KR20150110850A - Ozone ointment and method of manufacturing cosmetics using beta-glucan and hyaluronic acid - Google Patents

Abstract

The present invention relates to a cosmetic which increases a sterilizing and regenerating effect of ozone, which influences acne-prone skin, using an ozone ointment, hyaluronic acid and β-glucan and can treat acne.

Description

Ozone ointment and method of manufacturing cosmetics using beta-glucan and hyaluronic acid {Omitted}

The present invention relates to ozone ointment produced using olive oil and ozone gas, and cosmetics which are completed by mixing betaglucan and hyaluronic acid.

Recently, modern people are exposed to water pollution and environmental pollution, and various kinds of chemical substances are exposed to various skin diseases in residential space.

Recently, studies have shown that ozone has excellent therapeutic effects on skin diseases including bacterial, viral, and fungal infections, and there have been attempts to use ozone in the treatment of skin diseases. The gaseous ozone has a short half-life, so that it is difficult to keep the ozone for a long time even if the ozone is used in a gaseous state or dissolved in water, so that a product capable of sufficiently exhibiting the sterilizing function of ozone has not been developed.

As of 2010, Korea's cosmetics market ranked 12th in the world with 2.1% of the world's $ 4.6 billion acne market. The market size of acne market was 8 billion at the beginning of the market in 1998, but it has developed rapidly and is now reaching 100 billion.

The global acne market is expected to grow by 0.7% annually from US $ 2.8 billion in 2009 to US $ 3.0 billion by 2016. The Korean cosmetic market for acne in 2012 is estimated at KRW100 billion, It is not only a bacterial infection disease or an inflammatory disease that occurs in hair follicles, but also a chronic disease which is continuously and repeatedly affected by stress and male hormone, and it is necessary to continuously manage and treat it.

The main purpose of treating and managing acne mainly is to maintain the appearance beauty from acne lesions, to reduce scarring, and because acne affects the quality of life through interpersonal and emotional quality, medicines including ointment and external medicine are very effective as therapeutic agents , While at the same time side effects from the drug may occur.

In order to solve these problems, there have been active efforts to utilize natural materials having a high antimicrobial effect worldwide, safety of acne skin, ease of development, and safety for development of therapeutic agents.

In the present invention, ozone ointment produced using olive oil and ozone gas, and beta glucan and hyaluronic acid are mixed to produce a cosmetic product.

The present invention proposes a technology for developing cosmetics for treating acne which can effectively promote the sterilizing function of the skin using ozone ointment and maximize the moisturizing effect.

Generating oxygen and using it to generate ozone (s100);

a step (s200) of bubbling the ozone generated in step 100 into a bubble in the cooling device 100 to perform bubble discharge;

Reacting ozone and olive oil in a cooling device (s300);

The step of treating the ozone after step S300 (S400)

Mixing the ozone-treated olive oil, the betaclucan and the hyaluronic acid with the ozone-treated olive oil so that the weight of each of the beta-glucan and the hyaluronic acid is 0.1 to 0.3% by weight (s1000);

≪ / RTI >

In step s100,

Air is taken in the air to generate oxygen through the oxygen generator unit 200 and then generated oxygen is pumped to flow oxygen A1 along the oxygen supply pipe 210 toward the cooling unit 100 Sending (S110),

(S120) of cooling the oxygen drawn into the cooling pipe 250 in the cooling unit 100 from 3 to 7 degrees Celsius,

A step (s130) of passing through the water removing unit 280 for removing oxygen (A2, A3) from the cooling device unit 100 having the cooling pipe 250 and removing water contained in the oxygen cooling,

And the oxygen (A4) from which moisture has been removed is drawn into the ozone generator 300 to generate ozone at a concentration of 1700 to 2000 ppm (s140)

Beta-glucan and hyaluronic acid have an acidity of 7.2 to 7.4 pH,

Ozone ointment and a method for manufacturing cosmetics using beta-glucan and hyaluronic acid are presented.

In order to prepare an ozone ointment in which olive oil and ozone are reacted with ozone ointment prepared by reacting olive oil with ozone ointment and mixing with beta glucan and hyaluronic acid having an acidity of 7.2 to 7.4, , Generating ozone and using it to generate ozone (s100); a step (s200) of bubbling the ozone generated in step 100 into a bubble in the cooling device 100 to perform bubble discharge; Reacting ozone and olive oil in a cooling device (s300); (step s210) in which the ozone generated in step s100 is introduced into the cooling device unit 100 along the ozone supply pipe 310, after step s100, (S220) of passing moisture removed from the ozone through the water removing unit 400 and removing the moisture removed in S220 from the cooling unit 100 through the water discharge pipe 410 The ozone is supplied to the bubble ejection apparatus 800 on the lower side of the reaction apparatus unit 500 in which ozone and olive oil react with each other (S300) of reacting the ozone with the olive oil after the step (s240) is performed. The reaction unit 500 is formed into a cylinder-shaped cylindrical shape, and the ozone is supplied to the reaction unit 500, The amount to be fed into the reactor is to be 3 to 6 liters per minute This cosmetic method using ozone ointments and beta-glucan and hyaluronic acid are presented.

Ozone ointment produces cosmetics using only ozone gas and pure olive olive oil, so there are no side effects from steroids, and there is no fear of secondary infection due to strong oxidizing power and sterilizing power.

1 is a block diagram of the ozone ointment manufacturing process
2 is a photograph of the inside of a cooling apparatus of an actual apparatus of the present invention.
3 is a photograph of an oxygen generator and an ozone generator.
4 and 6 are ozone bubble ejection apparatuses.

The present invention relates to cosmetics capable of increasing the sterilizing regeneration effect of ozone on acne skin by using ozone ointment, hyaluronic acid and beta glucan, and treating acne.

I. Ozone ointment  Manufacturing stage

Generating oxygen and using it to generate ozone (s100);

a step (s200) of bubbling the ozone generated in step 100 into a bubble in the cooling device 100 to perform bubble discharge;

Reacting ozone and olive oil in a cooling device (s300);

and a processing apparatus (400) for treating ozone after step S300,

In step s100,

Air is taken in the air to generate oxygen through the oxygen generator unit 200 and then generated oxygen is pumped to flow oxygen A1 along the oxygen supply pipe 210 toward the cooling unit 100 Sending (S110),

(S120) of cooling the oxygen drawn into the cooling pipe 250 in the cooling unit 100 from 3 to 7 degrees Celsius,

A step (s130) of passing through the water removing unit 280 for removing oxygen (A2, A3) from the cooling device unit 100 having the cooling pipe 250 and removing water contained in the oxygen cooling,

And the oxygen (A4) from which moisture has been removed is drawn into the ozone generator 300 to generate ozone at a concentration of 1700 to 2000 ppm (s140)

After step s100,

(s210) in which the ozone generated in step s100 is introduced into the cooling device unit 100 along the ozone supply pipe 310,

Removing the water remaining in the ozone through the water removing unit 400 (s220)

(s230) discharging the moisture removed in step S220 to the outside of the cooling apparatus unit 100 through the water discharge pipe 410,

After the ozone with moisture removed flows along the ozone supply pipe 330 and is supplied to the bubble discharge device 800 on the lower side of the reaction device unit 500 in which the ozone and the olive oil are reacted, The step (s300) of reacting the ozone with the olive oil is performed.

On the other hand, in step S 400, the ozone ointment oil, which is ozonized oil, which is a semi-solid ozonized oil produced after step s300, is obtained through the ozonization discharge pipe 570. At step S400, The ozone which is not completely formed is discharged to the ozone treatment unit 600 through the ozone discharge pipe 580. In the ozone treatment unit 600, the ozone is converted into oxygen by the activated carbon and then discharged to the outside B4 .

In the center of the cooling device, a reaction device 500 is installed vertically from the lower surface, and a transparent window is formed in the reaction device 500 to enable observation of reaction between ozone and olive oil.

Meanwhile, it is preferable that the ozone bubble discharge at step s200 is formed into fine ozone bubbles through the bubble discharge port unit 800 and is discharged into the reactor unit 500.

The structure of the bubble discharging unit 800 is summarized as follows.

In other words, a hole 811 for supplying ozone supplied from the ozone supply pipe 330 is formed in the lower part of the bubble discharge device unit. The uppermost discharge hole 812, the middle discharge hole 814, The bubbles discharged from the uppermost discharge hole are discharged horizontally or upwardly (in the F1 direction), and the bubbles discharged from the middle discharge hole 814 are discharged through the central passage 819, (F2 direction) having an angle of 70 degrees to 89 degrees with respect to the horizontal plane through the intermittent discharge hole 814 connected to the discharge port 814 so that the bubble has a strong upward energy. The bubbles discharged to the lower discharge hole 816 are directed in the horizontal or oblique downward direction (F3 direction) and are formed in the forward direction of 360 angles with respect to the central axis to promote mixing with olive oil descending downward do.

FIG. 1 is an overall schematic view of the present invention, FIG. 2 is a photograph of the inside of a cooling apparatus of an actual apparatus of the present invention, FIG. 3 is a view of an oxygen generator and an ozone generator, Fig. 6 is a view for explaining the principle of ozone injection in the multiple bubble jetting apparatus. Fig.

Referring to FIG. 1, there is shown an ointment production apparatus using ozonized oil of the present invention.

The ointment for treating skin diseases according to the present invention mainly comprises an apparatus for generating ozone, an apparatus for bubbling ozone into multiple bubbles, an apparatus for reacting ozone with olive oil in a cooling apparatus, and a ozone treatment apparatus have.

First, an apparatus for generating ozone will be described.

Prior to the generation of ozone, oxygen is first produced from atmospheric air. And then supplied to the ozone generator using the generated oxygen to generate ozone. In FIG. 1, since the oxygen generating apparatus 200 generates oxygen by receiving air in the atmosphere, it is sufficient to use a known technique, so that a detailed description thereof will be omitted.

The generated oxygen is pumped and oxygen is pumped to the cooling unit 100 in the direction A1 along the oxygen supply pipe 210 to cool the pumped oxygen.

The temperature of the cooling unit 100 should be maintained at 3 to 7 degrees Celsius. This is also the temperature required in the reactor unit 500 for ointment production to be described later.

After the cooling pipe 250 through which the oxygen flows is cooled, the cooling water is exhausted from the cooling device 100 (A2, A3) and passed through a water removing unit 280 for removing moisture contained in oxygen cooling. The oxygen (A4) from which moisture has been removed enters the ozone generator 300, and ozone having a concentration of 1700 to 2000 ppm is generated. Of course, the scope of the present invention is not limited to such a specific concentration of ozone.

The generated ozone is introduced into the cooling device unit 100 in the direction of the arrow B1 along the ozone supply pipe 310.

Since moisture is still contained in the ozone, the ozone is subjected to the moisture removing unit 400 for removing the ozone. The removed moisture is discharged to the outside through the water discharge pipe (410).

The ozone with moisture removed flows in the B2 direction along the ozone supply pipe 330 and is supplied through the reactor unit 500.

The reaction apparatus unit 500 is preferably formed as a cylindrical longitudinally elongated cylindrical shape, and a bubble discharge port 800 having a large number of ozone discharge holes is formed at a lower portion thereof.

A detailed description of the bubble discharging unit 800 will be described later with reference to Figs. 5 and 6.

It is preferable that the amount of ozone supplied to the reactor unit 500 be 3 to 6 liters per minute, but this is merely an example, and the size of the reactor unit 500, the amount of the olive oil 700, It is needless to say that it can be added or subtracted in consideration of the internal temperature and the like.

The bubbles supplied into the reactor 500 with fine bubbles react with the olive oil 700 previously supplied to the reactor 500 for 100 to 150 hours. In the apparatus of FIG. 2, the olive oil supplied to the reactor 500 is 2.5 liters, and a minute ozone bubble 900 is supplied for one week to cause a reaction to generate ozonized oil.

When ozone and olive oil are reacted as described above, an ointment, which is ozonated oil in a semi-solid state, is produced and is obtained (C) through the ointment discharge pipe 570.

On the other hand, the ozone which has not been completely reacted in the reactor 500, that is, the ozone is discharged to the ozone treatment unit 600 through the ozone discharge pipe 580 along the direction B3.

Since the ozone itself may be harmful to the human body when the ozone is discharged to the outside, ozone is converted into oxygen and discharged to the outside (B4) by using a known ozone treatment means such as activated carbon in the ozone treatment section.

Through FIGS. 2 to 6, it is possible to grasp the actual appearance of each of the main apparatuses of FIG.

2, the oxygen generator unit 200 and the ozone generator unit 300 are not shown. The oxygen generator unit 200 and the ozone generator unit 300 are the same as the cooling unit 100 of FIG. 3 As shown in Fig.

The cooling device part 100 is maintained at 3 to 7 degrees centigrade and the cooling pipe part 250 for cooling the oxygen generated from the oxygen generating device part 200 is connected to the cooling device part 100, And is formed on the inner side surface.

At the center of the cooling unit, a reaction unit 500 is installed vertically from the lower surface, and a transparent window is formed to enable observation of reaction between ozone and olive oil.

The ozone supplied from the ozone supply pipe 330 is formed into a fine bubble from the lower side to the upper side through the bubble discharging device 800 and is introduced into the reactor 500. As shown in FIG. 6, So that the bubble 900 is multi-directionally injected from the medial center toward the outside.

3 shows an ozone generator 300 attached to a side surface of the cooling device 100 and an oxygen generator 200 installed at a lower portion thereof. It can be seen that a ozone discharge pipe 580 for discharging one ozone is installed.

4, the bubble discharging mechanism 800 will be described with reference to Fig.

A bubble discharging device 800 for supplying ozone bubbles is formed under the reaction device 500. The bubbles are finely supplied in multiple directions to effectively react with the olive oil in the reaction device 500 Is its main function.

Referring to FIG. 6, a hole 811 for receiving ozone supplied from the ozone supply pipe 330 is formed in a lower portion of the bubble discharge device.

The bubble discharging unit 800 is formed so as to have a structure of bubbling minute bubbles and discharging the bubbles in a multi-stage, radial direction (all directions).

The reason for this is that the multi-stage ejection hole is formed by the uppermost ejection hole 812, the middle ejection hole 814, and the lower ejection hole 816 as shown in FIG.

The bubbles discharged in the F3 direction are discharged through the discharge holes directed horizontally or obliquely downward, and are formed in the forward direction of 360 angles with respect to the central axis.

The bubble discharged in the F2 direction is discharged through the stop discharge hole 814 connected to the central passage 819. [ The stop discharge hole is formed so as to have a strong upward energy with the bubble having an angle of 70 to 89 degrees with respect to the horizontal plane.

The bubbles discharged from the uppermost portion are discharged in the F1 direction and discharged horizontally or upward.

In other words, the conventional bubble generator is charged into the fluid only by the buoyancy of the bubble itself. However, the bubble jetting device 800 for discharging the ozone bubble 900 according to the present invention has the bubble jetting device 800, The ozone bubbles are discharged, and therefore, a strong convection phenomenon is continuously formed in the place where the olive oil is located. As a result, the contact frequency of the olive oil and ozone increases, and the ozonized olive oil ointment agent can be generated at a high rate in the low temperature state in the cooling self-heating portion 100.

In the present invention, the olive oil and the ozone bubble 900 are allowed to react in the cooling device unit 100 at a low temperature for 100 to 150 hours, whereby ozonated olive oil ointment having a semi-solid or creamy property can be produced. When the temperature of the cooling unit is higher than the above temperature, the ointment is produced in a state like water having a very low viscosity, not ointment, so that ozone is separated from the olive oil after production and is easily gasified, It becomes difficult to exert its effect. Therefore, the ointment should be prepared according to the temperature, and whether or not the temperature is maintained during the reaction through the normal temperature sensor should be checked.

The ozone-treated olive oil produced in step I is referred to as ozone ointment.

II . Ozone ointment Beta Glucan  And cosmetic preparation step by mixing of hyaluronic acid

 The ozone ointment thus prepared is mixed with beta-glucan and hyaluronic acid to prepare cosmetics.

By mixing the weight of beta-glucan and hyaluronic acid of 0.1 to 0.3% by weight with respect to the ozone ointment weight, the acne treatment and sterilization functions are simultaneously exhibited.

The acidity of beta-glucan and hyaluronic acid should be maintained between 7.2 and 7.4 pH.

Beta Glucan is a kind of polysaccharide that has immune enhancing action and is present in yeast cell walls, mushrooms, cereals, etc. It activates immune function of normal human cells and inhibits proliferation and recurrence of cancer cells, decreases blood sugar and blood cholesterol, Metabolism is improved to inhibit body fat formation and accumulation. Beta Glucan activates the immune function of human normal cells by nonspecific immune response without directly attacking cancer cells. It inhibits the proliferation and recurrence of cancer cells, activates macrophages, enters the body of cancer cells, enters into the body of various cytokines Cytokine secretion by promoting the immune function of the immune function of T cells and B cells is activated. In addition, beta glucan has excellent blood glucose lowering effect and blood cholesterol reducing effect, and has been reported to have an anti-obesity effect by inhibiting body fat formation and accumulation by improving lipid metabolism.

Beta Glucan
Molecular structure

Molecular formula
(C ₁₈ H ₃₀ O ₁₄ ) _n

Hyaluronic acid is generally manufactured and sold as sodium hyaluronate. The properties of sodium hyaluronate are white powder, which is soluble in water and forms jellies or viscous solutions with various viscoelastic properties depending on the molecular weight, concentration, ionic strength, etc. of the hyaluronic acid. Hyaluronic acid is a representative glycosaminoglycan named in 1934 by Meyer et al., Separated from the vitreous of cow. Hyaluronic acid is widely and distributed in the connective tissues of mammals, and is found in many kinds of chicken eggs, skin, skin, aorta and joint fluid. Other microorganisms such as streptococci are also reported to be produced. The safety of purified hyaluronic acid is very safe because it is negative both LD ₅₀ , subacute toxicity, mutagenicity test, eye mucosa stimulation test, skin first stimulation test, cumulative skin irritation test and human patch test. The pharmacological action of hyaluronic acid has been reported to inhibit lymphocyte and macrophage migration.

Hyaluronic acid
Molecular structure

Molecular formula
(C ₁₄ H ₂₁ NO ₁₁ ) _n

Hyaluronic acid is a component of polysaccharides present in the extracellular matrix of almost all tissues and maintains the water content of tissues to maintain extracellular space and promote the transport of electrolytes and nutrients (Meyer LJ and Stern R Dermatol., 102: 385-9, 1994), and is also effective in promoting the migration of fibroblasts and in the deposition of collagen fibers and wound healing. (Doillon CJ and Silver FH, Collagen-based wound dressing: effects of hyaluronic acid and fibronectin on wound healing. Biomaterials, 7: 3 1986). Hyaluronic acid has been adopted as a component of the invention for the manufacture of products for acne and atopic dermatitis and sensitive skin with extended capillary blood vessels and hyaluronic acid has almost the same degree of hygroscopicity and feeling of use under low humidity and high humidity conditions There are also advantages.

Because ozone ointment produces ozone gas and pure olive olive oil only cosmetic products, there is no side effect from steroid series, and it has the advantage of being able to treat acne without worrying about secondary infection due to strong oxidative power and sterilizing power.

100: cooling device unit 200: oxygen generating device unit
210: oxygen supply pipe
250: cooling pipe 280: water removal
300: ozone generator unit
330: Ozone supply pipe
400: water removal unit 410: water discharge pipe
500: Reactor unit 570: Ointment discharge pipe
580: Ozone discharge pipe of the ship
600: boat ozone treatment part 700: olive oil
800: bubble discharge port 819: central conduit 900: ozone bubble

Claims (8)

Generating oxygen and using it to generate ozone (s100);
a step (s200) of bubbling the ozone generated in step 100 into a bubble in the cooling device 100 to perform bubble discharge;
Reacting ozone and olive oil in a cooling device (s300);
The step of treating the ozone after step S300 (S400)
Mixing the ozone-treated olive oil, the betaclucan and the hyaluronic acid with the ozone-treated olive oil so that the weight of each of the beta-glucan and the hyaluronic acid is 0.1 to 0.3% by weight (s1000);
≪ / RTI >

In step s100,
Air is taken in the air to generate oxygen through the oxygen generator unit 200 and then generated oxygen is pumped to flow oxygen A1 along the oxygen supply pipe 210 toward the cooling unit 100 Sending (S110),
(S120) of cooling the oxygen drawn into the cooling pipe 250 in the cooling unit 100 from 3 to 7 degrees Celsius,
A step (s130) of passing through the water removing unit 280 for removing oxygen (A2, A3) from the cooling device unit 100 having the cooling pipe 250 and removing water contained in the oxygen cooling,
And the oxygen (A4) from which moisture has been removed is drawn into the ozone generator 300 to generate ozone at a concentration of 1700 to 2000 ppm (s140)
Beta-glucan and hyaluronic acid have an acidity of 7.2 to 7.4 pH,
Ozone ointment and method of manufacturing cosmetics using beta-glucan and hyaluronic acid
In the method for producing cosmetics by mixing ozone ointment prepared by reacting ozone with olive oil and beta- glucan and hyaluronic acid having an acidity of 7.2 to 7.4 pH,

In order to produce an ozone ointment obtained by reacting the olive oil with ozone,
Generating oxygen and using it to generate ozone (s100);
a step (s200) of bubbling the ozone generated in step 100 into a bubble in the cooling device 100 to perform bubble discharge;
Reacting ozone and olive oil in a cooling device (s300);
and the apparatus (400) for treating ozone remaining unreacted after step s300,
After step s100,
(s210) in which the ozone generated in step s100 is introduced into the cooling device unit 100 along the ozone supply pipe 310,
Removing the water remaining in the ozone through the water removing unit 400 (s220)
(s230) discharging the moisture removed in step S220 to the outside of the cooling apparatus unit 100 through the water discharge pipe 410,
After the ozone with moisture removed flows along the ozone supply pipe 330 and is supplied to the bubble discharge device 800 on the lower side of the reaction device unit 500 in which the ozone and the olive oil are reacted, The step (s300) of mutually reacting the ozone with the olive oil is performed
Ozone ointment and method of manufacturing cosmetics using beta-glucan and hyaluronic acid [4] The apparatus according to claim 2, wherein the reaction device unit (500) comprises a cylindrical
Ozone ointment and method of manufacturing cosmetics using beta-glucan and hyaluronic acid
The ozone generator according to claim 2, wherein the amount of ozone supplied to the reactor unit (500) is 3 to 6 liters per minute,
Ozone ointment and method of manufacturing cosmetics using beta-glucan and hyaluronic acid [3] The ozone bubble generator according to claim 2, wherein the ozone bubble reacts with the olive oil (700) supplied to the reactor unit (500) for 100 to 150 hours
Ozone ointment and method of manufacturing cosmetics using beta-glucan and hyaluronic acid Generating oxygen and using it to generate ozone (s100);
a step (s200) of bubbling the ozone generated in step 100 into a bubble in the cooling device 100 to perform bubble discharge;
Reacting ozone and olive oil in a cooling device (s300);
and the apparatus (400) for treating ozone remaining unreacted after step s300,

(C) through the ointment discharge pipe 570, the ointment which is the semi-solid ozonized oil produced after the step S300,
In step S400,
The ozone, which is ozone which is not completely reacted in the reactor 500,
Is discharged to the ozone treatment unit 600 through the ozone discharge pipe 580,
Wherein the ozone treatment unit converts ozone to oxygen by activated carbon and then discharges the ozone to the outside (B4). The ozone ointment is characterized in that the ozone ointment is mixed at room temperature such that the weight content of hyaluronic acid and beta-glucan is 0.1 to 0.3 wt% In addition,
Beta-glucan and hyaluronic acid each have an acidity of 7.2 to 7.4 pH
Ozone ointment and method of manufacturing cosmetics using beta-glucan and hyaluronic acid
The method according to any one of claims 1 to 6,
The reactor unit 500 is vertically installed at the center of the cooling unit and the reaction unit 500 is provided with ozone ointment in which a transparent window is formed to allow observation of reaction between ozone and olive oil, How to make cosmetics
Generating oxygen and using it to generate ozone (s100);
(s200) of performing ozone bubble ejection by bubbling the ozone generated in step 100 in the cooling apparatus 100;
Reacting ozone and olive oil in a cooling device (s300);
After step S300, the ozone is supplied to the treatment apparatus (s400)
For the olive oil reacted with ozone completed in s300 above,
Mixing 0.1 to 0.3 wt% each of beta-glucan and hyaluronic acid having an acidity of 7.2 to 7.4 at room temperature;
≪ / RTI >

In step s100,
Air is taken in the air to generate oxygen through the oxygen generator unit 200 and then generated oxygen is pumped to flow oxygen A1 along the oxygen supply pipe 210 toward the cooling unit 100 Sending (S110),
(S120) cooling the oxygen drawn into the cooling pipe 250 in the cooling device unit 100 from 3 degrees to 7 degrees Celsius; (S130) through the water removing unit 280 for removing water contained in the oxygen cooling step and the oxygen A4 removed from the water are introduced into the ozone generator 300, And a step (S140) of generating ozone at a concentration of 1700 to 2000 ppm,
Between steps s100 and s300,
a step S210 in which the ozone generated in the step S100 is introduced into the cooling unit 100 along the ozone supply pipe 310 and a step S220 in which moisture remaining in the ozone is removed by passing through the water removal unit 400, (S230) of discharging the moisture removed in the step S220 to the outside of the cooling apparatus unit 100 through the water discharge pipe 410, and a step (S230) of removing the moisture from the ozone supply pipe 330 (S340) of reacting the ozone with the olive oil after passing through a step (s240) of supplying the ozone and the olive oil to the bubble ejection apparatus 800 on the lower side of the reaction apparatus unit 500 in which the ozone and the olive oil react with each other ,
In step S400,
The ozone, which is ozone which is not completely reacted in the reactor 500,
Is discharged to the ozone treatment unit 600 through the ozone discharge pipe 580,
The ozone treatment unit converts ozone into oxygen by activated carbon and discharges the ozone to the outside (B4)
The ozone bubble ejection in step s200 is formed into fine ozone bubbles through the bubble ejection unit 800 and is discharged into the reactor unit 500,
The structure of the bubble discharging unit 800 is,
A bubble discharging device part is provided at its lower part with a hole 811 for receiving ozone supplied from the ozone supply pipe 330. The bubble discharging device 800 has a top discharge hole 812, an intermediate discharge hole 814, The bubbles discharged from the uppermost discharge hole are discharged horizontally or upwardly (in the F1 direction), and the bubbles discharged from the middle discharge hole 814 are discharged through the central passage 819 (F2 direction) having an angle of 70 degrees to 89 degrees with respect to the horizontal plane through the intermittent discharge hole 814 connected thereto, so that the bubble has a strong upward energy,
The bubbles discharged to the lower discharge hole 816 are directed in the horizontal or oblique downward direction (F3 direction) and are formed in the forward direction of 360 angles with respect to the central axis to promote mixing with olive oil descending downward doing
Ozone ointment and method of manufacturing cosmetics using beta-glucan and hyaluronic acid

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