KR20140139903A - antimicrobial brush composition having organic nano clay and antimicrobial brush for toothbrush and manufacturing method thereof - Google Patents

Abstract

The present invention relates to an antimicrobial toothbrush composition including organic nanoclay, antimicrobial toothbrushes using the same, and a method for manufacturing the same and, more specifically, to a toothbrush composition which can enhance antimicrobial and washing properties using the organic nanoclay, antimicrobial toothbrushes using the same, and a method for manufacturing the same. The toothbrush composition including the organic nanoclay of the present invention has antimicrobial activities by including synthetic resins and the organic nanoclay. Also, the method for manufacturing the antimicrobial toothbrushes comprises a building step which makes the toothbrush composition by adding the organic nanoclay to the synthetic resins and mixing the same; and a molding step which forms the antimicrobial toothbrushes by molding the toothbrush composition.

Description

TECHNICAL FIELD The present invention relates to an antibacterial bristle composition containing an organic nano-clay, an antibacterial brush bristle using the antibacterial brush bristle, and an antibacterial brush bristle using the antibacterial brush bristle and an antimicrobial brush for toothbrush and manufacturing method,

The present invention relates to an antibacterial bristle composition containing an organic nano-clay, an antibacterial bristle using the antibacterial brush bristle, and a method of manufacturing the same. More particularly, the present invention relates to a brush bristle composition capable of improving antibacterial properties and cleaning power by using an organic nano- Bristles and a method for manufacturing the bristles.

Generally, a toothbrush comprises a bristle, a head having the bristle, and a handle connected to the head. Toothbrushes are an important tool for oral hygiene and should always be clean, especially in the bristles area.

However, in reality, the food residue remains around the bristles even after being washed. Since the bristles are always kept completely dry and are kept in a humid condition, various sanitary problems may occur due to the propagation of the germs.

Therefore, various bristle disinfection methods are used to solve these problems. Several methods have been proposed, including chemical disinfection, ultraviolet disinfection using light irradiation, and disinfection using a sterilizer, but they are not the ultimate solution due to economic inefficiency and difficult portability.

In recent years, methods have been developed in which materials having antimicrobial properties are coated on or mixed with bristles. There is a problem that antibiotic-containing bristles may cause side effects due to overuse of antibiotics.

Korean Patent Registration No. 10-1176036 discloses a bristle composition having an antibacterial activity. However, such conventional techniques have a problem that the antibacterial property is insignificant or the nonuniform mixing phenomenon occurs during the mixing and coating process or the coating peels off. In addition, the conventional technique has a problem that the washing power is weak even if it has antibacterial power.

In order to improve the cleaning effect when brushing teeth, conventional methods for imparting a uniform shape to the surface of the bristles by using a bristle (a usual fine grain) in which a portion of the bristle yarn is used in an aqueous alkaline solution, have. However, such bristles may have various foreign matters remaining in the bristles, which may cause hygiene and cause problems caused by bacterial propagation.

Therefore, the present inventors have repeatedly studied a method for manufacturing a bristle to give an effect of improving cleaning power by changing the surface of bristles while having excellent antimicrobial effect. Using organic clay, the present inventors have found that, besides the excellent antibacterial effect, And the present invention has been completed.

Accordingly, it is an object of the present invention to provide a brush bristle composition capable of improving antibacterial properties and cleaning power by using an organic nano-clay, an antibacterial bristle using the brush bristle, and a method for manufacturing the same.

In order to accomplish the above object, the present invention provides an antibacterial brush bristle composition comprising an organic nano-clay, which comprises a synthetic resin and an organic nano-clay and has antimicrobial activity.

The synthetic resin is at least one selected from the group consisting of polypropylene, polybutylene terephthalate, polytrimethylene terephthalate, and nylon.

The organic nano-clay is contained in an amount of 0.2 to 0.5% by weight in the entire composition.

Wherein the organic nanoclay comprises Mg-APTES / PTES clay.

The Mg-APTES / PTES is a hybrid in which Mg-APTES and Mg-PTES are mixed and immobilized as a cationic metal through a sol-gel reaction, and the cationic metal is Mg ^{2 +} , Ca ²⁺ , ^{Zn 2 +, Mn 2 +,} Cu 2 +, and the ^{Co 2 +, Ni 2 +,} Al 3 + and Fe ^{+ 3} wherein any one selected from.

The antibacterial bristles of the present invention for achieving the above object are characterized by being formed by molding the antibacterial bristle composition.

Wherein the bristles are formed with corrugated irregularities on the surface of the bristles.

In order to accomplish the above object, there is provided a method of manufacturing an antibacterial brush bristle according to the present invention, comprising: preparing a brush bristle composition by adding organic nano-clay to a synthetic resin; And shaping the bristle composition to form an antibacterial bristle.

The antimicrobial brush bristle composition of the present invention is excellent in antibacterial effect against Escherichia coli and Staphylococcus aureus and can effectively prevent the bacteria from living on the surface of the bristles. Therefore, it is possible to prevent inflammation, cavities and bad breath caused by various bacteria in the oral cavity.

In addition, the present invention has an excellent bend recovery rate, and can form a large number of corrugated irregularities on the surface of the bristles, so that it is possible to wipe the corners of the teeth more cleanly when brushing teeth, thereby improving the relief and reducing the widening of the bristles.

Figs. 1A to 1D are diagrams showing the results of experiments using Escherichia The minimum inhibitory concentration (MIC) of the organic nano-clay with respect to E. coli was 1,000 ppm,
Figures 2a-2d are Staphylococcus aureus (Staphylococcus a photograph showing that aureus) Minimum inhibitory concentration (MIC) is 1,000 ppm of organic nanoclay for,
Fig. 3 (c) shows the remaining viable cell counts for Escherichia coli of Comparative Example 2 containing the organic antibacterial agent, Fig. 3 (c) shows the number of viable cells remaining for Escherichia coli containing the organic antibacterial agent, 3H is a photograph showing the number of viable bacteria remaining in E. coli of a bristle containing 0.1%, 0.2%, 0.3%, 0.4% and 0.5% of the organic nano-clay according to Examples 1 to 5.
Fig. 4A shows the number of remaining viable cells of the staphylococci after the culture, Fig. 4B shows the number of remaining viable cells against the staphylococci in the comparative example 1, Fig. 4C shows the number of viable cells in the staphylococcus in the comparative example 2 containing the organic antibacterial agent, Figs. 4D to 4H are photographs showing the number of remaining viable cells of Staphylococcus aureus containing 0.1%, 0.2%, 0.3%, 0.4% and 0.5% of the organic nano-clay according to Examples 1 to 5.
Fig. 5A shows the surface of the PBT bristles of Comparative Example 3, Fig. 5B shows the surface of the bristles of Comparative Example 4 containing the organic antibacterial agent, Figs. 5C to 5G show the results of molding the organic nano- 0.1%, 0.2%, 0.3%, 0.4% and 0.5% of the surface of the bristles were observed with an electron microscope.
Figure 6 relates to a library for the synthesis of organic / inorganic hybrid multifunctional organic nano-clays.
7 is a schematic diagram showing an ideal structure of a synthesized magnesium organophyllosilicate. (B), APTES / TTMS / PTES, (a) Representative structure in the case of using only one of APTES / TTMS / PTES and one of APTES / TTMS / PTES and MTES / (C) Representative structure of mutual combination of PTES.
Fig. 8 is a scanning electron micrograph (c, d) in which Mg-APTES clay is dispersed in water, (a, b), Mg-APTES clay is dispersed in ethanol, Electron microscope photograph (e, f).
9 is an electron micrograph (a, b) of Mg-APTES / PTES (9: 1) dispersed in ethanol and an electron micrograph (c, d) of Mg-APTES / PTES (5: , And an electron microscope (e, f) of Mg-APTES / PTES (1: 9) dispersed in ethanol.

BEST MODE FOR CARRYING OUT THE INVENTION Hereinafter, an antibacterial brush bristle composition containing an organic nano-clay according to a preferred embodiment of the present invention, an antibacterial bristle using the same, and a method for producing the same will be described in detail.

The antimicrobial brush bristle composition according to an embodiment of the present invention includes synthetic resin and organic nano-clay, and has excellent antimicrobial activity. For example, the antimicrobial brush bristle composition may be composed of 99.5 to 99.8% by weight of a synthetic resin and 0.2 to 0.5% by weight of an organic nano-clay.

The synthetic resin may be at least one selected from the group consisting of polypropylene, polybutylene terephthalate, polytrimethylene terephthalate, and nylon.

The content of the organic nano-clay is preferably 0.2 to 0.5% by weight, and it has been experimentally confirmed that moldability and antibacterial activity are excellent within this range.

The nano-clay known as an organic nano-clay that can be applied to the present invention may be used, but it includes a preferable Mg-APTES / PTES clay having excellent thermal stability with an organic nano-clay.

These organic nanoclays are hybrid claws which are composed of an organosilane having an amino group and an organosilane having other functional groups (-SH, Phenyl, OH etc.).

Mg-APTES / PTES clay is a hybrid in which Mg-APTES and Mg-PTES are mixed and immobilized with a cationic metal. The mixing is such that the molar ratio of Mg-APTES: Mg-PTES is 9: 1 to 1: 9. The mixing may be performed in any organic solvent selected from the group consisting of ethanol, methanol, dimethylformamide (DMF), and dimethyl sulfoxide (DMSO).

And APTES is any one selected from the group consisting of (3-aminopropyl) triethoxysilane, 3- (2-aminoethylamino) propyl] trimethoxysilane and 3- [2- (2-aminoethylamino) ethylamino] propyltrimethoxysilane.

And PTES means phenyltriethoxysilane.

And one which the cationic metal is selected from ^{Mg 2 +, Ca 2 +,} Zn 2 +, Mn 2 +, Cu 2 +, Co 2 +, Ni 2 +, Al 3 + and Fe ^3+.

Figure 6 shows a library for the synthesis of hybrid clay. 6, the organosilane series in the cyclic direction in which basic organoclay can be synthesized and the cationic metal in the column direction are summarized. This is about organoclay synthesis in which one organosilane is immobilized through a sol-gel reaction to one central ion (cationic metal). In particular, the first column is the aminosilane-based organosilane, which does not require a catalyst when synthesizing clay. However, the hybrid clay focuses on oil-inorganic clay synthesized by mixing two or more organosilanes, and this table corresponds to the basic framework for this. Of course, two or more cationic metals may also be used herein.

And FIG. 7 is a schematic diagram of an ideal structure of a synthesized magnesium organophyllosilicate. (B), APTES / TTMS / PTES, (a) Representative structure in the case of using only one of APTES / TTMS / PTES and one of APTES / TTMS / PTES and MTES / The representative structure of the combination of PTES is (c). 7, when a species of organosilane is used, each of -NH ₂ , -SH, and -Phenyl extends in the side direction, and a clay having a very high density of functional groups is produced. However, when they are mixed with the case of TEOS (functional group constituted by OH groups), they act as crosslinking between the clay sheet structures and prevent clay from being dispersed by peeling. It acts as a kind of defect and induces the structure of clay. However, when two or more APTES / TTMS / PTES are mixed, the functional group protrudes in the side direction randomly. In this case, the decrease of the dispersion degree in the aqueous solution is considered to be due to the fact that TTMS and PTES have a role of crosslinking in the clay sheet The dispersity in the aqueous solution tends to decrease due to the decrease of -NH ₂ site.

The bristle composition of the present invention containing the above-described organic nano-clay can be formed into a bristle by drawing with an extruder.

When the organic nano-clay is added to the synthetic resin and mixed, it is preferable that the mixed materials are uniformly mixed so that they do not clump together and are not shifted to one side. More preferably, a blender can be used, have.

The method of spinning the bristles, which are chemical fibers, from the bristle composition to which the organic nano-clay is added to the synthetic resin can be carried out by a conventional method known in the art. In this method, a synthetic resin is prepared by master batch, A method in which nano-clay is mixed and then radiated, or a method in which an organic nano-clay is added to a synthetic resin, followed by performing a master batch to pelletize the mixture, followed by melt spinning.

The master batch is prepared by mixing a resin serving as a main raw material with an additive for imparting functionality and then rotating the mixture by a mixer and then extruding the raw material by a twin screw extruder having an appropriate temperature to produce pellets The term "melt spinning" as used herein refers to a method in which fibers having a fiber forming ability are heated and melted and then pushed into air or gas or appropriately cooled and solidified into a liquid to produce fibers.

Once the bristles are formed, they can be cut and processed in a conventional manner to prepare the bristles to be implanted in the toothbrush.

The toothbrush comprises a body composed of a head part and a handle, and bristles bristled on the head part.

The body can typically be molded according to a method of manufacturing a toothbrush, i. E. By injection of a synthetic resin into a mold and injection molding. The synthetic resin may be any synthetic resin used in toothbrush manufacturing. Examples of the synthetic resin include polypropylene (PP), polyester (PS), silicone, polyvinyl chloride (PVC), polycarbonate (PC) PE), polystyrene, acylonitrile, polyethylene terephthalate (PBT), polyphenylene oxide, polyurethane (PU), nylon, acid polyethylene terephthalate glycol (acid PETG), styrene acrylonitrile resin (SAN) Hexylene dimethylene terephthalate (PCTA) and rubber, or a combination of two or more thereof.

When the head portion and the handle of the toothbrush are manufactured as described above, it is possible to provide a toothbrush that can improve the antibacterial and cleaning power by putting the bristles on the head portion of the toothbrush.

Hereinafter, the content of the present invention will be described in detail through Production Examples, Experimental Examples and Examples. It should be understood, however, that these examples are provided for illustrative purposes only and are not to be construed as limiting the scope of the present invention.

<Production example of organic nanoclay>

For the preparation of Mg-APTES clay, dissolve 4.06 g of MgCl ₂ .6H ₂ O in 40 mL of ethanol, add 6.22 mL of APTES (3-aminopropyltriethoxysilane), add 5 mL of NaOH (1.0 N or 5.0 N) The reaction was allowed to proceed for a period of time.

For the preparation of Mg-PTES clay, dissolve 4.06 g of MgCl ₂ .6H ₂ O in 40 mL of ethanol, add 6.42 mL of PTES (phenyltriethoxysilane), mix 5 mL of NaOH (1.0 N or 5.0 N) The reaction was allowed to proceed for a period of time.

For the preparation of the hybrid type Mg-APTES / PTES clay, 4.06 g of MgCl ₂ .6H ₂ O was dissolved in 40 mL of ethanol. APTES (3-aminopropyltriethoxysilane) was added first according to the desired molar ratio and then PTES phenyltriethoxysilane) according to the molar ratio. Next, 5 mL of NaOH (1.0 N or 5.0 N) was added, and the reaction was allowed to proceed for 48 hours.

FIG. 6 is a scanning electron micrograph (c, d) in which Mg-APTES clay is dispersed in water, (a, b), Mg-APTES clay is dispersed in ethanol, Electron microscope photograph (e, f). In particular, Mg-APTES clay shows a lamellar morphology and has a submicro-size distribution of about 30-100 nm. The scanning electron microscope photograph shows a microscopic pattern like a brick, Although the laminate structure can not be confirmed, it seems that the laminate structure can be confirmed clearly in the aqueous liquid phase. In the case of Mg-PTES, small bead-like grains are gathered, and it is predicted that the powder shape is smaller than that of Mg-APTES.

7 is an electron micrograph (a, b) of Mg-APTES / PTES (9: 1) dispersed in ethanol and an electron micrograph (c, d) of Mg-APTES / PTES (5: , And an electron microscope (e, f) of Mg-APTES / PTES (1: 9) dispersed in ethanol. Specifically, in the case of a hybrid clay (Mg-APTES / PTES clay), it is characterized by a smooth surface such as a jelly. Especially, 1: 9 image with relatively high PTES has mostly granular shape, which is similar to Mg-PTES clay image.

<Experimental Example 1> Measurement of the minimum inhibitory concentration (MIC) of the nano-clay solution against E. coli

The purified water was added to the Mg-APTES / PTES nano-clay prepared in the above Preparation Example to obtain 250ppm nano clay solution, 500ppm nano clay solution and 1,000ppm nano clay solution, respectively.

E. coli, which is a reference material under the conditions shown in the following Table 1, was inoculated into the LB medium in the above 250 ppm nano clay solution, 500 ppm nano clay solution and 1,000 ppm nano clay solution, and then the cell concentration was measured by liquid culture, Mu] l of each well and cultured for 24 hours. The minimum inhibitory concentration of the nano-clay against E. coli was measured using a cell concentration measurement method and a viable cell count method, and it is shown in Table 1 and Figs. 1a to 1d below.

FIG. 1B is a photograph showing the number of viable cells obtained by applying the reference material Escherichia coli to a solid medium after liquid culture and FIG. 1B is a photograph showing the number of viable cells after liquid culture of Escherichia coli as a reference material in a 250ppm nano clay solution 1C is a photograph showing the number of viable cells by applying a standard culture medium of Escherichia coli to a 500 ppm nano clay solution and then applying the solution to a solid medium. FIG. 1D is a photograph of the Escherichia coli as a reference material in a 1,000 ppm nano- This is a photograph showing the viable cell count by applying to a solid medium.

The minimum inhibitory concentration of the nanoclay solution for E. coli was found to be 1,000 ppm through the following Table 1 and FIGS. 1A to 1D.

Item Reference substance Nano clay solution
1,000ppm Nano clay solution
500ppm Nano clay solution
250ppm Cell concentration 1.209 0.071 0.361 1.028 Number of living cells (CFU / ml) ^{1 )} 1.50 x 10 ⁷ <10 0.75 x 10 ⁷ 1.00 x 10 ⁷ Antimicrobial activity (%) ^{2 )} - 99.9 50.0 33.3 MIC 1,000 ppm

¹⁾ number of viable cells N = C × D × V, [C: number of colonies (per one specimen), D: dilution ratio (dilution ratio of dilution), V: in the medium used for inoculum recovered liquid volume (㎖)]

²⁾ Antimicrobial activity = {(AB) / A} 100, (A: the number of viable cells remaining in the control group, B:

<Experimental Example 2> Measurement of minimum inhibitory concentration (MIC) for staphylococci in a nano-clay solution

The purified water was added to the Mg-APTES / PTES nano-clay prepared in the above Preparation Example to obtain 250ppm nano clay solution, 500ppm nano clay solution and 1,000ppm nano clay solution, respectively.

Staphylococci as reference substances under the conditions shown in the following Table 2 were inoculated into the TSB medium in the above 250 ppm nano clay solution, 500 ppm nano clay solution and 1,000 ppm nano clay solution, and then the cell concentration was measured by liquid culture, And cultured for 24 hours. The minimum inhibitory concentration of the nano-clay against Staphylococcus aureus was measured using a cell concentration measurement method and a viable cell count method, which are shown in the following Table 2 and Figs. 2 (a) to 2 (d).

FIG. 2A is a photograph showing the number of viable cells obtained by applying the reference material Staphylococci as a liquid to the solid medium, and FIG. 2B is a photograph showing the number of live cells FIG. 2C is a photograph showing the viable cell count by applying the reference material Staphylococcus aureus as a reference material to a solid medium after liquid culture in a 500ppm nano clay solution, and FIG. 2D is a photograph showing the staphylococcus as a reference material in a 1,000ppm nano- After liquid culture, it was applied to a solid medium to show viable cell count.

The minimum inhibitory concentration of the nanoclay solution for Staphylococcus aureus was found to be 1,000 ppm through the following Table 2 and FIGS. 2 (a) to 2 (d).

Item Reference substance Nano clay solution
1,000ppm Nano clay solution
500ppm Nano clay solution
250ppm Cell concentration 1.453 0.129 0.499 1.389 Number of living cells (CFU / ml) ^{1 )} 1.50 x 10 ⁷ <10 0.75 x 10 ⁷ 1.25 x 10 ⁷ Antimicrobial activity (%) ^{2 )} - 99.9 50.0 16.7 MIC 1,000 ppm

¹⁾ number of viable cells N = C × D × V, [C: number of colonies (per one specimen), D: dilution ratio (dilution ratio of dilution), V: in the medium used for inoculum recovered liquid volume (㎖)]

²⁾ Antimicrobial activity = {(AB) / A} 100, (A: the number of viable cells remaining in the control group, B:

&Lt; Examples 1 to 5 >

To 10 kg of polybutylene terephthalate (PBT) as a resin raw material of the bristles, the Mg-APTES / PTES nano-clay prepared in the above preparation example was added and mixed for 10 minutes. Then, a PBT masterbatch was obtained through a twin screw extruder M / B).

The resulting PBT masterbatch was spun to produce a bristles having a nano-clay content of 0.1 to 0.5 wt% in a polybutylene terephthalate (PBT) resin. The spinning conditions were such that the temperature of the extruder was maintained at 250 占 폚, the residence time of 5 minutes, the stirring speed of 35 rpm, the cooling temperature of 24 占 폚 and the heating temperature of 85 占 폚.

The prepared bristles are summarized in Table 3 according to the content of the nano-clay.

division Example 1 Example 2 Example 3 Example 4 Example 5 Nano clay content (wt.%)
0.1%
0.2%
0.3%
0.4%
0.5%

<Experimental Example 3> Radioactive evaluation of bristles

The degree of drawing (spinning) of the bristles according to the content of the nano-clay in the production of the bristles of Examples 1 to 5 was tested. The radioactive evaluation method was carried out according to the criteria described below, and the results are shown in Table 4.

- Radioactive evaluation standard

◎: continuous radiation for 60 minutes or more,

○: continuous radiation for 10 minutes or more,

[Delta]: continuously irradiated for 1 minute or more,

X: continuously radiated for less than 1 minute,

division Example
One Example
2 Example
3 Example
4 Example
5 Of each bristle
Radioactive evaluation
◎
◎
◎
◎
○

As shown in Table 4, when the bristles containing 0.1, 0.2, 0.3 and 0.4% of the nano-clay of the present invention were produced (Example 1, Example 2, Example 3, Example 4) Continuous spinning was possible, and it was found that continuous spinning was possible from 10 minutes to less than 60 minutes when the bristles containing 0.5% nano-clay were prepared (Example 5).

<Experimental Example 4> Evaluation of antimicrobial properties of bristles

(Example 1, Example 2, Example 3, Example 4) obtained by allowing continuous spinning for more than 60 minutes among the bristles manufactured above to evaluate antibacterial properties of the bristles manufactured according to the method of the present invention, and 10 (Example 5) was measured for antibacterial activity against Escherichia coli and Staphylococcus aureus by the method of KS J 4206; 2008, which is a method for evaluating antimicrobial activity of common bristles.

For this, both microbial culture medium (LB medium for E. coli, TSB medium for Staphylococcus aureus) and 50 ml tubes and bristles were sterilized under pressure steam. After adding 1.0 g of each bristle to the sterilized tube, 25 ml of the sterilized microorganism medium was added, and the mixture was liquid shaken at 37 DEG C and 150 rpm for 24 hours. Liquid shaken samples were inoculated with 50 占 퐇 of each strain of 1.0 占⁰³ CFU / ml and cultured with shaking at 37 占 폚 and 150 rpm for 24 hours. Each culture medium was applied to a solid medium in an amount of 20 μl, and cultured at 37 ° C for 24 hours. The viable cell count was counted to measure the antibacterial activity. At this time, as a control group, only a 1.0 × 10 ³ CFU / ml strain was inoculated and cultured without the addition of a bristle material. As a comparative group, antibacterial activity was measured using the PBT bristles (Comparative Example 1) and nano silver-containing bristles (Naosilver, PEDEX, Germany) (Comparative Example 2) most commonly used as bristles.

The antimicrobial activity of each of the bristles measured according to the above experiment was evaluated according to the criteria described below. The results are shown in Table 5, and shown in FIG. 3 and FIG. 4. FIGS. 3A to 3H are photographs showing the viable cell counts of the respective bristles with respect to the coliform bacteria, and FIGS. 4A to 4H are photographs showing the viable cell counts of the respective bristles with respect to the staphylococci.

There is a significant increase in the number of bacteria in the control group cultured for 24 hours after the inoculation than the initial number of bacteria in the control group after the inoculation, thereby establishing the conditions for the test establishment. A pronounced increase means that the growth value of the bacteria must exceed 31.6 times, otherwise the test is deemed invalid and a retest is performed. Here, the proliferation value is a value obtained by dividing the number of bacteria (average value) of the control group by the initial number of bacteria (average value) of the control group after culturing for 24 hours.

When the test is valid, the rate of bacterial reduction by the test groups (comparative examples and examples) is calculated to evaluate the antimicrobial activity. Here, the microbial reduction rate (%) is {(M _b -M _c ) / M _b } × 100, M _b is the number of bacteria in the control group after 24 hours of incubation and M _c is the number of bacteria (Average value).

division Comparative Example
One Comparative Example
2 Example
One Example
2 Example
3 Example
4 Example
5 Of each bristle
Reduction rate (%) for E. coli
0
37.5
0
25.0
37.5
87.5
98.3 Of each bristle
Reduction rate for staphylococci (%)
0
50.0
0
25.0
50.0
62.5
8.8

As a result of the antibacterial test, as shown in Table 5, the bristles of Examples 4 and 5 containing nano-clay at 0.4% and 0.5% were PBT bristles (Comparative Example 1) and bristles containing organic antibacterial agents (Comparative Example 2 ) Than the control group.

Experimental Example 5 Evaluation of Flexural Recovery Rate of Bristles

In order to evaluate the bending recovery rate of the bristles, it was possible to continuously spin for more than 60 minutes among the bristles manufactured above, and the bristles (Example 1, Example 2, Example 3, and Example 4) (Example 5) was measured by the method of KS G 3103; 2003, which is a method of measuring the simulated bending recovery rate. The flexion recovery rate of the bristles carried out by the above method was evaluated according to the criteria described below, and the results are shown in Table 6.

- Evaluation criteria of flexion recovery rate

A: Excellent recovery rate of 50% or more,

○: The flexural recovery value was good at 26 to 49%

X: The bending recovery value is less than 25%, which can not be used as a bristle.

division Comparative Example
One Comparative Example
2 Example
One Example
2 Example
3 Example
4 Example
5 Of each bristle
Flexion recovery rate 36 ~ 39
? 37.5 36 ~ 39
? 37.5 36 ~ 39
? 37.5 39 to 42
40.5 39 to 42
40.5 42 to 45
43.5 42 to 45
43.5

As shown in Table 6 above, the brush bristles containing nano-clay at 0.1%, 0.2%, 0.3%, 0.4% and 0.5% (Example 1, Example 2, Example 3, Example 4, Example 5 ), General PBT bristles (Comparative Example 1), and bristles containing an organic antibacterial agent (Comparative Example 2) were found to be in the range of 26 to 49% in terms of the valley recovery rate. (Comparative Example 1) and bristles containing an organic antimicrobial agent (Comparative Example 2) were obtained in the same manner as in Example 1, except that the brush bristles (Example 3, Example 4, Example 5) containing nano- clay at 0.3%, 0.4% Of the bristles were 3.0 to 5.0% better than the bristles. As a result, it can be seen that the present invention has a better bending recovery rate than conventional bristles containing PBT and organic antimicrobial agents.

Experimental Example 6 Evaluation of surface roughness of bristles

(Example 1, Example 2, Example 3, Example 4) obtained by allowing continuous spinning for more than 60 minutes among the bristles manufactured in the above to evaluate the cleaning effect at the time of brushing of the bristles, The surface of the obtained bristles (Example 5) capable of spinning was observed using an electron microscope, respectively, and the results are shown in Table 7 below.

- Evaluation criteria of surface roughness of bristles

&Amp; cir &amp;: The surface of the bristles was observed to be very wrinkled,

A: The surface of the bristles was partially wrinkled,

X: The surface of the bristles was smoothly observed,

division Comparative Example
One Comparative Example
2 Example
One Example
2 Example
3 Example
4 Example
5 Of each bristle
Surface observation
×
×
◎
◎
◎
◎
◎

As shown in Table 7, the degree of corrugation of the surface of the bristles analyzed using the electron microscope was not observed at all in the case of the bristles containing the general PBT bristles and the organic antibacterial agent (see FIGS. 5A and 5B). On the other hand, in the case of Examples 1, 2, 3, 4 and 5, in which the nano-clay was contained at 0.1%, 0.2%, 0.3%, 0.4% and 0.5% (Fig. 5C to Fig. 5H).

It can be seen from the above experiments that the present invention is superior to the conventional bristles containing PBT bristles and organic antibacterial agents. Since the present invention can effectively prevent the formation of various bacterium species living on the surface of the bristles, it is expected that inflammation, cavities and bad breath caused by various bacteria in the oral cavity can be prevented. In addition, unlike the conventional bristles, the present invention is capable of forming a large number of corrugated irregularities on the surface of the bristles to greatly enhance the cleaning effect when brushing teeth.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be clearly understood that the same is by way of illustration and example only and is not to be taken by way of limitation. Accordingly, the true scope of protection of the present invention should be determined only by the appended claims.

Claims (8)

An antimicrobial brush bristle composition containing an organic nano-clay, which comprises a synthetic resin and an organic nano-clay and has antimicrobial activity. The method according to claim 1, wherein the synthetic resin is at least one selected from the group consisting of polypropylene, polybutylene terephthalate, polytrimethylene terephthalate, and nylon An antibacterial brush head composition comprising an organic nanoclay. The antimicrobial brush bristle composition according to claim 1, wherein the organic nano-clay is contained in an amount of 0.2 to 0.5% by weight in the entire composition. The antimicrobial brush bristle composition of claim 1, wherein the organic nanoclay comprises Mg-APTES / PTES clay. 5. The method of claim 4, wherein the Mg-APTES / PTES is a hybrid in which Mg-APTES and Mg-PTES are mixed and immobilized with a cationic metal,
The cationic metal is ^{Mg 2 +, Ca 2 +,} Zn 2 +, Mn 2 +, Cu 2 +, Co 2 +, Ni 2 +, Al 3 + , and an organic, characterized in that any one selected from Fe ^{3 +} An antibacterial bristle composition comprising a nanoclay. An antimicrobial bristle formed by molding the antimicrobial bristle composition of any one of claims 1 to 5. The antimicrobial brush head according to claim 6, wherein the bristles are formed with corrugated irregularities on the surface of the bristles. A composition step of adding an organic nano-clay to a synthetic resin and then mixing to form a bristle composition;
And forming the bristle composition to form antibacterial bristles. &Lt; Desc / Clms Page number 20 &gt;

Images