KR20110002163A - Health-functional composition containing spice extracts - Google Patents
Health-functional composition containing spice extracts Download PDFInfo
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- KR20110002163A KR20110002163A KR1020090059613A KR20090059613A KR20110002163A KR 20110002163 A KR20110002163 A KR 20110002163A KR 1020090059613 A KR1020090059613 A KR 1020090059613A KR 20090059613 A KR20090059613 A KR 20090059613A KR 20110002163 A KR20110002163 A KR 20110002163A
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
- A23V2200/30—Foods, ingredients or supplements having a functional effect on health
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/20—Natural extracts
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- A23V2250/2112—Curcumin, turmeric
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Abstract
Description
본 발명은 향신료추출물을 함유하는 건강기능성 조성물에 관한 것으로서, 좀 더 구체적으로는 강황추출물과 후추추출물로 구성되는 향신료추출물에 오메가 3 지방산, 비타민, 미네랄, 항산화 영양소, 글루코사민, 홍삼, 알로에 또는 식이섬유와 같은 기능성 원료를 혼합하여, 강황의 다양한 약리 효능은 물론 이러한 효능을 증진시키는 첨가 원료들의 기능성을 발휘할 수 있는 인체에 유익한 건강기능식품으로서의 조성물에 관한 것이다. The present invention relates to a health functional composition containing a spice extract, and more specifically, omega 3 fatty acids, vitamins, minerals, antioxidant nutrients, glucosamine, red ginseng, aloe or dietary fiber in a spice extract composed of turmeric extract and pepper extract. By mixing a functional raw material such as, it relates to a composition as a health functional food that is beneficial to the human body that can exhibit the various pharmacological effects of turmeric as well as the additive raw materials to enhance such efficacy.
최근 우리나라에는 의료 기술의 발달 및 물질적 풍요로 인구의 고령화는 가속화되지만 서구형 질환이 급증하는 경향도 강하여, 웰빙, 로하스 등의 트렌드가 사회적 붐을 이루고 있으며, 건강 예방 및 자가 치료적 관점에서 건강기능식품을 통한 질병 예방의 필요성이 더욱 부각되고 있다. 따라서 전반적인 경기 침체로 가계 경제 및 국민 경제가 위축되어 있는 상황에서도 건강기능식품 시장은 잠재적으 로 고성장이 예상되는 분야라 할 수 있다.In Korea, the aging of the population is accelerating due to the development of medical technology and material abundance, but the Western type of disease is also rapidly increasing, so the trends of well-being, LOHAS etc. are becoming a social boom. The need for disease prevention through food is increasing. Therefore, even if the household economy and the national economy are shrinking due to the overall economic downturn, the health functional food market is expected to have a high growth potential.
사실 그동안 건강기능식품 시장은 불법 유사 건강 식품 및 과대 광고로 인한 소비자 피해 등으로 시장이 성숙되는데 어려움이 있었으나, 최근 개정된 건강기능식품에 관한 법률 등 제도적 정비로 인해 점차 그 상황이 개선되고 있는 실정이다. In fact, the market for dietary supplements has been difficult to mature due to consumer damages due to illegal similar dietary foods and hype, but the situation is gradually improving due to the systematic revision such as the recently amended laws on dietary supplements. to be.
건강기능식품의 원료는 매우 광범위하다. 각종 동식물의 추출물은 물론 식물추출물 발효 제품, 꽃가루 등, 인체에 유용한 기능성을 가진 원료나 성분이 폭넓게 사용된다. The ingredients for dietary supplements are very extensive. As well as extracts of various animals and plants, plant extracts fermented products, pollen, such as raw materials and ingredients that are useful for the human body are widely used.
건강기능식품의 원료로서 최근 향신료의 다양한 기능성이 부각되고 있는데, 이들 중 카레는 강황과 기타 향신료 10~20종을 혼합하여 만든 것으로 세계적으로 가장 유명한 혼합 향신료라 할 수 있다. Recently, various functionalities of spices are highlighted as raw materials of health functional foods. Among them, curry is made by mixing turmeric and 10-20 kinds of spices, which is the most famous mixed spices in the world.
카레의 노란색은 강황의 주요 성분인 커큐미노이드(curcuminoid)라는 노란색 복합 색소성분으로 인한 것이며, 그 중 가장 대표되는 성분이 커큐민(curcumin)이다. Curry yellow is due to a yellow complex pigment called curcuminoid, which is a major component of turmeric, the most representative of which is curcumin.
강황은 생강과(Curcuma longa Linn.)인 다년생 허브의 뿌리줄기를 말하며, 열대 아시아가 원산지인 식물이다. 동아시아에서는 의약 용도로 널리 사용되어 왔으며, 세계적으로 천연 색소, 향신료 및 민간 치료제로 사용되어 왔다. 우리나라에서는 특히 카레로 많이 이용되는데, 다른 나라에서는 캔 음료, 유제품, 아이스크림, 요거트, 옐로우 케익, 오렌지주스, 비스킷 등 다양한 종류의 음식에서 활용되고 있다 한다. 인도에서는 전통적으로 상처 부위의 소독이나 알러지 및 염증 등의 치료 요법에 사용되었고, 일본에서는 예로부터 간장의 특효약으로 사용되어 왔다. 한방에서는 어혈을 제거하는 작용이 강해 생리통을 완화시키고, 간기능 장애로 옆구리가 아픈 것을 제거하며, 종기의 초기 증상에 소염, 진통효과가 있으며, 항생, 항암, 소염의 특성과 함께 관절염 치료 및 예방에 사용된 기록이 전해진다. Turmeric refers to the rhizome of perennial herb, Curcuma longa Linn. , Which is native to tropical Asia. In East Asia, it has been widely used for medicinal purposes and has been used worldwide as a natural pigment, spice and folk remedy. In Korea, it is especially used as curry. In other countries, it is used in various kinds of food such as cans, dairy products, ice cream, yoghurt, yellow cakes, orange juice, biscuits. In India, it has traditionally been used for the treatment of wounds, treatments such as allergies and inflammation, and in Japan, it has been used as a special medicine for liver. In oriental medicine, the effect of removing blood is strong, so as to relieve menstrual pain, remove side pain due to liver function disorder, anti-inflammatory and analgesic effect on early symptoms of boil, and anti-arthritis treatment and prevention with the characteristics of antibiotic, anti-cancer, anti-inflammatory The records used in the book are transmitted.
또한 혈액 순환을 촉진하는 역할을 하여 어깨 관절통을 비롯한 타박상이나 어혈 치료제로도 사용되고, 혈중 콜레스테롤 강하작용 및 간 내 바이러스에 대한 억제 작용을 하는 것으로도 알려져 있다. 중국 '중약대사전'을 펼쳐보면 '이담작용이 있는 간장약'이라고 나와 있다. In addition, it serves to promote blood circulation and is also used as a bruise or fish blood treatment, including shoulder joint pain, and is known to have a blood cholesterol lowering effect and an inhibitory effect on liver virus. If you unfold the Chinese medicinal dictionary, it is said that it is a soy sauce medicine with a diarrhea effect.
20세기 들어 동아시아 뿐만 아니라 서양에서도 강황의 약리작용에 대한 관심이 증가하여, Wall Street Journal에 따르면 2005년 커큐민에 관한 연구가 급증하였다고 하였으며 이에 따라 2005년 강황 영양보충제의 판매량이 2004년에 비해 35%나 증가되었다고 하였다. Interest in turmeric's pharmacological activity has increased in the West as well as in East Asia in the 20th century. According to the Wall Street Journal, research on curcumin increased dramatically in 2005, and sales of turmeric supplements in 2005 were 35% higher than in 2004. I have increased.
일본에서 울금은 1998년 붐을 이루면서 시장이 확대되어, 숙취 해소, 간기능 회복의 대표 소재로 중장년층 남성 고객을 중심으로 건강식품 시장을 형성해 오던 것이 최근에는 젊은층과 여성층을 대상으로 한 노화방지식품 및 미용식품 등 다양한 분야에 활용되고 있다.In 1998, turmeric became a boom in Japan, and the market was expanding, and as a representative material for relieving hangovers and restoring liver function, the health food market has been formed mainly among middle-aged male customers. It is used in various fields such as beauty foods.
염색에 사용되기도 하는 강황의 노란색은 커큐미노이드(curcuminoid)라는 색소 때문이다. 이 물질은 커큐민(curcumin), 비스디메톡시 커큐민(bisdemethoxy curcumin), 디메톡시 커큐민(demethoxy curcumin) 3종의 화합물을 통칭한다. 이 중 강황 커큐미노이드의 70% 정도를 차지하는 것이 커큐민으로서 강황에 0.5~6% 정도 함유되어 있다. 그 외에도 강황에는 각종 정유 성분, 칼슘, 철, 마그네슘, 인, 칼 륨, 아연, 비타민 B 1, B2, B3, C 등이 함유되어 있다. The yellow color of turmeric, which is also used for dyeing, is due to a pigment called curcuminoid. This substance collectively refers to three compounds: curcumin, bisdemethoxy curcumin, and demethoxy curcumin. Curcumin, which accounts for about 70% of turmeric curcuminoids, contains about 0.5 to 6% of turmeric. In addition, turmeric contains various essential oils, calcium, iron, magnesium, phosphorus, calcium, zinc, vitamins B 1 , B 2 , B 3 and C.
KBS 생로병사의 비밀에서는 커큐민을 건강의 황금 열쇠라 비유하기도 하였다. 강황 및 강황에 함유된 커큐민은 항산화, 항암, 항염/항관절염, 항바이러스, 치매 예방, 간기능 개선 및 알코올 분해 촉진, 콜레스테롤 저하, 위장질환 개선, 다이어트 등 다양한 약리작용을 지니며, 이러한 약리작용의 대부분은 항산화 작용에서 기인하는 것으로 알려져 있다. The secret of KBS Reproductive Soldiers even compared curcumin as the golden key to health. Curcumin contained in turmeric and turmeric has various pharmacological actions such as antioxidant, anticancer, anti-inflammatory / anti-arthritis, anti-viral, dementia prevention, liver function and alcohol breakdown, cholesterol reduction, gastrointestinal disease, diet, etc. Most of them are known to be due to antioxidant activity.
그러나 자가치료적인 관점에서 환자들이 임의로 강황 및 커큐민을 다량 섭취하는 것은 부작용을 유발할 수 있으므로 바람직하지 못하며, 국제적으로 강황의 주요 성분인 커큐민의 1일 섭취 허용량은 체중 kg당 0~3mg으로 정해져 있다. However, from the self-treatment point of view, it is not preferable that patients ingest a large amount of turmeric and curcumin because it may cause side effects, and the internationally accepted daily intake amount of curcumin, which is a major component of turmeric, is 0 to 3 mg / kg body weight.
커큐민은 인체내 이용률이 매우 낮은 지용성 물질이지만, 후추에 함유된 피페린(piperine) 성분을 함께 섭취할 경우 커큐민의 흡수 효율이 상당히 증가하게 된다. Curcumin is a fat-soluble substance with very low utilization in the human body, but the intake efficiency of curcumin can be significantly increased by ingesting piperine in the pepper.
상기와 같이 강황이나 커큐민의 다양한 약리작용이 알려졌음에도 불구하고, 현재까지 강황추출물과 후추추출물을 이용한 건강식품 및 건강기능식품은 알려지지 않고 있다. Although various pharmacological actions of turmeric and curcumin are known as described above, the health foods and functional foods using turmeric extract and pepper extract are not known to date.
이에 본 발명자는 약용 및 식용으로 널리 사용되어 온 강황과 후추를 이용한 향신료 추출물을 기본 성분으로 하여 각종 기능성 원료와 혼합한 건강기능성 혼합 조성물에 관한 조사 및 연구를 거듭한 결과 강황추출물과 후추 추출물, 그리고 기능성 원료들의 적정 혼합 비율을 제안함으로써 본 발명을 완성하게 되었다. Accordingly, the present inventors have conducted research and research on the health functional mixed composition mixed with various functional raw materials, using the spice extract using turmeric and pepper which have been widely used for medicinal and edible results, and the turmeric extract and pepper extract, and The present invention has been completed by suggesting an appropriate mixing ratio of functional raw materials.
본 발명의 목적은 강황추출물과 후추추출물로 구성되는 향신료추출물에 오메가 3 지방산, 비타민, 미네랄, 항산화 영양소, 글루코사민, 홍삼, 알로에 또는 식이섬유와 같은 기능성 원료를 혼합하여, 강황의 다양한 약리 효능은 물론 이러한 효능을 증진시키는 첨가 원료들의 기능성을 발휘할 수 있는, 인체에 유익한 건강기능식품으로서의 조성물을 제공하는 것이다. An object of the present invention is to mix the functional raw materials such as omega 3 fatty acids, vitamins, minerals, antioxidant nutrients, glucosamine, red ginseng, aloe or dietary fiber to the spice extract composed of turmeric extract and pepper extract, as well as various pharmacological effects of turmeric It is to provide a composition as a health functional food that is beneficial to the human body that can exhibit the functionality of the additive raw materials to enhance such efficacy.
즉, 본 발명은 강황의 주요 성분인 커큐민의 체내 이용률을 높이기 위해 피페린을 혼합하는 것을 기본으로 하여, 이 향신료추출물에 오메가 3 지방산, 비타민 및 미네랄, 항산화 영양소(비타민 C, E, Se), 글루코사민, 홍삼 또는 알로에 등을 혼합하여 커큐민의 효능을 극대화할 수 있는 건강기능식품을 제공함을 목적으로 한다. That is, the present invention is based on mixing pipelin to increase the utilization of curcumin, the main component of turmeric in the body, omega 3 fatty acids, vitamins and minerals, antioxidant nutrients (vitamin C, E, Se), Glucosamine, red ginseng or aloe and the like to provide a health functional food that can maximize the efficacy of curcumin.
상기한 바의 목적을 달성하기 위한 본 발명의 건강기능성 조성물은 80.0~99.9 중량%의 강황추출물(커큐민 순도 70% 이상)과 0.1~20 중량%의 후추추출물(피페린 순도 95% 이상)로 구성되는 향신료추출물을 포함하는데, 이것의 1일 섭취량은 42~305mg인 것이 바람직하다. Health functional composition of the present invention for achieving the above object is composed of 80.0 ~ 99.9% by weight turmeric extract (curcumin purity of 70% or more) and 0.1-20% by weight of pepper extract (pipelin purity of 95% or more) It includes a spice extract, the daily intake of this is preferably 42 ~ 305mg.
상기 향신료추출물의 효능을 극대화하기 위해 본 발명의 건강기능성 조성물은 상기 향신료추출물 1~51 중량부에 오메가 3 지방산, 비타민, 미네랄, 항산화 영 양소, 글루코사민, 홍삼, 알로에 및 식이섬유로 구성되는 군으로부터 선택된 1 이상의 기능성 원료를 34~122 중량부 혼합하여 포함하는 것을 특징으로 한다. In order to maximize the efficacy of the spice extract of the health functional composition of the present invention from 1 to 51 parts by weight of the spice extract from the group consisting of omega 3 fatty acids, vitamins, minerals, antioxidant nutrients, glucosamine, red ginseng, aloe and dietary fiber 34 to 122 parts by weight of the selected one or more functional raw materials, characterized in that it comprises a mixture.
상기 향신료추출물에 대한 상기 기능성 원료의 최적 혼합비는 구체적인 기능성 원료에 따라 다를 수 있다.The optimum mixing ratio of the functional raw material to the spice extract may vary depending on the specific functional raw material.
먼저, 상기 향신료추출물에 오메가 3 지방산을 혼합할 경우 향신료추출물 1~25 중량부에 오메가 3 지방산 75~99 중량부를 포함하는 것이 바람직하다. 상기 오메가 3 지방산은 혈중 중성지질을 개선하고 혈행을 개선하여 강황추출물의 흡수 및 기능을 향상시키며, 오메가 3 지방산의 종류로는 DHA로 알려진 도코사헥사에노산(docosahexaenoic acid)와 EPA로 알려진 에이코사펜타에노산(eicosapentaenoic acid) 등이 있다.First, when the omega 3 fatty acid is mixed with the spice extract, it is preferable to include 75 to 99 parts by weight of the omega 3 fatty acid in 1 to 25 parts by weight of the spice extract. The omega 3 fatty acids improve the neutral lipids in the blood and improve blood circulation to improve the absorption and function of turmeric extract, and the types of omega 3 fatty acids docosahexaenoic acid known as DHA and Eicosa known as EPA Pentaenoic acid (eicosapentaenoic acid).
또, 상기 향신료추출물에 비타민과 미네랄을 혼합할 경우 향신료추출물 20~30 중량부에 비타민으로서 비타민 B1 0.1~0.5 중량부, 비타민 B2 0.1~0.5 중량부, 비타민 B6 0.1~0.5 중량부, 비타민 C 30~60 중량부, 비타민 D 0.1~0.5 중량부, 비타민 E 3~8 중량부를, 미네랄로서 산화아연 0.5~3 중량부, 파라다이스넛 추출분말 6~10 중량부, 어골 분말 10~30 중량부, 산화마그네슘 3~7 중량부, 황산망간 0.5~2 중량부를 혼합하는 것이 바람직하다. 상기에서 파라다이스넛 추출분말은 Se 보충제이고, 어골 분말은 칼슘 보충제라 할 수 있다.In addition, in the case of mixing vitamins and minerals in the spice extracts 20 to 30 parts by weight of spice extracts, vitamin B 1 0.1 to 0.5 parts by weight, vitamin B 2 0.1 to 0.5 parts by weight, vitamin B 6 0.1 to 0.5 parts by weight, 30 to 60 parts by weight of vitamin C, 0.1 to 0.5 parts by weight of vitamin D, 3 to 8 parts by weight of vitamin E, 0.5 to 3 parts by weight of zinc oxide as a mineral, 6 to 10 parts by weight of paradise nut extract powder, 10 to 30 parts by weight of fish bone powder It is preferable to mix 3-7 weight part of magnesium oxides, and 0.5-2 weight part of manganese sulfates. Paradise nut extract powder in the above is Se supplement, fish bone powder may be referred to as calcium supplement.
또한, 상기 향신료추출물에 항산화 영양소를 혼합할 경우 40~51 중량부의 향신료추출물에 30~50 중량부의 비타민 C, 3~10 중량부의 비타민 E, 1~5 중량부의 파 라다이스넛 추출분말을 혼합하는 것이 바람직하다. In addition, when the antioxidant nutrients are mixed with the spice extracts, 30 to 50 parts by weight of vitamin C, 3 to 10 parts by weight of vitamin E, and 1 to 5 parts by weight of Paradise nut extract powder are mixed with 40 to 51 parts by weight of spice extracts. It is preferable.
글루코사민을 혼합할 경우 1~30 중량부의 향신료추출물에 70~99 중량부의 글루코사민을 혼합하는 것이 바람직하다. 글루코사민은 관절 건강에 효능을 가지므로 강황추출물의 관절 건강 기능을 향상시킨다.When glucosamine is mixed, it is preferable to mix 70 to 99 parts by weight of glucosamine with 1 to 30 parts by weight of spice extract. Glucosamine is effective for joint health and therefore improves joint health function of turmeric extract.
홍삼을 혼합할 경우 15~30 중량부의 향신료추출물에 60~90 중량부의 홍삼 분말을 혼합하는 것이 바람직하다. 홍삼은 기본적으로 인체의 면역력을 증진시키고 피로회복 효능을 가지며, 강황추출물의 기능을 향상시켜 강황추출물과의 상승 효과를 극대화할 수 있다.When mixing red ginseng, it is preferable to mix 60 to 90 parts by weight of red ginseng powder with 15 to 30 parts by weight of spice extract. Red ginseng basically enhances the immune system of the human body, has a fatigue recovery effect, and improves the function of turmeric extract to maximize the synergistic effect with turmeric extract.
마지막으로, 알로에 및 식이섬유를 혼합할 경우 3~10 중량부의 향신료추출물에 60~90 중량부의 알로에 및 5~20 중량부의 식이섬유를 혼합하는 것이 바람직하다. 상기 알로에 및 식이섬유는 장 활동을 원활히 하여 체지방 및 체중 감소 효과를 지닌 강황추출물의 기능을 향상시킬 수 있다.Finally, when mixing aloe and dietary fiber, it is preferable to mix 60 to 90 parts by weight of aloe and 5 to 20 parts by weight of dietary fiber to 3 to 10 parts by weight of spice extract. The aloe and dietary fiber can improve the function of turmeric extract having a smooth body activity and weight loss effect.
본 발명의 건강기능성 혼합 조성물을 구성하는 각 성분들에 관한 좀 더 상세한 설명은 다음과 같다. A more detailed description of each component constituting the health functional mixture composition of the present invention is as follows.
먼저 향신료추출물은 강황추출물과 후추추출물로 구성되며, 강황추출물은 강황을 건조하여 분말화한 강황분을 아세톤, 헥산, 에탄올, 메탄올, 초산에틸, 에틸 에테르, 또는 이들 중 하나 이상을 혼합한 유기 용매로 추출 및 정제하여 커큐민 함량 70% 이상이면서 커큐미노이드 함량 95% 이상을 갖도록 제조한 것이다. 본 발명에서 커큐민 함량이 높은 강황추출물을 이용하는 이유는 강황의 대표적 유효 성분 중 하나인 커큐미노이드의 효능을 집약적인 형태로 얻기 위해서이다. First, the spice extract is composed of turmeric extract and pepper extract, and the turmeric extract is an organic solvent obtained by mixing turmeric powder powdered by drying turmeric with acetone, hexane, ethanol, methanol, ethyl acetate, ethyl ether, or one or more of them. Extracted and purified with a curcumin content of 70% or more and prepared to have a curcuminoid content of 95% or more. The reason for using turmeric extract with high curcumin content in the present invention is to obtain the efficacy of curcuminoids, one of the representative active ingredients of turmeric, in intensive form.
후추추출물은 커큐민의 체내 이용률을 높이기 위해 혼합하는 것으로, 후추를 상기 유기 용매로 추출 및 정제하여 피페린 함량이 95% 이상이 되도록 제조한 것이다. The pepper extract is mixed to increase the utilization of curcumin in the body, and the pepper is extracted and purified with the organic solvent to prepare a pipelin content of 95% or more.
오메가 3 지방산은 오메가 3 지방산을 함유한 유지로서 식용 가능한 어류, 바닷물범, 조류 등으로부터 얻어지며, 가열, 압착, 및 헥산을 이용하거나 초임계 추출법으로 추출하여 여과된 것으로 EPA와 DHA 함량이 합계 120~300mg 이상 함유된 것을 사용한다. Omega 3 fatty acids are oils containing omega 3 fatty acids, which are obtained from edible fish, sea seals, algae, etc., and are filtered by heating, pressing, hexane, or extracted by supercritical extraction. Use more than ~ 300mg.
비타민 및 미네랄 혹은 항산화 영양소 중 먼저 비타민 D는 비타민 D2 혹은 D3를 사용하며, 비타민 E는 D-알파 토코페롤, DL-알파-토코페롤, DL-알파-토코페릴 초산염 등을 사용한다. 비타민 B1은 비타민 B1 염산염을, 비타민 B2는 그 자체를, 나이아신은 니코틴산이나 니코틴산아미드를, B6는 피리독신염산염을, 비타민 C는 L-아스코르빈산나트륨을, 마그네슘은 산화마그네슘을, 아연은 산화아연을, 망간은 황산망간을 사용한다. 파라다이스넛 추출분말은 셀렌을 보충하기 위해, 어골 분말은 칼슘을 보충하기 위해 혼합한다.Among vitamins, minerals and antioxidants, vitamin D uses vitamin D2 or D3, and vitamin E uses D-alpha tocopherol, DL-alpha-tocopherol, DL-alpha-tocopheryl acetate, and the like. Vitamin B 1 is vitamin B 1 hydrochloride, vitamin B 2 is itself, niacin is nicotinic acid or nicotinamide, B 6 is pyridoxine hydrochloride, vitamin C is sodium L-ascorbate, magnesium is magnesium oxide, Zinc uses zinc oxide and manganese manganese sulfate. Paradise nut extract powder is mixed to replenish selenium and fish bone powder to replenish calcium.
글루코사민은 갑각류(게, 새우 등)의 껍질 혹은 연체류(오징어, 갑오징어 등)의 뼈, Aspergillus niger 등으로부터 추출한 것으로 글루코사민 염산염 혹은 글루코사민 황산염의 형태로 사용한다. Glucosamine is extracted from shells of shellfish (crabs, shrimp, etc.) or bones of molluscs (squids, cuttlefish, etc.) and Aspergillus niger, and is used in the form of glucosamine hydrochloride or glucosamine sulfate.
홍삼은 인삼 혹은 수삼을 증기 또는 기타 방법으로 쪄서 익혀 말린 것을 사용하여 물이나 주정으로 추출하여 여과하거나, 여과 후 농축 또는 발효한 것을 사 용한다. Red ginseng is steamed or steamed with ginseng or fresh ginseng, dried and then extracted with water or alcohol, filtered, concentrated or fermented after filtration.
알로에는 알로에 베라, 알로에 에보레센스, 알로에 사포나리아의 잎을 원료로 하여 비가식 부분을 제거한 후 건조 및 분말화한 것과 알로에 베라 잎의 겔 부위를 분리하여 건조 및 분말화한 것을 사용하며, 식이섬유로는 차전자 껍질을 분쇄한 차전자피를 사용한다. Aloe is a leaf of aloe vera, aloe eboresens and aloe saponaria, dried and powdered after removing the non-edible portion, and dried and powdered by separating the gel portion of the aloe vera leaf. As the dietary fiber, the chaff shells obtained by crushing the chariot shells are used.
상기에서 살펴본 바와 같이 본 발명의 건강기능성 조성물은 강황추출물과 후추추출물로 구성된 향신료추출물을 기본으로 하는 혼합물로서, 강황 및 그 유효성분인 커큐민은 항산화, 항암, 항염/항관절염, 항바이러스, 치매예방, 간기능 개선 및 알코올 분해 촉진, 콜레스테롤 저하, 위장질환 개선, 다이어트 등 다양한 약리작용을 지닌 물질이다. 또한 후추의 성분인 피페린은 커큐민의 체내 흡수율을 증가시키기 위한 유효 성분이다.As described above, the health functional composition of the present invention is a mixture based on a spice extract composed of turmeric extract and pepper extract, and turmeric and its active ingredient curcumin are antioxidant, anticancer, anti-inflammatory / antiarthritis, antiviral, and dementia prevention. It is a substance with various pharmacological actions such as improving liver function and promoting alcohol degradation, lowering cholesterol, improving gastrointestinal diseases, and diet. Pepperin, a component of pepper, is an active ingredient for increasing the absorption rate of curcumin in the body.
또한 혈중 중성지질 개선 및 혈행개선에 도움을 주는 오메가 3 지방산, 각종 영양보충 기능을 지닌 비타민 및 미네랄, 항산화 효능을 지닌 비타민 C, E, 그리고 셀렌, 관절 건강에 도움을 주는 글루코사민, 면역력 증진, 피로회복 효능을 지닌 홍삼, 배변활동을 돕는 알로에 및 식이섬유는, 상기 향신료추출물과 혼합하여 본 발명의 건강기능성 혼합 조성물을 구성함으로써 상기 강황의 기능성을 향상시키는 역할을 한다. In addition, omega 3 fatty acids help improve triglycerides and improve circulation in the blood, vitamins and minerals with various nutritional supplements, vitamins C and E with antioxidant properties, and selenium, glucosamine for joint health, immune system, and fatigue Red ginseng having a restorative effect, aloe and dietary fiber to help defecation activity, by mixing with the spice extract to form a health functional mixed composition of the present invention serves to improve the functionality of the turmeric.
본 발명의 건강기능성 조성물은 어떠한 제형으로 제조하여도 무방하다. 즉, 정제, 캡슐, 분말, 용액, 젤, 페이스트, 과립, 환 등으로 제조될 수 있다. The health functional composition of the present invention may be prepared in any formulation. That is, it can be prepared into tablets, capsules, powders, solutions, gels, pastes, granules, pills, and the like.
본 발명의 건강기능성 혼합 조성물의 제형화를 위해 이용 가능한 기타 첨가 물은 당업자에게 이미 주지되어 있으며, 당업자가 용이하게 선택할 수 있는 각종 부형제, 담체 또는 희석제를 포함할 수 있다. Other additives available for the formulation of the health functional mixed composition of the present invention are well known to those skilled in the art and may include various excipients, carriers or diluents which can be readily selected by those skilled in the art.
상기 본 발명의 건강기능성 혼합 조성물에서 각 성분들의 함량비는 의도하는 효과를 달성하기 위한 최적의 비율로서 선택된 것이다. The content ratio of each component in the health functional mixture composition of the present invention is selected as the optimum ratio for achieving the intended effect.
즉, 강황추출물과 후추추출물의 비율, 커큐민과 피페린의 비율, 그리고 강황추출물과 후추추출물의 혼합물인 향신료추출물의 1일 제공량 및 기능성 원료인 오메가 3 지방산, 비타민 및 미네랄, 항산화 영양소(비타민 C, E, 셀렌), 글루코사민, 홍삼, 알로에 및 식이섬유의 비율은 지정된 상기 수치 범위를 만족할 경우 강황 커큐민의 흡수율을 향상시켜 인체에 대한 유익한 기능성을 극대화할 수 있다. That is, the ratio of turmeric extract and pepper extract, the ratio of curcumin and piperine, and the daily serving amount of spice extract, which is a mixture of turmeric extract and pepper extract, omega 3 fatty acids, vitamins and minerals, and antioxidant nutrients (vitamin C, E, selenium), glucosamine, red ginseng, aloe and the ratio of dietary fiber can maximize the beneficial functionality to the human body by improving the absorption rate of turmeric curcumin when the specified numerical range is satisfied.
본 발명의 건강기능성 혼합 조성물은 향신료추출물을 기본 성분으로 하며, 향신료추출물의 유효량은 하루에 42~305 mg(커큐민 함량 30~180 mg, 피페린 함량 0.3~1.8 mg)이 바람직하다. The health functional mixed composition of the present invention is based on the spice extract, the effective amount of the spice extract is preferably 42 ~ 305 mg (curcumin content 30 ~ 180 mg, piperine content 0.3 ~ 1.8 mg) per day.
또는 향신료추출물을 함유하는 건강기능성 혼합 조성물을 하루에 0.5~10g 섭취하는 것이 바람직하다. Or it is preferable to ingest 0.5 ~ 10g per day of a health functional mixed composition containing a spice extract.
더 바람직하게는 향신료추출물로서 120~180 mg, 혹은 향신료추출물을 함유한 건강기능성 혼합 조성물을 1~2g 섭취하는 것이다. More preferably 120 to 180 mg, or as a spice extract is to intake 1-2g of the health functional mixed composition containing a spice extract.
구체적인 실제 섭취량은 섭취 대상자의 연령, 성별, 체중 및 질병 유무를 고려하여 결정되어야 하는 것으로 이해되어야 하며, 상기 섭취량은 어떠한 면으로든 본 발명의 범위를 한정하는 것은 아니다. It is to be understood that the specific actual intake should be determined in consideration of the age, sex, weight, and disease presence of the intake subject, and the intake does not limit the scope of the present invention in any aspect.
본 발명에 의하면, 강황추출물과 후추추출물로 구성되는 향신료추출물에 오메가 3 지방산, 비타민, 미네랄, 항산화 영양소, 글루코사민, 홍삼, 알로에 또는 식이섬유와 같은 기능성 원료를 혼합하여, 강황의 다양한 약리 효능은 물론 이러한 효능을 증진시키는 첨가 원료들의 기능성을 발휘할 수 있는 인체에 유익한 건강기능식품으로서의 조성물을 제공할 수 있게 된다. According to the present invention, the spice extract composed of turmeric extract and pepper extract is mixed with functional raw materials such as omega 3 fatty acids, vitamins, minerals, antioxidant nutrients, glucosamine, red ginseng, aloe or dietary fiber, as well as various pharmacological effects of turmeric It is possible to provide a composition as a health functional food that is beneficial to the human body that can exhibit the functionality of the additive raw materials to enhance such efficacy.
이하, 실시예 및 실험예를 들어 본 발명을 상세히 설명하겠지만, 본 발명의 권리범위가 이들 실시예에 의하여 한정되는 것은 아니다. Hereinafter, the present invention will be described in detail with reference to Examples and Experimental Examples, but the scope of the present invention is not limited to these Examples.
[실시예 1] 향신료추출물과 오메가 3 지방산을 함유하는 연질 캡슐 형태의 건강기능성 조성물의 제조Example 1 Preparation of a health functional composition in the form of a soft capsule containing a spice extract and omega 3 fatty acids
1. 제1공정 1. First process
99 중량%의 강황추출물과 1 중량%의 후추추출물을 칭량하여 32mesh로 체과한 후 고속혼합기에 투입 혼합하여 향신료추출물을 제조하였다. 99 wt% turmeric extract and 1 wt% pepper extract were weighed and sieved to 32mesh, and then mixed with a high speed mixer to prepare a spice extract.
2. 제2공정 2. Second process
상기에서 얻어진 향신료추출물 7.5 중량부와 92.5 중량부의 오메가 3 지방산을 투입 혼합하여 본 발명의 건강기능성 조성물을 제조하였다. 7.5 parts by weight of the spice extract and 92.5 parts by weight of the omega 3 fatty acid obtained in the above mixture was prepared to prepare a health functional composition of the present invention.
3. 제3공정 (캡슐 충진)3. Third process (capsule filling)
제2공정에서 얻어진 혼합물을 연질 캡슐 충진기를 통해 연질 캡슐에 충진하였다. The mixture obtained in the second step was filled into soft capsules via a soft capsule filler.
4. 제4공정 (선별)4. 4th process (selection)
상기에서 얻어진 연질 캡슐 중 불량 캡슐제를 골라냈다. The defective capsules were selected from the soft capsules obtained above.
[실시예 2] 향신료추출물과 비타민 및 미네랄을 함유하는 정제 형태의 건강기능성 조성물의 제조Example 2 Preparation of Health Functional Composition in Tablet Form Containing Spice Extract and Vitamins and Minerals
1. 제1공정1. First process
99 중량%의 강황추출물과 1 중량%의 후추추출물을 칭량하여 32mesh로 체과한 후 고속혼합기에 투입 혼합하여 향신료추출물을 제조하였다. 99 wt% turmeric extract and 1 wt% pepper extract were weighed and sieved to 32mesh, and then mixed with a high speed mixer to prepare a spice extract.
2. 제2공정2. Second process
상기에서 얻어진 향신료추출물 25.78 중량부에, 비타민 B1 0.11 중량부, 비타민 B2 0.11 중량부, 비타민 B6 0.11 중량부, 비타민 C 35.8 중량부, 비타민 D 0.25 중량부, 비타민 E 5.4 중량부, 산화아연 1.35 중량부, 파라다이스넛 추출분말 8.95 중량부, 어골분말 14.35 중량부, 산화마그네슘 6.7 중량부, 황산망간 1.2 중량부를 혼합하여 본 발명의 건강기능성 조성물을 제조하였다. 25.78 parts by weight of the spice extract obtained above, 0.11 parts by weight of vitamin B 1, 0.11 parts by weight of vitamin B 2, 0.11 parts by weight of vitamin B 6 , 35.8 parts by weight of vitamin C, 0.25 parts by weight of vitamin D, 5.4 parts by weight of vitamin E, oxidation The health functional composition of the present invention was prepared by mixing 1.35 parts by weight of zinc, 8.95 parts by weight of paradise nut extract powder, 14.35 parts by weight of fish bone powder, 6.7 parts by weight of magnesium oxide, and 1.2 parts by weight of manganese sulfate.
3. 제3공정 (타정) 3. Third process (tableting)
제 2공정에서 얻어진 혼합물을 타정기에서 정제로 제조하였다. The mixture obtained in the second step was prepared as a tablet in a tablet press.
4. 제4공정 (선별)4. 4th process (selection)
상기에서 얻어진 정제를 선별하여 불량 정제를 골라냈다. The tablets obtained above were screened and poor tablets were selected.
[실시예 3] 향신료추출물 및 항산화영양소를 함유하는 정제 형태의 건강기능성 조성물의 제조Example 3 Preparation of Health Functional Composition in Tablet Form Containing Spice Extract and Antioxidant Nutrients
1. 제1공정 1. First process
99 중량%의 강황추출물과 1 중량%의 후추추출물을 칭량하여 32mesh로 체과한 후 고속혼합기에 투입 혼합하여 향신료추출물을 제조하였다. 99 wt% turmeric extract and 1 wt% pepper extract were weighed and sieved to 32mesh, and then mixed with a high speed mixer to prepare a spice extract.
2. 제2공정2. Second process
상기에서 얻어진 향신료추출물 49.83 중량부에 34.6 중량부의 비타민 C, 8.38 중량부의 비타민 E, 4.19 중량부의 파라다이스넛 추출분말을 혼합하여 본 발명의 건강기능성 조성물을 제조하였다. 49.83 parts by weight of the spice extract obtained above was mixed with 34.6 parts by weight of vitamin C, 8.38 parts by weight of vitamin E, and 4.19 parts by weight of paradise nut extract powder to prepare a health functional composition of the present invention.
3. 제3공정 (타정) 3. Third process (tableting)
제2공정에서 얻어진 혼합물을 타정기에서 정제로 제조하였다. The mixture obtained in the second step was prepared as a tablet in a tablet press.
4. 제4공정 (선별)4. 4th process (selection)
상기에서 얻어진 정제를 선별하여 불량 정제를 골라냈다. The tablets obtained above were screened and poor tablets were selected.
[실시예 4] 향신료추출물 및 글루코사민을 함유한 경질캡슐 형태의 건강기능성 조성물의 제조Example 4 Preparation of Health Functional Composition in Hard Capsule Form Containing Spice Extract and Glucosamine
1. 제1공정1. First process
99 중량%의 강황추출분말과 1 중량%의 후추추출물을 칭량하여 32mesh로 체과 한 후 고속혼합기에 투입 혼합하여 향신료추출물을 제조하였다. 99 wt% turmeric extract powder and 1 wt% pepper extract were weighed, sieved to 32mesh, and mixed with a high speed mixer to prepare a spice extract.
2. 제2공정2. Second process
상기에서 얻어진 향신료 추출물 8.5 중량부에 91.5 중량부의 글루코사민을 혼합하여 본 발명의 건강기능성 조성물을 제조하였다. The health functional composition of the present invention was prepared by mixing 91.5 parts by weight of glucosamine with 8.5 parts by weight of the spice extract obtained above.
3. 제3공정 (캡슐) 3. 3rd process (capsules)
제2공정에서 얻어진 혼합물을 경질캡슐 충전기를 통해 경질캡슐로 제조하였다. The mixture obtained in the second step was prepared into hard capsules via a hard capsule filling machine.
4. 제4공정 (선별)4. 4th process (selection)
상기에서 얻어진 캡슐을 선별하여 불량 경질캡슐을 골라냈다. The capsules obtained above were selected to pick out defective hard capsules.
[실시예 5] 향신료추출물과 홍삼을 함유한 과립 형태의 건강기능성 조성물의 제조Example 5 Preparation of Health Functional Composition in Granular Form Containing Spice Extract and Red Ginseng
1. 제1공정 1. First process
99 중량%의 강황추출물과 1 중량%의 후추추출물을 칭량하여 32mesh로 체과한 후 고속혼합기에 투입 혼합하여 향신료추출물을 제조하였다. 99 wt% turmeric extract and 1 wt% pepper extract were weighed and sieved to 32mesh, and then mixed with a high speed mixer to prepare a spice extract.
2. 제2공정2. Second process
상기에서 얻어진 향신료추출물 29.77 중량부에 70.23 중량부의 홍삼분말을 혼합하여 본 발명의 건강기능성 조성물을 제조하였다. The health functional composition of the present invention was prepared by mixing 70.23 parts by weight of red ginseng powder with 29.77 parts by weight of the spice extract obtained above.
3. 제3공정 (과립) 3. 3rd process (granulation)
제2공정에서 얻어진 혼합물을 물(또는 주정)로 과립화하였다.The mixture obtained in the second step was granulated with water (or alcohol).
4. 제4공정 (충진) 4. 4th process (filling)
상기 혼합물을 스틱 형태의 포장재에 충진하였다. The mixture was filled into stick-shaped packaging.
5. 제5공정 (선별)5. 5th process (selection)
상기 제품을 선별하여 불량 생산품을 골라냈다. The product was selected to pick out defective products.
[실시예 6] 향신료추출물과 알로에 및 식이섬유를 함유한 정제 형태의 건강기능성 조성물의 제조Example 6 Preparation of Health Functional Composition in Tablet Form Containing Spice Extract, Aloe and Dietary Fiber
1. 제1공정 1. First process
99 중량%의 강황추출물과 1 중량%의 후추추출물을 칭량하여 32mesh로 체과한 후 고속혼합기에 투입 혼합하여 향신료추출물을 제조하였다. 99 wt% turmeric extract and 1 wt% pepper extract were weighed and sieved to 32mesh, and then mixed with a high speed mixer to prepare a spice extract.
2. 제2공정 2. Second process
상기에서 얻어진 향신료추출물 6.4 중량부에 80 중량부의 알로에 및 13.6 중량부의 식이섬유를 혼합하여 본 발명의 건강기능성 조성물을 제조하였다. 80 parts by weight of aloe and 13.6 parts by weight of dietary fiber were prepared by mixing 6.4 parts by weight of the spice extract obtained above to prepare a health functional composition of the present invention.
3. 제3공정 (타정) 3. Third process (tableting)
제2공정에서 얻어진 혼합물을 타정기를 통해 정제로 제조하였다. The mixture obtained in the second step was prepared into tablets through a tablet press.
4. 제4공정 (선별)4. 4th process (selection)
상기 정제를 선별하여 불량 정제를 골라냈다. The tablets were screened to pick out poor tablets.
Claims (8)
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2019051565A1 (en) * | 2017-09-18 | 2019-03-21 | BH Biotech Pty Ltd | Composition and uses thereof |
| GB2581609A (en) * | 2017-09-18 | 2020-08-26 | BH Biotech Pty Ltd | Composition and uses thereof |
| US11173166B2 (en) | 2017-09-18 | 2021-11-16 | BH Biotech Pty Ltd | Composition and uses thereof |
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