CN205054227U - Subassembly is gathered to cell - Google Patents
Subassembly is gathered to cell Download PDFInfo
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- CN205054227U CN205054227U CN201520590382.8U CN201520590382U CN205054227U CN 205054227 U CN205054227 U CN 205054227U CN 201520590382 U CN201520590382 U CN 201520590382U CN 205054227 U CN205054227 U CN 205054227U
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- cell collection
- cell
- collection assembly
- assembly according
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Abstract
The utility model provides a subassembly is gathered to cell, it includes the heparin cap and moves about to insert and locate cell collector on the heparin cap, the heparin cap includes the body the one end of body is equipped with the plug, in this is internal still be formed with with the plug meet and in the other end open -ended cavity of body on the body in the opening one end of cavity is equipped with and is used for connecting the connecting portion of body, the cell collector is located including inserting the handheld portion of plug department, and link firmly in the one end of handheld portion, place in and cell collection portion in the cavity. Subassembly is gathered to cell can overcome the not enough of the current cell mode of gathering, the collection of cell in the blood of being convenient for.
Description
Technical field
This utility model relates to medical apparatus technique field, particularly a kind of cell collection assembly.
Background technology
Gather the relevant cell in blood of human body, by the detection of this cell or cultivation, to carry out medical diagnosis on disease or treatment by more and more many uses.Carry out cell collection at present mostly also to be and to carry out blood sampling, then in the blood of sampling, extract required cell.Because blood sampling amount is general all less, thus the cell quantity collected can be caused also less, and leaving human body because of blood, the cell in it also easily loses activity, and these factors all make existing cell collection mode be difficult to meet the requirement of the efficient diagnosis and treatment of disease.
Utility model content
In view of this, this utility model is intended to propose a kind of cell collection assembly, can overcome the deficiency of existing cell collection mode, is convenient to the collection of cell within a cell.
For achieving the above object, the technical solution of the utility model is achieved in that
A kind of cell collection assembly, it comprises:
Calparine cap, described calparine cap comprises body, plug is provided with in one end of described body, also being formed in described body and connecting with described plug and the cavity of other end opening in described body, being provided with the connecting portion for connecting described body in the open at one end of described cavity on the body;
Cellular collector, activity is inserted on described calparine cap, and described cellular collector comprises the Handheld Division being inserted in described plug place, and is fixed on one end of described Handheld Division and the cell collection portion be built in described cavity.
Further, described cell collection portion comprises matrix, and covers the antibody layer for target acquisition cell in described matrix outer circumferential side.
Further, be covered with metal coating at the outer circumferential side of described matrix, described antibody layer is positioned on metal coating.
Further, be covered with biocompatible polymer layer at the outer circumferential side of described matrix, described antibody layer is positioned on biocompatible polymer layer.
Further, be covered with metal coating and biocompatible polymer layer successively at the outer circumferential side of described matrix, described antibody layer is positioned on biocompatible polymer layer.
Further, described matrix is rustless steel, and described metal coating is Gold plated Layer, and described biocompatible polymer layer is hydrogel layer.
Further, described cell collection portion is circular in cross-section or polygonal acicular texture.
Further, described cell collection portion is spiral type acicular texture.
Further, described Handheld Division is provided with at least one gear mark.
Further, the shrinkage pool of indent is formed on the body in the open at one end of cavity, the cylinder be fixed on body is provided with in the middle part of described shrinkage pool, described cavity prolongs and is opened on the end of described cylinder in described cylinder, and described connecting portion is be located at the female thread on described shrinkage pool inwall.
Relative to prior art, this utility model has following advantage:
(1) cell collection assembly described in the utility model, by arranging cellular collector on calparine cap, can when cell collection, calparine cap is connected on remaining needle, and make the cell collection portion on cellular collector insert in human vas, directly to gather cell required in human vas.Because blood continues to flow through cell collection portion in the blood vessel, compared to existing blood sampling form, its cell quantity that can touch greatly increases, and cytoactive also can not lose, and thus can improve the reliability of cell collection.Meanwhile, inserted in cell collection portion after in human vas, only need wait for cell collection portion quietly carries out cell collection, decreases all multioperations of existing blood sampling form, thus also makes cell collection become more convenient, have good practicality.
(2) matrix is as carrier, and metal coating and biocompatible polymer layer are used for the antibody layer fixedly carrying out cell collection.Cell collection portion is cylindrical or spiral acicular texture, the amount of antibody layer can be made different, to adapt to different cell collection needs.
(3) matrix is rustless steel, and metal coating is Gold plated Layer, and biocompatible polymer layer is that hydrogel layer can make antibody layer be arranged at place of collection portion, and keeps the stability of antibody layer character.
(4) length that gear mark can contribute to controlling when cell collection in cell collection portion intravasation is set.
(5) connection that connecting portion can be convenient between calparine cap and associated components is set, shrinkage pool is set and makes connecting portion be set to female thread, calparine cap can be made to connect the overall structure after corresponding component compacter.
Accompanying drawing explanation
The accompanying drawing forming a part of the present utility model is used to provide further understanding of the present utility model, and schematic description and description of the present utility model, for explaining this utility model, is not formed improper restriction of the present utility model.In the accompanying drawings:
Fig. 1 is the structure diagram of the cell collection assembly described in this utility model embodiment;
Fig. 2 is the structure diagram of the cellular collector described in this utility model embodiment;
Fig. 3 is the partial enlarged drawing of part A in Fig. 2;
Fig. 4 is the structure diagram of the calparine cap described in this utility model embodiment;
Fig. 5 is the sectional view in B-B face in Fig. 4;
Description of reference numerals:
1-cellular collector, 2-calparine cap, 11-cell collection portion, 12-Handheld Division, 13-gear identifies, 21-body, 22-plug, 23-main body, 24-cavity, 25-shrinkage pool, the 26-conical surface, 27-female thread, the anti-skidding lines of 28-, 111-matrix, 112-metal coating, 113-biocompatible polymer layer, 114-antibody layer.
Detailed description of the invention
It should be noted that, when not conflicting, the embodiment in this utility model and the feature in embodiment can combine mutually.
Below with reference to the accompanying drawings and describe this utility model in detail in conjunction with the embodiments.
The present embodiment relates to a kind of cell collection assembly, and as shown in fig. 1, it comprises calparine cap 2, and is inserted in the cellular collector 1 on calparine cap 2.Wherein, as shown in Figures 2 and 3, this cellular collector 1 comprises Handheld Division 12 and is fixed on the cell collection portion 11 that one end, Handheld Division 12 is needle-like the structure of cellular collector 1.Cell collection portion 11 comprises matrix 111, and covers successively in the metal coating 112 of matrix 111 outer circumferential side, biocompatible polymer layer 113 and the antibody layer 114 for target acquisition cell.Certainly, except making antibody layer 114 be placed on matrix 111 via metal coating 112 and biocompatible polymer layer 112, antibody layer 114 also can be made only to be placed on matrix 111 via metal coating 112 or biocompatible polymer layer 112.
In the present embodiment, matrix 111 is for adopting rustless steel, and it can be the cylindrical acicular texture that cross section as shown in Figure 2 is circle, and except being cylindrical acicular texture, it is triangle, square, rhombus, regular pentagon, regular hexagon or pentagon arbitrarily that matrix 111 also can be cross section, the polygonized structures such as any hexagon, or matrix 111 also can be spiral acicular texture.In the present embodiment, Handheld Division 12 is the stainless steel structure of cylindricality, and Handheld Division 12 is integral type structure with the matrix 111 in cell collection portion 11, thus is convenient to the manufacture of this cellular collector 1.Certainly except adopting rustless steel, matrix 111 and Handheld Division 12 also can adopt other material, as glass fibre or the plastic stool based on organic polymer.The metal coating 112 covered in the present embodiment in matrix 111 outer circumferential side is Gold plated Layer, and except being Gold plated Layer, metal coating 112 also can adopt nickel, copper, palladium or the metal such as silver, platinum.Biocompatible polymer layer 113 can be employing hydrogel layer, and certainly except being hydrogel, biocompatible polymer layer 113 also can adopt other to have the material of water-wet behavior.
In the present embodiment, outermost antibody layer 114 for being fixed on biocompatible polymer layer 113 has bioactive antigen-antibody, this antigen-antibody can when cell collection portion 11 enters in human vas, the specific cells in blood is caught by immunoreation, namely required target cell, as tumor cell etc.According to the difference of required target cell, antigen-antibody can be variety classes.In the present embodiment as shown in Figure 2, for being convenient to control the inlet of cell collection portion 11 in blood vessel when cell collection, Handheld Division 12 is provided with two gear marks 13, certainly except being set to two, gear mark 13 also can be designed to other quantity, as required as one or three, four etc.And for the ease of cellular collector 1 in update, also can arrange not shown hand termination relative to the other end of cell collection portion 11 in Handheld Division 12 in the present embodiment, this hand termination can be hemispherical dome structure, or also can be platy structure.
The structure of the calparine cap 2 of the present embodiment as shown in Figures 4 and 5, it comprises body 21, plug 22 is provided with in one end of body 21, also comprise and be formed at connecting with plug 22 in body 21, and the cavity 24 of other end opening in body 21, body 21 is also provided with the connecting portion for connecting body 21 in the open at one end of cavity 24.Namely cellular collector 1 is inserted on plug 22, and cell collection portion 11 is built in cavity 24.
In the present embodiment, body 21 can by plastic warp injection mo(u)lding, and plug 22 is for being installed on the end of body 21, and a side end face of plug 22 leaks outside in the end of body 21.In the present embodiment, plug 22 can adopt rubber or silica gel material, and on body 21, the shrinkage pool 25 of indent is also provided with relative to the other end of plug 22, and in shrinkage pool 25, be also provided with the cylinder 23 be fixed on body 21, cavity 24 is namely by body 21 to prolong and in cylinder 23, and open-ended at cylinder 23 of cavity 24.
The connecting portion be arranged in the present embodiment on body 21 is be formed at the female thread 27 on shrinkage pool 25 inwall, and after adopting female thread 27 that calparine cap 2 can be made to be connected with other component, its overall structure is comparatively compact, so that place and use.Certainly except being female thread 27, connecting portion also can be the external screw thread be formed on body 21 outer peripheral face, and now on body 21, still can arrange shrinkage pool 25 and cylinder 23, or also can not arrange shrinkage pool 25 on body 21, and make cavity 24 for running through body 21, open-ended with at body 21.By the free end of cylinder 23 in the present embodiment, also namely the open at one end of cavity 24 is inside, and the outer peripheral face of cylinder 23 is the gradually little taper in cross section, now as shown in Figure 4, the outer peripheral face of cylinder 23 forms the conical surface 26, designs this conical surface 26 and can be convenient to calparine cap 2 and be connected with other component via female thread 27.
And in order to avoid stabbing finger when being plugged at plug 22 place of cellular collector 1 on calparine cap 2, the one end being close to plug 22 in the present embodiment on the outer peripheral face of body 21 also can be formed with the flange of not shown crowned, by the setting of flange, can provide finger and block, thus avoid cellular collector 1 to stab finger because offseting because of carelessness.Flange can be set in the form of a ring, or also can be spaced multiple platy structure.In the present embodiment as shown in Figure 4, for ease of the attended operation of calparine cap 2 with other parts (as remaining needle), the open at one end that the outer peripheral face of body 21 is close to cavity 24 is also formed with anti-skidding lines 28.Anti-skidding lines 28 can be the vertical raised structures shown in Fig. 4, and certainly except vertical raised structures, anti-skidding lines 28 also can adopt other version, as can be the block structure or multiple annular projections etc. of multiple projection.
This cell collection assembly in use, calparine cap 2 can be connected to via the female thread 27 on it be arranged at human vas place remaining needle on, then operating Handheld Division 12 makes cell collection portion 11 enter in human vas, carries out target cell gather by antibody layer in cell collection portion 11 114.And when cell collection assembly does not use; by female thread 27 calparine cap 2 connecting the housing that has opening cavity volume; to close the cavity 24 being equipped with cell collection portion 11, can protect cell collection portion 11 thus, so that the protectiveness of cell collection assembly stores.
The foregoing is only preferred embodiment of the present utility model; not in order to limit this utility model; all within spirit of the present utility model and principle, any amendment done, equivalent replacement, improvement etc., all should be included within protection domain of the present utility model.
Claims (10)
1. a cell collection assembly, is characterized in that comprising:
Calparine cap, described calparine cap comprises body, plug is provided with in one end of described body, also being formed in described body and connecting with described plug and the cavity of other end opening in described body, being provided with the connecting portion for connecting described body in the open at one end of described cavity on the body;
Cellular collector, activity is inserted on described calparine cap, and described cellular collector comprises the Handheld Division being inserted in described plug place, and is fixed on one end of described Handheld Division and the cell collection portion be built in described cavity.
2. cell collection assembly according to claim 1, is characterized in that: described cell collection portion comprises matrix, and covers the antibody layer for target acquisition cell in described matrix outer circumferential side.
3. cell collection assembly according to claim 2, it is characterized in that: be covered with metal coating at the outer circumferential side of described matrix, described antibody layer is positioned on metal coating.
4. cell collection assembly according to claim 2, it is characterized in that: be covered with biocompatible polymer layer at the outer circumferential side of described matrix, described antibody layer is positioned on biocompatible polymer layer.
5. cell collection assembly according to claim 2, is characterized in that: be covered with metal coating and biocompatible polymer layer successively at the outer circumferential side of described matrix, described antibody layer is positioned on biocompatible polymer layer.
6. cell collection assembly according to claim 5, is characterized in that: described matrix is rustless steel, and described metal coating is Gold plated Layer, and described biocompatible polymer layer is hydrogel layer.
7. cell collection assembly according to any one of claim 1 to 6, is characterized in that: described cell collection portion is circular in cross-section or polygonal acicular texture.
8. cell collection assembly according to any one of claim 1 to 6, is characterized in that: described cell collection portion is spiral type acicular texture.
9. cell collection assembly according to claim 1, is characterized in that: on described Handheld Division, be provided with at least one gear mark.
10. cell collection assembly according to claim 1, it is characterized in that: the shrinkage pool being formed with indent on the body in the open at one end of cavity, the cylinder be fixed on body is provided with in the middle part of described shrinkage pool, described cavity prolongs and is opened on the end of described cylinder in described cylinder, and described connecting portion is be located at the female thread on described shrinkage pool inwall.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520590382.8U CN205054227U (en) | 2015-08-07 | 2015-08-07 | Subassembly is gathered to cell |
| KR2020160004021U KR200486491Y1 (en) | 2015-08-07 | 2016-07-12 | A cell-collection device and a cell-collection assembly |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201520590382.8U CN205054227U (en) | 2015-08-07 | 2015-08-07 | Subassembly is gathered to cell |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN205054227U true CN205054227U (en) | 2016-03-02 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201520590382.8U Active CN205054227U (en) | 2015-08-07 | 2015-08-07 | Subassembly is gathered to cell |
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| Country | Link |
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| CN (1) | CN205054227U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107625524A (en) * | 2016-07-18 | 2018-01-26 | 上海千山医疗科技有限公司 | PICC/CVC components and circulating tumor cell are in body acquisition equipment |
| CN107625534A (en) * | 2016-07-18 | 2018-01-26 | 上海千山医疗科技有限公司 | Indwelling needle assembly and the circulating tumor cell supporting with remaining needle are in body acquisition equipment |
-
2015
- 2015-08-07 CN CN201520590382.8U patent/CN205054227U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107625524A (en) * | 2016-07-18 | 2018-01-26 | 上海千山医疗科技有限公司 | PICC/CVC components and circulating tumor cell are in body acquisition equipment |
| CN107625534A (en) * | 2016-07-18 | 2018-01-26 | 上海千山医疗科技有限公司 | Indwelling needle assembly and the circulating tumor cell supporting with remaining needle are in body acquisition equipment |
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| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190513 Address after: 050035 7th Floor, Building No. 136 Yellow River Avenue, Shijiazhuang High-tech Zone, Hebei Province Patentee after: Germany Road (Shijiazhuang) Biotechnology Co., Ltd. Address before: Room 409, Block A, China Foreign Language Building, 89 West Third Ring North Road, Haidian District, Beijing, 100089 Patentee before: BEIJING DELUTONG BIOTECHNOLOGY CO., LTD. |
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| TR01 | Transfer of patent right |