KR20140064139A - Hydrogel sheet having capillary gel-net structure used cellulose and manufacturing method thereof - Google Patents

Abstract

The present invention relates to a hydrogel sheet having a capillary gel-net structure using cellulose comprising a step of forming a fiber material; a primary impregnation step; a net hole maintaining step; a step of preparing base release paper; a step of spraying high-concentration hydrogel; a step of immersing a fiber material; a step of fast-cooling; and a step of mounting upper release paper and a manufacturing method thereof. The present invention as described above uses a hydrogel fiber material having a capillary net structure and low-concentration hydrogel surrounding the same to evenly distribute to prevent difference of dryness and has an effect of being applied as a novel drug transferring system which is used as sustained release formulation which inhibits skin trouble.

Description

Technical Field [0001] The present invention relates to a hydrogel sheet having a capillary gel network structure using cellulose,

The present invention relates to a hydrogel sheet having a capillary gel structure using natural cellulose and a method for producing the hydrogel sheet. More particularly, the present invention relates to a hydrogel sheet having a capillary net structure capable of effectively promoting the effect of osmosis by concentration change, It is guided to be dispersed evenly throughout the fiber material and the low concentration hydrogel that surrounds it, so that the difference in drying is not generated. The low concentration of hydrogel is contained, so that the hydrogel is relatively soft and the skin closeness is high. It has a capillary gel structure with a cellulose capillary gel structure that can be applied as a new drug delivery system that is used as a slow release drug that low-concentration polymer gel is impregnated with water-soluble cosmetic ingredients or drugs at a high concentration, Rogel relates to a sheet and a method of manufacturing the same.

Generally, cellulose is a kind of simple polysaccharide mainly composed of higher plants, algae cell membranes and fibers, also called cellulose. Wood, cotton, hemp, etc., and the simplest cellulosic is cotton. It is hydrolyzed by acid, but is insoluble in water and resistant to chemicals. In addition to being a raw material for paper and clothing, methylethylated by chemical treatment is used as defoamer and dispersant.

Jelly, tofu, and gelatin are called gel states in chemistry. It is a substance that solidifies into a solid or a semi-solid by entering particles into a solution. Among these, hydrogel is called a solution.

The sheet-like pack using this hydrogel can relieve skin tension, skin moisturization, elasticity enhancement, wrinkle reduction, removal of dirt and contaminants from skin surface, removal of old keratin, removal of extra sebum , The smoothness of the skin, the psychological stabilizing effect, and the function of nutrition. The sheet-like mask is used in the form of a hydrogel coated on a support such as a nonwoven fabric or woven fabric. Examples of the hydrogel include crosslinking of a water-soluble polymer of polyacrylic acid type, polyether type, polyvinyl alcohol type, cellulose induction system, animal or plant extract system, or adhering of the substance itself. Examples of the production method of the sheet-like hydrogel include a method of mixing a fibroin aqueous solution and a substance selected from the group consisting of alginate, cellulose and agar, and gelling the mixture with a polyvalent metal.

However, the hydrogel sheet, which is a hydrogel structure made using conventional polyester net (Net), has a problem in that a portion having a narrow width of a cut surface portion or a hydrogel is dried faster than another wide portion, There is a structural problem that a difference is generated and a foreign body feeling is much felt during use.

The present invention has been made to solve the above problems, and it is an object of the present invention to provide a hydrogel fiber material, which is a capillary net structure capable of effectively promoting the effect of osmoticity due to a concentration change, and a low- The hydrogel is relatively soft and the skin closeness is enhanced because the low concentration of the hydrogel is contained and the water soluble cosmetic ingredient or drug is added to the low concentration polymer gel by the dual hydrogel structure. And a method for manufacturing the hydrogel sheet. The present invention provides a hydrogel sheet having a capillary gel network structure using cellulose as a novel drug delivery system that is used as a sustained release preparation for suppressing skin troubles by gradually releasing .

In order to achieve the above object, a method for producing a hydrogel sheet having a capillary gel network structure using cellulose according to the present invention comprises the steps of forming a cellulose fiber fiber material A reforming step;

A first impregnation step of firstly impregnating the cellulose fiber material with 0.01 to 0.49% low concentration hydrogel;

A mesh hole holding step of blowing and drying the cellulose fiber fiber material subjected to the primary impregnation step while maintaining the shape of the net hole which is a net cell; And

And a quenching step of quenching the cellulose fiber fiber material having the mesh holes through the mesh hole holding step by coating or coating with a 0.5 to 3.0% high concentration hydrogel.

The method for producing a hydrogel sheet having a capillary gel network structure using cellulose according to the present invention comprises: a fiber reformation step of forming a cellulosic fibrous fibrous material entangled in a net shape or a mesh shape with a cellulosic fiber;

A first impregnation step of firstly impregnating the cellulose fiber material with 0.01 to 0.49% low concentration hydrogel;

A mesh hole holding step of blowing and drying the cellulose fiber fiber material subjected to the primary impregnation step while maintaining the shape of the net hole which is a net cell;

Preparing a base release sheet for providing a base release sheet used as a base;

A high concentration hydrogel applying step of applying a 0.5 to 3.0% high concentration hydrogel to the top surface of the base release paper;

A fiber material impregnation step of impregnating a cellulose fiber fiber material having mesh holes through the mesh hole holding step by placing it on the upper surface of the 0.5 to 3.0% high concentration hydrogel;

A quenching step of quenching the cellulose fiber fiber material having the mesh holes impregnated on the upper surface of the 0.5 to 3.0% high concentration hydrogel; And

And an upper release paper placing step of placing the upper release paper on the upper surface of the cellulose fiber fiber material subjected to the quenching step.

The cellulose fiber material is characterized in that either woven fabric or nonwoven fabric is selectively used.

Further, in the hydrogel sheet having a capillary gel network structure using cellulose of the present invention,

Cellulosic fibers of woven or nonwoven fabric entangled in a net or net shape with cellulose fibers;

A 0.01 to 0.49% low concentration hydrogel which surrounds the outer surface of the cellulosic fiber material while being impregnated with the cellulose fiber material, And

And a 0.5 to 3.0% high concentration hydrogel surrounding the outer surface of the low concentration hydrogel of 0.01 to 0.49% of the cellulosic fiber material having the mesh hole.

The 0.5 to 3.0% high concentration hydrogel has a base release sheet at the lower end and an upper release sheet at the upper end.

As described above, the present invention differs from the prior art in that the difference in drying is caused by the hydrogel fiber material, which is a capillary net structure capable of effectively promoting the osmotic effect due to the concentration change, and the low concentration hydrogel surrounding the fiber material And the hydrogel is relatively soft and the skin closeness is enhanced. The dual hydrogel structure infiltrates a water-soluble cosmetic ingredient or a drug at a high concentration in the low concentration polymer gel, As a slow releasing agent which suppresses skin troubles, and thus can be applied as a new drug delivery system.

It will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined in the appended claims and their equivalents. Of course, such modifications are within the scope of the claims.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is an enlarged plan view of a hydrogel fiber material according to a method for producing a hydrogel sheet having a capillary gel network structure using cellulose as an embodiment of the present invention;
FIG. 2 is a view showing a hydrogel fiber material impregnated with a low-concentration hydrogel according to a method for producing a hydrogel sheet having a capillary gel network structure using cellulose, which is an embodiment of the present invention, and then a net hole is formed by air- Enlargement of floor space floor plan,
FIG. 3 is a graph showing the results of a method of producing a hydrogel sheet having a capillary gel network structure using cellulose, which is an embodiment of the present invention, in which a hydrogel fiber material impregnated in a low density hydrogel is impregnated again with a high- Expanded front section,
FIG. 4 is a cross-sectional view illustrating a hydrogel sheet prepared according to a method for producing a hydrogel sheet having a capillary gel network structure using cellulose as an embodiment of the present invention.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, the present invention will be described in more detail with reference to the accompanying drawings.

In the following description of the present invention, a detailed description of known functions and configurations incorporated herein will be omitted when it may make the subject matter of the present invention rather unclear.

In addition, the terms described below are defined in consideration of the functions of the present invention, which may vary depending on the user, the intention or custom of the operator, and the like.

Therefore, it goes without saying that the definition should be based on the contents throughout this specification.

The method for producing a hydrogel sheet having a capillary gel network structure using cellulose according to the present invention comprises the steps of forming a fiber material forming a cellulosic fiber material (10) which is entangled in a net shape or a net shape with a cellulosic fiber as a woven fabric or a non- A first impregnation step of first impregnating the cellulose fiber material 10 with 0.01 to 0.49% low concentration hydrogel 20, and a second impregnation step of immersing the cellulose fiber material 10 having been subjected to the first impregnation step in air A base release sheet preparation step of preparing a base release sheet 30 to be used as a base and a base release sheet preparation step of forming a base release sheet 30 on the top surface of the base release sheet 30, A high-concentration hydrogel applying step of applying a high-concentration hydrogel 40 of about 3.0% by weight to the high-concentration hydrogel 40, A fibrous material impregnation step of placing the fibrous fibrous material 10 on the upper surface of the 0.5 to 3.0% high concentration hydrogel 40 and impregnating the fibrous material 10 with the molten metal 21 impregnated on the upper surface of the 0.5 to 3.0% A step of cooling the cellulosic fibrous material 10 with a rapid cooling step and a step of securing the upper release material 50 on the upper surface of the cellulose fiber material 10 after the rapid cooling step.

The hydrogel sheet 1 having a capillary gel network structure using the cellulose of the present invention comprises a cellulose fiber material 10 of a woven or nonwoven fabric entangled in a net shape or a net shape with a cellulose fiber, The cellulosic fiber material 10 is impregnated and cooled to cool the cellulosic material 21 while being held at the cellulosic material 21. The cellulosic fiber material 20 has a density of 0.01 to 0.49% And a 0.5 to 3.0% high concentration hydrogel (40) surrounding the outer surface of the low concentration hydrogel (20) of 0.01 to 0.49% of the high concentration hydrogel (10). The upper release film 50 is positioned at the upper end of the 0.5 to 3.0% high concentration hydrogel 40 and the base release film 30 is positioned at the lower end.

The cellulose is a natural cellulose obtained from cotton and the like, and is a polymer fiber composed of polysaccharide, and has a structure in which a large number of hydroxides are exposed on the surface, and is the most excellent in hygroscopicity and hydration affinity.

The present invention relates to a low-concentration hydrogel (20) having a concentration of 0.01 to 0.49% by using a cellulose fiber material (10) which is a nonwoven fabric or a woven fabric knitted in a net shape or a net shape by using a natural cellulose fiber The mesh hole 21 as a net cell is maintained and dried by air blowing and then the high concentration hydrogel 40 having a concentration of 0.5 to 3.0% is applied or coated on the mesh hole 21 to be quenched and cooled to obtain a cellulosic fiber material 10 The hydrogel sheet 1 in which the gel structure of low concentration is in the range of 0.01 to 0.49% and the gel structure of the high concentration hydrogel 40 in the range of 0.5 to 3.0% coated therewith is formed.

The hydrogel sheet 1 of the present invention has a high concentration of the hydrogel 40 net unit cell having a low concentration hydrogel 20 having a texture of 0.01 to 0.49% containing the cellulose fiber material 10 of 0.5 to 3.0% (20) net (0.01 to 0.49%), which is surrounded by a mesh hole (21) which is a net unit cell, and which is coated with a high concentration of hydrogel (40) (Net) is formed.

Within this overall structure, the hydrogel 20 at a low concentration of 0.01 to 0.49% and the physically structured cellulosic fibrous fiber material 10 have a high concentration of the hydrogel 40 of 0.5 to 3.0% due to the capillary effect, And serves as a moving passage for water or other water-soluble ingredients therein.

The present invention was invented as a hydrogel sheet (1), which is a structure capable of maximizing the capillary effect. As a result, conventionally, the difference in external environment, that is, the difference in temperature and structural difference between the skin- There has been a problem that a portion of the hydrogel having a narrow width is relatively rapidly thinned due to a large number of cutting sites. However, in the present invention, a capillary net capable of effectively performing osmotic effects due to concentration changes In response to the change through the structure, water or a water soluble drug is structurally guided to be dispersed evenly through the capillary net hydrogel fiber material 10 and the low concentration hydrogel 20 surrounding it do.

Also, since the hydrogel 20 having a lower concentration than that of the conventional single structure hydrogel is contained therein, the hydrogel is relatively soft and the skin intimacy is enhanced.

In addition, it can be applied as a new drug delivery system (double drug delivery system) in which a low concentration polymer gel is impregnated with a water-soluble cosmetic ingredient or a drug at a high concentration and slowly released into a skin attachment surface, .

1: Hydrogel sheet
10: hydrogel fiber material
20: Low concentration hydrogel
21: mesh hole (net cell)
30: Base release
40: High concentration hydrogel
50: upper release paper

Claims (4)

A fiber reformation step of forming a cellulose fiber material of a woven or nonwoven fabric entangled in a net shape or a net shape with a cellulose fiber;
A first impregnation step of firstly impregnating the cellulose fiber material with 0.01 to 0.49% low concentration hydrogel;
A mesh hole holding step of blowing and drying the cellulose fiber fiber material subjected to the primary impregnation step while maintaining the shape of the net hole which is a net cell; And
And a quenching step of rapidly cooling the cellulose fiber material having mesh holes through the mesh hole holding step by applying or coating the cellulose fiber material with 0.5 to 3.0% high concentration hydrogel. A fiber reformation step of forming a cellulosic fibrous fibrous material entangled in a net shape or a net shape with a cellulose fiber;
A first impregnation step of firstly impregnating the cellulose fiber material with 0.01 to 0.49% low concentration hydrogel;
A mesh hole holding step of blowing and drying the cellulose fiber fiber material subjected to the primary impregnation step while maintaining the shape of the net hole which is a net cell;
Preparing a base release sheet for providing a base release sheet used as a base;
A high concentration hydrogel applying step of applying a 0.5 to 3.0% high concentration hydrogel to the top surface of the base release paper;
A fiber material impregnation step of impregnating a cellulose fiber fiber material having mesh holes through the mesh hole holding step by placing it on the upper surface of the 0.5 to 3.0% high concentration hydrogel;
A quenching step of quenching the cellulose fiber fiber material having the mesh holes impregnated on the upper surface of the 0.5 to 3.0% high concentration hydrogel; And
And a top releasing sheet placing step of placing the top releasing paper on the top surface of the cellulose fiber fiber material subjected to the quenching step. Cellulosic fibers of woven or nonwoven fabric entangled in a net or net shape with cellulose fibers;
A 0.01 to 0.49% low concentration hydrogel which surrounds the outer surface of the cellulosic fiber material while being impregnated with the cellulose fiber material, And
A hydrogel sheet having a capillary gel net structure using cellulose having 0.5 to 3.0% high concentration hydrogel surrounding the outer surface of a 0.01 to 0.49% low concentration hydrogel of the cellulose fiber material having the mesh hole. 4. The method of claim 3, further comprising:
A hydrogel sheet having a capillary gel network structure using cellulose, characterized in that a base release sheet is provided at the lower end of the 0.5 to 3.0% high concentration hydrogel, and an upper release sheet is provided at the upper end.

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