KR20150045571A - Device of centrifugal separation for image capturing of portable syringe - Google Patents

Abstract

According to the present invention, an image-obtaining centrifugal separator of a portable syringe comprises: a rotor having the syringe containing an obtained specimen, and centrifugally separating the specimen when rotated at a high speed; a screen installed on the lower side of the rotor, and having a penetration hole; and a photographing part photographing the stop motion of the syringe using a camera by emitting an instantaneous light through a flash unit on the lower side of the screen when the syringe rotated at a high speed passes by the penetration hole.

Description

TECHNICAL FIELD [0001] The present invention relates to an image acquisition centrifugal separator for a mobile syringe,

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an image acquisition centrifugal separator for a mobile syringe, and more particularly, to an image acquisition centrifugal separator for a mobile syringe which is capable of capturing still images during centrifugation of a sample obtained from a living body, And to an acquisition centrifuge device.

Fat transplantation is not just the use of fat from fat as in the past, but the process of separating living fat cells through centrifugation and washing.

Unlike the oil from the destroyed fat cells and the blood from the inhalation cause the necrosis of the implanted adipose tissue, it is essential to improve the survival rate dramatically by introducing a technique for separating only living adipocytes.

In this procedure, a small incision is made in the body part, and a tube with a hole at the end (liposuction tube) is inserted, and the fat is sucked out by using the sound pressure of the syringe.

Then, liquid components such as adipose stem cells, red blood cells, blood and water were separated into layers from the fat collected in the syringe through a centrifugal separator, and then the free oil, which was separated from the layered red blood cells and broken fat cells in the syringe free oil and the like, and only the adipose stem cells to be transplanted are taken and injected into the human body.

In order to achieve this, the fat syringe is transferred to a test tube for centrifugation at a positive pressure. Then, the test tube is attached to a centrifuge and rotated at a high speed to separate the fat substances according to the particle size and density, (Red blood cells, free oil).

Here, centrifugation utilizes the density difference between the solid and the liquid surrounding the solid. By putting some of the mixed material in the test tube and turning it quickly, it gives artificially strong acceleration, so that the heavy material sinks under the test tube and the light material floats on top.

That is, as shown in FIG. 1, as shown in FIG. 1, the inhaled fat is centrifuged, and erythrocytes E are located at the lowest layer in the test tube, free oil F is located at the uppermost layer, Adipose stem cell S is divided into layers.

Then, only the adipose stem cells S are extracted from the test tube through the syringe equipped with the needle.

However, in the case of the conventional technique, the internal state of the syringe rotating at high speed during the centrifugal separation process can not be visually confirmed, and the centrifugation process is determined according to the skill of the medical person.

As a result, the cells of the sample may be damaged when the centrifugation is performed excessively.

Also, in order to reduce errors in the centrifugal separation, it is necessary to switch the high-speed rotation state of the centrifuge to the off state and then check the centrifugal separation state. In the course of repeating the centrifugal separation state, .

Therefore, in order to solve the above-described problems, the image acquisition centrifuge of the mobile syringe of the present invention enables the imaging of the syringe at high speed during the centrifugation of the sample so that the process of centrifugation can be visually confirmed I have to.

In order to accomplish the above object, the present invention provides an image acquisition centrifugal separator for a mobile syringe, comprising: a rotor for centrifugally separating a sample by mounting a syringe containing the sample at a high rotation speed; And a photographing unit for photographing a syringe through a camera to emit an instantaneous light through a flashing unit at the time the syringe is positioned and acquire an image of a centrifugal separation process of the syringe.

 The image acquisition centrifuge of the mobile syringe of the present invention comprises a rotor for mounting a syringe containing a sample and centrifuging the sample at a high rotation speed, a photographing unit for photographing the syringe and acquiring an image of a centrifugal separation process of the syringe, A syringe which is positioned between the rotor and the photographing unit and has a penetrating hole formed thereon, so that the syringe having either a natural light or an artificial light when the syringe rotates at a high speed is rotated and the syringe rotating at high speed coincides with the position of the photographing range An instantaneous lighting environment is created, and a syringe, which is confirmed through a transmission hole, is photographed through a camera of the photographing unit to acquire an image of a centrifugal separation process of the syringe.

According to the present invention, the rotor is configured such that the connecting shaft vertically coupled to the center is axially coupled to the rotating shaft of the motor.

According to the present invention, the rotor is configured such that the connecting shaft vertically coupled to the center is axially coupled to the rotating shaft of the motor.

According to the present invention, the first sensor is installed on the rotary shaft so that the first sensor is rotated, and the second sensor senses the rotating first light.

According to the present invention, the rotor is provided with a coupling space formed to be equally divided on the outer periphery, and a bucket is rotatably coupled to the coupling space, thereby mounting the syringe on the bucket.

According to the present invention, the syringe is made of a transparent material.

According to the present invention, the curtain film is made of a material which does not transmit light.

According to the present invention, the image acquired through the photographing unit is displayed on an external screen.

As described above, the image acquisition centrifugal separator of the mobile syringe of the present invention includes a rotor for centrifugally separating a sample by mounting a syringe containing a sample and rotating the syringe at a high speed, and a syringe And a photographing unit for photographing a syringe through a camera to emit an instantaneous light through a flashing unit at a time point and acquiring an image of a centrifugal separation process of the syringe to photograph an image of the syringe having high- So that it is possible to visually check the centrifugal separation process of the centrifugal separator.

FIG. 1 is a perspective view showing a state in which centrifuged fat cells according to the prior art form an interlayer structure in a test tube. FIG.
2 is an exploded perspective view showing a first embodiment of an image acquisition centrifugal separator for a mobile syringe of the present invention.
3 is an exploded perspective view of a first embodiment of the image acquisition centrifuge of the mobile syringe of the present invention.
4 is an overall sectional view showing a first embodiment of the image acquisition centrifugal separator of the mobile syringe of the present invention.
5 is a partially enlarged cross-sectional view showing a first embodiment of an image acquisition centrifuge of the mobile syringe of the present invention.
6 is an operating state sectional view showing a first embodiment of an image acquisition centrifuge of the mobile syringe of the present invention.
7 is an exploded perspective view showing a second embodiment of the image acquisition centrifugal separator of the mobile syringe of the present invention.
FIG. 8 is a perspective view showing a second embodiment of the image acquisition centrifuge of the mobile syringe of the present invention. FIG.
9 is an overall sectional view showing a second embodiment of the image acquisition centrifuge device of the mobile syringe of the present invention.
10 is a partially enlarged cross-sectional view showing a second embodiment of the image acquisition centrifuge of the mobile syringe of the present invention.
11 is an operating state sectional view showing a second embodiment of the image acquisition centrifuge of the mobile syringe of the present invention.
12 is an operating state sectional view showing another embodiment of the second embodiment of the image acquisition centrifuge of the mobile syringe of the present invention.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, the present invention will be described in detail with reference to the accompanying drawings. First, it should be noted that, in the drawings, the same components or parts have the same reference numerals as much as possible. In the following description of the present invention, a detailed description of known functions and configurations incorporated herein will be omitted so as to avoid obscuring the subject matter of the present invention.

FIG. 2 is an exploded perspective view showing a first embodiment of the image acquisition centrifuge of the mobile syringe of the present invention, FIG. 3 is an assembled perspective view showing the first embodiment of the image acquisition centrifuge of the mobile syringe of the present invention, FIG. 4 is an overall sectional view showing the first embodiment of the image acquisition centrifuge of the mobile syringe of the present invention, and FIG. 5 is a partially enlarged sectional view showing the first embodiment of the image acquisition centrifuge of the mobile syringe of the present invention And FIG. 6 is an operating state sectional view showing the first embodiment of the image acquisition centrifuge of the mobile syringe of the present invention, and FIG. 7 is an exploded perspective view showing the second embodiment of the image acquisition centrifuge of the mobile syringe of the present invention FIG. 8 is a perspective view showing a second embodiment of the image acquisition centrifuge of the mobile syringe of the present invention. FIG. 9 is a perspective view showing the image acquisition centrifuge of the mobile syringe of the present invention 10 is a partially enlarged cross-sectional view showing a second embodiment of the image acquisition centrifuge device of the mobile syringe of the present invention, and Fig. 11 is a partial enlarged cross-sectional view of the image acquisition centrifugal device of the mobile syringe of the present invention 12 is an operating state sectional view showing another embodiment of the second embodiment of the image acquisition centrifuge of the mobile type syringe of the present invention.

Hereinafter, the present invention refers to a sample obtained from a living body as a fat, and the type of the tissue is exemplified by fat tissue, blood, bone marrow, muscle, skin, liver, connective tissue, fascia and other soft liquid tissues or tissue components And it is not limited to them, but also chemical substances other than biological materials are applicable.

The liposuction material used in the present specification means all the materials that are generated when liposuction is carried out. Typically, such liposuction materials include aspirates by adipose tissue and liposuction.

In the stem cell separation according to the present invention, the starting material (hereinafter referred to as a " sample ") must first be obtained. The sample can be obtained as fat through liposuction.

The fat may be a human fat, and it may be a fat when it is cultured with adipose-derived stem cells and used for molding purposes. On the other hand, liposuction can be performed at a desired treatment site, and fat can be collected through a syringe.

Herein, the injector which can be used includes all types capable of collecting fat, and as a non-limiting example, Korean Patent Application Nos. 2003-5029, 2005-61134, 2005-34848, 2006-64946, Korean Utility Model Application Nos. 2003-21484, 2004-10685, 2006-26454.

The feature of the injector is that the liposuction material sucked at the same time as the liposuction is blocked from the atmosphere.

As is well known, the syringe is comprised of a needle and a syringe 10, a piston, and a rod, and the syringe applied in the present invention is configured such that the piston and the rod, which generate pressure inside the syringe 10, can be selectively separated or combined.

Here, the syringe 10 is formed with a flange at the opposite end of the tip, and the infiltration means can be applied as a needle or a tube (liposuction tube).

Especially. The syringe 10 applied to the present invention is made of a transparent material so that a sample contained in the syringe 10 can be visually confirmed from the outside.

The syringe 10 obtained as described above is mounted on a centrifuge 100 capable of image capturing, and centrifugal separation is performed.

The centrifugal separator 100 is provided with a motor 103 for generating a high rotational force, and a main body 101 having a rotating shaft 104 of the motor 103 and a space therein.

Various devices for performing a centrifugal separation function are mounted on the main body 101, and a lid 105 is hingedly connected to the upper part of the main body 101. In particular, a liquid crystal screen 102 is provided on the entire surface of the main body 101, and a centrifuged image of the syringe 10 to be described later can be displayed on the screen.

The liquid crystal screen 102 may be displayed on an external screen other than the main body.

In addition, the opened upper portion of the main body 101 can be opened and closed through the cover 105.

A motor 103 is mounted on the lower portion of the main body 101, and a rotating shaft 104 of the motor 103 is exposed to the inside of the main body.

The main body 101 thus provided is provided with a device for acquiring a video image of the state of centrifugal separation.

2 to 6, the centrifugal separator 100 capable of image capturing according to the first embodiment includes a rotor 110 and a photographing unit 130.

The rotor 110 is mounted with a syringe 10 containing a sample, and the sample is centrifuged at high speed.

When the syringe 10 is positioned within the shooting range of the camera 132 when the syringe 10 rotates at a high speed, the photographing unit 130 emits an instantaneous light through the scintillating unit 131, photographs the syringe 10 through the camera 132, The image of the separation process is acquired.

The camera 132 may be installed on the bottom surface of the main body 101, or may be installed on a wall or a cover of the inner space of the main body 101. [

The inner space of the main body 101 may be made of a mirror so that the reflection efficiency of the scintillating means 131 can be improved.

Particularly, the rotor 110 is located in the inner space of the main body 101 and can be separated from the rotation axis 104 of the motor 103, and can be selectively axially coupled.

The rotor 110 is formed in the shape of a circular plate and has a half-groove engagement space 111 equally divided at the outer periphery thereof. The bucket 112 having an annular shape is rotatably coupled to the engagement space 111.

In the bucket 112 of the rotor 110 configured as described above, the syringe 10 from which the sample is extracted can be mounted, and the flange of the syringe 10 is hooked to the upper end of the bucket 112 to maintain the mounted state.

In the center of the rotor 110, a rotating shaft 104 of the motor 103 and a connecting shaft 113 which is connected to the shaft are vertically installed to rotate the rotor 110 at a high speed through the motor 103. At this time, the syringe 10 rotating at high speed is mounted on the bucket 112 by centrifugal force Centrifuge the sample while rotating horizontally.

The photographing unit 130 radiates instantaneous light through the scintillating unit 131, emits an instantaneous light at a time when the syringe 10 rotating at high speed is positioned in the photographing range of the camera 132, 132 to obtain an image.

Here, the scintillation means 131 is a device capable of emitting strong strobe light. That is, the strobe unit 131 applies a strobo.

The instantaneous light of the scintillating means 131 referred to in the present invention refers to light in which strong strobe light is repeatedly generated in a short time of lighting and flashing, and continuous light is light in which lighting is continuously maintained without blinking.

The scintillating means 131 is characterized in that the flashing time is very short, the fast movement is instantaneously captured, and the photographing by the color film is suitable because the light has the same nature as the sunlight. Further, since the light is continuously emitted, the shutter chances of the camera 132 can be captured.

A more important feature of the scintillation means 131 is that it is capable of capturing high-speed motion with an instantaneous light, so that a moment in motion that can not be clearly observed with the naked eye can be stopped and a picture photographed through the camera 132 can be obtained.

That is, when the syringe is positioned at the focus of the camera lens, the camera radiates light through the scintillation means and repeats the step of photographing the image, so that the centrifugation process of the sample can be acquired as an image in the syringe.

At this time, a function for causing light to emit at a time point when the camera focus and the syringe position coincide is configured as follows.

A first sensor 114 is installed on the rotating shaft 104 of the motor 103 and a second sensor 115 recognizing the first sensor 114 is installed in the vicinity of the first sensor 114 to rotate the rotor 110 through the rotating force of the motor 103, The flashing unit 131 irradiates instant light at a time point when the sensor 114 rotates and detects the second sensor 115, thereby creating an environment in which the syringe image can be acquired through the camera.

Here, the first sensor coupled to the rotating shaft 104 and the syringe to be photographed coupled to the rotor 110 are vertically divided. However, since the positions of the first sensor 115 and the second sensor 115 are the same, So that the syringe can be photographed at a high speed by rotating the syringe at the same time as the camera focus.

As shown in Figs. 7 to 12, the second embodiment of the image acquisition centrifuge of the mobile syringe is as follows.

A rotor 110 for mounting a syringe 10 containing a sample and centrifugally separating the sample by high speed rotation; a photographing section 130 for photographing the syringe 10 to acquire an image of a centrifugal separation process of the syringe 10; The syringe is rotated at a high speed to rotate the syringe so that the syringe has natural light or artificial light. When the syringe is rotated at high speed, A syringe which is confirmed through a transmission hole is photographed through a camera of the photographing section to acquire an image of a centrifugal separation process of the syringe.

The rotor has the same configuration and function as the rotor of the first embodiment.

The photographing unit 130 has an illumination environment through natural light or artificial light.

That is, in the case of artificial light, a scintillation means 131 may be provided inside the body 101 to continuously emit continuous light.

In the case of natural light, the cover 105 is opened in the main body 101 to introduce natural light into the inner space of the main body 101 in which the rotor 110 is installed.

A shielding film 120 is provided under the rotor 110.

More specifically, the curtain 120 is positioned below the rotor 110, passes through the connection shaft 113, and rotates integrally with the rotor 110.

In addition, the curtain 120 separates the inner space of the main body 101 while blocking the transmission of light. That is, the artificial light or natural light is transmitted through the curtain 120 only to the light transmitting hole 121.

As a result, when the syringe 10 and the curtain 120 rotate together, the camera 132 photographs the syringe 10 rotating at a high speed and transmits the curtain 120 through the curtain 120 At the time when the ball 121 coincides with the camera position, natural light or artificial light is illuminated by the camera and has an illumination environment with flash.

Thus, an illumination environment having an instantaneous light is created through the screening film 120 to capture a high-speed motion, so that a moment in the motion that can not be clearly observed with the naked eye can be stopped to obtain a picture photographed through the camera 132.

That is, when the syringe is positioned at the focus of the camera lens, the camera 132 emits the light through the scintillation unit 131, and the camera 132 repeats the image capturing process to acquire the centrifugal separation process of the sample in the syringe 10 as an image .

As a result, the image acquisition centrifuge of the mobile syringe of the present invention is capable of imaging an image of the syringe 10 at a high speed, by illuminating the light at the time when the camera 132 focus and the syringe 10 are aligned, It is possible to photograph the high-speed motion during the centrifugal separation of the obtained sample, and to visually confirm the progress of the centrifugal separation, thereby making it possible to reduce errors in the centrifugal separation.

It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit or scope of the inventions. It will be clear to those who have knowledge of.

10: Syringe 100: Centrifuge
101: main body 102: liquid crystal display
103: motor 104:
105: cover 110: rotor
111: coupling space 112: bucket
113: connecting shaft 114: first sensor
115: second sensor 120: shielding film
121: Through hole 130:
131: scintillation means 132: camera
E: red blood cell S: adipose stem cell
F: Free oil

Claims (10)

A rotor mounted on a syringe containing the sample to centrifugate the sample at a high speed,
And a photographing unit for photographing a syringe through a camera to emit an instantaneous light through a scintillating unit at a time when the syringe is positioned within the photographing range of the camera when the syringe rotates at a high speed, Image acquisition centrifuge for mobile syringe.
A rotor mounted on a syringe containing the sample to centrifugate the sample at a high speed,
A photographing section for photographing the syringe and acquiring an image of a centrifugal separation process of the syringe;
And a shielding film which is positioned between the rotor and the photographing portion and has a penetrating hole formed therein
An illumination environment of any one of natural light and artificial light at high speed rotation of the syringe is provided and an instant lighting environment is created when the syringe which rotates at a high speed coincides with the position of the transmission range and the photographing range of the camera, And an image of the centrifugal separation process of the syringe is acquired by photographing the syringe to be inspected. The method according to claim 1,
Wherein the rotor is configured such that a connecting shaft vertically coupled to the center is axially coupled to a rotating shaft of the motor.
3. The method of claim 2,
Wherein the rotor is configured such that a connecting shaft vertically coupled to the center is axially coupled to a rotating shaft of the motor.
3. The method of claim 2,
Wherein the photographing unit is equipped with a scintillation means in the photographing unit when the photographing unit is an illumination environment of artificial light. The method of claim 3,
Wherein the first sensor is installed on the rotary shaft so that the first sensor is interlocked with the first sensor, and the second sensor senses the rotating first sensor to emit the illumination of the scintillation means.
3. The method according to claim 1 or 2,
The rotor may include:
Wherein a coupling space formed to be equally divided is formed on an outer periphery of the bucket, and a bucket is rotatably coupled to the coupling space to mount the syringe on the bucket.
3. The method according to claim 1 or 2,
Wherein the syringe is made of a transparent material.
3. The method according to claim 1 or 2,
Wherein the curtain film is made of a material that does not transmit light.
3. The method according to claim 1 or 2,
And the image acquired through the photographing unit is displayed on an external screen.

Images