KR20120068430A - Device for measuring blood ion and viscosity state - Google Patents

Device for measuring blood ion and viscosity state Download PDF

Info

Publication number
KR20120068430A
KR20120068430A KR1020100130050A KR20100130050A KR20120068430A KR 20120068430 A KR20120068430 A KR 20120068430A KR 1020100130050 A KR1020100130050 A KR 1020100130050A KR 20100130050 A KR20100130050 A KR 20100130050A KR 20120068430 A KR20120068430 A KR 20120068430A
Authority
KR
South Korea
Prior art keywords
blood
viscosity
measuring
ion
unit
Prior art date
Application number
KR1020100130050A
Other languages
Korean (ko)
Inventor
김기완
Original Assignee
주식회사 샤인
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 샤인 filed Critical 주식회사 샤인
Priority to KR1020100130050A priority Critical patent/KR20120068430A/en
Publication of KR20120068430A publication Critical patent/KR20120068430A/en

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/04—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/22—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4915—Blood using flow cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/028—Material parameters
    • G01N2291/02818—Density, viscosity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

PURPOSE: An apparatus for measuring ion and viscosity of blood from a body is provided to measure ion state and viscosity of the blood at high speed. CONSTITUTION: An apparatus for measuring ion and viscosity of blood form a body comprises an electric signal sensor(10), a high speed impedance measuring unit(30), and an output unit(70). The electric signal sensor comprises an auxiliary electrode(110) and working electrode(120) for generating and sensing pulse. The working electrode is formed of platinum, gold, and carbon rod. The electric signal sensor further comprises a standard electrode for measuring pulse. The output unit displays resistance value(Rs) and capacitance(Cd).

Description

Device for measuring blood ion and viscosity state extracted from living organisms

The present invention relates to a device for measuring the ion and viscosity state of blood extracted from a living body capable of measuring the ion and viscosity state of blood extracted from a living body, not in the living body at high speed by using electrical fast impedance and signal processing technology in real time. .

When blood flows through blood vessels, the physical properties of the blood (particularly the viscosity of the blood) play a large part among the factors that determine blood flow and blood pressure.

As the viscosity of the blood increases, the flow resistance increases, and the blood pressure increases, and the contact time between the blood and the endothelial cells along the outer wall of the branch tube increases, so that the probability of endothelial cell injury increases.

The general measurement of blood viscosity is a method of measuring the viscosity by flowing blood into a tube of a certain size for a certain time, or a method of measuring the rotational force by interfacial friction by contacting the blood to the rotating rotor. In addition, in order to measure the viscosity of blood, the catheter for intravascular impedance measurement was periodically inserted and the effect of the ex vivo measurement was minimized.

However, the insertion of the device in vivo is made only for a limited patient, not the general public, and the measurement outside the living body takes a long time to coagulate blood, making it difficult to measure accurately and at the same time expensive.

The present invention for solving the conventional problems of the blood extracted from the living body that can measure the ionic and viscosity state of the blood extracted from the living body, not in the living body using the electrical high-speed impedance and signal processing technology in real time It is an object to provide an ion and viscosity state measuring device.

The present invention for achieving the above object is an electrical signal detection unit consisting of an auxiliary electrode and a working electrode for generating and detecting a plurality of pulses in contact with the blood extracted from the living body as a single pulse;

A high-speed impedance measuring unit electrically connected to the electric signal detecting unit to calculate a resistance value Rs and a capacitance value Cd of blood from current data sensed by the working electrode;

And an output unit for outputting a resistance value and a capacitance value measured from the high-speed impedance measuring unit.

In particular, the resistance and capacitance values measured by the high-speed impedance measurement unit, and comparing with the resistance value and capacitance value of the normal person to determine whether or not normal comparison unit for outputting to the output unit; Do.

The ion and viscosity state measuring device of blood extracted from the living body of the present invention has the effect of measuring the ion and viscosity state of the blood extracted from the living body, not from the living body, at high speed by using electrical high speed impedance and signal processing technology in real time. have.

1 is a block diagram schematically showing the configuration of a device for measuring the ion and viscosity of blood extracted from a living body of the present invention.

Hereinafter, the ionic and viscosity state measuring device of the blood extracted from the living body of the present invention will be described in detail with reference to Examples.

1 is a block diagram schematically showing the configuration of a device for measuring the ion and viscosity of blood extracted from a living body of the present invention.

The device for measuring the ion and viscosity states of blood extracted from the living body of the present invention includes an electric signal detecting unit 10, a high speed impedance measuring unit 30, and an output unit 70 as shown in FIG. 1.

The electrical signal detection unit 10 is for generating and detecting a pulse made of a plurality of pulses in the blood extracted from the living body, and comprises an auxiliary electrode 110 and a working electrode 120.

The auxiliary electrode 110 is for applying a pulse made of a plurality of pulses in the blood extracted from the living body, made of platinum, etc., and made of a thin wire, a thin plate, or the like.

In addition, the working electrode 120 is for detecting a pulse applied to the blood from the auxiliary electrode, and is made of a material such as platinum, gold, or carbon rod.

On the other hand, the electrical signal detection unit 10 may be further provided with a reference electrode in order to more accurately measure the pulse passing through the blood.

The high speed impedance measuring unit 30 includes a signal generator and an impedance calculator. The signal generator is to output a plurality of pulses as a single pulse to the auxiliary electrode of the electrical signal detection unit. Conventionally, since a plurality of pulses are generated sequentially and then detected, it takes a long time, whereas the signal generator generates a plurality of pulses as a single pulse so that the ion and viscosity states of blood can be measured at high speed. have.

The impedance calculator calculates resistance and capacitance values using current data applied to the working electrode of the electrical signal detector.

Next, the output unit 70 displays the resistance value Rs and the capacitance value Cd calculated from the impedance calculator.

On the other hand, the resistance and capacitance value of the blood calculated by the impedance calculation unit is compared with the resistance and capacitance value of the blood of a normal person is preferably further provided with a comparison determination unit to determine whether or not normal. Specifically, since the resistance value of blood is determined by the amount of ions such as sodium and calcium in the blood, it is possible to determine whether the ion content in the blood is normal by comparing the resistance value of the blood of the normal person with the measured resistance value. have. In addition, as the capacitance of the blood decreases blood movement in the electrode double layer as the blood viscosity increases, as the capacitance decreases, it is possible to determine whether the blood viscosity is normal by comparing with the capacitance of a normal person.

The state of the ions and the viscosity of the blood determined by the comparison determination unit is displayed by the output unit 70.

10: electric signal detection unit,
30: high speed impedance measurement unit,
50: comparison judgment,
70: output unit

Claims (2)

An electrical signal detecting unit comprising an auxiliary electrode and a working electrode contacting the blood extracted from the living body to generate and detect several pulses as one pulse;
A high-speed impedance measuring unit electrically connected to the electric signal detecting unit to calculate a resistance value Rs and a capacitance value Cd of blood from current data sensed by the working electrode;
And an output unit for outputting a resistance value and a capacitance value measured from the high-speed impedance measuring unit.
The method of claim 1,
And comparing and comparing the resistance value and the capacitance value measured by the high-speed impedance measuring unit with the resistance value and the capacitance value of a normal person to determine whether it is normal and outputting the output to the output unit. Ion and viscosity state measuring device of blood extracted from the living body.
KR1020100130050A 2010-12-17 2010-12-17 Device for measuring blood ion and viscosity state KR20120068430A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020100130050A KR20120068430A (en) 2010-12-17 2010-12-17 Device for measuring blood ion and viscosity state

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020100130050A KR20120068430A (en) 2010-12-17 2010-12-17 Device for measuring blood ion and viscosity state

Publications (1)

Publication Number Publication Date
KR20120068430A true KR20120068430A (en) 2012-06-27

Family

ID=46687114

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020100130050A KR20120068430A (en) 2010-12-17 2010-12-17 Device for measuring blood ion and viscosity state

Country Status (1)

Country Link
KR (1) KR20120068430A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017133918A (en) * 2016-01-27 2017-08-03 国立大学法人九州工業大学 Body fluid viscosity measurement device
US9763595B2 (en) 2014-01-21 2017-09-19 Samsung Electronics Co., Ltd. Apparatus and method of measuring bio impedance
WO2019016570A1 (en) * 2017-07-20 2019-01-24 Viscgo Limited Device, fluid testing kit and uses thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9763595B2 (en) 2014-01-21 2017-09-19 Samsung Electronics Co., Ltd. Apparatus and method of measuring bio impedance
JP2017133918A (en) * 2016-01-27 2017-08-03 国立大学法人九州工業大学 Body fluid viscosity measurement device
WO2019016570A1 (en) * 2017-07-20 2019-01-24 Viscgo Limited Device, fluid testing kit and uses thereof
JP2020527732A (en) * 2017-07-20 2020-09-10 ヴィスクゴー リミテッド Devices, fluid test kits and their use

Similar Documents

Publication Publication Date Title
AU2012385950B2 (en) System and method for detecting used and dried sensors
CN104697917B (en) The impedance bioelectrical measurement system anomaly detection method and system combined based on multiple features
JP5450590B2 (en) Operating method of apex position specifying device and apex position specifying device
RU2010150169A (en) PROBE MAPPING WITH THE PROBE USING CONTACT INFORMATION
CN105559941B (en) Measure the gel film capacitive array sensor and method of full denture dynamic engagement
US20010027275A1 (en) Apparatus and method for measuring the moisture level within enamel dentine or tooth tissue
CN102879442A (en) Graphene quantum dot modified electrochemical sensor, and preparation method and application thereof
KR20120068430A (en) Device for measuring blood ion and viscosity state
JP2013537315A (en) Apparatus and method for improved measurement of monitoring apparatus
JP2010172543A (en) Method of estimating percutaneous water transpiration quantity and skin barrier function evaluating device
KR20170135368A (en) Method of blood glucose measurement by using Non-invasive blood glucose meter with momentum measurement function
CN204514850U (en) A kind of galvanochemistry the cannot-harm-detection device detecting cracks of metal surface
TW201313196A (en) Body-type physiological parameters monitoring apparatus and display-switching method and device thereof
CN106901692A (en) Virtual reality device
Soi et al. Electronic apex locators
CN100515363C (en) Root canal length measuring instrument
CN2899732Y (en) Detector for tooth root canal length
JP2017538942A5 (en)
Cheng et al. Towards wearable capacitive sensing of physiological parameters
CN104764771A (en) Potential difference ionic concentration measurement method
CN204330661U (en) A kind of semiconductor gas sensor
CN206339516U (en) A kind of measuring electrode and detection means for being used to detect serotonin
WO2008137529A3 (en) Method and apparatus for detecting arrhythmias in a medical device
CN106353391A (en) Method for quickly determining vitamin C
JP2003310567A (en) Apparatus for measuring barrier function of skin horny layer

Legal Events

Date Code Title Description
N231 Notification of change of applicant
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application