KR20170062135A - Emulsion type cosmetic composition comprising polar organic solvent - Google Patents

Abstract

The present invention relates to an emollient cosmetic composition comprising an amphiphilic anisotropic powder and a polar organic solvent, wherein the amphiphilic anisotropic powder comprises a first polymeric spheroid which is hydrophilic and a second polymeric spheroid which is hydrophobic, Wherein the first polymeric spheroids have a core-shell structure and the shell comprises a functional group, wherein the first polymeric spheroid has a core-shell structure and the second polymeric spheroid at least partially binds to a structure that penetrates the opposite polymeric sphereoid .

Description

[0001] The present invention relates to an emulsion cosmetic composition comprising a polar organic solvent,

The present invention relates to an emulsified cosmetic composition comprising a polar organic solvent and a process for producing the same.

A cosmetic formulation containing a high content of ethanol can be used for cosmetics intended for consumers who are seeking freshness because they can give a feeling of cool feeling and a cooling feeling. Cosmetics containing such ethanol in a high content are generally prepared in the form of a skin, and skin moisturizing power may not be sufficient due to the nature of the skin formulation.

Formulation of emulsifying cosmetic composition can give moisture to skin with flexible feeling. The surfactant usually used for emulsification exhibits a dynamic emulsification state in which the emulsified particles circulate at the emulsified interface after emulsification. When added to the emulsion cosmetics, the ethanol has a large volume swelling due to the temperature rise, and may affect the emulsion stability of the surfactant by affecting the emulsion interface.

The size and shape of the spherical fine particles made of the polymer are controlled according to the manufacturing method, and thus the application possibility is expanded. One of its applications is Pickering emulsion which can form stabilized macroporous particles using micro spherical particles. O / W emulsified particles are formed at a contact angle of 90 ° or more, and W / O emulsion particles are formed at a temperature of 90 ° or less depending on the degree of hydrophilicity / hydrophobicity of the spherical particles.

Attempts have been made to produce new anisotropic powders by imparting amphiphilic properties, both hydrophilic and hydrophobic, to the microspheres. An example is the Janus spherical particles. However, due to the morphological limitations of these spheres, there is a limit to the chemical anisotropy. In other words, although it is morphologically anisotropic, it is totally hydrophobic or hydrophilic, so that there is a limit to chemical anisotropy.

It has been attempted to produce anisotropic powders having surface activity by imparting chemical anisotropy together with geometric shape control. However, despite the advantage of its applicability of amphiphilic anisotropic powder, up to now, Has not been specifically developed, and there is a problem that it is difficult to mass-produce uniformly in the industry, so that no practical industrial application has been made.

The prior art of the present invention is disclosed in Korean Patent Publication No. 1997-0025588.

In view of the above, a problem to be solved by the present invention is to provide an emulsified cosmetic composition containing ethanol and having excellent emulsion stability.

From another point of view, a problem to be solved by the present invention is to provide an emulsified cosmetic composition containing a high amount of ethanol and having excellent emulsion stability.

From another point of view, a problem to be solved by the present invention is to provide a cosmetic composition for emulsifying light feeling.

In another aspect, a problem to be solved by the present invention is to provide a cosmetic composition for emulsifying which can impart a flexible feeling and a pleasant feeling at the same time.

In another aspect, a problem to be solved by the present invention is to provide a cosmetic composition which is excellent in moisture retention and can provide a cooling feeling.

From another viewpoint, a problem to be solved by the present invention is to provide a cosmetic for emulsifying cosmetics having low viscosity and flowability and excellent stability.

In one aspect, the present invention is an emulsified cosmetic composition comprising an amphiphilic anisotropic powder and a polar organic solvent,

The amphiphilic anisotropic powder may be an amorphous powder,

A first polymeric spheroid that is hydrophilic and a second polymeric spheroid that is hydrophobic,

Wherein the first polymeric spheroids and the second polymeric spheroids are at least partially bound to a structure that penetrates the counterpart polymeric spheroids,

Wherein the first polymer spolide has a core-shell structure and the shell comprises a functional group.

In view of the above, a problem to be solved by the present invention is to provide an emulsifying cosmetic composition containing a polar organic solvent and having excellent emulsion stability.

From another point of view, the present invention can provide a cosmetic composition which is excellent in emulsion stability while containing a high content of a polar organic solvent.

From another point of view, the present invention can provide an emulsifying cosmetic material having a light feeling.

From another point of view, the present invention can provide a cosmetic composition for emulsifying which can impart a flexible feeling and a pleasant feeling at the same time.

From another point of view, the present invention can provide a cosmetic preparation for emulsification which is excellent in moisture retention and can provide a cooling feeling.

From another point of view, the present invention can provide a cosmetic composition having excellent flow stability and low viscosity.

Fig. 1 is a photograph of the appearance of the formulation after storing the composition of Example 1 and Comparative Example 1 at 60 캜 for 14 days.
2 is a graph showing changes in viscosity of the compositions of Example 1 and Comparative Example 1 at 30 ° C for 4 weeks.
Fig. 3 is an optical microscope photograph of the emulsion particles at 30 deg. C of the composition of Example 1 and Comparative Example 1. Fig.

Embodiments of the present application will now be described in more detail with reference to the accompanying drawings. However, the techniques disclosed in the present application are not limited to the embodiments described herein but may be embodied in other forms. It should be understood, however, that the embodiments disclosed herein are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art. In the drawings, the widths and thicknesses of components are slightly enlarged in order to clearly illustrate each component. In addition, although only a part of the components is shown for convenience of explanation, those skilled in the art can easily grasp the rest of the components. It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit and scope of the invention.

As used herein, unless otherwise defined, at least one hydrogen atom of the functional groups of the invention is optionally substituted with at least one substituent selected from the group consisting of halogen (F, Cl, Br or I), a hydroxy group, a nitro group, an imino group A substituted or unsubstituted alkyl group having 1 to 20 carbon atoms, a substituted or unsubstituted heteroaryl group having 3 to 30 carbon atoms, a substituted or unsubstituted alkyl group having 1 to 20 carbon atoms, May be substituted with a substituted heterocycloalkyl group having 2-30 carbon atoms.

As used herein, "(meth) acrylic" may mean acryl and / or methacryl.

The particle size of the amphiphilic anisotropic powder herein is the maximum length measured as the longest length of the powder particle. The particle size range of the amphipathic powder herein means that at least 95% of the amphipathic anisotropic powder present in the composition falls within this range.

In the present specification, the average particle diameter of the emulsified particles means an average value of the diameter of the single particles. In the present specification, the mean particle size range of the emulsified particles means that at least 95% of the emulsified particles present in the composition fall within the above range.

According to one embodiment of the present invention, there is provided an emulsified cosmetic composition comprising an amphiphilic anisotropic powder and a polar organic solvent.

In the present embodiment, the polar organic solvent may impart a refreshing sensation and a cooling sensation to the composition. For example, ethanol, acetic acid, and dimethyl amide may be used, but the present invention is not limited thereto. In one example, the polar organic solvent may be ethanol.

The polar organic solvent may be contained in an amount of 0.0001% by weight to 70% by weight, for example, 10% by weight to 50% by weight, based on the total weight of the composition. For example, the polar organic solvent may be used in an amount of at least 0.0001 wt%, at least 0.001 wt%, at least 0.01 wt%, at least 0.05 wt%, at least 0.1 wt%, at least 0.2 wt%, at least 0.3 wt% At least 0.5 wt.%, At least 0.6 wt.%, At least 0.7 wt.%, At least 0.8 wt.%, At least 0.9 wt.%, At least 1 wt.%, At least 2 wt.%, At least 3 wt. Or more, 6% or more, 7% or more, 8% or more, 9% or more, 10% or more, 11% or more, 12% or more, 13% or more, 14% Or more, 16% or more, 17% or more, 18% or more, 19% or more, 20% or more, 21% or more, 22% or more, 23% or more, 24% At least 26 wt%, at least 27 wt%, at least 28 wt%, at least 29 wt%, or at least 30 wt%, and at least 70 wt%, at least 69 wt%, at least 68 wt%, at least 67 wt% Or less, 65 wt% or less, 64 wt% or less, 60% or less, 59% or less, 58% or less, 57% or less, 56% or less, 55% or less, 54% or less, At most 53% by weight, at most 52% by weight, at most 51% by weight, at most 50% by weight, at most 49% by weight, at most 48% by weight, at most 47% by weight, at most 46% 43 wt% or less, 42 wt% or less, 41 wt% or less, 40 wt% or less, 39 wt% or less, 38 wt% or less, 37 wt% or less, 36 wt% or less, 35 wt% 33 wt% or less, 32 wt% or less, 31 wt% or less, or 30 wt% or less. Within this range, a skin feeling and cooling feeling can be imparted with excellent skin safety.

According to this embodiment, it is possible to provide an emulsified composition capable of maintaining emulsion safety even when containing a polar organic solvent in an amount of 10 wt% or more, 15 wt% or more, or 20 wt% or more.

In the present embodiment, the amphiphilic anisotropic powder comprises a first polymeric spheroid which is hydrophilic and a second polymeric spheroid which is hydrophobic, and wherein the first polymeric spheroid and the second polymeric spheroid comprise at least partly spherical polymeric spheroids And the first polymer spolide has a core-shell structure, and the shell may include a functional group.

In this embodiment, the sphere is a body made of a polymer, for example, a spherical sphere, a globoid or an oval shape, and may have a micro- And may have a long axis length in units or nanometers.

In one embodiment, the core of the first polymer spolide and the second polymer spolide include a vinyl polymer, and the shell of the first polymer spolide may include a copolymer of a vinyl monomer and a monomer containing a functional group.

In one example, the vinyl polymer may be a vinyl aromatic polymer, and may be, for example, polystyrene.

In one example, the vinyl monomer may be vinyl aromatic. In one example, the vinyl monomer may be substituted or unsubstituted styrene.

In one example, the functional group may be a siloxane.

In one embodiment, the functional group-containing monomer may be a siloxane-containing (meth) acrylate, and specifically includes 3- (trimethoxysilyl) propyl acrylate, 3- (trimethoxysilyl) propyl methacrylate, vinyl Triethoxysilane, vinyltrimethoxysilane, or a mixture thereof.

In one embodiment, the shell of the first polymer spolide may additionally include a hydrophilic functional group.

For example, the hydrophilic functional group may be a functional group having a negative or positive charge or a polyethylene glycol (PEG) group, and may be a carboxylic acid group, a sulfonic group, a phosphate group, an amino group, an alkoxy group, an ester group, an acetate group, a polyethylene glycol group, And the like.

In one example, the shell of the first polymer spolide may further include a sugar-containing functional group.

In one embodiment, the functional group containing the sugar is selected from the group consisting of N- {N- (3-triethoxysilylpropyl) aminoethyl} gluconamide, N- (3-triethoxysilylpropyl) - (3-triethoxysilylpropyl) aminoethyl} -oligo-hyaluronamide, and the like.

In one embodiment, the amphiphilic anisotropic powder may have a symmetrical shape, an asymmetric snowman shape, or an asymmetric inverse snowman shape based on the joint where the first polymer spoloid and the second polymer spoloid are combined. The shape of the snowman means that the first and second polymer spheroids having different sizes are combined.

In one example, the amphiphilic anisotropic powder may have a particle size of 100 to 2500 nm. In another aspect, the amphiphilic anisotropic powder may have a particle size of 100 to 1500 nm, 100 to 500 nm, or 200 to 300 nm. Specifically, the amphiphilic anisotropic powder preferably has a particle size of 100 nm or more, 200 nm or more, 300 nm or more, 400 nm or more, 500 nm or more, 600 nm or more, 700 nm or more, 800 nm or more, 900 nm or more, Or less, and 2500 nm or less, 2400 nm or less, 2300 nm or less, 2200 nm or less, 2100 nm or less, 2000 nm or less, 1900 nm or less Less than 1,100 nm, less than 1,100 nm, less than 1,000 nm, less than 900 nm, less than 800 nm, less than 700 nm, 600 nm or less, 500 nm or less, 400 nm or less, 300 nm or less, or 200 nm or less.

In one embodiment, the amphiphilic anisotropic powder may form macroparticulate particles of 2 to 200 mu m. In another aspect, the amphiphilic anisotropic powder may be one that forms macro emulsion particles having a size of 5 to 200 mu m, 10 to 100 mu m, 10 to 50 mu m, or 25 mu m. Specifically, the amphiphilic anisotropic powder may have an average particle size of 2 탆 or more, 5 탆 or more, 10 탆 or more, 15 탆 or more, 20 탆 or more, 25 탆 or more, 30 탆 or more, 40 탆 or more, 50 탆 or more, Not more than 150 탆, not more than 180 탆, not more than 200 탆, not more than 180 탆, not more than 150 탆, not more than 130 탆, not more than 100 탆, not more than 80 탆, not more than 50 탆, not more than 40 탆, not more than 30 탆 Emulsified particles having a diameter of not more than 25 mu m, not more than 20 mu m, not more than 15 mu m, not more than 10 mu m, or not more than 5 mu m can be formed.

The hydrophobic portion and the hydrophilic portion of the amphipathic anisotropic powder have different orientations toward the interface, whereby the macro emulsion particles can be formed. The above-described macro emulsified particles can provide an emulsified formulation having a low viscosity having a soft feel.

While the interface film formed by a general molecular level surfactant forms a dynamic emulsification state, the emulsion particle formed by the amphiphilic anisotropic powder increases the thickness of the interfacial film to several hundreds nm and forms a solid interfacial film . Through the formation of the interfacial film, stability of emulsification is improved and stable emulsified state can be maintained without being affected by the polar organic solvent.

In one embodiment, the composition comprises the amphiphilic anisotropic powder in an amount of, for example, at least 0.1%, at least 0.2%, at least 0.3%, at least 0.4%, at least 0.5%, at least 0.6% , Not less than 0.7 wt%, not less than 0.8 wt%, not less than 0.9 wt%, or not less than 1.0 wt%, not more than 20 wt%, not more than 19 wt%, not more than 18 wt%, not more than 17 wt% 14% or less, 13% or less, 12% or less, 11% or less, 10% or less, 9% or less, 8% or less, 7% or less, 6% % Or less, 4 wt% or less, or 3 wt% or less. For example, the composition may comprise from 0.5% to 10% by weight, for example from 1% to 3%, of the amphipathic anisotropic powder relative to the total weight of the composition. Stable emulsion particles can be formed within the above range, and emulsion particles having an appropriate size can be formed.

In one embodiment, the composition is prepared by mixing the polar organic solvent and the amphiphilic anisotropic powder in a weight ratio of polar organic solvent: amphiphilic anisotropic powder of 1 to 9: 9 to 1, such as 1 to 9: 1, such as 3: 1 Rate. The stable emulsified state can be maintained within the above range without being affected by the polar organic solvent.

The method for producing a cosmetic composition according to an embodiment of the present invention may include preparing the amphiphilic anisotropic powder and emulsifying the oil phase and the water phase using the amphoteric anisotropic powder produced.

In one embodiment of the present invention, the amphiphilic anisotropic powder may be prepared by polymerizing a first monomer to prepare a core of a first polymer spoloid, coating the core of the first polymer spoloid to form a core- And preparing an amphiphilic anisotropic powder in which the second polymer spolide is formed by reacting the first polymer spolide of the core-shell structure with the first monomer.

In one embodiment, the amphiphilic anisotropic powder is prepared by (1) stirring the first monomer and the polymerization initiator to prepare a core of the first polymer spolide; (2) stirring the prepared core of the first polymer spolide with a monomer containing a first monomer, a polymerization initiator and a functional group to prepare a first polymer spolide having a coated core-shell structure; (3) preparing an amphiphilic anisotropic powder in which the second polymer spolide is formed by stirring the first polymer spoloid of the prepared core-shell structure with the second monomer and the polymerization initiator.

In the above steps (1), (2) and (3), stirring may be rotary stirring. It is preferable to rotate and stir because chemical mechanical modification and homogeneous mechanical mixing are required for producing uniform particles. The rotational stirring may be performed in a cylindrical rotating reactor, but the rotational stirring method is not limited thereto.

At this time, the design inside the reactor has a great influence on powder formation. The size and location of the baffles in the cylindrical rotating reactor and the degree of spacing between the impeller and the baffles greatly influence the uniformity of the particles produced. It is desirable to minimize the interval between the blades of the inner wing and the impeller to equalize the convection flow and the strength thereof, and to feed the powder reaction liquid below the wing length and to maintain the impeller rotation speed at a high speed. 200 rpm, and the length to diameter ratio of the reactor may be 1 to 3: 1 to 5, more specifically 10 to 30 cm in diameter and 10 to 50 cm in height. The reactor size can be varied in proportion to the reaction capacity. The material of the cylindrical rotating reactor may be ceramics, glass, etc., and the temperature at the time of stirring is preferably 50 to 90 ° C.

In the cylindrical rotating reactor, the simple rotation method is capable of producing uniform particles, and is a low energy method requiring less energy and maximizing the reaction efficiency, enabling mass production. The conventional tumbling method in which the reactor itself rotates requires high energy and restricts the size of the reactor since the entire reactor must be tilted at a constant angle and rotated at high speed. The amount produced due to reactor size limitations was also limited to small quantities of the order of several hundreds of milligrams to several grams, making them unsuitable for mass production.

In one embodiment, the first monomer and the second monomer may be the same or different, and may be specifically vinyl monomers. The first monomer added in the step (2) is the same as the first monomer used in the step (1), and the polymerization initiator used in each step may be the same or different.

In one example, the vinyl monomer may be vinyl aromatic. In one example, the vinyl monomer may be substituted or unsubstituted styrene.

In one example, the polymerization initiator may be a radical polymerization initiator, specifically, a peroxide type, an azo type, or a mixture thereof. Ammonium persulfate, sodium persulfate and potassium persulfate may also be used.

In one example, in the step (1), the first monomer and the polymerization initiator may be mixed at a weight ratio of 100 to 1000: 1. In another aspect, the first monomer and the polymerization initiator may be mixed in a weight ratio of 100 to 750: 1, or 100 to 500: 1, or 100 to 250: 1.

In another aspect, a stabilizer may be added together with the first monomer and the polymerization initiator in the step (1) to mix the first monomer, the polymerization initiator, and the stabilizer in a weight ratio of 100 to 1000: 1: 0.001 to 5. The powder size and shape are determined according to the first polymer spoil size adjustment in the initial stage (1), and the first polymer spoil size can be adjusted according to the weight ratio of the first monomer, the polymerization initiator, and the stabilizer. In addition, by mixing at the weight ratio within the above range, there is an effect that the uniformity of the anisotropic powder can be increased.

In one example, the stabilizer may be an ionic vinyl monomer, and specifically sodium 4-vinylbenzene sulfonate may be used. Stabilizers prevent swelling of the resulting particles and provide positive or negative charge on the powder surface to electrostatically prevent interactions (bonds) during grain formation.

The weight ratio of the first monomer, the polymerization initiator and the stabilizer is 110 to 130: 1: 1 to 5, specifically 115 to 125: 1: 2 to 4, when the amphiphilic anisotropic powder has a size of 200 to 250 nm. 1 < / RTI > polymer spolide.

When the amphiphilic anisotropic powder has a size of 400 to 450 nm, the weight ratio of the first monomer, the polymerization initiator and the stabilizer is in the range of 225 to 240: 1: 1 to 3, specifically 230 to 235: 1: 1 to 3 , ≪ / RTI > the first polymeric spheroids.

When the amphiphilic anisotropic powder has a size of 1100 to 2500 nm, the first polymer having a weight ratio of the first monomer, the polymerization initiator and the stabilizer is 110 to 130: 1: 0, specifically 115 to 125: 1: 0 ≪ / RTI >

The amphiphilic anisotropic powder having an asymmetric snowman shape is preferably an amorphous powder having a weight ratio of the first monomer, the polymerization initiator and the stabilizer of 100 to 140: 1: 8 to 12, specifically 110 to 130: 1: 9 to 11 Can be prepared from polymeric sphereoids.

The amphiphilic anisotropic powder having an asymmetric reverse snowman shape is preferably an amphipathic powder having a weight ratio of the first monomer, the polymerization initiator and the stabilizer of 100 to 140: 1: 1 to 5, specifically 110 to 130: 1: 2 to 4 1 < / RTI > polymer spolide.

In one embodiment, the monomer containing a functional group in the step (2) may be a siloxane-containing (meth) acrylate. Specific examples thereof include 3- (trimethoxysilyl) propyl acrylate, 3- (trimethoxysilyl) Methacrylate, vinyltriethoxysilane, vinyltrimethoxysilane, or a mixture thereof.

In one embodiment, the monomer containing the first monomer, the polymerization initiator and the functional group in the step (2) may be mixed at a weight ratio of 80 to 98: 0.2 to 1.0: 1 to 20. In another aspect, the first monomer, the polymerization initiator, and the monomer containing the functional group may be mixed at a weight ratio of 160 to 200: 1: 6 to 40. The degree of coating can be controlled according to the weight ratio, and the shape of the amphipathic anisotropic powder is determined according to the degree of coating, and when the weight ratio is adjusted, the coating thickness is increased to about 10 to 30%, specifically about 20% And the coating is too thick, so that the pulverization does not proceed or the pulverization is proceeded well without the problem that the pulverization is too thin. In addition, by mixing at the weight ratio within the above range, there is an effect that the uniformity of the anisotropic powder can be increased.

According to the above step (3), a part of the core of the first polymer spolide is protruded from the one side of the first polymer spolide of the core-shell structure through the shell and the protrusions are grown by the polymer of the second monomer, Can be formed.

For example, in the step (3), the second monomer and the polymerization initiator may be mixed in a weight ratio of 150 to 250: 1. In another aspect, the second monomer and the polymerization initiator may be present in an amount of from 160 to 250: 1, or from 170 to 250: 1, or from 180 to 250: 1, or from 190 to 250: 1, or from 200 to 250: : 1, or 220 to 250: 1, or 230 to 250: 1, or 240 to 250: 1.

In another aspect, the second monomer, the polymerization initiator and the stabilizer may be mixed in a weight ratio of 150: 250: 1: 0.001 to 5 by adding the second monomer and the polymerization initiator together with the stabilizer in the step (3). Specific types of stabilizers are as described above. By mixing at a weight ratio within the above range, uniformity of the anisotropic powder can be enhanced.

In one embodiment, in the step (3), the second monomer content may be 40 to 300 parts by weight when the weight of the first polymer spoil of the core-shell structure is 100 parts by weight. Specifically, when the second monomer content is 40 to 100 parts by weight when the first polymer spoil weight of the core-shell structure is 100 parts by weight, the asymmetric snowman type powder is obtained, and 100 to 150 parts by weight, or 110 to 150 parts by weight, When the weight is in the range of 150 to 300 parts by weight or in the range of 160 to 300 parts by weight, an asymmetric reverse snowman type powder is obtained. In addition, by mixing at the weight ratio within the above range, there is an effect that the uniformity of the anisotropic powder can be increased.

In another embodiment of the present invention, in the production of an amphiphilic anisotropic powder according to an embodiment of the present invention, the step (3) may further include the step of (4) introducing a hydrophilic functional group into the produced anisotropic powder have.

In one embodiment, the hydrophilic functional group in step (4) is not limited thereto, but may be introduced using a silane coupling agent and a reaction control agent.

In one embodiment, the silane coupling agent is selected from the group consisting of (3-aminopropyl) trimethoxysilane, N- [3- (trimethoxysilyl) propyl] ethylenediamine, N- [3- (trimethoxysilyl) (Trimethoxysilyl) propyl] urea and 3 - [(trimethoxysilyl) propyloxy] -1,2 (trimethylsilyl) Propanediol, and specifically may be at least one selected from the group consisting of N- [3- (trimethoxysilyl) propyl] ethylenediamine.

For example, the silane coupling agent may be added in an amount of 35 to 65 parts by weight, for example, 40 to 60 parts by weight based on 100 parts by weight of the anisotropic powder prepared in the step (3). Within this range, hydrophilization can be appropriately performed.

In one example, the reaction modifier may be ammonium hydroxide.

For example, the reaction modifier may be added in an amount of 85 to 115 parts by weight, for example, 90 to 110 parts by weight based on 100 parts by weight of the anisotropic powder prepared in the step (3). Within this range, hydrophilization can be appropriately performed.

In another embodiment of the present invention, in the production of the amphiphilic anisotropic powder according to one embodiment of the present invention, the step (3) is followed by (4) a step of introducing a sugar-containing functional group into the produced anisotropic powder .

In the step (4), the functional group containing sugar is not limited thereto, but may be introduced using a sugar-containing silane coupling agent and a reaction control agent.

According to one exemplary embodiment, the sugar-containing silane coupling agent is selected from the group consisting of N- {N- (3-triethoxysilylpropyl) aminoethyl} gluconamide, N- (3-triethoxysilylpropyl) And N- {N- (3-triethoxysilylpropyl) aminoethyl} -oligo-hyaluronamide.

According to one exemplary embodiment, the reaction modifier may be ammonium hydroxide.

For example, the reaction modifier may be added in an amount of 85 to 115 parts by weight, for example, 90 to 110 parts by weight based on 100 parts by weight of the anisotropic powder prepared in the step (3). The introduction of a sugar-containing functional group within the above range can be suitably performed.

The preparation of the amphiphilic anisotropic powder according to the above method does not use a cross-linking agent, so there is no production entanglement. Thus, the yield is high and uniform, and mass production is easier than the tumbling method using a simple agitation method. In particular, there is an advantage that a nano size of 300 nm or less can be mass-produced in a unit of tens g to several tens of kg.

The composition according to this embodiment can be an underwater type or a water-in-oil type emulsified composition, and can be, for example, an underwater type.

The composition according to this embodiment may have a viscosity of greater than or equal to about 1000 cps, greater than about 1200 cps, greater than about 1300 cps, greater than about 1400 cps, greater than about 1500 cps, greater than about 1600 cps, greater than about 1700 cps, Or more, at least 1900 cps, at least 2000 cps, at least 2100 cps, at least 2200 cps, at least 2300 cps, at least 2400 cps, or at least 2500 cps, and no more than 20,000 cps, no more than 19,000 cps, no more than 18,000 cps, no more than 17,000 cps, no more than 16,000 cps Less than 15000 cps, less than 14000 cps, less than 13000 cps, less than 12000 cps, less than 11000 cps, less than 10,000 cps, less than 8900 cps, less than 8800 cps, less than 8700 cps, less than 8600 cps, less than 8500 cps, less than 8400 cps, 8,300 cps or less, 8,800 cps or less, 8000 cps or less, 7900 cps or less, 7800 cps or less, 7700 cps or less, 7600 cps or less, 7500 cps or less, 7400 cps or less, 7300 cps or less, 7200 cps or less, 7100 cps Less than 7000 cps, less than 6900 cps, less than 6800 cps, less than 6700 cps, less than 6600 cps, less than 6500 cps, less than 6400 cps Less than or equal to 6300 cps, less than or equal to 6200 cps, less than or equal to 6100 cps, or less than or equal to 6000 cps. For example, the viscosity may be 1,000 to 20,000 cps, 1,000 cps to 10,000 cps, 1,500 to 7,000 cps, or 2,000 to 6,000 cps.

The composition according to this embodiment can maintain the stability of the emulsified form without containing any additional thickener or wax even when the polar organic solvent is contained in a high content, Composition can be provided. Even when the solid butter is contained in a high content, it is possible to produce a composition having a low viscosity, for example, from 1,000 cps to 10,000 cps, from 2,000 cps to 8,000 cps, or from 4,000 cps to 7,000 cps. A flowable flexible formulation can be provided within the above range, so that a fresh feeling without feeling of tackiness can be exhibited.

The composition according to the present embodiment can provide a emulsified composition including a polar organic solvent, which is refreshing and can provide feeling for giving a cooling feeling.

The composition according to the present embodiment is excellent in emulsion stability in emulsified formulations, including a polar organic solvent, and can give a feeling of soft feeling as an emulsified composition and a refreshing feel as in a skin formulation at the same time. In particular, even in the presence of a high content of polar organic solvent, there is no influence on the stability and the above-mentioned effects can be exhibited.

The composition according to this embodiment may exhibit aging emulsion stability over a wide temperature range, and the temperature may be, for example, from -10 ° C to 60 ° C.

The composition according to this embodiment can contain a large emulsion particle to provide a soft and soft feel.

The composition according to the present invention can provide a composition having a cooling sensation and a cooling sensation, as well as an excellent moisture and moisturizing power that may be lacking in conventional skin formulations.

The composition according to the present embodiment can be formulated into various formulations such as lotion, emulsion, cream and the like. For example, a men's aftershave that can provide a refreshing sensation and a moisture sensation, but the present invention is not limited thereto.

The cosmetic composition according to embodiments of the present invention may be formulated containing a cosmetically or dermatologically acceptable medium or base. It may be in the form of a suspension, a microemulsion, a microcapsule, a microgranule or an ionic (liposome) and a non-ionic follicular dispersion, or a cream, a skin, a lotion, a powder, an ointment, a spray, May be provided in the form of a stick. It can also be used in the form of a foam or in the form of an aerosol composition further containing a compressed propellant. These compositions may be prepared according to conventional methods in the art.

In addition, the cosmetic composition according to embodiments of the present invention may be in the form of powders, fatty substances, organic solvents, solubilizers, thickeners, gelling agents, softeners, antioxidants, suspending agents, stabilizers, foaming agents, , Water, ionic or nonionic emulsifiers, fillers, sequestering agents, chelating agents, preservatives, vitamins, barrier agents, wetting agents, essential oils, dyes, pigments, hydrophilic or lipophilic active agents, lipid vesicles or cosmetics And any other ingredients used, such as cosmetics or adjuvants commonly used in the field of dermatology. Such adjuvants are introduced in amounts commonly used in the cosmetics or dermatological fields. The cosmetic composition according to the embodiments of the present invention may further contain a skin absorption promoting substance to increase the skin improving effect.

Hereinafter, the present invention will be described in more detail with reference to Examples. It is to be understood by those skilled in the art that these embodiments are merely illustrative of the present invention and that the scope of the present invention is not construed as being limited by these embodiments.

 [Production Examples 1 to 4]

Production Examples 1 to 4 were prepared according to the compositions shown in Table 1 below. Specific methods are described below.

The components used in the following Production Examples are as follows.

MeOH: Methanol cosolvent

KPS: Potassium persulfate (initiator)

SVBS: Sodium vinyl benzene sulfonate (stabilizer)

PS: Polystyrene (polymer bead)

TMSPA: Trimethoxysilyl propylacrylate (functional group)

AIBN: Azobisisobutyronitrile (polymerization initiator)

Manufacturing example  1. Polystyrene (PS) First polymer Speroid  Produce

50 g of styrene as a monomer, 1.0 g of sodium 4-vinylbenzenesulfonate as a stabilizer and 0.5 g of azobisisobutyronitrile (AIBN) as a polymerization initiator were mixed in a water bath at 75 DEG C For 8 hours. The reaction was stirred in a cylindrical rotating reactor. The cylindrical rotating reactor was 11 cm in diameter, 17 cm in height, made of glass, and rotated at a speed of 200 rpm.

Preparation Example 2 Preparation of Coated First Polymer Spheroid of Core-Shell (CS) Structure

(Styrene), 6 g of TMSPA (3- (trimethoxysilyl) propylacrylate) as a monomer, and 0.2 g of azobisisobutyronitrile (AIBN) as a polymerization initiator were added to 300 g of the obtained first polymeric spolide of polystyrene ) Were mixed and reacted at 75 DEG C for 8 hours. The reaction was stirred in a cylindrical rotating reactor.

Manufacturing example  3. Amphipathic  Anisotropy Powder  (DB) manufacturing

40 g of styrene as a monomer, 0.35 g of sodium 4-vinylbenzenesulfonate as a stabilizer, and 0.35 g of azobisisobutyronitrile as a polymerization initiator were added to 240 g of the polystyrene core shell (PS-CS) water dispersion solution obtained as a result of the reaction, And 0.2 g of azobisisobutyronitrile (AIBN) were mixed and heated at 75 캜 for 8 hours. The reaction was stirred in a cylindrical rotating reactor to produce an amphiphilic anisotropic powder.

Manufacturing example  4. Hydrophilized Amphipathic  Anisotropy Powder  Produce

30 g of N- [3- (trimethoxysilyl) propyl] ethylenediamine as a silane coupling agent and 30 g of N- [3- (trimethoxysilyl) propyl] ethylenediamine were added to 600 g of the aqueous dispersion solution of the obtained anisotropic powder, (Ammmonium hydroxide) were mixed and reacted at 25 DEG C for 24 hours to introduce a hydrophilic functional group. The reaction was stirred in a cylindrical rotating reactor to prepare a hydrophilized amphipathic anisotropic powder.

[ Example 1] Preparation of emulsified composition

The underwater type emulsion compositions of Example 1 and Comparative Example 1 were prepared according to the compositions shown in Table 2 below. Example 1 is an emulsified composition prepared using the amphiphilic anisotropic powder produced according to Production Example 3, and Comparative Example 1 is an emulsified composition using a general surfactant.

The sphere components used in the following examples and comparative examples are as follows.

(a) Oil:

Butylene blycol / dicaprylate dicaprate (Dermofeel BGC, SASOL)

Cetyl octanoate (SALACOS 816T, Nisshin OilliO)

Diethoxyethyl succinate (CRODAMOL DES-LQ- (JP), Croda)

Cocos Nicifera oil, RBD Coconut Oil K, Fuji (Singapore) Pte., Ltd.)

(b) Surfactant: glyceryl stearate / phage-100 stearate

(c) Water-dispersed amphoteric anisotropic powder: A solution prepared by dissolving 10% by weight of the amphiphilic anisotropic powder of Production Example 3 in 55% by weight of purified water and 35% by weight of butylene glycol

(d) Silicone oil: decamethyl cyclopentasiloxane (DC 345, Dow Corning)

(e) Ion regulator: disodium ethylenediamine acetic acid (disodium EDTA, E.D.T.A.-2NA, Neod)

(f) polar organic solvent: ethanol

(g) Spices: Deep stones, Fermenich

(e) Increasing agent: polyacrylate-13 & polyisobutene & polysorbate 20 (SEPIPLUS 400, SEPPIC)

Ingredients Comparative Example 1 Example 1 Butylene glycol / dicaprylate dicaprate 0.5 0.5 Cetyl octanoate One One Diethoxyethyl succinate One One Cocos Naci Pera Oil 1.5 1.5 Glyceryl stearate / phage-100 stearate 4 0 Water-dispersed amphiphilic anisotropic powder (10%) 0 10 Decamethylcyclopentasiloxane 6 6 Deionized water 54.25 48.25 Disodium ethylenediamine acetic acid 0.05 0.05 ethanol 30 30 Spices 0.7 0.7 Polyacrylate-13 & Polyisobutene & Polysorbate 20 One One

[ Test Example 1] Evaluation of formulation stability according to time and temperature

The formulation stability of the compositions according to Example 1 and Comparative Example 1 was observed at -5 ° C, 30 ° C, 37 ° C, 45 ° C and 60 ° C for 4 weeks, respectively, and the results are shown in Table 3 below.

Comparative Example 1 Example 1 Comparative Example 1 Example 1 Comparative Example 1 Example 1 Comparative Example 1 Example 1 term 3 days 7 days 14 days 4 weeks Temperature 30 ℃ clear 37 ℃ clear 45 ° C Interlayer stripes and dot generation clear Interlayer stripes and dot generation clear slightly
Phase separation clear Phase separation
Top hardening clear 60 ° C Interlayer stripes and dot generation clear Interlayer stripes and dot generation clear Phase separation clear Phase separation
Top hardening clear -5 ℃ clear

In the results of Table 3, in the case of Comparative Example 1 using a general surfactant, interstellar stripes and dots were generated when stored at 45 ° C and 60 ° C for 3 days to 7 days, phase separation was observed when stored for 14 days, It can be seen that the upper part hardens at the elapsed time while the emulsion stability is maintained for 4 weeks at the wide temperature range in the case of Example 1. [

Fig. 1 is a photograph of the external appearance of the formulation after storing the composition of Comparative Example 1 and Example 1 at 60 占 폚 for 14 days. It can be confirmed that the phase separation was observed in Comparative Example 1, but the appearance of the stable composition in Example 1 was exhibited.

[ Test Example 2] Evaluation of viscosity change with time

The viscosity of the composition according to Example 1 and Comparative Example 1 was measured with a viscometer (LVDV-II + PRO, BROOKFIELD, USA) over a period of 4 weeks at 30 ° C., Respectively.

2, the initial viscosity of Comparative Example 1 was very high, showing a large change which markedly decreased on the first week and increased with time thereafter. On the other hand, in Example 1, It can be confirmed that the viscosity is kept stable with almost no change in viscosity.

[ Test Example 3] Evaluation of emulsion particle stability over time

The composition according to Example 1 and Comparative Example 1 was maintained at 30 캜 for 4 weeks, and emulsion particles were observed with an optical microscope immediately after the preparation and after 4 weeks, and the change with time was confirmed. The results are shown in FIG.

3 shows that in Comparative Example 1, fine emulsion particles were formed immediately after production, but emulsified particles collapsed after four weeks to collapse to emulsify. In Example 1, however, It can be seen that the stability remains stable even after large fluctuations.

[ Test Example 4] Sensory evaluation

45 men of 30 to 50 years old were allowed to use the compositions of Comparative Example 1 and Example 1, and a 5-point scale (1 point: very poor, 2 points: poor, 3 Point: normal, 4 points: excellent, and 5 points: very excellent). The results are shown in Table 4 below.

Refreshing feeling Cooling Moisture Comparative Example 1 3.8 4.2 3.9 Example 1 4.7 4.9 4.1

In the results of Table 4, it can be seen that in Comparative Example 1, the formulation stability is unstable and it is difficult for the formulation itself to be maintained. In Example 1, it is possible to maintain a stable formulation while maintaining a cool sensation, a cooling sensation and a moisture sensation.

Claims (20)

An amphoteric cosmetic composition comprising an amphiphilic anisotropic powder and a polar organic solvent,
The amphiphilic anisotropic powder may be an amorphous powder,
A first polymeric spheroid that is hydrophilic and a second polymeric spheroid that is hydrophobic,
Wherein the first polymeric spheroids and the second polymeric spheroids are at least partially bound to a structure that penetrates the counterpart polymeric spheroids,
Wherein the first polymer spolide has a core-shell structure and the shell comprises a functional group. The method according to claim 1,
Wherein the polar organic solvent is present in an amount of 10% by weight or more based on the total weight of the composition. The method according to claim 1,
Wherein the polar organic solvent is present in an amount of 20% by weight or more based on the total weight of the composition. The method according to claim 1,
Wherein the polar organic solvent is included in an amount of 20% by weight to 70% by weight based on the total weight of the composition. The method according to claim 1,
Wherein the polar organic solvent is at least one selected from the group consisting of ethanol, acetic acid and dimethylacetamide. The method according to claim 1,
Wherein the composition comprises from 1% to 10% by weight of the amphiphilic anisotropic powder relative to the total weight of the composition. The method according to claim 1,
Wherein the composition is an underwater type. The method according to claim 1,
Wherein the composition has a viscosity of 1000 to 20000 cps. The method according to claim 1,
Wherein the functional group is a siloxane. The method according to claim 1,
Wherein the core of the first polymer spolide and the second polymer spolide comprise a vinyl polymer,
The shell of the first polymer spolide may comprise a vinyl monomer; And a monomer containing a functional group. 11. The method of claim 10,
Wherein the vinyl polymer is a vinyl aromatic polymer. 11. The method of claim 10,
Wherein the vinyl monomer is a vinyl aromatic monomer. 11. The method of claim 10,
Wherein the functional group-containing monomer is a siloxane-containing (meth) acrylate. The method according to claim 1,
Wherein the amphipathic anisotropic powder has a symmetrical shape, an asymmetric snowman shape or an asymmetric inverted snowman shape with respect to the joint where the first polymeric spheroid and the second polymeric spheroid are bonded. The method according to claim 1,
Wherein the amphiphilic anisotropic powder has a particle size of 100 to 2500 nm. The method according to claim 1,
Wherein the amphiphilic anisotropic powder forms macroparticulate particles having an average particle size of 2 to 200 탆. The method according to claim 1,
Wherein the shell of the first polymer spolide is further introduced with a hydrophilic functional group. 17. The method of claim 16,
Wherein the hydrophilic functional group is at least one selected from the group consisting of a carboxylic acid group, a sulfonic group, a phosphate group, an amino group, an alkoxy group, an ester group, an acetate group, a polyethylene glycol group and a hydroxyl group. The method according to claim 1,
Wherein the shell of the first polymer spolide is further introduced with a sugar-containing functional group. 20. The method of claim 19,
The functional groups containing the sugar include N- {N- (3-triethoxysilylpropyl) aminoethyl} gluconamide, N- (3-triethoxysilylpropyl) -Triethoxysilylpropyl) aminoethyl} -oligo-hyaluronamide. ≪ / RTI >

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