KR20120084284A - Hydrogel patch - Google Patents

Abstract

PURPOSE: A hydrogel patch with a display unit is provided to enable a consumer to confirm a heat absorption state or the replacement time of the patch. CONSTITUTION: A hydrogel patch with a display unit comprises a hydrogel layer(10), a patch(20), and a display unit(30). The hydrogel layer includes gel which is manufactured using a dispersion medium including water. The patch is formed on the hydrogel layer. The display unit is printed on the patch. The display unit comprises a color change unit including thermochromic pigment.

Description

Hydrogel patch {Hydrogel patch}

The present invention relates to a hydrogel patch, and more particularly, to a hydrogel patch having a display unit indicating a state of use of the hydrogel patch.

Generally, skin adhesives are used for acne, wrinkles, roughness, stains, freckles, other treatments and alleviation, skin aging, such as skin aging paper. As such a skin adhesion agent, the adhesion patch apply | coated a fixed amount to nonwoven fabric, foamed plastics, etc. is used.

Recently, skin care using hydrogels has been widely applied as an attachment patch. Hydrogels are well known for their use as substrates for controlled release of drugs (NA Pappas ed., "Hydrogels in Medicine and Pharmacy, Vol. 11; Polymers", CRC Press, Inc.) , 1987). This is used as a drug carrier that uses a hydrogel as a matrix to contain hormones such as progesterone, thereby releasing hormones slowly and controlling the amount of hormone delivered to the body. US Patent No. 5,344,655 to Sakai et al. Discloses a technique for delivering drugs through the skin using a hydrogel base containing a water-soluble polymer such as a cellulose derivative. US Pat. No. 5,405,366 to Fox et al. Discloses a technique for making an adhesive hydrogel containing water-crosslinkable water-soluble polymers for use in transdermal drug delivery systems. U.S. Patent No. 4,593,053 to Zevner et al discloses the use of skin-friendly, pressure-sensitive hydrogels. In addition, US Pat. Nos. 6,361,790 and 6,406,712 to Rolf et al. Disclose a skin application method such as a dressing and a patch using a hydrogel.

Conventional technologies use a hydrogel in the form of a patch to deliver drugs or heat absorbing functions, but the situation is not known to the consumer about the degree of drug delivery, heat absorption or patch replacement time of these patches.

One object of the present invention for solving the above-mentioned problems of the prior art is to provide a consumer with a heat absorption state or an exchange time of a hydrogel patch.

One aspect of the present invention for achieving the above object is

A hydrogel patch comprising a hydrogel layer, an adhesive fabric formed thereon, and a display portion printed on the adhesive fabric, wherein the display portion is formed of a Zion pigment, and the hydrogel layer is in contact with the skin when the patch is attached to the skin. It relates to a hydrogel patch in which the color of the display portion is changed by the temperature rise.

Hydrogel patch according to the present invention by maintaining the temperature difference between the skin and the hydrogel 2 ~ 5 ℃ is excellent in the feeling and cooling effect on the skin. In addition, by providing the temperature difference visually through the display unit attached to the patch, the consumer can confirm the heat absorption state or replacement time of the patch.

1 is a schematic diagram of a hydrogel patch according to one embodiment of the present invention.
2 is a schematic diagram of a hydrogel patch according to another embodiment of the present invention.
Figure 3 is a schematic diagram showing the discoloration process of the hydrogel patch according to another embodiment of the present invention.
Figure 4 is a photograph of the color change in time / temperature changes after the hydrogel patch is attached to the skin.

Hydrogel patch according to an embodiment of the present invention includes a display unit showing the temperature difference between the skin and the hydrogel.

 Hereinafter, the present invention will be described in detail with reference to the accompanying drawings.

1 to 2 is a schematic diagram of a hydrogel patch according to one embodiment of the present invention.

Referring to FIG. 1, the hydrogel patch of the present invention includes a hydrogel layer 10, an adhesive cloth 20, and a display portion 30 printed on the adhesive cloth.

Referring to FIG. 1, the hydrogel layer 10 includes a gel prepared by using water or a component containing water as a dispersion medium. Hydrogel refers to a substance in which a solid molecule absorbs water (the absorption rate varies from material to material, but may absorb more than a few hundred percent of water) and does not dissolve but takes a structural form similar to a solid structure. (Mainly colloidal clay, etc.) materials. Hydrogel layer 10 of the present invention can be formed using a known hydrogel. For example, the hydrogel layer 10 may be formed using an acrylic polymer or natural polymer.

The adhesive cloth 20 is formed on the hydrogel layer 10, and a display unit is printed thereon. The hydrogel layer is formed on the attachment cloth 20 and functions to fix it. The adhesive cloth 20 may be formed of plastic films such as polyvinyl chloride, polyethylene, nylon, or biodegradable films such as acetyl cellulose. In addition, the adhesive fabric may be formed using any one of nonwoven fabric of pulp, linen-based natural fiber nonwoven fabric, synthetic short fiber nonwoven fabric made of polyethylene, polypropylene, nylon, polyethylene terephthalate or acrylic.

The display unit 30 includes a color change part 31 formed with Zion pigment.

Referring to FIG. 1, the display unit 30 may include a non-chromic unit 32 in which the color of the ink does not change in order to enhance the visual effect. The non-chromic part may use an ink material that is commonly used. On the other hand, the display unit 30 can provide a temperature change or a replacement time of the patch using only the discoloration unit 31.

As the color of the discoloration unit 31 disappears in the range of 24 to 36 ° C. or changes to one or more other colors, the color change part 31 may visually provide a consumer with a change in temperature or a patch.

On the other hand, the discoloration unit 31 is the first discoloration period to discolor when the patch is attached to the skin, the second discoloration period indicating that the water supply from the hydrogel layer is in progress, and the water supply is further progressed It may include a third discoloration section showing that not.

The first to third discoloration sections are displayed as the color change of the discoloration unit according to the temperature change of the patch, the first discoloration section has a temperature change range of 24 ~ 25 ℃, the second discoloration section 25 seconds and less than 32 ℃ The third discoloration section may be 32 ° C. or more.

The discoloration part may be displayed by printing a Zion composition on an adhesive cloth.

The Zion composition includes a binder, white and colored pigments, one or more Zion pigments, a solvent. The Zion composition may include 10 to 50% by weight of the binder, 1 to 20% by weight of pigment, 0.1 to 10% by weight of one or more Zion pigments, and a solvent to disperse them in the remaining amount.

The binder functions to fix the Zion pigment on the attachment cloth 20. Examples of the binder include acrylonitrile, styrene-acrylonitrile, methyl methacrylate-butadiene-styrene, butadiene, acryl, urethane, epoxy, phenoxy, polyamide, olefin, and silicone resins. It can be used individually or in mixture of 2 or more types, Preferably urethane resin, acrylic polymerizable resin, etc. can be used, but it is not necessarily limited to this.

The Zion composition may contain 10 to 50% by weight of the binder, preferably 15 to 35% by weight.

The pigment may be an organic pigment and / or inorganic pigments such as white, yellow, red as a color aid of the Zion pigment. Organic pigments include, for example, various lake pigments or mixtures thereof licensed for use in cosmetics, food, and the like.

As the inorganic pigment, zinc oxide, titanium dioxide, bengal, red pigment, ocher, yellow pigment, silica, and calcium carbonate may be used. Preferably, white to yellow color is used for the color pigment with Zion pigment. Preference is given to using pigments.

The pigment may be used 1 to 20% by weight, preferably 4 to 15% by weight. If it is used in less than 1% by weight may have a problem in that it does not give enough color to the discoloration part to exhibit a visual effect to the consumer, if it exceeds 20% by weight rather than without special improvement in color There may be a problem that reduces the essential content of the components to inhibit the physical properties of the composition and the like.

The Zion pigment refers to a pigment that changes color according to temperature, and the color begins to disappear as the temperature increases and then returns to the original color when the temperature decreases or vice versa.

In general, red Zion Pigment (RT-31), which changes color at 31 ° C, disappears at 33 ° C and returns to its original color when it is lowered to the original temperature. In the case of BT-20), the color appears as blue color below 20 ℃ and then disappears at 22 ℃. In addition, in the case of the orange Zion pigment (OT-31) which changes at 31 degreeC, when a heat is applied, a color disappears completely at 35 degreeC. Red Zion Pigment (RT-43), which changes at 43 ℃, loses its color at about 47 ℃ when heated to 43 ℃.

The Zion pigment may be used one or more of those currently known, but Zion Pigment discoloring at 24 ℃ ~ 32 ℃ is preferred.

Zion pigment composition of the present invention may exhibit a color change range of one or more, preferably 2 to 4 color at 24 ℃ ~ 32 ℃.

The Zion pigment may comprise 0.1 to 10% by weight, preferably 0.5 to 5% by weight. If less than 0.1% by weight it is difficult to express the desired color, if more than 10% by weight may have a problem such as economic efficiency.

Referring to FIG. 1, letters or patterns printed on the discoloration unit 31 may be discolored in a range of 24 ° C. to 32 ° C. FIG. More specifically, when the patch contacts the skin, the color of the discoloration part disappears due to the temperature increase of the hydrogel layer in contact with the skin, and thus, the letters cannot be recognized. As a result, the non-discoloration part 32 as shown in FIG. Only the letters of remain.

Referring to FIG. 2, when the color change part 31 is less than 24 ° C., the blue color is changed to light purple in the first color change section of 24 to 25 ° C., and the light color is less than 25 seconds and less than 32 ° C. as the second color change section. The color is changed to pink, and as the temperature rises, the color becomes pink gradually, and may change from gray to white in the third color change interval of 32 ° C or higher.

Figure 3 is a schematic diagram showing the discoloration process of the hydrogel patch according to another embodiment of the present invention.

Referring to FIG. 3, the discoloration part 31 includes a first discoloration part 311 that discolors at 24 to 25 ° C., and a second discoloration part 312 that discolors at 25 to 32 ° C. The first discoloration part 312 is printed with the first discoloration part and the second discoloration composition with the first Zion composition. The first Zion composition may be prepared by various methods. For example, the first Zion composition may be prepared by adjusting the content of 25T yellow and white pigment which are Zion pigments in the Zion composition.

Referring to a of FIG. 3, a letter "not attached" is printed on the first color change part 311, and a letter "in use" is printed on the second color change part 312. Referring to b of FIG. 3, when the patch is applied to the skin, the letters of the first discoloration part are discolored and not visible in the range of 24 to 25 ° C., so that only the letters “in use” and “replacement” remain in the patch. Referring to c of FIG. 3, after a predetermined time, the temperature of the patch rises a little more, and when the temperature reaches 32 ° C., the letters of the second discoloration unit “in use” are also discolored and disappeared, leaving only the letters “replacement”. It can tell you when to replace a patch.

On the other hand, in Figure 3, the letter "replacement" is shown as a non-colored part, but the first time the letters are not recognized using Zion pigment, the color appears when the temperature is above 32 ℃ so that the word "replacement" is visible Can be formed.

When the hydrogel patch of the present invention is attached to the skin, the temperature difference between the hydrogel layer and the skin is maintained for 20-30 minutes in the range of 2 ~ 5 ℃, the discoloration unit is represented by the discoloration of the Zion pigment change according to the temperature difference Can be. In the present invention, since the surface temperature (surface temperature of the nonwoven fabric) of the hydrogel layer and the patch is substantially similar, hereinafter, the temperature of the hydrogel layer and the temperature of the patch are the same.

The hydrogel layer 10 contains a lot of water and can generally exhibit a temperature of 22 to 26 ° C. On the other hand, the skin, especially the face, shows 32-34 ° C. When the hydrogel layer 10 of the patch is attached to the face, the surface temperature of the patch is about 29 to 30 ° C. after about 20 to 30 seconds, while the patch is in the vicinity of the patch (within 2 cm). The measured skin temperature can be reduced to 31 – 32 ° C.

The temperature difference between the hydrogel layer and the skin is preferably maintained at 2 ~ 5 ℃, preferably 3 ~ 4 ℃ range. When the temperature difference is maintained, the skin cooling effect is excellent, which may help beauty or treatment. It is preferable to maintain the temperature difference between the hydrogel layer and the skin for 20 minutes to 30 minutes or more.

In the present invention, the temperature difference between the hydrogel layer and the skin can be visualized and displayed on the patch.

Example  One

As a binder, 8 g of titanium dioxide (TiO ₂ , DuPont), a white pigment, was added to a stirrer containing 25 g of a urethane-based resin (MK-5040, 30% solids, Ming-Kwang Chemical) and 55 g of toluene, and then mixed and dispersed at 2500 rpm for 10 minutes. Subsequently, 0.7 g of 28T Blue (nano-I Entec), 0.3 g of 31T Red (nano-I Entec) and 11 g of toluene were further added to the stirrer to disperse the pigment to prepare a Zion composition.

The Zion composition was printed on a nonwoven fabric by a gravure coating method to prepare a hydrogel patch.

Figure 4 is a photograph of the color change in time / temperature changes after the hydrogel patch is attached to the skin. Referring to FIG. 4, the color of the discoloration part, which was a deep blue color, changed to light purple immediately after skin attachment (24.8 ° C.), and after 20 seconds (29.2 ° C.) having a large temperature rise, the color changed to pink, and then (32 ° C.) Pink disappears gradually

can confirm.

Although preferred embodiments of the present invention have been described in detail, these are for illustrative purposes only and the scope of protection of the present invention is not limited thereto.

10 hydrogel layer 20 adhesive cloth 30 display unit

Claims (7)

A hydrogel patch comprising a hydrogel layer, an attachment fabric formed thereon, and a display portion printed on the adhesion fabric, wherein the display portion includes a discoloration portion formed with a Zion pigment, and wherein the patch contacts the skin when the patch is attached to the skin. Hydrogel patch, characterized in that the color change of the color change part by the temperature rise of the hydrogel layer. The hydrogel patch of claim 1, wherein the color of the discoloration part disappears in a range of 24 ° C. to 36 ° C. or changes to one or more other colors. The method of claim 1, wherein the discoloration part includes a first discoloration section that discolors when the patch is attached to the skin, a second discoloration section indicating that the water supply from the hydrogel layer is progressing to the skin, and the water supply further progresses. Hydrogel patch, characterized in that it comprises a third discoloration section showing that not. The method of claim 3, wherein the first to third color change intervals are indicated by color change of the color change portion according to the temperature change of the patch, wherein the first color change interval is a temperature change range of 24 ~ 25 ℃, the second color change interval Silver 25 and less than 32 ℃ hydrogel patch, characterized in that the third discoloration section is more than 32 ℃. The method of claim 2, wherein the color change portion
A hydrogel patch characterized in that a Zion composition containing a solvent is printed on an adhesive cloth in 10 to 50% by weight of a binder, 1 to 20% by weight of a pigment, 0.1 to 10% by weight of one or more Zion pigments, and the remaining amount. 6. The hydrogel patch of claim 5, wherein the binder is at least one resin selected from the group consisting of acrylonitrile, butadiene, acryl, and urethane based weight average molecular weights in the range of 1,000 to 1,000,000. The method of claim 1, wherein when the patch is attached to the skin, the temperature difference between the hydrogel layer and the skin is maintained for 20 to 30 minutes in the range of 2 ~ 5 ℃, the discoloration unit changes the color difference of the Zion pigment Hydrogel patch, characterized in that.

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