KR20140129164A - 히스톤 데아세틸라아제 억제제 및 파조파닙의 조합물 및 이의 용도 - Google Patents
히스톤 데아세틸라아제 억제제 및 파조파닙의 조합물 및 이의 용도 Download PDFInfo
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- KR20140129164A KR20140129164A KR1020147025547A KR20147025547A KR20140129164A KR 20140129164 A KR20140129164 A KR 20140129164A KR 1020147025547 A KR1020147025547 A KR 1020147025547A KR 20147025547 A KR20147025547 A KR 20147025547A KR 20140129164 A KR20140129164 A KR 20140129164A
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- salt
- abecinostat
- cancer
- pazopanib
- hcl
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- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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Landscapes
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- Veterinary Medicine (AREA)
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| US61/602,544 | 2012-02-23 | ||
| PCT/US2013/026462 WO2013123413A2 (en) | 2012-02-17 | 2013-02-15 | Combinations of histone deacetylase inhibitor and pazopanib and uses thereof |
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| EP (1) | EP2814493A4 (enExample) |
| JP (1) | JP2015507020A (enExample) |
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| AU (1) | AU2013221298A1 (enExample) |
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| RU (1) | RU2014137190A (enExample) |
| SG (1) | SG11201404888SA (enExample) |
| WO (1) | WO2013123413A2 (enExample) |
Cited By (1)
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| WO2015088847A1 (en) * | 2013-12-11 | 2015-06-18 | Glaxosmithkline Llc | Treating cancer with a combination of a pd-1 antagonist and a vegfr inhibitor |
| EP3325623B3 (en) * | 2015-07-23 | 2021-01-20 | Institut Curie | Use of a combination of dbait molecule and parp inhibitors to treat cancer |
| WO2017053823A1 (en) * | 2015-09-25 | 2017-03-30 | Pharmacyclics Llc | Treatment using hdac inhibitors and immunotherapy |
| CA3060509A1 (en) * | 2017-04-21 | 2018-10-25 | Federica Sotgia | Targeting hypoxic cancer stem cells (cscs) with doxycycline: implications for improving anti-angiogenic therapy |
| JP7227777B2 (ja) * | 2019-02-04 | 2023-02-22 | キヤノン株式会社 | 撮像装置 |
| WO2022125551A1 (en) * | 2020-12-07 | 2022-06-16 | Hht Foundation International, Inc. | Method of treating hereditary hemorrhagic telangiectasia using pazopanib |
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| HRP20090487T1 (hr) * | 2003-04-07 | 2009-12-31 | Pharmacyclics | Hidroksamati kao terapeutski agensi |
| EP1755394A4 (en) * | 2004-04-16 | 2009-08-05 | Smithkline Beecham Corp | METHOD OF TREATING CANCER |
| SI1954281T1 (sl) * | 2005-11-29 | 2011-06-30 | Glaxosmithkline Llc | Postopek zdravljenja raka |
| EA201170821A1 (ru) * | 2008-12-15 | 2011-12-30 | Эли Лилли Энд Компани | Энзастаурин для лечения рака |
| US8603521B2 (en) * | 2009-04-17 | 2013-12-10 | Pharmacyclics, Inc. | Formulations of histone deacetylase inhibitor and uses thereof |
| TW201206908A (en) * | 2010-05-05 | 2012-02-16 | Glaxo Wellcome Mfg Pte Ltd | Pharmaceutical compositions and methods of making same |
| WO2012103276A1 (en) * | 2011-01-26 | 2012-08-02 | Glaxo Wellcome Manufacturing Pte Ltd | Combinations |
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| KR20220018727A (ko) | 2020-08-07 | 2022-02-15 | 계명대학교 산학협력단 | 파조파닙 또는 이의 약학적으로 허용가능한 염을 유효성분으로 함유하는 비만 예방 또는 치료용 조성물 |
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| CN104244952A (zh) | 2014-12-24 |
| EP2814493A4 (en) | 2015-07-22 |
| EP2814493A2 (en) | 2014-12-24 |
| HK1204998A1 (en) | 2015-12-11 |
| WO2013123413A2 (en) | 2013-08-22 |
| JP2015507020A (ja) | 2015-03-05 |
| SG11201404888SA (en) | 2014-09-26 |
| CA2864736A1 (en) | 2013-08-22 |
| AU2013221298A1 (en) | 2014-08-28 |
| US20150335609A1 (en) | 2015-11-26 |
| RU2014137190A (ru) | 2016-04-10 |
| MX2014009892A (es) | 2015-02-12 |
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