WO2007067516A2 (en) * 2005-12-06 2007-06-14 Duke University Multiple myeloma
CA2652888A1 (en) 2006-05-26 2007-12-06 Celgene Corporation Methods and compositions using immunomodulatory compounds in combination therapy
CA2574531C (en) * 2007-01-19 2016-10-25 The University Of British Columbia Hat acetylation promoters and uses of compositions thereof in promoting immunogenicity
US20110301055A1 (en) 2008-12-05 2011-12-08 Nicholas James Dickens Methods for determining a prognosis in multiple myeloma
US20120107304A1 (en) 2010-04-27 2012-05-03 Boehringer Ingelheim International Gmbh Combination therapy in treatment of oncological and fibrotic diseases
WO2013071247A1 (en) * 2011-11-10 2013-05-16 The United States Of America, As Represented By The Secretary, Department Of Health And Human Servic Gene expression signatures of neoplasm responsiveness to theraphy
EP2602330A1 (en) 2011-12-07 2013-06-12 Palacky University, Olomouc Method of determination of cancer cell drug sensitivity towards Aurora kinase inhibitors and overcoming their resistance
KR20210033067A (ko) * 2012-06-04 2021-03-25 파마싸이클릭스 엘엘씨 브루톤 타이로신 키나아제 저해제의 결정 형태
EP3616754A1 (en) * 2013-08-22 2020-03-04 Vanda Pharmaceuticals Inc. Cancer treatment
KR20210021602A (ko) 2013-08-22 2021-02-26 반다 파마슈티칼즈, 인코퍼레이티드. 다발성 골수종 치료
DE102014117278A1 (de) 2014-11-25 2016-05-25 Krones Ag Hubeinheit zum Anheben und Absenken eines Behälters in einer Behälterbehandlungsanlage

Also Published As

Publication number Publication date
KR20210127821A (ko) 2021-10-22
MX2016002307A (es) 2016-06-15
EP3616754A1 (en) 2020-03-04
JP2019167351A (ja) 2019-10-03
KR20160033779A (ko) 2016-03-28
JP2016528297A (ja) 2016-09-15
AU2021261882B2 (en) 2022-04-14
EP3036007B1 (en) 2019-10-09
JP2023088996A (ja) 2023-06-27
KR20230047203A (ko) 2023-04-06
JP2021105005A (ja) 2021-07-26
AU2019261718A1 (en) 2019-11-28
AU2021261882A1 (en) 2021-12-02
US11667718B2 (en) 2023-06-06
EA201690445A1 (ru) 2016-06-30
US20180256522A1 (en) 2018-09-13
US11078289B2 (en) 2021-08-03
CN110585184A (zh) 2019-12-20
US12590162B2 (en) 2026-03-31
CL2016000397A1 (es) 2017-03-17
EP3036007A2 (en) 2016-06-29
WO2015027121A2 (en) 2015-02-26
US20230257471A1 (en) 2023-08-17
AU2022202183B2 (en) 2023-09-28
MX381429B (es) 2025-03-12
US20210324093A1 (en) 2021-10-21
KR20210013343A (ko) 2021-02-03
WO2015027121A3 (en) 2015-05-14
CA2921036A1 (en) 2015-02-26
NZ716668A (en) 2021-02-26
CN105579101A (zh) 2016-05-11
EA037667B1 (ru) 2021-04-28
AU2014308700A1 (en) 2016-02-25
KR102315528B1 (ko) 2021-10-21
US20160199323A1 (en) 2016-07-14
US10265282B2 (en) 2019-04-23
ES2755983T3 (es) 2020-04-24
US20190211107A1 (en) 2019-07-11
AU2022202183A1 (en) 2022-04-21

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Legal Events

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A107 Divisional application of patent
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Comment text: Divisional Application for International Patent

Patent event code: PA01041R01D

Patent event date: 20171103

Application number text: 1020167004630

Filing date: 20160223

PG1501 Laying open of application
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Patent event date: 20190822

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AMND Amendment
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PE0601 Decision on rejection of patent

Patent event date: 20201028

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Patent event date: 20190902

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