KR20110009411A - A stent expanding vascular and the making method for the stent - Google Patents

Abstract

PURPOSE: A stent for inner cavity expansion is provided, which can prevent foreign material including fine dust from being adsorbed to a stent. CONSTITUTION: A stent for inner cavity expansion comprises: an encapsulation stent having a covering layer(6) or an extension coating stent; and a polymer coating layer(10) in which poly-para-xylylene is coated on the covering layer of the encapsulation stent or extension coating stent into a polymer shape. The polymer coating layer changes di-para-xylylene into para-xylylene and is coated on a covering layer.

Description

INSTANT EXPANDING VASCULAR AND THE MAKING METHOD FOR THE STENT}

The present invention relates to a stent for expanding the lumen used for stenosis narrowing of the lumen due to esophageal cancer or the like and for the smooth supply of bile supplied from the liver.

In general, the stent is a medical device used to expand the lumen by treating the lumen when the lumen in the human body is narrowed by various diseases occurring in the human body to decrease its own function.

This stent is a so-called Wall Type stent shown in US Pat. No. 4.655.771, which has the flexibility of self-expansion and is highly adaptable even when applied to narrow lumens or blood vessels and bent lumens or vessels. Since the length changes at the time of contraction, there is a problem of narrowing the diameter in the bent lumen.

In addition, Republic of Korea Patent No. 0240832, Republic of Korea Patent No. 0193269, Republic of Korea Patent No. 0170219, Republic of Korea Patent No. 0170220, Republic of Korea Patent No. 1999-85314 and Republic of Korea Patent No. 1999-9743 and the Republic of Korea by the inventor of the present invention Korean Patent Publication No. 1998-33463, US Patent No. 6,027,525, including Patent No. 189094.

The above-described stents are different from each other in the method of manufacturing and the shape thereof, but they are all hollowed out by the method of crossing each other or moving them zigzag by using shape memory alloy wire having the property of remembering its own shape. They have the same identity in that they are formed in the shape of a cylindrical body.

In the case of the above-described stents, since the hollow cylindrical bodies constituting the stent are all manufactured by crossing or zigzag the wires of one or two strands, the surface of the stent, that is, the accompanying drawings. As shown in FIGS. 1 and 2, since there is a space portion 1 communicating with the inside of the stent 2, when the stent 2 is treated in the esophagus or bile duct, the narrowed portion is initially removed. By extending it, it is possible to achieve the desired purpose smoothly.

However, as time passes, the masses or debris generated in the lumen penetrate into the interior 3 of the stent 2 through the space 1 of the stent 2, and thus may vary according to the size of the disease. But there is a problem that needs to be reprocessed.

In other words, there is a problem that can not fundamentally block the disease element penetrating into the interior (3) of the stent (2).

In order to solve this problem, there are U.S. Patent Nos. 5,545,211 and 5,330,500, which are summarized as follows.

That is, as shown in Figure 3 attached to the outer surface of the stent (2), a coating made of a polyurethane material is formed, which is made of a polyurethane material on the outer surface of the stent (2) Since the coating layer 4 is formed, it is possible to prevent the penetration of tumors and the like occurring outside of the treated stent when it is applied to the lumen or the like.

In addition, such a coating layer uses a material that is harmless to the human body, including a polyurethane material as well as a silicon material.

This coating layer is not only a stent (2) having a straight structure as described above, but also shown in Figure 4, the stent (5) having a dumbbell structure having an extension part 5 on the upper and lower, as shown in FIG. The coating layer 4 is formed using not only the polyurethane material but also a silicone material, and the human body is treated according to its purpose.

Such stents are also called film forming stents (6) or expanded coating stents (7), depending on their structure.

Each of these stents is inserted into the inserter 8, and the procedure is performed on the human body. In this case, the stents must be performed in the inserter 8 after the manufacturing process as described above. Therefore, the stent is stored in the inserter 8 while the size of the stent is minimized, that is, the diameter is minimized.

In this case, the film-forming stent 6 or the expandable coating stent 7 has an increased length when the diameter is minimized, and also minimizes the diameter, so that the coating layer 4 coated on the stent is in contact with each other. Particularly, when the process of minimizing the diameter of the stent 7 is performed, wrinkles are necessarily generated as the coating layers 4 are narrowed, and thus, the coating layers 4 are inevitably stored, and the coating layers 4 are formed by the wrinkles. ) Are bonded to each other.

When the coating layer 4 is stored for a long time in the wrinkled state, the coating layer 4 is partially adhered to each other due to an external environment such as external temperature, so that an adhesion phenomenon occurs.

This adhesion phenomenon occurs because of the material properties of the coating layer (4).

After such adhesion phenomenon, the inserter 8 is inserted into the human body at the site of the body to be treated with the film forming stent 6 or the expanded coating stent 7, and then the film forming stent 6 Or expand the coated stent 7 from the inserter 8 to the original shape. The above-described adhesive form allows the encapsulating stent 6 or expandable coated stent 7 to be returned to its original state. There is a problem that does not extend.

In fact, after the long term storage of the above-described film-forming stent (6) or expandable coating stent (7) manufactured by the applicant used the same problem occurs, many problems such as replacing a new product in the process of the procedure I caused it.

The present invention is to solve the problems occurring in the above-described film-forming stent or expandable coating stent.

This problem can be solved by minimizing the diameter of the film forming stent or the expanded coating stent so as to prevent the coating layers coated on the stent from contacting each other even after long term storage in the inserter. In order to achieve the present invention, it was possible to have a polymer coating layer, which is a second coating layer which is excellent in surface lubricity and has no adsorption of oil components and is harmless to the human body, in the coating layer of the above-described film-forming stent or the expanded coating stent.

The stent of the present invention is prevented from adhering to each other because of excellent surface lubricity and hydrophilicity even when the polymer coating layer is in contact with each other, so that the stent can be stored in the inserter for a long time, and since the adsorption of fine dust or oil component is especially produced in a clean room, etc. Since it can effectively prevent the adsorption of fine dust, etc. that can be adsorbed finely, it has the effect of preventing foreign matters, such as the adsorbed fine dust to be adsorbed on the stent so as not to enter the human body during the procedure.

Hereinafter, the present invention will be described with reference to FIGS. 6 and 7.

In the present invention, the coating layer 4 of the film forming stent 6 or the expanded coating stent 7 can be provided with a second coating layer which is excellent in surface lubricity and free from adsorption of oil components without harming the human body.

At this time, in the present invention, poly-para-xylene (Poly) is applied to the film-forming stent (6) or the coating layer (4) of the expandable coating stent (7) using the raw material of di-para-xylene (DI-PARA-XYLYLENE). It was possible by having a polymer coating layer 10 which was coated in the form of a polymer of -para-Xylylene).

That is, when di-para-xylene (DI-PARA-XYLYLENE) is inserted into the evaporator and heated, it is evaporated into the gaseous phase. In this state, when it passes through the pyrolyzer, para-xylene (PARA-XYLYLENE) is returned. Will be converted to.

When para-xylene (PARA-XYLYLENE) converted to the monomer in this state is deposited in a vacuum evaporator to be deposited in a vacuum state, it is converted into a poly-para-Xylylene polymer form.

When chemical vacuum deposition is performed as described above in the state in which the above-described film forming stent 6 or the expanded coating stent 7 is administered to such a vacuum evaporator, the above-described film layer 4 has the poly-para-xylene ( Poly-para-Xylylene) polymer is coated to have a polymer coating layer (10).

That is, the present invention was completed by having a polymer coating layer 10 coated by chemical vacuum deposition of a poly-para-xylene polymer separately on the coating layer 4.

The polymer coating layer 10, that is, poly-para-Xylylene polymer is coated by a polymer reaction chemically deposited on the coating layer 4 in a vacuum state as described above, so that the coating layer 4 It can be coated on all the parts of the, and even if applied to the stent as in the case of the present invention is harmless to the human body, not only does not adversely affect the human body but also excellent surface lubricity and hydrophilic properties so that they do not adhere to each other.

In addition, since there is almost no adsorption of fine dust or oil components, it is possible to effectively prevent the adsorption of fine dust, which can be adsorbed finely even in the case of manufacturing in a clean room, etc., thus preventing foreign substances such as the adsorbed fine dust from being adsorbed on the stent. It also has the advantage of not entering the human body during the procedure.

1 to 4 is a reference diagram showing a conventional stent.

5 is a cross-sectional schematic view of a stent inserter.

6 and 7 is a cross-sectional schematic view of the lumen expanding stent of the present invention.

Description of the Related Art

4: film layer 6: film forming stent

7: expanded coating stent 10: polymer coating layer

Claims (2)

In the film forming stent (6) or the expandable coating stent (7) having the coating layer (4), The coating layer 4 of the film forming stent 6 or the expandable coating stent 7 is coated with poly-para-xylene in a polymer form to have a polymer coating layer 10. Lumen extension stent. In the method of manufacturing the lumen expanding stent by coating the coating layer 4 of the film forming stent (6) or the expanded coating stent (7), When di-para-xylene (DI-PARA-XYLYLENE) is inserted into the evaporator and heated, it is evaporated into the gas phase, and in this state, the pyrolyzer is converted into para-xylene (PARA-XYLYLENE) to be converted into chemicals. Coating the coating layer (4) of the encapsulating stent (6) or expandable coating stent (7) administered to the chemical vacuum evaporator while being converted to a poly-para-Xylylene polymer in a vacuum evaporator. Method for producing a lumen expanding stent, characterized in that to have a polymer coating layer (10) by.

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