KR20010043630A - 치매의 치료를 위한 글루코코티코이드 수용체 길항제 - Google Patents
치매의 치료를 위한 글루코코티코이드 수용체 길항제 Download PDFInfo
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- KR20010043630A KR20010043630A KR1020007012796A KR20007012796A KR20010043630A KR 20010043630 A KR20010043630 A KR 20010043630A KR 1020007012796 A KR1020007012796 A KR 1020007012796A KR 20007012796 A KR20007012796 A KR 20007012796A KR 20010043630 A KR20010043630 A KR 20010043630A
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- dementia
- glucocorticoid receptor
- receptor antagonist
- disease
- alzheimer
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- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8570398P | 1998-05-15 | 1998-05-15 | |
| US60/085,703 | 1998-05-15 | ||
| PCT/US1998/020908 WO1999059596A1 (en) | 1998-05-15 | 1998-10-05 | Glucocorticoid receptor antagonists for the treatment of dementia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20010043630A true KR20010043630A (ko) | 2001-05-25 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020007012796A Withdrawn KR20010043630A (ko) | 1998-05-15 | 1998-10-05 | 치매의 치료를 위한 글루코코티코이드 수용체 길항제 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6369046B1 (enExample) |
| EP (1) | EP1076562B1 (enExample) |
| JP (3) | JP2003505336A (enExample) |
| KR (1) | KR20010043630A (enExample) |
| CN (1) | CN1130200C (enExample) |
| AT (1) | ATE317699T1 (enExample) |
| AU (1) | AU756818B2 (enExample) |
| CA (1) | CA2328411C (enExample) |
| DE (1) | DE69833502T2 (enExample) |
| IL (1) | IL139672A (enExample) |
| NZ (1) | NZ507449A (enExample) |
| WO (1) | WO1999059596A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6620802B1 (en) * | 1999-11-23 | 2003-09-16 | Corcept Therapeutics, Inc. | Methods of treating mild cognitive impairment using a glucocorticoid-specific receptor antagonist |
| WO2001039664A1 (en) * | 1999-12-02 | 2001-06-07 | The General Hospital Corporation | Method and apparatus for measuring indices of brain activity |
| US20010046470A1 (en) * | 2000-05-10 | 2001-11-29 | Kieko Morita | Diagnoses and treatment of disorders using an alternative glucose pathway |
| US7163934B2 (en) | 2001-05-04 | 2007-01-16 | Corcept Therapeutics, Inc. | Methods for treating delirium glucocorticoid receptor-specific antagonists |
| EP1390037B1 (en) * | 2001-05-04 | 2010-12-22 | Corcept Therapeutics, Inc. | Use of glucocorticoid receptor-specific antagonists for the treatment of delirium |
| WO2003009853A1 (en) | 2001-07-23 | 2003-02-06 | Corcept Therapeutics, Inc. | Methods for preventing antipsychotic-induced weight gain |
| NZ531477A (en) * | 2001-08-31 | 2006-10-27 | Corcept Therapeutics Inc | Use of a glucocorticoid receptor antagonist comprising a steroidal skeleton with at least one phenyl-containing moiety in the 11-beta position of the steroidal skeleton to decrease cognitive deterioration in adults with Down's syndrome |
| US7326697B2 (en) * | 2002-04-29 | 2008-02-05 | Corcept Therapeutics, Inc. | Methods for increasing the therapeutic response to electroconvulsive therapy |
| WO2004004653A2 (en) * | 2002-07-02 | 2004-01-15 | Corcept Therapeutics, Inc. | Methods for treating psychosis associated with interferon-alpha therapy |
| FR2850022B1 (fr) * | 2003-01-22 | 2006-09-08 | Centre Nat Rech Scient | Nouvelle utilisation de la mifepristone et de ses derives comme modulateurs de la voie de signalisation des proteines hedgehog et ses applications |
| US7473903B2 (en) * | 2003-02-12 | 2009-01-06 | General Electric Company | Method and apparatus for deposited hermetic cover for digital X-ray panel |
| ES2819303T3 (es) * | 2005-04-05 | 2021-04-15 | Univ Yale | Agentes moduladores del glutamato en el tratamiento de trastornos mentales |
| CA2673386A1 (en) * | 2006-12-22 | 2008-07-03 | Washington University | High performance imaging system for diffuse optical tomography and associated method of use |
| US9480425B2 (en) * | 2008-04-17 | 2016-11-01 | Washington University | Task-less optical mapping of dynamic brain function using resting state functional connectivity |
| AU2010324527A1 (en) * | 2009-11-24 | 2012-07-19 | Commonwealth Scientific And Industrial Research Organisation | Methods, kits and reagents for diagnosing, aiding diagnosis and/or monitoring progression of a neurological disorder |
| US11103514B2 (en) * | 2010-05-26 | 2021-08-31 | Corcept Therapeutics, Inc. | Treatment of muscular dystrophy |
| US10500216B2 (en) | 2011-11-18 | 2019-12-10 | Corcept Therapeutics, Inc. | Optimizing mifepristone absorption |
| WO2015187988A1 (en) * | 2014-06-04 | 2015-12-10 | Intellimedix | Composition and methods of treating epilepsy and/or epilepsy-related disorders |
| US9943526B2 (en) | 2015-04-21 | 2018-04-17 | Corcept Therapeutics, Inc. | Optimizing mifepristone levels for cushing's patients |
| US10261310B2 (en) | 2016-06-27 | 2019-04-16 | Amazon Technologies, Inc. | Amorphous silicon layer as optical filter for thin film transistor channel |
| WO2021119432A1 (en) | 2019-12-11 | 2021-06-17 | Corcept Therapeutics Incorporated | Methods of treating antipsychotic-induced weight gain with miricorilant |
| US12194036B2 (en) * | 2022-07-07 | 2025-01-14 | Antecip Bioventures Ii Llc | Combination of dextromethorphan and bupropion for treating depression |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA8231B (en) * | 1981-01-09 | 1982-11-24 | Roussel Uclaf | New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained |
| US5348729A (en) | 1988-11-30 | 1994-09-20 | The United States Of America As Represented By The Department Of Health And Human Services | Evaluative means for detecting inflammatory reactivity |
| FR2696934B1 (fr) | 1992-10-20 | 1995-06-02 | Conservatoire Nal Arts Metiers | Dérivés de stéroïdes naturels 3B hydroxyles ayant des propriétés de déclenchement et de stimulation de l'immunité, composition les contenant et procédé pour les obtenir. |
| IL110309A0 (en) * | 1993-07-15 | 1994-10-21 | Univ Kentucky Res Found | A method of protecting against neuron loss |
| IL118974A (en) | 1995-08-17 | 2001-09-13 | Akzo Nobel Nv | History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them |
| CA2250874A1 (en) | 1996-04-09 | 1997-10-16 | Btg International Limited | Use of 7 alpha-substituted steroids to treat neuropsychiatric, immune or endocrine disorders |
-
1998
- 1998-10-05 JP JP2000549261A patent/JP2003505336A/ja active Pending
- 1998-10-05 AU AU96833/98A patent/AU756818B2/en not_active Ceased
- 1998-10-05 WO PCT/US1998/020908 patent/WO1999059596A1/en not_active Ceased
- 1998-10-05 IL IL13967298A patent/IL139672A/xx not_active IP Right Cessation
- 1998-10-05 AT AT98950912T patent/ATE317699T1/de not_active IP Right Cessation
- 1998-10-05 EP EP98950912A patent/EP1076562B1/en not_active Expired - Lifetime
- 1998-10-05 CA CA002328411A patent/CA2328411C/en not_active Expired - Fee Related
- 1998-10-05 DE DE69833502T patent/DE69833502T2/de not_active Expired - Lifetime
- 1998-10-05 KR KR1020007012796A patent/KR20010043630A/ko not_active Withdrawn
- 1998-10-05 CN CN98814043A patent/CN1130200C/zh not_active Expired - Fee Related
- 1998-10-05 NZ NZ507449A patent/NZ507449A/en not_active IP Right Cessation
-
1999
- 1999-02-04 US US09/246,780 patent/US6369046B1/en not_active Expired - Lifetime
-
2008
- 2008-11-18 JP JP2008294967A patent/JP2009051864A/ja active Pending
-
2009
- 2009-05-22 JP JP2009124741A patent/JP2009185067A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009051864A (ja) | 2009-03-12 |
| ATE317699T1 (de) | 2006-03-15 |
| IL139672A0 (en) | 2002-02-10 |
| JP2003505336A (ja) | 2003-02-12 |
| NZ507449A (en) | 2003-08-29 |
| WO1999059596A1 (en) | 1999-11-25 |
| DE69833502T2 (de) | 2006-09-28 |
| EP1076562B1 (en) | 2006-02-15 |
| EP1076562A1 (en) | 2001-02-21 |
| CN1292701A (zh) | 2001-04-25 |
| CA2328411C (en) | 2008-12-16 |
| AU9683398A (en) | 1999-12-06 |
| AU756818B2 (en) | 2003-01-23 |
| CN1130200C (zh) | 2003-12-10 |
| IL139672A (en) | 2005-11-20 |
| HK1032535A1 (en) | 2001-07-27 |
| US6369046B1 (en) | 2002-04-09 |
| JP2009185067A (ja) | 2009-08-20 |
| DE69833502D1 (de) | 2006-04-20 |
| CA2328411A1 (en) | 1999-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 20001115 Patent event code: PA01051R01D Comment text: International Patent Application |
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| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |