KR20120105429A - 염증 치료 방법 - Google Patents

염증 치료 방법 Download PDF

Info

Publication number
KR20120105429A
KR20120105429A KR1020127010455A KR20127010455A KR20120105429A KR 20120105429 A KR20120105429 A KR 20120105429A KR 1020127010455 A KR1020127010455 A KR 1020127010455A KR 20127010455 A KR20127010455 A KR 20127010455A KR 20120105429 A KR20120105429 A KR 20120105429A
Authority
KR
South Korea
Prior art keywords
mif
peptide
disease
seq
motif
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020127010455A
Other languages
English (en)
Korean (ko)
Inventor
위르겐 베른하겐
크리스티안 베버
베네딕트 폴라트
코트 터너
조슈야 로버트 슐츠
알마 체르네케
세르히오 듀론
Original Assignee
카롤러스 테라퓨틱스, 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 카롤러스 테라퓨틱스, 인코포레이티드 filed Critical 카롤러스 테라퓨틱스, 인코포레이티드
Publication of KR20120105429A publication Critical patent/KR20120105429A/ko
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020127010455A 2009-09-23 2010-09-23 염증 치료 방법 Withdrawn KR20120105429A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24521409P 2009-09-23 2009-09-23
US61/245,214 2009-09-23
US31903910P 2010-03-30 2010-03-30
US61/319,039 2010-03-30

Publications (1)

Publication Number Publication Date
KR20120105429A true KR20120105429A (ko) 2012-09-25

Family

ID=43796491

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020127010455A Withdrawn KR20120105429A (ko) 2009-09-23 2010-09-23 염증 치료 방법

Country Status (9)

Country Link
EP (1) EP2480579A4 (enExample)
KR (1) KR20120105429A (enExample)
CN (1) CN102725311A (enExample)
AU (1) AU2010298249A1 (enExample)
BR (1) BR112012006468A2 (enExample)
CA (1) CA2773978A1 (enExample)
IN (1) IN2012DN02423A (enExample)
MX (1) MX2012003514A (enExample)
WO (1) WO2011038149A2 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013010955A1 (en) 2011-07-15 2013-01-24 Morphosys Ag Antibodies that are cross-reactive for macrophage migration inhibitory factor (mif) and d-dopachrome tautomerase (d-dt)
US9328174B2 (en) * 2012-05-09 2016-05-03 Novartis Ag Chemokine receptor binding polypeptides
CA2873808C (en) * 2012-05-17 2021-04-27 Cyon Therapeutics Inc. Methods and uses for proprotein convertase subtilisin kexin 9 (pcsk9) inhibitors
TW201605886A (zh) * 2013-11-14 2016-02-16 巴克斯特保健公司 作爲治療標靶的mif
MX386771B (es) 2016-03-11 2025-03-19 Ardea Biosciences Inc Inhibidores de cxcr-2 para tratamiento de trastornos de artropatía por cristales.
AU2019282132A1 (en) 2018-06-05 2020-12-17 Anji Pharmaceuticals Inc. Compositions and methods for treating pancreatitis
CA3123290A1 (en) * 2018-12-26 2020-07-02 Colgate-Palmolive Company Biomarkers of neutrophil deregulation as diagnostic for gingivitis
EP4117704A4 (en) * 2020-03-11 2024-04-10 BioLineRx Ltd. Cxcr4 inhibitor for the treatment of acute respiratory distress syndrome and viral infections
WO2021219495A1 (en) * 2020-04-28 2021-11-04 Dalcor Pharma Uk Ltd., Leatherhead, Zug Branch Methods for treating or preventing a viral infection or inhibiting viral replication
CN112656934A (zh) * 2021-01-22 2021-04-16 深圳市图微安创科技开发有限公司 多肽at03在治疗原发性胆汁性胆管炎药物中的应用
EP4378319A1 (en) * 2022-12-01 2024-06-05 Bioiberica, S.A.U. Composition comprising bioactive peptides
CN119318647A (zh) * 2024-08-14 2025-01-17 南方医科大学 Sb225002在制备治疗心肌梗死的药物中的应用、治疗心肌梗死的组合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7534605B2 (en) * 1999-06-08 2009-05-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases
WO2003072753A2 (en) * 2002-02-27 2003-09-04 Emory University Multimeric binding complexes
WO2003074567A2 (en) * 2002-03-01 2003-09-12 Immunomedics, Inc. Internalizing anti-cd74 antibodies and methods of use
WO2005065328A2 (en) * 2003-12-30 2005-07-21 The United States Of America, As Represented By The Department Of Veterans Affairs Macrophage migration inhibitory factor (mif) as marker for urological inflammatory disease
US7612181B2 (en) * 2005-08-19 2009-11-03 Abbott Laboratories Dual variable domain immunoglobulin and uses thereof
EA201001529A1 (ru) * 2008-03-20 2011-06-30 Каролус Терапьютикс, Инк. Способ и композиция для лечения mif-опосредованных расстройств
WO2010056910A2 (en) * 2008-11-12 2010-05-20 Carolus Therapeutics, Inc. Methods of treating cardiovascular disorders

Also Published As

Publication number Publication date
MX2012003514A (es) 2012-04-19
IN2012DN02423A (enExample) 2015-08-21
WO2011038149A2 (en) 2011-03-31
WO2011038149A3 (en) 2011-10-27
AU2010298249A1 (en) 2012-04-19
BR112012006468A2 (pt) 2016-08-09
CA2773978A1 (en) 2011-03-31
EP2480579A2 (en) 2012-08-01
EP2480579A4 (en) 2013-07-31
CN102725311A (zh) 2012-10-10

Similar Documents

Publication Publication Date Title
US20110262386A1 (en) Methods of treating inflammation
KR20120105429A (ko) 염증 치료 방법
US20100093636A1 (en) Methods of treating inflammation
US20110256130A1 (en) Methods of treating inflammatory disorders
CN103459595B (zh) 针对人前列腺素e2受体ep4的抗体
AU2017347822B2 (en) Use of beta-catenin as a biomarker for treating cancers using anti-Dkk-1 antibody
BR112020020118A2 (pt) composto anti-cmklr1, molécula de ácido nucleico, vetor, célula hospedeira, produto de combinação, combinação de composto, método para selecionar um composto anti-cmklr1, e, composto agonista de cmklr1.
WO2011116245A2 (en) Methods of treating inflammation
US20240294633A1 (en) Antibody specific for anti-bcl-6 antibody and methods of use
JP7458049B2 (ja) 自己免疫疾患治療剤
US11912772B2 (en) Anti-galectin-9 antibody and methods of use thereof
BR112022006760B1 (pt) Anticorpo anti-receptor semelhante a quemerina 1 ou fragmentos de ligação ao antígeno do mesmo e usos preventivos ou terapêuticos do mesmo
HK40123789A (zh) 优化的抗tl1a抗体
HK40042163B (zh) 优化的抗tl1a抗体

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20120423

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid