KR20140102489A - Monitoring apparatus and method of sclerosis of the blood vessels based on oscillometric arterial blood pressure measurement - Google Patents

Abstract

The present invention relates to a device and a method for measuring angiosclerosis based on oscillometric arterial blood pressure measurement. The device according to an embodiment of the present invention comprises the following: a pressure detection sensor unit to detect a cuff pressure including the influence of a pulse wave; a pulse wave extracting unit to extract the pulse wave signals of arteries from the cuff pressure detected by the pressure detection sensor unit; a pulse wave amplitude detecting unit to divide the pulse wave signals extracted by the pulse wave extracting unit into multiple window sections, and detect a minimum amplitude value of a first window section and a minimum amplitude value of a second window section in the window sections; and an angiosclerosis analyzing unit to analyze the degree of angiosclerosis using the minimum amplitude values of the first and second window sections detected by the pulse wave amplitude detecting unit, thereby allowing an individual to simply examine the degree of angiosclerosis of arteries in the hospital or at home, etc. without help of an expert.

Description

TECHNICAL FIELD [0001] The present invention relates to an apparatus and a method for measuring blood vessel hardening based on an oscillometric metastatic arterial blood pressure measurement,

The present invention relates to an apparatus and a method for measuring blood vessel hardening based on an oscillometric arterial blood pressure measurement, and more particularly, to an apparatus and method for measuring a blood vessel hardening based on an oscillometric arterial blood pressure measurement, The present invention relates to an apparatus and a method for measuring blood vessel hardening based on measurement of an oscillometric metastatic arterial blood pressure.

Atherosclerosis is a phenomenon in which blood vessels are narrowed and blood vessels are narrowed and arterial walls are hardened by depositing fat, cholesterol, abnormal tissues, etc. on the walls of the blood vessels and causing dangerous complications such as cerebral infarction, angina pectoris, myocardial infarction, peripheral vascular occlusion and renal sclerosis do. Early detection and management of these arteriosclerosis can prevent complications and usually screen risk factors for arteriosclerosis by measuring blood pressure, cholesterol testing, and diabetes testing. These tests, however, do not show the degree of elasticity of the actual artery, only the factors that cause arteriosclerosis.

On the other hand, Pulse Wave Velocity can measure the elasticity of the blood vessels and the degree of precipitation of the inner wall of the blood vessels, thereby measuring atherosclerosis indicating how hard the blood vessels are, and screening for arteriosclerosis early. The currently used atherosclerotic test method generates pressure waves on the aorta during cardiac contraction, and this pressure wave is transmitted to the peripheral artery along the aorta. The pressure waves reaching the peripheral artery are marked by the difference in arrival time according to the distance from the heart to the distal artery, and the distance traveled by this pressure wave divided by the difference in time of arrival.

The problem with measuring atherosclerosis is the measurement of the exact distance at which the pulse wave is delivered. The exact distance measurement of the pulse wave is problematic because of the difference in body fatness and flexion. In patients with atherosclerosis or congenital aortic flexion, The actual distance that the pulse wave travels is long, and the atherosclerosis test value is measured to be small. In addition, if the recorded pulse wave is not clear without understanding the principle of the atherosclerosis method, the time difference between pulse waves can not be accurately measured and a wrong value may be obtained. Therefore, users who use these arteriosclerosis tests should always establish a standardized environment and regularly train them.

In order to solve the above-mentioned problems, the present invention provides a method of analyzing a blood pressure pattern of a pulse wave signal generated by using a cuff pressure on a cuff or a wrist for about one minute to measure the degree of decrease of elasticity by hardening of an artery, It is an object of the present invention to provide an apparatus and a method for measuring blood vessel hardening based on blood pressure measurement.

The present invention also provides an apparatus and method for measuring blood vessel hardening based on an oscillometric meta-arterial blood pressure measurement for measuring vascular hardening using minimum amplitude values detected from a pulse wave signal corresponding to a first section and a second section of a plurality of window sections The purpose is to provide.

According to an aspect of the present invention, there is provided an apparatus for measuring blood vessel hardening based on an oscillometric meta arterial blood pressure measurement, including: a pressure detecting sensor unit for detecting a cuff pressure including an influence of a pulse wave; A pulse wave extracting unit for extracting a pulse wave signal of an artery from the cuff pressure detected by the pulse wave detecting unit in the pulse wave detecting unit; A pulse wave amplitude detection unit for detecting a minimum amplitude value of the first window interval and a minimum amplitude value of the second window interval; and a blood vessel hardening analysis unit for analyzing the blood vessel hardening degree using the minimum amplitude value of the first window interval and the minimum amplitude value of the second window interval, Provide wealth.

 The vascularization analyzer analyzes the degree of vascularization using the difference between the minimum amplitude value of the first window section and the minimum amplitude value of the second window section detected by the pulse wave amplitude detection section.

 The apparatus for measuring blood vessel hardening based on the measurement of an oscillometric arterial blood pressure further includes a pulse wave signal normalizing unit for generating a normalized pulse wave signal by using a plurality of pulse wave signals extracted from the same pulse wave measuring unit and outputting the pulse wave signal to a pulse wave amplitude detecting unit The pulse wave amplitude detecting section divides the normalized pulse wave signal output from the pulse wave signal normalizing section into a plurality of window sections and detects a minimum amplitude value of the first window section and a minimum amplitude value of the second window section of the plurality of window sections can do.

 It is preferable that the pulse-wave-signal normalizing unit normalizes the plurality of pulse-wave signals extracted from the pulse-wave extracting unit by squaring each of the plurality of pulse-wave signals and using a root value of the sum.

 The vascular cure analyzing unit analyzes the difference value obtained by subtracting the minimum amplitude value of the first window section from the minimum amplitude value of the second window section detected by the pulse wave amplitude detecting section as a positive value and a higher value as a value of atherosclerosis is higher, The smaller the value, the lower the arteriosclerosis is preferably analyzed.

 The pulse wave amplitude detection unit detects a minimum amplitude value in each window section of a plurality of windows and the apparatus for measuring blood vessel hardening based on the measurement of the oscillometric metastatic arterial blood pressure detects a hypertension using the minimum amplitude value in each window section detected by the pulse wave amplitude detection unit And a personal characteristics analyzing unit for analyzing personal characteristics using the degree of vascularization analyzed in the vascularization analyzing unit.

 The number of windows dividing the pulse wave signal extracted from the pulse wave extraction section into a plurality of window sections can be obtained based on the number of minimum vibration waveforms and the number of pulse vibration waveforms including one pulse of the maximum period.

A method for measuring vascular cirrhosis based on measurement of an oscillometric metastatic arterial blood pressure according to the present invention includes the steps of detecting a cuff pressure including an influence of a pulse wave from a cuff wound on an arm or a cuff of a subject, Dividing the extracted pulse wave signal into a plurality of window sections, detecting a minimum amplitude value of the first window section and a minimum amplitude value of the second window section of the plurality of window sections, The above-mentioned object can be achieved by providing a step of analyzing the degree of vascularization using the minimum amplitude value of the interval and the minimum amplitude value of the second window interval.

 The step of analyzing the individual characteristics can analyze individual characteristics by averaging the minimum amplitude values in each window section obtained for each subject for each window section.

With the above-described configurations, the present invention can easily examine the degree of hardening of an artery in a hospital or a home without the help of an expert.

FIG. 1 is a view illustrating an apparatus for measuring blood vessel hardening based on measurement of an oscillometric metastatic arterial blood pressure according to an embodiment of the present invention.
2 is a flowchart showing a method for measuring vascular hardening based on the measurement of the oscillometric metastatic arterial blood pressure shown in Fig.
FIG. 3 is a chart recording data measured five times for a plurality of subjects.
Fig. 4 is a view showing a pressure signal of the cuff shown in Fig. 1. Fig.
5 is a view showing a pulse wave signal extracted by the pulse wave extraction unit shown in FIG.
6 is a diagram showing a minimum amplitude value in one window section.
7 is a diagram showing the minimum amplitude value detected in each window of the same subject and the minimum amplitude value detected in each window using the normalized pulse wave signal.
8 is a graph showing an arterial hardening degree using a difference value between minimum amplitude values of a first window section and a second window section of a normalized pulse wave signal.
9 to 11 are diagrams showing the average distribution of atherosclerosis according to the classification of hypertension, pseudohypertension, and normal blood pressure from 85 Canadian people aged 20 to 80 years.
12 to 14 illustrate the distribution of hypertension, physiological hypertension, and normal blood pressure from the data of 180 Korean Koreans aged 20 to 80 years at the time of comprehensive health screening, and show an average distribution of atherosclerosis according to the classification FIG.
FIG. 15 is a view illustrating an apparatus for measuring blood vessel hardening based on measurement of an oscillometric metastatic arterial blood pressure according to another embodiment of the present invention.
16 is a flowchart showing a method for measuring vascular hardening based on the measurement of the oscillometric metastatic arterial blood pressure shown in Fig.
FIG. 17 is a diagram showing a personal characteristic pattern belonging to the hypertensive group of systolic blood pressure among the subjects shown in FIG. 3; FIG.
FIG. 18 is a view showing a personal characteristic pattern belonging to a normal group of systolic blood pressure among the subjects shown in FIG. 3; FIG.
FIG. 19 is a graph showing the minimum amplitude value in each window section of a subject who is a '47-year-old Korean male, belonging to a hypertensive group of 140/80 mmHg and' obese '.
20 is a 23-year-old Korean male showing a minimum amplitude value in each window section of a subject in the hypertensive group of 144/81 mmHg.

Hereinafter, an apparatus and method for measuring blood vessel hardening based on measurement of an oscillometric metastatic arterial blood pressure according to an embodiment of the present invention will be described in detail with reference to the accompanying drawings.

FIG. 1 is a view illustrating an apparatus for measuring blood vessel hardening based on measurement of an oscillometric metastatic arterial blood pressure according to an embodiment of the present invention.

The heart pushes blood along the arteries every time it pulses, and this flow of blood causes the arteries to swell and relax, which is called pulse. An oscillometric method, which is one of the methods for measuring blood pressure, generally measures the blood pressure of an arm or the like in a linear or stepwise manner at the time of cardiac contraction and cardiac expansion, extracts a pulse wave signal from the measured pressure, The blood pressure (systolic blood pressure) and the minimum blood pressure (diastolic blood pressure) are obtained.

1, an apparatus 100 for measuring blood vessel hardening based on an oscillometric metastatic arterial blood pressure measurement includes a cuff 110, a pressure detecting sensor unit 120, a pulse wave extracting unit 130, a pulse wave signal normalizing unit 140, A pulse wave amplitude detector 150, a blood vessel cure analyzer 160, a storage unit 170, and a display unit 180.

The cuff 110 is wrapped around a measurement site when measuring blood pressure and is wound around an arm or a cuff and connected to a pressurizing pump (not shown) and an exhaust valve (not shown) through an internal pipe (not shown) do.

The pressure detecting sensor unit 120 is connected to the cuff 110 through an internal pipe to detect a cuff pressure including an influence of a pulse wave, that is, a pressure of the cuff 110.

The pulse-wave extraction unit 130 extracts a pulse wave signal of an artery of the entire section from the cuff pressure detected by the pressure detection sensor unit 120. On the other hand, when a plurality of pulse wave signals are to be obtained from the same subject for normalizing the pulse wave signal, the pulse wave signal extracted by the pulse wave extraction unit 130 is stored in the pulse wave signal storage region of the storage unit 170.

The pulse-wave-signal normalization unit 140 normalizes a plurality of pulse-wave signals extracted from the pulse-wave extraction unit 130 obtained from the same subject, in order to reduce a change in the pulse- ) To output a normalized pulse wave signal of the subject.

The pulse wave amplitude detector 150 divides the pulse wave signal inputted to the pulse wave extractor 130 or the normalized pulse wave signal of the subject into a plurality of window sections and outputs a minimum amplitude value MIAP (Minimum Amplitude Pulse) .

The vascularization analyzer 160 analyzes the degree of vascularization using the minimum amplitude values of the first window interval and the second window interval detected by the pulse wave amplitude detector 150.

The storage unit 170 may be used to obtain a plurality of pulse wave signals from the same subject for normalizing the pulse wave signal. In this case, the pulse wave signal extracted by the pulse wave extraction unit 130 is stored in the pulse wave signal storage area of the storage unit 170.

The display unit 180 may display information on the degree of vascularization, etc., analyzed by the vascularization analyzer 160.

1 may be implemented by a single device such as a blood pressure monitor or the like. The blood pressure monitor 100 may include a cuff 110, a pressure detection sensor unit 120, And a computer / monitor including the pulse wave signal normalization unit 140, the pulse wave amplitude detection unit 150, the vascularization analysis unit 160, the storage unit 170, and the display unit 180.

FIG. 2 is a flow chart showing a method for measuring vascular hardening based on the measurement of an oscillometric meta-arterial blood pressure shown in FIG. 1, FIG. 3 is a chart recording data measured five times for a plurality of subjects, FIG. 5 is a view showing pulse wave signals extracted by the pulse wave extracting unit shown in FIG. 1, and FIG. 6 is a diagram showing pulse wave signals extracted from a minimum amplitude value 7 is a diagram showing a minimum amplitude value detected in each window using a minimum amplitude value and a normalized pulse wave signal detected in each window of the same measurer, FIG. 5 is a graph showing an arteriosclerosis using a difference value between minimum amplitude values of a first window section and a second window section.

Hereinafter, a method of analyzing the degree of vascularization based on the measurement of the oscillometric metastatic arterial blood pressure according to the flowchart shown in FIG. 2 will be described.

When the cuff 110 is wound around a human arm or a cuff, and the vascular cure measuring apparatus 100 is operated to measure blood pressure, the cuff pressure is detected through the pressure detecting sensor unit 120 (S202). The cuff pressure signal detected by the pressure detection sensor unit 120 is shown in Fig.

The cuff pressure detected by the pressure detection sensor unit 120 is extracted from the pulse wave signal of the artery of the entire section by the pulse wave extraction unit 130 (S204). The pulse wave signal extracted by the pulse wave extracting unit 130 is shown in FIG. This pulse wave signal can be extracted by using the difference information of the cuff pressure sequentially input from the pressure detection sensor unit 120 and by removing the influence of the average decompression amount of the cuff pressure included in the difference information.

The pulse wave signal extracted by the pulse wave extraction unit 120 may be stored in the storage unit 170 until a plurality of pulse wave signals are obtained from the same subject (S206). Data measured five times for each subject are shown in FIG.

That is, the number of vibration waveforms of the pulse wave signal and the pulse wave signal extracted from the cuff pressure is stored in the storage unit 170, and the age and sex of the subject and the maximum blood pressure (systolic blood pressure) measured by the nurse through the stethoscope and the minimum Blood pressure (diastolic blood pressure) can be stored. The pulse wave signal extracted from the pulse wave extracting unit 130, the pulse wave signal extracted from the cuff pressure, and the maximum blood pressure and the minimum blood pressure measured through the stethoscope are stored in a plurality of times Section 170 of FIG.

In FIG. 3, it can be seen that the number of vibration waveforms measured five times in the same subjects is similar. This means that the same subject has a similar-sized pulse wave signal.

When the number of times of measurement for the same subject reaches N times, the pulse-wave-signal normalization unit 140 performs normalization to reduce a change in the pulse-wave signals showing a change for each measurement count of the same subject (S208 ). That is, a plurality of pulse wave signals for the same subject stored in the storage unit 170 are normalized to obtain data showing that the personal characteristics can be more accurately analyzed based on the oscillometric arterial blood pressure measurement.

The normalization in the pulse-wave-signal normalization unit 140 can normalize the pulse-wave signal corresponding to the subject based on the following equation (1).

를 얻을 수 있다. 그리고 동일한 피측정자로부터 얻어진 맥파 신호들은

로 표현될 수 있으며, 맥파 신호(W_ij)는 i번째 피측정자의 j번째 맥파 신호를 의미한다.First, the total number of obtained data (60 in FIG. 3) is denoted by W, the number of subjects (shown in FIG. 3 as 12 persons) is denoted by N,

Can be obtained. And the pulse wave signals obtained from the same subject

And the pulse wave signal W _ij means the jth pulse wave signal of the i-th subject.

는 동일한 피측정자의 맥파 신호들을 각각 제곱하여 더한 값을 루트화한 값이다. 그리고 정규화된 맥파 신호 Wi^*는 피측정자의 맥파 신호들을 맥파 크기값

로 나눈 정규화된 맥파 신호들이다.Here, the same pulse wave amplitude value

Is a value obtained by rooting a value obtained by squaring the pulse wave signals of the same subject. The normalized pulse wave signal Wi ^* is obtained by multiplying the pulse wave signals of the subject by the pulse wave amplitude value

Which are normalized pulse wave signals.

The pulse wave amplitude detector 150 divides the whole interval of the normalized pulse wave signal obtained by the pulse wave signal normalization unit 140 into a plurality of window intervals (S210). In this case, the number of feature windows is based on the minimum number of vibration waveforms of the normalized pulse wave signal of each subject (the minimum number of vibration waveforms in case of the subject S1 in Fig. 3 is 9004) and the number of vibration waveforms in which one pulse is generated Respectively. In addition, in order to compare the characteristics of the mapping window of the subject to be analyzed, it is preferable that all the normalized pulse wave signals are divided into the same number of windows.

The number of feature windows (FW) can be determined by two parameters. If the minimum number of vibration waveforms is? And the number of pulse vibration waveforms including one pulse in the maximum period is?, The number of feature windows FW can be calculated by the following equation (2).

In the present invention, the entire duration of the normalized pulse wave pattern obtained by the pulse wave signal normalization unit 140 is divided into 29 window sections using Equation (2).

The pulse-wave amplitude detector 150 detects a minimum amplitude value in each of the plurality of window sections (S212). The respective minimum amplitude values in one window section are shown in FIG. The uppermost region of the pulse wave signal shown in FIG. 6 is the maximum amplitude value, and the region at the lowermost end indicates the minimum amplitude value. Therefore, at least one pulse wave signal should be included in one window section. If there are a plurality of pulse wave signals in one window section, the smallest value is the minimum amplitude value. Here, the minimum amplitude value is detected. However, the maximum amplitude value or the average amplitude value (MAP) obtained by averaging the amplitude values of one window section according to the personal characteristics to be analyzed, as well as the individual characteristics are grasped only by the minimum amplitude value, Mean Amplitude Pulse) may be used.

In the present invention, the entire section of the normalized pulse wave pattern obtained by the pulse wave signal normalization unit 140 is divided into 29 window sections, and the minimum amplitude value in each window is detected. The minimum amplitude values detected in each window of the same subject are shown in Fig. 7 (a), and the minimum amplitude values using the pulse wave signal normalized by the pulse wave signal normalization unit 140 are shown in Fig. 7 (b) .

The vascularization analyzer 160 analyzes the degree of vascularization using the minimum amplitude values of the first window interval and the second window interval detected by the pulse wave amplitude detector 150 at step S214. In addition, the vascularization analyzer 160 can analyze the degree of vascularization by averaging the minimum amplitude values in the first window interval and the second window interval detected by the pulse wave amplitude detector 150, have.

In the pulse wave amplitude detector 150, the minimum amplitude value is detected for each window section. However, if there is no personal characteristic analyzer to be described later, the first and second window sections of the plurality of window sections The minimum amplitude value can be detected.

8 shows the arteriosclerosis analyzed by using the difference between the minimum amplitude values of the first window section and the second window section of the normalized pulse wave signal in the vascularization analyzer 160. In FIG. 8, when the subject is hypertension or pseudohypertension, atherosclerosis is indicated as a positive number. However, in general classification, the arterial sclerosis may be expressed as a negative value when the subject is physically hypertensive.

8, the difference between the minimum amplitude value of the second window interval detected by the pulse wave amplitude detector 150 and the minimum amplitude value of the first window interval is positive, The greater the value of arterial stiffness, the higher the value of arterial stiffness is analyzed.

9 to 11 are charts showing the average distribution of atherosclerosis according to the classification of hypertension, pseudohypertension and normotension from 85 persons of Canadian persons aged 20 to 80 years.

12 to 14 show hypertension, physiologic hypertension and normotensive blood pressure data of 180 Korean Koreans aged 20 to 80 years at the time of comprehensive medical examination and show an average distribution of atherosclerosis according to the classification FIG.

9 to 14, it can be seen that the difference between the minimum amplitude value of the first window interval and the minimum amplitude value of the second window interval is similar to the classification of hypertension, pseudohypertension, and normal blood pressure in both Koreans and Canadians . The reason why the characteristics of the minimum amplitude values of the first window section and the second window section used in the present invention can be common to both Koreans and Canadians is that the velocity of the pulse waves reflected at the systolic phase is higher than that of the pulse wave velocity , Whereas it is a tendency to show a slow pulse wave velocity at a normal blood pressure with a low degree of arteriosclerosis.

FIG. 15 is a view illustrating an apparatus for measuring blood vessel hardening based on measurement of an oscillometric metastatic arterial blood pressure according to another embodiment of the present invention.

15, the blood coagulation measuring apparatus 1500 includes a cuff 110, a pressure detecting sensor unit 120, a pulse wave extracting unit 130, a pulse wave signal normalizing unit 140, A personal characterization unit 1510 in addition to the amplitude detection unit 150, the vascularization analysis unit 160, the storage unit 170, and the display unit 180.

The cuff 110 is wrapped around a measurement site when measuring blood pressure and is wound around an arm or a cuff and connected to a pressurizing pump (not shown) and an exhaust valve (not shown) through an internal pipe (not shown) do.

The pressure detecting sensor unit 120 is connected to the cuff 110 through an internal pipe to detect a cuff pressure including an influence of a pulse wave, that is, a pressure of the cuff 110.

The pulse-wave extraction unit 130 extracts a pulse wave signal of an artery of the entire section from the cuff pressure detected by the pressure detection sensor unit 120. On the other hand, when a plurality of pulse wave signals are to be obtained from the same subject for normalizing the pulse wave signal, the pulse wave signal extracted by the pulse wave extraction unit 130 is stored in the pulse wave signal storage region of the storage unit 170.

The pulse-wave-signal normalization unit 140 normalizes a plurality of pulse-wave signals extracted from the pulse-wave extraction unit 130 obtained from the same subject, in order to reduce a change in the pulse- ) To output a normalized pulse wave signal of the subject.

The pulse wave amplitude detector 150 divides the pulse wave signal inputted to the pulse wave extractor 130 or the normalized pulse wave signal of the subject into a plurality of window sections and outputs a minimum amplitude value MIAP (Minimum Amplitude Pulse) .

The vascularization analyzer 160 analyzes the degree of vascularization using the minimum amplitude values of the first window interval and the second window interval detected by the pulse wave amplitude detector 150.

The personal characteristics analyzing unit 1510 analyzes the blood vessel hardening degree analyzed by the blood vessel hardening analyzing unit 160 and the presence or absence of hypertension using the minimum amplitude value in each window region detected by the pulse wave amplitude detecting unit 150, , That is, the relationship between hypertension and the degree of vascular hardening.

The display unit 180 displays information on the blood vessel hardening degree analyzed by the blood vessel hardening analysis unit 160 and personal characteristic information analyzed by the individual characteristic analysis unit 1510 such as hypertension of the subject, And the effect of vasculopathy on hypertension and the like can be displayed.

16 is a flowchart showing a method for measuring vascular hardening based on the measurement of the oscillometric metastatic arterial blood pressure shown in Fig.

When the cuff 110 is wound around the arm or cuff of the human body, and the vascular cure measuring device 900 operates to measure the blood pressure, the cuff pressure is detected through the pressure detecting sensor unit 120 (S202).

The cuff pressure detected by the pressure detection sensor unit 120 is extracted from the pulse wave signal of the artery of the entire section by the pulse wave extraction unit 130 (S204).

The pulse wave signal extracted by the pulse wave extraction unit 120 may be stored in the storage unit 170 until a plurality of pulse wave signals are obtained from the same subject (S206).

When the number of times of measurement for the same subject reaches N times, the pulse-wave-signal normalization unit 140 performs normalization to reduce a change in the pulse-wave signals showing a change for each measurement count of the same subject (S208 ).

The pulse wave amplitude detector 150 divides the whole interval of the normalized pulse wave signal obtained by the pulse wave signal normalization unit 140 into a plurality of window intervals (S210).

The pulse-wave amplitude detector 150 detects a minimum amplitude value in each of the plurality of window sections (S1602).

The vascularization analyzer 160 analyzes the degree of vascularization using the minimum amplitude values of the first window interval and the second window interval detected by the pulse wave amplitude detector 150 at step S214. In addition, the vascularization analyzer 160 can analyze the degree of vascularization by averaging the minimum amplitude values in the first window interval and the second window interval detected by the pulse wave amplitude detector 150, have.

The personal characteristics analyzing unit 1510 analyzes the blood vessel hardening degree analyzed by the blood vessel hardening analyzing unit 160 and the presence or absence of hypertension using the minimum amplitude value in each window region detected by the pulse wave amplitude detecting unit 150, (S1604). Preferably, the personal characteristics analyzer 1510 averages the minimum amplitude values in each window section detected by the pulse wave amplitude detector 150 for each subject to analyze the personal characteristics. These averaged minimum amplitude values are shown in Figures 17 and 18 as individual characteristic patterns. FIG. 17 shows the individual characteristic patterns of the subjects P1 to P4 analyzed as systolic blood pressure to hypertension. FIG. 18 shows the individual characteristic patterns of the subjects P5 to P8 normally analyzed in the systolic blood pressure, .

17 and 18, in the case of subjects having high blood pressure, the largest value among the averaged minimum amplitude values detected by the pulse wave amplitude detector 150 in each window section is 1/3 of the measurement period .

17, the individual subjects P2 and P4 may be classified into the pre-hypertensive group or the subject P2. In this case, It can be seen that the normalized minimum amplitude value of the first window section is larger than the normalized minimum amplitude value of the second window section unlike the measurer P4.

In general, hypertension refers to a state of high blood circulation in the heart. In addition to atherosclerosis, the elasticity due to aging may be reduced, or the blood increase due to an increase in the salt intake may cause a heart burden leading to blood circulation, It is affected by eating habits and obesity.

FIG. 19 is a graph showing the minimum amplitude value in each window section of a subject who is a '47-year-old Korean male, belonging to a hypertensive group of 140/80 mmHg and' obese '.

As shown in FIG. 19, the subject belongs to the hypertensive group but the difference value obtained by subtracting the minimum amplitude value of the first window section from the minimum amplitude value of the second window section is negative.

20 is a 23-year-old Korean male showing a minimum amplitude value in each window section of a subject in the hypertensive group of 144/81 mmHg.

As shown in FIG. 20, the subject belongs to the hypertensive group, but the difference value obtained by subtracting the minimum amplitude value of the first window section from the minimum amplitude value of the second window section is negative. As seen from the age of the subject, the vascular contractility is more elastic than that of the elderly, suggesting that the arteriosclerosis belongs to the normal group.

Generally, hypertension is highly correlated with atherosclerosis, but hypertension and atherosclerosis do not always correspond, as can be seen from Figs. 19 and 20. Therefore, it is more effective to include the arteriosclerosis analysis according to the present invention in analyzing personal characteristics.

The foregoing description is merely illustrative of the technical idea of the present invention, and various changes and modifications may be made by those skilled in the art without departing from the essential characteristics of the present invention. Therefore, the embodiments disclosed in the present invention are intended to illustrate rather than limit the scope of the present invention, and the scope of the technical idea of the present invention is not limited by these embodiments. The scope of protection of the present invention should be construed according to the following claims, and all technical ideas falling within the scope of the same shall be construed as falling within the scope of the present invention.

110: cuff 120: pressure detection sensor part
130: a pulse-wave extracting unit 140: a pulse-wave-signal normalizing unit
150: pulse wave amplitude detector 160:
170: storage unit 180: display unit
1510: Personal characteristic analysis section

Claims (12)

A pressure detection sensor unit for detecting a cuff pressure including an influence of a pulse wave,
A pulse wave extracting unit for extracting an arterial pulse wave signal from the cuff pressure detected by the pressure detecting sensor unit;
A pulse wave amplitude detector for detecting a minimum amplitude value of the first window section and a minimum amplitude value of the second window section among the plurality of window sections,
And a blood vessel coagulation analyzing unit for analyzing the degree of vascularization using the minimum amplitude value of the first window interval and the minimum amplitude value of the second window interval detected by the pulse wave amplitude detector. An apparatus for measuring blood vessel hardening based on arterial blood pressure measurement. The method according to claim 1,
Wherein the vascularization analyzer analyzes the degree of vascularization using a difference between a minimum amplitude value of the first window interval and a minimum amplitude value of the second window interval detected by the pulse wave amplitude detection unit. An apparatus for measuring blood vessel hardening based on blood pressure measurement. 3. The method of claim 2,
And a pulse wave signal normalization unit for generating a normalized pulse wave signal using the plurality of pulse wave signals extracted from the same subject and outputting the normalized pulse wave signal to the pulse wave amplitude detection unit,
Wherein the pulse-wave amplitude detecting unit divides the normalized pulse-wave signal output from the pulse-wave-signal normalizing unit into the plurality of window periods, and calculates a minimum amplitude value of the first window period and a minimum amplitude value of the second window period Wherein the amplitude value is detected based on an oscillometric meta-arterial blood pressure measurement. The method of claim 3,
Wherein the pulse-wave-signal normalization unit normalizes the plurality of pulse-wave signals extracted from the pulse-wave-extracting unit by squaring each of the plurality of pulse-wave signals and routing the sum. 5. The method of claim 4,
The vascular cure analyzer analyzes that the difference value obtained by subtracting the minimum amplitude value of the first window section from the minimum amplitude value of the second window section detected by the pulse wave amplitude detecting section is positive and the arterial hardening degree is high as the value is positive And the arteriosclerosis degree is lower as the value is smaller and the value is smaller. The apparatus for measuring blood vessel hardening based on the measurement of an oscillometric metastatic arterial blood pressure. The method according to claim 3 or 4,
Wherein the pulse-wave amplitude detecting unit detects a minimum amplitude value in each window section of the plurality of windows,
And a personal characteristics analyzing unit for analyzing individual characteristics using hypertension using the minimum amplitude value in each window section detected by the pulse wave amplitude detecting unit and the vascular hardening degree analyzed in the vascularization analyzing unit An apparatus for measuring blood vessel hardening based on an oscillometric arterial blood pressure measurement. The method according to claim 6,
Wherein the number of windows dividing the pulse wave signal extracted from the pulse wave extraction section into the plurality of window sections is obtained based on the number of minimum vibration waveforms and the number of pulse vibration waveforms including one pulse of the maximum period. An apparatus for measuring blood vessel hardening based on blood pressure measurement. Detecting a cuff pressure including an influence of a pulse wave from a cuff wound on an arm or a cuff of the subject,
Extracting an arterial pulse wave signal from the detected cuff pressure;
Dividing the extracted pulse wave signal into a plurality of window sections, detecting a minimum amplitude value of the first window section and a minimum amplitude value of the second window section of the plurality of window sections,
And analyzing the degree of vascularization using the minimum amplitude value of the first window interval and the minimum amplitude value of the second window interval, based on the measurement of the arterial blood pressure. 9. The method of claim 8,
Wherein the step of analyzing the degree of vascularization comprises analyzing a degree of vascularization using a difference between a minimum amplitude value of the first window section and a minimum amplitude value of the second window section, Way. 10. The method according to claim 8 or 9,
Further comprising generating and outputting a normalized pulse wave signal using the extracted plurality of pulse wave signals obtained from the same subject,
Wherein the step of detecting the minimum amplitude value of the first window interval and the minimum amplitude value of the second window interval comprises calculating a minimum amplitude value of the first window interval and a minimum amplitude value of the second window interval using the normalized pulse wave signal, And detecting an amplitude value of the arterial blood pressure. 11. The method of claim 10,
Wherein the step of detecting the minimum amplitude value of the first window interval and the minimum amplitude value of the second window interval comprises detecting a minimum amplitude value in each window interval of the plurality of windows,
Further comprising the step of analyzing individual characteristics using the detected hypertension using the minimum amplitude value in each window section and the vascular hardening degree analyzed in the vascularization analyzing section, Methods for measuring vascularization. 12. The method of claim 11,
Wherein analyzing the personal characteristics comprises analyzing individual characteristics by averaging the minimum amplitude values in each window segment obtained for each subject for each window segment.

Images