KR20060097028A - Ｅｐ4 수용체 길항제로서 푸란 유도체 - Google Patents
Ｅｐ4 수용체 길항제로서 푸란 유도체 Download PDFInfo
- Publication number
- KR20060097028A KR20060097028A KR1020067009418A KR20067009418A KR20060097028A KR 20060097028 A KR20060097028 A KR 20060097028A KR 1020067009418 A KR1020067009418 A KR 1020067009418A KR 20067009418 A KR20067009418 A KR 20067009418A KR 20060097028 A KR20060097028 A KR 20060097028A
- Authority
- KR
- South Korea
- Prior art keywords
- phenyl
- group
- compound
- acid
- formula
- Prior art date
Links
- 0 CS(NC(*)=O)(=O)=O Chemical compound CS(NC(*)=O)(=O)=O 0.000 description 6
- RSCCTCDXPYWBHW-UHFFFAOYSA-N CCOC(Cc(cc1)ccc1NC(c1c(C)[o]c(-c(cc2)ccc2O)c1)=O)=O Chemical compound CCOC(Cc(cc1)ccc1NC(c1c(C)[o]c(-c(cc2)ccc2O)c1)=O)=O RSCCTCDXPYWBHW-UHFFFAOYSA-N 0.000 description 1
- IQEKFIYOSLBBMJ-UHFFFAOYSA-N CCOC(Cc(cc1)ccc1NC(c1c(C)[o]c(Br)c1)=O)=O Chemical compound CCOC(Cc(cc1)ccc1NC(c1c(C)[o]c(Br)c1)=O)=O IQEKFIYOSLBBMJ-UHFFFAOYSA-N 0.000 description 1
- QORCZLVPGWGQFE-UHFFFAOYSA-N CCOC(Cc(cc1)ccc1NC(c1c[o]c(-c(cc2)ccc2OC(F)F)c1)O)=O Chemical compound CCOC(Cc(cc1)ccc1NC(c1c[o]c(-c(cc2)ccc2OC(F)F)c1)O)=O QORCZLVPGWGQFE-UHFFFAOYSA-N 0.000 description 1
- YQROOKGRFHAYEN-UHFFFAOYSA-N Cc([o]c(Br)c1)c1C(O)=O Chemical compound Cc([o]c(Br)c1)c1C(O)=O YQROOKGRFHAYEN-UHFFFAOYSA-N 0.000 description 1
- HQEFZABRNVWGBR-UHFFFAOYSA-N Cc([o]c(Br)c1)c1C(OC)=O Chemical compound Cc([o]c(Br)c1)c1C(OC)=O HQEFZABRNVWGBR-UHFFFAOYSA-N 0.000 description 1
- MMYRRZGEVDYJRB-UHFFFAOYSA-N Cc(cccc1)c1S(NC(Cc(cc1)ccc1NC(c1c[o]c(-c2ccccc2)c1)=O)=O)(=O)=O Chemical compound Cc(cccc1)c1S(NC(Cc(cc1)ccc1NC(c1c[o]c(-c2ccccc2)c1)=O)=O)(=O)=O MMYRRZGEVDYJRB-UHFFFAOYSA-N 0.000 description 1
- FEXSPVHMOOPIJR-UHFFFAOYSA-N OC(CC1C=CC(NC(c2c[o]c(-c(cc3)ccc3OC(F)F)c2)=O)=CC1)=O Chemical compound OC(CC1C=CC(NC(c2c[o]c(-c(cc3)ccc3OC(F)F)c2)=O)=CC1)=O FEXSPVHMOOPIJR-UHFFFAOYSA-N 0.000 description 1
- DOFJLYRISUOURB-UHFFFAOYSA-N OC(Cc(cc1)ccc1NC(c1c[o]c(-c2ccccc2)c1)=O)=O Chemical compound OC(Cc(cc1)ccc1NC(c1c[o]c(-c2ccccc2)c1)=O)=O DOFJLYRISUOURB-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0324269.0 | 2003-10-16 | ||
| GBGB0324269.0A GB0324269D0 (en) | 2003-10-16 | 2003-10-16 | EP4 receptor antagonists |
| US51220003P | 2003-10-20 | 2003-10-20 | |
| US60/512,200 | 2003-10-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20060097028A true KR20060097028A (ko) | 2006-09-13 |
Family
ID=34466432
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020067009418A KR20060097028A (ko) | 2003-10-16 | 2004-10-15 | Ｅｐ4 수용체 길항제로서 푸란 유도체 |
Country Status (3)
| Country | Link |
|---|---|
| KR (1) | KR20060097028A (no) |
| DE (1) | DE602004018527D1 (no) |
| NO (1) | NO20062187L (no) |
-
2004
- 2004-10-15 KR KR1020067009418A patent/KR20060097028A/ko active IP Right Grant
- 2004-10-15 DE DE602004018527T patent/DE602004018527D1/de active Active
-
2006
- 2006-05-15 NO NO20062187A patent/NO20062187L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20062187L (no) | 2006-07-07 |
| DE602004018527D1 (de) | 2009-01-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR101094003B1 (ko) | Ｅｐ4 수용체 길항제 | |
| US20080306117A1 (en) | Ep4 receptor antagonists | |
| WO2005080367A1 (en) | Ep2 receptor agonists | |
| JP2009505973A (ja) | Ｅｐ２受容体アゴニスト | |
| US7528157B2 (en) | EP4 receptor antagonists | |
| WO2012033195A1 (ja) | 複素環化合物 | |
| JP2008539181A (ja) | Ｅｐ１受容体アンタゴニストとして有用なフラン化合物 | |
| KR20060097028A (ko) | Ｅｐ4 수용체 길항제로서 푸란 유도체 | |
| Clark et al. | EP 4 receptor antagonists | |
| Clark et al. | Furan derivatives as EP 4 receptor antagonists | |
| Oxford et al. | EP 4 receptor antagonists | |
| BRPI0614724A2 (pt) | agonistas de receptor de ep2 | |
| WO2005097113A2 (en) | 5-ht2b receptor antagonists |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| AMND | Amendment | ||
| E902 | Notification of reason for refusal | ||
| E601 | Decision to refuse application | ||
| AMND | Amendment | ||
| J201 | Request for trial against refusal decision | ||
| E902 | Notification of reason for refusal | ||
| B701 | Decision to grant | ||
| NORF | Unpaid initial registration fee |