KR20170000617U - A cell-collection device and a cell-collection assembly - Google Patents

Abstract

The design provides a sort of cell collector, which includes a handle and a circular or polygonal needle collector with a cross section connected thereto. The collection portion includes a base entity and an antibody layer used outside of the base entity for capturing a target cell. The present design provides a sort of cell collection component, which includes a hepatic cap, an activity plug, and a cell collector for liver consumption as described above. The above-mentioned liver consumption includes a main body. At one end of the body there is a rubber horse. The rubber stopper inside the body is connected to the body, and there is a part that connects to the body at the hole of the other body of the body. The above-described cell collector includes a handle portion which is inserted into the above-mentioned rubber stopper, and a cell collecting portion which is connected to one side of the above-described handle and which is fixed in the aforementioned space. The new cell collectors and cell collection components of the present invention are able to identify the deficiencies of current cell collection methods and to advantage in the collection of blood cells.

Description

A cell-collecting device and a cell-

The present invention relates to medical machine technology, particularly to a cell collector and cell collection component.

In the diagnosis or treatment of diseases, human blood cells are often collected and processed for the accurate determination of the cause of disease, pathological culture, and the like. Most of these methods collect blood from a blood sample after taking blood in the human body, and then examine them. Such a cell collection method has a relatively low selectivity for the blood sample and a small blood sample of 5 to 15 ml. Cells in the blood sample easily lose activity, and the collected cells have relatively low confidence. Also, the amount of blood sample is relatively small, and the number of collected cells is relatively small. When the blood is released from the human body, the cell is also easily lost its activity. With these factors, current cell collection methods do not meet the need to diagnose and treat diseases with high efficiency.

In view of this point, the inventor has developed a cell collector capable of easily collecting cells from a blood vessel, and poses a technical problem of presenting a method of collecting cells and a lack of a cell collection component.

The present invention discloses a cell collector. The measuring instrument included a handle portion, a collecting portion fixed to one of the handle portions described above. The cross section of the collecting section described above is circular or polygonal needle-like. The above-described collecting part includes a basic part, an antibody layer used for capturing a target cell outside the above-mentioned basic part.

The above-described cell collector collecting part is a needle-like cylindrical shape.

The outside of the cell collector basic part described above has a metal plating layer and the above-mentioned antibody layer is on the metal plating layer.

A biocompatible polymer layer is provided outside the basic part of the above-described cell collector and the above-mentioned antibody layer is on the bio-compatible polymer layer.

A metal plating layer and a biocompatible polymer layer are sequentially provided outside the basic portion of the above-described cell collector. The above-mentioned antibody layer is on the biocompatible polymer layer.

The basic part of the above-described cell collector is stainless steel, the above-mentioned metal plating layer is a plated layer, and the bio-compatible polymer layer described above is a hydrogel layer.

The aforementioned handle portion of the above-described cell collector has at least one position mark.

The above-described cell collector also includes a headgear, which is located close to the above collecting portion of the above handle portion. The above-described simple model includes a liver-consuming body, a rubber stopper fitted on one side of the above-mentioned liver-consuming body, and an accommodating space formed on the other side of the liver-erasing body connected to the above- mentioned rubber- The above-mentioned handle portion is inserted into the rubber stopper, and the above-mentioned collecting unit is placed in the above-mentioned accommodating space.

In the above-described cell collectors, a headgear for closing the entrance of the above-mentioned accommodating space is provided.

In the headgear of the cell collector described above, a protective space is formed at one of the openings of the headgear and connected to the above-described accommodating space when the above-described headgear is connected to the exhaustion.

This invention discloses a cell collection component that includes the following components: Liver consume, the above mentioned gansoomoe includes the body. On one side of the above-mentioned body, there is a rubber-covered dog. Inside the above-mentioned body, there is a space connected to the aforementioned rubber-covered dog and open on the other side of the aforementioned body. One side of the aforementioned space inlet of the above-mentioned trunk of the liver consuming is provided with a connecting portion for connecting the above-mentioned trunk. The activity plug of the cell collector is in the above-mentioned simple cell. The above-described cell collector includes a handle portion which is inserted into the rubber stopper described above, and a cell collecting portion inside the above-mentioned space. The above-described cell collecting part is fixed to one side of the aforementioned handle part.

The above-described cell collecting part of the above-described cell collecting part includes a basic part, an antibody layer used for capturing a target cell provided outside the above-mentioned basic part.

Above the above-mentioned basic part of the above-mentioned cell collecting part, there is a metal plating layer, and the above-mentioned antibody layer is in the metal plating layer.

The biocompatible polymer layer is provided on the outside of the basic part of the above-mentioned cell collecting part and the above-mentioned antibody layer is on the biocompatible polymer layer.

Externally to the above-mentioned basic parts of the above-described cell collecting parts are a metal plating layer and a biocompatible polymer layer in turn. The above-mentioned antibody layer is on the biocompatible polymer layer.

The basic part of the above-described cell collecting part is stainless steel, the above-described metal plating layer is a plated layer, and the bio-compatible polymer layer described above is a hydrogel layer.

The cross section of the above-mentioned cell collection part of the above-mentioned cell collection part is a circular or polygonal needle-like structure.

The cell collecting part of the above-mentioned cell collecting part is a helical needle-like structure.

There is at least one position mark on the grip portion of the above-mentioned cell collecting part.

There is a recessed hole at one side of the body space inlet of the above-mentioned cell collecting part. In the middle of the above-mentioned hole, there is a columnar object fixed to the body, and the above-mentioned space is connected to the above columnar object and is open at the end of the columnar object described above. The above-mentioned connecting portion is a thread in the recessed pierced hole inner wall described above.

Compared to the current technology, this design has the advantage below.

(1) The cell collector of the present invention was designed by collecting part and handle part, and an antibody layer used for collecting cells was installed in the collecting part. When the collection of blood cells is necessary, the collection part can be collected in the blood vessel by holding the handle part with the needle and putting it into the human blood vessel. As the blood of the blood vessels flows continuously through the collecting part, it can contact more cells as compared with the current blood collecting method, and it is possible to greatly enhance the reliability of cell collection without losing cell activity.

(2) The above-described cell collectors of the present invention are provided with liver consumption, and there is a storage space on the liver consumption, so that the collection part can be protected during the storage process.

(3) A headgear with a protective space installed in the above-described cell collector of the present invention can well protect the collection part with the liver consumed.

(4) The cell collection parts of the present invention connect the needles to the needles when the cells are collected through a cell collector of liver consuming cells, and the cell collection part of the cell collector is pushed into the human blood vessels and the necessary cells are directly collected from the human blood vessels. As blood vessels are constantly passing through the cell collection area, compared with the current blood collection method, the number of contacted cells is greatly increased, the cell activity is not lost, and furthermore, the reliability of cell collection can be greatly improved. It is only necessary to wait for the collection of cells in the cell collection unit after piercing the cell collection unit into the blood vessels of the human body. Therefore, it is possible to reduce the complicated operation of the current blood collection method and collect the cells more conveniently.

(5) In the above-described cell collecting parts of the present invention, the base portion serves as the medium, and the metal plating layer and the biocompatible polymer layer fix the antibody layer that collects the cells. Cell collection part The cylindrical or helical needle-like structure can adapt to the different cell collection demand by varying the amount of the antibody layer.

(6) The above-described cell collecting part of the present invention has a joint portion, which facilitates the consumption of the liver and the connection between the parts. A recessed hole was installed and a thread was attached to the connecting part to connect the small part to the corresponding part, and the overall structure was further woven.

(7) Among the above-described cell collectors and cell collecting parts of the present invention, the basic part is stainless steel, the metal plating layer is a plated layer, the biocompatible polymer layer is a hydrogel layer, and the antibody layer is provided in a collecting part. .

(8) The position of the above-mentioned cell collectors and cell collecting parts of the present invention can be adjusted to control the length of the cell collecting part when the cells are collected.

The drawings of the present invention can help the understanding of the present invention. The demonstration examples and explanations of this invention are only a description of this invention and do not constitute undue restrictions on this invention. In the figure,
FIG. 1 is a schematic view of the above-described cell collector in Example 1 of the present invention; FIG.
Fig. 2 is a local enlarged view of part A in Fig. 1; Fig.
Fig. 3 is a schematic view of the liver consumption described in the first embodiment of the present invention; Fig.
Fig. 4 is a cross-sectional view taken along line BB in Fig. 3;
FIG. 5 is a schematic view showing the combination of the above-described cell collector and liver consuming in Embodiment 1 of the present invention; FIG.
FIG. 6 is a structural view of the above-described headgear in Embodiment 1 of the present invention; FIG.
FIG. 7 is a cross-sectional view of the CC plane in FIG. 6; FIG.
FIG. 8 is a schematic view showing the combination of the cell collector, the liver consuming and the headgear described in Embodiment 1 of the present invention; FIG.
Fig. 9 is a schematic view of the above-described cell collecting part in Example 2 of the present invention; Fig.
10 is a structural view of the cell collector described in Example 2 of the present invention;
11 is a local enlarged view of a portion A in Fig. 10;
Fig. 12 is a schematic view of the liver consuming described in Embodiment 2 of the present invention; Fig.
13 is a cross-sectional view taken along line BB in Fig. 12;
Description of Reference Numerals:
1-collector portion, 2-handle portion, 3-position indicator, 5-liver dissipation, 6-headgear, 11-base portion, 12-metal plating layer, 13-biocompatible polymer layer, 54-pillar-shaped object, 54-pillar-shaped object, 55-recessed pored hole, 56-slanted surface, 57-thread, 58-paired annular stand, 61-headgear body, 62 Cell-collecting part, 211-cell collecting part, 212-handle part, 213-position marking, 221-torso, 222-rubber stopper, 223-subject, 224-space, 225-recessed hole, 226-slope, 227-thread, 228-slippery pattern, 111-base portion, 112-metal plating layer, Layer, 114-antibody layer.

Concrete implementation method

The design is described below in detail by connecting the drawings and examples.

Example 1

This embodiment relates to a cell sorting apparatus and is shown in FIGS. 1 and 2. FIG. Which includes a handle portion 2 and a needle-like collecting portion 1 connected to one side of the handle portion 2. The collection part 2 includes a basic part 11, a metal plating layer 12 outside the basic part 11, a bio-compatible polymer layer 12 and an antibody layer 14 used for capturing a target cell. The antibody layer 14 can be provided on the base portion 11 through the metal plating layer 12 and the bio-compatible polymer layer 12, as well as on the base portion 11 only through the metal plating layer 12 or the biocompatible polymer layer 12.

In the present embodiment, the base portion 11 is made of stainless steel and has a round cylindrical needle-like structure similar to the cross-sectional view in Fig. 1, except for the cylindrical needle-like structure, the base portion 11 has a triangular, rectangular, , A hexagonal shape, or an arbitrary hexagonal shape. In this embodiment, the handle portion 2 is a columnar stainless steel structure, which can follow the cross-sectional shape of the basic portion 11. The handle portion 2 and the base portion 11 of the collecting portion 1 are integrally structured so as to be convenient for manufacturing this cell collector. Of course, except for stainless steel, base 11 and handle 2 can also be made of other materials such as glass fiber or organic polymer vinyl supports. In this embodiment, the metal plating layer 12 outside the basic portion 11 is a plating layer (gold). In addition to the plating layer, the metal plating layer 12 may be made of metal such as nickel, copper, palladium, silver or platinum. The biocompatible polymer layer 12 can use not only a hydrogel layer but also other hydrophilic materials.

The antibody layer 14, which is the first of the examples, is an antigenic antibody having biological activity fixed to the bio-compatible polymer layer 12. This antigen antibody captures a specific cell of the blood, that is, a target cell, for example, a tumor cell, through the immune response when entering the human blood vessel in the collecting part 2. Different antigen antibodies can be employed when different target cells are needed. In this embodiment, as shown in FIG. 1, a two-position indicator 3 is provided on the handle 2 to control the length of the collecting part 1 into the blood vessel when collecting the cells. Of course, based on the demand, the position indicator 3 can design other quantity, for example 1, 3, 4, etc. In order to easily pierce the cell collector, a hydraulic end (not shown) may be provided on the other side of the other handle part 2 of the collecting part 1 in this embodiment. This end may be a hemispherical structure having a handle portion 2 end formed therein, or may have a wide-shaped structure.

In order to conveniently use and store the cell collector in the present embodiment, a liver consumption 5 as shown in Fig. 3 can be provided in the vicinity of the collecting part 1 of the handle part 2. Fig. The concrete structure of liver consumption 5 is as shown in FIG. 3 and FIG. And a rubber stopper 52 provided on one side of the liver-consuming body 51 and the liver-consuming body 51 is included. Inside the trunk lid 51, it is connected to a rubber stopper 52 and on the other side of the trunk lid 51

And an open space 54 is included. The collecting part 1 of the cell collector is provided in this accommodating space 54 and has a connecting part for connecting the liver-consuming body 51 to one side of the entrance of the accommodating space 54 in the liver-

In this embodiment, the liver-consuming body 51 can be injection-molded with vinyl. The rubber stopper 52 is provided at the end of the liver-consuming body 51, and one end of the rubber stopper 52 is at the end of the liver-consuming body 51. In the present embodiment, the rubber stoppers 52 may be made of rubber or silica gel. On the other side of the rubber stopper 52 of the liver-consuming body 51, there is a hole 55 which is recessed and recessed. Hole 55 has a columnar body 53 fixed to the body 51 and extends in the columnar body 53 from the accommodating space 44, that is, the liver-consuming body 51, and the accommodating space 54 is provided at the end of the columnar body 53, Respectively.

In this embodiment, the joint portion of the liver-consuming body 51 is a thread 57 formed on the inner wall of the recessed recessed hole 55. It is possible to use the screw thread 57 to connect the joint 5 and other parts to form a wider overall structure and to conveniently store and use it. In this embodiment, the free end portion of the columnar body 53, that is, the inner side portion of the entrance of the accommodating space 54, and the outer surface cross-section of the columnar body 53 show a conical shape gradually diminishing, as shown in FIG. The outer surface of the columnar shaped body 53 forms a conical surface 56 which can be connected to other parts through the threaded joint 57. In order to prevent the fingers from being stuck when the rubber stopper 52 of the consuming cell collector 5 is inserted, an annular pedestal 58, which is recessed at one side near the rubber stopper 52 outside the liver ending body 51, Respectively. In this case, a conduit not shown in the drawing can be inserted so that the hand is not stuck.

Through the provision of an annularly shaped annular band 58 and a stabbing conduit, the cell collector was located inside the stabbing conduit to prevent the cell collector from accidentally crushing the fingers. As shown in FIG. 3, in the present embodiment, a non-slip pattern is formed on one side close to the entrance of the external accommodating space 54 of the liver-consuming body 51 in order to connect the liver-consuming 5 and other parts conveniently. The structure of the cell collector installed in liver consumption 5 is shown in FIG. After the cell collector is placed on the fifth consume of the liver, various manipulations of the cell collector such as cell collection or storage can be performed. At this time, in order to perform protective storage after putting the cell collector 5 on the liver consuming 5, a head gear which blocks the intake space 54 at the liver consumption 5 in this embodiment can be installed.

The structure of one kind of headgear in this embodiment is as shown in Figs. 6 and 7. Fig. Here, the head gear body 61 is included. In the inside of the headgear body 61, a protection space 62 opened on one side of the headgear body 61 is provided. An external thread 64 for connecting the headgear body 61 to the outer surface of the headgear body 61 is provided on one side close to the entrance of the protective space 62. The headgear 6 is connected to the outer joint 5 through the combination of external thread 64 and thread 57 of thread 5.

In this embodiment, the headgear body 61 has a two-stage structure in which the outer diameter is different. The external thread 64 is a portion of the headgear body 61 that has a relatively small outer diameter. The headgear body 61 can be injection molded with vinyl. In order to connect the headgear 6 and the liver consumable 5 with ease, the protective space 62 in this embodiment is designed to have a conical shape that gradually decreases from the entrance to the inside. The columnar body 53 of the collecting part 1 can be inserted into the protective space 62 relatively easily. In order to reduce the weight of the head gear 6, an annular groove is provided on the other side of the inlet 62 of the protection space 62 of the head gear body 61 in the present embodiment, and an additional screw 65 is provided on the inner wall approaching the outside of the annular groove 63 . By installing the additional thread 65, it is possible to conveniently connect the headgear 6 with other parts and conveniently install the headgear 6.

An annular washer installation groove not shown in the figure can be formed on one side of the entrance of the protection space 62 of the headgear body 61 in this embodiment. A rubber screw receiver can be installed in the washer mounting groove, and the hermeticity of the connection between the head gear 6 and the joint 5 can be improved through the rubber screw receiver. In this embodiment, as shown in Fig. 6, a slip-resistant pattern is formed on the other outer surface of the head gear body 61 relative to the external thread 64. [ This slip prevention pattern is a protrusion structure as shown in Fig. Except for the projecting structure, the non-slipping pattern may have a plurality of lumpy structures or annular structures. The structure in which the head gear 6 is connected to the liver consuming 5 with the cell collector is as shown in Fig. In this case, if the protective liquid is injected into the protective space 62 of the headgear 6, the cell collector collecting unit 1 can be protected for a long period of time.

The headgear 6 can take other structural forms than the above-described structure. For example, one thread can be designed as a simple pillar structure with a hollow spool 5 connected to it. In addition to the above-described structure type, the liver consumption 5 employs other current structure and can be hermetically connected to the headgear 6. In a specific use, the cell collector is installed in the joint 5, the collecting part 1 is inserted into the accommodation space 54, and a protective liquid is injected into the protection space 62 of the headgear 6. The next headgear 6 may be installed in the intermediate consumable 5, and the cell collector collecting unit 1 of the accommodating space 54 may be inserted into the accommodating space 54 and the protecting space 62 to create a closed space. If you want to collect cells with a cell collector, remove the headgear 6, connect the liver consuming 5 with the cell collector to the indwelling needle, and manipulate the handle part 2 to pierce one side of the collection part 1 into the human blood vessel.

Example 2

This embodiment relates to a kind of cell collecting part and is as shown in Fig. This includes a cell collector 101 inserted into liver 102 and liver waste 102. The structure of the cell collector 101 is as shown in FIG. 10 and FIG. The cell collector 101 includes a needle-like cell collecting unit 211 connected to one side of the handle portion 212 and the handle portion 212. The cell collection unit 211 includes a basic portion 111, a metal plating layer 112 outside the basic portion 111, a bio-compatible polymer layer 113, and an antibody layer 114 used for capturing target cells. Of course, the antibody layer 114 can be installed on the basic portion 111 through the metal plating layer 112 and the biocompatible polymer layer 112 as well as on the base portion 111 only through the metal plating layer 112 or the biocompatible polymer layer 112.

In the present embodiment, the base portion 111 employs stainless steel and has a circular cylindrical needle-like structure in cross section as shown in FIG. The base portion 111 may have a polygonal structure such as a triangle, a rectangle, a rhombus, a pentagon, a hexagon, an arbitrary pentagon, or an arbitrary hexagon, and the base portion 111 may have a helical needle shape Structure. In this embodiment, the handle portion 212 is a columnar stainless steel structure, and the handle portion 212 is an integral structure with the base portion 111 of the cell collecting portion 211. This made it convenient for the production of this cell collector 101. Of course, stainless steel can be employed, and the base portion 111 and the handle portion 212 can be made of other materials such as glass fiber or organic polymer vinyl stand. In this embodiment, the metal plating layer 112 outside the base portion 111 is a plating layer (plating layer). Except for the plating layer, the metal plating layer 112 may employ metals such as nickel, copper, palladium, silver, and platinum. The biocompatible polymer layer 113 may employ a hydrogel layer, and other than this layer, the biocompatible polymer layer 113 may employ other hydrophilic materials.

The antibody layer 114, which is the outermost one in the present embodiment, is an antigenic antibody having biological activity fixed to the bio-compatible polymer layer 113. When the cell collection unit 211 enters the human blood vessel, the antigen antibody can capture necessary target cells such as specific cells of the blood, that is, tumor cells through an immune response. If different target cells need to be collected, different antigen antibodies can be employed. As shown in FIG. 10 of the present embodiment, two position marks 213 are provided on the handle portion 212 to control the length of the cell collecting portion 211 into the blood vessel when the cells are collected. Of course, in addition to installing two, the location indicator 213 can design one or three or four other quantities based on demand. In order to conveniently manipulate the cell collector 101, a hand pressure end not shown in the drawing may be provided on the other side of the handle portion 212 of the present embodiment, which is opposite to the cell collecting portion 211. This end may be a hemispherical structure or a wide-shaped structure.

The structure of the inter-consumable 102 in this embodiment is as shown in Figs. 12 and 13. Fig. Here, a body 221 is included, and a rubber stopper 222 is provided on one side of the body 221. The body 221 includes a space 224 connected to the rubber stopper 222 and opened on the other side of the body 221, and a connecting portion connecting the body 221 to one of the openings of the space 224 of the body 221. The cell collector 101 is plugged into a rubber stopper 222 and places the cell collecting unit 211 in the space 224.

In this embodiment, the body 221 can be injection molded by vinyl. The rubber stopper 222 is provided at the end of the body 221 and the other end of the rubber stopper 222 is at the end of the body 221. In the present embodiment, the rubber stoppers 222 may be made of rubber or silica gel. On the other side of the body 221 corresponding to the rubber stopper 222, there is provided a recessed recess 225, and a recessed recess 225 is provided with a columnar object 223 provided on the body 221. The space 224 extends from the body 221 to the inside of the columnar object 223, and the space 224 is at the entrance of the end of the columnar object 223.

In the present embodiment, the connecting portion provided on the body 221 is a thread 227 formed on the inner wall of the recessed recess 225. The use of thread 227 allows a relatively well-woven structure to be built and convenient to store and use after connecting the consumable 102 and other components. Of course, except for threads 227, the connecting part may be an external thread external to the body 221. In this case, it is possible to provide a hollow 225 and a columnar object 223 which are recessed and recessed in the body 221. Alternatively, the space 224 may pass through the body 221 and be opened at the end of the body 221 without providing a recess 225 in the body 221. In this embodiment, the free portion of the columnar object 223 faces inward at the entrance of the space 224 and the outer surface of the columnar object 223 forms a conical surface in which the cross section gradually decreases. At this time, as shown in Fig. The outer surface of the columnar object 223 forms a conical surface 226. With the design of the conical surface 226, the liver consumable 102 can be connected to other components through the thread 227.

A finger may be stuck when the rubber stopper 222 is inserted into the liver consumable 102 of the cell collector 101. In this embodiment, a protruding plate (not shown) can be formed on one side of the body 221 that approaches the rubber stopper 222 on the outer surface. This stone substrate blocks the fingers and prevents the cell collector 101 from inadvertently sticking the finger. The stone substrate can be formed in a ring shape or in a plurality of planar structures provided at regular intervals. 12, a slip prevention pattern 228 is formed on one side of the entrance near the space 224 on the outer surface of the body 221 in order to connect the liver consuming 102 and other components (for example, the immersion needle). The anti-slip pattern 228 can be formed as a protrusion structure shown in Fig. Of course, other than the protruding structure, the non-slippery pattern 228 may adopt other structure types such as a plurality of protrusion-like structures or a plurality of annular protrusions.

When the present cell collecting part is used, the liver consuming 102 is connected to the indwelling needle in the human blood vessel through the thread 227 and the cell collecting part 211 can be put into the human blood vessel by manipulating the handle part 212. The antibody layer 114 of the cell collecting part 21 So that the target cells can be collected. When the cell collecting part is not used, an object having an inlet and a space may be covered with a consumable part 102 of the thread 227 to seal the space 224 with the cell collecting part 211. Thereby protecting the cell collection unit 211 and protecting the cell collection parts.

The above is merely a comparatively good use of the new measuring instrument for practical use and does not limit the use of the new measuring instrument for practical use. Any amendments, equivalence replacements, and advances made in the scope of the spirit and principle of this new practical measuring instrument are all within the scope of protection of this new type of measuring instrument.

Claims (20)

In a kind of cell collector including a handle portion,
And a collecting portion fixed to one end of the handle portion, wherein the cross section of the collecting portion is circular or polygonal needle-like, and the collecting portion includes a base portion and an antibody layer used for capturing a target cell attached outside the base portion Features a cell collector. The cell collector according to claim 1, wherein the collecting portion is a cylindrical needle-like shape. The cell collector according to claim 1 or 2, wherein a metal plating layer is present outside the base portion, and the antibody layer is in a metal plating layer. 3. The cell collector of claim 1 or 2, wherein a biocompatible polymer layer is present outside the base portion and the antibody layer is above a biocompatible polymer layer. 3. The cell collector of claim 1 or 2, wherein a metal plating layer and a bio-compatible polymer layer are sequentially formed on the outside of the base portion, and the antibody layer is on the bio-compatible polymer layer. 6. The cell collector of claim 5, wherein the base portion is stainless steel, the metal plating layer is a plated layer, and the biocompatible polymer layer is a hydrogel layer. The cell collector of claim 1, wherein the handle portion has at least one position mark. 2. The apparatus according to claim 1, wherein an active cover is provided in a simple shape close to the collecting portion side of the handle portion, and the liver consumption includes a liver waste body, a rubber stopper fitted to the liver waste body, And an accommodating space formed so as to be connected to the other one of the openings of the liver-consuming body, wherein the handle portion is fitted in a rubber stopper, and the collecting portion is accommodated in the accommodating space. The cell collector according to claim 8, wherein a headgear for closing an inlet of the accommodating space is connected to the simple case. The cell collector according to claim 9, wherein the head gear is formed with a protective space which opens to one side of the head gear and is connected to the accommodating space when the head gear is connected to the liver waste. Wherein the cell collecting part includes the following objects: liver consuming; the liver consuming includes a body, a rubber stopper provided on one side of the body, a second end connected to the rubber stopper formed inside the body, Wherein a space having an inlet is formed on the other side, and a connecting portion connecting the body to one side of the space inlet of the liver-
A cell collector, and an activity plug are installed in the small cell, and the cell collector includes a handle part fitted to the rubber stopper and a cell collecting part inside the space,
And the cell collecting part is fixed to one side of the handle part. The cell collecting part according to claim 11, wherein the cell collecting part includes a basic part, an antibody layer attached to the outside of the basic part and used for capturing a target cell. 13. The cell collection component of claim 12, wherein a metal plating layer is provided on the outside of the base portion, and the antibody layer is on the metal plating layer. 13. The cell collection component of claim 12, wherein a biocompatible polymer layer is disposed on the exterior of the base portion and the antibody layer is on the bio-compatible polymer layer. 13. The cell collection component of claim 12, wherein a metal plating layer and a biocompatible polymer layer are sequentially disposed outside the base portion, the antibody layer being on the bio-compatible polymer layer. 13. The cell collection component of claim 12, wherein the base portion is stainless steel, the metal plating layer is a plated layer, and the biocompatible polymer layer is a hydrogel layer. 17. The cell collecting part according to any one of claims 11 to 16, wherein the cross-section of the cell collecting part is a circular or polygonal needle-like structure. 17. The cell collecting part according to any one of claims 11 to 16, wherein the cell collecting part has a spiral needle-like structure. 12. The cell collection component of claim 11, wherein the handle portion has at least one location mark. 12. The apparatus according to claim 11, wherein there is a recessed pitted hole on one side of the body space inlet, a pillar-shaped object connected to the body in the middle of the hole, the space being connected to the pillar- And the connecting portion is a thread provided on the inner wall of the hole.

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