KR20160126075A - 펩티드 및 사용 방법 - Google Patents

펩티드 및 사용 방법 Download PDF

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KR20160126075A
KR20160126075A KR1020167026913A KR20167026913A KR20160126075A KR 20160126075 A KR20160126075 A KR 20160126075A KR 1020167026913 A KR1020167026913 A KR 1020167026913A KR 20167026913 A KR20167026913 A KR 20167026913A KR 20160126075 A KR20160126075 A KR 20160126075A
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마이클 도칼
토마스 폴라코프스키
프랭크 오스테르캠프
루돌프 하트만
마티아스 파슈케
베티나 하트리에브
프리드리히 쉬헤이플린저
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쓰리비 파마슈티컬스 게엠베하
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    • C07—ORGANIC CHEMISTRY
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

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Abstract

본 발명은 단백질 S에 결합하고, 선택적으로 단백질 S를 억제하는 펩티드를 포함하는 펩티드, 및 이의 조성물을 제공한다. 상기 펩티드는, 예를 들어, 단백질 S의 활성을 억제하고, 개체에서 트롬빈 형성을 향상시키고, 개체에서 혈전 형성을 증가시키며, 개체에서 혈액 응고 질환을 치료하고, 단백질 S를 정제하며, 단백질 S 결합 화합물을 식별하는 데 이용할 수 있다.

Description

펩티드 및 사용 방법{PEPTIDES AND METHODS OF USE}
발명의 기술분야
본 발명은 일반적으로 단백질 S에 결합하는 펩티드 및 그의 용도에 관한 것이다.
관련 출원의 상호-참조
본 출원은 2014년 2월 28일에 출원된 미국 가특허 출원 제 61/946,103호에 대해 우선권을 주장하고, 이는 전체가 참고로서 본 명세서에 인용된다.
참조로서의 포함
본 명세서와 함께 제출된 컴퓨터-판독가능한 뉴클레오타이드/아미노산 서열 목록이 그 전체가 참조로서 포함되며 하기와 같이 표시된다: 2015년, 2월 31일에 생성된, 1,390,466 바이트의 "46380A_SeqListing.txt" 명칭의 ASCII 텍스트 파일.
지혈(Hemostasis)은 복합 응집 캐스케이드에 의존하며, 여기서 혈액 응고 인자에 의해 매개되는 일련의 과정들은 프로트롬빈이 트롬빈으로 전환되게 한다. 인자 X(Fact 또는 X, FX) 활성화는 응집 캐스케이드의 내인성 및 외인성 경로 둘 다의 중심적인 과정이다. 외인성 경로는 응집 캐스케이드의 일차 활성화제로서 제안되었다(Mackman et al., Arterioscler . Thromb . Casc . Biol ., 27, 1687-1693 (2007)). 순환하는 조직 인자(Tissue Factor, TF) 및 활성화된 인자 VII(FVIIa)가 상호작용하여 "외인성 복합체"를 형성하고, 이는 FX의 활성화를 매개한다. 응집 캐스케이드는 내인성 경로에 의해 증폭되며, 그 과정에서 인자 XII, XI, IX, 및 VIII의 연속적인 활성화가 역시 FX 활성화를 매개하는 "내인성" FIXa-FVIIIa 복합체의 형성을 유도한다. 활성화된 FX는 피브린을 생성하고 효과적으로 출혈을 억제하기 위해 신체가 필요로 하는 트롬빈 형성을 촉진한다. 응집은 단백질 C-매개 항응집 경로에 의해 하향-조절된다. 트롬보모듈린과 함께 복합체에서 트롬빈은 단백질 C를 활성화시킨다. 활성화된 단백질 C와 이의 보조 인자인 단백질 S는 활성화된 혈액 인자 V (FVa) 및 VIII(FVIIIa)를 분해 및 비활성화시킨다.
혈우병(hemophilia)과 같은 중증 출혈 장애는 혈액 응고 장애 캐스케이드의 붕괴로부터 기인한다. 인자 대체 요법이 혈액 응고 장애를 위한 가장 일반적인 치료법이다. 그러나, 전형적으로 혈액 응고 인자는 투여 후 바로 혈류로부터 제거된다. 효과적이기 위해, 환자는 혈장-유래 또는 재조합 인자 농축액의 정맥 주사를 빈번하게 맞아야 하는데, 이는 불편하며, 전문 의료 설비를 필요로 하고, 고비용인데다 시간소모적이다. 항-인자 항체를 갖는 환자에 대해서는 소수의 치료적 선택사항만이 존재한다.
발명의 요약
본 발명은, 예를 들면, 아미노산 서열 VSAGWYDYNTDTYYEF (서열번호 2920)와 최소 50 % 동일한 아미노산 서열을 포함하고 화학식 I의 구조를 갖는 펩티드를 포함하며: X1004-X1005-X1006-X1007-X1008-X1009-X1010-X1011-X1012-X1013-X1014-X1015-X1016-X1017-X1018-X1019, 상기 X1004는 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, Tle, V, v, W, 또는 Y; 상기 X1005는 A, C, D, Dap, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, s, T, V, W, 또는 Y; 상기 X1006은 A, a, Aib, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, s, T, Tle, V, W, 또는 Y; 상기 X1007은 A, a, Aib, C, D, E, F, G, H, I, K, L, M, N, Nmg, P, p, Q, R, S, s, T, Tle, V, W, 또는 Y; 상기 X1008은 1Ni, 2Ni, A, Bta, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, w, 또는 Y; 상기 X1009는 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, Y, 또는 w; 상기 X1010은 A, C, D, d, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, w, 또는 Y; 상기 X1011은 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, Y, 또는 w; 상기 X1012는 A, C, D, E, F, G, H, I, K, L, M, N, n, P, p, Q, R, S, T, V, W, 또는 Y; 상기 X1013은 A, a, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, t, V, W, 또는 Y; 상기 X1014는 A, C, D, d, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y; 상기 X1015는 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, t, Tle, V, W, 또는 Y; 상기 X1016은 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y; 상기 X1017은 A, C, D, E, F, G, H, I, K, L, M, N, Nle, P, p, Q, R, S, T, V, W, Y, 또는 y; 상기 X1018은 A, C, D, E, e, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y; 및 상기 X1019는 A, C, D, E, F, f, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y (서열번호 2921)이다. 다양한 구현예에서, 상기 펩티드는 X1004에 직접적으로 연결된 1 종 이상의 N-말단 아미노산(들)을 추가적으로 포함하며, 상기 N-말단 아미노산(들)은 X1003, X1002-X1003, 및 X1001-X1002-X1003로 이루어진 군으로부터 선택되는 아미노산 서열을 포함한다. 이런 점에서, 상기 X1003은 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, Tle, V, W, Y, 또는 y; 상기 X1002는 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, Y, 또는 y; 및 상기 X1001은 A, Bpa, C, D, E, e, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y (서열번호 2922)이다. 대안적으로 또는 부가적으로, 상기 펩티드는 X1019에 직접적으로 연결된 C-말단 아미노산을 추가적으로 포함하며, A, C, D, E, e, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 및 Y (서열번호 2923)로 이루어진 군으로부터 선택된다. 예를 들어, 다양한 구현예에서, 상기 펩티드는 EYYVSAGWYDYNTDTYYEFE (서열번호 2924)와 최소 약 80% 동일한 아미노산을 포함한다. 본 발명은 서열번호 1-2916, 2920, 및 2924로 이루어진 군으로부터 선택된 아미노산 서열을 포함하는(또는 이루어진) 펩티드를 포함한다.
또한, 본 발명은 본 발명의 펩티드(들)를 사용하는 방법을 제공한다. 예를 들어, 본 발명은 개체에서의 단백질 S의 활성을 억제하는 방법을 제공한다. 또한,질환으로 고통받거나 질환으로 고통받을 위험이 있는 개체를 치료하기 위한 방법을 제공한다. 또한, 본 발명은 개체에서 트롬빈 형성을 증진하는 방법, 개체에서 혈전(blood clot) 형성을 개선하기 위한 방법, 개체에서 혈액 응고 질환과 같은 질환 또는 장애를 치료하는 방법을 제공한다. 또한, 상기 방법들은, 본 명세서에서 그 전체로서, 예컨데, "본 발명의 방법"으로 지칭된다. 상기 방법은 개체에게 원하는 효과를 달성하기 위한 유효량, 예컨대, 개체에서 단백질 S의 활성 억제, 트롬빈 형성 증가, 혈전 형성 증가, 또는 혈액 응고 질환을 치료하기에 효과적인 양의 본 명세서에 기재된 펩티드를 투여하는 단계를 포함한다. 본 발명의 추가적인 양태는 약제 또는 약제의 제조를 위한 본 발명의 펩티드의 사용을 포함한다.
도 1A-C는 추적자 펩티드로 JBS0684를 이용한 LANCE IC50 분석에 의해 측정된 본 명세서에 기재된 다양한 펩티드의 결합 친화성(평균 IC50[nM])을 제공하는 차트이다.
도 2A-JJ는 본 명세서에 기재된 다양한 펩티드의 아미노산 서열을 제공하는 차트이다.
본 발명은 단백질 S에 결합하고, 일부 경우, 혈액 응고 캐스케이드 내의 단백질 S의 억제(즉, 응고) 활성을 차단하는 펩티드를 제공한다. 단백질 S는APC(activated Protein C)에 대한 공동인자로서 기능하여 FVa(Factors Va) 및 VIIIa(FVIIIa)를 저하시킨다. 단백질 S의 억제는 단백질 C-매개 FVa 및 FVIIIa 분해를 감소시키고, 이는 혈액 인자가 혈액 응고 캐스케이드에서 기능하여 트롬빈을 생성하고 궁극적으로 피브린을 생성하도록 한다. 단백질 S는 Gla(γ-carboxy-glutamic acid) 도메인, 트롬빈-민감성 모듈(thrombin-sensitive module), EGF(epidermal growth factor)-유사 도메인 및 성 호르몬 결합 글로불린(sex hormone binding globulin)에 유사성을 갖는 영역(region)을 포함하는, 70 kD의 비타민 K 의존성 당 단백질이며, 635 아미노산의 길이이다. 상기 단백질은 혈장에서 유리(free)한 것으로 발견되며, 또한, 보체 단백질 C4BP(C4b-binding protein)와 복합체를 이룬다. 유리(free) 단백질 S는 APC 공동인자로 작용하며; 복합체 형태는 공동인자 활성을 가지고 있지 않는다. 단백질 S는 인지질-함유 막에 대한 APC의 친화성을 증가시키고, FVa의 R306에서 APC-매개 절단을 향상시키며, FVIIIa의 APC-매개 비활성화를 향상시킨다. Walker, J. Biol . Chem., 256(21), 11128-11131 (1981); Rosing et al., J. Biol . Chem ., 270(46), 27852-27858 (1995). 또한, 단백질 S는 APC의 독립적 응고를, 예를 들어, FXa 및 FVa에 결합하여 방해한다. Hackeng, J. Biol . Chem ., 269(33), 21051-21058 (1994). 인간 단백질 S의 서열은 서열번호 2917(서열번호 2918로 제공된 핵산 서열)로서 제공된다. 본 발명은 일 양태에서, 하나 이상의 단백질 S의 활성을 선택적으로 차단하는 펩티드 S-결합 펩티드를 제공하며, 이에 의해 선택적으로 트롬빈 형성이 향상된다. 본 개시의 내용 중에서, 본 명세서에 기술된 화학식 I 및 본 명세서에 기술된 임의의 단백질 S-결합 펩티드에 포함되는 임의의 펩티드는 또한 "본 발명의 펩티드" 및 "본 명세서에 기술된 펩티드"로 지칭된다. "펩티드(Peptide)"는 통상적인 펩티드(즉, 통상적인 펩티드 백본을 갖는)뿐만 아니라 펩티드유사체(peptidomimetic)(즉, 변형된 백본 및 선택적으로 아미노산에서 발견되는 측-쇄를 갖는 단백질-유사 폴리머)를 포함하는 것을 의미한다.
여러 가지의 펩티드의 아미노산 서열이 본 명세서에 제공된다. 통상적인 아미노산들은 이들의 표준적인, 한-문자 또는 세-문자 코드에 따라 식별된다. 비-통상적인 아미노산 및 추가적인 펩티드 빌딩 블록(building blocks)의 예가 표 1 및 본 명세서 내에, 예를 들면, 3-4 문자/숫자 코드(일반적인 네 문자 축약어인, Ttds 및 Dopa는 제외)로 기재되어있다. 비-통상적인 아미노산 및 빌딩 블록의 화학적 구조는 당업계에 공지되어 있고 예를 들어,미국 특허 출원 공개 번호 2013/0252896에 기재되고, 본 명세서에서 표 1 내지 표 3을 포함하여 그 전체가 참조로 인용된다.
본 명세서에 제공된 펩티드의 아미노산 서열은 전형적인 펩티드 서열 형식으로 도시된다. 예를 들면, 아미노산의 세-문자 코드 또는 한-문자 코드가 펩티드 서열 내 특정한 위치에서 아미노산의 존재를 나타낸다. 각각의 비-통상적 아미노산 또는 빌딩 블록에 대한 코드는 많은 경우 서열에서 다음 및/또는 이전 아미노산 또는 빌딩 블록에 대한 코드에 하이픈(hyphen)으로 연결된다. 인접한 아미노산은 화학적 결합(전형적으로 아미드 결합)에 의해 연결된다. 화학적 결합의 형성은 인접한 아미노산의 왼편에 위치한 경우(예컨대, Hle-인접한 아미노산), 아미노산의 1-카르복실 기로부터 히드록실 기를 제거하고 인접한 아미노산의 오른편에 위치한 경우(예컨대, 인접한 아미노산-Hle) 아미노산의 아미노 기로부터 수소를 제거한다. 상기 두 개질이 모두 동일한 아미노산에 적용될 수 있고 분명하게 표시된 하이픈 없이 아미노산 서열에 존재하는 인접한 통상적 아미노산에 적용될 수 있음이 이해된다. 아미노산이 아미노산 측쇄에 하나 초과의 아미노 및/또는 카르복시 기를 포함하는 경우, 펩티드 결합의 형성을 위해 일반적으로 2- 또는 3-아미노 기 및/또는 1-카르복시 기가 사용된다. 일부 비-통상적 아미노산에 있어서, 첫 번째 문자가 C-α-원자의 입체화학을 의미하는 경우 3-문자 코드가 사용되었다. 예를 들면, 대문자인 첫 번째 문자는 아미노산의 L-형태가 펩티드 서열에 존재하는 것을 의미하는 반면, 소문자인 첫 번째 문자는 상응하는 아미노산의 D-형태가 펩티드 서열에 존재함을 의미한다. 한-문자 코드가 사용된 경우, 소문자 문자는 D-아미노산을 나타내는 반면, 대문자인 문자는 L-아미노산을 나타낸다. 반대로 지시되지 않는 한, 본 명세서에서 아미노산 서열은 N-에서 C-말단 방향으로 제시된다.
본 명세서에 기술된 여러 펩티드 서열의 C-말단은 OH, NH2의 포함, 또는 하이픈을 통해 C-말단 아미노산 코드에 연결된 특정 말단 아민에 대한 축약으로 분명하게 예시된다. 본 명세서에 기술된 여러 펩티드의 N-말단은 수소의 포함(유리 N-말단에 대해), 또는 하이픈을 통해 N-말단 아미노산 코드에 연결된 특정 말단 카르복실산 또는 기타 화학적 기에 대한 축약으로 분명하게 예시된다.
본 발명은 화학식 I의 구조를 포함하는 펩티드를 제공한다: X1004-X1005-X1006-X1007-X1008-X1009-X1010-X1011-X1012-X1013-X1014-X1015-X1016-X1017-X1018-X1019, 상기 X1004는 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, Tle, V, v, W, 또는 Y; 상기 X1005는 A, C, D, Dap, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, s, T, V, W, 또는 Y; 상기 X1006은 A, a, Aib, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, s, T, Tle, V, W, 또는 Y; 상기 X1007은 A, a, Aib, C, D, E, F, G, H, I, K, L, M, N, Nmg, P, p, Q, R, S, s, T, Tle, V, W, 또는 Y; 상기 X1008은 1Ni, 2Ni, A, Bta, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, w, 또는 Y; 상기 X1009는 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, Y, 또는 w; 상기 X1010은 A, C, D, d, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, w, 또는 Y; 상기 X1011은 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, Y, 또는 w; 상기 X1012는 A, C, D, E, F, G, H, I, K, L, M, N, n, P, p, Q, R, S, T, V, W, 또는 Y; 상기 X1013은 A, a, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, t, V, W, 또는 Y; 상기 X1014는 A, C, D, d, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y; 상기 X1015는 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, t, Tle, V, W, 또는 Y; 상기 X1016은 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y; 상기 X1017은 A, C, D, E, F, G, H, I, K, L, M, N, Nle, P, p, Q, R, S, T, V, W, Y, 또는 y; 상기 X1018은 A, C, D, E, e, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y; 및 상기 X1019는 A, C, D, E, F, f, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y (서열번호 2921)이다.
다양한 실시예에서, 본 발명은 아미노산 서열 VSAGWYDYNTDTYYEF (서열번호 2920)와 최소 약 50% 동일한(예컨대, 최소 55% 동일, 최소 60% 동일, 최소 65% 동일, 최소 70% 동일, 최소 75% 동일, 최소 80% 동일, 최소 85% 동일, 또는 최소 90% 동일) 아미노산 서열을 포함하고 화학식 I의 구조를 갖는 펩티드를 제공하며, 상기 X1004는 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, Tle, V, v, W, 또는 Y; 상기 X1005는 A, C, D, Dap, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, s, T, V, W, 또는 Y; 상기 X1006은 A, a, Aib, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, s, T, Tle, V, W, 또는 Y; 상기 X1007은 A, a, Aib, C, D, E, F, G, H, I, K, L, M, N, Nmg, P, p, Q, R, S, s, T, Tle, V, W, 또는 Y; 상기 X1008은 1Ni, 2Ni, A, Bta, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, w, 또는 Y; 상기 X1009는 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, Y, 또는 w; 상기 X1010은 A, C, D, d, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, w, 또는 Y; 상기 X1011은 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, Y, 또는 w; 상기 X1012는 A, C, D, E, F, G, H, I, K, L, M, N, n, P, p, Q, R, S, T, V, W, 또는 Y; 상기 X1013은 A, a, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, t, V, W, 또는 Y; 상기 X1014는 A, C, D, d, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y; 상기 X1015는 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, t, Tle, V, W, 또는 Y; 상기 X1016은 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y; 상기 X1017은 A, C, D, E, F, G, H, I, K, L, M, N, Nle, P, p, Q, R, S, T, V, W, Y, 또는 y; 상기 X1018은 A, C, D, E, e, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y; 및 상기 X1019는 A, C, D, E, F, f, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y (서열번호 2921)이다.
본 발명의 다양한 구현예에서, 상기 X1004는 A, E, F, G, H, I, K, L, M, N, P, Q, R, T, V, W, 또는 Y; X1005는 A, D, E, F, G, H, I, K, L, M, N, R, S, T, V, W, 또는 Y; X1006은 A, a, F, G, H, I, L, M, P, S, T, V, W, 또는 Y; X1007은 G 또는 a; X1008은 F, H, L, W, 또는 Y; X1009는 F 또는 Y; X1010은 A, D, E, F, G, H, I, K, L, M, N, Q, R, S, T, V, W, 또는 Y; X1011은 A, E, F, G, H, I, K, L, M, N, P, Q, R, S, T, V, W, 또는 Y; X1012는 A, D, E, F, G, H, I, K, L, M, N, n, P, Q, R, S, T, V, W, 또는 Y; X1013은 A, D, E, F, G, H, I, K, L, M, N, Q, R, S, T, V, W, 또는 Y; X1014는 A, D, d, E, G, H, N, Q, 또는 S; X1015는 A, D, E, F, G, H, I, K, L, M, N, Q, R, S, T, V, W, 또는 Y; X1016은 A, D, E, F, H, I, L, M, N, S, T, W, 또는 Y; X1017은 A, D, E, F, G, H, I, K, L, M, N, Q, R, S, T, V, W, 또는 Y; X1018은 A, D, E, F, G, H, I, K, L, M, N, P, Q, R, S, T, V, W, 또는 Y; 및 X1019는 E, F, f, H, I, L, M, V, W, 또는 Y이다.
일 양태에서, 본 발명의 펩티드는 화학식 I의 구조를 포함하며, 상기 X1004는 A, F, H, I, K, L, T, V, W, 또는 Y (예컨대, X1004는 A, F, I, L, T, V, 및 W로 이루어진 군으로부터 선택된다); X1005는 A, E, F, G, H, I, K, L, M, N, Q, R, S, T, V, W, 또는 Y (예컨대, X1005는 A, E, F, G, H, I, K, L, M, R, S, T, V, W, 및 Y로 이루어진 군으로부터 선택된다); X1006은 A, F, G, I, L, M, V, W, 또는 Y (예컨대, X1006은 A, F, G, I, L, V, W, 및 Y로 이루어진 군으로부터 선택된다); X1007은 G; X1008은 F, L, W, 또는 Y (예컨대, F 또는 Y); X1010은 A, D, E, F, H, I, K, L, M, N, Q, R, S, T, V, W, 또는 Y (예컨대, X1010은 D, E, F, H, I, K, L, N, Q, V, W, 및 Y로 이루어진 군으로부터 선택된다); X1011은 A, F, G, H, I, K, L, M, N, R, S, T, V, W, 또는 Y (예컨대, X1011은 F, G, I, K, L, M, R, T, V, W, 및 Y로 이루어진 군으로부터 선택된다); X1012는 A, D, E, F, G, H, I, K, L, M, N, n, P, Q, R, S, T, V, W, 또는 Y (예컨대, X1012는 D, E, F, G, H, I, K, L, N, Q, R, S, T, V, 및 Y로 이루어진 군으로부터 선택된다); X1013은 D, E, F, G, H, I, K, L, Q, R, S, T, V, 또는 W; X1014는 D, d, E, G, H, 또는 N (예컨대, X1014는 D, E, 및 H로 이루어진 군으로부터 선택된다); X1015는 D, E, H, I, K, M, Q, R, S, T, V, 또는 W; X1016은 D, E, F, H, S, W, 또는 Y (예컨대, X1016은 F, H, W, 및 Y로 이루어진 군으로부터 선택된다); X1017은 D, E, G, H, I, T, W, 또는 Y; X1018은 A, D, E, G, H, I, K, L, M, P, Q, R, S, T, V, 또는 W; 및 X1019는 F, I, M, W, 또는 Y (예컨대, X1019는 F, I, M, 및 W로 이루어진 군으로부터 선택된다)이다. 하나 이상의 양태에서, X1004는 V, X1005는 S, X1006은 A, X1007은 G, X1008은 W, 및 X1009는 Y이다. 선택적으로 상기 펩티드는 VSAGWYDYNTDTYYEF (서열번호 2920)와 최소 50% 동일한 아미노산 서열을 포함한다.
일부 구현예에서, 본 발명의 펩티드는 아미노산 서열의 N- 또는 C-말단에 부착되는 1 종 이상의 추가적인 아미노산 잔기를 포함한다. 예를 들어, 일부 구현예에서, 화학식 I의 구조를 포함하는 펩티드는 X1004에 직접적으로 연결된 1 종 이상의 N-말단 아미노산(들)을 추가적으로 포함하며, 상기 N-말단 아미노산(들)은 X1003, X1002-X1003, 및 X1001-X1002-X1003로 이루어진 군으로부터 선택되는 아미노산 서열을 포함한다. X1003 및 X1002는 독립적으로 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, Tle, V, W, Y, 또는 y로부터 선택된다(예를 들어, X1003 및 X1002는 독립적으로 A, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, y, 또는 Y로부터 선택된다). 예를 들어, 일부 양태에서, X1003은 A, E, F, G, H, I, K, L, N, P, R, T, V, W, y, 또는 Y; 및 X1002는 A, D, E, F, G, H, I, K, L, N, P, R, T, V, W, y, 또는 Y이다. X1001은 A, Bpa, C, D, E, e, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y이다(예를 들어, X1001은 A, D, E, e, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 및 Y로 이루어진 군으로부터 선택된다).
상기 화학식 I에 기재된 코어 구조 외에, 특이적으로 고려되는 다른 구조들은 1 종 이상의 추가적인 아미노산이 X1019에 직접적으로 연결된 코어 구조의 C-말단에 부착된 것이다. 예를 들어, C-말단 추가는 선택적으로 A, D, E, e, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 및 Y로 이루어진 군과 같은 A, C, D, E, e, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 및 Y로 이루어진 군으로부터 선택된 아미노산 서열을 포함한다. 본 발명은 아미노산 서열 EYYVSAGWYDYNTDTYYEFE (서열번호 2924)와 최소 50% 동일성을 포함하고, 화학식 X1001-X1002-X1003-X1004-X1005-X1006-X1007-X1008-X1009-X1010-X1011-X1012-X1013-X1014-X1015-X1016-X1017-X1018-X1019-X1020을 포함하는 펩티드를 추가적으로 제공하며, 각 아미노산 위치는 상기 정의된 바와 같다(서열번호 2923).
본 발명은 (i) 아미노산 서열 VSAGWYDYNTDTYYEF (서열번호 2920), (ii) 아미노산 서열 EYYVSAGWYDYNTDTYYEFE (서열번호 2924), 또는 (iii) 서열번호 1 내지 2916 중 어느 하나의 아미노산 서열과 최소 60% 동일성, 최소 65% 동일성, 최소 70% 동일성, 최소 75% 동일성, 최소 80% 동일성, 최소 85% 동일성, 최소 90% 동일성, 최소 95% 동일성 또는 100% 동일성을 갖는 아미노산 서열을 포함하는 펩티드 또는 이들로 이루어진 펩티드를 포함한다. 본 명세서에 사용된, "최소 60% 동일성(identity)" 및 유사한 용어는 예컨대, 60%, 65%, 70%, 71%, 72%, 73%, 74%, 75%, 76%, 77%, 78%, 79%, 80%, 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98% 또는 99% 등 중 어느 한 정수를 포함한다. 또한, 용어 "최소 [백분율] 동일성"은 동일한 아미노산(또는 펩티드 빌딩 블록)의 수를 본 발명의 펩티드의 아미노산(또는 펩티드 빌딩 블록)의 총 수로 나눈 것보다 크거나 동일한 임의의 백분율을 포함한다([최소 백분율 동일성] ≥ [동일한 아미노산 또는 펩티드 빌딩 블록의 수] / [본 발명의 펩티드의 아미노산 또는 펩티드 빌딩 블록의 총 수]). 2 종 이상의 정렬된 아미노산(또는 뉴클레오티드)의 백분율 동일성(%)의 계산은 당업계에서 잘 이해되며 공지된 컴퓨터 프로그램을 사용하여 통상적으로 결정된다. 예를 들어, 백분율 서열 동일성을 결정하기 위한 2 종 이상의 서열의 정렬 은 NCBI(National Center for Biotechnology Information) 웹사이트에서 이용가능한 BLAST (basic local alignment search tool) 프로그램이 도입된 Altschul 등(Nucleic Acids Res., 25:3389-402 (1997))에 의해 기술된 알고리즘을 이용하여 선택적으로 실시된다. 펩티드는 바람직하게는 단백질 S에 결합하고, 선택적으로 단백질 S 활성을 억제한다.
본 발명은 시클릭 구조를 포함하는 펩티드를 포함한다. 이에 관하여, 본 발명은 펩티드 내에 시클릭 구조(예컨대, 아미노산 간의 결합에 의해 형성된 하나 이상의 루프(loop))를 포함하는 펩티드, 펩티드 서열 내에서 말단 아미노산과 아미노산의 상호작용에 의해 형성된 시클릭 구조를 포함하는 펩티드, 및 머리에서 꼬리로 고리화된(cyclized) 펩티드를 포함한다. 본 발명의 펩티드는, 일부 경우, 분자내 이황화 결합을 포함한다. 일부 구현예에서, 분자내 이황화 결합은 시스테인 잔기에 의해 형성된다. 비-시스테인 잔기, 또는 비-시스테인 잔기 및 시스테인 잔기에 의해 형성된 시클릭 구조를 포함하는 펩티드가 또한 제공된다. 적절한 비-통상적 아미노산 또는 화학적 모이어티는 FA19205(3-[2-(2-{2-[2-(2-Amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-propionic acid), FA19204(3-(2-{2-[2-(2-Amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-propionic acid), FA19203(3-{2-[2-(2-Amino-ethoxy)-ethoxy]-ethoxy}-propionic acid), FA03202([2-(2-Amino-ethoxy)-ethoxy]-acetic acid), Hcy((S)-Homo-cysteine), hcy(D-Homo-cysteine), Cea(Aminoethylthiol), 및 c를 포함하지만 이에 제한되지 않는다.
일부 구현예에서, 본 명세서에 기재된 펩티드는 N- 및/또는 C-말단 또는 펩티드의 내부 잔기에 1 종 이상의 모이어티가 컨쥬게이션 또는 부착된다. 예를 들면, 모이어티는 FAM-Ttds(carboxyfluorescein-Ttds), 프롤린-글루타메이트 태그(tag)("PE"), Palm(Palmitoyl), 2-페닐 아세틸, 3-페닐 프로피오닐, 2-(나프트-2-일) 아세틸, 헥사노일, 2-메틸 프로피오닐, 3-메틸 부타노일, 2-나프틸설포닐, 아세틸, AOA(Aminooxyacetic acid), 레불린산(Lev) 및 펜티노산(Pyn) 및 1-나프틸설포닐, C(NEM)(C, c, N-ethylmaleiimido Ethylmaleiimido cysteine), FA19205(3-[2-(2-{2-[2-(2-Amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-propionic acid), FA19204(3-(2-{2-[2-(2-Amino-ethoxy)-ethoxy]-ethoxy}-ethoxy)-propionic acid), FA19203(3-{2-[2-(2-Amino-ethoxy)-ethoxy]-ethoxy}-propionic acid), FA03202([2-(2-Amino-ethoxy)-ethoxy]-acetic acid), K(Tdts-maleimid), K(AOA)(2-Amino-6-ε-(2-aminooxyAminooxy-acetylamino)-hexanoic acidL-lysine), Cea (Aminoethylthiol), Eag, (S)-Hly(Homo-lysine), K, (S)-Orn(Ornithine), (S)-2,4-Dab(Diaminobutyric acid), (S)-Dap(Diaminopropionic acid), (S)-Hcy(Diaminopropionic acid), Pen(penicillamine), K(Myr)(e-(Myristyl)-L-lysine), K(Ttds-Myr)(e-(Myristyl-Ttds)-L-lysine), K(Ttds-Palm)(e-(Palmityl-Ttds)-L-lysine), K(Ttds-γGlu-Myr)(e-(Myristyl-g-glutamyl-Ttds)-L-lysine), K(AlbuTag)(e-(4-(p-Iodophenyl)butyryl))-L-lysine), K(4PBSA)(e-(4-(Pentyl)-benzolsulfonamidyl)-L-lysine), (S)-4-Bpa(Benzoylphenylalanine), Bpa-K(Bio)-C, C(Atf-Bio), C(Atf-LC-Bio), C(FeBABE), C(MalCy5), C(PEG), e-(Acetyl)-L-lysine (K(Ac)), K(Ttds), K(Ttds-γGlu), K(Glutar), K(Ttds-Mal), T, Ttds, 또는 Ttds-K(Bio)를 포함하나 이에 제한되지 않는다. K(Bio)는 ε-(비오티닐)-L-라이신이다. C(Atf-Bio)는 2-아미노-3-[2-(2-(4-아지도-2,3,5,6-테트라플루오로-벤조일아미노)-6-{6-[5-(2-옥소-헥사히드로-티에노[3,4-d]이미다졸-6-일)-펜타노일아미노]-헥사노일아미노}-헥사노일아미노)-에틸디설파닐]-프로피오닉 산이다. C(Atf-LC-Bio)는 2-아미노-3-[2-(2-[6-(4-아지도-2,3,5,6-테트라플루오로-벤조일아미노)-헥사노일아미노]-6-{6-[5-(2-옥소-헥사히드로-티에노[3,4-d]이미다졸-6-일)-펜타노일아미노]-헥사노일아미노}-헥사노일아미노)-에틸디설파닐]-프로피오닉 산이다. C(FeBABE)는 2-아미노-3-({4-[2,3-비스-(비스-카르복실메틸-아미노)-프로필]-페닐카르바모일}-메틸설파닐)-프로피오닉 산의 Fe(III)-복합체이다. 이것은 티오에테르 결합(linkage) 및 방향족 스페이서를 통한 시스테인 측쇄 중의 황에 연결된 Fe(III)의 EDTA(ethylenediamine tetra acetic acid)-복합체이다. C(MalCy5)는 2-{5-[1-(5-{2-[3-(2-아미노-2-카르복시-에틸설파닐)-2,5-디옥소-피롤리딘-1-일]-에틸카르바모일}-펜틸)-3,3-디메틸-1,3-디히드로-인돌-2-일이딘]-펜타-1,3-디에닐}-1,3,3-트리메틸-3H-인돌리움이다. 이것은 티오에테르 결합을 기반으로 한 말레이미드(maleimide)를 통해 시스테인의 황에 컨쥬게이션된 염료 Cy5이다.
일 양태에서, 펩티드의 아미노산 서열은 보존적 치환을 포함하며, 아미노산 잔기가 유사한 측쇄를 갖는 아미노산 잔기로 대체되는 보존적 치환이다. 유사한 측쇄를 갖는 아미노산 잔기의 패밀리는 당해 분야에 규명되어 있고, 염기성 측쇄(예컨대, 리신, 아르기닌, 및 히스티딘), 산성 측쇄(예컨대, 아스파르트산 및 글루탐산), 하전되지 않은 극성 측쇄(예컨대, 글리신, 아스파라긴, 글루타민, 세린, 트레오닌, 티로신, 및 시스테인), 비극성 측쇄(예컨대, 알라닌, 발린, 류신, 이소류신, 프롤린, 페닐알라닌, 메티오닌, 및 트립토판), 베타-분지된 측쇄(예컨대, 트레오닌, 발린, 및 이소류신) 및 방향족 측쇄(예컨대, 티로신, 페닐알라닌, 트립토판, 및 히스티딘)를 갖는 아미노산을 포함한다. 그러나, 생성되는 펩티드가 전부 또는 부분적으로, 단백질 S에 결합하는 능력 및 선택적으로 하향 조절하는 능력을 보유하는 한, 당업자가 만드는 것이 보존적 치환에 제한되지 않는 점이 이해될 것이다. 예를 들어, 도 1은 JBS2512(서열번호 2)의 아미노산 서열의 치환 돌연변이 펩티드를 설명하며, 이는 단백질 S 결합 특징을 보유한다.
일 양태에서, 본 발명의 펩티드는 60 개 미만의 아미노산, 55 개 미만의 아미노산, 40 개 미만의 아미노산, 35 개 미만의 아미노산, 30 개 미만의 아미노산으로 이루어져 있다. 선택적으로, 상기 펩티드는 25 개 미만의 아미노산, 20 개 미만의 아미노산, 15 개 미만의 아미노산 또는 10 개 아미노산 미만으로 구성된다. 다양한 구현예에서, 상기 펩티드는 15-35 개의 아미노산 잔기(예를 들어, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 또는 35 개의 아미노산 잔기)를 포함한다. 일부 양태에서, 아미노산은 N-말단, 및/또는 C-말단에서 아미노산 서열 내 본 명세서에 기재된 펩티드로부터 제거된다. 그러한 펩티드 단편은 3-14개 아미노산 잔기(예컨대, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 또는 14개 아미노산 잔기)를 포함할 수 있다. 다양한 구현예에서, 본 발명의 펩티드는 이차 펩티드 도메인, 예를 들어, 다른 타겟(예컨대, 단백질 S 또는 상이한 단백질의 상이한 영역)에 결합하거나 또는 본 발명의 펩티드의 반감기 또는 안정성을 증가시키는 것과 같이 융합 또는 복합된다. 이러한 융합체 또는 복합체에서, 본 발명의 펩티드의 크기가 이차 펩티드 또는 이종성 펩티드 도메인에 배타적이다.
일 양태에서, 상기 펩티드는 추가로 펩티드의 합성, 취급, 또는 사용을 용이하게 하는 하나 이상의 아미노산을 포함하며, 상기 아미노산은 펩티드의 용해성을 증가시키는 N-말단 및/또는 C-말단의 하나 또는 두 개의 리신을 포함하지만 이에 제한되지 않는다. 적절한 융합 단백질은 하나 이상의 폴리펩티드, 폴리펩티드 단편, 또는 일반적으로 단백질 서열의 일부로서 인식되지 않는 아미노산에 연결된 본 발명의 펩티드(예컨대, 단백질 S-결합 펩티드)를 포함하는 단백질을 포함하지만 이에 제한되지 않는다. 일 양태에서, 융합 펩티드는 둘 이상의 펩티드의 전체 아미노산 서열을 포함하거나, 대안적으로, 둘 이상의 펩티드의 부분(단편)을 포함한다. 일부 양태에서, 펩티드(예컨대, 단백질 S-결합 펩티드)는 예를 들면, 다음 중 하나 이상에 사용가능하게 연결된다: 마커(marker) 단백질, 정제를 용이하게 하는 펩티드, 다량체 단백질의 형성을 촉진하는 펩티드 서열, 또는 전술된 것들 중 어느 하나의 단편. 적절한 융합 파트너는 His 태그, FLAG 태그, strep 태그, 및 myc 태그를 포함하지만 이에 제한되지 않는다.
선택적으로, 본 발명의 펩티드는 펩티드의 반감기를 증가시키는 하나 이상의 독립체(entity)와 융합된다. 반감기는 예컨대, 신장 클리어런스(renal clearance)를 방지하기 위해 단백질 S-결합 펩티드의 분자량을 증가 및/또는 nFc 수용체-매개 재사용 경로를 위한 리간드를 포함시켜 증가될 수 있다. 일 구현예에서, 본 발명의 펩티드는 알부민 폴리펩티드 또는 이들의 단편 (예컨대, 인간 혈청 알부민(HSA) 또는 소 혈청 알부민(BSA))에 융합되거나 화학적으로 접합된다. 알부민 단편은 10%, 25%, 50%, 또는 75%의 전장 알부민 단백질을 포함한다. 펩티드-알부민 컨쥬게이트의 예로는 JBS3754 (서열번호 999)이고, 이는 알부민과 컨쥬게이션된 JBS3216 (서열번호 462)이다. 또한, JBS3761은 알부민 융합체(서열번호 1005)의 예이다. 대안적으로 또는 부가적으로, 본 발명의 펩티드는 알부민 결합 도메인 또는 생체내(in vivo) 투여시 알부민에 결합하는 지방산을 포함한다. 알부민 결합 도메인의 예는 4-(p-아이오도페닐)-부타노산에서 유도된 모이어티인 "알부-태그"이다(Dumelin et al., Angew Chem Int Ed Engl 47:3196-3201 (2008)). 기타 적절한 융합 파트너는 프롤린-알라닌-세린 다량체(PASyl화) 및 항체 또는 이의 단편(예컨대, 항체의 Fc 부분)을 포함하지만 이에 제한되지 않는다.
한 구현예에서, 둘 이상의 본 발명의 펩티드가 함께 융합, 다량체화 도메인에 의해 연결, 또는 화학적 연결을 통해 부착되어 펩티드 복합체를 생성한다. 다량체의 펩티드는 동일하거나 상이할 수 있다. 따라서, 본 발명은 선택적으로 하나 이상의 연결기에 의해 부착되고, 본 명세서에 기술된 펩티드 중 어느 하나를 포함하거나 이들로 구성된 동형-이량체(즉, 두 개의 동일한 펩티드를 포함하는 이량체), 동형-다량체 (즉, 셋 이상의 동일한 펩티드를 포함하는 복합체), 이형-이량체 (즉, 두 개의 상이한 펩티드를 포함하는 이량체), 및 이형-다량체(즉, 셋 이상의 펩티드를 포함하는 복합체, 여기에서 상기 펩티드 중 적어도 두 개는 상이함)를 제공한다. 대표적인 다량체는 40 kD, 4-암(arm) PEG 모이어티를 통해 커플링된 JBS2572 (서열번호 62) 단량체의 사량체인 JBS3179 (서열번호 433)이다.
이에 관하여, 본 발명은 일차 펩티드 및 이차 펩티드를 포함하는 펩티트 복합체를 제공한다. 본 명세서에 기술된 임의의 펩티드는 펩티드 복합체를 위해 적절한 서브유닛(예컨대, 일차 펩티드 또는 이차 펩티드)이다. 일부 구현예에서, 펩티드 복합체는 25-100 아미노산, 예컨대, 30-80 아미노산, 30-60 아미노산, 또는 30-50 아미노산을 포함한다. 펩티드 복합체에 의해 매개되는 최소 하나의 단백질 S 활성(예컨대, FVa, 인지질 결합 또는 APC 공동인자 활성에 대한 단백질 S 결합)의 저해 수준은 본 발명의 다양한 구현예에서 일차 펩티드 또는 이차 펩티드(단독 또는 선택적 또는 조합)에 의해 성취되는 저해의 수준보다 더 높다. 본 명세서에 기술된 단량체 단백질 S-결합 펩티드의 기능적 특징 및 치료 및 진단 용도는 또한 본 명세서에 기술된 펩티드 복합체에도 적용될 수 있다. 유사하게, 단량체 단백질 S-결합 펩티드에 대한 개질의 설명이 또한 펩티드 복합체와 관련된다.
본 명세서의 다양한 구현예에서, 상기 펩티드 복합체의 펩티드 서브유닛(예컨대, 일차 펩티드 및 이차 펩티드)은 직접적으로 함께 융합되거나 연결기 모이어티에 의해 연결된다. 임의의 연결기 모이어티가 펩티드 복합체의 내용 중에서 사용하기 위해 적절하다. 연결기 모이어티는, 본 발명의 일부 양태에서, 이의 입체구조 중 하나로 약 1 Å 내지 약 100 Å, 예컨대, 약 5 Å 내지 약 80 Å (약 5 Å 내지 약 50Å), 약 10 Å 내지 약 70 Å (약 10 Å 내지 약 60 Å, 약 10 Å 내지 약 50 Å, 약 10 Å 내지 약 40 Å, 또는 약 10 Å 내지 약 30 Å)의 거리를 연결한다. 따라서, 연결기는 임의적으로 그의 입체구조 중 하나로 약 1 Å 내지 약 100 Å 길이, 예컨대, 약 5 Å 내지 약 50Å 또는 약 10 Å 내지 약 30 Å 길이이다. 더욱 긴 길이의 (약 100 Å를 초과하는) 연결기가 또한 포함된다. 예를 들면, 임의적으로 약 2 kDa 내지 약 60 kDa의 분자량을 가지는 생체 적합성 중합체가, 또한 펩티드 복합체에서 사용하기 위해 고려된다. 생체 적합성 중합체의 예는, PEG, PSA, 프롤린-알라닌-세린 다량체, 및 히드록시에틸 전분을 포함하지만, 이에 제한되지 않는다. 연결기 모이어티 및 반응기의 부가적인 설명이 본 명세서에 그 전체가 참조로서 포함된 국제 특허공보 제 WO 2011/143209호에 제공된다.
일 양태에서, 연결기 모이어티는 구조 Z1 -20을 포함하며, 여기서 Z는 올리고머 빌딩 블록이다. 올리고머 빌딩 블록의 예는 아미노산, 히드록시산, 에틸렌 글리콜, 프로필렌 글리콜, 또는 전술된 것들의 임의의 조합을 포함하지만, 이에 제한되지 않는다. 예를 들면, 연결기 모이어티는 선택적으로 아미노산, 디펩티드, 트리펩티드, 또는 4-20 아미노산을 포함하는 폴리펩티드이다. 일부 구현예에서, Z는 G, s, S, a, A, Bal, Gaba, Ahx, Ttds, 또는 전술된 것들의 임의의 조합이다 (가령 A, S, 또는 A 및 S의 조합을 포함하는 펩티드 십량체(ten-mer)). 필요한 경우, 연결 모이어티는 아민, 에테르, 티오에테르, 말레이미드, 디설파이드, 아미드, 에스테르, 알켄, 시클로알켄, 알킨, 트리조일, 카르바메이트, 카르보네이트, 또는 히드라존을 포함한다.
용어 "일차 펩티드" 및 "이차 펩티드"는 펩티드의 특정한 물리적 순서를 암시하는 것이 아니라, 단지 펩티드 복합체의 상이한 서브유닛을 구별하는 것으로 이해된다. 펩티드 복합체의 서브유닛은 일차 펩티드 및 이차 펩티드가 표적(예컨대, 단백질 S)과 상호작용하는 동안 다수의 배치 중 어느 하나로 연결될 수 있다. 예를 들면, 일차 펩티드의 C-말단은 이차 펩티드의 N-말단에 연결되거나, 일차 펩티드의 N-말단은 이차 펩티드의 C-말단에 연결되거나, 일차 (또는 이차) 펩티드의 N- 또는 C-말단은 이차 (또는 일차) 펩티드 내 내부 부착점에 연결되거나, 또는 일차 및 이차 펩티드는 내부 부착점을 통해 연결된다(즉, 펩티드의 아미노산 서열 내에 위치한 부착점을 통하며 N- 또는 C- 말단에 연결되지 않음). 하나 초과의 연결기가 사용될 수 있고, 예컨대, 일차 연결 모이어티가 일차 펩티드의 N-말단 및 이차 펩티드의 C-말단에 부착되고, 이차 연결 모이어티(이는 동일 유형의 모이어티 또는 상이한 유형의 모이어티일 수 있음)가 일차 펩티드의 C-말단에 부착되고 이차 펩티드의 N-말단에 부착된다. 가능한 배치의 논의는 일차 및 이차 펩티드를 가리키지만, 부가적인 펩티드가 본 명세서에 기술된 바와 같은 일차 및/또는 이차 펩티드에 연결될 수 있음이 이해될 것이다.
유도체가 본 발명에 포함되며, 아미노산의 첨가, 결실, 또는 치환과는 별개인 일부 방식으로 화학적으로 변형된(modified) 펩티드를 포함한다. 이에 관하여, 본 명세서에 제공된 본 발명의 펩티드는 중합체, 지질, 기타 유기 모이어티, 및/또는 무기 모이어티와 화학적으로 결합된다. 펩티드 및 단백질 개질의 예는 Hermanson, Bioconjugate Techniques, Academic Press, (1996)에 제공되어 있다. 본 명세서에 기술된 펩티드는 선택적으로 또 다른 모이어티(예컨대, 펩티드 모이어티)에 대한 접합을 용이하게 하는 관능기를 포함한다. 예시적인 관능기는 이소티오시아네이트, 이소시아네이트, 아실 아지드, NHS 에스테르, 설포닐 클로라이드, 알데히드, 에폭시드, 옥시란, 카르보네이트, 아릴화제, 이미도에스테르, 카르보디이미드, 안하이드라이드, 알킬 할라이드 유도체(예컨대, 할로아세틸 유도체), 말레이미드, 아지리딘, 아실로일 유도체, 아릴화제, 티올-디설파이드 교환 시약(예컨대, 피리딜 디설파이드 또는 TNB 티올), 디아조알칸, 카르보일디이마다졸, N,N'-디석시닐 카르보네이트, N-히드록시석신이미딜 클로로포르메이트, 및 히드라진 유도체를 포함하지만 이에 제한되지 않는다. 말레이미드는 예를 들면, 생체내(in vivo)에서 알부민과 결합하는 단백질 S-결합 펩티드를 생성하기 위해 유용하다.
일 양태에서, 본 발명은 하나 이상의 수용성 중합체 부착물을 포함하도록 공유적으로 변형된 펩티드를 포함한다. 수용성 중합체(또는 기타 화학적 모이어티)는 임의의 아미노산 잔기에 부착되지만 일부 구현예에서 N- 또는 C-말단에 대한 부착이 바람직하다. 유용한 중합체는 PEG(예컨대, 대략 40 kD, 30 kD, 20 kD, 10, kD, 5 kD, 또는 1 kD 크기의 PEG), 폴리옥시에틸렌 글리콜, 폴리프로필렌 글리콜, 모노메톡시-폴리에틸렌 글리콜, 덱스트란, 히드록시에틸 전분, 셀룰로스, 폴리-(N-비닐 피롤리돈)-폴리에틸렌 글리콜, 프로필렌 글리콜 호모중합체, 폴리프로필렌 옥사이드/에틸렌 옥사이드 공중합체, 폴리시알산(PSA), 폴리옥시에틸화 폴리올(예컨대, 글리세롤) 및 폴리비닐 알코올, 뿐 아니라 전술한 것들 중 어느 하나의 혼합물을 포함하지만 이에 제한되지 않는다. 일 양태에서, 본 발명의 펩티드는 PEG화 펩티드이다. PEG 모이어티는 상이한 형태, 예컨대, 선형 또는 분지형으로 입수가능하다. PEG화 펩티드의 예로는 Ahx (6-aminohexanoic acid)를 통한 N-말단 및 Lys의 ε 아미노 기를 통한 C-말단에서 20 kD 선형 PEG 모이어티에 부착된 JBS3216 (서열번호 462)의 아미노산 서열을 포함하는 JBS3755 (서열번호 1000) 및 20 kD PEG 모이어티가 가지화된 JBS3757 (서열번호 1002)을 포함한다. 수용성 중합체 부착물의 추가적인 논의에 대해서는, 미국 특허 제4,640,835호; 제4,496,689호; 제4,301,144호; 제4,670,417호; 제4,791,192호; 및 제4,179,337호를 참조한다. 펩티드 반감기 또는 안정성을 개선하기 위해 유용한 기타 모이어티가 본 명세서에 기술되고 예를 들면, 알부민(선택적으로 본 발명의 펩티드에 접합되도록 변형됨), 지방산 사슬(예컨대, C14 지방산과 같은 C12-C18 지방산, 또는 oddc(octadecane dicarboxylic acid)과 같은 디카르복실 산), 항체 또는 이의 단편(예컨대, 항체의 Fc 부분), 및 프롤린-알라닌-세린 다량체를 포함한다.
또 다른 양태에서, 펩티드 유도체는 특정한 세포 유형, 조직, 및/또는 기관에 특이적인 표적화 모이어티를 포함한다. 대안적으로, 상기 펩티드는 정제, 검출, 다량체화, 상호작용 파트너와의 결합, 및 펩티드 활성의 특성화를 용이하게 하는 하나 이상의 화학적 모이어티에 연결된다. 예시적인 화학적 모이어티는 비오틴이다. 본 발명의 펩티드에 접합되기 위해 적절한 기타 모이어티는 광민감제, 염료, 형광 염료, 방사성핵종, 방사성핵종-함유 복합체, 효소, 독소, 및 세포독성제를 포함하지만 이에 제한되지 않는다. 광민감제는 예컨대, 포토프린(Photofrin), 비주다인(Visudyne), 레불란(Levulan), 포스칸(Foscan), 메트빅스(Metvix), 헥스빅스(Hexvix)?, 시스뷰(Cysview)™, 레이저피린(Laserphyrin), 안트린(Antrin), 포토클로르(Photochlor), 포토센스(Photosens), 포트렉스(Photrex), 루마칸(Lumacan), 세비라(Cevira), 비소낙(Visonac), BF-200 ALA, 및 암피넥스(Amphinex)를 포함한다. 필요한 경우, His 태그, FLAG 태그, strep 태그, 또는 myc 태그가 펩티드에 접합된다.
또한, 일 양태에서, 본 발명의 펩티드는 펩티드의 N-말단 아미노산이 아실화된다. 또다른 양태에서, 본 발명의 펩티드는 펩티드의 C-말단 아미노산이 아미드화된다. 추가적인 양태에서, 본 발명의 펩티드는 펩티드의 N-말단 아미노산이 아실화되고 펩티드의 C-말단 아미노산이 아미드화된다.
유도체는 또한 변형되거나 비-단백질형성적 아미노산 또는 변형된 연결기를 포함하는 펩티드를 포함한다(예컨대, Grant, Synthetic Peptides: A User's Guide, Oxford University Press (1992)를 참조). 변형된 아미노산은 예를 들면, 아미노 및/또는 카르복실 기가 또다른 기로 교체된 아미노산을 포함한다. 비-제한적 예는 티오아미드, 우레아, 티오우레아, 아실히드라지드, 에스테르, 올레핀, 설폰아미드, 인산 아미드, 케톤, 알코올, 보론산 아미드, 벤조디아제핀 및 기타 방향족 또는 비-방향족 헤테로시클을 포함하는 변형된 아미노산을 포함한다(Estiarte et al., Burgers Medicinal Chemistry, 6th 판, Volume 1, Part 4, John Wiley & Sons, New York (2002)를 참조). 비-단백질형성 아미노산은 β-알라닌(Bal), 노르발린(Nva), 노르류신(Nle), 4-아미노부티르산(γ-Abu), 2-아미노이소부티르산(Aib), 6-아미노헥사노산(ε-Ahx), 오르니틴(Orn), 히드록시프롤린(Hyp), 타우린, 사르코신, 시트룰린(Cit), 시스테인산(Coh), 시클로헥실알라닌(Cha), 메티오닌설폭사이드(Meo), 메티오닌설폰(Moo), 호모세린메틸에스테르(Hsm), 프로파르길글리신(Eag), 5-플루오로트립토판(5Fw), 6-플루오로트립토판(6Fw), 3´,4´-디메톡시페닐-알라닌(Ear), 3´,4´-디플루오로페닐알라닌(Dff), 4´-플루오로페닐-알라닌(Pff), 1-나프틸-알라닌(1Ni), 1-메틸트립토판(1Mw), 페니실라민(Pen), 호모세린(Hse), t-부틸글리신, t-부틸알라닌, 페닐글리신(Phg), 벤조티에닐알라닌(Bta), L-호모-시스테인(Hcy), N-메틸-페닐알라닌(Nmf), 2-티에닐알라닌(Thi), 3,3-디페닐알라닌(Ebw), 호모페닐알라닌(Hfe) 및 S-벤질-L-시스테인(Ece)을 포함하지만 이에 제한되지 않는다. 이들 및 기타 비-단백질형성 아미노산은 D- 또는 L-이성질체로서 존재할 수 있다. 변형된 연결기의 예는 유연성(flexible) 연결기 4,7,10-트리옥사-1,13-트리데칸디아민(Ttds), 글리신, 6-아미노헥사노산, 베타-알라닌(Bal), 펜티노산(Pyn), 및 Ttds, 글리신, 6-아미노헥사노산 및 Bal의 조합을 포함하지만 이에 제한되지 않는다.
본 발명의 펩티드를 구성하는 아미노산의 동족체(Homologs)는 표 1에 제시된 바와 같을 수 있다. 임의의 구현예에서, 본 발명의 펩티드 중 하나 이상의 아미노산이 동족체로 치환된다.
아미노산 예시적인 동족체/치환( homologs /substitutions)
A 2-Amino- isobutyric acid ( Aib ), b- Alanine ( Bal ), (S)-2- Propargylglycine ( Eag ), (S)- N -Methylalanine ( Nma ), 2- Aminobutyric acid (Abu), G, M, (S)-2-Amino-pentanoic acid ( Nva ), (S)- Norleucine ( Nle )
C S, A, (S)-Homo- cysteine ( Hcy ), M, L, I, V, (R)- N - Methylcysteine ( Nmc ), b- Cysteine
D E, Homoglutamic acid, g- Hydroxy - glutamic acid, g- Carboxy - glutamic acid, (S)- N -Methyl-Aspartic acid ( Nmd ), b- Aspartic acid, N, Q, Cysteic acid, b-Homoaspartic acid ( Bhd )
E D, Glu , Homoglutamic acid, g- Hydroxy - glutamic acid, g- Carboxy - glutamic acid, a- Aminoadipic acid, (S)- N -Methyl- glutamic acid ( Nme ), b- glutamic acid, Q, N, Cysteic acid, b- Homoglutamatic acid ( Bhe )
F L- Homophenylalanine ( Hfe ), (S)- N -Methyl- phenylalanine ( Nmf ), b-Phenylalanine, L- Phenylglycin ( Phg ), b- Homophenylalanine ( Bhf ), Thienylalanine, Benzothienylalanine , Bromophenylalanine , Iodophenylalanione, Chlorophenylalanine , Methylphenylalanine , Nitrophenylalanine, Y, W, Naphtylalanine , 1,2,3,4-L-tetrahydroisoquinolinecarboxylic acid (Tic)
G A, a, N -Methyl- glycine ( Nmg )
H (S)-N-Methyl- histidine ( Nmh ), 1- Methylhistidine , 3- Methylhistidine , Thienylalanine
I L, V, (S)-2-Amino-5-methyl- hexanoic acid ( Hle ), (S)-2-Amino- pentanoic acid (Nva), Nle , b- Isoleucine , (S)- N -Methyl- leucine ( Nml ), M, N-Methyl-L-isoleucine ( Nmi ), b- Homoisoleucine ( Bhi ), (S)- Cyclohexylalanine (Cha), L- Cyclohexylglycine ( Chg )
K (S)- N -Methyl-lysine ( Nmk ), R, (S)- N -Methyl- arginine ( Nmr ), b-Lysine, (S)-2,4-Diaminobutyric acid (Dab), (S)- Diaminopropionic acid ( Dap ), b-(1-Piperazinyl)-alanine, 2,6- Diamino -4- hexynoic acid, d- Hydroxy -lysine, (S)-Homo-arginine ( Har ), w - Hydroxy - norarginine , w-Amino- arginine , w-Methyl-arginine, b-(2- Pyridyl )- alanine , b-(3- Pyridyl )- alanine , 3-Amino-tyrosine, 4-Amino- phenylalanine , (S)-Homo- citrulline ( Hci ), (S)-Citrullin ( Cit ), b- Homolysine ( Bhk )
L I, V, Hle , Nle , (S)-2-Amino- pentanoic acid ( Nva ), b- Isoleucine , (S)- N -Methyl-leucine ( Nml ), M, b- Homovaline ( Bhv ), b- Homoleucine ( Bhl ), (S)-Cyclohexylalanine ( Cha )
M I, V, Hle , Nva , R, (S)-Homo- arginine ( Har ), (S)-N-Methyl- methionine ( Nmm ), Methioninesulfone, Methionine - sulphoxid (Met(O)), Nle
N (S)- N -Methyl- asparagine ( Nmn ), b- Asparagine , Q, (S)- N -Methyl- glutamine (Nmq), b- Glutamine , Cys (3- propionic acid amide)-OH, Cys ( O2 -3- propionic acid amide)-OH, b- Homoasparagine ( Bhn ), b- Homoglutamine ( Bhq )
P Azetidine -2-carboxylic acid, 4- Hydroxy -L- proline ( Hyp ), a-Methyl-methionine, 4- Hydroxy - piperidine -2-carboxylic acid, D- Pipecolic acid (Pip), a-Methyl-Pro, 3-Amino-Pro, 4-Amino-Pro
Q N, Nmn , (S)- N -Methyl- glutamine ( Nmq ), b- Glutamine , Cys (3- propionic acid amide)-OH, Cys( O2 -3- propionic acid amide)-OH, Bhn , Bhq
R (S)- N -Methyl-lysine ( Nmk ), K, (S)- N -Methyl- arginine ( Nmr ), b-Lysine, Dab, Dap, (S)- Ornithine ( Orn ), b-(1- Piperazinyl )- alanine , 2,6- Diamino -4- hexynoic acid, d- Hydroxy -lysine, Har , w- Hydroxy - norarginine , w-Amino- arginine , w-Methyl-arginine, b-(2- Pyridyl )- alanine , b-(3- Pyridyl )- alanine , 3-Amino-tyrosine, 4-Amino- phenylalanine , (S)-Homo- citrulline ( Hci ), (S)-Citrullin ( Cit ), Hle , L, (S)- Norleucine ( Nle ), M, Bhk , (S)- N -Methyl-lysine ( Nmk )
S T, homoserine ( Hse ), b- Serine , C, b- Cyano - alanine , allo - Threonine , b-Homoserine ( Bhs )
T S, Homothreonine , b- Threonine , allo - Threonine
V L, I, Hle , (S)-2-Amino- pentanoic acid ( Nva ), Nle , b- Valine , (S)- N -Methyl-valine ( Nmv ), M, Nmi , (S)- N -Methyl- leucine ( Nml ), (S)-Cyclohexylalanine ( Cha ), L- Cyclohexylglycine ( Chg )
W (S)-N-Methyl- tryptophane ( Nmw ), b- Tryptophan , F, L- Homophenylalanine (Hfe), (S)- N -Methyl- phenylalanine ( Nmf ), b- Phenylalanine , L- Phenylglycin (Phg), b- Homophenylalanine ( Bhf ), Thienylalanine , Benzothienylalanine , Bromophenylalanine, Iodophenylalanine , Chlorophenylalanine , Methylphenylalanine, Nitrophenylalanine , Y, Naphtylalanine , 1,2,3,4-L-tetrahydroisoquinolinecarboxylic acid (Tic), b- Homotyrosine ( Bhy )
Y (S)- N -Methyl-tyrosine ( Nmy ), b-Tyrosine, F, Hfe , Nmf , b- Phenylalanine , Phg , Bhf, Thienylalanine , Benzothienylalanine , Bromophenylalanine , Iodophenylalanine, Chlorophenylalanine , Methylphenylalanine , Nitrophenylalanine, W, Naphtylalanine , Tic, Bhy
일부 구현예에서 , 본 발명의 펩티드 내에 아미노산을 연결하는 펩티드(CO-NH) 결합은 역전되어 " 레트로 (retro)-변형된" 펩티드, 즉, 기준 펩티드에 비해 반대 방향(NH-CO 결합)으로 조립된 아미노산 잔기를 포함하는 펩티드를 생성한다. 상기 레트로 -변형된 펩티드는 기준 펩티드와 동일한 아미노산 키랄성(chirality)을 포함한다. "인버스( inverso )-변형된" 펩티드는 기준 펩티드와 동일한 방향으로 조립된 아미노산 잔기를 포함하지만, 아미노산의 키랄성은 뒤집어진 본 발명의 펩티드이다. 따라서, 기준 펩티드가 L-아미노산을 포함하는 경우, " 인버스 -변형된" 펩티드는 D-아미노산을 포함하며, 반대의 경우도 마찬가지이다. 인버스 -변형된 펩티드는 CO-NH 펩티드 결합을 포함한다. " 레트로 - 인버스 변형된" 펩티드는 반대 방향으로 조립되고 역전된 키랄성을 가지는 아미노산 잔기를 포함하는 펩티드를 의미한다. 레트로 - 인버스 유사체는 역전된 말단 및 펩티드 결합의 역전된 방향(즉, NH-CO)을 가지지만, 대략적으로 기준 펩티드에서 나타나는 곁사슬 위상학(topology)을 갖는다. 레트로 - 인버스 펩티드유사체(peptidomimetic)는 , 본 명세서에 참고로서 포함되는 Meziere et al, J. Immunol . , 159 , 3230-3237 (1997)에 기술된 방법을 비롯한 표준 방법을 이용하여 제조된다. 부분적인 레트로 - 인버스 펩티드는 아미노산 서열의 단지 일부만 역전되고 거울상이성질체 아미노산 잔기로 교체된 펩티드이다.
본 발명의 펩티드는 다양한 방식으로 제조된다. 일 양태에서, 상기 펩티드는 이하에 기술되는 것들을 비롯한 고체상 합성 기술에 의해 합성된다: Merrifield , J. Am. Chem . Soc . , 85 , 2149 (1963); Davis et al., Biochem . Intl . , 10 , 394-414 (1985); Larsen et al., J. Am. Chem . Soc . , 115 , 6247 (1993); Smith et al., J. Peptide Protein Res ., 44 , 183 (1994); O'Donnell et al., J. Am. Chem . Soc ., 118 , 6070 (1996); Stewart 및 Young, Solid Phase Peptide Synthesis , Freeman (1969); Finn et al., The Proteins , 3 rd ed., vol. 2, pp. 105-253 (1976); 및 Erickson et al., The Proteins , 3 rd ed., vol. 2, pp. 257-527 (1976). 본 발명은 합성 펩티드를 고려한다. 대안적으로, 본 발명의 펩티드를 코딩하는 핵산을 숙주 세포에 도입하고 이를 배양하여 펩티드를 발현하게 하여, 상기 펩티드가 재조합적으로 발현된다. 이러한 펩티드는 세포 배양물로부터 표준 단백질 정제 기술을 이용하여 정제된다.
본 발명은 또한 본 발명의 펩티드를 코딩하는 핵산 서열을 포함하는 핵산을 포괄한다. DNA 및/또는 RNA 분자를 제조하는 방법은 당해 분야에 공지이다. 필요한 경우, 펩티드 코딩 서열이 발현 벡터로 포함된다. 당해 분야의 숙련가는 이에 제한되지 않지만, 플라스미드, 플라스미드-리포솜 복합체, 및 바이러스 벡터와 같은 당해 분야에 공지인 다수의 발현 벡터 중 임의의 하나가 본 발명의 내용상 적절하다는 것을 이해할 것이다. 임의의 이들 발현 벡터는 예컨대, Sambrook et al., Molecular Cloning, a Laboratory Manual , 2d 판, Cold Spring Harb 또는 Press, Cold Spring Harbor, N.Y. (1989), 및 Ausubel et al., Current Protocols in Molecular Biology , Greene Publishing Associates and John Wiley & Sons, New York, N.Y. (1994)에 기술된 표준 재조합 DNA 기술을 이용하여 제조된다. 선택적으로, 핵산은 하나 이상의 조절 서열, 가령 프로모터(promoter), 액티베이터 (activator), 인핸서 ( enhancer ), 캡(cap) 신호, 폴리아데닐화 신호, 또는 전사 또는 해독의 조절에 관여하는 기타 신호에 작동가능하게 연결된다.
본 발명의 펩티드 (또는 펩티드 복합체) 중 어느 하나 또는 상기 펩티드를 인코딩하는 핵산은 또한 조성물(예컨대, 약학적 조성물)로 제공된다. 이에 관하여, 펩티드(또는 펩티드 복합체)는 본 명세서에 추가로 기술되는 바와 같이, 생리적으로-허용가능한(즉, 약리학적으로-허용가능한) 담체 (carrier), 완충액 , 부형제( excipient ), 또는 희석제와 함께 제형화된다 . 임의적으로 , 펩티드는 생리적으로 허용가능한 염의 형태이며, 이것은 본 발명에 의해 포괄된다. "생리적으로 허용가능한 염"은 약제학적으로 허용가능한 임의의 염을 의미한다. 적절한 염의 일부 예는 아세테이트, 히드로클로라이드 , 히드로브로마이드 , 설페이트 , 시트레이트 , 타르트레이트 , 글리콜레이트 , 및 옥살레이트를 포함한다. 필요한 경우, 조성물은 하나 이상의 추가적인 약제학적으로-효과적인 물질을 포함한다.
본 명세서에 제공된 펩티드는 바람직하게는 단백질 S에 결합하고 선택적으로 이에 제한되지 않지만 혈액 응고 캐스케이드를 하향 조절하는 활성과 같은 최소 하나의 단백질 S 활성을 저해한다. 임의의 특정한 작용 메커니즘에 얽매이지 않고, 상기 펩티드는 APC(activated Protein C), 인자 V, 또는 지질 표면에 대한 단백질 S의 결합을 (경쟁적으로 또는 분자병용적으로( allosterically )) 저해할 수 있으며, 이에 따라 단백질 S에 의한 응고의 자연적으로 발생한 저해가 제한된다. 단백질 S 활성의 감소로, FVa 및 FVIIIa 가 쉽게 분해되지 않고 FXa 가 덜 억제되어, 프로트롬빈의 트롬빈으로의 전환을 증진시킨다.
일 양태에서, 본 발명의 펩티드는 모델 및/또는 혈장 시스템에서 단백질 S 길항성 활성을 저해한다. 혈장-기반 분석의 예로는 외인성 응집 경로를 통해 개시된 단백질 S/APC-의존성 트롬빈 생성을 검사한다( Nicolaes , Blood Coagul . Fibrinolysis, 8 :28 (1997)). 단백질 S는 혈장에서 APC의 항응집 효과를 향상시킨다. 후보 펩티드의 존재에서 트롬빈 형성은 실질적으로 FVIII 또는 FIX 활성이 결여된 혈장에서 촉발된다(예컨대, 나머지 응집 인자 활성은 1% 미만이다). 트롬빈 형성은 형광성 또는 발색성 기질을 이용하여 검출할 수 있다. 트롬빈 활성을 측정하기 위한 시스템은 트롬비노스코프( Trombinoscope ) BV ( Maastricht , The Netherlands)에 의해 제공된다. 프로트롬빈 전환은 예컨대, 트롬보그래프( Thrombograph )™ ( Thermo Scientific, Waltham , MA)을 이용하여 측정되고, 수득된 데이터는 트롬비노스코프 BV 사로부터 입수가능한 트롬비노스코프 ™ 소프트웨어로 만들어진 교정 자동 트롬보그램(Calibrated Automatic Thrombogram , CAT)에 수집된다. 다양한 구현예에서 , 상기 펩티드는 단백질 S/APC-의존성 트롬빈 생성 분석에서 약 20 nM 부터 약 100 μM(예컨대, 약 40 nM 내지 약 50 μM)의 EC50 을 나타낸다.
특정 구현예에서 , 상기 단백질 S- 저해성 펩티드는 분석동안 생성된 피크 트롬빈의 양을 증가시키고 및/또는 피크 트롬빈 형성을 얻기 위해 요구되는 시간을 감소시킨다. 예를 들면, 펩티드는 FVIII 의 부재에서(예컨대, FVIII -결핍 혈장) 단백질 S-조절된 트롬빈 생성을, 정상 혈장에서의 단백질 S-의존성 트롬빈 생성 수준의 적어도 1%까지 개선한다. 일반적으로, 정상( 저해받지 않은) 혈장은 약 0.5 U/mL 내지 약 2 U/mL으로 인자 VIII을 함유한다. 따라서, 일부 경우, 단백질 S-결합 펩티드(예컨대, 단백질 S- 저해성 펩티드)는 FVIII 의 부재에서 트롬빈 형성을, 0.5 U/mL 내지 2 U/mL FVIII 의 존재에서 관찰된 수준의 적어도 약 1%까지 증진할 것이다.
다양한 양태에서, 생체내 ( in vivo ) 단백질 S 저해 활성을 규명하기 위해 펩티드가 트롬빈 결핍 또는 혈우병의 동물 모델에 투여된다. 이러한 생체내 ( in vivo ) 모델은 당해 분야에 공지되어 있고 예를 들면, 혈우병 A를 유발시키기 위해 항-FVIII 항체 투여된 마우스( Tranholm et al., Blood, 102 , 3615-3620 (2003)); 응집 인자 넉아웃 (knock-out) 모델 가령, 이에 제한되지 않지만, FVIII 넉아웃 마우스( Bi et al., Nat. Genet., 10 (1), 119-121 (1995)) 및 FIX 넉아웃 마우스(Wang et al., PNAS , 94 (21), 11563-66 (1997)); 토끼에서 유발된 혈우병-A( Shen et al., Blood, 42 (4), 509-521 (1973)); 및 채플 힐(Chapel Hill) HA 개( Lozier et al., PNAS, 99 , 12991-12996 (2002))를 포함한다.
다양한 펩티드가 마우스, 래트 , 토끼, 개, 고양이, 소, 말, 돼지, 기니피그, 및 영장류를 포함하지만 이에 제한되지 않는 임의의 공급원으로부터의 단백질 S에 결합한다. 일 구현예에서 , 펩티드는 인간 단백질 S에 결합한다. 선택적으로, 본 발명의 펩티드는 하나 초과의 종으로부터의 단백질 S에 결합한다(즉, 상기 펩티드는 복수의 종 간에 교차-반응성이다). 특정 양태에서, 펩티드는 1 x 10 -4 M 이하, 1 x 10 -5 M 이하, 1 x 10 -6 M 이하, 1 x 10 -7 M 이하, 1 x 10 -8 M 이하, 1 x 10 -9 M 이하 또는 1 x 10 -10 M 이하의 해리 상수 (K D )를 가지고 단백질 S에 결합한다.
친화성은 예를 들어 그리고 비제한적으로 , 임의의 하나, 둘, 또는 그 이상의 다양한 기술, 가령 친화성 ELISA( EC50 ) 분석, 경쟁적 ELISA( IC50 ) 분석, 경쟁적 LANCE IC50 분석 ( 예컨데 , 본 명세서에 기재된 상동성 유로퓸(homogenous europium)-기반 TR-FRET 분석) 및/또는 표면 플라스몬 공명(surface plasmon resonance, 비아코어 ™) 분석을 이용하여 측정될 수 있다.
선택적으로, ELISA-기반 친화성( EC50 ) 분석(예를 들면, 실시예 1에 기재된 분석)을 이용하는 경우, 펩티드는 1 x 10 -4 M 이하, 1 x 10 -5 M 이하, 1 x 10 -6 M 이하, 1 x 10 -7 M 이하, 1 x 10 -8 M 이하, 또는 1 x 10 -9 M 이하의 EC50 을 나타낸다. 경쟁적 ( IC50 ) ELISA 분석 또는 LANCE IC50 분석을 이용하여 특성을 규명하는 경우, 본 발명의 펩티드는 선택적으로 약 10,000 nM 이하의 IC50 을 나타낸다. 예를 들면, 펩티드는 약 5,000 nM 이하, 약 1,000 nM 이하, 또는 약 500 nM 이하의 IC50 을 나타낸다. 일 양태에서, 펩티드는 약 250 nM 이하, 약 100 nM 이하, 약 50 nM 이하, 또는 약 10 nM 이하의 IC50 을 나타낸다(예를 들어, 약 9 nM 이하, 약 8 nM 이하, 약 7 nM 이하, 약 6 nM 이하, 약 5 nM 이하, 약 4 nM 이하, 약 3 nM 이하, 약 2 nM 이하, 또는 약 1 nM 이하). 선택적으로, 경쟁적 분석에 "추적자(tracer)"(즉, 경쟁 펩티드)로서 JBS0684 (서열번호 1)를 이용한다. 따라서, 다양한 구현예에서 , 상기 펩티드는 추적자(tracer)로서 서열번호 1( JBS0684 )의 아미노산 서열로 구성된 펩티드를 이용하는 경쟁적(competitive) LANCE 분석에서 25 nM 미만, 10 nM 미만, 5 nM 미만, 3 nM 미만, 또는 1 nM 미만의 IC50 으로 인간 단백질 S에 결합한다. 예시적인 펩티드 및 이의 IC50 값은 도 1에 제공된다.
본 발명의 펩티드의 규명을 위한 또다른 적절한 분석은 k off 분석이며, 이것은 단백질 S로부터 펩티드의 방출을 검사한다. k off 분석 결과는 해리 속도 상수는 아니지만, 단백질 S를 이용한 항온처리(incubation) 기간 후 검사(test) 펩티드에 의한 단백질 S 결합으로 차단된 경쟁(competitor) 펩티드의 백분율이다. 예시적인 k off 분석은 다음의 단계를 포함한다: 1) 소정량의 검사 펩티드를 이용한 단백질 S-코팅된 마이크로적정 플레이트의 항온처리로 대략 90%의 단백질 S 점유율을 도출하는 단계; 2) 결합되지 않은 검사 펩티드의 제거 단계; 3) 단백질 S에 결합하기 위해 검사 펩티드와 경쟁하는 비오틴화 추적자(tracer) (즉, 경쟁) 펩티드(예컨대, JBS0684 )의 첨가 단계; 4) 일정 기간의 항온 처리 단계, 그동안 검사 펩티드에 의해 노출된 결합 부위가 추적자에 의해 점유됨; 5) 결합되지 않은 추적자 및 검사 펩티드의 제거 단계;, 및 6) 스트렙타비딘 - 홀스래디쉬 퍼옥시다제 (horseradish peroxidase ) 접합체를 이용하는 발색성 반응을 통해 결합된 추적자를 검출하는 단계. 도출되는 신호는 검사 펩티드에 의해 유리화된 결합부위를 의미한다. 상기 항온처리 기간 동안 단백질 S로부터 해리되지 않은 검사 펩티드는 완전히 해리된 분석 대상물( analyte )에 비해 더 약한 신호를 제공했다. 선택적으로, 상기 펩티드는 1 x 10 -3 s -1 이하, 1 x 10 -4 s -1 이하, 1 x 10 -5 s -1 이하, 1 x 10 -6 s -1 이하, 또는 1 x 10 -7 s -1 이하의 k off 로 나타난다.
모든 결합제 및 결합 분석에서와 같이, 당해 분야의 숙련가는 생물학적으로(예컨대, 치료적으로) 효과적이기 위해서 결합제가 검출가능하게 결합해야 하는 것이 아닌 많은 모이어티를 나열하는 것은 소모적이고 불필요할 것임을 인식한다. 그러므로, 용어 "특이적으로 결합함"은 단백질 S가 아닌 관련없는 대조군 단백질에 결합하는 것보다 더 큰 친화성으로 단백질 S에 결합하는 펩티드의 능력을 의미한다. 예를 들면, 펩티드는 대조군 단백질에 대한 친화성보다 적어도, 5, 10, 15, 25, 50, 100, 250, 500, 1000, 또는 10,000 배 더 큰 친화성으로 단백질 S에 결합할 수 있다. 일부 구현예에서, 펩티드는 상기 펩티드가 결합할 시 역효과를 일으킬 수 있는 인간의 단백질 또는 기타 자연 발생적 물질인 "항-표적"에 결합하는 것보다 더 큰 친화성으로 단백질 S에 결합한다. 몇몇 부류의 펩티드 또는 단백질이 잠재적인 항-표적이 된다. 단백질 S-저해성 펩티드가 혈류 및/또는 내피(endothelium)에서 이들의 활성을 발휘하기 때문에, 혈장 단백질이 잠재적인 항-표적으로 나타난다. 또한, 단백질 S는 Gla-도메인(예를 들어, GAS6(Growth Arrest Specific-6 유전자에 의해 코딩되는 단백질), 인자 VII, 인자 IX, 인자 X, 단백질 C, 단백질 Z, 및 프로트롬빈), EGF-유사 메인(예를 들어, GAS6, 인자 VII, 인자 IX, 인자 X, 단백질 C, 단백질 Z, 및 트롬보모듈린),및 라미닌 G-유사 도메인(예를 들어 GAS6)을 포함하는 다른 응고계 단백질의 부위에 높은 상동성을 갖는 도메인을 포함하는 멀티-도메인 단백질이다. 이러한 도메인을 갖는 단백질은 잠재적인 항-표적이다. 다양한 구현예에서, 인간 GAS6은 단백질 S에 대한 그의 상동성(42% 동일성, 57% 공통 서열)때문에 항-표적이다. 따라서, 일 구현예에서, 본 발명의 펩티드는 인간 GAS6와 같은 항-표적에 대한 친화성보다 최소 5, 10, 15, 25, 50 또는 100 배 더 큰 친화성으로 단백질 S에 결합한다(표면 플라즈몬 공명 분석법(예를 들어, 비아 코어)와 같은 임의의 적절한 방법을 사용하여 실험).
선택적으로, 본 발명의 펩티드는 하나 이상의 본 명세서에 기술된 요망되는 특성을 나타내고, 펩티드의 아미노산 서열은 필요한 경우 결합, 안정성, 및/또는 활성을 최적화하기 위해 변형될 수 있다. 예시적인 단백질 S-결합 펩티드는 10 μM 이하의 KD로 단백질 S에 결합하고 및/또는 항-표적에 대한 결합 친화성보다 적어도 10 배 더 큰 결합 친화성을 단백질 S에 대해 나타낸다. 대안적으로 또는 부가적으로, 상기 펩티드는 단백질 S가 보충된 단백질 S 결핍 혈장 및 APC 또는 FVIII 억제/결핍 혈장에서 (본 명세서에 기술된 분석들과 같은 임의의 적절한 분석을 통해 측정하여) 10 μM 이하의 EC50으로 트롬빈 형성을 향상하고/또는 인자 VIII 활성 부재에서 단백질 S-의존성 트롬빈 형성을 정상 인자 VIII 활성을 함유하는 혈장에서 트롬빈 형성의 수준의 최소 약 20% (예컨대, 40%)로 증진한다. 대안적으로 또는 부가적으로, 상기 펩티드는 원하는 수준의 혈장 안정성(예컨대, 50% 이상의 용량이 12 시간 후에도 혈장에 잔여함)을 성취하고 및/또는 원하는 생체내(in vivo) 반감기(예컨대, 적어도 2, 3, 4, 5, 6, 7, 8, 9, 또는 10 시간)를 나타내고, 원하는 수군의 수용성을 나타낸다. 대안적으로 또는 부가적으로, 본 발명의 펩티드는 원하는 수준의 생체이용률(bioavailability), 가령 피하 투여 이후 원하는 수준의 생체이용률(예컨대, 5%, 10%, 15%, 20%, 25%, 30%, 또는 50% 이상)을 나타내고 및/또는 생체내(in vivo) 주어진 용량에서 원하는 수준의 단백질 S-저해 활성을 나타낸다.
본 발명은 추가로 단백질 S를 저해하는 방법을 포함한다. 상기 방법은 단백질 S를 본 명세서에 기술된 펩티드와 접촉시키는 단계를 포함한다. 선택적으로, 상기 방법은 개체에게 단백질 S의 활성을 억제하기에 효과적인 양의 펩티드를 투여하는 단계를 포함한다. 모든 정도의 단백질 S 활성 저해가 고려된다. 예를 들면, 본 발명의 펩티드는 응집 캐스캐이드의 단백질 S 저해를 최소 약 5% (예컨대, 최소 약 10%, 최소 약 25%, 또는 최소 약 30%) 감소시킨다. 일부 구현예에서, 상기 펩티드는 펩티드의 부재에서의 단백질 S 활성과 비교하여, 단백질 S 활성을 최소 약 50%, 최소 약 75%, 또는 최소 약 90% 감소시킨다.
본 발명의 일 양태에서, 본 발명의 펩티드는 생체내(in vivo) 또는 시험관내(in vitro)에서 단백질 S를 검출 및/또는 정량하기 위해 사용된다. 샘플 내 단백질 S를 검출 및/또는 정량하는 예시적인 방법은 (a) 샘플을 본 발명의 펩티드와 접촉시키는 단계, 및 (b) 단백질 S에 대한 펩티드의 결합을 검출하는 단계를 포함한다. 상기 방법은 단백질 S가 적합한 진단 마커일 경우 질환의 치료 및 진단에 대해 유용하다. 펩티드-단백질 S 복합체는 직접적 또는 간접적으로 검출된다. 검출 모이어티는 생물학적 물질을 식별하기 위해 당해 분야에서 널리 사용되며 예를 들면, 염료(예컨대, 형광 염료), 방사성핵종 및 방사성핵종-함유 복합체, 및 효소를 포함한다. 검출 가능한 잔기는 선택적으로 펩티드에 부착 또는 접합된다. 일부 양태에서, 펩티드-단백질 S 결합은 간접적으로 검출된다. 이에 관하여, 펩티드는 임의적으로 펩티드-단백질 S 결합을 상당히 방해하지 않고 본 발명의 펩티드에 결합하는 상호작용 파트너와 접촉하며, 상호작용 파트너가 검출되게 된다. 예시적인 상호작용 파트너는 항체, 항원-결합 항체 단편, 안티칼린 및 항체 유사체, 앱타머, 스트렙타비딘, 아비딘, 뉴트라비딘, 및 거울상 압타머를 포함하지만 이에 제한되지 않는다. 선택적으로, 상호작용 파트너는 상호작용 파트너-펩티드 복합체의 검출을 용이하게 하기 위해 검출 모이어티를 포함한다. 상기 펩티드는 일부 구현예에서, 상호작용 파트너의 결합을 용이하게 하기 위해 변형된다. 예를 들면, 일 양태에서, 본 발명의 펩티드는 비오틴에 접합되고, 비오틴에 스트렙타비딘을 포함하는 상호작용 파트너가 결합한다. 예시적인 상호작용 파트너는 홀스래디쉬 퍼옥시다제에 융합된 스트렙타비딘을 포함하고, 이것이 예컨대, ELISA-유사 분석에서 검출된다. 대안적으로, 본 발명의 펩티드는 항체 에피토프(epitope)를 포함하도록 변형되며, 펩티드-단백질 S 복합체에 상응하는 항체의 결합이 검출된다.
펩티드-단백질 S 복합체 및 상호작용 파트너-펩티드 복합체는 다수의 방법, 가령 이에 제한되지 않지만, 생화학적 분석(예컨대, 효소 분석법), 분광학(예컨대, 광학 밀도, 형광, FRET, BRET, TR-FRET, 형광 편광법, 전기화학발광법, 또는 NMR에 기초한 검출), 양전자방출 단층촬영법(positron emission tomography, PET), 및 단일광자방출 단층촬영(single Photon Emission Computed Tomography, SPECT) 중 어느 하나를 이용하여 식별된다. 펩티드-단백질 S 복합체 또는 상호작용 파트너-펩티드 복합체의 형광 검출을 용이하게 하는 검출가능한 모이어티는 플루오레세인, 알렉사 플루오르(Alexa Fluor)? 350, 마리나 블루(Marina Blue)™, 캐스캐이드 옐로우(Cascade Yellow)™, 알렉사 플루오르? 405, 퍼시픽 블루(Pacific Blue)™, 퍼시픽 오렌지(Pacific Orange)™, 알렉사 플루오르? 430, 알렉사 플루오르? 488, 오레곤 그린(Oregon Green)? 488, 알렉사 플루오르? 500, 오레곤 그린? 514, 알렉사 플루오르? 514, 알렉사 플루오르? 532, 알렉사 플루오르? 555, 테트라메틸로다민(Tetramethylrhodamine), 알렉사 플루오르? 546, 로다민(Rhodamine) B, 로다민 레드(Rhodamine Red)™-X, 알렉사 플루오르? 568, 알렉사 플루오르? 594, 텍사스 레드(Texas Red)?, 텍사스 레드?-X, 알렉사 플루오르? 610, 알렉사 플루오르? 633, 알렉사 플루오르? 635, 알렉사 플루오르? 647, 알렉사 플루오르? 660, 알렉사 플루오르? 680, 알렉사 플루오르? 700, 알렉사 플루오르? 750, B-피코에리트린(Phycoerythrin), R-피코에리트린, 알로피코시아닌(Allophycocyanin), BODIPY?, Cy3, Cy5, TAMRA, 및 형광 단백질(GFP 및 이의 유도체)를 포함하지만 이에 제한되지 않는다.
본 발명은 또한 질환 또는 장애로 고통받거나, 질환 또는 장애로 고통받을 위험이 있는 개체를 진단하기 위한 방법을 제공하며, 여기서 상기 질환 또는 장애는 비정상적인 단백질 S 활성을 수반하거나 이에 의해 유발된다. 상기 방법은 개체에 본 발명의 펩티드를 투여하는 단계 및 단백질 S-펩티드 복합체를 검출하는 단계를 포함한다. 복합체의 검출은 상술한 바와 같이 기술된다. 복합체의 존재는 단백질 S의 존재를 나타내며, 이를 통해 단백질 S와 연관된 질환 또는 장애(예컨대, (i) 단백질 S를 저해하여 치료할 수 있거나 (ii) 단백질 S를 저해하여 개선되거나 예방될 수 있는 증상을 포함하는 질환 또는 장애)의 진단을 허용한다. 개체에 대한 펩티드의 투여를 원치 않을 경우, 생물학적 샘플은 개체로부터 수득되어, 본 명세서에 기술된 바와 같이 상기 펩티드와 접촉되고, 단백질 S-펩티드 복합체가 검출된다. 본 명세서에 기재된 펩티드를 이용하는 방법이 또한 본 명세서에 기재된 임의의 펩티드 복합체의 이용을 포함하는 것으로 이해될 것이다.
혈전, 정맥 혈전증 및 폐색전증과 같은 일부 질환 및 장애는 단백질 S 수준의 감소와 연관되어 있다. 단백질 S의 결핍은 유전이거나 또는 예컨대, 비타민 K 결핍, 와파린 치료, 임신, 감염, 및 간 질환으로부터 발생할 수 있다. 결핍을 검출하기 위해, 본 방법은 선택적으로 단백질 S를 정량하는 것을 수반한다. 생물학적 샘플에서 단백질 S가 소정의 임계치 이하이면, 상기 질환 또는 장애의 치료가 시작된다. 일부 경우, 상기 치료는 항응고제 치료(예컨대, 헤파린 또는 와파린 요법)를 포함한다.
본 명세서에 기재된 펩티드는 바람직하게는 단백질 S에 결합하고, 따라서, 생물학적 샘플(예컨대, 생물학적 액체, 가령 혈청), 발효 추출물, 조직 표본, 배양 배지, 등으로부터 단백질 S(예컨대, 재조합 단백질 S)를 정제하는데 유용하다. 또한, 상기 펩티드는 단백질 S와 상호 작용하는 단백질을 정제하는데 유용하나 예컨대, C4BP와 같은, 이에 한정되는 것은 아니다. 본 발명은 단백질 S의 상업적 생산 또는 단백질 S의 특성을 규명하는 방법에 본 발명의 펩티드를 사용하는 방법을 포함한다. 예를 들면, 본 발명은 단백질 S를 정제하는 방법을 포함한다. 상기 방법은 단백질 S를 함유하는 샘플을 본 명세서에 명시된 펩티드와 단백질 S 및 펩티드 간에 복합체를 형성하기 적절한 조건하에 접촉시키는 단계; 샘플로부터 상기 복합체를 제거하는 단계; 및, 선택적으로, 복합체를 해리시켜 단백질 S를 방출하는 단계를 포함한다. 단백질 S 및 펩티드 간에 복합체를 형성하기 적절한 예시적인 조건이 실시예에 개시된다. 일부 구현예에서, 상기 펩티드는 단백질 S의 회수를 용이하게 하기 위해 지지체, 예컨대, 고체 지지체에 고정된다. 예를 들면, 일 구현예에서, 상기 펩티드는 크로마토그래피 고정상(예컨대, 실리카, 친화성 크로마토그래피 비드(bead), 또는 크로마토그래피 수지)에 고정되고, 단백질 S-펩티드 복합체가 형성되도록 상기 고정상에 단백질 S를 포함하는 샘플이 가해지고, 샘플의 잔여분이 고정상으로부터 제거되고, 및 단백질 S가 고정상으로부터 용리된다. 이에 관하여, 본 발명의 펩티드는, 일 양태에서, 친화성 크로마토그래피 기술에 사용하기에 적절하다.
개체에서 트롬빈 형성을 증진하는 방법이 또한 제공된다. 상기 방법은 단백질 S를 저해하기 위해 효과적인 조건하에 본 명세서에 제공된 펩티드를 개체에 투여하는 단계를 포함한다. 이에 관하여, 상기 펩티드는 개체에서 트롬빈 형성을 증진하기에 효과적인 양으로 그러한 조건하에 투여된다. 본 발명의 다양한 양태에서, "응고 인자-결핍(clotting factor-deficient)"은 개체가 트롬빈 형성을 위해 요구되는 혈액 인자, 가령 FVIII, FIX, 또는 FXI 중 하나 이상의 결핍으로 고통받는 것을 의미한다. 실제로, 일 구현예에서, 개체는 FVIII이 결핍되어 있다. 응고 인자 결핍은 임상 샘플에서 인자의 양을 검사하여 식별된다. 전문가들은 응고 인자 결핍의 정도에 따라 혈우병을 분류한다. 경증 혈우병으로 고통받는 개체는 대략 5% 내지 30%의 정상적인 양(1 U/ml)의 인자 VIII 또는 인자 IX를 갖는다. 중등증 혈우병은 대략 1% 내지 5%의 정상 인자 VIII, 인자 IX, 또는 인자 XI 수준을 특징으로 하는 반면, 중증 혈우병으로 고통받는 개체는 1% 미만의 정상적인 양의 인자 VIII, 인자 IX, 또는 인자 XI을 갖는다. 결핍은 활성화된 부분적인 트롬보플라스틴 시간(activated partial thromboplastin time, APTT) 검사에 의해 간접적으로 식별될 수 있다. 본 발명은 응고 인자 결핍으로 고통받지 않는 개체에서 트롬빈 형성을 증진하는 것을 추가로 포함한다. 상기 방법은 트롬빈 형성을 증진하기에 효과적인 조건하에 본 명세서에 제공된 펩티드를 개체(예컨대, 정상, 생리적 수준의 응고 인자를 포함하는 개체)에 투여하는 단계를 포함한다.
일 양태에서, 상기 펩티드는 개체에서 혈전 형성을 증가시키기 위해 사용된다. 혈전 형성을 증가시키는 방법은 혈전 형성을 증가시키기 위해 효과적인 양으로 및 그러한 조건하에 본 명세서에 기술된 펩티드를 상기 개체에 투여하는 단계를 포함한다. 이익이 되는(예컨대, 치료적) 효과를 성취하기 위해 상기 방법이 응집 캐스케이드를 완전히 복구하는 것을 필요로 하지 않음이 이해될 것이다. 응고 인자 결핍과 연관된 증상의 발병 또는 중증도를 감소시키는 모든 트롬빈 또는 혈전 형성의 증진 또는 증가가 고려된다. 트롬빈 형성 및 혈액 응고를 촉진하는데 있어서 상기 방법의 효능을 측정하는 방법이 당해 분야에 공지이며 본 명세서에 기술된다.
본 발명은 추가로 개체에서 혈액 응고 장애를 치료하는 방법을 포함하며, 상기 방법은 하나 이상의 펩티드(또는 펩티드 복합체(들)), 가령 본 명세서에 기술된 펩티드 중 임의의 하나 이상을, 개체에서 혈액 응고 장애를 치료하기에 효과적인 양으로 및 그러한 조건하에 상기 개체에 투여하는 단계를 포함한다. "응고 장애(Coagulation disorders)"는 혈액 응고 장애 인자 활성 결핍 및 혈소판 활성 결핍으로 유발된 출혈 장애(예를 들어, 응고저하(hypocoagulation))를 포함한다. 혈액 응고 장애 인자는 인자 V (FV), FVII, FVIII, FIX, FX, FXI, FXIII, FII(저프로트롬빈빈혈증의 원인), 및 폰 빌러브란트(von Willebrand's) 인자를 포함하지만 이에 제한되지 않는다. 인자 결핍은 예를 들면, 인자의 짧아진 생체내(in vivo)-반감기, 인자의 변형된 결합 특성, 인자의 유전적 결함, 및 인자의 감소된 혈장 농도에 의해 야기된다. 응고 장애는 선천성이거나 후천성일 수 있다. 응고 장애는 또한 응고 인자에 대항하는 저해제 또는 자가면역성(예컨대, 항체)의 발생으로 유발된다. 일 예에서, 응고 장애는 혈우병 A이다. 대안적으로, 응고 장애는 혈우병 B 또는 혈우병 C이다.
혈소판 장애는 혈소판 기능 결핍 또는 순환계 내에서 비정상적으로 낮은 혈소판 수에 의해 야기된다. 낮은 혈소판 계수는 예를 들면, 저생산(underproduction), 혈소판 격리(sequestration), 또는 제어되지 않는 혈소판 파괴에 기인할 수 있다. 혈소판 감소증(Thrombocytopenia, 혈소판 결핍)은 화학요법 및 기타 약물 요법, 방사선 요법, 수술, 사고성 혈액 손실, 및 기타 질환 상태를 비롯한 다양한 이유로 인해 존재할 수 있다. 혈소판 감소증을 수반하는 예시적인 질환 상태는 이하와 같다: 재생불량성 빈혈; 특발성 또는 면역 혈소판 감소증(ITP), 가령 유방암 연관된 특발성 혈소판 감소성 자반증; HIV-연관성 ITP 및 HIV-연관성 혈전성 혈소판 감소성 자반증; 혈소판 감소증을 유발하는 전이성 종양; 전신성 홍반성 루푸스 가령 신생아 루푸스 증후군 비종; 판코니 증후군; 비타민 B12 결핍; 엽산 결핍; 메이-헤글린(May-Hegglin) 이상; 비스코트-알드리치(Wiskott-Aldrich) 증후군; 만성 간 질환; 혈소판 감소증과 연관된 골수이형성 증후군; 발작성 야간 혈뇨증; C7E3 Fab(아브식시맙(Abciximab)) 요법 후 급성 심재성 혈소판 감소증; 동종면역 혈소판 감소증 가령 모계 동종면역 혈소판 감소증; 항인지질 항체와 연관된 혈소판 감소증 및 혈전증; 자가면역 혈소판 감소증; 약물-유발성 면역 혈소판 감소증, 가령 카르보플라틴-유발성 혈소판 감소증 및 헤파린-유발성 혈소판 감소증; 태아 혈소판 감소증; 임신성 혈소판 감소증; 휴즈(Hughes') 증후군; 루포이드(lupoid) 혈소판 감소증; 사고성 및/또는 대량 혈액 손실; 골수증식성 장애; 악성 종양을 가진 환자에서 혈소판 감소증; 혈전성 혈소판 감소증 자반증, 가령 암환자에서 혈전성 혈소판 감소성 자반증/용혈성 요독 증후군과 같은 혈전성 미소혈관증 발현; 수혈후(post-transfusion) 자반증(PTP); 자가면역 용혈성 빈혈; 잠재성 공장게실천공(occult jejunal diverticulum perforation); 순수적혈구형성부전증; 자가면역 혈소판 감소증; 유행성신염; 리팜피신-연관성 급성 신부전; 파리-트루소(Paris-Trousseau) 혈소판 감소증; 신생아 동종면역 혈소판 감소증; 발작성 야간 혈뇨증; 위암에서 혈액학적 변화; 용혈성 요독 증후군(예컨대, 소아기 요독 증후군); 및 A형 간염 바이러스을 비롯한 바이러스성 감염 및 CMV-연관성 혈소판 감소증과 연관된 혈액학적 발현. 혈소판 장애는 또한 폰 빌러브란트 질환, 부종양성 혈소판 기능이상, 글란즈만(Glanzman's) 혈소판무력증, 및 베르나르-술리에(Bernard-Soulier) 질환을 포함하지만 이에 제한되지 않는다. 추가적인 출혈 장애는 외상(trauma)에 의해 유발된 출혈성 병태; 하나 이상의 접촉 인자의 결핍, 가령 FXI, FXII, 프리칼리크레인(prekallikrein), 및 고분자량 키니노겐(high molecular weight kininogen, HMWK); 비타민 K 결핍; 피브리노겐 장애, 가령 섬유소원혈증, 저섬유소원혈증, 및 이상섬유소원혈증; 및 알파2-항플라스민 결핍을 포함하지만 이에 제한되지 않는다. 일 구현예에서, 본 발명의 펩티드는 과도한 출혈, 가령 수술, 외상, 뇌내 출혈, 간 질환, 신질환, 혈소판 감소증, 혈소판 기능이상, 혈종(hematomas), 내출혈, 관절혈종, 저체온증, 월경, 임신, 및 뎅기 출혈열(Dengue hemorrhagic fever)에 의해 유발된 과도한 출혈을 치료하기 위해 사용된다. 상기 모두가 본 개시의 내용 중의 "혈액 응고 장애"로 여겨진다.
일 양태에서, 본 발명의 펩티드는 개체에서 하나 이상의 항응고제의 효과를 (전부 또는 부분적으로) 역전시키기 위해 사용된다. 수많은 항응고제가 당해 분야에 공지되어 있고 예를 들면, 헤파린; 쿠마린 유도체, 가령 와파린(warfarin) 또는 디쿠마롤(dicumarol); TFPI; AT III; 루푸스 항응고제; 선충 항응고제 펩티드(NAPc2); FVIIa 저해제; 활성-부위 차단된 FVIIa (FVIIai); 활성-부위 차단된 FIXa (FIXai); FIXa 저해제; FXa 저해제, 가령 폰다파리눅스(fondaparinux), 이드라파리눅스(idraparinux), DX-9065a, 및 라작사반(razaxaban)(DPC906); 활성-부위 차단된 FXa (FXai); FVa 또는 FVIIIa 저해제, 가령 활성화된 단백질 C(APC) 및 가용성 트롬보모듈린; 트롬빈 저해제, 가령 히루딘(hirudin), 비발리루딘(bivalirudin), 아르가트로반(argatroban), 및 지멜라가트란(ximelagatran); 및 응고 인자 (예컨대, FV, FVII, FVIII, FIX, FX, FXIII, FII, FXI, FXII, 폰 빌러브란트 인자, 프리칼리크레인, 또는 고분자량 키니노겐 (HMWK))에 결합하는 항체 또는 항체 단편을 포함한다.
본 명세서에 사용된, "치료하는(treating)" 및 "치료(treatment)"는 혈액 응고 질환와 연관된 증상의 중증도 및/또는 발병에서의 임의의 감소를 의미한다. 따라서, "치료하는" 및 "치료"는 치료적 및 예방적 조치를 포함한다. 당해 분야의 숙련가는 임의의 정도의 혈액 응고 장애 또는 이와 관련된 증상으로부터의 보호, 또는 이의 개선이 인간 환자와 같은 개체에 이익이 됨을 이해할 것이다. 환자의 삶의 질은 개체에서 증상의 중증도의 임의의 정도의 감소 및/또는 증상의 나타남의 지연에 의해 향상된다. 따라서, 상기 방법은 일 양태에서 개체가 혈액 응고 장애가 발생할 위험에 있다고 결정된 후(예컨대, 응고 인자(예컨대, FVIII, FIX, 또는 FXI)의 결핍이 검출됨) 가능하면 빠르게 또는 혈액 응고 장애(예컨대, 혈우병 A, 혈우병 B, 또는 혈우병 C)가 검출된 후 가능하면 빠르게 수행된다. 추가적인 양태에서, 펩티드는 상해 또는 수술 도중 과도한 혈액 손실에 대한, 전부 또는 부분적인 보호를 위해 투여된다.
상기의 관점에서, 본 발명은 개체의 치료를 위한 방법, 가령 단백질 S의 저해가 이익이 되는 질환의 치료를 위한 방법에 사용하기 위한 펩티드(또는 펩티드 복합체)를 제공한다. 한 양태에서, 상기 질환 또는 장애는 혈액 응고 장애이다. 개체는 질환 또는 장애로부터 고통받고 있거나 질환 또는 장애(또는 생물학적 이상반응, 가령 과도한 혈액 손실)로부터 고통받을 위험에 있다. 상기 방법은 본 발명의 펩티드(또는 펩티드 복합체)를 상기 질환 또는 장애를 전부 또는 부분적으로 치료하거나 예방하기에 효과적인 양으로 및 그러한 조건하에 상기 개체에 투여하는 단계를 포함한다. 본 발명은 추가로 의약의 제조에서 사용하기 위한 펩티드(또는 펩티드 복합체)를 제공한다. 예를 들면, 상기 펩티드(또는 펩티드 복합체)는 본 명세서에 상세하게 기술된 바와 같이 혈액 응고 장애의 치료를 위한 의약의 제조에 사용될 수 있다.
일부 구현예에서, 본 발명의 펩티드 복합체 또는 펩티드를 코딩하는 핵산 서열을 포함하는 핵산을 개체에 투여하는 것이 이익이 된다. 그러한 핵산은, 일 양태에서, 펩티드 복합체 또는 펩티드 대신에 또는 추가적으로 제공된다. 발현 벡터, 핵산 조절 서열, 투여 방법, 등이 추가로 본 명세서 및 미국 특허 공개공보 제20030045498호에 기술되어 있다.
개체(예컨대, 포유류, 가령 인간)에 투여되는 펩티드의 양 및 투여의 조건(예컨대, 투여 시간, 투여의 경로, 투여 계획)은 원하는 생물학적 반응을 합리적인 시간 영역 동안 일으키기에 충분하다. 순수하게 예시의 방식으로, 일 양태에서, 상기 방법은 예컨대, 약 0.1 ㎍/kg 내지 약 100 mg/kg 또는 그 이상을 투여하는 것을 포함한다. 많은 혈액 응고 장애의 만성적 속성을 고려할 때, 개체가 수주, 수달, 또는 수년에 달하는 치료 기간에 걸쳐 본 발명의 펩티드를 투여받을 것, 그리고 하루 또는 한 주에 한 회 이상의 투여를 필요로 할 것이 예상된다. 다른 구현예에서, 본 발명의 펩티드는 급성 병태(예컨대, 수술 또는 외상에 의한 출혈, 또는 응집 대체 요법을 받는 개체에서 인자 저해제/자가면역 발현)을 치료하기 위해 비교적 짧은 치료 기간, 예컨대, 1 내지 14 일 동안 투여된다.
생리적으로-허용가능한 조성물, 가령 본 명세서에 기술된 펩티드를 포함하는 약제학적 조성물을 투여하는 적절한 방법은 당해 분야에 공지되어 있다. 상황에 따라, 약제학적 조성물은 체강내에 가해지거나 주입되고, 피부 또는 점막을 통해 흡수되고, 소화되고, 흡입되고, 및/또는 순환계로 도입된다. 일 양태에서, 본 발명의 펩티드를 포함하는 조성물은 본 발명의 펩티드를 순환계로 도입하기 위해 정맥으로, 동맥으로 또는 복강내로 투여된다. 특히 저분자량 치료제와 관련하여 비-정맥 투여가 또한 적절하다. 특정한 상황에서, 본 발명의 펩티드를 포함하는 약제학적 조성물을 경구로, 국소적으로, 설하로, 질로, 직장으로, 폐로; 뇌내 (실질내(intra-parenchymal)), 뇌주위혈관내(intracerebroventricular), 근육내, 안내(intra-ocular), 문맥내, 병변내, 골수내, 척추강내, 뇌실내(intraventricular), 경피, 피하, 비강내, 요도, 또는 장 경로에 의한 주사를 통해; 서방출 시스템에 의해; 또는 이식 장치에 의해 수송하는 것이 바람직하다. 필요한 경우, 상기 펩티드는 관심의 부위를 공급하는 동맥 또는 정맥 투여를 통해, 예컨대, 다리에 수송하기 위해 대퇴동맥을 통해 국부적으로 투여된다. 일 구현예에서, 펩티드는 예를 들면, 미국 특허 제5,439,686호 및 제5,498,421호, 및 미국 특허 공개공보 제2003/0059474호, 제2003/0064033호, 제2004/0043077호, 제2005/0048127호, 제2005/0170005호, 제2005/0142205호, 제2005/142201호, 제2005/0233945호, 제2005/0147689호. 제2005/0142206호, 제2006/0024379호, 제2006/0260777호, 제2007/0207210호, 제2007/0092452호, 제2007/0281031호, 및 제2008/0026068호에 기술되는 바와 같이 미세입자로 포함된다. 대안적으로, 상기 조성물은 막, 스폰지, 또는 원하는 분자가 흡수되거나 캡슐화되는 또다른 적절한 물질의 이식을 통해 투여된다. 이식 장치가 사용되는 경우, 상기 장치는 한 양태에서 임의의 적절한 조직내로 이식되고, 원하는 분자의 수송은 다양한 양태에서 확산, 지효성(timed-release) 볼루스, 또는 연속적 투여를 통한다. 다른 양태에서, 상기 펩티드는 수술 절차 또는 상해의 치료 도중 노출된 조직에 직접 투여되거나, 수혈 절차를 통해 투여된다. 치료적 수송 접근법은 숙련된 기술자에게 공지이며, 이들 중 일부가 예를 들면, 미국 특허 제5,399,363호에 추가로 기술된다.
투여를 용이하게 하기 위해, 상기 펩티드 또는 펩티드 복합체는 한 구현예에서 담체(즉, 비히클, 어쥬번트(adjuvant), 완충액, 또는 희석제)를 포함하는 생리적으로-허용가능한 조성물로 제형화된다. 살균된, 생리적으로-허용가능한 담체는 당해 분야에 잘 공지되어 있다. 주사용 용도를 위해 적절한 예시적인 약제학적 형태는 제한없이 무균 수용액 또는 분산액 및 무균 주사 용액 또는 분산액의 즉석 제조를 위한 무균 분말을 포함한다(예를 들면, 미국 특허 제5,466,468호를 참조). 본 명세서에 제공된 펩티드를 포함하는 약제학적 조성물은 선택적으로 이러한 약제학적 조성물의 용도와 관련한 설명을 제공하는 포장 재료와 함께, 용기내에 담긴다. 일반적으로, 그러한 설명은 시약 농도를 기술하는 명시적인 표현뿐 아니라, 특정한 구현예에서, 약제학적 조성물을 재구성하기 위해 필요할 수 있는 부형제 성분 또는 희석제의 상대적인 양을 포함한다.
적절한 경우, 본 발명의 펩티드 또는 펩티드 복합체는 추가적이거나 증강된 생물학적 효과를 얻기 위한 다른 물질 및/또는 다른 치료적 양식과 조합되어 투여된다. 병용-치료제는 혈장-유래 또는 재조합 응집 인자, 혈우병 예방 치료제, 면역억제제, 혈장 인자-저해 항체 길항제(즉, 항-저해제), 항섬유소용해제, 항생제, 호르몬 요법, 항-염증제(예컨대, 비-스테로이드성 항-염증 약물(NSAID) 또는 스테로이드성 항-염증 물질), 응혈촉진제, 및 통증 완화제를 포함하지만 이에 제한되지 않는다. 일 양태에서, 상기 방법은 개체에, 예컨대, FXIII, FXII, FXI(예컨대, HEMOLEVEN? (Laboratoire francais du Fractionnement et des Biotechnologies, Les Ulis, France) 및 FXI 농축액(BioProducts Laboratory, Elstree, Hertfordshire, UK)), FX, FIX(예컨대, BENFIX? 응집 인자 IX(Wyeth, Madison, NJ); AlPHANINE? SD(Grifols, Los Angeles, CA); MONONINE?(CSL Behring, King of Prussia, PA); BEBULIN-H™(Baxter, Deerfield, IL); PROFILNINE? SD(Grifols, Los Angeles, CA); 또는 PROPLEX T™(Baxter, Deerfield, IL)), FVIII(예컨대, ADVATE™(Baxter, Deerfield, IL); HELIXATE? FS(CSL Behring, King of Prussia, PA); REFACTO?(Wyeth, Madison, NJ), XYNTHA™(Wyeth, Madison, NJ), KOGENATE? 및 KOGENATE? FS(Bayer, Pittsburgh, PA); ALPHANATE?(Grifols, Los Angeles, CA); HEMOPHIL M™(Baxter, Deerfield, IL); KOATE?-DVI(Talecris Biotherapeutics-USA, Research Triangle Park, NC); 또는 MONARC-M™(Baxter, Deerfield, IL)), FVIIa(예컨대, NOVOSEVEN? FVIIa(Novo nordisk, Princeton, NJ) 및 FVII 농축액(Baxter Bioscience, Vienna, Austria, 또는 BioProducts Laboratory, Elstree, Hertfordshire, UK)), FV, FVa, FII, 및/또는 FIII의 투여를 포함하는, 종래의 대체 인자 치료 방법에 대한 부가 요법이다. 일부 경우에, 개체는 또한 FEIBA VH 이뮤노(Immuno)™ (Baxter BioScience, Vienna, Austria)를 제공받으며, 이것은 인자 VIII 저해제 보조(bypassing) 활성을 갖는 동결-건조된 무균 인간 혈장 분획이다. FEIBA VH 이뮤노™은 대략 동일한 단위의 인자 VIII 저해제 보조 활성 및 프로트롬빈 복합체 인자들(인자 II, VII, IX, 및 X 및 단백질 C)을 함유한다. 다른 예시적인 병용-치료제는 프리칼리크레인, 고분자량 키니노겐(HMWK), 폰 빌러브란트 인자, 조직 인자, 및 트롬빈을 포함하지만 이에 제한되지 않는다. 대안적으로 또는 부가적으로, 상기 펩티드는 본 발명의 하나 이상의 상이한 펩티드와 같은 하나 이상의 상이한 단백질 S-결합 펩티드와 동시-제형화된다. 일 양태에서, 상기 펩티드의 투여는 원하는 생물학적 반응을 얻기 위해 요구되는 병용-치료제의 투여량 감소를 가능하게 한다. 또한, 선택적으로, 상기 펩티드(또는 펩티드 복합체)는 국제 특허 공개 공보 WO 2013/141965에 기재된 TFPI-결합 펩티드와 같은 TFPI(Tissue Factor Pathway Inhibitor)-결합 펩티드의 투여를 포함하는 치료 요법의 일부이다.
본 발명은 따라서 본 발명의 펩티드(또는 다중 펩티드, 또는 펩티드 복합체)를, 하나 이상의 부가적으로 적절한 물질(들)과 조합으로 개체에 투여하는 것을 포함하며, 각각은 해당 의약에 대한 적절한 용법에 따라 투여된다. 투여 전략은 상기 펩티드(또는 펩티드 복합체) 및 하나 이상의 부가적으로 적절한 물질(들)의 병행 투여(즉, 실질적으로 동시적인 투여) 및 비-병행 투여(즉, 중복되는 것과 별개로, 임의 순서로 상이한 시간에 투여)를 포함한다. 상이한 성분들이 임의적으로 동일하거나 개별적인 조성물 내, 그리고 동일하거나 상이한 투여 경로로 투여되는 것이 이해될 것이다.
본 발명은 추가로 단백질 S-결합 화합물, 가령 단백질 S-결합 펩티드를 식별하기 위한 방법을 제공한다. 일 양태에서, 상기 방법은 (a) 단백질 S-결합 펩티드 복합체를 형성하게 하는 조건 하에, 단백질 S를 본 명세서에 기술된 펩티드 및 검사 화합물(이차 펩티드일 수 있음)과 접촉시키는 단계를 포함한다. 상기 방법은 추가로 (b) 단계 (a)에서 형성된 단백질 S-펩티드 복합체를 측정하는 단계, 및 (c) 검사 화합물의 존재에서 형성된 단백질 S-펩티드 복합체의 수와 검사 화합물의 부재에서 형성된 단백질 S-펩티드 복합체의 수를 비교하는 단계를 포함한다. 검사 화합물의 부재에서 형성된 단백질 S-펩티드 복합체의 수에 비교한, 검사 화합물의 존재에서 형성된 단백질 S-펩티드 복합체의 수의 감소는 상기 검사 화합물이 단백질 S-결합 화합물임을 나타낸다. 일 양태에서, 상기 방법은 추가로 단계 (c)에서 비교를 위해 검사 화합물의 부재에서 단백질 S-펩티드 복합체를 형성하는 단계를 포함하지만, 상기 정보가 개별적으로(예컨대, 앞서 제조된 기준 표준으로부터) 얻을 수 있는 점을 고려하면 이것이 필수적이지는 않다.
단백질 S, 펩티드, 및 검사 화합물을 동시 또는 순서대로 조합하고, 선택적으로 펩티드 및/또는 검사 화합물의 첨가 전 및/또는 후에 세척 단계를 진행한다. 일 구현예에서, 단백질 S는 단백질 S-펩티드 복합체를 형성하게 하는 조건 하에 본 명세서에 기술된 펩티드와 접촉하고, 결합되지 않은 펩티드는 제거되며, 잔여하는 단백질 S-펩티드 복합체가 검사 화합물과 접촉된다. 단백질 S-펩티드 복합체로부터 펩티드의 이동이 검출되며, 상기 검사 화합물이 단백질 S-결합 화합물임을 나타낸다. 상기 이동은 예를 들면, 검사 화합물에 노출되기 전 및 후의 단백질 S-펩티드 복합체의 수를 측정하여 검출된다.
단백질 S-결합 펩티드 복합체는 샘플에서 펩티드를 검출하는 당해 분야에 공지된 검출 수단을 비롯한 임의의 적절한 검출 수단을 이용하여 검출 및/또는 측정(정량)된다. 예를 들면, 본 발명의 일 구현예에서, 본 발명의 펩티드는 시그널을 발생시키는 표지(label)를 포함한다. 예시적인 표지가 본 명세서에 기술되며 예컨대, 방사성핵종, 형광 염료, 동위원소, 효소 기질, 및 효소를 포함한다. 상기 방법은 단백질 S-펩티드 복합체에 의해 발생된 시그널을 측정하는 단계 및 검사 화합물의 존재에서 형성된 단백질 S-펩티드 복합체에 의해 발생된 신호를 검사 화합물의 부재에서 형성된 단백질 S-펩티드 복합체에 의해 발생된 신호와 비교하는 단계를 포함한다. 검사 화합물에 노출된 단백질 S-펩티드 복합체를 포함하는 샘플로부터의 시그널의 감소(검사 화합물에 노출되지 않은 단백질 S-펩티드 복합체의 유사한 샘플에 의해 발생된 시그널과 비교한 것)는 복합체 형성이 저해되거나 방해되었고, 상기 검사 화합물이 단백질 S-결합 화합물임을 나타낸다.
단백질 S-결합 화합물을 식별하는 본 발명의 방법은 특히 당해 분야에 공지된 다양한 고효율 스크리닝 기술(high throughput screening techniques)에 사용가능하다. 임의의 "검사 화합물" (예컨대, 소형 분자, 펩티드, 단백질(가령 항체 또는 이의 단편), 펩티드유사체, 또는 폴리뉴클레오타이드(DNA 또는 RNA))이 본 명세서에 기술된 방법을 이용하여 선별하기 위해 적절하다. 필요한 경우, 단백질 S 결합(및, 선택적으로, 항-단백질 S 활성)에 대해 검사 화합물의 수집물, 집단, 또는 라이브러리(library)가 본 명세서에 기술된 방법을 이용하여 선별된다. 본 발명에 의해 채택된 고효율 스크리닝 방법은 수만 내지 십만 개의 검사 화합물을 선별하도록 하는 자동 절차를 포함한다.
본 전체 문서는 통일된 개시로서 관련되는 것으로 의도되며, 본 명세서에 기술된 특징들의 모든 조합이, 상기 특징들의 조합이 본 문서의 동일한 문장, 또는 문단, 또는 섹션에 함께 나타나지 않을지라도, 고려되는 점이 이해되어야 한다. 예를 들면, 단백질 요법이 기술되는 경우, 폴리뉴클레오타이드 요법을 포함하는 구현예(단백질을 인코딩하는 폴리뉴클레오타이드/벡터를 이용함)가 구체적으로 고려되며 그 반대 또한 그러하다.
명백하게 달리 표시되지 않는 한, 본 발명의 펩티드 또는 본 발명의 방법에 대하여 본 명세서에 제공된 설명은 각각, 본 발명의 모든 펩티드 및 본 발명의 방법에 적용된다. 명확하게 달리 표시되지 않는 한, 본 발명의 펩티드 또는 이의 이용에 대하여 본 명세서에 제공된 상세한 설명은 본 발명의 펩티드 복합체에 적용된다.
또한, 본 발명은 예를 들면, 상세하게는 상기 언급된 변형보다 얼마간은 더 좁은 범위로 본 발명의 모든 구현예를 포함한다. 속(genus)으로서 기술된 본 발명의 양태와 관련하여, 모든 개체 종은 개별적으로 본 발명의 별개의 양태로 간주된다. "a" 또는 "an"으로 기술되거나 청구된 본 발명의 양태와 관련하여, 내용에서 분명하게 더욱 제한된 의미가 요구되는 경우가 아닌 한 이들 용어가 "하나 이상의"를 의미하는 것으로 이해되어야 한다. 본 발명의 양태는 특징을 "포함하는(comprising)" 으 로 기재하는 경우, 또한, 구현예는 "이루어진(consisting)" 또는 "본질적으로 이루어진(consisting essentially of)"으로 고려될 수 있다.
각각의 공보 또는 특허 출원이 구체적 및 개별적으로 참고로 포함되도록 지시된 본 명세서에 인용된 모든 출판물, 특허 및 특허 출원은 본 명세서에 참고로 인용된다.
실시예
본 발명은, 다음의 실시예를 참고하여 더욱 쉽게 이해될 것이며, 이들 실시예는 예시의 방식으로 제공되며 본 발명을 제한하는 것으로 의도되지 않는다.
실시예 1
다음 실시예는 본 명세서에 기술된 펩티드의 제조 및 선별과 단백질 S 결합 특성을 기술한다.
Fmoc 고상 합성을 이용하여 주로 아세틸화(acetylated) N-말단 및 아미드화(amidated) C-말단을 갖는 펩티드를 합성하였다. 원 생성물(Raw products)을 HPLC 로 >90%의 순도로 정제하고 TFA 염으로 동결건조하였다. 동결건조된 펩티드를 <-15℃에서 보관하였다. 단백질 S-결합 펩티드 서열을 mRNA 전시 라이브러리 및 패널 선별법을 이용하여 확인하였다. 상기 mRNA 전시 방법은 국제 특허 공보 제WO 2005/051985호 및 Liu et al., Methods in Enzymology, 318, 268-293 (2000)에 기술되어 있다. 간략하게는, 퓨로마이신 분자를 통해 mRNA는 이의 코딩되는 펩티드에 직접 연결된다. 일련의 선별 라운드 동안 펩티드-RNA 복합체를 전장 단백질 S에 노출시켜서 단백질 S-결합 후보 펩티드-RNA 복합체(Protein S-bound candidate peptide-RNA complexes)를 분리하고 농축하였다. 목적의 특성을 갖는 펩티드를 코딩하는 RNA를 역전사하여 코딩 DNA를 얻었다.
선별 라운드는 중간 및 고엄격 선별 단계뿐만 아니라 저해 항-단백질 S 항체를 기반으로 하는 경쟁적 조건을 포함하였다. 선별 과정은 점진적인 엄격의 5 회 선별 라운드로 개시하였다. 1013 랜덤 20-mer 펩티드-mRNA 복합체로 구성된 라이브러리를 상자성(paramagnetic) 스트렙타비딘 비드 상에 고정화시킨 100 nM 비오틴화 인간 단백질 S와 1 시간 동안 인큐베이션하였다. 단백질 S 비드 및 비-코팅 스트렙타비딘 대조군 비드에 대한 펩티드/mRNA 융합체(peptide/mRNA fusions)의 결합을 방사성-표지 펩티드-mRNA 복합체의 섬광 측정에 의해 모니터링하였다. 결합되지 않은 펩티드-mRNA 복합체는 4 회 세척에 의해 제거되었다. 이어서, 단백질 S-코팅 비드에 결합된 펩티드/mRNA 융합체를 증폭하여 다음 선별 라운드를 실시하였다. 단백질 S-결합 펩티드-mRNA 복합체의 점진적인 농축이 5 회 선별 라운드 동안 관찰되었다. 예를 들어, 펩티드의 고엄격 선별은 2 회 라운드에서 집단의 99%가 제거된 것으로 확인되었고, 이는 고친화성 결합체(binders)의 아집단이 남은 것이다.
친화성 테스트를 위하여, mRNA 전시(296 펩티드)에 의해 식별된 고유의 펩티드 서열을 N-말단 바이오틴화 변이체(variants)로 합성하였다.
또한, 상술한 다양한 스크리닝 방법들에서 단백질 S에 대해 검출가능한 친화성을 갖는 펩티드를 ELISA-기반 EC50 결합 방법으로 특징화하였다. 간략하게, Nunc Polysorb MTP 웰을 50 ㎕ 단백질 S(3 ㎍/㎖)로 코팅하고 2% 효모 추출물 및 0.1% 트윈80으로 블로킹하였다. 바이오틴화 펩티드를 단백질 S-코팅 웰 및 블록킹된 대조군 웰(단백질 S 제외)에서 인큐베이션하였다. 여러 세척 단계 후, 결합된 펩티드를 발색 기질인 TMB를 사용하여 스트렙타비딘-HRP로 검출하였다. 백그라운드-보정 및 정규화된 결합 시그널의 비-선형 회귀 분석에 의해 펩티드 적정 곡선으로부터 EC50 값을 구하였다. 펩티드의 친화도는 두 자리 마이크로몰부터 서브-나노몰(EC50)까지 다양하다. mRNA 디스플레이 및 스크리닝 분석에 의해 확인된 펩티드의 예로는 JBS0684 (서열번호 1) 및 JBS2512 (서열번호 2)를 포함한다.
실시예 2
본 실시예는 추가적인 단백질 S 결합 펩티드의 생성 및 단백질 S 결합의 특성을 설명한다. 또한, 본 실시예는 혈장-기반 혈우병 모델을 설명하고, 본 명세서에 기재된 펩티드의 단백질-S 저해 활성을 보여준다.
실시예 1에서 확인된 펩티드에 치환 분석을 실시하여 추가적으로 단백질 S 결합을 조사하고 향상된 활성을 갖는 펩티드를 식별하였다. 예를 들어, 모(parent) 펩티드인 JBS2512의 각 아미노산 위치를 8 개의 대표적인 아미노산 세트 (Ala, Asp, Phe, Gly, Leu, Lys, Ser, Pro)로 개별 치환하였다. 따라서, 약 160 개의 신규한 펩티드 후보가 하나의 모 펩티드로부터 생성되었다. 이러한 신규한 펩티드 후보들 각각은 모 펩티드와 비교하여 하나의 아미노산 교환이 실시되었다.
신규한 펩티드 후보들을 합성하여(순도> 60 %), 경쟁적 결합 분석법 (ELISA IC50)에서 친화성 및 트롬빈 생성 분석법(CAT)에서 활성에 대해 스크리닝하였다. 바이오틴화된 추적자(tracer) 펩티드 JBS0684를 사용하여 경쟁적(IC50) ELISA를 실시하여 후보 펩티드와 함께 단백질 S-결합에 대해 경쟁시켰다. 추적자와 경쟁하는 펩티드는 추적자(및 서로)로서 단백질 S의 동일한 영역에 결합한다. 96-웰 PolySorp 플레이트(Nunc)를 밤새 코팅 버퍼(15 mM Na2CO3, 35 mM NaHCO3, pH 9.6)에서 3 ㎍/㎖ 단백질 S로 코팅하였다. 플레이트를 세척 완충액(HNaT: 175 mM NaCl, 25 mM HEPES, 5 mM CaCl2, 0.1% Tween 80, pH 7.35)으로 3 회 세척하고, 최소 1 시간 동안 HNaT에 녹인 100 ㎕의 2% 효모 추출물로 블록킹하였다. 그 후 플레이트를 HNaT으로 3 회 세척하였다. JBS0684를 결합 ELISA에서 결정된 EC90 값에 대응하는 농도로 적용하였다. 펩티드의 경쟁자 스톡 용액(10 mM)을 HSA가 없는 HNaT에서 1/33.3으로 희석하고, 3% DMSO를 함유하는 HNaT로 일련의 1/3 희석액을 제조하였다. 추가적으로 희석액을 1:6의 비율로 비오틴 추적자 펩티드로 희석하였다(20 ㎕ 경쟁자 희석액 및 100 ㎕ 추적자 펩티드). 경쟁자 및 추적자 펩티드의 혼합물을 단백질 S-코팅 마이크로타이터 플레이트에 도포하고, 1.5 시간 동안 인큐베이션하였다. 상기 플레이트를 HNaT으로 3 회 세척하였다. 상기 마이크로타이터 플레이트에 HRP-결합 스트렙타비딘을 도포하고, 1 시간 동안 인큐베이션한 후 HNaT으로 3 회 세척하고, TMB(3,3'5,5'-Tetramethylbenzidin)를 적용하고, HRP에 의한 TMB의 이어지는 발색성 전환을 검출함으로써, 펩티드-단백질 S 결합을 검출하였다. 펩티드의 IC50 측정은 본 명세서에 제공된다(참조, 예를 들어, 표 3).
또한, CAT 분석을 사용하여 혈우병 혈장에서의 단백질 S/APC-의존성 트롬빈 생성의 개선에 대해 펩티드를 테스트하였다. 단백질 S는 혈장에서 APC의 항응고성을 향상시킨다. CAT 분석은 외인성 응고 경로를 통해 개시된 APC-매개 트롬빈 생성에 대한 단백질 S의 효과를 정량화한다(Nicolaes, Blood Coagul . Fibrinolysis, 8:28 (1997)). APC(35 nM) 및 단백질 S(25 nM)를 단백질 S-결핍 혈장에 첨가하고, 혈장 시료를 고역가 가열 불활성화된 고트 유래 항-인간 FVIII 혈장(4490 BU/ml; Baxter BioScience, Vienna, Austria; 50 BU/ml 최종 혈장 농도)으로 인큐베이션하였다. 혈장에서의 트롬빈의 형성 후에 Fluoroskan Ascent? 리더(Thermo Labsystems, Helsinki, Finland)의 CAT(calibrated automated thrombography)가 이어졌고 트롬빈 피크-높이를 통해 정량하였다. 트롬빈 생성은 피크 높이를 ~20% 감소시키는 농도에서 APC의 부재 및 존재하에서의 높은 조직 인자(TF) 농도로 결정하였다. 혈장의 단백질 S(PS)의 APC 보조인자 활성에 대해 본 명세서에 기재된 펩티드의 억제 효과는 APC로 보충된 FVIII-억제 풀링 정상 혈장에서 측정하였다. 전체(100 %) 단백질 S/APC 저해는 APC 무첨가시 트롬빈 피크의 높이이다. PS/APC 저해의 결핍(0 %)은 일정량의 APC 로 트롬빈 피크-높이 값과 상관이 있다. 2 개의 지정된 펩티드 농도 (EC50 및 EC90)에서 SD를 포함하는 야생형 대조군의 평균과 비교하여 그것의 정규화된 값으로 펩티드들을 기록하였다.
CAT 분석을 위한 예시적인 조건은 다음과 같다. 단백질 S-결핍 혈장은 35 nM APC 및 35 nM 단백질 S로 보충하였다. 스톡 APC는 10 pM TF 및 15 μM PL로 희석하였다. 동결건조된 펩티드를 5 mM 스톡 농도로 100% DMSO에 용해시키고, HNABSA5-버퍼 + 0.1% 트윈80으로 추가적으로 희석하였다. 최종 펩티드의 혈장 농도는 140 nM(EC90 야생형) 및 90 nM(EC50 야생형)이었다. 96 웰 Immulon 2HB(투명)에서, U-바닥(ThermoElectron) 플레이트에서 80 ㎕ 혈장(+CTI+Z994-5), 10 ㎕ 펩티드 희석액, 및 10 ㎕ APC-TF-PL-MIX 또는 캘리브레이터를 혼합하였다. 각 웰을 형광 기질 및 HEPES-CaCl2(100 mM)을 함유한 FluCa 시약 20 ㎕로 현탁하여 트롬빈 생성을 개시하였다. 형광 강도는 Fluoroskan Ascent? 판독기(390 nm 여기 및 460 nm의 방출 필터)를 사용하여 37℃에서 기록하였다. 결과물인 트롬빈 생성 곡선의 매개 변수는 내부 필터 및 기질 소비 효과를 보정하기 위해 Thrombinoscope™ 소프트웨어 (Thrombinoscope) 및 트롬빈 교정기를 사용하여 계산하였다(Hemker, Pathophysiol Haemost Thromb,33: 415 (2003)).
경쟁적 결합 분석 및 CAT 분석 모두를 위하여, 펩티드 후보들을 모보다 더 나은, 유사한, 또는 못한 활성을 갖는 것으로 특징화하였다. 이 분석은 세 개의 N- 말단 위치 및 13, 15 및 17 위치에 위치한 여섯 가지 부위에서 향상된 치환을 보여준다. 허용된 치환(음성적으로 활성에 영향을 미치지 않은 치환)은 1-3, 11, 13, 15, 17, 18, 및 20 위치를 포함한 여러 위치에서 확인되었다. 향상된 치환으로 선별된 펩티드들은 재-합성(순도> 90%)하여 ELISA IC50 분석을 실시하였고, 그 결과는 표 2에 제공된다.
펩티드 서열 서열번호 IC50 [nM] CAT EC50 [nM]
JBS2512 Ac-TGHVSAGWYDYNFDHYREFT-NH2 2 3.9 24
JBS2516 Ac-TAHVSAGWYDYNFDHYREFT-NH2 6 3.3 21
JBS2526 Ac-TGHVSAGWYDYNADHYREFT-NH2 16 3.6 19
JBS2528 Ac-TGHVSAGWYDYNFDAYREFT-NH2 18 5.2 23
JBS2546 Ac-TGHVSAGWYDYNFDDYREFT-NH2 36 6.8 30
JBS2552 Ac-GGHVSAGWYDYNFDHYREFT-NH2 42 5.5 24
JBS2572 Ac-TGLVSAGWYDYNFDHYREFT-NH2 62 2.5 14
JBS2582 Ac-TGHVSAGWYDYNLDHYREFT-NH2 72 2.3 15
JBS2584 Ac-TGHVSAGWYDYNFDLYREFT-NH2 74 2.7 9
JBS2586 Ac-TGHVSAGWYDYNFDHYLEFT-NH2 76 2.6 19
JBS2591 Ac-TKHVSAGWYDYNFDHYREFT-NH2 81 4.2 n.d.
JBS2592 Ac-TGKVSAGWYDYNFDHYREFT-NH2 82 5.6 68
JBS2602 Ac-TGHVSAGWYDYNKDHYREFT-NH2 92 3.4 30
JBS2604 Ac-TGHVSAGWYDYNFDKYREFT-NH2 94 4.1 19
JBS2625 Ac-TGHVSAGWYDYNFDHYFEFT-NH2 115 1.6 29
JBS2629 Ac-TPHVSAGWYDYNFDHYREFT-NH2 119 3.1 25
JBS2661 Ac-TGHVSAGWYDYNFDSYREFT-NH2 151 2.8 16
mRNA 디스플레이 선별로부터 유래된 많은 펩티드 및 치환 분석은 저 펩티드 농도의 혈장 시스템에서 단백질 S/APC 보조인자 활성의 매우 우수한 억제를 보였다. 예를 들어, JBS2512는, 단백질 S에 매우 우수한 결합 친화성 및 CAT 분석에서 낮은 EC50 값을 나타내었다. CAT-분석에서 JBS2512에 비해 1.6 배의 친화성 및 활성이 증가된 JBS2572는 3 위치에서 His에서 Leu로의 치환과 비-상동성을 갖는다. 경쟁적 결합 분석(ELISA IC50)에서, JBS2572는 2.5±0.3 nM의 IC50을 나타내었다. JBS2572는 혈우병 혈장에서 PS/APC-의존적 트롬빈 생성을 향상시켰다.
또한, 펩티드는 추적자로서 JBS0684를 사용하여(즉, 단백질 S 결합에 대한 경쟁) 경쟁성, 상동성 유로퓸(competition, homogenous europium)-기반 TR-FRET 분석(LANCE IC50 분석)으로 특징화하였다. 다음 시약을 Perkin-Elmer ProxiPlate MTP 웰에서 함께 혼합하였다(나타낸 농도는 최종 농도임): Eu-표지 단백질 S (10 nM), Ulight™ 표지 스트렙타비딘(100 nM), 추적자(JBS0684 (300 nM)), 및 펩티드(3 배 희석 단계에서 적정). 최종 부피는 50 ㎕/웰이었다. 반응 혼합물을 실온에서 1 시간 동안 인큐베이션한 후, 하기 장비 설정을 이용하여 멀티 모드 리더(SpectraMax? M5, Molecular Devices)에서 665 nm에서의 형광 방출을 기록하였다: Ex 340 nm, Em 665 nm, 지연 50 μsec, 통합 100 μsec, 검출 100. 수용성 유로퓸-표지 단백질 S에 대한 추적자 펩티드의 결합을 수용체 형광체로 표지된 스트렙타비딘으로 검출하였다(ULight™). 비-비오틴화 펩티드에 의한 단백질 S에 대한 추적자-결합의 억제는 EU-표지 단백질 S 및 ULight™-표지 스트렙타비딘 사이의 TR-FRET의 감소를 초래한다. IC50 값은 665 nm에서의 형광 방출 신호의 비선형 회귀 분석을 사용하여 일정한 추적자 농도에서의 적정 곡선으로부터 구하였다. 분자 장치 M5 리더를 사용하여 JBS2572는 49 ± 6 nM인 IC50을 나타내었다. 추가 측정은 낮은 단백질 S(2 nM) 및 추적자 농도(60 nM)의 사용을 가능하게 하는 테칸 F500 판독기를 사용하여 실시하였다; JBS2572에 대한 LANCE IC50 값은 10 nM의 범위였다.
또한, 단백질 S 친화성을 인간 전체 길이 단백질 S 및 인간 GAS6를 사용하는 비아코어(Biacore 3000 또는 Biacore T200)를 통해 결정하였다. 간단히, 1000 RU의 단백질 S 또는 GAS6을 CM5 칩에 고정화하였다. 단백질 S에 대한 단백질 S 결합 펩티드의 동력학을 검사하기 위해, 펩티드는 플로우 셀에 3 mM CaCl2, 및 1% DMSO를 함유하는 HBS-버퍼에 다양한 농도로 주입되고 상기 센서 칩 상에 고정화된 단백질과 상호작용시켰다. 상기 칩은 HBS-버퍼내의 4 M MgCl2로 재생될 수 있다. 센서그램을 랑뮤이어(Langmuir) 결합 곡선과 정합시켜 kon 및 koff를 측정하고 KD를 산출했다. 펩티드는 항-표적 GAS6에 대한 펩티드 결합 연구와 함께 단백질 S에 대한 이들의 특이도가 테스트되었다. JBS2572는 25℃에서 6 nM(kon=2.48x105 1/Ms, koff =1.48x10-3 1/s)의 단백질 S에 대한 결합의 KD를 보여주었다. 37℃에서, KD는 3.8x10-9 (4nM) (kon=1.14x106 1/Ms, koff: 4.31x10-3 1/s)이었다.
실시예 1 및 2는 단백질 S-결합 펩티드(예를 들어, 단백질 S-저해 펩티드)를생성 및 특성화하는 대표적인 방법을 제공한다. 수백개의 펩티드들은 인간 단백질 S에 결합하는 것으로 확인하였다. 예시적인 펩티드의 치환 분석은 추가적인 단백질 S-결합 펩티드를 생성하였고, 단백질 S-결합 펩티드 내 치환이 중화되고(즉, 단백질 S에 대한 친화성 유지), 어떤 경우에는 친화성이 향상되었다는 것을 보여주었다. 많은 펩티드는 해리 상수 또는 <10 μM IC50로 인간 단백질 S에 결합하였다. 또한, 실시예는 본 발명의 펩티드가 <10 μM EC50을 갖는 혈장 측정 시스템에서 단백질 S 보조인자 활성을 억제하는 것을 보여준다. 시험관내 활성은 생리적 단백질 S 농도의 존재 하에서 입증되었다.
실시예 3
본 실시예는 본 발명의 펩티드가 비-단백질 S 단백질("항-표적(anti-targets)")에 대하여 감소된 친화성을 나타낸다는 것을 보여준다.
단백질 S는 Gla-도메인(예를 들어, GAS6(Growth Arrest Specific-6 유전자에 의해 코딩되는 단백질), 인자 VII, 인자 IX, 인자 X, 단백질 C, 단백질 Z, 및 프로트롬빈), EGF-유사 메인(예를 들어, GAS6, 인자 VII, 인자 IX, 인자 X, 단백질 C, 단백질 Z, 및 트롬보모듈린),및 라미닌 G-유사 도메인(예를 들어 GAS6)을 포함하는 다른 응고계 단백질의 부위에 높은 상동성을 갖는 도메인을 포함한다. 따라서, 이러한 다른 응고계 단백질은 잠재적인 항-표적이다. 인간 GAS6은 단백질 S(42% 상동성, 57% 공통 서열)와 가장 유사하기 때문에 항-표적 결합을 결정하는 데 사용되었다.
항-표적 GAS6와의 상호 작용을 비아 코어(표면 플라즈몬 공명)로 측정하였다 (실시예 2 참조). 인간 GAS6와 펩티드의 상호 작용으로부터의 최대 시그널은 상호작용 파트너로서 단백질 S로 얻은 신호보다 훨씬 낮았다. 낮은 GAS6 결합의 동역학 분석은 오류가 발생하기 쉬우며 센서그램을 시각적으로 분석하여 항-표적 결합을 추정하였다. JBS2572는 1 μM 농도에서 GAS6에 대한 특이적 결합이 없었다. 항-표적에 대한 JBS2572의 친화성은 인간 단백질 S에 대한 펩티드의 친화성보다 최소 10 배 이하(실제로, 최소 150 배 이하)였다. 본 실시예에 의해 제공된 데이터는 본 명세서에 설명된 펩티드가 특이적으로 단백질 S에 결합한다는 것을 보여준다 .
실시예 4
인간 단백질 S에 대해 증가된 친화성을 갖는 펩티드를 JBS2572 펩티드 서열(서열번호 62)을 기반으로 하는 부분적 무작위 라이브러리로부터 수득하였다. 친화성이 높은 결합체의 선별은 실시예 1 및 2에 기재된 것과 유사한 방법을 이용하는 mRNA 디스플레이 및 스크리닝 분석법에 의해 달성되었다. 펩티드 풀에 적용된 선별 조건은 단백질 S에 대해 증가된 결합 시그널을 초래하였다. 3 회 라운드의 선별로부터 농축된 펩티드 풀을 시퀀싱화하였고, 이는, 예를 들어, JBS3216-3223 (서열번호 462-469) 및 JBS3231-3314 (서열번호 477-560)의 아미노산 서열을 수득하였다. 친화성 성숙 풀로부터 여러 가지 펩티드들이 화학적으로 변형되었다. JBS3319을 40 kD PEG 모이어티에 컨쥬게이션하여 JBS3318 (서열번호 564)를 수득하였다. 4 개 암 10 kD PEG 모이어티를 갖는 JBS3319 단량체(monomers)의 사량체(tetramer)인 JBS3321 (서열번호 567)를 수득하였다. JBS3179 (서열번호 433)는 40 kD PEG 모이어티를 포함하는 JBS3206 사량체이다. JBS3322 (서열번호 568)는 40 kD PEG 모이어티를 포함하는 JBS3206 단량체이다.
비아코어 및 LANCE IC50 분석을 통해 18 개의 대표적인 펩티드 (JBS3216, JBS3218, JBS3221, JBS3223, JBS3232, JBS3235, JBS3236, JBS3258, JBS3260, JBS3263, JBS3274, JBS3281, JBS3283, JBS3284, JBS3296, JBS3297, JBS3306, and JBS3314)에 대한 단백질 S 결합 친화성을 평가하였다. 단백질 S의 활성을 억제하는 펩티드의 능력은 CAT 분석을 통해 측정되었고, 혈장 안정성도 관찰하였다.
모든 18 펩티드의 친화성 및 활성은 모 JBS2572에 비해 향상되었다. 이 결과는 본 명세서에 기재된 펩티드의 아미노산 서열 내에서의 다양한 치환이 중화되었다는 것을 나타낸다(즉, 단백질 S에 결합하는 펩티드의 능력을 파괴하지 않음). 예를 들어, JBS2572(1-3, 13, 15, 17 및 20 위치) 및 JBS2512의 서열에서 일곱 개의 아미노산 위치에서 치환을 포함하는 JBS3216은 모 펩티드 JBS2572 (KD = 4 nM)에 비해 단백질 S(KD = 0.2 nM)에 대해 더 높은 친화성을 보여준다. 실제로, 최적의 펩티드는 1x10-4 내지 6x10-4 s-1 범위의 koff를 갖는 pM-친화성(20 배 향상)을 보여주었다. 활성 및 안정성은 1.5 배까지 향상되었다. 상술한 것과 유사한 방법을 이용한 예시적인 비아코아 결과는 표 4에 제공된다. 37℃에서 풀링된 정상 인간 혈장 및 마우스 혈장에서 혈장 안정성을 결정하였고; 표 3에 예시적인 결과를 제공한다. 또한, 안정성 분석은 인간 혈장에서 배양 24 시간 후, JBS3318, JBS3179, 및 JBS3322의 결합 활성의 80% 이상 및 JBS3216의 결합 활성의 50%가 남아 있음을 보여준다. 또한, JBS3179, JBS3318 및 JBS3322는 GAS6, 항-표적(1 μM)과 상호 작용하지 않는다는 것을 확인하였다.
펩티드 kon (1/Ms) koff (1/s) KD (nM) 마우스 혈장에서의 안정성; 4 시간[%] 인간 혈장에서의 안정성; 6 시간[%]
JBS3179 4.10E+05 1.79E-04 0.4 89 ± 13 105 ±7
JBS3318 1.52E+05 2.13E-04 1.4 102 ±20 114 ±8
JBS3322 7.80E+04 2.78E-04 3.6 91 ±26 131 ±14
JBS3216 1.14E+06 2.33E-04 0.2 66 ±23 80 ±2
JBS3263 6.29E+05 2.64E-04 0.4 56 ±6 74 ±12
JBS3283 7.35E+05 3.22E-04 0.4 94 ±6 90 ±9
JBS3306 1.00E+06 4.02E-04 0.4 80 ±14 84 ±12
JBS3321 1.58E+06 3.88E-05 0.02 94 ±12 99 ±6
중증 혈우병 A를 앓는 3 개체로부터의 혈장에서의 CAT 분석(즉, 트롬빈-기반, APC 내성 테스트)을 사용하여 이 펩티드의 저해 활성을 분석하였다. 예를 들어, JBS3179, JBS3318, 및 JBS3322는 100 nM 보다 낮은 EC50로 혈장에서 단백질 S/APC 의존 트롬빈 생성을 개선시켰다. JBS3179는 CAT 분석에서 6 nM의 EC50을 나타내었고 JBS3216도 효율적으로 인간 혈우병 A 환자 혈장에서의 CAT 분석에서 효율적으로 응고를 개선시켰다(EC50 = 85 nM). 또한, JBS3216은 여러 가지 인간이 아닌 포유 동물에서 트롬빈 생성을 향상시켰다: 사이노몰구스 원숭이, 마모셋 원숭이, 돼지, 양, 개, 토끼, 랫트, 및 마우스.
또한, JBS3179는 유용한 체내 활성을 보여주었다. 25 U/kg ADVATE와 함께 투여시 펩티드는 투여량-의존적으로 혈우병 마우스 꼬리 절단 모델에서 출혈을 감소시켰고, 비-효율적인 FVIII의 투여량과 병용 투여시 관절혈증(hemarthrosis) 혈우병 A 마우스 모델에서 상당히 관절 출혈을 감소시켰으며, 감소된 혈우병이 유도된 토끼 모델에서 생체외 트롬빈 생성을 향상시켰다.
실시예 5
본 실시예는 단백질 S에 결합하는 추가적인 펩티드를 설명하고 본 명세서에서 설명된 펩티드의 아미노산 서열 내의 가변성(variability)이 단백질 S 결합 및 억제에 대하여 중화된다는 것을 보여준다.
JBS2572 아미노산 서열에서 다수의 치환을 갖는 여러 펩티드들을 합성하였고 상술한 LANCE IC50 및 CAT 분석을 이용하여 평가하였다. 분석법의 경우, 풀링된 정상 혈장은 3 nM APC로 보충하였고, 6 pM TF 및 15 μM 인지질(DOPC/POPS 80/20)로 촉진시켰다. 스톡 APC는 24 nM(3 nM의 혈장 농도)까지 TF-PL-MIX로 희석하였다. 예시적인 결과는 표 4에 제공된다. 1, 4, 5, 13, 15 및 17 위치에 집중된 분석은, 모 서열 내 다수의 치환이 중화되는 것을 나타내고, 많은 경우 JBS2572 모 서열내 단일 치환을 갖는 펩티드에 비해 결합 친화성 및 저해 활성이 증가되었다.
펩티드 서열 서열번호 JBS2572 에서 치환 LANCE IC50 [nM] CAT
EC50 [nM]
JBS2572 Ac- TGLVSAGWYDYNFDHYREFT - NH2 62 Parent 9.7 151
JBS3186 Ac-TGLVSAGWYDYNFDTYMEFT-NH2 438 H15T, R17M 2.6 176
JBS3188 Ac-TGLVSAGWYDYNFDTYTEFT-NH2 440 H15T, R17T 2.9 155
JBS3189 Ac-TGLVSAGWYDYNFDVYTEFT-NH2 441 H15V, R17T 5.0 281
JBS3190 Ac-YGLVSAGWYDYNFDTYREFT-NH2 442 H15T, T01Y 1.6 130
JBS3191 Ac-YGLVSAGWYDYNFDVYREFT-NH2 443 H15V, T01Y 1.6 147
JBS3192 Ac-TGLVEAGWYDYNFDTYREFT-NH2 444 H15T, S05E 2.8 117
JBS3193 Ac-TGLVEAGWYDYNFDVYREFT-NH2 445 H15V, S05E 2.5 116
JBS3194 Ac-TGLVSAGWYDYNNDTYREFT-NH2 446 H15T, F13N 1.8 122
JBS3195 Ac-TGLVSAGWYDYNNDVYREFT-NH2 447 H15V, F13N 2.0 139
JBS3196 Ac-YGLVSAGWYDYNFDHYMEFT-NH2 448 R17M, T01Y 2.2 155
JBS3197 Ac-TGLVEAGWYDYNFDHYMEFT-NH2 449 R17M, S05E 6.1 146
JBS3198 Ac-TGLVSAGWYDYNNDHYMEFT-NH2 450 R17M, F13N 2.5 149
JBS3201 Ac-YGLVEAGWYDYNNDTYMEFT-NH2 453 T01Y, S05E, F13N, 15T, R17M 1.9 127
JBS3202 Ac-TGL-Tle-SAGWYDYNFDTYREFT-NH2 454 V4Tle, H15T 1.6 129
JBS3203 Ac-TGL-Tle-SAGWYDYNFDHYMEFT-NH2 455 V4Tle, R17M 1.8 127
실시예 6
본 실시예는 C4BP에 결합하는 단백질 S(PS)을 차단하는 본 명세서에 기재된 펩티드의 능력을 보여준다. C4BP는 7 개 동일 α-체인(MW 70 kDa) 및 작은 β-체인 (45 kDa)을 함유하는 문어-유사(octopus-like) 분자이다. 단백질 S는 β-체인에 결합하고, C4BP와의 단백질 S 복합체 형성은 단백질 S의 APC 보조 인자 활성을 없앤다. 칼슘 이온의 존재 하에서 단백질 S 및 C4BP의 해리 상수는 ~0.5 nM이다. 이러한 높은 친화성으로 인해, 유리(free) PS의 수준은 β-체인-함유 C4BP 에서의 몰 과량에 상응한다.
PS/C4BP 복합체에서의 본 명세서에서 설명된 펩티드의 효과를 조사하기 위하여, LANCE IC50 분석을 상술한 것과 유사한 방법을 이용하여 구축하였다. JBS2572 또는 JBS3216를 미리 형성해놓은 C4BP/PS 복합체에 첨가하였다. 복합체 농도의 변화는 TR-FRET 시그널을 기록하여 관찰하였다. 두 펩티드의 경우, C4BP/PS 복합체의 시간 및 농도 의존적 해리가 관찰되었다. JBS3216의 IC50은 0.3 nM이었고, JBS2572의 IC50은 2 nM이었다. 복합체 감소의 시간 의존성은 펩티드 모두에서 유사하였다. 100 nM JBS2572 또는 JBS3216의 존재 하에서 인큐베이션 2 시간 후, C4BP/PS 복합체는 각각 60% 및 50%로 감소하였다. 또한, 단백질 S에 대한 비오틴화 JBS2572 결합은 LANCE IC50 분석에서 C4BP에 의해 억제되었다. JBS2697를 스트렙타비딘 세파로스에 커플링하여 (a) 단백질 S(1.6 pmol) (b) C4BP (8.5 pmol) 및 (c) 단백질 S(1.6 pmol) + C4BP(8.5 pmol)과 실온에서 1 시간 동안 인큐베이션 하는 경우 풀-다운 실험은 변형된 LANCE IC50 분석의 결과를 지지하였다. JBS2697은 단백질 S 단독 실험(a) 및 C4BP-단백질 S 혼합물과의 실험(c)으로부터의 유리(free) 단백질 S 단독과 상호작용하였다.
이러한 결과는 본 명세서에 기술된 펩티드는 시간 의존적 방식으로 nM 농도로 미리 형성해둔 C4BP/PS 복합체의 분획을 감소시킬 수 있음을 보여준다. 펩티드에 의한 C4BP/PS 상호 작용의 중단(및 반대)은 C4BP/PS 복합체의 경쟁 또는 알로스테 릭 억제로부터 유래될 수 있다. 단백질 S에 대한 C4BP의 결합 부위는 0.1-0.6 nM KD로 단백질 S의 라미닌 G-도메인에 맵핑하였다. 따라서, 라미닌 G 도메인은 펩티드 및 단백질 S 사이의 상호 작용에 관여하는 것으로 보인다. 제한적 단백질 분해를 이용하는 결합 부위 맵핑 실험은 상기 관찰을 지지한다. 단백질 분해 단편의 N 말단 시퀀싱은 단백질 S의 LG1 도메인 내 펩티드-보호 영역인 것으로 확인되었고, 이는 LG1 도메인이 펩티드의 표적 결합 영역인 것을 강하게 제시한다.
SEQUENCE LISTING <110> BAXTER INTERNATIONAL INC. BAXTER HEALTHCARE SA <120> PROTEIN S INHIBITORS AND METHODS OF USE <130> 31315/46380A <150> 61/946,103 <151> 2014-02-28 <160> 2924 <170> PatentIn version 3.5 <210> 1 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal Biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1 Xaa Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 2 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 3 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 3 Ala Thr Phe Tyr Gly Thr Asn His Phe Val Glu Arg Asp Trp His Ser 1 5 10 15 Asp Tyr Tyr Gly 20 <210> 4 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 4 Trp Tyr Phe Tyr Thr Gly Asp His Glu His Ser Phe Asn Val Gly Tyr 1 5 10 15 Ala Arg Asp Thr 20 <210> 5 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 5 Ala Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 6 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 6 Thr Ala His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 7 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 7 Thr Gly Ala Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 8 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 8 Thr Gly His Ala Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 9 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 9 Thr Gly His Val Ala Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 10 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 10 Thr Gly His Val Ser Ala Ala Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 11 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 11 Thr Gly His Val Ser Ala Gly Ala Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 12 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 12 Thr Gly His Val Ser Ala Gly Trp Ala Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 13 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 13 Thr Gly His Val Ser Ala Gly Trp Tyr Ala Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 14 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 14 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Ala Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 15 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 15 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Ala Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 16 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 16 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Ala Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 17 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 17 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Ala His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 18 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 18 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Ala Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 19 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 19 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Ala 1 5 10 15 Arg Glu Phe Thr 20 <210> 20 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 20 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Ala Glu Phe Thr 20 <210> 21 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 21 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Ala Phe Thr 20 <210> 22 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 22 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Ala Thr 20 <210> 23 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 23 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Ala 20 <210> 24 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 24 Asp Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 25 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 25 Thr Asp His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 26 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 26 Thr Gly Asp Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 27 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 27 Thr Gly His Asp Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 28 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 28 Thr Gly His Val Asp Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 29 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 29 Thr Gly His Val Ser Asp Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 30 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 30 Thr Gly His Val Ser Ala Asp Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 31 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 31 Thr Gly His Val Ser Ala Gly Asp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 32 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 32 Thr Gly His Val Ser Ala Gly Trp Asp Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 33 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 33 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Asp Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 34 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 34 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asp Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 35 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 35 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asp Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 36 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 36 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Asp Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 37 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 37 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Asp 1 5 10 15 Arg Glu Phe Thr 20 <210> 38 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 38 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Asp Glu Phe Thr 20 <210> 39 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 39 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Asp Phe Thr 20 <210> 40 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 40 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Asp Thr 20 <210> 41 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 41 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Asp 20 <210> 42 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 42 Gly Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 43 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 43 Thr Gly Gly Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 44 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 44 Thr Gly His Gly Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 45 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 45 Thr Gly His Val Gly Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 46 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 46 Thr Gly His Val Ser Gly Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 47 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 47 Thr Gly His Val Ser Ala Gly Gly Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 48 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 48 Thr Gly His Val Ser Ala Gly Trp Gly Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 49 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 49 Thr Gly His Val Ser Ala Gly Trp Tyr Gly Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 50 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 50 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Gly Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 51 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 51 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Gly Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 52 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 52 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Gly Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 53 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 53 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Gly His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 54 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 54 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Gly Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 55 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 55 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Gly 1 5 10 15 Arg Glu Phe Thr 20 <210> 56 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 56 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Gly Glu Phe Thr 20 <210> 57 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 57 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Gly Phe Thr 20 <210> 58 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 58 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Gly Thr 20 <210> 59 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 59 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Gly 20 <210> 60 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 60 Leu Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 61 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 61 Thr Leu His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 62 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 62 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 63 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 63 Thr Gly His Leu Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 64 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 64 Thr Gly His Val Leu Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 65 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 65 Thr Gly His Val Ser Leu Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 66 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 66 Thr Gly His Val Ser Ala Leu Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 67 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 67 Thr Gly His Val Ser Ala Gly Leu Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 68 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 68 Thr Gly His Val Ser Ala Gly Trp Leu Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 69 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 69 Thr Gly His Val Ser Ala Gly Trp Tyr Leu Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 70 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 70 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Leu Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 71 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 71 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Leu Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 72 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 72 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Leu Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 73 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 73 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Leu His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 74 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 74 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Leu Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 75 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 75 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Leu 1 5 10 15 Arg Glu Phe Thr 20 <210> 76 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 76 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Leu Glu Phe Thr 20 <210> 77 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 77 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Leu Phe Thr 20 <210> 78 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 78 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Leu Thr 20 <210> 79 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 79 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Leu 20 <210> 80 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 80 Lys Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 81 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 81 Thr Lys His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 82 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 82 Thr Gly Lys Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 83 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 83 Thr Gly His Lys Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 84 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 84 Thr Gly His Val Lys Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 85 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 85 Thr Gly His Val Ser Lys Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 86 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 86 Thr Gly His Val Ser Ala Lys Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 87 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 87 Thr Gly His Val Ser Ala Gly Lys Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 88 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 88 Thr Gly His Val Ser Ala Gly Trp Lys Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 89 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 89 Thr Gly His Val Ser Ala Gly Trp Tyr Lys Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 90 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 90 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Lys Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 91 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 91 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Lys Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 92 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 92 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Lys Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 93 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 93 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Lys His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 94 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 94 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Lys Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 95 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 95 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Lys 1 5 10 15 Arg Glu Phe Thr 20 <210> 96 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 96 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Lys Glu Phe Thr 20 <210> 97 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 97 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Lys Phe Thr 20 <210> 98 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 98 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Lys Thr 20 <210> 99 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 99 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Lys 20 <210> 100 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 100 Phe Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 101 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 101 Thr Phe His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 102 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 102 Thr Gly Phe Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 103 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 103 Thr Gly His Phe Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 104 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 104 Thr Gly His Val Phe Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 105 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 105 Thr Gly His Val Ser Phe Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 106 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 106 Thr Gly His Val Ser Ala Phe Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 107 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 107 Thr Gly His Val Ser Ala Gly Phe Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 108 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 108 Thr Gly His Val Ser Ala Gly Trp Phe Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 109 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 109 Thr Gly His Val Ser Ala Gly Trp Tyr Phe Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 110 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 110 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Phe Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 111 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 111 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Phe Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 112 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 112 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Phe His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 113 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 113 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Phe Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 114 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 114 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Phe 1 5 10 15 Arg Glu Phe Thr 20 <210> 115 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 115 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Phe Glu Phe Thr 20 <210> 116 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 116 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Phe Phe Thr 20 <210> 117 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 117 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Phe 20 <210> 118 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 118 Pro Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 119 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 119 Thr Pro His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 120 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 120 Thr Gly Pro Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 121 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 121 Thr Gly His Pro Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 122 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 122 Thr Gly His Val Pro Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 123 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 123 Thr Gly His Val Ser Pro Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 124 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 124 Thr Gly His Val Ser Ala Pro Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 125 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 125 Thr Gly His Val Ser Ala Gly Pro Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 126 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 126 Thr Gly His Val Ser Ala Gly Trp Pro Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 127 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 127 Thr Gly His Val Ser Ala Gly Trp Tyr Pro Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 128 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 128 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Pro Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 129 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 129 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Pro Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 130 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 130 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Pro Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 131 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 131 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Pro His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 132 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 132 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Pro Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 133 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 133 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Pro 1 5 10 15 Arg Glu Phe Thr 20 <210> 134 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 134 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Pro Glu Phe Thr 20 <210> 135 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 135 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Pro Phe Thr 20 <210> 136 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 136 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Pro Thr 20 <210> 137 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 137 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Pro 20 <210> 138 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 138 Ser Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 139 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 139 Thr Ser His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 140 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 140 Thr Gly Ser Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 141 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 141 Thr Gly His Ser Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 142 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 142 Thr Gly His Val Ser Ser Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 143 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 143 Thr Gly His Val Ser Ala Ser Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 144 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 144 Thr Gly His Val Ser Ala Gly Ser Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 145 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 145 Thr Gly His Val Ser Ala Gly Trp Ser Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 146 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 146 Thr Gly His Val Ser Ala Gly Trp Tyr Ser Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 147 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 147 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Ser Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 148 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 148 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Ser Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 149 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 149 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Ser Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 150 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 150 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Ser His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 151 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 151 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Ser Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 152 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 152 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Ser 1 5 10 15 Arg Glu Phe Thr 20 <210> 153 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 153 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Ser Glu Phe Thr 20 <210> 154 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 154 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Ser Phe Thr 20 <210> 155 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 155 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Ser Thr 20 <210> 156 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 156 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Ser 20 <210> 157 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 157 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg <210> 158 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 158 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp 1 5 10 <210> 159 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 159 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr 1 5 10 <210> 160 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 160 Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr Arg Glu Phe 1 5 10 15 Thr <210> 161 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 161 Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr Arg Glu Phe Thr 1 5 10 <210> 162 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 162 Asp Tyr Asn Phe Asp His Tyr Arg Glu Phe Thr 1 5 10 <210> 163 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 163 Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr Arg 1 5 10 <210> 164 <211> 8 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> C-terminal amidation <400> 164 Gly Trp Tyr Asp Tyr Asn Phe Asp 1 5 <210> 165 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 165 Gly Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Lys Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 166 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (19)..(19) <223> C-terminal amidation <400> 166 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe <210> 167 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (18)..(18) <223> C-terminal amidation <400> 167 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu <210> 168 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 168 Thr Ala His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Asp Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 169 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 169 Thr Ala His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Leu Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 170 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 170 Gly Ala His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 171 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 171 Gly Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Leu Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 172 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 172 Gly Ala His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Leu Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 173 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 173 Gly Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Ala Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 174 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (4)..(4) <223> D-Ser <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 174 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 175 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (5)..(5) <223> D-Ala <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 175 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 176 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (7)..(7) <223> D-Ala <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 176 Thr Gly His Val Ser Ala Ala Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 177 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> D-Trp <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 177 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 178 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 178 Thr Gly His Val Glu Val Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 179 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal Biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 179 Xaa Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Ala Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 180 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal Biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 180 Xaa Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 181 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal Biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 181 Xaa Thr Pro His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 182 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal Biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 182 Xaa Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe 20 <210> 183 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> MODIFIED CYS <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 183 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr Cys 20 <210> 184 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (1)..(1) <223> Covalently bound to 400Mal-PEG <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 184 Cys Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 185 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (4)..(4) <223> Xaa is tert-Leu (Tle) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 185 Thr Gly Leu Xaa Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 186 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (5)..(5) <223> Xaa is (S)-Diaminopropionic acid (Dap) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 186 Thr Gly Leu Val Xaa Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 187 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (6)..(6) <223> Xaa is 2-amino-isobutyric acid (Aib) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 187 Thr Gly Leu Val Ser Xaa Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 188 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (6)..(6) <223> Xaa is tert-Leu (Tle) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 188 Thr Gly Leu Val Ser Xaa Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 189 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (7)..(7) <223> Xaa is 2-amino-isobutyric acid (Aib) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 189 Thr Gly Leu Val Ser Ala Xaa Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 190 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (7)..(7) <223> Xaa is N-methyl-Gly (Nmg) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 190 Thr Gly Leu Val Ser Ala Xaa Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 191 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> Xaa is L-3-Benzothienylalanine (Bta) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 191 Thr Gly Leu Val Ser Ala Gly Xaa Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 192 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> Xaa is 1-naphtylalanine (1Ni) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 192 Thr Gly Leu Val Ser Ala Gly Xaa Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 193 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> Xaa is 2-naphthylalanine (2Ni) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 193 Thr Gly Leu Val Ser Ala Gly Xaa Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 194 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (9)..(9) <223> D-Tyr <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 194 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 195 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (10)..(10) <223> D-Asp <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 195 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 196 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> D-Tyr <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 196 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 197 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (12)..(12) <223> Xaa is Asn <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 197 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 198 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (13)..(13) <223> D-Ala <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 198 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Ala Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 199 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (22)..(22) <223> Covelently bound to biotin via epsilon amino group <220> <221> MISC_FEATURE <222> (22)..(22) <223> C-terminal amidation <400> 199 Thr Gly His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr Xaa Lys 20 <210> 200 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 200 Glu Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 201 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 201 Thr Glu Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 202 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 202 Thr Gly Glu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 203 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 203 Thr Gly Leu Glu Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 204 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 204 Thr Gly Leu Val Glu Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 205 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 205 Thr Gly Leu Val Ser Glu Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 206 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 206 Thr Gly Leu Val Ser Ala Glu Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 207 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 207 Thr Gly Leu Val Ser Ala Gly Glu Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 208 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 208 Thr Gly Leu Val Ser Ala Gly Trp Glu Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 209 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 209 Thr Gly Leu Val Ser Ala Gly Trp Tyr Glu Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 210 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 210 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Glu Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 211 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 211 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Glu Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 212 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 212 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Glu Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 213 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 213 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Glu His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 214 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 214 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Glu Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 215 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 215 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Glu 1 5 10 15 Arg Glu Phe Thr 20 <210> 216 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 216 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Glu Glu Phe Thr 20 <210> 217 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 217 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Glu Thr 20 <210> 218 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 218 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Glu 20 <210> 219 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 219 His Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 220 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 220 Thr His Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 221 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 221 Thr Gly Leu His Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 222 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 222 Thr Gly Leu Val His Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 223 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 223 Thr Gly Leu Val Ser His Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 224 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 224 Thr Gly Leu Val Ser Ala His Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 225 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 225 Thr Gly Leu Val Ser Ala Gly His Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 226 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 226 Thr Gly Leu Val Ser Ala Gly Trp His Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 227 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 227 Thr Gly Leu Val Ser Ala Gly Trp Tyr His Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 228 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 228 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp His Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 229 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 229 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr His Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 230 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 230 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn His Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 231 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 231 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe His His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 232 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 232 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 233 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 233 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His His 1 5 10 15 Arg Glu Phe Thr 20 <210> 234 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 234 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 His Glu Phe Thr 20 <210> 235 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 235 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg His Phe Thr 20 <210> 236 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 236 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu His Thr 20 <210> 237 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 237 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe His 20 <210> 238 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 238 Ile Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 239 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 239 Thr Ile Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 240 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 240 Thr Gly Ile Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 241 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 241 Thr Gly Leu Ile Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 242 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 242 Thr Gly Leu Val Ile Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 243 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 243 Thr Gly Leu Val Ser Ile Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 244 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 244 Thr Gly Leu Val Ser Ala Ile Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 245 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 245 Thr Gly Leu Val Ser Ala Gly Ile Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 246 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 246 Thr Gly Leu Val Ser Ala Gly Trp Ile Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 247 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 247 Thr Gly Leu Val Ser Ala Gly Trp Tyr Ile Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 248 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 248 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Ile Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 249 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 249 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Ile Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 250 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 250 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Ile Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 251 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 251 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Ile His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 252 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 252 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Ile Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 253 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 253 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Ile 1 5 10 15 Arg Glu Phe Thr 20 <210> 254 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 254 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Ile Glu Phe Thr 20 <210> 255 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 255 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Ile Phe Thr 20 <210> 256 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 256 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Ile Thr 20 <210> 257 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 257 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Ile 20 <210> 258 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 258 Met Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 259 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 259 Thr Met Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 260 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 260 Thr Gly Met Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 261 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 261 Thr Gly Leu Met Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 262 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 262 Thr Gly Leu Val Met Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 263 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 263 Thr Gly Leu Val Ser Met Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 264 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 264 Thr Gly Leu Val Ser Ala Met Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 265 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 265 Thr Gly Leu Val Ser Ala Gly Met Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 266 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 266 Thr Gly Leu Val Ser Ala Gly Trp Met Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 267 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 267 Thr Gly Leu Val Ser Ala Gly Trp Tyr Met Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 268 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 268 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Met Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 269 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 269 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Met Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 270 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 270 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Met Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 271 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 271 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Met His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 272 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 272 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Met Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 273 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 273 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Met 1 5 10 15 Arg Glu Phe Thr 20 <210> 274 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 274 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Met Glu Phe Thr 20 <210> 275 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 275 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Met Phe Thr 20 <210> 276 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 276 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Met Thr 20 <210> 277 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 277 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Met 20 <210> 278 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 278 Asn Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 279 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 279 Thr Asn Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 280 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 280 Thr Gly Asn Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 281 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 281 Thr Gly Leu Asn Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 282 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 282 Thr Gly Leu Val Asn Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 283 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 283 Thr Gly Leu Val Ser Asn Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 284 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 284 Thr Gly Leu Val Ser Ala Asn Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 285 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 285 Thr Gly Leu Val Ser Ala Gly Asn Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 286 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 286 Thr Gly Leu Val Ser Ala Gly Trp Asn Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 287 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 287 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asn Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 288 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 288 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Asn Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 289 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 289 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asn Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 290 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 290 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asn His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 291 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 291 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Asn Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 292 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 292 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Asn 1 5 10 15 Arg Glu Phe Thr 20 <210> 293 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 293 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Asn Glu Phe Thr 20 <210> 294 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 294 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Asn Phe Thr 20 <210> 295 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 295 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Asn Thr 20 <210> 296 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 296 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Asn 20 <210> 297 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 297 Gln Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 298 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 298 Thr Gln Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 299 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 299 Thr Gly Gln Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 300 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 300 Thr Gly Leu Gln Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 301 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 301 Thr Gly Leu Val Gln Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 302 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 302 Thr Gly Leu Val Ser Gln Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 303 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 303 Thr Gly Leu Val Ser Ala Gln Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 304 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 304 Thr Gly Leu Val Ser Ala Gly Gln Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 305 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 305 Thr Gly Leu Val Ser Ala Gly Trp Gln Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 306 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 306 Thr Gly Leu Val Ser Ala Gly Trp Tyr Gln Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 307 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 307 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Gln Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 308 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 308 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Gln Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 309 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 309 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Gln Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 310 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 310 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Gln His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 311 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 311 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Gln Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 312 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 312 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Gln 1 5 10 15 Arg Glu Phe Thr 20 <210> 313 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 313 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Gln Glu Phe Thr 20 <210> 314 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 314 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Gln Phe Thr 20 <210> 315 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 315 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Gln Thr 20 <210> 316 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 316 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Gln 20 <210> 317 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 317 Arg Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 318 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 318 Thr Arg Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 319 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 319 Thr Gly Arg Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 320 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 320 Thr Gly Leu Arg Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 321 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 321 Thr Gly Leu Val Arg Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 322 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 322 Thr Gly Leu Val Ser Arg Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 323 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 323 Thr Gly Leu Val Ser Ala Arg Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 324 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 324 Thr Gly Leu Val Ser Ala Gly Arg Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 325 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 325 Thr Gly Leu Val Ser Ala Gly Trp Arg Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 326 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 326 Thr Gly Leu Val Ser Ala Gly Trp Tyr Arg Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 327 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 327 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Arg Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 328 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 328 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Arg Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 329 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 329 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Arg Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 330 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 330 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Arg His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 331 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 331 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Arg Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 332 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 332 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Arg 1 5 10 15 Arg Glu Phe Thr 20 <210> 333 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 333 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Arg Phe Thr 20 <210> 334 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 334 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Arg Thr 20 <210> 335 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 335 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Arg 20 <210> 336 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 336 Thr Thr Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 337 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 337 Thr Gly Thr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 338 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 338 Thr Gly Leu Thr Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 339 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 339 Thr Gly Leu Val Thr Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 340 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 340 Thr Gly Leu Val Ser Thr Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 341 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 341 Thr Gly Leu Val Ser Ala Thr Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 342 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 342 Thr Gly Leu Val Ser Ala Gly Thr Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 343 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 343 Thr Gly Leu Val Ser Ala Gly Trp Thr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 344 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 344 Thr Gly Leu Val Ser Ala Gly Trp Tyr Thr Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 345 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 345 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Thr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 346 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 346 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Thr Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 347 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 347 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 348 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 348 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Thr His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 349 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 349 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Thr Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 350 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 350 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Thr 1 5 10 15 Arg Glu Phe Thr 20 <210> 351 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 351 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Thr Glu Phe Thr 20 <210> 352 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 352 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Thr Phe Thr 20 <210> 353 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 353 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Thr Thr 20 <210> 354 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 354 Val Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 355 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 355 Thr Val Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 356 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 356 Thr Gly Val Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 357 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 357 Thr Gly Leu Val Val Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 358 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 358 Thr Gly Leu Val Ser Val Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 359 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 359 Thr Gly Leu Val Ser Ala Val Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 360 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 360 Thr Gly Leu Val Ser Ala Gly Val Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 361 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 361 Thr Gly Leu Val Ser Ala Gly Trp Val Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 362 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 362 Thr Gly Leu Val Ser Ala Gly Trp Tyr Val Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 363 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 363 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Val Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 364 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 364 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Val Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 365 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 365 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Val Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 366 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 366 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Val His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 367 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 367 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Val Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 368 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 368 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Val 1 5 10 15 Arg Glu Phe Thr 20 <210> 369 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 369 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Val Glu Phe Thr 20 <210> 370 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 370 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Val Phe Thr 20 <210> 371 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 371 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Val Thr 20 <210> 372 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 372 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Val 20 <210> 373 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 373 Trp Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 374 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 374 Thr Trp Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 375 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 375 Thr Gly Trp Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 376 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 376 Thr Gly Leu Trp Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 377 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 377 Thr Gly Leu Val Trp Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 378 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 378 Thr Gly Leu Val Ser Trp Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 379 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 379 Thr Gly Leu Val Ser Ala Trp Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 380 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 380 Thr Gly Leu Val Ser Ala Gly Trp Trp Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 381 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 381 Thr Gly Leu Val Ser Ala Gly Trp Tyr Trp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 382 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 382 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Trp Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 383 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 383 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Trp Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 384 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 384 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Trp Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 385 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 385 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Trp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 386 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 386 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Trp Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 387 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 387 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Trp 1 5 10 15 Arg Glu Phe Thr 20 <210> 388 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 388 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Trp Glu Phe Thr 20 <210> 389 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 389 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Trp Phe Thr 20 <210> 390 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 390 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Trp Thr 20 <210> 391 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 391 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Trp 20 <210> 392 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 392 Tyr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 393 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 393 Thr Tyr Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 394 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 394 Thr Gly Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 395 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 395 Thr Gly Leu Tyr Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 396 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 396 Thr Gly Leu Val Tyr Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 397 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 397 Thr Gly Leu Val Ser Tyr Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 398 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 398 Thr Gly Leu Val Ser Ala Tyr Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 399 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 399 Thr Gly Leu Val Ser Ala Gly Tyr Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 400 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 400 Thr Gly Leu Val Ser Ala Gly Trp Tyr Tyr Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 401 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 401 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Tyr Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 402 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 402 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Tyr Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 403 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 403 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Tyr His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 404 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 404 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Tyr Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 405 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 405 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Tyr Glu Phe Thr 20 <210> 406 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 406 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Tyr Phe Thr 20 <210> 407 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 407 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Tyr Thr 20 <210> 408 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 408 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Tyr 20 <210> 409 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> N-ethylmaleiimido Cys <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 409 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr Cys 20 <210> 410 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-ethylmaleiimido Cys <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 410 Cys Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 411 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (1)..(10) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 411 Cys Gly Leu Val Ser Ala Gly Trp Tyr Cys Asp Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 412 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (1)..(11) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 412 Cys Gly Leu Val Ser Ala Gly Trp Tyr Asp Cys Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 413 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (1)..(12) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 413 Cys Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Cys Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 414 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (1)..(13) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 414 Cys Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Cys Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 415 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (1)..(14) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 415 Cys Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Cys Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 416 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (2)..(10) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 416 Thr Cys Leu Val Ser Ala Gly Trp Tyr Cys Asp Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 417 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (2)..(11) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 417 Thr Cys Leu Val Ser Ala Gly Trp Tyr Asp Cys Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 418 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (2)..(12) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 418 Thr Cys Leu Val Ser Ala Gly Trp Tyr Asp Tyr Cys Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 419 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (2)..(13) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 419 Thr Cys Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Cys Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 420 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (2)..(14) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 420 Thr Cys Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Cys Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 421 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (5)..(13) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 421 Thr Gly Leu Val Cys Ala Gly Trp Tyr Asp Tyr Asn Cys Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 422 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (5)..(14) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 422 Thr Gly Leu Val Cys Ser Ala Gly Trp Tyr Asp Tyr Asn Cys Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 423 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (4)..(14) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 423 Thr Gly Leu Cys Val Ser Ala Gly Trp Tyr Asp Tyr Asn Cys Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 424 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (3)..(14) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 424 Thr Gly Cys Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Cys Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 425 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (1)..(13) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 425 Cys Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Cys Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 426 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (2)..(13) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 426 Thr Cys Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Cys Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 427 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (1)..(15) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 427 Cys Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Cys Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 428 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (1)..(15) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 428 Thr Cys Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Cys Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 429 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 429 Cys Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Cys Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 430 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 430 Cys Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Cys Asp His Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 431 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 431 Thr Gly Cys Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Cys Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 432 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 432 Cys Gly Leu Val Ser Ala Gly Trp Tyr Asp Cys Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 433 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Maleiimide at each end of a 40kDa 4-brached PEG reacts with C-terminal Cysteine on each of four peptides identical to this sequence to form central tetravalent core <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 433 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr Cys 20 <210> 434 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (19)..(19) <223> C-terminal amidation <400> 434 Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr Arg 1 5 10 15 Glu Phe Thr <210> 435 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (19)..(19) <223> C-terminal amidation <400> 435 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe <210> 436 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (18)..(18) <223> C-terminal amidation <400> 436 Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr Arg 1 5 10 15 Glu Phe <210> 437 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 437 Ser Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Ser Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 438 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 438 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Thr Tyr 1 5 10 15 Met Glu Phe Thr 20 <210> 439 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 439 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Val Tyr 1 5 10 15 Met Glu Phe Thr 20 <210> 440 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 440 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Thr Tyr 1 5 10 15 Thr Glu Phe Thr 20 <210> 441 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 441 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Val Tyr 1 5 10 15 Thr Glu Phe Thr 20 <210> 442 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 442 Tyr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Thr Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 443 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 443 Tyr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Val Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 444 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 444 Thr Gly Leu Val Glu Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Thr Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 445 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 445 Thr Gly Leu Val Glu Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Val Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 446 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 446 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asn Asp Thr Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 447 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 447 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asn Asp Val Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 448 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 448 Tyr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Met Glu Phe Thr 20 <210> 449 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 449 Thr Gly Leu Val Glu Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Met Glu Phe Thr 20 <210> 450 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 450 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asn Asp His Tyr 1 5 10 15 Met Glu Phe Thr 20 <210> 451 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (15)..(15) <223> Xaa is tert-Leu <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 451 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Xaa Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 452 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> Xaa is norleucine (Nle) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 452 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Xaa Glu Phe Thr 20 <210> 453 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 453 Tyr Gly Leu Val Glu Ala Gly Trp Tyr Asp Tyr Asn Asn Asp Thr Tyr 1 5 10 15 Met Glu Phe Thr 20 <210> 454 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (4)..(4) <223> Xaa is Tert-Leu (Tle) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 454 Thr Gly Leu Xaa Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Thr Tyr 1 5 10 15 Arg Glu Phe Thr 20 <210> 455 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (4)..(4) <223> Xaa is tert-Leu (Tle) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 455 Thr Gly Leu Xaa Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Met Glu Phe Thr 20 <210> 456 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (4)..(4) <223> Xaa tert-Leu (Tle) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 456 Thr Gly Leu Xaa Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Thr Tyr 1 5 10 15 Met Glu Phe Thr 20 <210> 457 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Xaa is 2-amino-3-(4-benzoylphenyl)-propanoic acid (Bpa) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 457 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr Xaa 20 <210> 458 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 458 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr Cys 20 <210> 459 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 459 Cys Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 460 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is 2-amino-3-(4-benzoylphenyl)-propanoic acid (Bpa) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 460 Xaa Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 461 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 461 Met Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr 1 5 10 15 Tyr Tyr Glu Phe Glu 20 <210> 462 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 462 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 463 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 463 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asp Asp Lys Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 464 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 464 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asn Asp Ile Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 465 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 465 Glu Tyr Thr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asn Asp Ile Tyr 1 5 10 15 Phe Glu Phe Tyr 20 <210> 466 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 466 Glu Tyr Thr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Lys Asp Thr Tyr 1 5 10 15 Glu Glu Phe Lys 20 <210> 467 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 467 Tyr Gly Ile Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Tyr 20 <210> 468 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 468 Glu Gly Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 469 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 469 Glu Ser Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Phe 20 <210> 470 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 470 Met Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr 1 5 10 15 Tyr Tyr Glu Phe Glu 20 <210> 471 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Covalently bound to 4-azido-2,3,5,6-tetrafluorobenzoic acid (Atf) which is covalently bound to biotin <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 471 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr Cys 20 <210> 472 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Covalently bound to 2-amino ethenethiol which is bound to carboxyl group of Lys; Epsilon amino of Lys bound to biotin via linker; Alpha amine of Lys bound to 4-azido-2,3,5,6-tetrafluorobenzoic acid (Atf) via linker <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 472 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr Cys 20 <210> 473 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (1)..(1) <223> Cys (Atf-Bio) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 473 Cys Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 474 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (1)..(1) <223> Cys(Atf-LC-Bio) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 474 Cys Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 475 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Xaa is 2-amino-3-(4-benzoylphenyl)-propanoic acid (Bpa) <220> <221> MISC_FEATURE <222> (22)..(22) <223> Covelently bound to biotin via epsilon amino group <220> <221> MISC_FEATURE <222> (22)..(22) <223> C-terminal amidation <400> 475 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr Xaa Lys 20 <210> 476 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is 2-amino-3-(4-benzoylphenyl)-propanoic acid (Bpa) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 476 Xaa Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His 1 5 10 15 Tyr Arg Glu Phe Thr 20 <210> 477 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 477 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Asp 20 <210> 478 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 478 Glu Tyr Tyr Val Thr Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 479 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 479 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asn Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 480 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 480 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Ala Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 481 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 481 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Met Thr Asp Thr Tyr 1 5 10 15 Thr Glu Phe Glu 20 <210> 482 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 482 Glu Tyr Tyr Val Glu Ala Gly Trp Tyr Glu Tyr Asn Thr Asp Asn Tyr 1 5 10 15 Tyr Pro Phe Glu 20 <210> 483 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 483 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Lys Tyr 1 5 10 15 Tyr Glu Phe Ile 20 <210> 484 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 484 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Arg Tyr 1 5 10 15 Tyr Glu Phe Tyr 20 <210> 485 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 485 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Thr Asn Asn Asp Arg Tyr 1 5 10 15 Tyr Glu Phe Ile 20 <210> 486 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 486 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asn Asp Ile Tyr 1 5 10 15 Tyr Glu Phe Ile 20 <210> 487 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 487 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asn Asp Ile Tyr 1 5 10 15 Leu Glu Phe Glu 20 <210> 488 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 488 Glu Tyr Tyr Val Ser Ala Gly Trp His Asp Tyr Asn Lys Asp Ile Tyr 1 5 10 15 Phe Glu Phe Phe 20 <210> 489 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 489 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asn Asp Thr Tyr 1 5 10 15 Asn Glu Phe Trp 20 <210> 490 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 490 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Ser Asp Thr Tyr 1 5 10 15 Gln Glu Phe Ile 20 <210> 491 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 491 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Ser Asp Thr Tyr 1 5 10 15 Phe Glu Phe Ile 20 <210> 492 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 492 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Glu His Asp Thr Tyr 1 5 10 15 Leu Glu Phe Tyr 20 <210> 493 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 493 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asn Tyr Glu Glu Asp Ser Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 494 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 494 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Tyr Asp Val Tyr 1 5 10 15 Thr Glu Phe Glu 20 <210> 495 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 495 Glu Gln Tyr Val Ser Ala Gly Trp Tyr Gly Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Asp 20 <210> 496 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 496 Thr Tyr Tyr Val Ser Ala Gly Trp Tyr Gly Tyr Asn Asn Asp Arg Tyr 1 5 10 15 Tyr Glu Phe Tyr 20 <210> 497 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 497 Gln Tyr Tyr Val Val Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Ser Tyr 1 5 10 15 Tyr Glu Phe Asp 20 <210> 498 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 498 Glu Glu Tyr Val Ser Ala Gly Trp Tyr Asp Met Asn Arg Asp Thr Tyr 1 5 10 15 Thr Glu Phe Tyr 20 <210> 499 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 499 Glu Tyr Thr Val Ser Ala Gly Trp Tyr Asn Tyr Asn Ala Asp Glu Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 500 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 500 Glu Tyr Thr Ile Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Met Tyr 1 5 10 15 Tyr Glu Phe Val 20 <210> 501 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 501 Glu Tyr Thr Ala Ser Ala Gly Trp Tyr Asp Tyr Asn Ser Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 502 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 502 Tyr Gly Ile Val Glu Ala Gly Trp Tyr Glu Tyr Asn Thr Asp Glu Tyr 1 5 10 15 Ile Glu Phe Trp 20 <210> 503 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 503 Tyr Gly Ile Val Ser Ala Gly Trp Tyr Glu Tyr Asn Thr Asp Ile Tyr 1 5 10 15 Glu Glu Phe Trp 20 <210> 504 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 504 Tyr Gly Ile Val Ser Ala Gly Trp Tyr Asp Met Asn Asn Asp Tyr Tyr 1 5 10 15 Phe Glu Phe Tyr 20 <210> 505 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 505 Glu Gly Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Lys Asp Ile Tyr 1 5 10 15 Leu Glu Phe Glu 20 <210> 506 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 506 Glu Gly Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Gln Asp Ile Tyr 1 5 10 15 Phe Glu Phe Ala 20 <210> 507 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 507 Glu Ser Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Ile Asp Ala Tyr 1 5 10 15 Tyr Glu Phe Tyr 20 <210> 508 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 508 Glu Ser Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Tyr 20 <210> 509 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 509 Glu Tyr Ile Val Thr Ala Gly Trp Tyr Asp Tyr Asn Lys Asp Ile Tyr 1 5 10 15 Tyr Glu Phe Lys 20 <210> 510 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 510 Glu Tyr Ile Val Glu Ala Gly Trp Tyr Asp Ile Asn Glu Asp Lys Tyr 1 5 10 15 Leu Glu Phe Tyr 20 <210> 511 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 511 Glu Tyr Ser Val Ser Ala Gly Trp Tyr Asp Tyr Tyr Asn Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Tyr 20 <210> 512 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 512 Glu Tyr Ser Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Val Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 513 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 513 Glu Ser Ile Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Glu Tyr 1 5 10 15 Tyr Glu Phe Phe 20 <210> 514 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 514 Glu Ser Ile Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Thr 20 <210> 515 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 515 Phe Gly Ile Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Pro Tyr 20 <210> 516 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 516 Phe Gly Ile Ile Ser Ala Gly Trp Tyr Asp Tyr Asn Glu Asp Ala Tyr 1 5 10 15 Ser Glu Phe Tyr 20 <210> 517 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 517 Phe Glu Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Tyr 20 <210> 518 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 518 Phe Glu Tyr Val Ile Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 His Glu Phe Asn 20 <210> 519 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 519 Ser Ala Thr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Lys Asp Val Tyr 1 5 10 15 Phe Glu Phe Glu 20 <210> 520 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 520 Glu Val Ile Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asn Asp Ile Tyr 1 5 10 15 Tyr Glu Phe Trp 20 <210> 521 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 521 Glu Val His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asn Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Gly 20 <210> 522 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 522 Glu Val Glu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asp Asp Lys Tyr 1 5 10 15 Tyr Glu Phe Gly 20 <210> 523 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 523 Glu Tyr Glu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asn Asp Val Tyr 1 5 10 15 Asn Glu Phe Tyr 20 <210> 524 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 524 Glu Tyr Phe Val Ser Ala Gly Trp Tyr Asp Tyr Asn Ala Asp Ile Tyr 1 5 10 15 Tyr Glu Phe Asp 20 <210> 525 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 525 Tyr Asn Ile Val Ser Ala Gly Trp Tyr Asp Tyr Asn Lys Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Phe 20 <210> 526 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 526 Tyr Asn Glu Val Ser Ala Gly Trp Tyr Asp Met Asn Glu Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Tyr 20 <210> 527 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 527 Tyr Val Glu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Ser Glu Phe Trp 20 <210> 528 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 528 Glu Val Glu Val Ser Ala Gly Trp Tyr Glu Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Trp 20 <210> 529 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 529 Ala Ile Tyr Val Thr Ala Gly Trp Tyr Asp Tyr Asn Asn Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Thr 20 <210> 530 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 530 His Ile Tyr Val Thr Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 His Glu Phe Glu 20 <210> 531 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 531 Arg Tyr Ile Val Ser Ala Gly Trp Tyr Asp Ile Ile Gln Asp Thr Tyr 1 5 10 15 Phe Glu Phe Tyr 20 <210> 532 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 532 Asn Tyr Ile Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asn Asp Glu Tyr 1 5 10 15 Ile Glu Phe Tyr 20 <210> 533 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 533 Glu Val Tyr Val Ser Ala Gly Trp Tyr Asn Tyr Asn Glu Asp Ala Tyr 1 5 10 15 Tyr Glu Phe Trp 20 <210> 534 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 534 Asp Val Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Glu Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Ser 20 <210> 535 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 535 Asn Met Tyr Val Ser Ala Gly Trp Tyr Asn Tyr Asn Glu Asp Thr Tyr 1 5 10 15 Glu Glu Phe Tyr 20 <210> 536 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 536 Asn Met Glu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Ser Asp Thr Tyr 1 5 10 15 His Glu Phe Trp 20 <210> 537 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 537 Glu Ala Thr Val Ser Ile Gly Trp Tyr Asp Tyr Asn Lys Asp Glu Tyr 1 5 10 15 Tyr Glu Phe Tyr 20 <210> 538 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 538 Glu Phe Ile Val Ser Ala Gly Trp Tyr Asp Tyr Asn Lys Asp Thr Tyr 1 5 10 15 Ile Glu Phe Glu 20 <210> 539 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 539 Glu Ala Met Val Ser Ala Gly Trp Tyr Asp Tyr Met Asn Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 540 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 540 Glu His Ile Val Ser Ala Gly Trp Tyr Asp Tyr Asn Met Asp Glu Tyr 1 5 10 15 Tyr Glu Phe Trp 20 <210> 541 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 541 Asp Asp Glu Val Ser Ile Gly Trp Tyr Asp Tyr Asn Thr Asp Glu Tyr 1 5 10 15 Val Glu Phe Trp 20 <210> 542 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 542 Asp Val His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Lys Asp Ile Tyr 1 5 10 15 Tyr Glu Phe Thr 20 <210> 543 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 543 Asp Asn Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Tyr 20 <210> 544 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 544 Lys Met His Val Ser Ile Gly Trp Tyr Asp Tyr Asn Asn Asp Ile Tyr 1 5 10 15 Tyr Glu Phe Tyr 20 <210> 545 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 545 Lys Val Glu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Lys Asp Val Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 546 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 546 Lys Asp Lys Val Ser Ala Gly Trp Tyr Asp Tyr Asn Ser Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Thr 20 <210> 547 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 547 Ile Ile Met Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 548 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 548 Ile Thr His Val Thr Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Ile 20 <210> 549 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 549 Val Ile Glu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Glu Asp Lys Tyr 1 5 10 15 Tyr Glu Phe Trp 20 <210> 550 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 550 Val Phe Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asp Asp Lys Tyr 1 5 10 15 Tyr Glu Phe Trp 20 <210> 551 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 551 Ala Tyr Ile Val Glu Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Glu Glu Phe Trp 20 <210> 552 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 552 His Trp Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Glu Asp Lys Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 553 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 553 His Tyr Asn Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asn Asp Glu Tyr 1 5 10 15 Phe Glu Phe Tyr 20 <210> 554 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 554 Trp Tyr Glu Val Glu Ile Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Gln Glu Phe Tyr 20 <210> 555 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 555 Tyr Val Thr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Lys Asp Glu Tyr 1 5 10 15 Phe Glu Phe Tyr 20 <210> 556 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 556 Asn Phe Thr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Lys Asp Glu Tyr 1 5 10 15 Tyr Glu Phe Tyr 20 <210> 557 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 557 Ser Tyr Glu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Gln 20 <210> 558 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (19)..(19) <223> C-terminal amidation <400> 558 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe <210> 559 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 559 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Asn 20 <210> 560 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 560 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Thr 20 <210> 561 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Covalently bound to fluorescent dye (Cy5-Dye) via maleimide coupled to thiol <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 561 Thr Gly Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr 1 5 10 15 Arg Glu Phe Thr Cys 20 <210> 562 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 562 Xaa Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr 1 5 10 15 Tyr Tyr Glu Phe Glu 20 <210> 563 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (4)..(4) <223> Xaa is tert-Leu (Tle) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 563 Glu Tyr Tyr Xaa Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 564 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Covalently bound to 400Mal-PEG <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 564 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu Cys 20 <210> 565 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 565 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu Cys 20 <210> 566 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> N-ethylmaleiimido Cys <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 566 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu Cys 20 <210> 567 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Maleiimide at each end of a 40kDa 4-brached PEG reacts with C-terminal Cysteine on each of four peptides identical to this sequence to form central tetravalent core <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 567 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu Cys 20 <210> 568 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Cys(Me-400MA) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 568 Glu Tyr Ile Val Thr Ala Gly Trp Tyr Asp Tyr Asn Lys Asp Ile Tyr 1 5 10 15 Tyr Glu Phe Lys Cys 20 <210> 569 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 569 Tyr Ala Glu Tyr Gly Tyr Ser Val Trp Asp Glu Glu Tyr Asn Tyr Thr 1 5 10 15 Tyr Thr Phe Asp 20 <210> 570 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 570 Tyr Trp Tyr Thr Asp Glu Asp Val Tyr Glu Phe Ser Tyr Asn Tyr Ala 1 5 10 15 Thr Tyr Glu Gly 20 <210> 571 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Epsilon-(Acetyl)-L-Lys <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 571 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu Lys 20 <210> 572 <211> 22 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is 6-aminohexanoic acid (Ahx) <220> <221> MISC_FEATURE <222> (22)..(22) <223> Epsilon-(Acetyl)-L-Lys <220> <221> MISC_FEATURE <222> (22)..(22) <223> C-terminal amidation <400> 572 Xaa Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr 1 5 10 15 Tyr Tyr Glu Phe Glu Lys 20 <210> 573 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Covalently bound to FeBABE <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 573 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu Cys 20 <210> 574 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Cys(FeBABE) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 574 Tyr Ala Glu Tyr Gly Tyr Ser Val Trp Asp Glu Glu Tyr Asn Tyr Thr 1 5 10 15 Tyr Thr Phe Asp Cys 20 <210> 575 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Covalently bound to Mal-Ttds <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 575 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu Lys 20 <210> 576 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 576 Ala Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 577 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 577 Glu Ala Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 578 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 578 Glu Tyr Ala Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 579 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 579 Glu Tyr Tyr Ala Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 580 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 580 Glu Tyr Tyr Val Ala Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 581 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 581 Glu Tyr Tyr Val Ser Ala Ala Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 582 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 582 Glu Tyr Tyr Val Ser Ala Gly Ala Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 583 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 583 Glu Tyr Tyr Val Ser Ala Gly Trp Ala Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 584 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 584 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Ala Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 585 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 585 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Ala Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 586 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 586 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Ala Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 587 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 587 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Ala Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 588 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 588 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Ala Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 589 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 589 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Ala 1 5 10 15 Tyr Glu Phe Glu 20 <210> 590 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 590 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Ala Glu Phe Glu 20 <210> 591 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 591 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Ala Phe Glu 20 <210> 592 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 592 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Ala Glu 20 <210> 593 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 593 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Ala 20 <210> 594 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 594 Cys Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 595 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 595 Glu Cys Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 596 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 596 Glu Tyr Cys Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 597 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 597 Glu Tyr Tyr Cys Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 598 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 598 Glu Tyr Tyr Val Cys Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 599 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 599 Glu Tyr Tyr Val Ser Cys Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 600 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 600 Glu Tyr Tyr Val Ser Ala Cys Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 601 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 601 Glu Tyr Tyr Val Ser Ala Gly Cys Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 602 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 602 Glu Tyr Tyr Val Ser Ala Gly Trp Cys Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 603 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 603 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Cys Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 604 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 604 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Cys Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 605 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 605 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Cys Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 606 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 606 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Cys Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 607 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 607 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Cys Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 608 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 608 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Cys Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 609 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 609 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Cys 1 5 10 15 Tyr Glu Phe Glu 20 <210> 610 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 610 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Cys Glu Phe Glu 20 <210> 611 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 611 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Cys Phe Glu 20 <210> 612 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 612 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Cys Glu 20 <210> 613 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 613 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Cys 20 <210> 614 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 614 Asp Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 615 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 615 Glu Asp Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 616 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 616 Glu Tyr Asp Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 617 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 617 Glu Tyr Tyr Asp Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 618 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 618 Glu Tyr Tyr Val Asp Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 619 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 619 Glu Tyr Tyr Val Ser Asp Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 620 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 620 Glu Tyr Tyr Val Ser Ala Asp Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 621 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 621 Glu Tyr Tyr Val Ser Ala Gly Asp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 622 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 622 Glu Tyr Tyr Val Ser Ala Gly Trp Asp Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 623 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 623 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Asp Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 624 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 624 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asp Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 625 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 625 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Asp Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 626 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 626 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Asp Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 627 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 627 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Asp 1 5 10 15 Tyr Glu Phe Glu 20 <210> 628 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 628 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Asp Glu Phe Glu 20 <210> 629 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 629 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Asp Phe Glu 20 <210> 630 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 630 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Asp Glu 20 <210> 631 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 631 Glu Glu Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 632 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 632 Glu Tyr Glu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 633 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 633 Glu Tyr Tyr Glu Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 634 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 634 Glu Tyr Tyr Val Glu Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 635 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 635 Glu Tyr Tyr Val Ser Glu Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 636 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 636 Glu Tyr Tyr Val Ser Ala Glu Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 637 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 637 Glu Tyr Tyr Val Ser Ala Gly Glu Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 638 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 638 Glu Tyr Tyr Val Ser Ala Gly Trp Glu Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 639 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 639 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Glu Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 640 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 640 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Glu Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 641 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 641 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Glu Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 642 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 642 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Glu Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 643 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 643 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Glu Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 644 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 644 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Glu Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 645 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 645 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Glu 1 5 10 15 Tyr Glu Phe Glu 20 <210> 646 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 646 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Glu Glu Phe Glu 20 <210> 647 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 647 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Glu Glu 20 <210> 648 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 648 Phe Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 649 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 649 Glu Phe Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 650 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 650 Glu Tyr Phe Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 651 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 651 Glu Tyr Tyr Phe Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 652 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 652 Glu Tyr Tyr Val Phe Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 653 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 653 Glu Tyr Tyr Val Ser Phe Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 654 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 654 Glu Tyr Tyr Val Ser Ala Phe Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 655 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 655 Glu Tyr Tyr Val Ser Ala Gly Phe Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 656 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 656 Glu Tyr Tyr Val Ser Ala Gly Trp Phe Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 657 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 657 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Phe Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 658 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 658 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Phe Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 659 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 659 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Phe Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 660 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 660 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Phe Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 661 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 661 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Phe Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 662 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 662 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Phe Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 663 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 663 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Phe 1 5 10 15 Tyr Glu Phe Glu 20 <210> 664 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 664 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Phe Glu Phe Glu 20 <210> 665 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 665 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Phe Phe Glu 20 <210> 666 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 666 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Phe 20 <210> 667 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 667 Gly Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 668 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 668 Glu Tyr Gly Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 669 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 669 Glu Tyr Tyr Gly Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 670 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 670 Glu Tyr Tyr Val Gly Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 671 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 671 Glu Tyr Tyr Val Ser Gly Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 672 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 672 Glu Tyr Tyr Val Ser Ala Gly Gly Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 673 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 673 Glu Tyr Tyr Val Ser Ala Gly Trp Gly Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 674 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 674 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Gly Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 675 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 675 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Gly Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 676 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 676 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Gly Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 677 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 677 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Gly Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 678 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 678 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Gly Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 679 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 679 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Gly Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 680 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 680 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Gly 1 5 10 15 Tyr Glu Phe Glu 20 <210> 681 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 681 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Gly Glu Phe Glu 20 <210> 682 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 682 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Gly Phe Glu 20 <210> 683 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 683 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Gly Glu 20 <210> 684 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 684 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Gly 20 <210> 685 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 685 His Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 686 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 686 Glu His Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 687 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 687 Glu Tyr His Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 688 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 688 Glu Tyr Tyr His Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 689 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 689 Glu Tyr Tyr Val His Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 690 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 690 Glu Tyr Tyr Val Ser His Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 691 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 691 Glu Tyr Tyr Val Ser Ala His Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 692 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 692 Glu Tyr Tyr Val Ser Ala Gly His Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 693 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 693 Glu Tyr Tyr Val Ser Ala Gly Trp His Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 694 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 694 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr His Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 695 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 695 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp His Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 696 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 696 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr His Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 697 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 697 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn His Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 698 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 698 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr His Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 699 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 699 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp His Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 700 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 700 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr His 1 5 10 15 Tyr Glu Phe Glu 20 <210> 701 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 701 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 His Glu Phe Glu 20 <210> 702 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 702 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr His Phe Glu 20 <210> 703 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 703 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu His Glu 20 <210> 704 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 704 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe His 20 <210> 705 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 705 Ile Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 706 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 706 Glu Ile Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 707 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 707 Glu Tyr Ile Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 708 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 708 Glu Tyr Tyr Ile Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 709 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 709 Glu Tyr Tyr Val Ile Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 710 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 710 Glu Tyr Tyr Val Ser Ile Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 711 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 711 Glu Tyr Tyr Val Ser Ala Ile Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 712 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 712 Glu Tyr Tyr Val Ser Ala Gly Ile Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 713 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 713 Glu Tyr Tyr Val Ser Ala Gly Trp Ile Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 714 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 714 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Ile Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 715 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 715 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Ile Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 716 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 716 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Ile Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 717 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 717 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Ile Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 718 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 718 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Ile Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 719 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 719 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Ile Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 720 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 720 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Ile 1 5 10 15 Tyr Glu Phe Glu 20 <210> 721 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 721 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Ile Glu Phe Glu 20 <210> 722 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 722 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Ile Phe Glu 20 <210> 723 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 723 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Ile Glu 20 <210> 724 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 724 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Ile 20 <210> 725 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 725 Lys Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 726 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 726 Glu Lys Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 727 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 727 Glu Tyr Lys Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 728 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 728 Glu Tyr Tyr Lys Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 729 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 729 Glu Tyr Tyr Val Lys Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 730 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 730 Glu Tyr Tyr Val Ser Lys Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 731 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 731 Glu Tyr Tyr Val Ser Ala Lys Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 732 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 732 Glu Tyr Tyr Val Ser Ala Gly Lys Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 733 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 733 Glu Tyr Tyr Val Ser Ala Gly Trp Lys Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 734 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 734 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Lys Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 735 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 735 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Lys Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 736 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 736 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Lys Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 737 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 737 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Lys Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 738 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 738 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Lys Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 739 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 739 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Lys Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 740 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 740 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Lys 1 5 10 15 Tyr Glu Phe Glu 20 <210> 741 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 741 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Lys Glu Phe Glu 20 <210> 742 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 742 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Lys Phe Glu 20 <210> 743 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 743 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Lys Glu 20 <210> 744 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 744 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Lys 20 <210> 745 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 745 Leu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 746 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 746 Glu Leu Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 747 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 747 Glu Tyr Leu Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 748 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 748 Glu Tyr Tyr Leu Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 749 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 749 Glu Tyr Tyr Val Leu Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 750 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 750 Glu Tyr Tyr Val Ser Leu Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 751 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 751 Glu Tyr Tyr Val Ser Ala Leu Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 752 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 752 Glu Tyr Tyr Val Ser Ala Gly Leu Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 753 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 753 Glu Tyr Tyr Val Ser Ala Gly Trp Leu Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 754 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 754 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Leu Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 755 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 755 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Leu Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 756 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 756 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Leu Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 757 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 757 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Leu Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 758 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 758 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Leu Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 759 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 759 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Leu Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 760 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 760 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Leu 1 5 10 15 Tyr Glu Phe Glu 20 <210> 761 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 761 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Leu Glu Phe Glu 20 <210> 762 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 762 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Leu Phe Glu 20 <210> 763 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 763 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Leu Glu 20 <210> 764 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 764 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Leu 20 <210> 765 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 765 Met Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 766 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 766 Glu Met Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 767 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 767 Glu Tyr Met Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 768 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 768 Glu Tyr Tyr Met Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 769 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 769 Glu Tyr Tyr Val Met Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 770 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 770 Glu Tyr Tyr Val Ser Met Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 771 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 771 Glu Tyr Tyr Val Ser Ala Met Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 772 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 772 Glu Tyr Tyr Val Ser Ala Gly Met Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 773 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 773 Glu Tyr Tyr Val Ser Ala Gly Trp Met Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 774 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 774 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Met Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 775 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 775 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Met Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 776 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 776 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Met Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 777 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 777 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Met Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 778 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 778 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Met Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 779 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 779 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Met Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 780 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 780 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Met 1 5 10 15 Tyr Glu Phe Glu 20 <210> 781 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 781 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Met Glu Phe Glu 20 <210> 782 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 782 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Met Phe Glu 20 <210> 783 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 783 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Met Glu 20 <210> 784 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 784 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Met 20 <210> 785 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 785 Asn Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 786 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 786 Glu Asn Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 787 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 787 Glu Tyr Asn Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 788 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 788 Glu Tyr Tyr Asn Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 789 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 789 Glu Tyr Tyr Val Asn Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 790 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 790 Glu Tyr Tyr Val Ser Asn Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 791 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 791 Glu Tyr Tyr Val Ser Ala Asn Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 792 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 792 Glu Tyr Tyr Val Ser Ala Gly Asn Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 793 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 793 Glu Tyr Tyr Val Ser Ala Gly Trp Asn Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 794 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 794 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asn Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 795 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 795 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Asn Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 796 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 796 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asn Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 797 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 797 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Asn Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 798 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 798 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Asn 1 5 10 15 Tyr Glu Phe Glu 20 <210> 799 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 799 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Asn Glu Phe Glu 20 <210> 800 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 800 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Asn Phe Glu 20 <210> 801 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 801 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Asn Glu 20 <210> 802 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 802 Pro Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 803 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 803 Glu Pro Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 804 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 804 Glu Tyr Pro Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 805 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 805 Glu Tyr Tyr Pro Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 806 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 806 Glu Tyr Tyr Val Pro Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 807 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 807 Glu Tyr Tyr Val Ser Pro Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 808 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 808 Glu Tyr Tyr Val Ser Ala Pro Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 809 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 809 Glu Tyr Tyr Val Ser Ala Gly Pro Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 810 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 810 Glu Tyr Tyr Val Ser Ala Gly Trp Pro Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 811 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 811 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Pro Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 812 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 812 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Pro Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 813 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 813 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Pro Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 814 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 814 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Pro Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 815 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 815 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Pro Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 816 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 816 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Pro Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 817 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 817 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Pro 1 5 10 15 Tyr Glu Phe Glu 20 <210> 818 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 818 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Pro Glu Phe Glu 20 <210> 819 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 819 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Pro Phe Glu 20 <210> 820 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 820 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Pro Glu 20 <210> 821 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 821 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Pro 20 <210> 822 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 822 Gln Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 823 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 823 Glu Gln Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 824 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 824 Glu Tyr Gln Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 825 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 825 Glu Tyr Tyr Gln Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 826 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 826 Glu Tyr Tyr Val Gln Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 827 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 827 Glu Tyr Tyr Val Ser Gln Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 828 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 828 Glu Tyr Tyr Val Ser Ala Gln Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 829 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 829 Glu Tyr Tyr Val Ser Ala Gly Gln Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 830 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 830 Glu Tyr Tyr Val Ser Ala Gly Trp Gln Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 831 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 831 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Gln Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 832 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 832 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Gln Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 833 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 833 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Gln Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 834 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 834 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Gln Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 835 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 835 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Gln Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 836 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 836 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Gln Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 837 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 837 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Gln 1 5 10 15 Tyr Glu Phe Glu 20 <210> 838 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 838 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Gln Glu Phe Glu 20 <210> 839 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 839 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Gln Phe Glu 20 <210> 840 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 840 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Gln Glu 20 <210> 841 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 841 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Gln 20 <210> 842 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 842 Arg Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 843 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 843 Glu Arg Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 844 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 844 Glu Tyr Arg Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 845 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 845 Glu Tyr Tyr Arg Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 846 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 846 Glu Tyr Tyr Val Arg Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 847 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 847 Glu Tyr Tyr Val Ser Arg Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 848 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 848 Glu Tyr Tyr Val Ser Ala Arg Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 849 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 849 Glu Tyr Tyr Val Ser Ala Gly Arg Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 850 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 850 Glu Tyr Tyr Val Ser Ala Gly Trp Arg Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 851 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 851 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Arg Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 852 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 852 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Arg Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 853 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 853 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Arg Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 854 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 854 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Arg Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 855 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 855 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Arg Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 856 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 856 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Arg Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 857 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 857 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Arg 1 5 10 15 Tyr Glu Phe Glu 20 <210> 858 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 858 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Arg Glu Phe Glu 20 <210> 859 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 859 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Arg Phe Glu 20 <210> 860 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 860 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Arg Glu 20 <210> 861 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 861 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Arg 20 <210> 862 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 862 Ser Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 863 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 863 Glu Ser Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 864 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 864 Glu Tyr Ser Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 865 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 865 Glu Tyr Tyr Ser Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 866 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 866 Glu Tyr Tyr Val Ser Ser Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 867 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 867 Glu Tyr Tyr Val Ser Ala Ser Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 868 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 868 Glu Tyr Tyr Val Ser Ala Gly Ser Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 869 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 869 Glu Tyr Tyr Val Ser Ala Gly Trp Ser Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 870 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 870 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Ser Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 871 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 871 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Ser Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 872 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 872 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Ser Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 873 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 873 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Ser Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 874 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 874 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Ser Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 875 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 875 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Ser Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 876 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 876 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Ser 1 5 10 15 Tyr Glu Phe Glu 20 <210> 877 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 877 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Ser Glu Phe Glu 20 <210> 878 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 878 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Ser Phe Glu 20 <210> 879 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 879 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Ser Glu 20 <210> 880 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 880 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Ser 20 <210> 881 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 881 Thr Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 882 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 882 Glu Thr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 883 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 883 Glu Tyr Thr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 884 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 884 Glu Tyr Tyr Thr Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 885 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 885 Glu Tyr Tyr Val Ser Thr Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 886 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 886 Glu Tyr Tyr Val Ser Ala Thr Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 887 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 887 Glu Tyr Tyr Val Ser Ala Gly Thr Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 888 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 888 Glu Tyr Tyr Val Ser Ala Gly Trp Thr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 889 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 889 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Thr Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 890 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 890 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Thr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 891 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 891 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Thr Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 892 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 892 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Thr Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 893 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 893 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Thr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 894 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 894 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Thr Glu Phe Glu 20 <210> 895 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 895 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Thr Phe Glu 20 <210> 896 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 896 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Thr Glu 20 <210> 897 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 897 Val Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 898 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 898 Glu Val Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 899 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 899 Glu Tyr Val Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 900 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 900 Glu Tyr Tyr Val Val Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 901 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 901 Glu Tyr Tyr Val Ser Val Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 902 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 902 Glu Tyr Tyr Val Ser Ala Val Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 903 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 903 Glu Tyr Tyr Val Ser Ala Gly Val Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 904 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 904 Glu Tyr Tyr Val Ser Ala Gly Trp Val Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 905 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 905 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Val Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 906 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 906 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Val Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 907 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 907 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Val Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 908 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 908 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Val Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 909 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 909 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Val Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 910 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 910 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Val Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 911 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 911 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Val 1 5 10 15 Tyr Glu Phe Glu 20 <210> 912 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 912 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Val Glu Phe Glu 20 <210> 913 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 913 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Val Phe Glu 20 <210> 914 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 914 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Val Glu 20 <210> 915 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 915 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Val 20 <210> 916 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 916 Trp Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 917 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 917 Glu Trp Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 918 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 918 Glu Tyr Trp Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 919 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 919 Glu Tyr Tyr Trp Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 920 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 920 Glu Tyr Tyr Val Trp Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 921 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 921 Glu Tyr Tyr Val Ser Trp Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 922 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 922 Glu Tyr Tyr Val Ser Ala Trp Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 923 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 923 Glu Tyr Tyr Val Ser Ala Gly Trp Trp Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 924 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 924 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Trp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 925 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 925 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Trp Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 926 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 926 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Trp Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 927 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 927 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Trp Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 928 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 928 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Trp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 929 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 929 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Trp Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 930 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 930 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Trp 1 5 10 15 Tyr Glu Phe Glu 20 <210> 931 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 931 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Trp Glu Phe Glu 20 <210> 932 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 932 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Trp Phe Glu 20 <210> 933 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 933 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Trp Glu 20 <210> 934 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 934 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Trp 20 <210> 935 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 935 Tyr Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 936 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 936 Glu Tyr Tyr Tyr Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 937 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 937 Glu Tyr Tyr Val Tyr Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 938 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 938 Glu Tyr Tyr Val Ser Tyr Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 939 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 939 Glu Tyr Tyr Val Ser Ala Tyr Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 940 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 940 Glu Tyr Tyr Val Ser Ala Gly Tyr Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 941 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 941 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Tyr Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 942 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 942 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Tyr Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 943 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 943 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Tyr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 944 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 944 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Tyr Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 945 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 945 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Tyr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 946 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 946 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Tyr Phe Glu 20 <210> 947 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 947 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Tyr Glu 20 <210> 948 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 948 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Tyr 20 <210> 949 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (1)..(1) <223> D-Glu <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 949 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 950 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (2)..(2) <223> D-Tyr <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 950 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 951 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (3)..(3) <223> D-Tyr <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 951 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 952 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (4)..(4) <223> D-Val <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 952 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 953 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (5)..(5) <223> D-Ser <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 953 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 954 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (6)..(6) <223> D-Ala <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 954 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 955 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (7)..(7) <223> D-Ala <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 955 Glu Tyr Tyr Val Ser Ala Ala Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 956 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> D-Trp <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 956 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 957 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (9)..(9) <223> D-Tyr <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 957 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 958 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (10)..(10) <223> D-Asp <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 958 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 959 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> D-Tyr <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 959 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 960 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (12)..(12) <223> D-Asn <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 960 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 961 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 961 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 962 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> D-Asp <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 962 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 963 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (15)..(15) <223> D-Thr <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 963 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 964 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (16)..(16) <223> D-Tyr <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 964 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 965 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> D-Tyr <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 965 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 966 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> D-Glu <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 966 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 967 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (18)..(18) <223> D-Phe <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 967 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 968 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> D-Glu <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 968 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 969 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (1)..(1) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 969 Pro Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 970 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (2)..(2) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 970 Glu Pro Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 971 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (3)..(3) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 971 Glu Tyr Pro Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 972 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (4)..(4) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 972 Glu Tyr Tyr Pro Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 973 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (5)..(5) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 973 Glu Tyr Tyr Val Pro Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 974 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (6)..(6) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 974 Glu Tyr Tyr Val Ser Pro Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 975 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (7)..(7) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 975 Glu Tyr Tyr Val Ser Ala Pro Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 976 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 976 Glu Tyr Tyr Val Ser Ala Gly Pro Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 977 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (9)..(9) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 977 Glu Tyr Tyr Val Ser Ala Gly Trp Pro Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 978 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (10)..(10) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 978 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Pro Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 979 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 979 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Pro Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 980 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (12)..(12) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 980 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Pro Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 981 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (13)..(13) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 981 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Pro Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 982 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 982 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Pro Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 983 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (15)..(15) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 983 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Pro Tyr 1 5 10 15 Tyr Glu Phe Glu 20 <210> 984 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (16)..(16) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 984 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Pro 1 5 10 15 Tyr Glu Phe Glu 20 <210> 985 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 985 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Pro Glu Phe Glu 20 <210> 986 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (18)..(18) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 986 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Pro Phe Glu 20 <210> 987 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (19)..(19) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 987 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Pro Glu 20 <210> 988 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> D-Pro <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 988 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Pro 20 <210> 989 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (19)..(19) <223> C-terminal amidation <400> 989 Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr Tyr 1 5 10 15 Glu Phe Glu <210> 990 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (18)..(18) <223> C-terminal amidation <400> 990 Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr Tyr Glu 1 5 10 15 Phe Glu <210> 991 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 991 Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr Tyr Glu Phe 1 5 10 15 Glu <210> 992 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (16)..(16) <223> C-terminal amidation <400> 992 Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr Tyr Glu Phe Glu 1 5 10 15 <210> 993 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (18)..(18) <223> C-terminal amidation <400> 993 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu <210> 994 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 994 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr <210> 995 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 995 Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr Tyr Glu 1 5 10 15 Phe <210> 996 <211> 15 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (15)..(15) <223> C-terminal amidation <400> 996 Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr Tyr Glu 1 5 10 15 <210> 997 <211> 13 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (13)..(13) <223> C-terminal amidation <400> 997 Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr Tyr 1 5 10 <210> 998 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 998 Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 <210> 999 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Side chain amino group of Lys covalently bound to human serum albumin (HSA) via reaction of Cysteine-sidechain in HSA with Mal-Ttds <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 999 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu Lys 20 <210> 1000 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminus modified with 20kDa methoxy PEG via amino hexanoic acid (Ahx) <220> <221> MISC_FEATURE <222> (21)..(21) <223> Covalently bound to 20kDa methoxy PEG <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1000 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu Lys 20 <210> 1001 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminus modified with 20kDa methoxy PEG bound to amino hexanoic acid (Ahx) via glutaric acid linker <220> <221> MISC_FEATURE <222> (21)..(21) <223> Covalently bound to 20kDa methoxy PEG via glutaric acid linker <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1001 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu Lys 20 <210> 1002 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminus modified with branched 20kDa PEG bound to amino hexanoix acid via glutaric acid linker <220> <221> MISC_FEATURE <222> (22)..(22) <223> Covalently bound to branched 20kDa PEG via glutaric acid linker <220> <221> MISC_FEATURE <222> (22)..(22) <223> C-terminal amidation <400> 1002 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu Lys 20 <210> 1003 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Epsilon amine bound to Ttds which is bound to octadecanedioyl via gamma-Glu <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1003 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu Lys 20 <210> 1004 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminus modified with glutaric acid via amino hexanoic acid <220> <221> MISC_FEATURE <222> (22)..(22) <223> Covalently bound to glutaric acid <220> <221> MISC_FEATURE <222> (22)..(22) <223> C-terminal amidation <400> 1004 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu Lys 20 <210> 1005 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> Side chain amino group of Lys covalently bound to mouse serum albumin (MSA) via reaction of Cysteine-sidechain in MSA with Mal-Ttds <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1005 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu Lys 20 <210> 1006 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (8)..(21) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1006 Xaa Val Leu Ser Trp Ser Val Cys Tyr Leu Gln Gln Glu Ala Tyr Arg 1 5 10 15 Ser Thr Thr Ile Cys 20 <210> 1007 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (10)..(20) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1007 Xaa Arg Gly Leu Glu Glu Gln Glu Thr Cys Val Arg Val Ser Ser Arg 1 5 10 15 Val Glu Ile Cys Trp 20 <210> 1008 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (4)..(14) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1008 Xaa Asn Trp Cys Ile Ala Ile Ser Pro Thr Met Asp Leu Cys Leu Tyr 1 5 10 15 Leu Arg Lys Glu Asn 20 <210> 1009 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (6)..(16) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1009 Xaa Leu Asp Asp Met Cys Tyr Ala Leu Thr Glu His Val Ser Ile Cys 1 5 10 15 Tyr Gly Ala Ala Ser 20 <210> 1010 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (6)..(16) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1010 Xaa Arg Arg Glu Met Cys His Ala Leu Gly Gly Met Val Thr Val Cys 1 5 10 15 Val Gly Trp Glu Trp 20 <210> 1011 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (8)..(18) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1011 Xaa Val Phe Gln Lys Glu Glu Cys Val Leu Ala Thr Glu Ser Val Trp 1 5 10 15 Val Cys Trp Gly Asn 20 <210> 1012 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (5)..(15) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1012 Xaa Trp Glu Val Cys Val Pro Leu Ser Ala Gly Gly Met Ile Cys Val 1 5 10 15 Gly Arg Thr Asp Arg 20 <210> 1013 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (5)..(12) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1013 Xaa Val Trp Leu Cys Leu Glu Glu Thr Gly Leu Cys Val Gln Val Leu 1 5 10 15 Gly Ala Ala Arg Phe 20 <210> 1014 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1014 Xaa Ala Asn Lys Met Leu Gly Ser Ser Gly Pro Trp Tyr Trp Ile Glu 1 5 10 15 Val Gly Trp Ser Ser 20 <210> 1015 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1015 Xaa Gly Gly Ser Leu Ser Ile His Ile Asp Trp Gly Trp Ala Pro Ser 1 5 10 15 Ser Arg Trp Thr His 20 <210> 1016 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1016 Xaa Trp Arg His Gly Ala Ile Gln Trp Gly Trp Ser Glu Ser Ser Arg 1 5 10 15 Tyr Arg His Ser Leu 20 <210> 1017 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1017 Xaa Trp Phe Gly Trp Thr Trp Gly Leu Thr Arg Ser Ser Glu Tyr Gln 1 5 10 15 His Ser Gly Asn Lys 20 <210> 1018 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1018 Xaa Gly Arg Asn Val Lys Arg Ser Tyr Trp Gly Val Val Asp Trp Gly 1 5 10 15 Trp Glu Glu Ser Ser 20 <210> 1019 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1019 Xaa Gly Leu Gly Trp Glu Val Gly Trp His Val Leu Glu Ser Ser His 1 5 10 15 Asp Leu Thr Ile His 20 <210> 1020 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1020 Xaa Tyr Tyr Val Ala Val Gly Trp Tyr Arg Ile Thr Thr Gly Glu Ser 1 5 10 15 Met Trp Met Met Val 20 <210> 1021 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1021 Xaa Tyr Ser Val Gln Val Gly Trp Tyr Met Asp Ala Ser His Tyr Gln 1 5 10 15 His Ala Met Arg His 20 <210> 1022 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1022 Xaa Val Ile Arg Val Gly Trp Tyr Asn Arg Val Ser Gly Gln Ile Met 1 5 10 15 Trp Val Gly Leu Ile 20 <210> 1023 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1023 Xaa Trp Val Leu Gly Trp Tyr Asp Lys Ala Leu Glu Thr Glu Tyr Asp 1 5 10 15 Tyr Met Tyr Gly Gly 20 <210> 1024 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1024 Xaa Val Glu Val Gly Trp Tyr Leu Val Asp Arg Asp Val Trp Met Leu 1 5 10 15 Trp Ser Asp His Glu 20 <210> 1025 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1025 Xaa Gly Trp Phe Met Glu Val Ala Thr Val Leu Gly Val Ile Glu Val 1 5 10 15 Gly Trp Val Val 20 <210> 1026 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1026 Xaa Met Trp Ile Gly Trp His Thr Val Ser Glu Glu Ser Asp His Trp 1 5 10 15 Phe Ala Trp Val Thr 20 <210> 1027 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1027 Xaa Trp Glu Asn Glu Thr Leu Leu Arg Leu Pro Ser Gly Ala Met Val 1 5 10 15 Trp Val Gly Phe Thr 20 <210> 1028 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1028 Xaa Arg Leu Gly Ile Gln Leu Trp Gly Ala Thr Leu Ser Gln Glu Trp 1 5 10 15 Leu Val Trp Glu Leu 20 <210> 1029 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1029 Xaa Asn Tyr Val Arg Thr Glu Val Leu Trp Glu Asn Glu Val Val Gly 1 5 10 15 Val Trp Leu Glu Trp 20 <210> 1030 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1030 Xaa Gly Leu Ser Trp His Leu Tyr Leu Gly Asn Gly Gly Thr Val Thr 1 5 10 15 Ile Gly Tyr Glu Thr 20 <210> 1031 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1031 Xaa Ser Leu Gly His Val His Met Gly Arg Arg Tyr Thr Val Glu Leu 1 5 10 15 Arg Trp Glu Arg Ala 20 <210> 1032 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1032 Xaa Glu Leu Pro Leu Ala Leu Gln Gly Met Glu Ser His Gly Ile Val 1 5 10 15 Ser Trp Gly Trp Ala 20 <210> 1033 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1033 Xaa Phe Gly Ser Glu Trp Gln Ile Trp Ile Leu Leu Asp Ser Gly Asp 1 5 10 15 Glu Tyr Met Leu Gly 20 <210> 1034 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1034 Xaa Ile Phe Gly Val Ile Glu Thr Phe Ala Gly Thr Val Ser Phe Gly 1 5 10 15 Trp Glu Trp Tyr Asp 20 <210> 1035 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1035 Xaa Lys Asp Asn Glu Glu Leu Val Leu Met Arg Gly Arg Leu Glu Ile 1 5 10 15 Trp Leu Gly Met Glu 20 <210> 1036 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1036 Xaa Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu 1 5 10 15 Ile Gly Trp Glu Ile 20 <210> 1037 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1037 Xaa Tyr Ile Leu Trp Ser Val Tyr Val Gly Pro Gly Ile Glu Val Gly 1 5 10 15 Trp Thr Glu Ser Ala 20 <210> 1038 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1038 Xaa Trp Lys Val Trp Arg Leu Gly Gly Val Glu Leu Trp Tyr Lys Glu 1 5 10 15 Phe Gly Ser Glu Arg 20 <210> 1039 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1039 Xaa Arg Glu Arg Glu Phe Arg Ile Asn Phe Tyr Val Ser Trp Gly Trp 1 5 10 15 Glu Pro Ser Gly Ile 20 <210> 1040 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1040 Xaa Leu Arg Lys Arg Leu Thr Asn Leu Asp Ser Ile Phe Val Val Glu 1 5 10 15 Leu Trp Trp Glu Tyr 20 <210> 1041 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1041 Xaa Trp Trp Val Thr Asn Asn Val Met Val Gly Trp Glu Phe Val Gln 1 5 10 15 Pro Gly Glu Pro Thr 20 <210> 1042 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1042 Xaa His Glu Gln Thr Val Thr Leu Trp Tyr His His Arg Glu Thr Gly 1 5 10 15 Val Asp Tyr Arg Ser 20 <210> 1043 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1043 Xaa Gly Arg Trp Lys Ser Gly Glu Ser Thr Trp Thr Val Glu Leu Phe 1 5 10 15 Trp Val Trp Asn Gly 20 <210> 1044 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1044 Xaa Val Glu Trp Glu Leu Trp Val Glu Trp Val Val Glu Gly Gln Glu 1 5 10 15 Val Arg Val Lys Leu 20 <210> 1045 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1045 Xaa Trp Met Val Lys Phe Ser Val Val Arg Gly Ile Thr Glu Val Gly 1 5 10 15 Trp Glu Val Leu Asp 20 <210> 1046 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1046 Xaa Gly Phe Ala Ile Trp Ile Gly Leu Ile Lys Gly His His Ser Tyr 1 5 10 15 Glu Trp Glu Leu Arg 20 <210> 1047 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1047 Xaa Glu Ser Thr Ile Glu Phe Trp Ile Glu Gly Lys Leu Val Pro Glu 1 5 10 15 Phe Ile Phe Thr Tyr 20 <210> 1048 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1048 Xaa His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val 1 5 10 15 Gly Trp Glu Phe Val 20 <210> 1049 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (8)..(19) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1049 Xaa Gly Ser Thr Val Gln Val Cys Trp Tyr Trp Glu Glu Val Glu Val 1 5 10 15 Glu Thr Cys Val Ser 20 <210> 1050 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (9)..(18) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1050 Xaa Gly Asn Ala Lys Val Trp Leu Cys Val Glu Asp Lys His Met Thr 1 5 10 15 Val Cys Thr Leu Ile 20 <210> 1051 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1051 Xaa Asp Leu Asp Pro Arg Ile Val Leu Val Gly Asn Gly Glu Ile Glu 1 5 10 15 Ile Gly Trp Ser Ile 20 <210> 1052 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1052 Xaa Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile 1 5 10 15 Glu Tyr Gly Trp Glu 20 <210> 1053 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1053 Xaa Asn Gln Gly Tyr Thr His Asn Thr Lys Leu Arg Phe Tyr Val Glu 1 5 10 15 Leu Gly Trp Glu His 20 <210> 1054 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1054 Xaa Trp Ile Glu Val Gly Trp Phe Glu Ala Asn Thr Gly Arg His Arg 1 5 10 15 Thr Trp Thr Ile Val 20 <210> 1055 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1055 Xaa Ile Trp Val Gly Trp Glu Asp Val Arg Arg Gly Arg Ile Leu Glu 1 5 10 15 Glu Ile Thr Trp Lys 20 <210> 1056 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1056 Xaa Lys Tyr Leu Leu Leu Asp Phe Thr Phe Trp Leu Thr Lys Glu Val 1 5 10 15 Gly Val Gly Trp 20 <210> 1057 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1057 Xaa Val Trp Val Gly Trp Thr Glu Arg Arg Gly Ser Lys Glu Gln Val 1 5 10 15 Leu Trp Glu Val Lys 20 <210> 1058 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1058 Xaa Glu Val Arg Tyr Arg Phe Glu Gly Ile Pro Phe Phe His Val Ile 1 5 10 15 Phe Gly Trp Glu Phe 20 <210> 1059 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1059 Xaa Tyr Ser Val Leu Val Trp Arg Ala Gly Gly Gly Gln Val Glu Leu 1 5 10 15 Trp Met Ser Arg Val 20 <210> 1060 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1060 Xaa Pro Ile Trp Glu Arg Asp Ser Val Pro Arg Trp Met Tyr Ser Ile 1 5 10 15 Glu Leu Tyr Trp Glu 20 <210> 1061 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1061 Xaa Trp Arg Trp Ser Ile Val Val Gly Tyr Gln Trp Lys Gly Thr Asp 1 5 10 15 His Asp Leu Trp Ala 20 <210> 1062 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1062 Xaa Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile 1 5 10 15 Trp Arg Tyr Pro Ser 20 <210> 1063 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1063 Xaa Trp Phe Gln Arg Glu Tyr Glu Ile Lys Lys Gly Gln Ile Trp Leu 1 5 10 15 Val Ile Arg Val Gly 20 <210> 1064 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1064 Xaa Gln Val Trp Val Gly Tyr Tyr Asn Thr Ile Glu Asp Thr Glu Leu 1 5 10 15 Val Met Trp Thr Val 20 <210> 1065 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1065 Xaa Arg Ile Trp Ile Gly Met Tyr Leu Gly Gly Thr Leu Thr Trp Glu 1 5 10 15 Trp Glu Val Ile Pro 20 <210> 1066 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1066 Xaa Tyr Ser Glu Ile Thr Ile Gly Val Tyr Trp Glu Gln Tyr Ser Tyr 1 5 10 15 Asp Phe Tyr Asn Phe 20 <210> 1067 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1067 Xaa Val Val Arg His Trp His Tyr Val Gly Met Glu Phe Gly Phe Glu 1 5 10 15 Lys Val Arg Glu Val 20 <210> 1068 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (5)..(15) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1068 Xaa Gly Glu Ser Cys Val Arg Ile Asn His Lys Val Trp Val Cys Trp 1 5 10 15 Asp Met Gly Ser Glu 20 <210> 1069 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (10)..(20) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1069 Xaa Tyr Glu Arg Gly Thr Phe His Thr Cys Ser Arg Tyr Asp Glu Arg 1 5 10 15 Ile Asp Val Cys Trp 20 <210> 1070 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (6)..(20) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1070 Xaa Gly Val Ile Val Cys Tyr Thr His Thr Ser Ser Trp His Gly His 1 5 10 15 Asn Asp Trp Cys Tyr 20 <210> 1071 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (16)..(19) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1071 Xaa Ser His Arg Lys Ser Gln Leu His Gln Gln Tyr Arg Ser Arg Cys 1 5 10 15 Glu Arg Cys Ser Asn 20 <210> 1072 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1072 Xaa Leu Val Arg Val Arg Leu Thr Gln Phe Ala Gln Tyr Ser Arg Arg 1 5 10 15 Ser Gly Val Ala Phe 20 <210> 1073 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1073 Xaa Ser Ser Trp Asn Gly Gln Arg Ala Trp Met Leu Val Gly Met Arg 1 5 10 15 Gly Val Ala Val Asn 20 <210> 1074 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1074 Xaa Gly Val Pro Gly Leu Lys Ser Arg Tyr Ser Glu Gly Leu Ser Leu 1 5 10 15 Asp Thr Ser Trp Leu 20 <210> 1075 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1075 Xaa Ser Val Glu Ala Ser Asp Leu Asn Phe Tyr Phe Val Met Ser Ala 1 5 10 15 Trp Ser Lys Ile Ile 20 <210> 1076 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1076 Xaa Thr Leu Glu Gly Arg Arg Val Ile Leu Val Arg Met Val Trp Arg 1 5 10 15 Trp Thr Tyr His Val 20 <210> 1077 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1077 Xaa Lys Trp Phe Thr Ile Thr Arg Phe Ala Thr Leu His Thr Ser Tyr 1 5 10 15 Ile Phe Ile Gln Asn 20 <210> 1078 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1078 Xaa Asn Arg Ile His Leu Ser Trp Gly Thr Lys Asn Gln Gly Phe Thr 1 5 10 15 Lys Leu Lys Arg Ile 20 <210> 1079 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1079 Xaa Gln Ala Ile Lys Gly Arg Ile His Gly Asp Ile Glu Ser Asp Arg 1 5 10 15 Tyr Ser Val Tyr Tyr 20 <210> 1080 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1080 Xaa Ala Gly Ile Gln Leu Val Leu Glu Trp Tyr Gly His Arg Val Ile 1 5 10 15 Val Ile Gln Leu Gly 20 <210> 1081 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1081 Xaa Val Tyr Ala Asp Ile Asn Met Leu Ala Ser Ile Thr Trp Phe Ala 1 5 10 15 Arg Pro Tyr Met Asp 20 <210> 1082 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1082 Xaa Phe Ile Trp Ile Val Leu Met Pro Arg Arg Gly Thr Pro Lys Arg 1 5 10 15 Glu Trp Ala Tyr Tyr 20 <210> 1083 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1083 Xaa Trp Ser Arg Leu Leu Ala Arg Val Val Trp Lys Ser Gly Thr Ile 1 5 10 15 Glu Val Gly Trp Ala 20 <210> 1084 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1084 Xaa Gly Tyr Trp Thr Val Glu Phe Trp Val Gln Trp Ser Gly Gly Asp 1 5 10 15 Asp Val Leu Ile Arg 20 <210> 1085 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1085 Xaa Glu Asp Val Gly Lys Phe Lys Trp Tyr Ile Glu Val Trp Trp Gln 1 5 10 15 Asn Met Asp Glu Ala 20 <210> 1086 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1086 Xaa Glu Asp Trp Gly Ile Arg Trp Gly Trp Arg Tyr Thr Leu Arg Trp 1 5 10 15 Glu Ala Val Leu Trp 20 <210> 1087 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1087 Xaa Phe Ala Thr Leu His Glu Trp Arg Ser Gly Phe Met Arg His Arg 1 5 10 15 His Leu Arg Ala Ser 20 <210> 1088 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1088 Xaa His Gly Asp Ser Met Trp Lys Trp Thr Val Met Arg Ala Pro Ala 1 5 10 15 Thr Gly Arg Gly Met 20 <210> 1089 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1089 Xaa Gly His Gly Met Asn Arg Trp His Arg Arg Leu Glu Ala Ile Met 1 5 10 15 Asp Ile Lys Arg Leu 20 <210> 1090 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1090 Xaa Arg Arg Tyr Glu Arg Ala Thr Ala Ser Ser Arg Arg Glu Ser Gln 1 5 10 15 Leu Val Asp Ser Ile 20 <210> 1091 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1091 Xaa Gly Gly His Cys Thr His Thr Pro Trp Thr Tyr Gly Val Leu Ala 1 5 10 15 Trp Val Ser Arg Thr 20 <210> 1092 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1092 Xaa Phe Trp Ser Trp Gly Tyr Gln Ser Leu Asp Gly Glu Trp Thr Ser 1 5 10 15 Glu Trp Ala Arg Ile 20 <210> 1093 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1093 Xaa Thr Arg Ser Gly Glu Arg Gly Arg Lys Arg Val Leu Ser Ser Tyr 1 5 10 15 Trp Leu His Ser Trp 20 <210> 1094 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1094 Xaa Trp His Trp Trp Met Gly Thr Tyr Gln Ser Ser Pro Trp Ser Thr 1 5 10 15 Glu Thr Glu Trp Trp 20 <210> 1095 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1095 Xaa Ser Ser Gly His Pro Arg Val Arg Ser Lys Tyr Ser Trp Gly Leu 1 5 10 15 Ile Pro Leu Arg Arg 20 <210> 1096 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1096 Xaa Thr Gly Ile Tyr Ala Trp Gly Trp Glu Ile Arg Ser Glu Trp Gln 1 5 10 15 Asn Asp Ser Trp Phe 20 <210> 1097 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1097 Xaa Gly Trp Asn Val Phe Tyr Ile Phe Arg Val Phe Glu Gly Lys Pro 1 5 10 15 Lys Ala Trp Val Met 20 <210> 1098 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1098 Xaa Gly Gly Thr Leu Trp Gln Phe Glu His Gly Glu His Tyr Leu Ile 1 5 10 15 Met Leu Gly Trp Glu 20 <210> 1099 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1099 Xaa Leu Glu Gly Asn His Trp Arg Asp Arg Tyr His His Ser Val Lys 1 5 10 15 Ala Ser Val Pro Met 20 <210> 1100 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1100 Xaa Ile Trp Gly Ala Gln Arg Trp Arg Asp His Arg Lys Gly Leu Val 1 5 10 15 Ser Met Ser Met Ser 20 <210> 1101 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1101 Xaa Arg Gly Val Arg Arg Met Pro Lys Ser Tyr Pro Arg Gln His Thr 1 5 10 15 Ala Ile Arg Val Leu 20 <210> 1102 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1102 Xaa Leu Met Ala Val His Val Pro Ser Thr Asn Asn Thr Lys Trp Val 1 5 10 15 Ile Asp Ile Cys Lys 20 <210> 1103 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1103 Xaa Gly Ile Trp Ile Gly Gln Ser Lys Tyr Ile Trp Arg Ser Gln Arg 1 5 10 15 Gly Glu Gln Thr Ile 20 <210> 1104 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1104 Xaa Tyr Glu Gly Ile Lys Pro Trp Thr Gly Ser Arg Val Met Met Leu 1 5 10 15 Met Asp Met Leu Thr 20 <210> 1105 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (5)..(15) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (18)..(18) <223> C-terminal amidation <400> 1105 Xaa Lys Glu Ser Cys Phe Trp Val Ser Lys Trp Val Ala Val Cys Gly 1 5 10 15 His Tyr <210> 1106 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (9)..(19) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1106 Xaa Val Ile Ser Gln Gly His His Cys Trp His Val Asn Glu Lys Ile 1 5 10 15 Ala Val Cys Trp Leu 20 <210> 1107 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (9)..(19) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1107 Xaa Glu Arg Glu Asp Thr Thr Tyr Cys Val Val Val Ala Ser Gly Val 1 5 10 15 Glu Leu Cys Trp Gln 20 <210> 1108 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (4)..(14) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1108 Xaa Glu His Cys Arg Gln Ile Ala Pro Asp Val Met Leu Cys Trp Glu 1 5 10 15 Trp Arg Ala Lys Ser 20 <210> 1109 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (8)..(18) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1109 Xaa Ser Ala Gly Ser Val Ser Cys Phe Trp Val Ser Ser Gln Val Ser 1 5 10 15 Val Cys Trp Gln Leu 20 <210> 1110 <211> 7 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (7)..(7) <223> C-terminal amidation <400> 1110 Xaa Gln Leu Glu Leu Gly Phe 1 5 <210> 1111 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1111 Xaa Arg Gly Trp Thr Arg Tyr Trp Ile Glu Val Gly Trp Trp His Ile 1 5 10 15 Asp Glu Glu Leu Thr 20 <210> 1112 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1112 Xaa Phe Val His Val Gly Trp Val Glu Tyr Gly Trp Val Leu Arg Ser 1 5 10 15 Asp Tyr Arg His Ser 20 <210> 1113 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1113 Xaa His Ser Glu Val Ser Trp Leu Arg Ser Asn Asp Tyr Tyr Ile Glu 1 5 10 15 Phe Gly Trp Glu Trp 20 <210> 1114 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1114 Xaa Arg Asp Ile Trp Asp Leu Trp Thr Tyr Arg Ile Glu Phe Gly Trp 1 5 10 15 Glu Trp Ser Asp Asp 20 <210> 1115 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1115 Xaa Tyr Gln His Gly Glu Asp Gly Trp Tyr Trp Ile Glu Phe Gly Trp 1 5 10 15 Glu Phe Val Asp Leu 20 <210> 1116 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1116 Xaa Ala Glu Lys Val Asp Lys Glu Ser His Val Ser Tyr Thr Val Glu 1 5 10 15 Leu Trp Trp Glu Tyr 20 <210> 1117 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1117 Xaa Arg Trp Gln Arg Leu Gly Lys Gly Glu Thr Trp Glu Phe Trp Ala 1 5 10 15 Tyr Ile Pro Val Val 20 <210> 1118 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1118 Xaa Trp Thr Ile Gly Leu Trp Trp Glu Asn Glu His Glu Glu Val Met 1 5 10 15 Ile Trp Gln Val Gln 20 <210> 1119 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1119 Xaa Trp Ile Lys Ile Gly Trp His His Arg Asp His Glu Trp Asp Glu 1 5 10 15 Asp Ile Gly Phe Met 20 <210> 1120 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1120 Xaa Trp Glu Leu Trp Ser Met Asp Ser Leu Gly Lys His Thr Ile Leu 1 5 10 15 Gly Phe Gly Lys Trp 20 <210> 1121 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1121 Xaa Phe Arg Ile Glu Leu Trp Tyr Arg Glu Gly Lys Ser Gly Asn Glu 1 5 10 15 Lys Leu Val Trp Ser 20 <210> 1122 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1122 Xaa Ser Leu Gly His Val His Met Gly Arg Arg Tyr Thr Val Glu Leu 1 5 10 15 Arg Trp Glu Arg Ala 20 <210> 1123 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1123 Xaa Ser Val Glu Phe Gly Phe Tyr Asp Val Glu Asn Ser Met Asp Trp 1 5 10 15 Thr Val Gly Trp Val 20 <210> 1124 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (4)..(14) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1124 Xaa Asp Lys Cys Met Gln Ala Ser Gln Val Val Trp Val Cys Val His 1 5 10 15 Gln Glu Trp Asp Pro 20 <210> 1125 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1125 Xaa Asp Leu Asp Pro Arg Ile Val Leu Val Gly Asn Gly Glu Ile Glu 1 5 10 15 Ile Gly Trp Ser Ile 20 <210> 1126 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (6)..(16) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1126 Xaa Glu Ala Trp Asn Cys Ile Val Val Ser Lys Asn Ile Ser Val Cys 1 5 10 15 Trp Ser Lys Ser Tyr 20 <210> 1127 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (6)..(16) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1127 Xaa Glu Gly Glu Gln Cys Val Val Leu Arg Ser Gly Gly Ser Val Cys 1 5 10 15 Val Gly Phe Glu Arg 20 <210> 1128 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1128 Xaa Glu Leu Pro Leu Ala Leu Gln Gly Met Glu Ser His Gly Ile Val 1 5 10 15 Ser Trp Gly Trp Ala 20 <210> 1129 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (4)..(15) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1129 Xaa Glu Tyr Cys Ile Trp Leu Ile Asp Asp Ser Ile Ala Val Cys Trp 1 5 10 15 Glu Glu Ser Gly Asn 20 <210> 1130 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (5)..(15) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1130 Xaa Gly Glu Tyr Cys Trp Glu Val Asn Glu Asn Val His Val Cys Tyr 1 5 10 15 His Val Pro Asp Ser 20 <210> 1131 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (5)..(14) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1131 Xaa Ile Trp Met Cys Trp Glu Asp Leu Lys Gly Ser Tyr Cys Trp Glu 1 5 10 15 Phe Val Arg Gln Gly 20 <210> 1132 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (8)..(18) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1132 Xaa Leu Asp Gly Gly His Trp Cys Trp Glu Ile Ser Asp Ser Val Met 1 5 10 15 Leu Cys Val Ala Val 20 <210> 1133 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (7)..(18) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1133 Xaa Leu Ser Ile Trp Leu Cys Trp Glu Gly Glu Asp His Thr Phe Thr 1 5 10 15 Val Cys Arg Val Leu 20 <210> 1134 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (7)..(16) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1134 Xaa Pro Gly Val Glu Leu Cys Trp Glu Ala Asn Gly Trp Thr Thr Cys 1 5 10 15 Ile Ser Trp Pro Tyr 20 <210> 1135 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (10)..(19) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1135 Xaa Arg Asp Glu Trp Gln Ile Thr Val Cys Trp Leu Gly Ser Ile Tyr 1 5 10 15 Glu Ala Cys Trp Asp 20 <210> 1136 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (9)..(19) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1136 Xaa Arg Gly Gln Gln Gly Asp His Cys Thr Val Ile Thr Ser Phe Val 1 5 10 15 Thr Leu Cys Lys Glu 20 <210> 1137 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (4)..(14) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1137 Xaa Arg Ser Cys Ile Arg Ile Asn Glu Arg Leu Glu Leu Cys Trp Glu 1 5 10 15 Lys Thr Asp Leu Glu 20 <210> 1138 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (8)..(17) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1138 Xaa Ser Gly Gly Leu Tyr Gln Cys Trp Gly Asp Asp Arg Ile Met Leu 1 5 10 15 Cys Trp Ala Tyr Asp 20 <210> 1139 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (8)..(17) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1139 Xaa Ser Val Gly Ile Trp Leu Cys Trp Met Asp Ser Arg Gly Ser Val 1 5 10 15 Cys His Gln Leu Lys 20 <210> 1140 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (9)..(19) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1140 Xaa Thr Arg Ala Met Gly Ala Ile Cys His Arg Ile Thr Glu His Val 1 5 10 15 Ser Val Cys Tyr Met 20 <210> 1141 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (9)..(19) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1141 Xaa Thr Arg Thr Met Gly Ala Ile Cys His Arg Ile Thr Glu His Val 1 5 10 15 Ser Val Cys Tyr Met 20 <210> 1142 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (5)..(18) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1142 Xaa Val Asp His Cys Thr Pro Leu Ser Arg Glu Arg Ala Gln Val Trp 1 5 10 15 Val Cys Trp Glu Val 20 <210> 1143 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (9)..(20) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1143 Xaa Val Arg Asn Thr Val Trp Val Cys Trp Tyr Glu Arg Ser Ser Thr 1 5 10 15 Arg Glu Trp Cys His 20 <210> 1144 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (7)..(18) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1144 Xaa Val Ser Val Trp Ile Cys Trp Glu Thr Leu Glu Gly Val Pro Leu 1 5 10 15 Glu Cys Lys Leu Trp 20 <210> 1145 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (5)..(15) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1145 Xaa Val Trp Ile Cys Ala Val Ala Ala Arg Gly Pro Asp Ile Cys Tyr 1 5 10 15 Tyr Leu Val Asn Ala 20 <210> 1146 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (9)..(16) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1146 Xaa Trp Gln Trp Glu Val Leu Trp Cys Asn Asp His Asn Thr Val Cys 1 5 10 15 Val Gly Leu Ile Gln 20 <210> 1147 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> DISULFID <222> (8)..(18) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1147 Xaa Trp Tyr Gly His Asp Tyr Cys Phe Lys Phe Ser Arg Glu Ile Trp 1 5 10 15 Ile Cys Gln Met Asp 20 <210> 1148 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1148 Xaa Ala Glu Ile Glu Trp Gly Trp Tyr Val Ser Asp Ala Glu Glu Phe 1 5 10 15 Ile Val Leu Gly His 20 <210> 1149 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1149 Xaa Ala Phe Trp Glu Ala Gly Trp Tyr Asp Ser Val Gly Asn Ser Trp 1 5 10 15 Asn Val Phe Phe Lys 20 <210> 1150 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1150 Xaa Ala Gly Val Ala Val Ser Glu Val Thr Trp Gly Trp Tyr Asn Met 1 5 10 15 Val Asp Asp Thr His 20 <210> 1151 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1151 Xaa Ala Ile Glu Leu Gly Tyr Tyr Ser Gln Ser Thr Asp Ser Ser Ile 1 5 10 15 Ile Leu Trp Gln Glu 20 <210> 1152 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1152 Xaa Ala Ile Glu Val Gly Trp Tyr Tyr Leu Glu Ser Thr Arg His Glu 1 5 10 15 Val Phe Thr Asn Ala 20 <210> 1153 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1153 Xaa Ala Trp Thr Trp Glu Phe Gly Thr Tyr Asn Phe Met Thr Asp Ser 1 5 10 15 Tyr Thr Leu Gln Trp 20 <210> 1154 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1154 Xaa Asp Ser Thr Ile Tyr Val Gly Trp Tyr Ser Tyr Asp His Asp Tyr 1 5 10 15 Asp Ile Trp Gly Tyr 20 <210> 1155 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1155 Xaa Glu His Arg His Thr Arg Ser Lys Asp Pro Tyr Tyr Ser Val Glu 1 5 10 15 Leu Met Trp Glu Phe 20 <210> 1156 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1156 Xaa Glu Ile Glu Val Gly Tyr Glu Thr Phe Glu Ser Gly Glu Ala Val 1 5 10 15 Trp Trp Val Ala Phe 20 <210> 1157 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1157 Xaa Glu Leu Val Leu Val Trp Glu Ser Thr Asp Gly Arg Val Gln Leu 1 5 10 15 Trp Ala Gln Trp Asp 20 <210> 1158 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1158 Xaa Glu Val Arg Trp Glu Leu Gly Ile Glu Ser Arg Phe Ser Gly Trp 1 5 10 15 Tyr Met Val Leu Gly 20 <210> 1159 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1159 Xaa Glu Trp Gln Val Thr Ser Thr Val Trp Ile Gly Trp Glu Leu Gln 1 5 10 15 Met Asp Leu Ala Thr 20 <210> 1160 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1160 Xaa Glu Tyr Ala Val Trp Glu Leu Gly Tyr Tyr Ser Met Trp Glu Asp 1 5 10 15 Asp His Val Ile Ile 20 <210> 1161 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1161 Xaa Phe Asp Val Pro Leu Trp Ala Trp Ser Ser Gly Glu Met Tyr Ile 1 5 10 15 Glu Ile Gly Leu His 20 <210> 1162 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1162 Xaa Phe Gly Val Val Ala Val Gly Tyr Tyr Asp Arg Glu Tyr Asp Lys 1 5 10 15 Trp Thr Leu Ile Ala 20 <210> 1163 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1163 Xaa Phe Ile Val Val Gly Ala Tyr Ser Lys Leu Thr Gly Leu His Ile 1 5 10 15 Gln Trp Gly Tyr Glu 20 <210> 1164 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1164 Xaa Phe Ser Gly Ser Gly Pro Trp Phe Val Tyr Leu Ile Gly Gly Ser 1 5 10 15 Ile Glu Met Gly Tyr 20 <210> 1165 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1165 Xaa Phe Val Ser Leu Trp Trp Glu Thr Ser Asn Gly Arg Gly Glu Ile 1 5 10 15 Ala Arg Trp Ile Ile 20 <210> 1166 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1166 Xaa Gly Ala Ala Trp Phe Ile Thr Leu Asp Gly Gly Thr Val Glu Ile 1 5 10 15 Gly Trp Glu Gln Ile 20 <210> 1167 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1167 Xaa Gly Phe Tyr Trp Glu Val Gly Phe Tyr Asp Tyr Gly Ser Asp Ser 1 5 10 15 Ile Asn Val His Ala 20 <210> 1168 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1168 Xaa Gly His Ser Val Glu Ile Gly Trp Tyr Asn Val Ala Lys Asp Gln 1 5 10 15 Pro Asp Met Tyr Tyr 20 <210> 1169 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1169 Xaa Gly Lys Tyr Leu Leu Leu Asp Phe Thr Phe Trp Leu Thr Lys Glu 1 5 10 15 Val Gly Val Gly Trp 20 <210> 1170 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1170 Xaa Gly Leu Gly Trp Glu Val Gly Trp His Val Leu Glu Ser Ser His 1 5 10 15 Asp Leu Thr Ile His 20 <210> 1171 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1171 Xaa Gly Leu Ile Glu Trp Gly Trp Tyr Ser Arg Gln Glu Asp Gln His 1 5 10 15 Trp Leu Met Gly Thr 20 <210> 1172 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1172 Xaa Gly Arg Trp Leu Ile Gly Leu Ala Pro Gln Ala Glu Val Trp Phe 1 5 10 15 Leu Trp Gln Pro Met 20 <210> 1173 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1173 Xaa Gly Thr Glu Ile Gly Trp Leu Asp Leu Leu Thr Asp His Val Ile 1 5 10 15 Trp Ser Val Thr Ile 20 <210> 1174 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1174 Xaa Gly Thr Gln Glu Arg Gly Ser Lys Arg Met Met Phe Thr Val Glu 1 5 10 15 Leu Trp Trp Glu Pro 20 <210> 1175 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1175 Xaa Gly Trp Phe Met Glu Val Ala Thr Val Leu Gly Val Ile Glu Val 1 5 10 15 Gly Trp Val Val 20 <210> 1176 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1176 Xaa Gly Trp Ile Phe Ile Gly Leu His Ser Tyr His Thr Gly Met Glu 1 5 10 15 Ser Glu Trp Pro Gly 20 <210> 1177 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1177 Xaa His Leu His Tyr Asn Gly Gly Thr Ile Tyr Trp Gly Ser Glu Pro 1 5 10 15 Phe Asn Ala Ser Trp 20 <210> 1178 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1178 Xaa His Met Arg Gly Thr Ala Thr Ser Glu Arg Arg Tyr Trp Ile Glu 1 5 10 15 Val Gly Trp Phe Asp 20 <210> 1179 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1179 Xaa His Met Thr Val Glu Phe Gly Tyr Tyr Trp Val Glu Met Asp Thr 1 5 10 15 Asn Thr Val Ile Trp 20 <210> 1180 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1180 Xaa Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys 1 5 10 15 Leu Gly Met Leu Ile 20 <210> 1181 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1181 Xaa Ile Ser Val Gly Trp Tyr Phe Trp Ala Thr Asp Asn Tyr Lys Glu 1 5 10 15 Phe Gly Asn Thr Leu 20 <210> 1182 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1182 Xaa Lys Phe Lys Arg Trp Glu Ile Gly Phe Met Leu Glu Ser Gly Glu 1 5 10 15 Glu Tyr Val Leu Ala 20 <210> 1183 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1183 Xaa Lys Val Trp Ser Arg Val Gln Ile Ile Arg Gly Gly Trp Ile Glu 1 5 10 15 Val Gly Tyr Glu Phe 20 <210> 1184 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1184 Xaa Leu Gly Val Glu Met Gly Tyr His Val Tyr Gln Thr Gly Glu Asp 1 5 10 15 Tyr Ile Val Leu Thr 20 <210> 1185 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1185 Xaa Leu Gly Val Glu Met Gly Tyr His Val Tyr Gln Thr Gly Gly Asp 1 5 10 15 Tyr Ile Val Leu Thr 20 <210> 1186 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1186 Xaa Leu Ile Glu Ala Gly Tyr His Asp Ile Ala Ser Gln Ser Asp Arg 1 5 10 15 Ile Leu Val Arg Tyr 20 <210> 1187 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1187 Xaa Leu Ile Val Phe Gly Tyr Ser Tyr Ile Glu Thr Glu Glu Glu Phe 1 5 10 15 Ile Ile Ser Leu His 20 <210> 1188 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1188 Xaa Leu Leu Trp His Thr Gly Asp His Ser Val Ser Leu Phe Tyr Glu 1 5 10 15 Val Leu Asp Tyr Pro 20 <210> 1189 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1189 Xaa Leu Trp Met Val Arg Ile Leu Arg Thr Asp Gly Ala Glu Val Val 1 5 10 15 Val Gly Trp Glu Leu 20 <210> 1190 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1190 Xaa Met Gly Leu Trp Tyr Gly Trp Glu Tyr Val Asn Gly Leu Gly Gly 1 5 10 15 His Glu Ile Glu Ile 20 <210> 1191 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1191 Xaa Asn His Val Trp Glu Val Gln Leu Asp Lys Ser Val Trp Ile Gly 1 5 10 15 Trp Glu Trp Ile Asp 20 <210> 1192 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1192 Xaa Asn Ser Ser Asn Ser Asn Gly Gln Lys Phe Arg Tyr Phe Ile Glu 1 5 10 15 Val Gly Trp Tyr His 20 <210> 1193 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1193 Xaa Asn Thr Thr Gly Arg Ile Glu Leu Trp Ile Gln Leu Pro Asp Arg 1 5 10 15 Asp Trp Leu Leu Trp 20 <210> 1194 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1194 Xaa Pro Tyr Phe Val Glu Leu Gly Tyr Glu Gly Tyr Gly Val Phe Tyr 1 5 10 15 Lys Ile Glu Leu Leu 20 <210> 1195 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1195 Xaa Pro Tyr Gly Val Trp Tyr Ser Trp Asp Asn Thr Ser Trp Leu Gln 1 5 10 15 Ile Ser Thr His Val 20 <210> 1196 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1196 Xaa Gln Phe Phe Gly Leu Ile Ser Gly Asp Gly Arg Leu Gln Ile Trp 1 5 10 15 Ile Gly Trp Tyr Glu 20 <210> 1197 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1197 Xaa Gln Gly Lys Tyr Gly Ile Val Ala Trp Gly Trp Val Pro Ser Gly 1 5 10 15 Gly His Arg Tyr Gln 20 <210> 1198 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1198 Xaa Gln Ile Gln Trp Gly Tyr Glu Tyr Ala Ser Gly Trp Gln Asn Trp 1 5 10 15 Trp Glu Arg Ser Asn 20 <210> 1199 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1199 Xaa Gln Val Glu Leu Trp Phe Glu Asp Arg Ser Thr Gly Gln Gln Tyr 1 5 10 15 Arg Leu Ala Thr Ile 20 <210> 1200 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1200 Xaa Gln Val Ser Ser Ile Glu Leu Trp Ala Glu Tyr Gly Asp Val Pro 1 5 10 15 Arg Leu Ile Trp Ser 20 <210> 1201 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1201 Xaa Gln Trp Asp Trp Val Glu Tyr Glu Trp Gly Asn Thr Gly Leu Val 1 5 10 15 Gly Trp Gly Tyr Glu 20 <210> 1202 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1202 Xaa Gln Trp Arg Ile Leu Ile Gly Leu His Glu Met Gly Thr Gly Tyr 1 5 10 15 Asp Leu Val Leu Trp 20 <210> 1203 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1203 Xaa Gln Trp Trp Ser Val Gly Tyr Tyr Asp Phe Glu Gln Asp Val His 1 5 10 15 Val Val Trp Lys Thr 20 <210> 1204 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1204 Xaa Arg Leu Ile Glu Leu Gly Phe Trp Tyr Glu Ile Ala Glu Glu His 1 5 10 15 Val Val Val Trp Ser 20 <210> 1205 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1205 Xaa Arg Arg Ile Thr Leu Gly Trp Tyr Val Tyr Ser Asn Asn Thr Tyr 1 5 10 15 Met Ile Trp Thr Thr 20 <210> 1206 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1206 Xaa Arg Trp Ile Val Tyr Ser His Glu Val Glu Ile Ser Lys Gly Val 1 5 10 15 Trp Leu Gly Tyr Glu 20 <210> 1207 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1207 Xaa Arg Tyr Gly Tyr Ile Val Val Gly Trp Tyr Asp Phe Asn Lys Asp 1 5 10 15 Leu Tyr Thr Arg Phe 20 <210> 1208 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1208 Xaa Ser Gly Ile Ile Leu Gly Trp Tyr Ser Val Tyr Arg Asn Glu Trp 1 5 10 15 Phe Glu Trp Gly Thr 20 <210> 1209 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1209 Xaa Ser Gly Arg Gly Thr Pro Ala Gly Asp His Lys Tyr Ser Ile Glu 1 5 10 15 Ala Phe Tyr Tyr Thr 20 <210> 1210 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1210 Xaa Ser Ile Arg Gln Arg Asp Gln Tyr Thr Ile Glu Leu Tyr Trp Glu 1 5 10 15 Trp Val Asp Ser Pro 20 <210> 1211 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1211 Xaa Ser Leu Ile Trp Ser Ser Asn Thr Ser Gly Arg Tyr Arg Val Glu 1 5 10 15 Leu Trp Ala Glu Arg 20 <210> 1212 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1212 Xaa Ser Leu Ser Arg Ser Asp Glu Ala Lys Leu Leu Trp Arg Ile Glu 1 5 10 15 Phe Gly Trp Glu Tyr 20 <210> 1213 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1213 Xaa Ser Asn Lys Tyr Arg Leu Val Ser Asp Leu Gln Tyr Thr Val Glu 1 5 10 15 Phe Gly Trp Glu Trp 20 <210> 1214 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1214 Xaa Ser Gln Lys Pro Asp Glu Thr Arg Met Ser Arg Tyr Ser Ile Glu 1 5 10 15 Leu Phe Trp Glu Leu 20 <210> 1215 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1215 Xaa Ser Thr Ile Trp Leu Trp Thr Asn Gly Ile Val Glu Val Gly Trp 1 5 10 15 Glu Phe Thr Asp Tyr 20 <210> 1216 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1216 Xaa Ser Val Ser Val Gly Trp Tyr Tyr Thr Val Glu Glu Arg His Tyr 1 5 10 15 Met Leu Trp Leu Gly 20 <210> 1217 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1217 Xaa Ser Val Thr Val Gly Trp Tyr Ser Trp Ile Glu Asp Met Glu Trp 1 5 10 15 Thr Val Tyr Ser Gln 20 <210> 1218 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1218 Xaa Ser Trp Arg Val Glu Ile Gly Trp His Trp Leu Ile Ser Gly Ile 1 5 10 15 Asp Glu Pro Thr Ile 20 <210> 1219 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1219 Xaa Thr Ile Val Ile Gly His Leu Asp Arg Val Ser Gly Val Glu Thr 1 5 10 15 Asp Phe Tyr Ser Val 20 <210> 1220 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1220 Xaa Thr Arg Arg Thr Gly Phe Ser Val Gln Phe Gly Trp Glu Val Ser 1 5 10 15 Ser Gln Tyr Thr His 20 <210> 1221 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1221 Xaa Thr Val Glu Leu Trp Ile Trp Asn Thr Phe Thr Asp His Ser His 1 5 10 15 Met Ile Ala Ser Ile 20 <210> 1222 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1222 Xaa Thr Tyr Val Tyr Trp Glu Val Gly Leu Glu Ser Ala Asn Gly Ala 1 5 10 15 Lys Glu Ile Trp Gln 20 <210> 1223 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1223 Xaa Val Glu Phe Gly Trp Tyr Arg Arg Glu Ser Asp Thr Trp His Ser 1 5 10 15 Trp Gly Lys Val Asn 20 <210> 1224 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1224 Xaa Val Glu Ile Gly Trp His Phe Leu Lys Tyr Glu Lys Glu Leu Val 1 5 10 15 Trp Tyr Met His Gln 20 <210> 1225 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1225 Xaa Val Glu Ile Gly Trp His Phe Leu Asn Tyr Glu Lys Glu Leu Val 1 5 10 15 Trp Tyr Met His Gln 20 <210> 1226 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1226 Xaa Val Glu Val Gly Trp Glu Gln Asp Gly Val Thr Val Trp Thr Val 1 5 10 15 Thr Trp Tyr His Thr 20 <210> 1227 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1227 Xaa Val Glu Val Gly Trp Val Ser Leu Phe Lys Asp Leu Thr Val Phe 1 5 10 15 Lys Glu Trp Ile Pro 20 <210> 1228 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1228 Xaa Val Phe Glu Val Gly Trp Val Thr Ser Asp Gly Arg Val Leu Trp 1 5 10 15 Arg Thr Ile Arg Asn 20 <210> 1229 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1229 Xaa Val Ile Trp Arg Asp Gly Arg Ser Leu Glu Arg Trp Ser Ile Glu 1 5 10 15 Phe Gly Trp Glu Ala 20 <210> 1230 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1230 Xaa Val Arg Pro Lys Glu Ile Arg Lys Arg Pro Leu Phe Tyr Val Glu 1 5 10 15 Leu Phe Trp Glu His 20 <210> 1231 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1231 Xaa Val Val Glu Ile Gly Trp Val Leu Val Ser Ser Leu Gly Asn Glu 1 5 10 15 Lys Val Val Leu Trp 20 <210> 1232 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1232 Xaa Val Tyr Ser Val Glu Ser Gly Trp Tyr Ser Phe Asn Asp Asp Glu 1 5 10 15 Trp Met Ser Phe Tyr 20 <210> 1233 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1233 Xaa Trp Glu Ile Glu Leu Gly Leu Val Met Asn Gly Gln Glu Tyr Met 1 5 10 15 Ile Val Thr Leu Tyr 20 <210> 1234 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1234 Xaa Trp Glu Tyr Trp Glu Val Tyr Thr Ile Gly Pro Val Thr Val Gly 1 5 10 15 Trp Glu Leu Ile Ala 20 <210> 1235 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1235 Xaa Trp Gly Ile Met Glu Leu Gly Met Tyr Trp Tyr Glu Asp Gly Arg 1 5 10 15 His Lys Ala Ile Trp 20 <210> 1236 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1236 Xaa Trp Gly Ile Thr Leu Gly Trp Glu Asp Gly His Gly Asn Glu His 1 5 10 15 Asp Glu Tyr Val Leu 20 <210> 1237 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1237 Xaa Trp Gly Val Val Glu Val Gly Tyr His Phe Val Ala Thr Gly Ser 1 5 10 15 Asn Glu Ala Leu Trp 20 <210> 1238 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1238 Xaa Trp Gly Trp Ile Val Ser Ala Gly Trp His Tyr Ser Ala Met Ala 1 5 10 15 Glu Asp His Pro Trp 20 <210> 1239 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1239 Xaa Trp Ile Phe Thr Trp Ser Ser Gly Asp His Ile Gly Val Ile Glu 1 5 10 15 Met Gly Tyr Glu Ser 20 <210> 1240 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1240 Xaa Trp Ile Val Ile Gly Trp Glu Asp Ala Tyr Gly Arg Ser Val Ile 1 5 10 15 Trp Tyr Lys Val Gly 20 <210> 1241 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1241 Xaa Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr 1 5 10 15 Thr Trp Trp Lys Val 20 <210> 1242 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1242 Xaa Trp Lys Trp Arg Thr Phe Asp Gly Ser Ile Glu Ile Gly Phe Val 1 5 10 15 Ala Val Gln Trp Ser 20 <210> 1243 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1243 Xaa Trp Leu Ile Glu Phe Gly Tyr Met Trp Asn Gly Glu Asn Arg Thr 1 5 10 15 Leu Ala Val Trp Glu 20 <210> 1244 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1244 Xaa Trp Arg Glu Thr Ile Phe Tyr Val Thr Asp Gln Ile Ser Val Val 1 5 10 15 Ile Leu Glu Lys Val 20 <210> 1245 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1245 Xaa Trp Ser Pro Gly Met Lys Glu Ile Glu Leu Gly Ser Thr Gly Ile 1 5 10 15 Tyr Trp Gly Trp Ser 20 <210> 1246 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1246 Xaa Trp Val Glu Phe Gly Tyr Tyr Asp Pro Glu Thr Asp Glu Ser Thr 1 5 10 15 Ile Leu Thr Glu Trp 20 <210> 1247 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1247 Xaa Tyr Ser Ile Val Tyr Gly His Tyr Gln Lys Gln Thr Asn Thr Trp 1 5 10 15 Thr Glu Leu Val Tyr 20 <210> 1248 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1248 Xaa Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp 1 5 10 15 Asn Tyr Met Trp Met 20 <210> 1249 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1249 Xaa Tyr Val Glu Val Gly Tyr Tyr Phe His Thr Thr Asp Asn Glu Val 1 5 10 15 Ile Ile Tyr Ala Asn 20 <210> 1250 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1250 Xaa Tyr Val Glu Val Gly Tyr Tyr Phe Tyr Thr Thr Asp Asn Glu Val 1 5 10 15 Ile Ile Tyr Ala Asn 20 <210> 1251 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1251 Ala Phe Trp Glu Ala Gly Trp Tyr Asp Ser Val Gly Asn Ser Trp Asn 1 5 10 15 Val Phe Phe Lys 20 <210> 1252 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1252 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1253 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1253 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1254 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1254 Tyr Ile Leu Trp Ser Val Tyr Val Gly Pro Gly Ile Glu Val Gly Trp 1 5 10 15 Thr Glu Ser Ala 20 <210> 1255 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1255 Asp Leu Asp Pro Arg Ile Val Leu Val Gly Asn Gly Glu Ile Glu Ile 1 5 10 15 Gly Trp Ser Ile 20 <210> 1256 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1256 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1257 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1257 Ala Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1258 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1258 His Ala Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1259 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1259 His Leu Ala Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1260 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1260 His Leu Tyr Ala Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1261 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1261 His Leu Tyr Leu Ala Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1262 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1262 His Leu Tyr Leu Trp Ala Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1263 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1263 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1264 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1264 His Leu Tyr Leu Trp Gln Arg Ala Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1265 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1265 His Leu Tyr Leu Trp Gln Arg Trp Ala Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1266 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1266 His Leu Tyr Leu Trp Gln Arg Trp Pro Ala Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1267 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1267 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Ala Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1268 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1268 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Ala Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1269 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1269 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Ala Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1270 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1270 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Ala Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1271 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1271 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Ala Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1272 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1272 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Ala 1 5 10 15 Trp Glu Phe Val 20 <210> 1273 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1273 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Ala Glu Phe Val 20 <210> 1274 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1274 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Ala Phe Val 20 <210> 1275 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1275 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Ala Val 20 <210> 1276 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1276 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Ala 20 <210> 1277 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1277 Asp Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1278 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1278 His Asp Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1279 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1279 His Leu Asp Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1280 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1280 His Leu Tyr Asp Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1281 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1281 His Leu Tyr Leu Asp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1282 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1282 His Leu Tyr Leu Trp Asp Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1283 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1283 His Leu Tyr Leu Trp Gln Asp Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1284 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1284 His Leu Tyr Leu Trp Gln Arg Asp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1285 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1285 His Leu Tyr Leu Trp Gln Arg Trp Asp Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1286 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1286 His Leu Tyr Leu Trp Gln Arg Trp Pro Asp Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1287 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1287 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Asp Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1288 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1288 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Asp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1289 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1289 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Asp Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1290 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1290 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Asp Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1291 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1291 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Asp Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1292 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1292 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Asp 1 5 10 15 Trp Glu Phe Val 20 <210> 1293 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1293 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Asp Glu Phe Val 20 <210> 1294 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1294 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Asp Phe Val 20 <210> 1295 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1295 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Asp Val 20 <210> 1296 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1296 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Asp 20 <210> 1297 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1297 Phe Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1298 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1298 His Phe Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1299 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1299 His Leu Phe Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1300 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1300 His Leu Tyr Phe Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1301 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1301 His Leu Tyr Leu Phe Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1302 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1302 His Leu Tyr Leu Trp Phe Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1303 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1303 His Leu Tyr Leu Trp Gln Phe Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1304 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1304 His Leu Tyr Leu Trp Gln Arg Phe Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1305 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1305 His Leu Tyr Leu Trp Gln Arg Trp Phe Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1306 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1306 His Leu Tyr Leu Trp Gln Arg Trp Pro Phe Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1307 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1307 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Phe Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1308 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1308 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Phe Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1309 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1309 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Phe Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1310 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1310 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Phe Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1311 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1311 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Phe Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1312 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1312 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Phe 1 5 10 15 Trp Glu Phe Val 20 <210> 1313 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1313 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Phe Glu Phe Val 20 <210> 1314 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1314 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Phe Phe Val 20 <210> 1315 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1315 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Phe 20 <210> 1316 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1316 Gly Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1317 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1317 His Gly Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1318 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1318 His Leu Gly Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1319 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1319 His Leu Tyr Gly Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1320 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1320 His Leu Tyr Leu Gly Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1321 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1321 His Leu Tyr Leu Trp Gly Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1322 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1322 His Leu Tyr Leu Trp Gln Gly Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1323 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1323 His Leu Tyr Leu Trp Gln Arg Gly Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1324 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1324 His Leu Tyr Leu Trp Gln Arg Trp Gly Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1325 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1325 His Leu Tyr Leu Trp Gln Arg Trp Pro Gly Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1326 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1326 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Gly Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1327 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1327 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Gly Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1328 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1328 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Gly Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1329 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1329 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Gly Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1330 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1330 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Gly Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1331 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1331 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Gly Glu Phe Val 20 <210> 1332 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1332 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Gly Phe Val 20 <210> 1333 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1333 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Gly Val 20 <210> 1334 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1334 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Gly 20 <210> 1335 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1335 Lys Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1336 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1336 His Lys Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1337 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1337 His Leu Lys Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1338 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1338 His Leu Tyr Lys Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1339 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1339 His Leu Tyr Leu Lys Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1340 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1340 His Leu Tyr Leu Trp Lys Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1341 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1341 His Leu Tyr Leu Trp Gln Lys Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1342 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1342 His Leu Tyr Leu Trp Gln Arg Lys Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1343 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1343 His Leu Tyr Leu Trp Gln Arg Trp Lys Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1344 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1344 His Leu Tyr Leu Trp Gln Arg Trp Pro Lys Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1345 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1345 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Lys Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1346 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1346 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Lys Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1347 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1347 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Lys Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1348 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1348 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Lys Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1349 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1349 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Lys Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1350 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1350 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Lys 1 5 10 15 Trp Glu Phe Val 20 <210> 1351 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1351 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Lys Glu Phe Val 20 <210> 1352 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1352 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Lys Phe Val 20 <210> 1353 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1353 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Lys Val 20 <210> 1354 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1354 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Lys 20 <210> 1355 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1355 Leu Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1356 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1356 His Leu Leu Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1357 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1357 His Leu Tyr Leu Leu Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1358 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1358 His Leu Tyr Leu Trp Leu Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1359 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1359 His Leu Tyr Leu Trp Gln Leu Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1360 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1360 His Leu Tyr Leu Trp Gln Arg Leu Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1361 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1361 His Leu Tyr Leu Trp Gln Arg Trp Leu Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1362 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1362 His Leu Tyr Leu Trp Gln Arg Trp Pro Leu Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1363 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1363 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Leu Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1364 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1364 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Leu Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1365 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1365 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Leu Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1366 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1366 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Leu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1367 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1367 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Leu Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1368 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1368 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Leu 1 5 10 15 Trp Glu Phe Val 20 <210> 1369 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1369 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Leu Glu Phe Val 20 <210> 1370 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1370 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Leu Phe Val 20 <210> 1371 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1371 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Leu Val 20 <210> 1372 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1372 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Leu 20 <210> 1373 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1373 Ser Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1374 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1374 His Ser Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1375 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1375 His Leu Ser Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1376 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1376 His Leu Tyr Ser Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1377 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1377 His Leu Tyr Leu Ser Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1378 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1378 His Leu Tyr Leu Trp Ser Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1379 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1379 His Leu Tyr Leu Trp Gln Ser Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1380 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1380 His Leu Tyr Leu Trp Gln Arg Ser Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1381 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1381 His Leu Tyr Leu Trp Gln Arg Trp Ser Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1382 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1382 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Ser Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1383 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1383 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Ser Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1384 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1384 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Ser Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1385 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1385 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Ser Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1386 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1386 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Ser Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1387 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1387 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Ser 1 5 10 15 Trp Glu Phe Val 20 <210> 1388 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1388 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Ser Glu Phe Val 20 <210> 1389 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1389 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Ser Phe Val 20 <210> 1390 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1390 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Ser Val 20 <210> 1391 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1391 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Ser 20 <210> 1392 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1392 Pro Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1393 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1393 His Pro Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1394 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1394 His Leu Pro Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1395 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1395 His Leu Tyr Pro Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1396 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1396 His Leu Tyr Leu Pro Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1397 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1397 His Leu Tyr Leu Trp Pro Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1398 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1398 His Leu Tyr Leu Trp Gln Pro Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1399 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1399 His Leu Tyr Leu Trp Gln Arg Pro Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1400 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1400 His Leu Tyr Leu Trp Gln Arg Trp Pro Pro Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1401 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1401 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Pro Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1402 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1402 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Pro Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1403 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1403 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Pro Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1404 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1404 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Pro Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 1405 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1405 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Pro 1 5 10 15 Trp Glu Phe Val 20 <210> 1406 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1406 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Pro Glu Phe Val 20 <210> 1407 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1407 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Pro Phe Val 20 <210> 1408 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1408 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Pro Val 20 <210> 1409 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1409 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Pro 20 <210> 1410 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 1410 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp <210> 1411 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 1411 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu 1 5 10 <210> 1412 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 1412 His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro 1 5 10 <210> 1413 <211> 8 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> C-terminal amidation <400> 1413 His Leu Tyr Leu Trp Gln Arg Trp 1 5 <210> 1414 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 1414 Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly Trp Glu Phe 1 5 10 15 Val <210> 1415 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 1415 Arg Trp Pro Ser Pro Trp Val Glu Val Gly Trp Glu Phe Val 1 5 10 <210> 1416 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 1416 Ser Pro Trp Val Glu Val Gly Trp Glu Phe Val 1 5 10 <210> 1417 <211> 8 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> C-terminal amidation <400> 1417 Val Glu Val Gly Trp Glu Phe Val 1 5 <210> 1418 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 1418 Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly Trp 1 5 10 <210> 1419 <211> 8 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> C-terminal amidation <400> 1419 Arg Trp Pro Ser Pro Trp Val Glu 1 5 <210> 1420 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1420 Ala Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1421 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1421 Arg Ala Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1422 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1422 Arg Pro Ala Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1423 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1423 Arg Pro Thr Ala Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1424 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1424 Arg Pro Thr Thr Ala Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1425 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1425 Arg Pro Thr Thr Leu Ala Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1426 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1426 Arg Pro Thr Thr Leu Ile Ala Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1427 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1427 Arg Pro Thr Thr Leu Ile Arg Ala Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1428 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1428 Arg Pro Thr Thr Leu Ile Arg Leu Ala Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1429 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1429 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Ala Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1430 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1430 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ala Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1431 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1431 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Ala Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1432 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1432 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ala Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1433 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1433 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Ala Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1434 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1434 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ala 1 5 10 15 Gly Trp Glu Ile 20 <210> 1435 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1435 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Ala Trp Glu Ile 20 <210> 1436 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1436 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Ala Glu Ile 20 <210> 1437 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1437 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Ala Ile 20 <210> 1438 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1438 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ala 20 <210> 1439 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1439 Asp Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1440 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1440 Arg Asp Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1441 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1441 Arg Pro Asp Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1442 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1442 Arg Pro Thr Asp Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1443 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1443 Arg Pro Thr Thr Asp Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1444 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1444 Arg Pro Thr Thr Leu Asp Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1445 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1445 Arg Pro Thr Thr Leu Ile Asp Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1446 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1446 Arg Pro Thr Thr Leu Ile Arg Asp Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1447 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1447 Arg Pro Thr Thr Leu Ile Arg Leu Asp Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1448 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1448 Arg Pro Thr Thr Leu Ile Arg Leu Gly Asp Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1449 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1449 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asp Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1450 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1450 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Asp Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1451 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1451 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Asp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1452 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1452 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Asp Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1453 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1453 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Asp Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1454 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1454 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Asp 1 5 10 15 Gly Trp Glu Ile 20 <210> 1455 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1455 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Asp Trp Glu Ile 20 <210> 1456 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1456 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Asp Glu Ile 20 <210> 1457 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1457 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Asp Ile 20 <210> 1458 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1458 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Asp 20 <210> 1459 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1459 Phe Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1460 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1460 Arg Phe Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1461 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1461 Arg Pro Phe Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1462 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1462 Arg Pro Thr Phe Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1463 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1463 Arg Pro Thr Thr Phe Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1464 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1464 Arg Pro Thr Thr Leu Phe Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1465 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1465 Arg Pro Thr Thr Leu Ile Phe Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1466 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1466 Arg Pro Thr Thr Leu Ile Arg Phe Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1467 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1467 Arg Pro Thr Thr Leu Ile Arg Leu Phe Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1468 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1468 Arg Pro Thr Thr Leu Ile Arg Leu Gly Phe Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1469 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1469 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Phe Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1470 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1470 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Phe Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1471 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1471 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Phe Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1472 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1472 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Phe Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1473 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1473 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Phe Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1474 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1474 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Phe 1 5 10 15 Gly Trp Glu Ile 20 <210> 1475 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1475 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Phe Trp Glu Ile 20 <210> 1476 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1476 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Phe Glu Ile 20 <210> 1477 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1477 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Phe Ile 20 <210> 1478 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1478 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Phe 20 <210> 1479 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1479 Gly Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1480 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1480 Arg Gly Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1481 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1481 Arg Pro Gly Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1482 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1482 Arg Pro Thr Gly Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1483 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1483 Arg Pro Thr Thr Gly Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1484 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1484 Arg Pro Thr Thr Leu Gly Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1485 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1485 Arg Pro Thr Thr Leu Ile Gly Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1486 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1486 Arg Pro Thr Thr Leu Ile Arg Gly Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1487 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1487 Arg Pro Thr Thr Leu Ile Arg Leu Gly Gly Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1488 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1488 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Gly Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1489 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1489 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Gly Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1490 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1490 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Gly Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1491 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1491 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Gly Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1492 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1492 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Gly Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1493 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1493 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Gly 1 5 10 15 Gly Trp Glu Ile 20 <210> 1494 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1494 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Gly Glu Ile 20 <210> 1495 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1495 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Gly Ile 20 <210> 1496 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1496 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Gly 20 <210> 1497 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1497 Lys Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1498 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1498 Arg Lys Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1499 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1499 Arg Pro Lys Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1500 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1500 Arg Pro Thr Lys Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1501 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1501 Arg Pro Thr Thr Lys Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1502 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1502 Arg Pro Thr Thr Leu Lys Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1503 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1503 Arg Pro Thr Thr Leu Ile Lys Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1504 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1504 Arg Pro Thr Thr Leu Ile Arg Lys Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1505 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1505 Arg Pro Thr Thr Leu Ile Arg Leu Lys Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1506 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1506 Arg Pro Thr Thr Leu Ile Arg Leu Gly Lys Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1507 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1507 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Lys Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1508 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1508 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Lys Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1509 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1509 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Lys Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1510 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1510 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Lys Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1511 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1511 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Lys Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1512 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1512 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Lys 1 5 10 15 Gly Trp Glu Ile 20 <210> 1513 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1513 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Lys Trp Glu Ile 20 <210> 1514 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1514 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Lys Glu Ile 20 <210> 1515 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1515 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Lys Ile 20 <210> 1516 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1516 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Lys 20 <210> 1517 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1517 Leu Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1518 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1518 Arg Leu Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1519 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1519 Arg Pro Leu Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1520 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1520 Arg Pro Thr Leu Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1521 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1521 Arg Pro Thr Thr Leu Leu Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1522 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1522 Arg Pro Thr Thr Leu Ile Leu Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1523 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1523 Arg Pro Thr Thr Leu Ile Arg Leu Leu Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1524 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1524 Arg Pro Thr Thr Leu Ile Arg Leu Gly Leu Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1525 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1525 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Leu Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1526 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1526 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Leu Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1527 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1527 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Leu Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1528 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1528 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Leu Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1529 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1529 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Leu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1530 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1530 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Leu 1 5 10 15 Gly Trp Glu Ile 20 <210> 1531 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1531 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Leu Trp Glu Ile 20 <210> 1532 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1532 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Leu Glu Ile 20 <210> 1533 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1533 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Leu Ile 20 <210> 1534 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1534 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Leu 20 <210> 1535 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1535 Ser Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1536 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1536 Arg Ser Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1537 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1537 Arg Pro Ser Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1538 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1538 Arg Pro Thr Ser Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1539 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1539 Arg Pro Thr Thr Ser Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1540 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1540 Arg Pro Thr Thr Leu Ser Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1541 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1541 Arg Pro Thr Thr Leu Ile Ser Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1542 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1542 Arg Pro Thr Thr Leu Ile Arg Ser Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1543 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1543 Arg Pro Thr Thr Leu Ile Arg Leu Ser Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1544 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1544 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ser Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1545 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1545 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Ser Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1546 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1546 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Ser Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1547 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1547 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ser Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1548 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1548 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Ser Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1549 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1549 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ser 1 5 10 15 Gly Trp Glu Ile 20 <210> 1550 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1550 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Ser Trp Glu Ile 20 <210> 1551 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1551 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Ser Glu Ile 20 <210> 1552 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1552 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Ser Ile 20 <210> 1553 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1553 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ser 20 <210> 1554 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1554 Pro Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1555 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1555 Arg Pro Pro Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1556 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1556 Arg Pro Thr Pro Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1557 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1557 Arg Pro Thr Thr Pro Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1558 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1558 Arg Pro Thr Thr Leu Pro Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1559 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1559 Arg Pro Thr Thr Leu Ile Pro Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1560 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1560 Arg Pro Thr Thr Leu Ile Arg Pro Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1561 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1561 Arg Pro Thr Thr Leu Ile Arg Leu Pro Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1562 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1562 Arg Pro Thr Thr Leu Ile Arg Leu Gly Pro Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1563 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1563 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Pro Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1564 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1564 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Pro Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1565 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1565 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Pro Ile Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1566 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1566 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Pro Glu Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1567 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1567 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Pro Ile 1 5 10 15 Gly Trp Glu Ile 20 <210> 1568 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1568 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Pro 1 5 10 15 Gly Trp Glu Ile 20 <210> 1569 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1569 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Pro Trp Glu Ile 20 <210> 1570 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1570 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Pro Glu Ile 20 <210> 1571 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1571 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Pro Ile 20 <210> 1572 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1572 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly Trp Glu Pro 20 <210> 1573 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 1573 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile 1 5 10 15 Gly <210> 1574 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 1574 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile 1 5 10 <210> 1575 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 1575 Arg Pro Thr Thr Leu Ile Arg Leu Gly Ala Asn 1 5 10 <210> 1576 <211> 8 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> C-terminal amidation <400> 1576 Arg Pro Thr Thr Leu Ile Arg Leu 1 5 <210> 1577 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 1577 Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile Gly Trp Glu 1 5 10 15 Ile <210> 1578 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 1578 Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile Gly Trp Glu Ile 1 5 10 <210> 1579 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 1579 Ala Asn Ser Trp Ile Glu Ile Gly Trp Glu Ile 1 5 10 <210> 1580 <211> 8 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> C-terminal amidation <400> 1580 Trp Ile Glu Ile Gly Trp Glu Ile 1 5 <210> 1581 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 1581 Thr Leu Ile Arg Leu Gly Ala Asn Ser Trp Ile Glu Ile Gly 1 5 10 <210> 1582 <211> 8 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> C-terminal amidation <400> 1582 Arg Leu Gly Ala Asn Ser Trp Ile 1 5 <210> 1583 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1583 Ala Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1584 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1584 Trp Ala Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1585 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1585 Trp Lys Ala Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1586 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1586 Trp Lys Ile Ala Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1587 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1587 Trp Lys Ile Ile Ala Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1588 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1588 Trp Lys Ile Ile Val Ala Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1589 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1589 Trp Lys Ile Ile Val Gly Ala Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1590 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1590 Trp Lys Ile Ile Val Gly Trp Ala Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1591 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1591 Trp Lys Ile Ile Val Gly Trp Glu Ala Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1592 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1592 Trp Lys Ile Ile Val Gly Trp Glu Leu Ala Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1593 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1593 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Ala Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1594 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1594 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Ala Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1595 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1595 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Ala Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1596 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1596 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Ala Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1597 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1597 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Ala Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1598 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1598 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Ala 1 5 10 15 Trp Trp Lys Val 20 <210> 1599 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1599 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Ala Trp Lys Val 20 <210> 1600 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1600 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Ala Lys Val 20 <210> 1601 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1601 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Ala Val 20 <210> 1602 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1602 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Ala 20 <210> 1603 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1603 Asp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1604 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1604 Trp Asp Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1605 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1605 Trp Lys Asp Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1606 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1606 Trp Lys Ile Asp Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1607 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1607 Trp Lys Ile Ile Asp Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1608 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1608 Trp Lys Ile Ile Val Asp Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1609 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1609 Trp Lys Ile Ile Val Gly Asp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1610 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1610 Trp Lys Ile Ile Val Gly Trp Asp Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1611 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1611 Trp Lys Ile Ile Val Gly Trp Glu Asp Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1612 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1612 Trp Lys Ile Ile Val Gly Trp Glu Leu Asp Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1613 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1613 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Asp Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1614 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1614 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Asp Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1615 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1615 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Asp Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1616 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1616 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Asp Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1617 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1617 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Asp 1 5 10 15 Trp Trp Lys Val 20 <210> 1618 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1618 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Asp Trp Lys Val 20 <210> 1619 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1619 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Asp Lys Val 20 <210> 1620 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1620 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Asp Val 20 <210> 1621 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1621 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Asp 20 <210> 1622 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1622 Phe Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1623 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1623 Trp Phe Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1624 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1624 Trp Lys Phe Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1625 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1625 Trp Lys Ile Phe Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1626 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1626 Trp Lys Ile Ile Phe Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1627 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1627 Trp Lys Ile Ile Val Phe Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1628 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1628 Trp Lys Ile Ile Val Gly Phe Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1629 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1629 Trp Lys Ile Ile Val Gly Trp Phe Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1630 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1630 Trp Lys Ile Ile Val Gly Trp Glu Phe Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1631 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1631 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Phe Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1632 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1632 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Phe Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1633 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1633 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Phe Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1634 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1634 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Phe Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1635 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1635 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Phe Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1636 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1636 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Phe 1 5 10 15 Trp Trp Lys Val 20 <210> 1637 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1637 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Phe Trp Lys Val 20 <210> 1638 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1638 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Phe Lys Val 20 <210> 1639 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1639 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Phe Val 20 <210> 1640 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1640 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Phe 20 <210> 1641 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1641 Gly Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1642 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1642 Trp Gly Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1643 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1643 Trp Lys Gly Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1644 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1644 Trp Lys Ile Gly Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1645 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1645 Trp Lys Ile Ile Gly Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1646 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1646 Trp Lys Ile Ile Val Gly Gly Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1647 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1647 Trp Lys Ile Ile Val Gly Trp Gly Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1648 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1648 Trp Lys Ile Ile Val Gly Trp Glu Gly Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1649 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1649 Trp Lys Ile Ile Val Gly Trp Glu Leu Gly Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1650 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1650 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Gly Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1651 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1651 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Gly Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1652 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1652 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Gly Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1653 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1653 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Gly Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1654 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1654 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Gly 1 5 10 15 Trp Trp Lys Val 20 <210> 1655 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1655 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Gly Trp Lys Val 20 <210> 1656 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1656 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Gly Lys Val 20 <210> 1657 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1657 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Gly Val 20 <210> 1658 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1658 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Gly 20 <210> 1659 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1659 Lys Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1660 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1660 Trp Lys Lys Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1661 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1661 Trp Lys Ile Lys Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1662 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1662 Trp Lys Ile Ile Lys Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1663 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1663 Trp Lys Ile Ile Val Lys Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1664 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1664 Trp Lys Ile Ile Val Gly Lys Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1665 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1665 Trp Lys Ile Ile Val Gly Trp Lys Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1666 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1666 Trp Lys Ile Ile Val Gly Trp Glu Lys Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1667 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1667 Trp Lys Ile Ile Val Gly Trp Glu Leu Lys Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1668 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1668 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Lys Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1669 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1669 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Lys Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1670 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1670 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Lys Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1671 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1671 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Lys Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1672 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1672 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Lys Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1673 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1673 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Lys 1 5 10 15 Trp Trp Lys Val 20 <210> 1674 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1674 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Lys Trp Lys Val 20 <210> 1675 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1675 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Lys Lys Val 20 <210> 1676 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1676 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Lys 20 <210> 1677 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1677 Leu Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1678 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1678 Trp Leu Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1679 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1679 Trp Lys Leu Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1680 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1680 Trp Lys Ile Leu Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1681 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1681 Trp Lys Ile Ile Leu Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1682 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1682 Trp Lys Ile Ile Val Leu Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1683 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1683 Trp Lys Ile Ile Val Gly Leu Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1684 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1684 Trp Lys Ile Ile Val Gly Trp Leu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1685 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1685 Trp Lys Ile Ile Val Gly Trp Glu Leu Leu Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1686 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1686 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Leu Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1687 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1687 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Leu Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1688 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1688 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Leu Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1689 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1689 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Leu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1690 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1690 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Leu Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1691 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1691 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Leu 1 5 10 15 Trp Trp Lys Val 20 <210> 1692 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1692 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Leu Trp Lys Val 20 <210> 1693 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1693 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Leu Lys Val 20 <210> 1694 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1694 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Leu Val 20 <210> 1695 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1695 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Leu 20 <210> 1696 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1696 Ser Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1697 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1697 Trp Ser Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1698 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1698 Trp Lys Ser Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1699 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1699 Trp Lys Ile Ser Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1700 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1700 Trp Lys Ile Ile Ser Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1701 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1701 Trp Lys Ile Ile Val Ser Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1702 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1702 Trp Lys Ile Ile Val Gly Ser Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1703 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1703 Trp Lys Ile Ile Val Gly Trp Ser Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1704 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1704 Trp Lys Ile Ile Val Gly Trp Glu Ser Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1705 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1705 Trp Lys Ile Ile Val Gly Trp Glu Leu Ser Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1706 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1706 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Ser Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1707 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1707 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Ser Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1708 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1708 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Ser Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1709 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1709 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Ser Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1710 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1710 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Ser Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1711 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1711 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Ser 1 5 10 15 Trp Trp Lys Val 20 <210> 1712 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1712 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Ser Trp Lys Val 20 <210> 1713 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1713 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Ser Lys Val 20 <210> 1714 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1714 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Ser Val 20 <210> 1715 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1715 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Ser 20 <210> 1716 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1716 Pro Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1717 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1717 Trp Pro Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1718 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1718 Trp Lys Pro Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1719 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1719 Trp Lys Ile Pro Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1720 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1720 Trp Lys Ile Ile Pro Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1721 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1721 Trp Lys Ile Ile Val Pro Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1722 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1722 Trp Lys Ile Ile Val Gly Pro Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1723 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1723 Trp Lys Ile Ile Val Gly Trp Pro Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1724 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1724 Trp Lys Ile Ile Val Gly Trp Glu Pro Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1725 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1725 Trp Lys Ile Ile Val Gly Trp Glu Leu Pro Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1726 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1726 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Pro Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1727 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1727 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Pro Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1728 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1728 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Pro Glu Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1729 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1729 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Pro Thr Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1730 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1730 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Pro Thr 1 5 10 15 Trp Trp Lys Val 20 <210> 1731 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1731 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Pro 1 5 10 15 Trp Trp Lys Val 20 <210> 1732 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1732 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Pro Trp Lys Val 20 <210> 1733 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1733 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Pro Lys Val 20 <210> 1734 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1734 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Pro Val 20 <210> 1735 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1735 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp Trp Lys Pro 20 <210> 1736 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 1736 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr 1 5 10 15 Trp <210> 1737 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 1737 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu 1 5 10 <210> 1738 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 1738 Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp 1 5 10 <210> 1739 <211> 8 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> C-terminal amidation <400> 1739 Trp Lys Ile Ile Val Gly Trp Glu 1 5 <210> 1740 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 1740 Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr Trp Trp Lys 1 5 10 15 Val <210> 1741 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 1741 Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr Trp Trp Lys Val 1 5 10 <210> 1742 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 1742 Phe Asp Thr Gly Glu Thr Thr Trp Trp Lys Val 1 5 10 <210> 1743 <211> 8 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> C-terminal amidation <400> 1743 Gly Glu Thr Thr Trp Trp Lys Val 1 5 <210> 1744 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 1744 Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr Thr Trp 1 5 10 <210> 1745 <211> 8 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (8)..(8) <223> C-terminal amidation <400> 1745 Trp Glu Leu Phe Asp Thr Gly Glu 1 5 <210> 1746 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1746 Asp Phe Gly Asn Glu Asn Lys Trp Gly Ser Val Trp Ala Val Ser Phe 1 5 10 15 Ala Phe Trp Tyr 20 <210> 1747 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1747 Val Phe Ala Asn Gly Lys Ser Gly Trp Trp Phe Tyr Asn Phe Glu Trp 1 5 10 15 Asp Val Ala Ser 20 <210> 1748 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1748 Trp Leu Glu Leu Tyr Ser Val Val Phe Arg Pro Pro Glu Gln Gly Trp 1 5 10 15 His Val Trp Trp 20 <210> 1749 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1749 Trp His Gln Ser Glu Tyr Pro Val Val Phe Gly Leu Trp Pro Arg Glu 1 5 10 15 Trp Trp Leu Val 20 <210> 1750 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1750 Gly Gly Leu Ile Thr Thr Trp Asn Ile Glu Trp Glu Leu Arg Arg Ile 1 5 10 15 Ile Ala Pro Ser 20 <210> 1751 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1751 Pro Ala Thr Gly Leu Ile Ile Trp Ser Glu Thr Arg Gly Ile Arg Leu 1 5 10 15 Ile Trp Asn Glu 20 <210> 1752 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1752 Thr Ser Gly Ser Ala Trp Gly Trp Glu Ile Pro Val Val Glu Tyr Gly 1 5 10 15 Ile Val Tyr Leu 20 <210> 1753 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1753 Val Ala Tyr Val Trp Thr Leu Tyr Val Gly Ile Ser Glu Glu Ser Pro 1 5 10 15 Gly Ile Gly Trp 20 <210> 1754 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1754 Thr Gly Ile Val Leu Gly Trp Trp Thr Asp Ile Lys Thr Glu Phe Glu 1 5 10 15 Val Trp Trp Lys 20 <210> 1755 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1755 Lys Trp Leu Trp Thr Lys Gly Trp Val Asp Thr Phe Val Ile Glu Ile 1 5 10 15 Thr Gly Trp Glu 20 <210> 1756 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1756 Leu Asp Gly Ile Ser Leu Gly Gly Pro Val Ile Trp Val Asn Ile Glu 1 5 10 15 Asp Ile Glu Arg 20 <210> 1757 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1757 Gly Leu Val Ile Ile Glu Pro Asp Leu Ile Val Asp Ser Gly Gly Trp 1 5 10 15 Glu Asn Arg Ile 20 <210> 1758 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1758 Xaa Gly Gln Ile Glu Trp Gly Phe Tyr Asp His Thr Thr Asn Gln Tyr 1 5 10 15 Trp Ser Met Asp Val 20 <210> 1759 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1759 Xaa Leu His Glu Leu Gly Arg Ile Gln Thr Glu Gln Tyr Ser Ile Glu 1 5 10 15 Ile Tyr Tyr Val His 20 <210> 1760 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1760 Xaa His Arg Ile Glu Ile Trp Trp Tyr Asn Ser Gly Thr Asn Lys His 1 5 10 15 Gly Leu Val His Thr 20 <210> 1761 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1761 Xaa Gly Arg His Thr Asn Asp Ile Asn Lys Met Arg Arg Ala Val Gln 1 5 10 15 Ala Leu Phe Glu Asn 20 <210> 1762 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1762 Xaa Trp Gly Leu Gly Phe Tyr Asp Val Asn Thr Trp Arg His Thr Pro 1 5 10 15 Ile Ala Phe Lys Thr 20 <210> 1763 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1763 Xaa Val Trp Ile Ser Leu Gly Trp Tyr Asp Met Val Asn Asp Arg His 1 5 10 15 Ser Ser Leu Ile Met 20 <210> 1764 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1764 Xaa Arg Lys Glu Tyr Glu Trp Ala Glu Arg Glu Gly Trp Lys Thr Thr 1 5 10 15 Leu Ser Met Phe Leu 20 <210> 1765 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1765 Xaa Ala Tyr Met Trp Met Ile Gly Met Tyr Tyr Thr Glu Leu Asp Thr 1 5 10 15 His Lys Val Val Ala 20 <210> 1766 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1766 Xaa Thr Val Asn Ser Ser Val Asp Trp Gly Tyr Glu Met Tyr Ala Ser 1 5 10 15 Gln Trp Arg His Asn 20 <210> 1767 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1767 Xaa His Val His Leu Thr Tyr Gln Ile Glu Val Gly Trp Glu Tyr Val 1 5 10 15 Lys Glu Ile Tyr Lys 20 <210> 1768 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1768 Xaa Arg Leu Arg Ile Glu Leu Gly Val Ile Val Asp Gly Gln Val Leu 1 5 10 15 Ile Trp Lys Val Leu 20 <210> 1769 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1769 Xaa His Gly Val Glu Val Gly Phe Trp Asp Thr Val Met Asp Lys Val 1 5 10 15 Tyr Ile Val His Met 20 <210> 1770 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1770 Xaa Ile Trp Val Gly Tyr Phe Asn Tyr Glu Asp Asn Tyr Trp Ser Gln 1 5 10 15 Ile Gly Ser Met Thr 20 <210> 1771 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1771 Xaa Ser His Arg Trp Arg Arg Leu Arg Glu Leu Lys Trp Tyr Val Glu 1 5 10 15 Phe Gly Trp Glu Val 20 <210> 1772 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1772 Xaa Tyr Glu Trp Val Asp Arg Ala Gly Glu Met Ala Leu Phe Thr Leu 1 5 10 15 Arg Asp Phe Tyr Ala 20 <210> 1773 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1773 Xaa Ile Phe Thr Val Glu Leu Trp Trp Asp Ser Thr Gln Gly Glu Gly 1 5 10 15 Met Ile Trp Ser Ile 20 <210> 1774 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1774 Xaa Trp Val Ser Leu Gly Trp Tyr Asp Ser Arg Ser Val Asn Glu Gln 1 5 10 15 Trp Tyr Ser Val Trp 20 <210> 1775 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1775 Xaa Leu Trp Val Phe Arg Arg His Ser Asp Lys Asn Gly Ile Tyr Glu 1 5 10 15 Val Gly Tyr Glu Val 20 <210> 1776 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1776 Xaa Gly Val Thr Ala Gly His Tyr Tyr Ile Asp Ile Asn Thr Tyr Lys 1 5 10 15 Pro Phe Glu Ser Gly 20 <210> 1777 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1777 Xaa Trp Leu Val Val Arg Val Asn Asn Gln Ile Ser Val Trp Trp Asp 1 5 10 15 Val Gly Phe Thr Thr 20 <210> 1778 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1778 Xaa Glu Asp Pro Trp Glu Trp Gln Val Trp Ile Ser Val Asn Gly Thr 1 5 10 15 Glu Ile Arg Leu His 20 <210> 1779 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1779 Xaa Trp Arg Phe Trp His Ala His Glu Asn Ser Gly Phe Leu Val Glu 1 5 10 15 Ile Gly Tyr Glu Arg 20 <210> 1780 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1780 Xaa Glu Lys Thr Ile Glu Val Gly Leu Tyr Phe Lys Lys Glu Asp Val 1 5 10 15 Tyr Lys Pro Met Gly 20 <210> 1781 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1781 Xaa Lys Leu Ile Arg Val Gly Phe Tyr Asn Leu Asn Thr Asn Thr His 1 5 10 15 Thr Tyr Trp Glu Asp 20 <210> 1782 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1782 Xaa Ser Ile Val Ile Met Gly Phe Tyr Asn Tyr Asn Ser Asp Thr Tyr 1 5 10 15 Lys Leu Trp Ser Met 20 <210> 1783 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1783 Xaa Leu Ala Ile Glu Met Trp Trp Gln Ser Val Ala Glu Thr Glu His 1 5 10 15 Lys Gly Leu Ile Trp 20 <210> 1784 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1784 Xaa Ala Val Trp Pro Glu Arg Arg Val Thr Val Val Tyr Tyr Arg Trp 1 5 10 15 His Val Pro Ala Lys 20 <210> 1785 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1785 Xaa Gly Asn Arg Asn Leu Asp Trp Leu His Thr Tyr Ser Val Glu Leu 1 5 10 15 Phe Trp Glu Leu Asn 20 <210> 1786 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1786 Xaa Gly Ile Thr Val Gly Tyr Met Asn Met Asp Ser Gly Ala Tyr Leu 1 5 10 15 Ile Ile Trp Ser Arg 20 <210> 1787 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1787 Xaa Thr Trp Asn Ser Arg Val Tyr Leu Gly Met Asn Tyr Glu Val Glu 1 5 10 15 Ile Gly Tyr Glu Gln 20 <210> 1788 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1788 Xaa Glu Val Phe Leu Leu Met Leu Trp Tyr Asp Ala Lys Gly Asn Glu 1 5 10 15 Val Arg Met Arg Ile 20 <210> 1789 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1789 Xaa His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr 1 5 10 15 Ala Tyr Ser Ser Tyr 20 <210> 1790 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1790 Xaa Ser Ile Val Val Gly Trp Tyr Trp Arg Ala Thr Asp Arg His Ile 1 5 10 15 Arg Phe His Arg Ser 20 <210> 1791 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1791 Xaa Trp Val Val Ala Thr Gly Ser Asn Trp Glu Leu Trp Val Glu Pro 1 5 10 15 Trp Asn Gly Lys Ala 20 <210> 1792 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1792 Xaa Val Val Trp Arg Ser Ala Asn Arg Met Ile Val Phe Gly Trp Glu 1 5 10 15 Tyr His Asp Asn Tyr 20 <210> 1793 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1793 Xaa Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp 1 5 10 15 Asn Tyr Val Trp Met 20 <210> 1794 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1794 Xaa Tyr Val Glu Val Gly Tyr Tyr Phe His Thr Thr Gly Asn Glu Val 1 5 10 15 Ile Ile Tyr Ala Asn 20 <210> 1795 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1795 Xaa Ser Ile Val Ile Met Gly Phe Tyr Asn Tyr Asn Ser Asp Thr Tyr 1 5 10 15 Lys Leu Trp Gly Met 20 <210> 1796 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1796 Xaa Tyr Thr Val Glu Val Gly Trp His Thr Val His Ala Gly Arg Asp 1 5 10 15 Asn Tyr Met Trp Val 20 <210> 1797 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1797 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Lys Asp Asn 1 5 10 15 Ser Met Trp Met 20 <210> 1798 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1798 Xaa Thr Trp Val Glu Ile Gly Phe Tyr Asp Arg Ile Asn Asp Arg Ile 1 5 10 15 Trp Arg Leu Tyr Ser 20 <210> 1799 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1799 Xaa Tyr Arg Thr Asn Arg Ala Ile Val Thr Val Gly Trp Ala Ile Ala 1 5 10 15 Ser Thr Tyr Thr His 20 <210> 1800 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1800 Xaa Tyr Ala Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp 1 5 10 15 Asn Tyr Met Trp Met 20 <210> 1801 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1801 Xaa Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp 1 5 10 15 Asn Tyr Met Trp Val 20 <210> 1802 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1802 Xaa Tyr Val Glu Val Gly Tyr Tyr Phe His Thr Thr Asp Asn Glu Val 1 5 10 15 Val Ile Tyr Ala Asn 20 <210> 1803 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1803 Xaa Tyr Thr Val Glu Val Gly Trp His Thr Ala His Thr Gly Arg Asp 1 5 10 15 Asn Tyr Met Trp Met 20 <210> 1804 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1804 Xaa Tyr Val Glu Val Gly Tyr Tyr Phe His Ala Thr Asp Asn Glu Val 1 5 10 15 Ile Ile Tyr Ala Asn 20 <210> 1805 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1805 Xaa Tyr Ile Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp 1 5 10 15 Asn Tyr Met Trp Met 20 <210> 1806 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1806 Xaa Arg Ile Glu Leu Gly Trp His Val Leu Glu Asp Gly Arg Asp His 1 5 10 15 Gly Ile Arg Trp Ile 20 <210> 1807 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1807 Xaa Gln Val Trp Val Gly Tyr Tyr Asn Thr Ile Glu Asn Thr Glu Leu 1 5 10 15 Val Met Trp Thr Val 20 <210> 1808 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1808 Xaa Tyr Val Glu Val Gly Tyr Tyr Ser His Thr Thr Asp Asn Glu Val 1 5 10 15 Ile Ile Tyr Ala Asn 20 <210> 1809 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1809 Xaa Ser Ile Glu Val Gly Thr Tyr Asp Ser Arg Thr Glu Lys Tyr Arg 1 5 10 15 Ile Trp Phe Tyr Tyr 20 <210> 1810 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1810 Xaa Trp Ser Ile Glu Leu Tyr Ile Glu Asn Leu Asp Asp Gly Glu Glu 1 5 10 15 Val Met Val Trp Thr 20 <210> 1811 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 1811 Xaa Tyr Thr Val Glu Val Gly Trp His Thr Val Tyr Thr Gly Arg Asp 1 5 10 15 Asn Tyr Met Trp Met 20 <210> 1812 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (6)..(16) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1812 Thr Glu Asn Ala Val Cys Ile Arg Ile Thr Met Trp Ile Glu Leu Cys 1 5 10 15 Ser Glu Arg Ile 20 <210> 1813 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1813 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1814 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1814 Gly Val Ile His Tyr Glu Trp Trp Asn Asp Tyr Glu Val Ser Tyr Pro 1 5 10 15 Arg Ile Trp Gly 20 <210> 1815 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1815 Arg Ile Ile Trp Tyr Trp Gly Trp Gly Ser Val Tyr Val Glu Glu Tyr 1 5 10 15 Asp Asn His Pro 20 <210> 1816 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1816 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 1817 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1817 Gly Trp Thr Thr Met Tyr His Val Val His Met Val Glu Gly Tyr Trp 1 5 10 15 Asp Thr Asn Arg 20 <210> 1818 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1818 Arg Glu His Met Val Asn Val Gly Trp Asp Trp Thr Tyr Gly Thr Thr 1 5 10 15 Tyr Val His Met 20 <210> 1819 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1819 Gly Arg His Thr Asn Asp Ile Asn Lys Met Arg Arg Ala Val Gln Ala 1 5 10 15 Leu Phe Glu Asn 20 <210> 1820 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1820 Phe Ala Glu Asn Asp Val Asn Met His Asn Ile Gly Arg Leu Arg Gln 1 5 10 15 Thr Ala Arg Lys 20 <210> 1821 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1821 Gln Arg Thr Lys Ala Met Arg Asn Arg Leu Phe Glu His Gly Ile Asn 1 5 10 15 Asp Ala Val Asn 20 <210> 1822 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1822 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 1823 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1823 Tyr Gln Gly Ser His Asp Trp His Tyr Ser Ser Asp Tyr Val Ser Arg 1 5 10 15 Tyr Ala Val Ile 20 <210> 1824 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1824 Tyr His Ser Tyr Asp Gly Tyr Trp Ser Ile His Ala Tyr Asp Arg Val 1 5 10 15 Gln Ser Ser Val 20 <210> 1825 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1825 Tyr Val Glu Val Gly Tyr Tyr Phe His Thr Thr Asp Asn Glu Val Val 1 5 10 15 Ile Tyr Ala Asn 20 <210> 1826 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1826 Phe Gly Asn Tyr Val Asn Tyr Glu Val Ala Asp Glu Thr Val Val Thr 1 5 10 15 Ile His Tyr Tyr 20 <210> 1827 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1827 Tyr Ala Glu Tyr Thr Phe Val Glu His Val Val Asn Thr Gly Asp Tyr 1 5 10 15 Ile Asn Val Tyr 20 <210> 1828 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1828 Ser Ile Glu Val Gly Thr Tyr Asp Ser Arg Thr Glu Lys Tyr Arg Ile 1 5 10 15 Trp Phe Tyr Tyr 20 <210> 1829 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1829 Tyr Ile Lys Trp Tyr Glu Arg Thr Ser Asp Thr Val Phe Gly Arg Ile 1 5 10 15 Ser Tyr Tyr Glu 20 <210> 1830 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1830 Phe Glu Tyr Thr Ile Tyr Lys Tyr Arg Trp Thr Arg Gly Ser Asp Tyr 1 5 10 15 Val Ile Ser Glu 20 <210> 1831 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (7)..(17) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1831 Val Phe Gln Lys Glu Glu Cys Val Leu Ala Thr Glu Ser Val Trp Val 1 5 10 15 Cys Trp Gly Asn 20 <210> 1832 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (7)..(17) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1832 Gln Gly Trp Val Asn Ser Cys Glu Thr Leu Phe Ala Val Val Glu Lys 1 5 10 15 Cys Glu Trp Val 20 <210> 1833 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (7)..(17) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1833 Glu Val Trp Lys Trp Asn Cys Thr Ser Val Phe Glu Val Gly Gln Val 1 5 10 15 Cys Ala Glu Leu 20 <210> 1834 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1834 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 1835 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1835 Ala Gly Trp Val Ile Asp Gln Leu Tyr Trp Lys Gly Met Pro Trp Gly 1 5 10 15 Trp Glu Arg Glu 20 <210> 1836 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1836 Arg Ile Asp Gly Glu Tyr Leu Gln Met Trp Ala Trp Pro Trp Glu Trp 1 5 10 15 Lys Val Gly Gly 20 <210> 1837 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (8)..(18) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1837 Glu Arg Glu Asp Thr Thr Tyr Cys Val Val Val Ala Ser Gly Val Glu 1 5 10 15 Leu Cys Trp Gln 20 <210> 1838 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (8)..(18) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1838 Thr Ser Val Gly Thr Val Glu Cys Tyr Glu Trp Val Leu Asp Gln Ala 1 5 10 15 Glu Cys Val Arg 20 <210> 1839 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (8)..(18) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1839 Glu Thr Gln Thr Ser Glu Tyr Cys Gly Trp Val Ala Glu Arg Asp Val 1 5 10 15 Val Cys Leu Val 20 <210> 1840 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (7)..(17) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1840 Leu Asp Gly Gly His Trp Cys Trp Glu Ile Ser Asp Ser Val Met Leu 1 5 10 15 Cys Val Ala Val 20 <210> 1841 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (7)..(17) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1841 Leu His Val Trp Ser Asp Cys Ile Trp Leu Asp Val Gly Glu Ser Met 1 5 10 15 Cys Val Gly Ala 20 <210> 1842 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> DISULFID <222> (7)..(17) <223> Cys residues linked via disulfide bond <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1842 Val Trp Leu Met Val Leu Cys Ile Asp Gly Val Ser Asp Gly Trp His 1 5 10 15 Cys Ala Ser Glu 20 <210> 1843 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1843 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 1844 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1844 Lys Gly Gln Val Glu Ile Gly Leu Tyr Trp Val Lys Leu His Val Ile 1 5 10 15 Ser Met Thr Asn 20 <210> 1845 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1845 Gln Ile Val Ile Val Leu Glu Thr Gly His Trp Lys Ser Asn Met Tyr 1 5 10 15 Lys Gly Leu Val 20 <210> 1846 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1846 Val Glu Val Gly Trp Glu Gln Asp Gly Val Thr Val Trp Thr Val Thr 1 5 10 15 Trp Tyr His Thr 20 <210> 1847 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1847 Glu His Val Thr Val Asp Val Glu Trp Val Val Thr Gly Trp Gln Tyr 1 5 10 15 Trp Thr Gly Thr 20 <210> 1848 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1848 Gln Trp Val Trp Thr His Asp Thr Val Glu Val Glu Tyr Val Gly Gly 1 5 10 15 Thr Trp Val Thr 20 <210> 1849 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1849 Ala Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1850 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1850 Val Ala Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1851 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1851 Val Tyr Ala Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1852 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1852 Val Tyr Glu Ala Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1853 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1853 Val Tyr Glu Val Ala Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1854 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1854 Val Tyr Glu Val Gly Ala Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1855 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1855 Val Tyr Glu Val Gly Trp Ala His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1856 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1856 Val Tyr Glu Val Gly Trp Asp Ala Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1857 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1857 Val Tyr Glu Val Gly Trp Asp His Ala Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1858 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1858 Val Tyr Glu Val Gly Trp Asp His Gly Ala Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1859 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1859 Val Tyr Glu Val Gly Trp Asp His Gly Asn Ala Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1860 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1860 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Ala Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1861 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1861 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Ala Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1862 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1862 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ala Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1863 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1863 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ala Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1864 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1864 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Ala 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1865 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1865 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Ala Tyr Pro Ser 20 <210> 1866 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1866 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Ala Pro Ser 20 <210> 1867 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1867 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Ala Ser 20 <210> 1868 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1868 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ala 20 <210> 1869 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1869 Asp Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1870 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1870 Val Asp Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1871 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1871 Val Tyr Asp Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1872 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1872 Val Tyr Glu Asp Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1873 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1873 Val Tyr Glu Val Asp Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1874 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1874 Val Tyr Glu Val Gly Asp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1875 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1875 Val Tyr Glu Val Gly Trp Asp Asp Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1876 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1876 Val Tyr Glu Val Gly Trp Asp His Asp Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1877 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1877 Val Tyr Glu Val Gly Trp Asp His Gly Asp Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1878 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1878 Val Tyr Glu Val Gly Trp Asp His Gly Asn Asp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1879 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1879 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Asp Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1880 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1880 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Asp Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1881 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1881 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Asp Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1882 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1882 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Asp Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1883 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1883 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Asp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1884 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1884 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Asp Tyr Pro Ser 20 <210> 1885 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1885 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Asp Pro Ser 20 <210> 1886 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1886 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Asp Ser 20 <210> 1887 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1887 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Asp 20 <210> 1888 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1888 Gly Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1889 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1889 Val Gly Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1890 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1890 Val Tyr Gly Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1891 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1891 Val Tyr Glu Gly Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1892 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1892 Val Tyr Glu Val Gly Gly Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1893 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1893 Val Tyr Glu Val Gly Trp Gly His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1894 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1894 Val Tyr Glu Val Gly Trp Asp Gly Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1895 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1895 Val Tyr Glu Val Gly Trp Asp His Gly Gly Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1896 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1896 Val Tyr Glu Val Gly Trp Asp His Gly Asn Gly Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1897 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1897 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Gly Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1898 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1898 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Gly Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1899 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1899 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Gly Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1900 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1900 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Gly Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1901 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1901 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Gly 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1902 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1902 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Gly Tyr Pro Ser 20 <210> 1903 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1903 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Gly Pro Ser 20 <210> 1904 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1904 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Gly Ser 20 <210> 1905 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1905 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Gly 20 <210> 1906 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1906 Leu Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1907 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1907 Val Leu Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1908 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1908 Val Tyr Leu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1909 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1909 Val Tyr Glu Leu Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1910 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1910 Val Tyr Glu Val Leu Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1911 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1911 Val Tyr Glu Val Gly Leu Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1912 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1912 Val Tyr Glu Val Gly Trp Leu His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1913 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1913 Val Tyr Glu Val Gly Trp Asp Leu Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1914 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1914 Val Tyr Glu Val Gly Trp Asp His Leu Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1915 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1915 Val Tyr Glu Val Gly Trp Asp His Gly Leu Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1916 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1916 Val Tyr Glu Val Gly Trp Asp His Gly Asn Leu Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1917 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1917 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Leu Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1918 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1918 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Leu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1919 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1919 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Leu Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1920 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1920 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Leu Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1921 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1921 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Leu 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1922 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1922 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Leu Tyr Pro Ser 20 <210> 1923 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1923 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Leu Pro Ser 20 <210> 1924 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1924 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Leu Ser 20 <210> 1925 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1925 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Leu 20 <210> 1926 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1926 Lys Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1927 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1927 Val Lys Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1928 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1928 Val Tyr Lys Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1929 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1929 Val Tyr Glu Lys Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1930 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1930 Val Tyr Glu Val Lys Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1931 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1931 Val Tyr Glu Val Gly Lys Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1932 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1932 Val Tyr Glu Val Gly Trp Lys His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1933 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1933 Val Tyr Glu Val Gly Trp Asp Lys Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1934 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1934 Val Tyr Glu Val Gly Trp Asp His Lys Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1935 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1935 Val Tyr Glu Val Gly Trp Asp His Gly Lys Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1936 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1936 Val Tyr Glu Val Gly Trp Asp His Gly Asn Lys Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1937 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1937 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Lys Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1938 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1938 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Lys Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1939 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1939 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Lys Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1940 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1940 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Lys Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1941 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1941 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Lys 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1942 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1942 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Lys Tyr Pro Ser 20 <210> 1943 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1943 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Lys Pro Ser 20 <210> 1944 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1944 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Lys Ser 20 <210> 1945 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1945 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Lys 20 <210> 1946 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1946 Phe Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1947 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1947 Val Phe Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1948 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1948 Val Tyr Phe Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1949 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1949 Val Tyr Glu Phe Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1950 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1950 Val Tyr Glu Val Phe Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1951 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1951 Val Tyr Glu Val Gly Phe Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1952 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1952 Val Tyr Glu Val Gly Trp Phe His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1953 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1953 Val Tyr Glu Val Gly Trp Asp Phe Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1954 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1954 Val Tyr Glu Val Gly Trp Asp His Phe Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1955 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1955 Val Tyr Glu Val Gly Trp Asp His Gly Phe Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1956 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1956 Val Tyr Glu Val Gly Trp Asp His Gly Asn Phe Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1957 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1957 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Phe Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1958 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1958 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Phe Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1959 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1959 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Phe Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1960 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1960 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Phe Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1961 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1961 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Phe 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1962 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1962 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Phe Tyr Pro Ser 20 <210> 1963 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1963 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Phe Pro Ser 20 <210> 1964 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1964 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Phe Ser 20 <210> 1965 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1965 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Phe 20 <210> 1966 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1966 Pro Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1967 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1967 Val Pro Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1968 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1968 Val Tyr Pro Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1969 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1969 Val Tyr Glu Pro Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1970 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1970 Val Tyr Glu Val Pro Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1971 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1971 Val Tyr Glu Val Gly Pro Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1972 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1972 Val Tyr Glu Val Gly Trp Pro His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1973 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1973 Val Tyr Glu Val Gly Trp Asp Pro Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1974 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1974 Val Tyr Glu Val Gly Trp Asp His Pro Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1975 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1975 Val Tyr Glu Val Gly Trp Asp His Gly Pro Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1976 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1976 Val Tyr Glu Val Gly Trp Asp His Gly Asn Pro Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1977 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1977 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Pro Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1978 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1978 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Pro Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1979 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1979 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Pro Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1980 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1980 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Pro Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1981 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1981 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Pro 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1982 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1982 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Pro Tyr Pro Ser 20 <210> 1983 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1983 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Pro Pro Ser 20 <210> 1984 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1984 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Pro 20 <210> 1985 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1985 Ser Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1986 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1986 Val Ser Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1987 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1987 Val Tyr Ser Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1988 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1988 Val Tyr Glu Ser Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1989 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1989 Val Tyr Glu Val Ser Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1990 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1990 Val Tyr Glu Val Gly Ser Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1991 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1991 Val Tyr Glu Val Gly Trp Ser His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1992 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1992 Val Tyr Glu Val Gly Trp Asp Ser Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1993 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1993 Val Tyr Glu Val Gly Trp Asp His Ser Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1994 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1994 Val Tyr Glu Val Gly Trp Asp His Gly Ser Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1995 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1995 Val Tyr Glu Val Gly Trp Asp His Gly Asn Ser Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1996 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1996 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Ser Glu Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1997 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1997 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Ser Ile Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1998 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1998 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ser Ile Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 1999 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 1999 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ser Trp 1 5 10 15 Arg Tyr Pro Ser 20 <210> 2000 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2000 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Ser 1 5 10 15 Arg Tyr Pro Ser 20 <210> 2001 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2001 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Ser Tyr Pro Ser 20 <210> 2002 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2002 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Ser Pro Ser 20 <210> 2003 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2003 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Tyr Ser Ser 20 <210> 2004 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2004 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg <210> 2005 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2005 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile 1 5 10 <210> 2006 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 2006 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp 1 5 10 <210> 2007 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2007 Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp Arg Tyr Pro 1 5 10 15 Ser <210> 2008 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2008 Asp His Gly Asn Trp Tyr Glu Ile Ile Trp Arg Tyr Pro Ser 1 5 10 <210> 2009 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 2009 Asn Trp Tyr Glu Ile Ile Trp Arg Tyr Pro Ser 1 5 10 <210> 2010 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2010 Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp Arg 1 5 10 <210> 2011 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2011 Ala Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2012 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2012 Tyr Ala Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2013 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2013 Tyr Thr Ala Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2014 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2014 Tyr Thr Val Ala Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2015 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2015 Tyr Thr Val Glu Ala Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2016 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2016 Tyr Thr Val Glu Val Ala Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2017 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2017 Tyr Thr Val Glu Val Gly Ala His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2018 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2018 Tyr Thr Val Glu Val Gly Trp Ala Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2019 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2019 Tyr Thr Val Glu Val Gly Trp His Ala Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2020 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2020 Tyr Thr Val Glu Val Gly Trp His Thr Ala His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2021 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2021 Tyr Thr Val Glu Val Gly Trp His Thr Val Ala Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2022 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2022 Tyr Thr Val Glu Val Gly Trp His Thr Val His Ala Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2023 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2023 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Ala Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2024 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2024 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Ala Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2025 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2025 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Ala Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2026 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2026 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Ala 1 5 10 15 Tyr Met Trp Met 20 <210> 2027 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2027 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Ala Met Trp Met 20 <210> 2028 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2028 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Ala Trp Met 20 <210> 2029 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2029 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Ala Met 20 <210> 2030 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2030 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Ala 20 <210> 2031 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2031 Asp Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2032 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2032 Tyr Asp Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2033 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2033 Tyr Thr Asp Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2034 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2034 Tyr Thr Val Asp Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2035 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2035 Tyr Thr Val Glu Asp Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2036 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2036 Tyr Thr Val Glu Val Asp Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2037 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2037 Tyr Thr Val Glu Val Gly Asp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2038 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2038 Tyr Thr Val Glu Val Gly Trp Asp Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2039 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2039 Tyr Thr Val Glu Val Gly Trp His Asp Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2040 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2040 Tyr Thr Val Glu Val Gly Trp His Thr Asp His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2041 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2041 Tyr Thr Val Glu Val Gly Trp His Thr Val Asp Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2042 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2042 Tyr Thr Val Glu Val Gly Trp His Thr Val His Asp Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2043 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2043 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Asp Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2044 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2044 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Asp Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2045 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2045 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asp 1 5 10 15 Tyr Met Trp Met 20 <210> 2046 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2046 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Asp Met Trp Met 20 <210> 2047 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2047 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Asp Trp Met 20 <210> 2048 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2048 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Asp Met 20 <210> 2049 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2049 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Asp 20 <210> 2050 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2050 Gly Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2051 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2051 Tyr Gly Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2052 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2052 Tyr Thr Gly Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2053 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2053 Tyr Thr Val Gly Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2054 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2054 Tyr Thr Val Glu Gly Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2055 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2055 Tyr Thr Val Glu Val Gly Gly His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2056 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2056 Tyr Thr Val Glu Val Gly Trp Gly Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2057 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2057 Tyr Thr Val Glu Val Gly Trp His Gly Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2058 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2058 Tyr Thr Val Glu Val Gly Trp His Thr Gly His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2059 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2059 Tyr Thr Val Glu Val Gly Trp His Thr Val Gly Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2060 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2060 Tyr Thr Val Glu Val Gly Trp His Thr Val His Gly Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2061 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2061 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Gly Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2062 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2062 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Gly Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2063 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2063 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Gly 1 5 10 15 Tyr Met Trp Met 20 <210> 2064 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2064 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Gly Met Trp Met 20 <210> 2065 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2065 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Gly Trp Met 20 <210> 2066 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2066 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Gly Met 20 <210> 2067 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2067 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Gly 20 <210> 2068 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2068 Leu Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2069 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2069 Tyr Leu Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2070 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2070 Tyr Thr Leu Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2071 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2071 Tyr Thr Val Leu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2072 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2072 Tyr Thr Val Glu Leu Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2073 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2073 Tyr Thr Val Glu Val Leu Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2074 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2074 Tyr Thr Val Glu Val Gly Leu His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2075 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2075 Tyr Thr Val Glu Val Gly Trp Leu Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2076 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2076 Tyr Thr Val Glu Val Gly Trp His Leu Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2077 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2077 Tyr Thr Val Glu Val Gly Trp His Thr Leu His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2078 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2078 Tyr Thr Val Glu Val Gly Trp His Thr Val Leu Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2079 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2079 Tyr Thr Val Glu Val Gly Trp His Thr Val His Leu Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2080 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2080 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Leu Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2081 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2081 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Leu Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2082 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2082 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Leu Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2083 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2083 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Leu 1 5 10 15 Tyr Met Trp Met 20 <210> 2084 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2084 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Leu Met Trp Met 20 <210> 2085 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2085 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Leu Trp Met 20 <210> 2086 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2086 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Leu Met 20 <210> 2087 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2087 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Leu 20 <210> 2088 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2088 Lys Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2089 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2089 Tyr Lys Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2090 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2090 Tyr Thr Lys Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2091 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2091 Tyr Thr Val Lys Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2092 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2092 Tyr Thr Val Glu Lys Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2093 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2093 Tyr Thr Val Glu Val Lys Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2094 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2094 Tyr Thr Val Glu Val Gly Lys His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2095 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2095 Tyr Thr Val Glu Val Gly Trp Lys Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2096 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2096 Tyr Thr Val Glu Val Gly Trp His Lys Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2097 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2097 Tyr Thr Val Glu Val Gly Trp His Thr Lys His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2098 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2098 Tyr Thr Val Glu Val Gly Trp His Thr Val Lys Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2099 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2099 Tyr Thr Val Glu Val Gly Trp His Thr Val His Lys Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2100 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2100 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Lys Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2101 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2101 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Lys Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2102 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2102 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Lys Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2103 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2103 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Lys 1 5 10 15 Tyr Met Trp Met 20 <210> 2104 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2104 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Lys Met Trp Met 20 <210> 2105 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2105 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Lys Trp Met 20 <210> 2106 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2106 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Lys Met 20 <210> 2107 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2107 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Lys 20 <210> 2108 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2108 Phe Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2109 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2109 Tyr Phe Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2110 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2110 Tyr Thr Phe Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2111 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2111 Tyr Thr Val Phe Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2112 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2112 Tyr Thr Val Glu Phe Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2113 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2113 Tyr Thr Val Glu Val Phe Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2114 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2114 Tyr Thr Val Glu Val Gly Phe His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2115 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2115 Tyr Thr Val Glu Val Gly Trp Phe Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2116 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2116 Tyr Thr Val Glu Val Gly Trp His Phe Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2117 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2117 Tyr Thr Val Glu Val Gly Trp His Thr Phe His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2118 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2118 Tyr Thr Val Glu Val Gly Trp His Thr Val Phe Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2119 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2119 Tyr Thr Val Glu Val Gly Trp His Thr Val His Phe Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2120 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2120 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Phe Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2121 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2121 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Phe Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2122 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2122 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Phe Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2123 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2123 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Phe 1 5 10 15 Tyr Met Trp Met 20 <210> 2124 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2124 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Phe Met Trp Met 20 <210> 2125 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2125 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Phe Trp Met 20 <210> 2126 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2126 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Phe Met 20 <210> 2127 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2127 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Phe 20 <210> 2128 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2128 Pro Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2129 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2129 Tyr Pro Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2130 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2130 Tyr Thr Pro Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2131 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2131 Tyr Thr Val Pro Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2132 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2132 Tyr Thr Val Glu Pro Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2133 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2133 Tyr Thr Val Glu Val Pro Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2134 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2134 Tyr Thr Val Glu Val Gly Pro His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2135 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2135 Tyr Thr Val Glu Val Gly Trp Pro Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2136 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2136 Tyr Thr Val Glu Val Gly Trp His Pro Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2137 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2137 Tyr Thr Val Glu Val Gly Trp His Thr Pro His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2138 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2138 Tyr Thr Val Glu Val Gly Trp His Thr Val Pro Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2139 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2139 Tyr Thr Val Glu Val Gly Trp His Thr Val His Pro Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2140 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2140 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Pro Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2141 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2141 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Pro Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2142 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2142 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Pro Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2143 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2143 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Pro 1 5 10 15 Tyr Met Trp Met 20 <210> 2144 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2144 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Pro Met Trp Met 20 <210> 2145 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2145 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Pro Trp Met 20 <210> 2146 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2146 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Pro Met 20 <210> 2147 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2147 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Pro 20 <210> 2148 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2148 Ser Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2149 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2149 Tyr Ser Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2150 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2150 Tyr Thr Ser Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2151 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2151 Tyr Thr Val Ser Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2152 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2152 Tyr Thr Val Glu Ser Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2153 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2153 Tyr Thr Val Glu Val Ser Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2154 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2154 Tyr Thr Val Glu Val Gly Ser His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2155 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2155 Tyr Thr Val Glu Val Gly Trp Ser Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2156 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2156 Tyr Thr Val Glu Val Gly Trp His Ser Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2157 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2157 Tyr Thr Val Glu Val Gly Trp His Thr Ser His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2158 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2158 Tyr Thr Val Glu Val Gly Trp His Thr Val Ser Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2159 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2159 Tyr Thr Val Glu Val Gly Trp His Thr Val His Ser Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2160 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2160 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Ser Arg Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2161 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2161 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Ser Asp Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2162 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2162 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Ser Asn 1 5 10 15 Tyr Met Trp Met 20 <210> 2163 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2163 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Ser 1 5 10 15 Tyr Met Trp Met 20 <210> 2164 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2164 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Ser Met Trp Met 20 <210> 2165 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2165 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Ser Trp Met 20 <210> 2166 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2166 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Ser Met 20 <210> 2167 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2167 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr Met Trp Ser 20 <210> 2168 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2168 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn 1 5 10 15 Tyr <210> 2169 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2169 Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg 1 5 10 <210> 2170 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 2170 Tyr Thr Val Glu Val Gly Trp His Thr Val His 1 5 10 <210> 2171 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2171 Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn Tyr Met Trp 1 5 10 15 Met <210> 2172 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2172 Trp His Thr Val His Thr Gly Arg Asp Asn Tyr Met Trp Met 1 5 10 <210> 2173 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 2173 Val His Thr Gly Arg Asp Asn Tyr Met Trp Met 1 5 10 <210> 2174 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2174 Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp Asn Tyr 1 5 10 <210> 2175 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2175 Ala Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2176 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2176 His Ala Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2177 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2177 His Val Ala Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2178 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2178 His Val Gln Ala Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2179 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2179 His Val Gln Ile Ala Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2180 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2180 His Val Gln Ile Gly Ala Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2181 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2181 His Val Gln Ile Gly Trp Ala Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2182 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2182 His Val Gln Ile Gly Trp Tyr Ala Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2183 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2183 His Val Gln Ile Gly Trp Tyr Ser Ala Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2184 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2184 His Val Gln Ile Gly Trp Tyr Ser Val Ala Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2185 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2185 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ala Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2186 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2186 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Ala Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2187 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2187 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Ala His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2188 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2188 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg Ala Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2189 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2189 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Ala Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2190 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2190 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Ala Ser Ser Tyr 20 <210> 2191 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2191 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ala Ser Tyr 20 <210> 2192 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2192 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ala Tyr 20 <210> 2193 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2193 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Ala 20 <210> 2194 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2194 Asp Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2195 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2195 His Asp Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2196 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2196 His Val Asp Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2197 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2197 His Val Gln Asp Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2198 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2198 His Val Gln Ile Asp Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2199 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2199 His Val Gln Ile Gly Asp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2200 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2200 His Val Gln Ile Gly Trp Asp Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2201 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2201 His Val Gln Ile Gly Trp Tyr Asp Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2202 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2202 His Val Gln Ile Gly Trp Tyr Ser Asp Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2203 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2203 His Val Gln Ile Gly Trp Tyr Ser Val Asp Asp Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2204 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2204 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Asp His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2205 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2205 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg Asp Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2206 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2206 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Asp Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2207 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2207 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Asp 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2208 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2208 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Asp Ser Ser Tyr 20 <210> 2209 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2209 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Asp Ser Tyr 20 <210> 2210 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2210 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Asp Tyr 20 <210> 2211 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2211 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Asp 20 <210> 2212 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2212 Gly Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2213 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2213 His Gly Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2214 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2214 His Val Gly Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2215 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2215 His Val Gln Gly Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2216 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2216 His Val Gln Ile Gly Gly Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2217 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2217 His Val Gln Ile Gly Trp Gly Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2218 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2218 His Val Gln Ile Gly Trp Tyr Gly Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2219 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2219 His Val Gln Ile Gly Trp Tyr Ser Gly Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2220 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2220 His Val Gln Ile Gly Trp Tyr Ser Val Gly Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2221 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2221 His Val Gln Ile Gly Trp Tyr Ser Val Asp Gly Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2222 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2222 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Gly Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2223 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2223 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Gly His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2224 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2224 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg Gly Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2225 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2225 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Gly Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2226 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2226 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Gly 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2227 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2227 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Gly Ser Ser Tyr 20 <210> 2228 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2228 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Gly Ser Tyr 20 <210> 2229 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2229 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Gly Tyr 20 <210> 2230 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2230 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Gly 20 <210> 2231 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2231 Leu Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2232 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2232 His Leu Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2233 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2233 His Val Leu Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2234 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2234 His Val Gln Leu Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2235 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2235 His Val Gln Ile Leu Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2236 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2236 His Val Gln Ile Gly Leu Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2237 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2237 His Val Gln Ile Gly Trp Leu Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2238 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2238 His Val Gln Ile Gly Trp Tyr Leu Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2239 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2239 His Val Gln Ile Gly Trp Tyr Ser Leu Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2240 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2240 His Val Gln Ile Gly Trp Tyr Ser Val Leu Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2241 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2241 His Val Gln Ile Gly Trp Tyr Ser Val Asp Leu Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2242 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2242 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Leu Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2243 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2243 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Leu His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2244 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2244 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg Leu Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2245 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2245 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Leu Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2246 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2246 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Leu 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2247 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2247 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Leu Ser Ser Tyr 20 <210> 2248 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2248 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Leu Ser Tyr 20 <210> 2249 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2249 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Leu Tyr 20 <210> 2250 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2250 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Leu 20 <210> 2251 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2251 Lys Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2252 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2252 His Lys Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2253 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2253 His Val Lys Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2254 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2254 His Val Gln Lys Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2255 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2255 His Val Gln Ile Lys Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2256 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2256 His Val Gln Ile Gly Lys Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2257 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2257 His Val Gln Ile Gly Trp Lys Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2258 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2258 His Val Gln Ile Gly Trp Tyr Lys Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2259 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2259 His Val Gln Ile Gly Trp Tyr Ser Lys Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2260 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2260 His Val Gln Ile Gly Trp Tyr Ser Val Lys Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2261 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2261 His Val Gln Ile Gly Trp Tyr Ser Val Asp Lys Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2262 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2262 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Lys Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2263 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2263 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Lys His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2264 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2264 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg Lys Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2265 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2265 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Lys Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2266 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2266 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Lys 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2267 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2267 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Lys Ser Ser Tyr 20 <210> 2268 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2268 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Lys Ser Tyr 20 <210> 2269 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2269 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Lys Tyr 20 <210> 2270 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2270 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Lys 20 <210> 2271 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2271 Phe Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2272 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2272 His Phe Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2273 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2273 His Val Phe Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2274 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2274 His Val Gln Phe Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2275 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2275 His Val Gln Ile Phe Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2276 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2276 His Val Gln Ile Gly Phe Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2277 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2277 His Val Gln Ile Gly Trp Phe Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2278 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2278 His Val Gln Ile Gly Trp Tyr Phe Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2279 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2279 His Val Gln Ile Gly Trp Tyr Ser Phe Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2280 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2280 His Val Gln Ile Gly Trp Tyr Ser Val Phe Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2281 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2281 His Val Gln Ile Gly Trp Tyr Ser Val Asp Phe Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2282 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2282 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Phe Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2283 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2283 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Phe His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2284 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2284 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg Phe Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2285 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2285 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Phe Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2286 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2286 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Phe 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2287 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2287 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Phe Ser Ser Tyr 20 <210> 2288 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2288 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Phe Ser Tyr 20 <210> 2289 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2289 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Phe Tyr 20 <210> 2290 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2290 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Phe 20 <210> 2291 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2291 Pro Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2292 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2292 His Pro Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2293 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2293 His Val Pro Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2294 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2294 His Val Gln Pro Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2295 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2295 His Val Gln Ile Pro Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2296 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2296 His Val Gln Ile Gly Pro Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2297 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2297 His Val Gln Ile Gly Trp Pro Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2298 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2298 His Val Gln Ile Gly Trp Tyr Pro Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2299 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2299 His Val Gln Ile Gly Trp Tyr Ser Pro Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2300 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2300 His Val Gln Ile Gly Trp Tyr Ser Val Pro Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2301 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2301 His Val Gln Ile Gly Trp Tyr Ser Val Asp Pro Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2302 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2302 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Pro Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2303 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2303 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Pro His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2304 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2304 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg Pro Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2305 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2305 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Pro Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2306 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2306 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Pro 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2307 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2307 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Pro Ser Ser Tyr 20 <210> 2308 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2308 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Pro Ser Tyr 20 <210> 2309 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2309 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Pro Tyr 20 <210> 2310 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2310 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Pro 20 <210> 2311 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2311 Ser Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2312 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2312 His Ser Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2313 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2313 His Val Ser Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2314 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2314 His Val Gln Ser Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2315 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2315 His Val Gln Ile Ser Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2316 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2316 His Val Gln Ile Gly Ser Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2317 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2317 His Val Gln Ile Gly Trp Ser Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2318 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2318 His Val Gln Ile Gly Trp Tyr Ser Ser Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2319 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2319 His Val Gln Ile Gly Trp Tyr Ser Val Ser Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2320 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2320 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Ser Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2321 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2321 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Ser His Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2322 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2322 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg Ser Tyr Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2323 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2323 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Ser Ala 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2324 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2324 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ser 1 5 10 15 Tyr Ser Ser Tyr 20 <210> 2325 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2325 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Ser Ser Ser Tyr 20 <210> 2326 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2326 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr Ser Ser Ser 20 <210> 2327 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2327 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala 1 5 10 15 Tyr <210> 2328 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2328 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His 1 5 10 <210> 2329 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 2329 His Val Gln Ile Gly Trp Tyr Ser Val Asp Ser 1 5 10 <210> 2330 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2330 Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala Tyr Ser Ser 1 5 10 15 Tyr <210> 2331 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2331 Tyr Ser Val Asp Ser Asp Arg His Tyr Ala Tyr Ser Ser Tyr 1 5 10 <210> 2332 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 2332 Asp Ser Asp Arg His Tyr Ala Tyr Ser Ser Tyr 1 5 10 <210> 2333 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2333 Ile Gly Trp Tyr Ser Val Asp Ser Asp Arg His Tyr Ala Tyr 1 5 10 <210> 2334 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2334 Ala Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2335 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2335 Asp Ala Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2336 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2336 Asp Gln Ala Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2337 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2337 Asp Gln Val Ala Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2338 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2338 Asp Gln Val Trp Ala Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2339 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2339 Asp Gln Val Trp Trp Ala Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2340 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2340 Asp Gln Val Trp Trp Trp Ala Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2341 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2341 Asp Gln Val Trp Trp Trp Gly Ala Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2342 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2342 Asp Gln Val Trp Trp Trp Gly Pro Ala Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2343 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2343 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Ala Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2344 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2344 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Ala Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2345 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2345 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Ala Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2346 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2346 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Ala Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2347 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2347 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ala Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2348 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2348 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Ala 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2349 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2349 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Ala Gly Trp Glu 20 <210> 2350 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2350 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Ala Trp Glu 20 <210> 2351 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2351 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Ala Glu 20 <210> 2352 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2352 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Ala 20 <210> 2353 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2353 Asp Asp Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2354 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2354 Asp Gln Asp Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2355 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2355 Asp Gln Val Asp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2356 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2356 Asp Gln Val Trp Asp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2357 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2357 Asp Gln Val Trp Trp Asp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2358 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2358 Asp Gln Val Trp Trp Trp Asp Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2359 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2359 Asp Gln Val Trp Trp Trp Gly Asp Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2360 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2360 Asp Gln Val Trp Trp Trp Gly Pro Asp Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2361 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2361 Asp Gln Val Trp Trp Trp Gly Pro Lys Asp Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2362 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2362 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Asp Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2363 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2363 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Asp Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2364 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2364 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Asp Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2365 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2365 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Asp Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2366 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2366 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Asp Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2367 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2367 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Asp 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2368 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2368 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Asp Gly Trp Glu 20 <210> 2369 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2369 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Asp Trp Glu 20 <210> 2370 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2370 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Asp Glu 20 <210> 2371 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2371 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Asp 20 <210> 2372 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2372 Gly Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2373 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2373 Asp Gly Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2374 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2374 Asp Gln Gly Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2375 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2375 Asp Gln Val Gly Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2376 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2376 Asp Gln Val Trp Gly Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2377 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2377 Asp Gln Val Trp Trp Gly Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2378 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2378 Asp Gln Val Trp Trp Trp Gly Gly Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2379 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2379 Asp Gln Val Trp Trp Trp Gly Pro Gly Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2380 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2380 Asp Gln Val Trp Trp Trp Gly Pro Lys Gly Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2381 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2381 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Gly Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2382 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2382 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Gly Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2383 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2383 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Gly Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2384 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2384 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Gly Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2385 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2385 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Gly 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2386 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2386 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Gly Gly Trp Glu 20 <210> 2387 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2387 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Gly Glu 20 <210> 2388 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2388 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Gly 20 <210> 2389 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2389 Leu Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2390 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2390 Asp Leu Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2391 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2391 Asp Gln Leu Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2392 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2392 Asp Gln Val Leu Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2393 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2393 Asp Gln Val Trp Leu Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2394 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2394 Asp Gln Val Trp Trp Leu Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2395 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2395 Asp Gln Val Trp Trp Trp Leu Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2396 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2396 Asp Gln Val Trp Trp Trp Gly Leu Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2397 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2397 Asp Gln Val Trp Trp Trp Gly Pro Leu Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2398 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2398 Asp Gln Val Trp Trp Trp Gly Pro Lys Leu Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2399 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2399 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Leu Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2400 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2400 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Leu Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2401 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2401 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Leu Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2402 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2402 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Leu Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2403 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2403 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Leu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2404 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2404 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Leu Gly Trp Glu 20 <210> 2405 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2405 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Leu Trp Glu 20 <210> 2406 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2406 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Leu Glu 20 <210> 2407 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2407 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Leu 20 <210> 2408 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2408 Lys Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2409 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2409 Asp Lys Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2410 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2410 Asp Gln Lys Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2411 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2411 Asp Gln Val Lys Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2412 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2412 Asp Gln Val Trp Lys Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2413 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2413 Asp Gln Val Trp Trp Lys Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2414 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2414 Asp Gln Val Trp Trp Trp Lys Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2415 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2415 Asp Gln Val Trp Trp Trp Gly Lys Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2416 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2416 Asp Gln Val Trp Trp Trp Gly Pro Lys Lys Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2417 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2417 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Lys Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2418 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2418 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Lys Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2419 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2419 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Lys Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2420 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2420 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Lys Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2421 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2421 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Lys Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2422 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2422 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Lys 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2423 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2423 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Lys Gly Trp Glu 20 <210> 2424 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2424 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Lys Trp Glu 20 <210> 2425 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2425 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Lys Glu 20 <210> 2426 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2426 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Lys 20 <210> 2427 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2427 Phe Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2428 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2428 Asp Phe Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2429 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2429 Asp Gln Phe Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2430 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2430 Asp Gln Val Phe Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2431 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2431 Asp Gln Val Trp Phe Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2432 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2432 Asp Gln Val Trp Trp Phe Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2433 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2433 Asp Gln Val Trp Trp Trp Phe Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2434 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2434 Asp Gln Val Trp Trp Trp Gly Phe Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2435 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2435 Asp Gln Val Trp Trp Trp Gly Pro Phe Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2436 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2436 Asp Gln Val Trp Trp Trp Gly Pro Lys Phe Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2437 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2437 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Phe Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2438 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2438 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Phe Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2439 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2439 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Phe Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2440 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2440 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Phe Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2441 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2441 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Phe Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2442 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2442 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Phe 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2443 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2443 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Phe Gly Trp Glu 20 <210> 2444 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2444 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Phe Trp Glu 20 <210> 2445 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2445 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Phe Glu 20 <210> 2446 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2446 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Phe 20 <210> 2447 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2447 Pro Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2448 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2448 Asp Pro Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2449 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2449 Asp Gln Pro Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2450 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2450 Asp Gln Val Pro Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2451 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2451 Asp Gln Val Trp Pro Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2452 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2452 Asp Gln Val Trp Trp Pro Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2453 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2453 Asp Gln Val Trp Trp Trp Pro Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2454 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2454 Asp Gln Val Trp Trp Trp Gly Pro Pro Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2455 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2455 Asp Gln Val Trp Trp Trp Gly Pro Lys Pro Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2456 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2456 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Pro Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2457 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2457 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Pro Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2458 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2458 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Pro Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2459 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2459 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Pro Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2460 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2460 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Pro Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2461 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2461 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Pro 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2462 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2462 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Pro Gly Trp Glu 20 <210> 2463 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2463 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Pro Trp Glu 20 <210> 2464 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2464 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Pro Glu 20 <210> 2465 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2465 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Pro 20 <210> 2466 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2466 Ser Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2467 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2467 Asp Ser Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2468 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2468 Asp Gln Ser Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2469 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2469 Asp Gln Val Ser Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2470 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2470 Asp Gln Val Trp Ser Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2471 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2471 Asp Gln Val Trp Trp Ser Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2472 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2472 Asp Gln Val Trp Trp Trp Ser Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2473 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2473 Asp Gln Val Trp Trp Trp Gly Ser Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2474 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2474 Asp Gln Val Trp Trp Trp Gly Pro Ser Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2475 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2475 Asp Gln Val Trp Trp Trp Gly Pro Lys Ser Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2476 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2476 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Ser Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2477 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2477 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Ser Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2478 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2478 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Ser Leu Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2479 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2479 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Ser Ile Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2480 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2480 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ser Glu 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2481 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2481 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Ser 1 5 10 15 Tyr Gly Trp Glu 20 <210> 2482 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2482 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Ser Gly Trp Glu 20 <210> 2483 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2483 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Ser Trp Glu 20 <210> 2484 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2484 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Ser Glu 20 <210> 2485 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2485 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr Gly Trp Ser 20 <210> 2486 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2486 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu 1 5 10 15 Tyr <210> 2487 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2487 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu 1 5 10 <210> 2488 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 2488 Asp Gln Val Trp Trp Trp Gly Pro Lys Ala Arg 1 5 10 <210> 2489 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2489 Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu Tyr Gly Trp 1 5 10 15 Glu <210> 2490 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2490 Gly Pro Lys Ala Arg Met Gly Leu Ile Glu Tyr Gly Trp Glu 1 5 10 <210> 2491 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 2491 Ala Arg Met Gly Leu Ile Glu Tyr Gly Trp Glu 1 5 10 <210> 2492 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2492 Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu Tyr 1 5 10 <210> 2493 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2493 Ala Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2494 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2494 Ile Ala Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2495 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2495 Ile Glu Ala Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2496 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2496 Ile Glu Val Ala Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2497 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2497 Ile Glu Val Gly Ala Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2498 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2498 Ile Glu Val Gly Trp Ala Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2499 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2499 Ile Glu Val Gly Trp Tyr Ala Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2500 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2500 Ile Glu Val Gly Trp Tyr Asn Ala Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2501 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2501 Ile Glu Val Gly Trp Tyr Asn Val Ala Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2502 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2502 Ile Glu Val Gly Trp Tyr Asn Val Val Ala Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2503 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2503 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Ala Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2504 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2504 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Ala His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2505 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2505 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys Ala Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2506 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2506 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ala Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2507 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2507 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Ala Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2508 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2508 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Ala 1 5 10 15 Gly Met Leu Ile 20 <210> 2509 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2509 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Ala Met Leu Ile 20 <210> 2510 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2510 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Ala Leu Ile 20 <210> 2511 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2511 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Ala Ile 20 <210> 2512 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2512 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ala 20 <210> 2513 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2513 Asp Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2514 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2514 Ile Asp Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2515 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2515 Ile Glu Asp Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2516 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2516 Ile Glu Val Asp Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2517 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2517 Ile Glu Val Gly Asp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2518 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2518 Ile Glu Val Gly Trp Asp Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2519 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2519 Ile Glu Val Gly Trp Tyr Asp Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2520 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2520 Ile Glu Val Gly Trp Tyr Asn Asp Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2521 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2521 Ile Glu Val Gly Trp Tyr Asn Val Asp Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2522 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2522 Ile Glu Val Gly Trp Tyr Asn Val Val Asp Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2523 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2523 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Asp Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2524 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2524 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Asp His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2525 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2525 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys Asp Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2526 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2526 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Asp Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2527 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2527 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Asp Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2528 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2528 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Asp 1 5 10 15 Gly Met Leu Ile 20 <210> 2529 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2529 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Asp Met Leu Ile 20 <210> 2530 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2530 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Asp Leu Ile 20 <210> 2531 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2531 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Asp Ile 20 <210> 2532 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2532 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Asp 20 <210> 2533 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2533 Gly Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2534 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2534 Ile Gly Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2535 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2535 Ile Glu Gly Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2536 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2536 Ile Glu Val Gly Gly Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2537 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2537 Ile Glu Val Gly Trp Gly Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2538 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2538 Ile Glu Val Gly Trp Tyr Gly Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2539 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2539 Ile Glu Val Gly Trp Tyr Asn Gly Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2540 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2540 Ile Glu Val Gly Trp Tyr Asn Val Gly Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2541 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2541 Ile Glu Val Gly Trp Tyr Asn Val Val Gly Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2542 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2542 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gly Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2543 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2543 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Gly His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2544 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2544 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys Gly Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2545 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2545 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Gly Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2546 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2546 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Gly Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2547 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2547 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Gly 1 5 10 15 Gly Met Leu Ile 20 <210> 2548 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2548 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Gly Leu Ile 20 <210> 2549 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2549 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Gly Ile 20 <210> 2550 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2550 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Gly 20 <210> 2551 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2551 Leu Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2552 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2552 Ile Leu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2553 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2553 Ile Glu Leu Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2554 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2554 Ile Glu Val Leu Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2555 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2555 Ile Glu Val Gly Leu Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2556 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2556 Ile Glu Val Gly Trp Leu Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2557 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2557 Ile Glu Val Gly Trp Tyr Leu Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2558 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2558 Ile Glu Val Gly Trp Tyr Asn Leu Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2559 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2559 Ile Glu Val Gly Trp Tyr Asn Val Leu Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2560 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2560 Ile Glu Val Gly Trp Tyr Asn Val Val Leu Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2561 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2561 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Leu Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2562 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2562 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Leu His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2563 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2563 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys Leu Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2564 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2564 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Leu Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2565 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2565 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Leu Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2566 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2566 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Leu Met Leu Ile 20 <210> 2567 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2567 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Leu Leu Ile 20 <210> 2568 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2568 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Leu 20 <210> 2569 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2569 Lys Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2570 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2570 Ile Lys Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2571 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2571 Ile Glu Lys Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2572 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2572 Ile Glu Val Lys Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2573 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2573 Ile Glu Val Gly Lys Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2574 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2574 Ile Glu Val Gly Trp Lys Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2575 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2575 Ile Glu Val Gly Trp Tyr Lys Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2576 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2576 Ile Glu Val Gly Trp Tyr Asn Lys Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2577 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2577 Ile Glu Val Gly Trp Tyr Asn Val Lys Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2578 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2578 Ile Glu Val Gly Trp Tyr Asn Val Val Lys Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2579 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2579 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Lys Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2580 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2580 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys Lys Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2581 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2581 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Lys Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2582 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2582 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Lys 1 5 10 15 Gly Met Leu Ile 20 <210> 2583 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2583 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Lys Met Leu Ile 20 <210> 2584 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2584 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Lys Leu Ile 20 <210> 2585 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2585 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Lys Ile 20 <210> 2586 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2586 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Lys 20 <210> 2587 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2587 Phe Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2588 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2588 Ile Phe Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2589 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2589 Ile Glu Phe Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2590 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2590 Ile Glu Val Phe Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2591 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2591 Ile Glu Val Gly Phe Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2592 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2592 Ile Glu Val Gly Trp Phe Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2593 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2593 Ile Glu Val Gly Trp Tyr Phe Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2594 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2594 Ile Glu Val Gly Trp Tyr Asn Phe Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2595 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2595 Ile Glu Val Gly Trp Tyr Asn Val Phe Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2596 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2596 Ile Glu Val Gly Trp Tyr Asn Val Val Phe Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2597 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2597 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Phe Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2598 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2598 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Phe His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2599 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2599 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys Phe Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2600 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2600 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Phe Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2601 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2601 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Phe Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2602 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2602 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Phe 1 5 10 15 Gly Met Leu Ile 20 <210> 2603 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2603 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Phe Met Leu Ile 20 <210> 2604 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2604 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Phe Leu Ile 20 <210> 2605 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2605 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Phe Ile 20 <210> 2606 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2606 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Phe 20 <210> 2607 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2607 Pro Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2608 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2608 Ile Pro Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2609 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2609 Ile Glu Pro Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2610 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2610 Ile Glu Val Pro Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2611 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2611 Ile Glu Val Gly Pro Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2612 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2612 Ile Glu Val Gly Trp Pro Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2613 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2613 Ile Glu Val Gly Trp Tyr Pro Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2614 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2614 Ile Glu Val Gly Trp Tyr Asn Pro Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2615 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2615 Ile Glu Val Gly Trp Tyr Asn Val Pro Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2616 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2616 Ile Glu Val Gly Trp Tyr Asn Val Val Pro Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2617 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2617 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Pro Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2618 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2618 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Pro His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2619 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2619 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys Pro Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2620 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2620 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Pro Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2621 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2621 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Pro Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2622 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2622 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Pro 1 5 10 15 Gly Met Leu Ile 20 <210> 2623 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2623 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Pro Met Leu Ile 20 <210> 2624 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2624 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Pro Leu Ile 20 <210> 2625 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2625 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Pro Ile 20 <210> 2626 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2626 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Pro 20 <210> 2627 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2627 Ser Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2628 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2628 Ile Ser Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2629 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2629 Ile Glu Ser Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2630 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2630 Ile Glu Val Ser Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2631 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2631 Ile Glu Val Gly Ser Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2632 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2632 Ile Glu Val Gly Trp Ser Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2633 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2633 Ile Glu Val Gly Trp Tyr Ser Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2634 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2634 Ile Glu Val Gly Trp Tyr Asn Ser Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2635 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2635 Ile Glu Val Gly Trp Tyr Asn Val Ser Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2636 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2636 Ile Glu Val Gly Trp Tyr Asn Val Val Ser Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2637 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2637 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Ser Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2638 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2638 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Ser His Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2639 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2639 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys Ser Ser Lys Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2640 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2640 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Ser Leu 1 5 10 15 Gly Met Leu Ile 20 <210> 2641 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2641 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Ser 1 5 10 15 Gly Met Leu Ile 20 <210> 2642 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2642 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Ser Met Leu Ile 20 <210> 2643 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2643 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Ser Leu Ile 20 <210> 2644 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2644 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Ser Ile 20 <210> 2645 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2645 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly Met Leu Ser 20 <210> 2646 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2646 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu 1 5 10 15 Gly <210> 2647 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2647 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser 1 5 10 <210> 2648 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 2648 Ile Glu Val Gly Trp Tyr Asn Val Val Thr Gln 1 5 10 <210> 2649 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2649 Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu Gly Met Leu 1 5 10 15 Ile <210> 2650 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2650 Asn Val Val Thr Gln Lys His Ser Lys Leu Gly Met Leu Ile 1 5 10 <210> 2651 <211> 11 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (11)..(11) <223> C-terminal amidation <400> 2651 Thr Gln Lys His Ser Lys Leu Gly Met Leu Ile 1 5 10 <210> 2652 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2652 Gly Trp Tyr Asn Val Val Thr Gln Lys His Ser Lys Leu Gly 1 5 10 <210> 2653 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2653 Xaa Lys Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val 1 5 10 15 Gly Trp Glu Phe Val 20 <210> 2654 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2654 Xaa His Lys Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val 1 5 10 15 Gly Trp Glu Phe Val 20 <210> 2655 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2655 Xaa His Ala Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val 1 5 10 15 Gly Trp Glu Phe Val 20 <210> 2656 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2656 Xaa His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val 1 5 10 15 Gly Trp Glu Phe Val 20 <210> 2657 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2657 Xaa His Leu Tyr Leu Trp Gln Ser Trp Pro Ser Pro Trp Val Glu Val 1 5 10 15 Gly Trp Glu Phe Val 20 <210> 2658 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2658 Xaa His Leu Tyr Leu Trp Gln Arg Ala Pro Ser Pro Trp Val Glu Val 1 5 10 15 Gly Trp Glu Phe Val 20 <210> 2659 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2659 Xaa His Leu Tyr Leu Trp Gln Arg Phe Pro Ser Pro Trp Val Glu Val 1 5 10 15 Gly Trp Glu Phe Val 20 <210> 2660 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2660 Xaa His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Phe Val Glu Val 1 5 10 15 Gly Trp Glu Phe Val 20 <210> 2661 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2661 Xaa His Leu Tyr Leu Trp Gln Arg Trp Pro Ser Pro Gly Val Glu Val 1 5 10 15 Gly Trp Glu Phe Val 20 <210> 2662 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2662 Lys Lys Tyr Leu Trp Gln Ala Ala Pro Ser Pro Gly Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2663 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2663 Xaa Lys Lys Tyr Leu Trp Gln Ala Ala Pro Ser Pro Gly Val Glu Val 1 5 10 15 Gly Trp Glu Phe Val 20 <210> 2664 <211> 28 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (28)..(28) <223> C-terminal amidation <400> 2664 Ile Pro Asp Gln Cys Ser Pro Leu Pro Cys Asn Glu Asp Gly Tyr Met 1 5 10 15 Ser Cys Lys Asp Gly Lys Ala Ser Phe Thr Cys Thr 20 25 <210> 2665 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2665 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Asp Glu Ile Ile Trp 1 5 10 15 Arg <210> 2666 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2666 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Ser Glu Ile Ile Trp 1 5 10 15 Arg <210> 2667 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2667 Val Tyr Glu Val Gly Trp Asp His Gly Asp Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg <210> 2668 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2668 Val Gly Trp Asp His Gly Asn Trp Asp Glu Ile Ile Trp Arg 1 5 10 <210> 2669 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2669 Val Gly Trp Asp His Gly Asn Trp Ser Glu Ile Ile Trp Arg 1 5 10 <210> 2670 <211> 14 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (14)..(14) <223> C-terminal amidation <400> 2670 Val Gly Trp Asp His Gly Asp Trp Tyr Glu Ile Ile Trp Arg 1 5 10 <210> 2671 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2671 Trp Trp Trp Gly Pro Lys Ala Pro Met Gly Leu Ile Glu Tyr Gly Trp 1 5 10 15 Glu <210> 2672 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2672 Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Glu Tyr Gly Trp 1 5 10 15 Leu <210> 2673 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (17)..(17) <223> C-terminal amidation <400> 2673 Trp Trp Trp Gly Pro Lys Ala Arg Met Gly Leu Ile Ser Tyr Gly Trp 1 5 10 15 Glu <210> 2674 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2674 Gly Phe Val Trp Glu Asp Leu Trp Gly Thr Val Glu Ile Trp Ile Trp 1 5 10 15 Thr Lys Lys Thr 20 <210> 2675 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2675 Xaa Trp Lys Ile Ile Val Gly Trp Glu Leu Phe Asp Thr Gly Glu Thr 1 5 10 15 Leu Trp Trp Lys Val 20 <210> 2676 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2676 Xaa Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Asp Glu Ile Ile 1 5 10 15 Trp Arg Tyr Pro Ser 20 <210> 2677 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2677 Xaa Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile 1 5 10 15 Trp Arg Asp Pro Ser 20 <210> 2678 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2678 Xaa Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp 1 5 10 15 Asn Tyr Phe Trp Met 20 <210> 2679 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2679 Xaa Tyr Thr Val Glu Val Gly Trp His Thr Val His Thr Gly Arg Asp 1 5 10 15 Asn Pro Met Trp Met 20 <210> 2680 <211> 18 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (18)..(18) <223> C-terminal amidation <400> 2680 Xaa Val Tyr Glu Val Gly Trp Asp His Gly Asp Trp Tyr Glu Ile Ile 1 5 10 15 Trp Arg <210> 2681 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2681 Xaa His Lys Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val 1 5 10 15 Gly Trp Glu Phe Val 20 <210> 2682 <211> 31 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (31)..(31) <223> C-terminal amidation <400> 2682 His Lys Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp Arg Asp Pro Ser 20 25 30 <210> 2683 <211> 32 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (32)..(32) <223> C-terminal amidation <400> 2683 Xaa His Lys Tyr Leu Trp Gln Arg Trp Pro Ser Pro Trp Val Glu Val 1 5 10 15 Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp Arg Asp Pro Ser 20 25 30 <210> 2684 <211> 29 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (29)..(29) <223> C-terminal amidation <400> 2684 His Lys Tyr Leu Trp Gln Arg Trp Pro Ser Pro Leu Val Ser Ala Gly 1 5 10 15 Trp Tyr Asp Tyr Asn Phe Asp His Tyr Arg Glu Phe Thr 20 25 <210> 2685 <211> 30 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (30)..(30) <223> C-terminal amidation <400> 2685 Xaa His Lys Tyr Leu Trp Gln Arg Trp Pro Ser Pro Leu Val Ser Ala 1 5 10 15 Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr Arg Glu Phe Thr 20 25 30 <210> 2686 <211> 29 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (29)..(29) <223> C-terminal amidation <400> 2686 His Lys Tyr Leu Trp Gln Arg Trp Pro Ser Pro Leu Val Glu Val Gly 1 5 10 15 Trp Tyr Asp Tyr Asn Phe Asp His Tyr Arg Glu Phe Thr 20 25 <210> 2687 <211> 30 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (30)..(30) <223> C-terminal amidation <400> 2687 Xaa His Lys Tyr Leu Trp Gln Arg Trp Pro Ser Pro Leu Val Glu Val 1 5 10 15 Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr Arg Glu Phe Thr 20 25 30 <210> 2688 <211> 31 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (31)..(31) <223> C-terminal amidation <400> 2688 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp Arg Asp Pro Ser 20 25 30 <210> 2689 <211> 32 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (32)..(32) <223> C-terminal amidation <400> 2689 Xaa His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val 1 5 10 15 Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp Arg Asp Pro Ser 20 25 30 <210> 2690 <211> 29 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (29)..(29) <223> C-terminal amidation <400> 2690 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Leu Val Ser Ala Gly 1 5 10 15 Trp Tyr Asp Tyr Asn Phe Asp His Tyr Arg Glu Phe Thr 20 25 <210> 2691 <211> 30 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (30)..(30) <223> C-terminal amidation <400> 2691 Xaa His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Leu Val Ser Ala 1 5 10 15 Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr Arg Glu Phe Thr 20 25 30 <210> 2692 <211> 29 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (29)..(29) <223> C-terminal amidation <400> 2692 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Leu Val Glu Val Gly 1 5 10 15 Trp Tyr Asp Tyr Asn Phe Asp His Tyr Arg Glu Phe Thr 20 25 <210> 2693 <211> 30 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (30)..(30) <223> C-terminal amidation <400> 2693 Xaa His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Leu Val Glu Val 1 5 10 15 Gly Trp Tyr Asp Tyr Asn Phe Asp His Tyr Arg Glu Phe Thr 20 25 30 <210> 2694 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2694 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Asp Pro Ser Cys 20 <210> 2695 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2695 Cys Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile 1 5 10 15 Trp Arg Asp Pro Ser 20 <210> 2696 <211> 23 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2696 Asn Cys Ser Leu Asp Asn Gly Gly Cys Thr His Tyr Cys Leu Glu Glu 1 5 10 15 Val Gly Trp Arg Arg Cys Ser 20 <210> 2697 <211> 24 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2697 Xaa Asn Cys Ser Leu Asp Asn Gly Gly Cys Thr His Tyr Cys Leu Glu 1 5 10 15 Glu Val Gly Trp Arg Arg Cys Ser 20 <210> 2698 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2698 Gly Cys Thr His Tyr Ser Leu Glu Glu Val Gly Trp Arg Arg Cys Ser 1 5 10 15 <210> 2699 <211> 17 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal biotinyl <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is (13-Amino-4,7,10-trioxa-tridecyl)-succinamic acid (ttds) <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2699 Xaa Gly Cys Thr His Tyr Ser Leu Glu Glu Val Gly Trp Arg Arg Cys 1 5 10 15 Ser <210> 2700 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2700 Glu Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2701 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2701 His Glu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2702 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2702 His Leu Glu Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2703 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2703 His Leu Tyr Glu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2704 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2704 His Leu Tyr Leu Glu Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2705 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2705 His Leu Tyr Leu Trp Glu Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2706 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2706 His Leu Tyr Leu Trp Gln Glu Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2707 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2707 His Leu Tyr Leu Trp Gln Ala Glu Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2708 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2708 His Leu Tyr Leu Trp Gln Ala Trp Glu Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2709 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2709 His Leu Tyr Leu Trp Gln Ala Trp Pro Glu Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2710 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2710 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Glu Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2711 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2711 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Glu Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2712 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2712 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Glu Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2713 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2713 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Glu Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2714 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2714 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Glu 1 5 10 15 Trp Glu Phe Val 20 <210> 2715 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2715 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Glu Glu Phe Val 20 <210> 2716 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2716 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Glu Val 20 <210> 2717 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2717 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Glu 20 <210> 2718 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2718 His His Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2719 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2719 His Leu His Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2720 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2720 His Leu Tyr His Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2721 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2721 His Leu Tyr Leu His Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2722 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2722 His Leu Tyr Leu Trp His Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2723 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2723 His Leu Tyr Leu Trp Gln His Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2724 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2724 His Leu Tyr Leu Trp Gln Ala His Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2725 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2725 His Leu Tyr Leu Trp Gln Ala Trp His Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2726 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2726 His Leu Tyr Leu Trp Gln Ala Trp Pro His Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2727 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2727 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser His Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2728 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2728 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro His Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2729 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2729 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp His Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2730 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2730 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val His Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2731 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2731 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu His Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2732 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2732 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val His 1 5 10 15 Trp Glu Phe Val 20 <210> 2733 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2733 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 His Glu Phe Val 20 <210> 2734 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2734 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp His Phe Val 20 <210> 2735 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2735 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu His Val 20 <210> 2736 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2736 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe His 20 <210> 2737 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2737 Ile Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2738 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2738 His Ile Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2739 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2739 His Leu Ile Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2740 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2740 His Leu Tyr Ile Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2741 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2741 His Leu Tyr Leu Ile Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2742 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2742 His Leu Tyr Leu Trp Ile Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2743 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2743 His Leu Tyr Leu Trp Gln Ile Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2744 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2744 His Leu Tyr Leu Trp Gln Ala Ile Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2745 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2745 His Leu Tyr Leu Trp Gln Ala Trp Ile Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2746 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2746 His Leu Tyr Leu Trp Gln Ala Trp Pro Ile Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2747 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2747 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Ile Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2748 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2748 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Ile Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2749 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2749 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Ile Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2750 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2750 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Ile Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2751 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2751 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Ile Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2752 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2752 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Ile 1 5 10 15 Trp Glu Phe Val 20 <210> 2753 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2753 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Ile Glu Phe Val 20 <210> 2754 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2754 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Ile Phe Val 20 <210> 2755 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2755 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Ile Val 20 <210> 2756 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2756 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Ile 20 <210> 2757 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2757 Met Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2758 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2758 His Met Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2759 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2759 His Leu Met Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2760 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2760 His Leu Tyr Met Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2761 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2761 His Leu Tyr Leu Met Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2762 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2762 His Leu Tyr Leu Trp Met Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2763 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2763 His Leu Tyr Leu Trp Gln Met Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2764 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2764 His Leu Tyr Leu Trp Gln Ala Met Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2765 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2765 His Leu Tyr Leu Trp Gln Ala Trp Met Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2766 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2766 His Leu Tyr Leu Trp Gln Ala Trp Pro Met Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2767 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2767 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Met Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2768 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2768 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Met Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2769 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2769 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Met Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2770 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2770 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Met Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2771 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2771 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Met Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2772 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2772 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Met 1 5 10 15 Trp Glu Phe Val 20 <210> 2773 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2773 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Met Glu Phe Val 20 <210> 2774 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2774 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Met Phe Val 20 <210> 2775 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2775 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Met Val 20 <210> 2776 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2776 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Met 20 <210> 2777 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2777 Asn Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2778 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2778 His Asn Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2779 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2779 His Leu Asn Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2780 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2780 His Leu Tyr Asn Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2781 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2781 His Leu Tyr Leu Asn Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2782 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2782 His Leu Tyr Leu Trp Asn Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2783 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2783 His Leu Tyr Leu Trp Gln Asn Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2784 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2784 His Leu Tyr Leu Trp Gln Ala Asn Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2785 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2785 His Leu Tyr Leu Trp Gln Ala Trp Asn Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2786 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2786 His Leu Tyr Leu Trp Gln Ala Trp Pro Asn Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2787 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2787 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Asn Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2788 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2788 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Asn Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2789 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2789 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Asn Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2790 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2790 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Asn Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2791 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2791 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Asn Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2792 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2792 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Asn 1 5 10 15 Trp Glu Phe Val 20 <210> 2793 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2793 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Asn Glu Phe Val 20 <210> 2794 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2794 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Asn Phe Val 20 <210> 2795 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (1)..(1) <223> Covalently bound to 400Mal-PEG <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2795 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Asn Val 20 <210> 2796 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2796 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Asn 20 <210> 2797 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2797 Gln Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2798 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2798 His Gln Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2799 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2799 His Leu Gln Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2800 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2800 His Leu Tyr Gln Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2801 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2801 His Leu Tyr Leu Gln Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2802 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2802 His Leu Tyr Leu Trp Gln Gln Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2803 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2803 His Leu Tyr Leu Trp Gln Ala Gln Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2804 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2804 His Leu Tyr Leu Trp Gln Ala Trp Gln Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2805 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2805 His Leu Tyr Leu Trp Gln Ala Trp Pro Gln Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2806 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2806 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Gln Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2807 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2807 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Gln Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2808 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2808 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Gln Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2809 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2809 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Gln Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2810 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2810 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Gln Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2811 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2811 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gln 1 5 10 15 Trp Glu Phe Val 20 <210> 2812 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2812 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Gln Glu Phe Val 20 <210> 2813 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2813 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Gln Phe Val 20 <210> 2814 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2814 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Gln Val 20 <210> 2815 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2815 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Gln 20 <210> 2816 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2816 Arg Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2817 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2817 His Arg Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2818 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2818 His Leu Arg Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2819 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2819 His Leu Tyr Arg Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2820 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2820 His Leu Tyr Leu Arg Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2821 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2821 His Leu Tyr Leu Trp Arg Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2822 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2822 His Leu Tyr Leu Trp Gln Ala Arg Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2823 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2823 His Leu Tyr Leu Trp Gln Ala Trp Arg Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2824 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2824 His Leu Tyr Leu Trp Gln Ala Trp Pro Arg Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2825 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2825 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Arg Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2826 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2826 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Arg Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2827 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2827 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Arg Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2828 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2828 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Arg Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2829 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2829 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Arg Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2830 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2830 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Arg 1 5 10 15 Trp Glu Phe Val 20 <210> 2831 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2831 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Arg Glu Phe Val 20 <210> 2832 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2832 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Arg Phe Val 20 <210> 2833 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2833 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Arg Val 20 <210> 2834 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2834 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Arg 20 <210> 2835 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2835 Thr Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2836 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2836 His Thr Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2837 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2837 His Leu Thr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2838 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2838 His Leu Tyr Thr Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2839 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2839 His Leu Tyr Leu Thr Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2840 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2840 His Leu Tyr Leu Trp Thr Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2841 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2841 His Leu Tyr Leu Trp Gln Thr Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2842 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2842 His Leu Tyr Leu Trp Gln Ala Thr Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2843 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2843 His Leu Tyr Leu Trp Gln Ala Trp Thr Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2844 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2844 His Leu Tyr Leu Trp Gln Ala Trp Pro Thr Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2845 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2845 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Thr Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2846 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2846 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Thr Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2847 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2847 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Thr Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2848 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2848 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Thr Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2849 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2849 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Thr Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2850 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2850 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Thr 1 5 10 15 Trp Glu Phe Val 20 <210> 2851 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2851 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Thr Glu Phe Val 20 <210> 2852 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2852 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Thr Phe Val 20 <210> 2853 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2853 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Thr Val 20 <210> 2854 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2854 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Thr 20 <210> 2855 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2855 Val Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2856 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2856 His Val Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2857 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2857 His Leu Val Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2858 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2858 His Leu Tyr Val Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2859 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2859 His Leu Tyr Leu Val Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2860 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2860 His Leu Tyr Leu Trp Val Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2861 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2861 His Leu Tyr Leu Trp Gln Val Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2862 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2862 His Leu Tyr Leu Trp Gln Ala Val Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2863 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2863 His Leu Tyr Leu Trp Gln Ala Trp Val Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2864 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2864 His Leu Tyr Leu Trp Gln Ala Trp Pro Val Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2865 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2865 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Val Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2866 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2866 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Val Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2867 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2867 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Val Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2868 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2868 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Val 1 5 10 15 Trp Glu Phe Val 20 <210> 2869 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2869 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Val Glu Phe Val 20 <210> 2870 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2870 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Val Phe Val 20 <210> 2871 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2871 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Val Val 20 <210> 2872 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2872 Trp Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2873 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2873 His Trp Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2874 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2874 His Leu Trp Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2875 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2875 His Leu Tyr Trp Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2876 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2876 His Leu Tyr Leu Trp Trp Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2877 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2877 His Leu Tyr Leu Trp Gln Trp Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2878 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2878 His Leu Tyr Leu Trp Gln Ala Trp Trp Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2879 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2879 His Leu Tyr Leu Trp Gln Ala Trp Pro Trp Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2880 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2880 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Trp Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2881 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2881 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Trp Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2882 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2882 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Trp Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2883 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2883 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Trp Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2884 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2884 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Trp 1 5 10 15 Trp Glu Phe Val 20 <210> 2885 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2885 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Trp Phe Val 20 <210> 2886 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2886 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Trp Val 20 <210> 2887 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2887 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Trp 20 <210> 2888 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2888 Tyr Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2889 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2889 His Tyr Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2890 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2890 His Leu Tyr Tyr Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2891 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2891 His Leu Tyr Leu Tyr Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2892 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2892 His Leu Tyr Leu Trp Tyr Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2893 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2893 His Leu Tyr Leu Trp Gln Tyr Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2894 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2894 His Leu Tyr Leu Trp Gln Ala Tyr Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2895 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2895 His Leu Tyr Leu Trp Gln Ala Trp Tyr Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2896 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2896 His Leu Tyr Leu Trp Gln Ala Trp Pro Tyr Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2897 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2897 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Tyr Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2898 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2898 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Tyr Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2899 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2899 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Tyr Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2900 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2900 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Tyr Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2901 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2901 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Tyr Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2902 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2902 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Tyr 1 5 10 15 Trp Glu Phe Val 20 <210> 2903 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2903 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Tyr Glu Phe Val 20 <210> 2904 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2904 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Tyr Phe Val 20 <210> 2905 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2905 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Tyr Val 20 <210> 2906 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2906 His Leu Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Tyr 20 <210> 2907 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (21)..(21) <223> N-ethylmaleiimido Cys <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2907 Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile Trp 1 5 10 15 Arg Asp Pro Ser Cys 20 <210> 2908 <211> 21 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-ethylmaleiimido Cys <220> <221> MISC_FEATURE <222> (21)..(21) <223> C-terminal amidation <400> 2908 Cys Val Tyr Glu Val Gly Trp Asp His Gly Asn Trp Tyr Glu Ile Ile 1 5 10 15 Trp Arg Asp Pro Ser 20 <210> 2909 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2909 His Lys Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2910 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2910 His Pro Tyr Leu Trp Gln Ala Trp Pro Ser Pro Trp Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2911 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2911 His Thr Tyr Leu Trp Gln Ala His Pro Ser Pro Asn Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2912 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2912 His Thr Tyr Leu Trp Gln Ala His Pro Ser Pro Glu Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2913 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2913 His Thr Tyr Leu Trp Gln Ala Tyr Pro Ser Pro Asn Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2914 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2914 His Thr Tyr Leu Trp Gln Ala Tyr Pro Ser Pro Glu Val Glu Val Gly 1 5 10 15 Trp Glu Phe Val 20 <210> 2915 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2915 His Thr Tyr Leu Trp Gln Ala His Pro Ser Pro Glu Val Glu Val Gly 1 5 10 15 Tyr Glu Phe Val 20 <210> 2916 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> N-terminal acetylation <220> <221> MISC_FEATURE <222> (20)..(20) <223> C-terminal amidation <400> 2916 Gln Thr Tyr Leu Trp Gln Ala His Pro Ser Pro Glu Val Glu Val Gly 1 5 10 15 Tyr Glu Phe Val 20 <210> 2917 <211> 636 <212> PRT <213> Homo sapiens <400> 2917 Arg Ala Asn Ser Leu Leu Glu Glu Thr Lys Gln Gly Asn Leu Glu Arg 1 5 10 15 Glu Cys Ile Glu Glu Leu Cys Asn Lys Glu Glu Ala Arg Glu Val Phe 20 25 30 Glu Asn Asp Pro Glu Thr Asp Tyr Phe Tyr Pro Lys Tyr Leu Val Cys 35 40 45 Leu Arg Ser Phe Gln Thr Gly Leu Phe Thr Ala Ala Arg Gln Ser Thr 50 55 60 Asn Ala Tyr Pro Asp Leu Arg Ser Cys Val Asn Ala Ile Pro Asp Gln 65 70 75 80 Cys Ser Pro Leu Pro Cys Asn Glu Asp Gly Tyr Met Ser Cys Lys Asp 85 90 95 Gly Lys Ala Ser Phe Thr Cys Thr Cys Lys Pro Gly Trp Gln Gly Glu 100 105 110 Lys Cys Glu Phe Asp Ile Asn Glu Cys Lys Asp Pro Ser Asn Ile Asn 115 120 125 Gly Gly Cys Ser Gln Ile Cys Asp Asn Thr Pro Gly Ser Tyr His Cys 130 135 140 Ser Cys Lys Asn Gly Phe Val Met Leu Ser Asn Lys Lys Asp Cys Lys 145 150 155 160 Asp Val Asp Glu Cys Ser Leu Lys Pro Ser Ile Cys Gly Thr Ala Val 165 170 175 Cys Lys Asn Ile Pro Gly Asp Phe Glu Cys Glu Cys Pro Glu Gly Tyr 180 185 190 Arg Tyr Asn Leu Lys Ser Lys Ser Cys Glu Asp Ile Asp Glu Cys Ser 195 200 205 Glu Asn Met Cys Ala Gln Leu Cys Val Asn Tyr Pro Gly Gly Tyr Thr 210 215 220 Cys Tyr Cys Asp Gly Lys Lys Gly Phe Lys Leu Ala Gln Asp Gln Lys 225 230 235 240 Ser Cys Glu Val Val Ser Val Cys Leu Pro Leu Asn Leu Asp Thr Lys 245 250 255 Tyr Glu Leu Leu Tyr Leu Ala Glu Gln Phe Ala Gly Val Val Leu Tyr 260 265 270 Leu Lys Phe Arg Leu Pro Glu Ile Ser Arg Phe Ser Ala Glu Phe Asp 275 280 285 Phe Arg Thr Tyr Asp Ser Glu Gly Val Ile Leu Tyr Ala Glu Ser Ile 290 295 300 Asp His Ser Ala Trp Leu Leu Ile Ala Leu Arg Gly Gly Lys Ile Glu 305 310 315 320 Val Gln Leu Lys Asn Glu His Thr Ser Lys Ile Thr Thr Gly Gly Asp 325 330 335 Val Ile Asn Asn Gly Leu Trp Asn Met Val Ser Val Glu Glu Leu Glu 340 345 350 His Ser Ile Ser Ile Lys Ile Ala Lys Glu Ala Val Met Asp Ile Asn 355 360 365 Lys Pro Gly Pro Leu Phe Lys Pro Glu Asn Gly Leu Leu Glu Thr Lys 370 375 380 Val Tyr Phe Ala Gly Phe Pro Arg Lys Val Glu Ser Glu Leu Ile Lys 385 390 395 400 Pro Ile Asn Pro Arg Leu Asp Gly Cys Ile Arg Ser Trp Asn Leu Met 405 410 415 Lys Gln Gly Ala Ser Gly Ile Lys Glu Ile Ile Gln Glu Lys Gln Asn 420 425 430 Lys His Cys Leu Val Thr Val Glu Lys Gly Ser Tyr Tyr Pro Gly Ser 435 440 445 Gly Ile Ala Gln Phe His Ile Asp Tyr Asn Asn Val Ser Ser Ala Glu 450 455 460 Gly Trp His Val Asn Val Thr Leu Asn Ile Arg Pro Ser Thr Gly Thr 465 470 475 480 Gly Val Met Leu Ala Leu Val Ser Gly Asn Asn Thr Val Pro Phe Ala 485 490 495 Val Ser Leu Val Asp Ser Thr Ser Glu Lys Ser Gln Asp Ile Leu Leu 500 505 510 Ser Val Glu Asn Thr Val Ile Tyr Arg Ile Gln Ala Leu Ser Leu Cys 515 520 525 Ser Asp Gln Gln Ser His Leu Glu Phe Arg Val Asn Arg Asn Asn Leu 530 535 540 Glu Leu Ser Thr Pro Leu Lys Ile Glu Thr Ile Ser His Glu Asp Leu 545 550 555 560 Gln Arg Gln Leu Ala Val Leu Asp Lys Ala Met Lys Ala Lys Val Ala 565 570 575 Thr Tyr Leu Gly Gly Leu Pro Asp Val Pro Phe Ser Ala Thr Pro Val 580 585 590 Asn Ala Phe Tyr Asn Gly Cys Met Glu Val Asn Ile Asn Gly Val Gln 595 600 605 Leu Asp Leu Asp Glu Ala Ile Ser Lys His Asn Asp Ile Arg Ala His 610 615 620 Ser Cys Pro Ser Val Trp Lys Lys Thr Lys Asn Ser 625 630 635 <210> 2918 <211> 3595 <212> DNA <213> Homo sapiens <300> <308> NCBI / NM_000313.3 <309> 2014-02-14 <313> (1)..(3595) <400> 2918 tttggaaacg tcacactgtg gaggaaaagc agcaactagg gagctggtga agaaggatgt 60 ctcagcagtg tttactaggc ctccaacact agagcccatc ccccagctcc gaaaagcttc 120 ctggaaatgt ccttgttatc acttcccctc tcgggctggg cgctgggagc gggcggtctc 180 ctccgccccc ggctgttccg ccgaggctcg ctgggtcgct ggcgccgccg cgcagcacgg 240 ctcagaccga ggcgcacagg ctcgcagctc cgcggcgcct agcgctccgg tccccgccgc 300 gacgcgccac cgtccctgcc ggcgcctccg cgcgcttcga aatgagggtc ctgggtgggc 360 gctgcggggc gctgctggcg tgtctcctcc tagtgcttcc cgtctcagag gcaaactttt 420 tgtcaaagca acaggcttca caagtcctgg ttaggaagcg tcgtgcaaat tctttacttg 480 aagaaaccaa acagggtaat cttgaaagag aatgcatcga agaactgtgc aataaagaag 540 aagccaggga ggtctttgaa aatgacccgg aaacggatta tttttatcca aaatacttag 600 tttgtcttcg ctcttttcaa actgggttat tcactgctgc acgtcagtca actaatgctt 660 atcctgacct aagaagctgt gtcaatgcca ttccagacca gtgtagtcct ctgccatgca 720 atgaagatgg atatatgagc tgcaaagatg gaaaagcttc ttttacttgc acttgtaaac 780 caggttggca aggagaaaag tgtgaatttg acataaatga atgcaaagat ccctcaaata 840 taaatggagg ttgcagtcaa atttgtgata atacacctgg aagttaccac tgttcctgta 900 aaaatggttt tgttatgctt tcaaataaga aagattgtaa agatgtggat gaatgctctt 960 tgaagccaag catttgtggc acagctgtgt gcaagaacat cccaggagat tttgaatgtg 1020 aatgccccga aggctacaga tataatctca aatcaaagtc ttgtgaagat atagatgaat 1080 gctctgagaa catgtgtgct cagctttgtg tcaattaccc tggaggttac acttgctatt 1140 gtgatgggaa gaaaggattc aaacttgccc aagatcagaa gagttgtgag gttgtttcag 1200 tgtgccttcc cttgaacctt gacacaaagt atgaattact ttacttggcg gagcagtttg 1260 caggggttgt tttatattta aaatttcgtt tgccagaaat cagcagattt tcagcagaat 1320 ttgatttccg gacatatgat tcagaaggcg tgatactgta cgcagaatct atcgatcact 1380 cagcgtggct cctgattgca cttcgtggtg gaaagattga agttcagctt aagaatgaac 1440 atacatccaa aatcacaact ggaggtgatg ttattaataa tggtctatgg aatatggtgt 1500 ctgtggaaga attagaacat agtattagca ttaaaatagc taaagaagct gtgatggata 1560 taaataaacc tggacccctt tttaagccgg aaaatggatt gctggaaacc aaagtatact 1620 ttgcaggatt ccctcggaaa gtggaaagtg aactcattaa accgattaac cctcgtctag 1680 atggatgtat acgaagctgg aatttgatga agcaaggagc ttctggaata aaggaaatta 1740 ttcaagaaaa acaaaataag cattgcctgg ttactgtgga gaagggctcc tactatcctg 1800 gttctggaat tgctcaattt cacatagatt ataataatgt atccagtgct gagggttggc 1860 atgtaaatgt gaccttgaat attcgtccat ccacgggcac tggtgttatg cttgccttgg 1920 tttctggtaa caacacagtg ccctttgctg tgtccttggt ggactccacc tctgaaaaat 1980 cacaggatat tctgttatct gttgaaaata ctgtaatata tcggatacag gccctaagtc 2040 tatgttccga tcaacaatct catctggaat ttagagtcaa cagaaacaat ctggagttgt 2100 cgacaccact taaaatagaa accatctccc atgaagacct tcaaagacaa cttgccgtct 2160 tggacaaagc aatgaaagca aaagtggcca catacctggg tggccttcca gatgttccat 2220 tcagtgccac accagtgaat gccttttata atggctgcat ggaagtgaat attaatggtg 2280 tacagttgga tctggatgaa gccatttcta aacataatga tattagagct cactcatgtc 2340 catcagtttg gaaaaagaca aagaattctt aaggcatctt ttctctgctt ataatacctt 2400 ttccttgtgt gtaattatac ttatgtttca ataacagctg aagggtttta tttacaatgt 2460 gcagtctttg attattttgt ggtcctttcc tgggattttt aaaaggtcct ttgtcaagga 2520 aaaaaattct gttgtgatat aaatcacagt aaagaaattc ttacttctct tgctatctaa 2580 gaatagtgaa aaataacaat tttaaatttg aatttttttc ctacaaatga cagtttcaat 2640 ttttgtttgt aaaactaaat tttaatttta tcatcatgaa ctagtgtcta aatacctatg 2700 tttttttcag aaagcaagga agtaaactca aacaaaagtg cgtgtaatta aatactatta 2760 atcataggca gatactattt tgtttatgtt tttgtttttt tcctgatgaa ggcagaagag 2820 atggtggtct attaaatatg aattgaatgg agggtcctaa tgccttattt caaaacaatt 2880 cctcaggggg aacagctttg gcttcatctt tctcttgtgt ggcttcacat ttaaaccagt 2940 atctttattg aattagaaaa caagtgggac atattttcct gagagcagca caggaatctt 3000 cttcttggca gctgcagtct gtcaggatga gatatcagat taggttggat aggtggggaa 3060 atctgaagtg ggtacatttt ttaaattttg ctgtgtgggt cacacaaggt ctacattaca 3120 aaagacagaa ttcagggatg gaaaggagaa tgaacaaatg tgggagttca tagttttcct 3180 tgaatccaac ttttaattac cagagtaagt tgccaaaatg tgattgttga agtacaaaag 3240 gaactatgaa aaccagaaca aattttaaca aaaggacaac cacagaggga tatagtgaat 3300 atcgtatcat tgtaatcaaa gaagtaagga ggtaagattg ccacgtgcct gctggtactg 3360 tgatgcattt caagtggcag ttttatcacg tttgaatcta ccattcatag ccagatgtgt 3420 atcagatgtt tcactgacag tttttaacaa taaattcttt tcactgtatt ttatatcact 3480 tataataaat cggtgtataa ttttaaaatg catgtgaata tctttattat atcaactgtt 3540 tgaataaaac aaaattacat aatagacatt taactcttca aaaaaaaaaa aaaaa 3595 <210> 2919 <211> 676 <212> PRT <213> Homo sapiens <300> <308> NCBI / NP_000304.2 <309> 2014-02-14 <313> (1)..(676) <400> 2919 Met Arg Val Leu Gly Gly Arg Cys Gly Ala Leu Leu Ala Cys Leu Leu 1 5 10 15 Leu Val Leu Pro Val Ser Glu Ala Asn Phe Leu Ser Lys Gln Gln Ala 20 25 30 Ser Gln Val Leu Val Arg Lys Arg Arg Ala Asn Ser Leu Leu Glu Glu 35 40 45 Thr Lys Gln Gly Asn Leu Glu Arg Glu Cys Ile Glu Glu Leu Cys Asn 50 55 60 Lys Glu Glu Ala Arg Glu Val Phe Glu Asn Asp Pro Glu Thr Asp Tyr 65 70 75 80 Phe Tyr Pro Lys Tyr Leu Val Cys Leu Arg Ser Phe Gln Thr Gly Leu 85 90 95 Phe Thr Ala Ala Arg Gln Ser Thr Asn Ala Tyr Pro Asp Leu Arg Ser 100 105 110 Cys Val Asn Ala Ile Pro Asp Gln Cys Ser Pro Leu Pro Cys Asn Glu 115 120 125 Asp Gly Tyr Met Ser Cys Lys Asp Gly Lys Ala Ser Phe Thr Cys Thr 130 135 140 Cys Lys Pro Gly Trp Gln Gly Glu Lys Cys Glu Phe Asp Ile Asn Glu 145 150 155 160 Cys Lys Asp Pro Ser Asn Ile Asn Gly Gly Cys Ser Gln Ile Cys Asp 165 170 175 Asn Thr Pro Gly Ser Tyr His Cys Ser Cys Lys Asn Gly Phe Val Met 180 185 190 Leu Ser Asn Lys Lys Asp Cys Lys Asp Val Asp Glu Cys Ser Leu Lys 195 200 205 Pro Ser Ile Cys Gly Thr Ala Val Cys Lys Asn Ile Pro Gly Asp Phe 210 215 220 Glu Cys Glu Cys Pro Glu Gly Tyr Arg Tyr Asn Leu Lys Ser Lys Ser 225 230 235 240 Cys Glu Asp Ile Asp Glu Cys Ser Glu Asn Met Cys Ala Gln Leu Cys 245 250 255 Val Asn Tyr Pro Gly Gly Tyr Thr Cys Tyr Cys Asp Gly Lys Lys Gly 260 265 270 Phe Lys Leu Ala Gln Asp Gln Lys Ser Cys Glu Val Val Ser Val Cys 275 280 285 Leu Pro Leu Asn Leu Asp Thr Lys Tyr Glu Leu Leu Tyr Leu Ala Glu 290 295 300 Gln Phe Ala Gly Val Val Leu Tyr Leu Lys Phe Arg Leu Pro Glu Ile 305 310 315 320 Ser Arg Phe Ser Ala Glu Phe Asp Phe Arg Thr Tyr Asp Ser Glu Gly 325 330 335 Val Ile Leu Tyr Ala Glu Ser Ile Asp His Ser Ala Trp Leu Leu Ile 340 345 350 Ala Leu Arg Gly Gly Lys Ile Glu Val Gln Leu Lys Asn Glu His Thr 355 360 365 Ser Lys Ile Thr Thr Gly Gly Asp Val Ile Asn Asn Gly Leu Trp Asn 370 375 380 Met Val Ser Val Glu Glu Leu Glu His Ser Ile Ser Ile Lys Ile Ala 385 390 395 400 Lys Glu Ala Val Met Asp Ile Asn Lys Pro Gly Pro Leu Phe Lys Pro 405 410 415 Glu Asn Gly Leu Leu Glu Thr Lys Val Tyr Phe Ala Gly Phe Pro Arg 420 425 430 Lys Val Glu Ser Glu Leu Ile Lys Pro Ile Asn Pro Arg Leu Asp Gly 435 440 445 Cys Ile Arg Ser Trp Asn Leu Met Lys Gln Gly Ala Ser Gly Ile Lys 450 455 460 Glu Ile Ile Gln Glu Lys Gln Asn Lys His Cys Leu Val Thr Val Glu 465 470 475 480 Lys Gly Ser Tyr Tyr Pro Gly Ser Gly Ile Ala Gln Phe His Ile Asp 485 490 495 Tyr Asn Asn Val Ser Ser Ala Glu Gly Trp His Val Asn Val Thr Leu 500 505 510 Asn Ile Arg Pro Ser Thr Gly Thr Gly Val Met Leu Ala Leu Val Ser 515 520 525 Gly Asn Asn Thr Val Pro Phe Ala Val Ser Leu Val Asp Ser Thr Ser 530 535 540 Glu Lys Ser Gln Asp Ile Leu Leu Ser Val Glu Asn Thr Val Ile Tyr 545 550 555 560 Arg Ile Gln Ala Leu Ser Leu Cys Ser Asp Gln Gln Ser His Leu Glu 565 570 575 Phe Arg Val Asn Arg Asn Asn Leu Glu Leu Ser Thr Pro Leu Lys Ile 580 585 590 Glu Thr Ile Ser His Glu Asp Leu Gln Arg Gln Leu Ala Val Leu Asp 595 600 605 Lys Ala Met Lys Ala Lys Val Ala Thr Tyr Leu Gly Gly Leu Pro Asp 610 615 620 Val Pro Phe Ser Ala Thr Pro Val Asn Ala Phe Tyr Asn Gly Cys Met 625 630 635 640 Glu Val Asn Ile Asn Gly Val Gln Leu Asp Leu Asp Glu Ala Ile Ser 645 650 655 Lys His Asn Asp Ile Arg Ala His Ser Cys Pro Ser Val Trp Lys Lys 660 665 670 Thr Lys Asn Ser 675 <210> 2920 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <400> 2920 Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr Tyr Glu Phe 1 5 10 15 <210> 2921 <211> 16 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Tle, Val, D-Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (2)..(2) <223> Xaa is Ala, Cys, Asp, Dap, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, D-Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (3)..(3) <223> Xaa is Ala, D-Ala, Aib, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, D-Ser, Thr, Tle, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (4)..(4) <223> Xaa is Ala, D-Ala, Aib, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Nmg, Pro, D-Pro, Gln, Arg, Ser, D-Ser, Thr, Tle, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (5)..(5) <223> Xaa is 1Ni, 2Ni, Ala, Bta, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, D-Trp, or Tyr <220> <221> MISC_FEATURE <222> (6)..(6) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, Tyr, or D-Trp <220> <221> MISC_FEATURE <222> (7)..(7) <223> Xaa is Ala, Cys, Asp, D-Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, D-Trp, or Tyr <220> <221> MISC_FEATURE <222> (8)..(8) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, Tyr, or D-Trp <220> <221> MISC_FEATURE <222> (9)..(9) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, D-Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (10)..(10) <223> Xaa is Ala, D-Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, D-Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (11)..(11) <223> Xaa is Ala, Cys, Asp, D-Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (12)..(12) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, D-Thr, Tle, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (13)..(13) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (14)..(14) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Nle, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, Tyr, or D-Tyr <220> <221> MISC_FEATURE <222> (15)..(15) <223> Xaa is Ala, Cys, Asp, Glu, D-Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (16)..(16) <223> Xaa is Ala, Cys, Asp, Glu, Phe, D-Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <400> 2921 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa 1 5 10 15 <210> 2922 <211> 19 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Tle, Val, Trp, Tyr, or D-Tyr <220> <221> MISC_FEATURE <222> (2)..(2) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, D-Val, Trp, Tyr, or D-Tyr <220> <221> MISC_FEATURE <222> (3)..(3) <223> Xaa is Ala, Bpa, Cys, Asp, Glu, D-Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (4)..(4) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Tle, Val, D-Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (5)..(5) <223> Xaa is Ala, Cys, Asp, Dap, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, D-Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (6)..(6) <223> Xaa is Ala, D-Ala, Aib, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, D-Ser, Thr, Tle, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (7)..(7) <223> Xaa is Ala, D-Ala, Aib, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Nmg, Pro, D-Pro, Gln, Arg, Ser, D-Ser, Thr, Tle, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (8)..(8) <223> Xaa is 1Ni, 2Ni, Ala, Bta, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, D-Trp, or Tyr <220> <221> MISC_FEATURE <222> (9)..(9) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, Tyr, or D-Trp <220> <221> MISC_FEATURE <222> (10)..(10) <223> Xaa is Ala, Cys, Asp, D-Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, D-Trp, or Tyr <220> <221> MISC_FEATURE <222> (11)..(11) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, Tyr, or D-Trp <220> <221> MISC_FEATURE <222> (12)..(12) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, D-Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (13)..(13) <223> Xaa is Ala, D-Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, D-Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (14)..(14) <223> Xaa is Ala, Cys, Asp, D-Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (15)..(15) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, D-Thr, Tle, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (16)..(16) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (17)..(17) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Nle, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, Tyr, or D-Tyr <220> <221> MISC_FEATURE <222> (18)..(18) <223> Xaa is Ala, Cys, Asp, Glu, D-Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (19)..(19) <223> Xaa is Ala, Cys, Asp, Glu, Phe, D-Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <400> 2922 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa 1 5 10 15 Xaa Xaa Xaa <210> 2923 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <220> <221> MISC_FEATURE <222> (1)..(1) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Tle, Val, Trp, Tyr, or D-Tyr <220> <221> MISC_FEATURE <222> (2)..(2) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, D-Val, Trp, Tyr, or D-Tyr <220> <221> MISC_FEATURE <222> (3)..(3) <223> Xaa is Ala, Bpa, Cys, Asp, Glu, D-Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (4)..(4) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Tle, Val, D-Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (5)..(5) <223> Xaa is Ala, Cys, Asp, Dap, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, D-Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (6)..(6) <223> Xaa is Ala, D-Ala, Aib, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, D-Ser, Thr, Tle, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (7)..(7) <223> Xaa is Ala, D-Ala, Aib, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Nmg, Pro, D-Pro, Gln, Arg, Ser, D-Ser, Thr, Tle, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (8)..(8) <223> Xaa is 1Ni, 2Ni, Ala, Bta, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, D-Trp, or Tyr <220> <221> MISC_FEATURE <222> (9)..(9) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, Tyr, or D-Trp <220> <221> MISC_FEATURE <222> (10)..(10) <223> Xaa is Ala, Cys, Asp, D-Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, D-Trp, or Tyr <220> <221> MISC_FEATURE <222> (11)..(11) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, Tyr, or D-Trp <220> <221> MISC_FEATURE <222> (12)..(12) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, D-Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (13)..(13) <223> Xaa is Ala, D-Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, D-Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (14)..(14) <223> Xaa is Ala, Cys, Asp, D-Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (15)..(15) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, D-Thr, Tle, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (16)..(16) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (17)..(17) <223> Xaa is Ala, Cys, Asp, Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Nle, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, Tyr, or D-Tyr <220> <221> MISC_FEATURE <222> (18)..(18) <223> Xaa is Ala, Cys, Asp, Glu, D-Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (19)..(19) <223> Xaa is Ala, Cys, Asp, Glu, Phe, D-Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, or Tyr <220> <221> MISC_FEATURE <222> (20)..(20) <223> Xaa is Ala, Cys, Asp, Glu, D-Glu, Phe, Gly, His, Ile, Lys, Leu, Met, Asn, Pro, D-Pro, Gln, Arg, Ser, Thr, Val, Trp, and Tyr <400> 2923 Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa Xaa 1 5 10 15 Xaa Xaa Xaa Xaa 20 <210> 2924 <211> 20 <212> PRT <213> Artificial Sequence <220> <223> Synthetic peptide <400> 2924 Glu Tyr Tyr Val Ser Ala Gly Trp Tyr Asp Tyr Asn Thr Asp Thr Tyr 1 5 10 15 Tyr Glu Phe Glu 20

Claims (27)

  1. 아미노산 서열 VSAGWYDYNTDTYYEF (서열번호 2920)와 최소 50% 동일한 아미노산 서열을 포함하고 화학식 I의 구조를 갖는 펩티드:
    [화학식 I]
    X1004-X1005-X1006-X1007-X1008-X1009-X1010-X1011-X1012-X1013-X1014-X1015-X1016-X1017-X1018-X1019,
    상기 X1004는 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, Tle, V, v, W, 또는 Y;
    상기 X1005는 A, C, D, Dap, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, s, T, V, W, 또는 Y;
    상기 X1006은 A, a, Aib, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, s, T, Tle, V, W, 또는 Y;
    상기 X1007은 A, a, Aib, C, D, E, F, G, H, I, K, L, M, N, Nmg, P, p, Q, R, S, s, T, Tle, V, W, 또는 Y;
    상기 X1008은 1Ni, 2Ni, A, Bta, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, w, 또는 Y;
    상기 X1009는 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, Y, 또는 w;
    상기 X1010은 A, C, D, d, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, w, 또는 Y;
    상기 X1011은 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, Y, 또는 w;
    상기 X1012는 A, C, D, E, F, G, H, I, K, L, M, N, n, P, p, Q, R, S, T, V, W, 또는 Y;
    상기 X1013은 A, a, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, t, V, W, 또는 Y;
    상기 X1014는 A, C, D, d, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y;
    상기 X1015는 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, t, Tle, V, W, 또는 Y;
    상기 X1016은 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y;
    상기 X1017은 A, C, D, E, F, G, H, I, K, L, M, N, Nle, P, p, Q, R, S, T, V, W, Y, 또는 y;
    상기 X1018은 A, C, D, E, e, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y; 및
    상기 X1019는 A, C, D, E, F, f, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y (서열번호 2921)임.
  2. 제1항에 있어서,
    상기 펩티드는 X1004에 직접적으로 연결된 1 종 이상의 N-말단 아미노산(들)을 추가적으로 포함하며, 상기 N-말단 아미노산(들)은 X1003, X1002-X1003, 및 X1001-X1002-X1003으로 이루어진 군으로부터 선택되는 아미노산 서열을 포함하고,
    상기 X1003은 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, Tle, V, W, Y, 또는 y;
    상기 X1002는 A, C, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, Y, 또는 y; 및
    상기 X1001은 A, Bpa, C, D, E, e, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y (서열번호 2922)인 것인 펩티드.
  3. 제1항 또는 제2항에 있어서,
    상기 펩티드는 X1019에 직접적으로 연결된 C-말단 아미노산을 추가적으로 포함하며, A, C, D, E, e, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 및 Y (서열번호 2923)로 이루어진 군으로부터 선택되는 것인 펩티드.
  4. 제1항에 있어서,
    상기 X1004는 A, E, F, G, H, I, K, L, M, N, P, Q, R, T, V, W, 또는 Y;
    상기 X1005는 A, D, E, F, G, H, I, K, L, M, N, R, S, T, V, W, 또는 Y;
    상기 X1006은 A, a, F, G, H, I, L, M, P, S, T, V, W, 또는 Y;
    상기 X1007은 G 또는 a;
    상기 X1008은 F, H, L, W, 또는 Y;
    상기 X1009는 F 또는 Y;
    상기 X1010은 A, D, E, F, G, H, I, K, L, M, N, Q, R, S, T, V, W, 또는 Y;
    상기 X1011은 A, E, F, G, H, I, K, L, M, N, P, Q, R, S, T, V, W, 또는 Y;
    상기 X1012는 A, D, E, F, G, H, I, K, L, M, N, n, P, Q, R, S, T, V, W, 또는 Y;
    상기 X1013은 A, D, E, F, G, H, I, K, L, M, N, Q, R, S, T, V, W, 또는 Y;
    상기 X1014는 A, D, d, E, G, H, N, Q, 또는 S;
    상기 X1015는 A, D, E, , F G, H, I, K, L, M, N, Q, R, S, T, V, W, 또는 Y;
    상기 X1016은 A, D, E, F, H, I, L, M, N, S, T, W, 또는 Y;
    상기 X1017은 A, D, E, F, G, H, I, K, L, M, N, Q, R, S, T, V, W, 또는 Y;
    상기 X1018은 A, D, E, F, G, H, I, K, L, M, N, P, Q, R, S, T, V, W, 또는 Y; 및
    상기 X1019는 E, F, f, H, I, L, M, V, W, 또는 Y인 것인 펩티드.
  5. 제4항에 있어서,
    상기 X1004는 A, F, H, I, K, L, T, V, W, 또는 Y;
    상기 X1005는 A, E, F, G, H, I, K, L, M, N, Q, R, S, T, V, W, 또는 Y;
    상기 X1006은 A, F, G, I, L, M, V, W, 또는 Y;
    상기 X1007은 G;
    상기 X1008은 F, L, W, 또는 Y;
    상기 X1010은 A, D, E, F, H, I, K, L, M, N, Q, R, S, T, V, W, 또는 Y;
    상기 X1011은 A, F, G, H, I, K, L, M, N, R, S, T, V, W, 또는 Y;
    상기 X1012는 A, D, E, F, G, H, I, K, L, M, N, n, P, Q, R, S, T, V, W, 또는 Y;
    상기 X1014는 D, d, E, G, H, 또는 N;
    상기 X1016은 D, E, F, H, S, W, 또는 Y; 및
    상기 X1019는 F, I, M, W, 또는 Y인 것인 펩티드.
  6. 제5항에 있어서,
    상기 X1004는 A, F, I, L, T, V, 또는 W;
    상기 X1005는 A, E, F, G, H, I, K, L, M, R, S, T, V, W, 또는 Y;
    상기 X1006은 A, F, G, I, L, V, W, 또는 Y;
    상기 X1008은 F 또는 W;
    상기 X1010은 D, E, F, H, I, K, L, N, Q, V, W, 또는 Y;
    상기 X1011은 F, G, I, K, L, M, R, T, V, W, 또는 Y;
    상기 X1012는 A, D, E, F, G, H, I, K, L, N, Q, R, S, T, V, 또는 Y;
    상기 X1013은 D, E, F, G, H, I, K, L, Q, R, S, T, V, 또는 W;
    상기 X1014는 D, E, 또는 H;
    상기 X1015는 D, E, H, I, K, M, Q, R, S, T, V, 또는 W;
    상기 X1016은 F, H, W, 또는 Y;
    상기 X1017은 D, E, G, H, I, T, W, 또는 Y;
    상기 X1018은 A, D, E, G, H, I, K, L, M, P, Q, R, S, T, V, 또는 W; 및
    상기 X1019는 F, I, M, 또는 W인 것인 펩티드.
  7. 제1항 내지 제6항 중 어느 한 항에 있어서,
    상기 X1004는 V, X1005는 S, X1006은 A, X1007은 G, X1008은 W, 및 X1009는 Y인 것인 펩티드.
  8. 제1항 내지 제7항 중 어느 한 항에 있어서,
    상기 아미노산 서열은 아미노산 서열 VSAGWYDYNTDTYYEF (서열번호 2920)와 최소 약 75% 동일성(identity), 최소 약 80% 동일성, 또는 최소 약 90% 동일성인 것을 포함하는 것인 펩티드.
  9. 제8항에 있어서,
    상기 아미노산 서열은 아미노산 서열 VSAGWYDYNTDTYYEF (서열번호 2920)를 포함하는 것인 펩티드.
  10. 제1항 내지 제9항 중 어느 한 항에 있어서,
    상기 펩티드는 X1004에 직접적으로 연결된 1 종 이상의 N-말단 아미노산(들)을 추가적으로 포함하며, 상기 N-말단 아미노산(들)은 X1003, X1002-X1003, 및 X1001-X1002-X1003로 이루어진 군으로부터 선택되는 아미노산 서열을 포함하고,
    상기 X1003은 A, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, y, 또는 Y;
    상기 X1002는 A, D, E, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, y, 또는 Y; 및
    상기 X1001은 A, D, E, e, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 또는 Y인 것인 펩티드.
  11. 제10항에 있어서,
    상기 X1003은 A, E, F, G, H, I, K, L, N, P, R, T, V, W, y, 또는 Y; 및
    상기 X1002는 A, D, E, F, G, H, I, K, L, N, P, R, T, V, W, y, 또는 Y인 것인 펩티드.
  12. 제4항 내지 제11항 중 어느 한 항에 있어서,
    상기 펩티드는 X1019에 직접적으로 연결된 C-말단 아미노산을 추가적으로 포함하며, A, D, E, e, F, G, H, I, K, L, M, N, P, p, Q, R, S, T, V, W, 및 Y로 이루어진 군으로부터 선택되는 것인 펩티드.
  13. 제12항에 있어서,
    상기 펩티드는 아미노산 서열 EYYVSAGWYDYNTDTYYEFE (서열번호 2924)와 최소 약 50% 동일성(identity), 최소 약 60% 동일성, 최소 약 70% 동일성, 최소 약 80% 동일성, 최소 약 90% 동일성, 최소 약 95% 동일성 또는 100% 동일한 아미노산 서열을 포함하는 것인 펩티드.
  14. 제1항 내지 제13항 중 어느 한 항에 있어서,
    상기 펩티드는 추적자(tracer)로서 서열번호 1의 아미노산 서열로 구성된 펩티드를 이용하는 경쟁적(competitive) LANCE 분석에서 25 nM 미만, 10 nM 미만, 5 nM 미만, 3 nM 미만, 또는 1 nM 미만의 IC50으로 인간 단백질 S에 결합하는 것인 펩티드
  15. EYYVSAGWYDYNTDTYYEFE(서열번호 2924)와 최소 약 80% 동일한 아미노산 서열로 구성된 펩티드.
  16. 서열번호 1-2916, 2920, 및 2924로 이루어진 군으로부터 선택된 아미노산 서열을 포함하는 펩티드.
  17. 제1항 내지 제16항 중 어느 한 항에 있어서,
    상기 펩티드는 PEG(polyethylene glycol) 모이어티(moiety), HSA(human serum albumin), 이의 항체 또는 단편, 히드록시에틸 전분(hydroxyethyl starch), 프롤린-알라닌-세린 다량체(proline-alanine-serine multimer, PASylation), C12-C18 지방산 또는 폴리시알산에 컨쥬게이션되는(conjugated) 것인 펩티드.
  18. 제1항 내지 제17항 중 어느 한 항에 있어서,
    상기 펩티드는 Bpa, Bpa-K(Bio)-C, C(Atf-Bio), C(Atf-LC-Bio), C(FeBABE), C(MalCy5), C(NEM), C(PEG), K, K(Ac), K(Ttds), K(Ttds-γGlu), K(Glutar), K(Ttds-Mal), T, Ttds, 또는 Ttds-K(Bio)로 이루어진 군으로부터 선택된 모이어티에 컨쥬게이션(conjugated) 또는 부착되는(attached) 것인 펩티드.
  19. 제1항 내지 제18항 중 어느 한 항에 있어서,
    상기 펩티드는 단백질 S 활성을 억제하는 것인 펩티드.
  20. 제1항 내지 제19항 중 어느 한 항의 펩티드 및 약학적으로 허용가능한 담체를 포함하는 약학적 조성물.
  21. 약제에 사용하기 위한 제1항 내지 제19항 중 어느 한 항의 펩티드.
  22. 혈액 응고 질환의 치료에 사용하기 위한 제21항의 펩티드.
  23. 약제의 제조에서의 제1항 내지 제19항 중 어느 한 항의 펩티드의 용도.
  24. 제23항에 있어서,
    상기 약제는 혈액 응고 질환의 치료를 위한 것인 용도.
  25. 개체(subject)에서의 단백질 S 활성을 억제시키는 방법으로서,
    상기 방법은 상기 개체에게 단백질 S의 활성을 억제하기에 효과적인 양의 제1항 내지 제19항 중 어느 한 항의 펩티드를 투여하는 단계를 포함하는 것인 방법.
  26. 질환으로 고통받거나 질환으로 고통받을 위험이 있는 개체를 치료하기 위한 방법으로서, 상기 방법은 상기 개체에게 제1항 내지 제19항 중 어느 한 항의 펩티드를 투여하는 단계를 포함하는 것인 방법.
  27. 제26항에 있어서,
    상기 질환은 혈액 응고 질환인 것인 방법.
KR1020167026913A 2014-02-28 2015-02-27 펩티드 및 사용 방법 KR20160126075A (ko)

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