KR20020019992A - A process for preparing high efficiency food having improved calcium absorption - Google Patents
A process for preparing high efficiency food having improved calcium absorption Download PDFInfo
- Publication number
- KR20020019992A KR20020019992A KR1020000052784A KR20000052784A KR20020019992A KR 20020019992 A KR20020019992 A KR 20020019992A KR 1020000052784 A KR1020000052784 A KR 1020000052784A KR 20000052784 A KR20000052784 A KR 20000052784A KR 20020019992 A KR20020019992 A KR 20020019992A
- Authority
- KR
- South Korea
- Prior art keywords
- calcium
- minerals
- protein
- food
- absorption
- Prior art date
Links
- 239000011575 calcium Substances 0.000 title claims abstract description 26
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title claims abstract description 25
- 229910052791 calcium Inorganic materials 0.000 title claims abstract description 24
- 235000013305 food Nutrition 0.000 title claims abstract description 19
- 238000010521 absorption reaction Methods 0.000 title claims description 18
- 238000004519 manufacturing process Methods 0.000 title claims description 10
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 39
- 239000011707 mineral Substances 0.000 claims abstract description 39
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims abstract description 26
- 102000004169 proteins and genes Human genes 0.000 claims abstract description 18
- 108090000623 proteins and genes Proteins 0.000 claims abstract description 18
- 239000004310 lactic acid Substances 0.000 claims abstract description 13
- 235000014655 lactic acid Nutrition 0.000 claims abstract description 13
- 229910052742 iron Inorganic materials 0.000 claims abstract description 11
- 229910052802 copper Inorganic materials 0.000 claims abstract description 8
- 238000000034 method Methods 0.000 claims abstract description 8
- 108091005804 Peptidases Proteins 0.000 claims abstract description 6
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 6
- 239000000203 mixture Substances 0.000 claims abstract description 5
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 22
- 239000010949 copper Substances 0.000 claims description 8
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 7
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 5
- 239000011701 zinc Substances 0.000 claims description 5
- 102000035195 Peptidases Human genes 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 4
- 229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 claims description 3
- 102000015636 Oligopeptides Human genes 0.000 abstract description 14
- 108010038807 Oligopeptides Proteins 0.000 abstract description 14
- 230000015572 biosynthetic process Effects 0.000 abstract description 3
- 239000004365 Protease Substances 0.000 abstract description 2
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract description 2
- 235000010804 Maranta arundinacea Nutrition 0.000 abstract 2
- 229920002472 Starch Polymers 0.000 abstract 2
- 244000145580 Thalia geniculata Species 0.000 abstract 2
- 235000012419 Thalia geniculata Nutrition 0.000 abstract 2
- 235000019698 starch Nutrition 0.000 abstract 2
- 239000008107 starch Substances 0.000 abstract 2
- 108010009736 Protein Hydrolysates Proteins 0.000 abstract 1
- 239000003531 protein hydrolysate Substances 0.000 abstract 1
- 235000010755 mineral Nutrition 0.000 description 36
- 229960005069 calcium Drugs 0.000 description 18
- 102000004190 Enzymes Human genes 0.000 description 17
- 108090000790 Enzymes Proteins 0.000 description 17
- 229940088598 enzyme Drugs 0.000 description 16
- 150000002500 ions Chemical class 0.000 description 10
- 238000006243 chemical reaction Methods 0.000 description 7
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- 235000021321 essential mineral Nutrition 0.000 description 3
- 239000003925 fat Substances 0.000 description 3
- 239000003446 ligand Substances 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- 102000004196 processed proteins & peptides Human genes 0.000 description 3
- 108090000765 processed proteins & peptides Proteins 0.000 description 3
- 230000017854 proteolysis Effects 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 230000009471 action Effects 0.000 description 2
- 150000001449 anionic compounds Chemical class 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 235000014633 carbohydrates Nutrition 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 239000000460 chlorine Substances 0.000 description 2
- 239000011651 chromium Substances 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 229910001412 inorganic anion Inorganic materials 0.000 description 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical group N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- 239000011777 magnesium Substances 0.000 description 2
- 239000011572 manganese Substances 0.000 description 2
- 210000004379 membrane Anatomy 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 230000002503 metabolic effect Effects 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 230000001766 physiological effect Effects 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 239000011669 selenium Substances 0.000 description 2
- 210000000813 small intestine Anatomy 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- JBQYATWDVHIOAR-UHFFFAOYSA-N tellanylidenegermanium Chemical compound [Te]=[Ge] JBQYATWDVHIOAR-UHFFFAOYSA-N 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- 208000019901 Anxiety disease Diseases 0.000 description 1
- 102000015081 Blood Coagulation Factors Human genes 0.000 description 1
- 108010039209 Blood Coagulation Factors Proteins 0.000 description 1
- 102000016938 Catalase Human genes 0.000 description 1
- 108010053835 Catalase Proteins 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 206010011703 Cyanosis Diseases 0.000 description 1
- 230000006820 DNA synthesis Effects 0.000 description 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 description 1
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 1
- 108010073771 Soybean Proteins Proteins 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 description 1
- 206010048259 Zinc deficiency Diseases 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000036506 anxiety Effects 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000003906 autonomic nervous system functioning Effects 0.000 description 1
- 235000008452 baby food Nutrition 0.000 description 1
- 230000027455 binding Effects 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 239000003114 blood coagulation factor Substances 0.000 description 1
- 229940019700 blood coagulation factors Drugs 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 235000008429 bread Nutrition 0.000 description 1
- MKJXYGKVIBWPFZ-UHFFFAOYSA-L calcium lactate Chemical compound [Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O MKJXYGKVIBWPFZ-UHFFFAOYSA-L 0.000 description 1
- 229960002401 calcium lactate Drugs 0.000 description 1
- 239000001527 calcium lactate Substances 0.000 description 1
- 235000011086 calcium lactate Nutrition 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 230000009920 chelation Effects 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 239000010941 cobalt Substances 0.000 description 1
- 229910017052 cobalt Inorganic materials 0.000 description 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 description 1
- 239000005515 coenzyme Substances 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 230000000536 complexating effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 235000008242 dietary patterns Nutrition 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 210000001198 duodenum Anatomy 0.000 description 1
- 230000037149 energy metabolism Effects 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 238000004299 exfoliation Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 235000014106 fortified food Nutrition 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 230000004217 heart function Effects 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 150000002484 inorganic compounds Chemical class 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000004347 intestinal mucosa Anatomy 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 229910052748 manganese Inorganic materials 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000001465 metallisation Methods 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000009149 molecular binding Effects 0.000 description 1
- 229910052750 molybdenum Inorganic materials 0.000 description 1
- 239000011733 molybdenum Substances 0.000 description 1
- 230000008450 motivation Effects 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 230000037081 physical activity Effects 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229910052711 selenium Inorganic materials 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 229940001941 soy protein Drugs 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000009469 supplementation Effects 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/06—Enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/15—Inorganic Compounds
- A23V2250/156—Mineral combination
- A23V2250/1578—Calcium
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/15—Inorganic Compounds
- A23V2250/156—Mineral combination
- A23V2250/1588—Copper
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/15—Inorganic Compounds
- A23V2250/156—Mineral combination
- A23V2250/1592—Iron
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2250/00—Food ingredients
- A23V2250/15—Inorganic Compounds
- A23V2250/156—Mineral combination
- A23V2250/1642—Zinc
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Inorganic Chemistry (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Description
본 발명은 칼슘 흡수가 개선된 고효율 식품의 제조방법에 관한 것이다. 보다 상세하게는, 본 발명은 젖산의 첨가에 의하여 단백질로부터 올리고펩티드 생성을 최대화하여 칼슘 흡수를 개선시킨 고효율 식품의 제조방법에 관한 것이다.The present invention relates to a method for producing a highly efficient food with improved calcium absorption. More specifically, the present invention relates to a method for producing high-efficiency foods by maximizing oligopeptide production from proteins by addition of lactic acid to improve calcium absorption.
탄수화물, 지방 및 단백질은 기본 식단에 의해 누구나 해결하고 있으나 무기질에 대해서는 결핍하기 쉬운 식생활을 하고 있는 것이 사실이다.Carbohydrates, fats and proteins are solved by the basic diet, but it is true that the diet is easy to lack minerals.
무기질은 탄수화물, 지방, 단백질의 대사를 활성화시켜 생체의 생리활성과 성장을 촉진시키므로 모든 영양소들에게 활성을 불어 넣어 주는 원동력이 된다. 인체가 필요로 하는 무기질은 칼슘(Ca), 인(P), 나트륨(Na), 칼륨(K), 염소(Cl), 마그네슘(Mg), 황(S) 등으로서 비교적 많은 양, 즉 하루에 100 mg 이상을 섭취하여야 하고, 철(Fe), 코발트(Co), 아연(Zn), 망간(Mn), 요오드(I), 몰리브덴(Mo), 세레늄(Se), 불소(F), 크롬(Cr) 등은 아주 소량을 요한다. 비록 극미량이지만 무기질은 에너지, 성장, 체조직의 유지에 도움을 주고 신체 활동을 조절해 주는 등 중요한 역할을 하며 무기질의 부족은 신체 조직과 대사 진행에 계속적인 문제를 야기시킨다.Minerals activate the metabolism of carbohydrates, fats, and proteins to promote physiological activity and growth of living organisms, which in turn stimulates all nutrients. The minerals needed by the human body are calcium (Ca), phosphorus (P), sodium (Na), potassium (K), chlorine (Cl), magnesium (Mg), sulfur (S), etc. Intake of more than 100 mg, iron (Fe), cobalt (Co), zinc (Zn), manganese (Mn), iodine (I), molybdenum (Mo), selenium (Se), fluorine (F), chromium ( Cr) and so on require very small amounts. Although extremely small, minerals play an important role in helping to maintain energy, growth, body tissues, and regulate physical activity. Lack of minerals continues to cause problems with body tissues and metabolic progression.
한편, 무기질이 인체의 생명요소로서 완전한 기능을 발휘하기 위해서는 자연 섭생을 통해서 음식을 섭취하는 것도 중요하지만 무기질의 균형있는 흡수방법이 절실히 요구된다. 모든 식품이 소화관을 통과할 때 아무리 강력한 소화를 일으킨다 하더라도 소화물이 소화관막을 통하여 체내로 흡수되지 않으면 영양분이라 할 수 없기 때문이다.On the other hand, in order for minerals to fully function as life elements of the human body, it is also important to eat food through natural regimens, but a balanced absorption method of minerals is urgently required. No matter how strong digestion is when all foods pass through the digestive tract, it is not nutrients unless the digestion is absorbed into the body through the digestive tract membrane.
따라서, 식품에 함유된 성분의 양적 판단이 아니라 인체의 소화 흡수 조건을 바탕으로 흡수를 위주로 한 식품의 개념이 확립되어야 한다.Therefore, the concept of food based on absorption should be established based on the digestive absorption conditions of the human body rather than the quantitative determination of the ingredients contained in the food.
본 발명은 상기 문제점을 해결하기 위해 안출된 것으로서, 본 발명자들은 6대 영양소로 분류되고 있는 것 가운데 근본 물질로 작용하는 것이 무기질이라는 새로운 개념에서 흡수 기능을 고려한 인체 내 활성화에 비중을 두고 고효율 무기질 식품을 제조하여 본 발명을 완성하기에 이르렀다.The present invention has been made to solve the above problems, the inventors of the present invention are classified into six major nutrients in the new concept that acting as a fundamental substance is a mineral in the new concept of absorption in the human body considering the absorption function of high efficiency mineral food It was prepared to complete the present invention.
따라서, 본 발명은 무기질, 특히 칼슘의 흡수를 최대화시킬 수 있는 고효율 식품의 제조방법을 제공함을 그 목적으로 한다.Accordingly, an object of the present invention is to provide a method for producing a high-efficiency food that can maximize the absorption of minerals, especially calcium.
도 1은 젖산 칼슘의 이온화 작용에 의한 생화학 반응을 보인다.Figure 1 shows the biochemical reaction by the ionization action of calcium lactate.
상기 목적을 달성하기 위하여, 본 발명은 a) 단백질에 단백 분해 효소 및 젖산을 첨가하여 분해시키는 단계; 및 b) 상기 단백질 분해물에 칼슘을 배합하는 단계를 포함하는 고효율 식품의 제조방법을 제공한다.In order to achieve the above object, the present invention comprises the steps of: a) adding a proteolytic enzyme and lactic acid to the protein to degrade; And b) provides a method for producing a high-efficiency food comprising the step of combining calcium with the protein degradation product.
본 발명의 고효율 식품의 제조방법은 칼슘 이외에 철, 아연, 구리 및 이들의 혼합물로 구성되는 군으로부터 선택되는 무기질을 더욱 배합할 수 있다. 또한, 칡 분말을 더욱 배합할 수 있다.The method for producing a high-efficiency food product of the present invention may further mix minerals selected from the group consisting of iron, zinc, copper, and mixtures thereof in addition to calcium. In addition, the powder can be further blended.
바람직하게, 본 발명의 제조방법은 단백질 100 중량부에 대하여 40 내지 70 중량부의 젖산 및 13 내지 20 중량부의 칼슘을 배합한다.Preferably, the preparation method of the present invention mixes 40 to 70 parts by weight of lactic acid and 13 to 20 parts by weight of calcium based on 100 parts by weight of protein.
이하, 본 발명을 상세히 설명한다.Hereinafter, the present invention will be described in detail.
단계 a)는 단백질을 분해시키는 단계이다. 이 단계에서는 단백질 분해를 위해 단백 분해 효소와 함께 젖산을 첨가함을 특징으로 한다. 이와 같은 단백질 분해에 따라 올리고펩티드가 생성된다.Step a) is to degrade the protein. This step is characterized by the addition of lactic acid with proteolytic enzymes for proteolysis. Such proteolysis produces oligopeptides.
무기질이 소장막을 통과하려면 이온의 상태로 존재해야 흡수될 수 있다는 것이 일반적인 학설이다. 그러나, 소장 내는 약 알칼리성이므로 필수 무기질이 이온 상태로 존재한다는 것은 불가능한 일이다. 따라서 무기질은 특수한 구조물에 의존하지 않고서는 점막에서 이온의 상태를 유지할 수 없다. 즉, 위장에서 생성된 수용성 미네랄 이온은 특수한 구조를 가진 화합물의 보호를 받지 않으면 십이지장을 통과하는 소화관을 통과하는 동안 이온성을 상실하게 되어 비흡수성 무기질이 된다. 따라서, 위장으로부터 필수 무기질 이온을 보호하며 무기질 흡수처인 소장에 도달하려면 내강의 여러 가지 장해 요인을 피할 수 있는 보호막이 필요하다. 이러한 역할을 하는 것이 단백질의 부분 분해 물질인 올리고 펩티드로서 이는 필수 무기질 이온을 킬레이트화하여 이온의 상실 없이 수용성을 유지하면서 목적지까지 운송시킬 수 있다.It is a general theory that minerals must be present in the state of ions to pass through the small intestinal membrane to be absorbed. However, since the small intestine is weakly alkaline, it is impossible for essential minerals to exist in an ionic state. Thus, minerals cannot maintain the state of ions in the mucosa without relying on special structures. In other words, the water-soluble mineral ions produced in the gastrointestinal tract lose their ionicity as they pass through the digestive tract through the duodenum and become nonabsorbable minerals unless protected by a compound having a special structure. Therefore, to protect the essential mineral ions from the stomach and reach the small intestine, the mineral absorption source, a protective film is required to avoid various obstacles of the lumen. It is this oligopeptide that is a partially degradable substance of the protein, which chelates the essential mineral ions so that they can be transported to their destination while maintaining water solubility without loss of ions.
즉, 무기질이 체내에 흡수되려면 먼저 무기질이 수용성 이온의 상태로 되어야 하고, 둘째 이온화된 무기질 이온은 다른 무기 이온과 재결합하여 비수용성 무기염으로 되지 않아야 하며, 셋째 무기질 이온의 기능을 발휘할 수 있도록 장해물질의 간섭을 피할 수 있는 경계막 같은 포위체로 킬레이트화되어 분자의 중심부에 위치하여야 한다.In other words, minerals must be in the state of water-soluble ions before they can be absorbed into the body, and secondly, ionized inorganic ions must not recombine with other inorganic ions to become non-aqueous inorganic salts. It should be chelated into a membrane-like envelope that can avoid material interference and be located in the center of the molecule.
킬레이트 배위자는 수용성이고 세포막에 개입되어 흡수작용을 하는 융합 단백질과 용이한 물질이어야 하며 배위자 자신은 화학적 작용 능력이 거의 없어야 무기질 이온의 특성을 발휘할 수 있게 된다.The chelate ligand should be a soluble protein and an easy substance that is water-soluble and intercalates and absorbs the cell membrane.
무기질은 생체 내에서 소화 작용에 의하여 분해되거나 이성화되지 않는 금속성 원소로서, 무기질이 양이온으로 되려면 무기성 음이온의 도움이 필요하며 이온으로 전환된 무기질 이온은 생성됨과 동시에 배위자에 의하여 킬레이트되어 이온의 자질이 상실되지 않도로 보호되어야 한다. 무기질 이온을 배위한 분자는 무기질 이온과 올리고펩티드 사이에 배위 공유 결합을 하고 있는 상태이며 배위자 자신의 특성을 상실한 채 배위된 무기질 기능만을 발휘할 수 있도록 보존적인 활동을 하여준다. 이와 같은 체내 흡수를 위한 무기질의 배위자로서 단백질이 부분 분해된 올리고 펩티드가 이상적이다. 올리고펩티드는 아미노산이 9개 이하의 분자 결합 상태를 의미하며, 올리고펩티드 중에서 4 내지 8개의 펩티드가 바람직하다.Minerals are metallic elements that are not decomposed or isomerized by digestion in vivo. In order for the minerals to become cations, the inorganic anions need the help of inorganic anions. It must be protected against loss. Molecules for inorganic ions are in a coordinating covalent bond between the inorganic ions and the oligopeptides, and conservative activities to exert only the coordinated mineral function without losing the ligand's own properties. As an inorganic ligand for such absorption in the body, oligopeptides in which proteins are partially degraded are ideal. Oligopeptide means a state of molecular binding of 9 or less amino acids, with 4-8 peptides being preferred among oligopeptides.
한편, 일반적으로 음식을 섭취하여 분해되는 과정에서는 비수용성 폴리펩티드가 많이 생성된다. 따라서, 본 발명에서는 폴리펩티드의 생성을 억제시키고 올리고펩티드를 많이 생성시키기 위해서 분해 촉진 이온을 함유한 젖산을 배합하여 인위적으로 공급해 줌으로써 킬레이트화를 용이하게 한 것이다.On the other hand, in general, a large amount of water-insoluble polypeptides are produced during food degradation. Therefore, in the present invention, in order to inhibit the production of polypeptides and to generate a large number of oligopeptides, chelating is facilitated by mixing and artificially supplying lactic acid containing decomposition promoting ions.
한편, 효소는 생체 내에서 반응을 촉매하며 킬레이트 반응을 일으킬 수 있는 특수한 단백질 구조물로서 비타민과 무기질과 같은 전구체라 부르는 비단백 물질과도 결합될 수 있는 능력을 가지고 있다.On the other hand, the enzyme is a special protein structure that catalyzes the reaction in vivo and can cause a chelating reaction, and has the ability to bind to non-protein substances called precursors such as vitamins and minerals.
무기질 전구체와 결합하여 된 효소를 금속화 효소라고 하며 전구체는 효소로부터 쉽게 떨어져 나가는 경우가 있다. 전구체를 동반하지 못한 효소는 활성을 상실하게 된다. 즉, 단백질인 효소에 무기질 이온이 킬레이트되면 효소는 활성을 갖게 되고 반대로 무기질 이온이 효소로부터 떨어져 나가면 효소의 모든 촉매 기능은 상실하게 된다.Enzymes formed by binding to inorganic precursors are called metallization enzymes, and the precursors are easily separated from the enzymes in some cases. Enzymes that do not accompany the precursors lose their activity. In other words, if mineral ions chelate to an enzyme, which is a protein, the enzyme becomes active. On the contrary, if mineral ions are separated from the enzyme, all catalytic functions of the enzyme are lost.
무기질은 모든 대사 효소에 필수 성분으로 작용하는 등 생화학적으로 중요한 역할을 한다. 이와 같이 효소 기질에 킬레이트화되거나 착화되어 효소의 활성을 야기시키는 무기질이 결핍되면 세포 내에서 효소적 평형을 연속적으로 변화시키는 경우가 발생하게 되므로 바람직한 생리 기능 활성이 지속되지 못하고 결국 정상적인 대사 마저 진행되지 못하는 경우가 발생된다. 따라서, 무기질과 효소의 작용이 잘 이루어지도록 하기 위해서는, 무기질을 올리고펩티드에 킬레이트시켜 그 흡수가 완만하게 되도록 하는 것이 중요하다.Minerals play an important biochemical role, including essential components of all metabolic enzymes. As such, the lack of minerals chelating or complexing enzyme substrates to cause enzyme activity can result in continuous changes in enzymatic equilibrium in the cell, so that the desired physiological activity cannot be sustained and normal metabolism can not proceed. Failure occurs. Therefore, in order for the action of minerals and enzymes to work well, it is important to chelate the minerals to oligopeptides so that their absorption is slow.
효소 단백질의 화학반응을 촉진시키려면 첫째 온도를 증가시킴으로써 열에 의한 분자운동 에너지를 증가시켜 전이상태로 들어가는 분자수를 증가시켜 화학반응을 촉진시키는 경우가 있고, 둘째 반응에 촉매제를 사용하는 경우로서 촉매제는반응물질과 일시적으로 결합하여 촉매제가 없이 일어날 때 보다 더욱 낮은 활성화 에너지로 전이상태를 형성하게 하여 화학반응을 촉진시킨다. 본 발명은 후자의 방법을 택하여 촉매제로서 젖산을 사용함으로써 단백질 분해 효소의 화학 반응을 촉진시키는 것이다.In order to promote the chemical reaction of the enzyme protein, first, increase the temperature of the molecular kinetic energy by increasing the temperature to increase the number of molecules entering the transition state to promote the chemical reaction. Second, when the catalyst is used in the reaction as a catalyst It temporarily binds to the reactants to promote a chemical reaction by forming a transition state with lower activation energy than would occur without a catalyst. The present invention uses the latter method to promote the chemical reaction of proteolytic enzymes by using lactic acid as a catalyst.
단계 b)는 단계 a)에서 생성된 올리고펩티드에 칼슘을 첨가하여 킬레이트화시키는 단계이다. 상기 단계 a)에서 젖산의 첨가에 의하여 올리고펩티드 생성을 증가시킴으로써, 단계 b)에서 킬레이트되는 칼슘의 양 또한 증가시키며, 따라서 흡수되는 칼슘의 양을 증가시킬 수 있는 것이다.Step b) is the step of chelation by adding calcium to the oligopeptide produced in step a). By increasing oligopeptide production by the addition of lactic acid in step a), the amount of calcium chelated in step b) is also increased, thus increasing the amount of calcium absorbed.
이 단계에서는 보조 효소로서 칡 분말을 더욱 배합할 수 있다. 이는 미량요소의 보완 및 올리고당 보충에 충당하기 위한 것이다.At this stage, the coarse powder may be further blended as a coenzyme. This is to supplement the trace elements and oligosaccharide supplementation.
또한, 이 단계에서 칼슘 이외에 아연, 철, 구리 등의 무기질을 더욱 배합할 수 있다. 즉, 본 발명은 현대인의 식사 패턴으로 인하여 결핍되기 쉬운 칼슘(Ca), 아연(Zn), 철(Fe) 및 구리(Cu) 등의 무기질의 흡수에 역점을 둔 것이다.In addition, at this stage, minerals such as zinc, iron, and copper may be further blended in addition to calcium. That is, the present invention focuses on the absorption of minerals such as calcium (Ca), zinc (Zn), iron (Fe) and copper (Cu), which are easily deficient due to the eating pattern of modern people.
이 단계에서 첨가되는 무기질의 특성 및 중요성에 대하여 이하 설명한다.The characteristics and importance of the mineral added at this stage will be described below.
칼슘은 자율 신경계 기능의 원활화, 심장 기능 인자, 혈액 응고 인자 및 골격과 그 유사 조직에서의 구조적 기초로서 기능한다. 따라서 칼슘의 결핍은 불완전한 성장을 초래하고 생체의 기본 리듬을 상실하게 만든다. 칼슘은 무기 화합물이나 단순한 이온 상태로 흡수될 수 없으며 단백질의 부분 분해물질인 올리고펩티드와 킬레이트화 되어야 흡수되고 목적지까지 운반될 수 있다.Calcium functions as a facilitation of autonomic nervous system function, cardiac function factor, blood coagulation factor and structural basis in the skeleton and similar tissues. Thus, the lack of calcium leads to incomplete growth and loss of the body's basic rhythm. Calcium cannot be absorbed as an inorganic compound or simple ionic state, but must be chelated with oligopeptide, a partial breakdown of protein, so that it can be absorbed and transported to its destination.
아연은 DNA 합성에 없어서는 안될 무기질이며, 아연 결핍은 DNA 중합 감소를초래하며 인슐린의 기능을 저하시켜 당뇨병을 유발하는 주요 원인이 되기도 하며 장 점막에 지방이 축적되므로 다른 무기질 흡수를 지연시키는 원인이 되기도 한다.Zinc is an indispensable mineral for DNA synthesis, and zinc deficiency can lead to decreased DNA polymerization, a major cause of diabetes by lowering insulin function, and a delay in the absorption of other minerals as fat accumulates in the intestinal mucosa. do.
철은 인체가 생명을 유지하는데 필요한 산소 공급 담체로서 유일한 무기질이다. 철은 금속철, 2가철, 3가철의 형태로 즉 이온 상태를 가지기는 하지만 산화되기 쉬운 성질을 가지므로 산소와 접촉하여 비수용성 철분으로 되기 때문에 안정성이 없다.Iron is the only mineral that supplies oxygen to the human body. Iron is in the form of metal iron, divalent iron, trivalent iron, that is, it has an ionic state but is easy to be oxidized, and thus it is not stable because it becomes water-insoluble iron in contact with oxygen.
구리는 헤모글로빈의 합성, 정상적인 골격 형성 및 환원 효소인 SOD(Super Oxide Dismutas) 카탈라아제의 보결 요소로 작용하는 인자이다. 구리의 부족시 적혈구가 현저히 감소되고 정상적인 에너지 대사에 관여하는 여러 효소제에 지장을 주게 되고 뼈와 연결조직의 발육과 유지에 지장을 초래한다.Copper is a factor that acts as a complement to SOD (Super Oxide Dismutas) catalase, a synthesis of hemoglobin, normal skeletal formation, and a reducing enzyme. Lack of copper significantly reduces erythrocytes, impairs many enzymes involved in normal energy metabolism, and interferes with the development and maintenance of bone and connective tissue.
상기한 바와 같은 본 발명의 방법에 따라 제조된 식품에서는 칼슘을 포함한 다량의 무기질이 올리고펩티드에 킬레이트되어 있으므로 무기질의 체내 흡수가 증가된다.In the food prepared according to the method of the present invention as described above, since a large amount of minerals including calcium are chelated to oligopeptides, the absorption of minerals in the body is increased.
또한, 본 발명의 방법에 따라 제조된 식품을 빵, 과자, 면, 우유, 이유식 등에 첨가하여 칼슘 강화 식품을 제조할 수 있다.In addition, the food prepared according to the method of the present invention can be added to bread, confectionery, cotton, milk, baby food, etc. to produce calcium fortified food.
이하 본 발명을 하기 실시예를 참조로 하여 보다 상세히 설명한다. 그러나, 하기 실시예는 본원발명을 예시하기 위한 것일 뿐 본 발명이 이에 한정되는 것은 아니다.Hereinafter, the present invention will be described in more detail with reference to the following examples. However, the following examples are only for illustrating the present invention, and the present invention is not limited thereto.
[실시예]EXAMPLE
콩 단백질 100 g을 물에 현탁 용해시키고 프로테아제 및 젖산 63 g을 첨가하여 pH 3.5 내지 6의 상태로 유지하였다. 상기 혼합물에 칼슘 17 g, 칡 분말 5 g 및 미량의 아연, 철, 구리를 첨가한 다음 여과 농축한 후 건조시키고 분말화하여 식품을 제조하였다.100 g of soy protein was suspended in water and kept at a pH of 3.5 to 6 by addition of protease and 63 g of lactic acid. To the mixture was added 17 g of calcium, 5 g of powder, and a small amount of zinc, iron, and copper, followed by filtration, concentration, drying, and powdering to prepare a food.
상기 식품을 연령제한 없고 병약자와 건강한 자 구별 없이 30 명을 대상으로 2개월간 꿀 및 물과 함께 섭취하도록 하였다.The foods were age-restricted and ingested with honey and water for two months in 30 subjects, regardless of the sick and healthy.
그 후, 특정 설문 조사를 실시하여 다음의 결과를 얻었다.Thereafter, a specific survey was conducted to obtain the following results.
피부의 각질이 없어지고 매끄러워졌다: 25명Exfoliation and smoothness of skin: 25
피로가 없어지고 의욕이 살아났다: 28명Fatigue was removed and motivation was revived: 28
정신적인 안정과 불안요소가 제거되었다: 17명Mental stability and anxiety were removed: 17
변비가 없어졌다: 21명No Constipation: 21
위장의 무력감으로 인한 춘곤증이 없어졌다: 7명Cyanosis disappeared due to stomach weakness: 7
식욕이 왕성해졌다: 26명Appetite flourished: 26
양기가 회복되었다: 20명Yang Yi recovered: 20
관절에 통증이 없어지고 붓기가 없어졌다: 5명Painlessness and swelling in the joints: 5
이상에서 살펴 본 바와 같이, 본 발명은 젖산과 효소의 배합에 의해 무기질의 흡수를 최대화, 특히 칼슘의 흡수를 최대화시키는 효과가 있다.As described above, the present invention has the effect of maximizing the absorption of minerals, in particular the absorption of calcium by the combination of lactic acid and enzyme.
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