KR20010020067A - Composition and manufacturing method of toothpaste containing aromatherapeut ic essential oils - Google Patents

Composition and manufacturing method of toothpaste containing aromatherapeut ic essential oils Download PDF

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KR20010020067A
KR20010020067A KR1019990036757A KR19990036757A KR20010020067A KR 20010020067 A KR20010020067 A KR 20010020067A KR 1019990036757 A KR1019990036757 A KR 1019990036757A KR 19990036757 A KR19990036757 A KR 19990036757A KR 20010020067 A KR20010020067 A KR 20010020067A
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toothpaste
essential oil
toothpaste composition
composition containing
composition
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KR1019990036757A
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Korean (ko)
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오세군
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오세군
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/738Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Abstract

PURPOSE: A toothpaste composition containing essential oil for aroma therapy is provided, which maintains oral hygiene and health like as existing toothpaste and also shows mental and physical balance and control by the natural essential oil which is released stably and continuously and absorbed through respiration and skin during repeated using. CONSTITUTION: A process for the preparation of toothpaste composition containing essential oil for aroma therapy is comprised of: adding cyclodextrin(CD) to free water to make a CD solution; adding essential oil mixture(e.g., Basil, Bergamot, Chamomile, Cedarwwod,Clary Sage, Eucalyptus, Lavendar, Rosemary, Mint, Geranium, Jeniper, Sinamon, Jasmin, Grape Fruits, Rose Wood, Majoram) as it is or as dissolved form in ethanol to the CD solution, shaking vigorously for 8-12 hours at room temperature, and leaving for a night; mixing the mixture with extra ingredients for toothpaste composition, such as a moisturizer, abrasive compounds, foaming agents, viscosity modifiers to prepare toothpaste by common process.

Description

아로마테라피용 에센셜 오일을 함유하는 치약 조성물 및 그의 제조방법 {Composition and manufacturing method of toothpaste containing aromatherapeut ic essential oils}Toothpaste composition containing essential oils for aromatherapy and a method of manufacturing the same {Composition and manufacturing method of toothpaste containing aromatherapeut ic essential oils}

본 발명은 습윤제, 연마제, 기포제, 착향제 등으로 구성된 종래의 치약조성물에 있어서, 향치료법(Aromatherapy)에 널리 사용되어 각종 정신 및 인체의 균형과 관리를 목적으로 사용되어온 천연의 에센셜 오일류(Essential Oils)을 특정 매개체인 싸이클로덱스트린(Cyclodextrin)로써 포접시킨 후 이것을 다시 수분산상의 종래의 치약 조성물에다 안정적으로 함유함으로써 치약 본연의 구강위생 뿐만 아니라, 치약을 반복적으로 사용하는 동안 부가적으로 치약내에 함유된 에센셜 오일에 의한 소기의 기능을 함께 주는 아로마테라피용 에센셜 오일을 함유하는 치약 조성물 및 그의 제조방법에 관한 것이다.The present invention is a conventional toothpaste composition consisting of a humectant, an abrasive, a foaming agent, a flavoring agent, and the like, which are widely used in aromatherapy and have been used for the purpose of balancing and managing various mental and human bodies. ) Is contained in the specific toothpaste (Cyclodextrin) and then stably contained in the water-dispersible conventional toothpaste composition so that not only the oral hygiene of the toothpaste, but also additionally contained in the toothpaste during repeated use of the toothpaste. The present invention relates to a toothpaste composition containing an essential oil for aromatherapy, which has a desired function by the essential oil, and a method of manufacturing the same.

종래의 치약 조성물은 습윤제, 연마제, 기포제, 점도조절제, 착향제 등으로 구성되며, 이 중에서 착향제는 사용자의 기호에 편승코자 단순 심미기능을 제공해주기 위해서 함유하는 것으로 일반적으로 식품 첨가물로서 천연의 단일향이나 다른 종류의 향과 기타 부형제를 함께 혼합한 조합향이 일정량 함유되는 것으로 알려져왔다. 또한 종래의 치약은 현재까지 구강 청결 및 위생에서부터 각종 구강질환 예방 등을 목적으로 하는 제품에 이르기까지 점점 기능화되어 가는 추세이나, 전통적 개념의 치약 기능에만 국한된 제품만으로 개발되어 보급되어 왔으며, 이에 대한 치약 조성물에 대한 기술은 미국 특허공보 제3,506,737호(살즈만) 등에 잘 기재되어 있다. 그러나, 본 발명과 같은 치약에 대한 전통적 개념의 기능이외에 향에 의한 정신 또는 인체의 균형 및 관리 기능을 부가적으로 주는 이질적 복합 개념의 기능치약에 관한 기술은 아직까지 소개된 적이 없었다.Conventional toothpaste composition is composed of a humectant, an abrasive, a foaming agent, a viscosity control agent, a flavoring agent, etc. Among these, the flavoring agent is included in order to provide a simple aesthetic function to the user's preference, and generally as a food additive, a natural single It has been known to contain a certain amount of a combination of incense or other kinds of incense and other excipients together. In addition, the conventional toothpaste has been increasingly functionalized from oral cleanliness and hygiene to products for the purpose of preventing various oral diseases, but it has been developed and distributed only with products limited to traditional toothpaste functions. Techniques for the compositions are well described in US Pat. No. 3,506,737 (Salsman) and the like. However, in addition to the function of the traditional concept of toothpaste like the present invention, the technology regarding the functional toothpaste of a heterogeneous complex concept that additionally provides the balance and management function of the mind or the human body by incense has not been introduced yet.

본 발명은 상기와 같은 종래의 치약 기능에다 향치유 기능을 부가시키는 새로운 개념의 치약으로 안출한 것으로, 치약 조성물에 있어서, 심미 효과만 주는 종래의 착향제를 대신하여 향치료법에 사용되는 천연의 에센셜 오일류를 그것들이 유분산성 유분산성(Oil-dispersible) 내지 유용성(Oil-soluble)이면서 또한 휘발성 임에도 불구하고, 일반적으로 수분산상인 종래의 치약 조성물 시스템 내에서 안정적으로 균일하게 현탁(suspension) 또는 유화(emulsification)시키면서 일정한 향치료 기능을 부여할 수 있도록 지속적으로 향을 방출시킬 수 있는 특정한 치약 조성물과 그 제조방법을 제공하려는 것인 바, 이를 본 발명의 실시예와 함께 상세히 설명하면 다음과 같다.The present invention devised as a toothpaste of a new concept that adds a healing effect to the conventional toothpaste function as described above, in the toothpaste composition, natural essential used in the perfume treatment in place of the conventional flavoring agent having only an aesthetic effect Oils may be stably and uniformly suspended or emulsified in conventional toothpaste composition systems that are generally water-dispersible, although they are oil-dispersible to oil-soluble and also volatile. It is intended to provide a specific toothpaste composition and a method for preparing the same that can continuously release the fragrance to give a certain odor treatment function while emulsification, which will be described in detail with an embodiment of the present invention.

본 발명은 치약 조성물에 있어서, 널리 사용되는 단순 심미기능을 위한 착향제 대신에 정신 및 인체의 균형과 관리를 목적으로 사용되는 천연의 에센셜 오일류를 치약내 조성물에 도입, 안정화시키되, 이를 위한 매개체로서 친수성(water- compatible)인 싸이클로덱스트린 (Cyclodextrin)을 포접시킬 게스트 화합물(Guest Compound )인 에센셜 오일의 종류에 따라 선택하여 사용하며, 그 제조 방법은 자유수에다 천연 검류를 보조 안정화제로서 포함한 수용성 치약조성 성분들을 용해시키기전에 먼저 싸이클로덱스트린을 가하여 실온에서 수용액으로 만들고 여기에 에센셜 오일을 그대로 첨가하거나 일정량의 에탄올과 같은 보조용매에 녹여 이것을 첨가하여 실온에서 몇 시간 동안 강하게 교반하고 하룻밤을 방치한 후, 여기에 연마제 등 나머지 치약조성물 성분들을 일정한 순서대로 혼합함으로써 구성된 것이다.In the toothpaste composition, natural essential oils used for the purpose of balance and management of the mind and the human body instead of the flavoring agent for simple aesthetic function widely used in the toothpaste composition, stabilized, but as a medium for It is selected and used according to the kind of essential oil, which is a guest compound to enclose a hydro-compatible cyclodextrin, and the preparation method is a water-soluble toothpaste containing free water and natural gum as an auxiliary stabilizer. Before dissolving the ingredients, add cyclodextrin to make an aqueous solution at room temperature, add essential oil to it or dissolve it in a co-solvent such as ethanol, add it, stir vigorously at room temperature for several hours, and leave overnight. The rest of the toothpaste composition such as abrasives It is composed by mixing in a certain order.

본 발명은 치약 조성물에 있어서, 아로마테라피용 에센셜 오일류를 치약내 조성물에서 안정화시키기 위한 매개체로서 친수성(water-compatible)인 싸이클로덱스트린 (Cyclodextrin)을 사용하게 되는 이유는 에센셜 오일을 종래의 치약 조성물에 그대로 투입하여 혼합시킬 경우, 많은 함량의 에센셜 오일은 그 자체가 유용성(oil-soluble)이거나 유분산성(oil-dispersible)이어서 수분산상(water- dispersible phase)인 치약 조성물과 친화가 되지 않아 시간이 경과하면서 쉽게 분리되고 또한 그것은 휘발성인고로 사용시 쉽게 휘발되거나 제품상에서 향의 지속성이 약해 만족할 만한 치약 조성물을 얻을 수 없게 되기 때문이다.In the present invention, in the toothpaste composition, the reason for using the water-compatible cyclodextrin as a medium for stabilizing the essential oils for aromatherapy in the composition in the toothpaste is that the essential oil is used as it is in the conventional toothpaste composition. When added and mixed, a large amount of essential oils are oil-soluble or oil-dispersible in themselves and are not compatible with toothpaste compositions that are water-dispersible phases. It is easily separated and also because it is volatile, and when used, it is easily volatilized or has a weak persistence of fragrance on the product, so that a satisfactory toothpaste composition cannot be obtained.

치약 조성물내에서 호스트(Host) 물질인 이 싸이클로덱스트린은 싸이클로덱스트린 (Cyclodextrin)은 분자구조에 따라 α타입, β타입, γ타입이 있는데, 이들중에서 포접시킬 게스트 화합물(Guest Compound )인 에센셜 오일의 종류에 따라 선택하여 사용함으로써 게스트 화합물인 에센셜 오일이 포접된 상태로 시간이 지나면서 에센셜 오일을 일정한 농도로 서서히 방출함으로써 에센셜 오일의 기능을 점진적으로 그리고 지속적으로 나타내도록 조절해 주는 천연의 제제이다. 싸이클로덱스트린은 이미 잘 알려진대로 전분에 바씰루스 마세란스(Bacillus Macerans)를 생성하는 전이효소(Cycloamylose Glucano Transferase)를 작용시키므로 생성되는데 이는 포도당 6∼12개가 환상 결합된 특수한 구조를 가진 환상 말트 올리고당이다.The cyclodextrin, a host substance in the dentifrice composition, has a cyclodextrin and α type, β type, and γ type depending on its molecular structure, and among them, essential oil, which is a guest compound to be included It is a natural preparation that adjusts to show gradually and continuously the function of essential oil by gradually releasing the essential oil at a constant concentration over time in a state in which the essential oil, which is a guest compound, is entrapped. Cyclodextrins, as is well known, are produced by the action of Cycloamylose Glucano Transferase, which produces Bacillus Macerans on starch.

또한 본 발명에 의한 치약에 사용되는 아로마테라피용 에센셜 오일에 대해 보다 상세한 설명을 덧붙이면 다음과 같다. 에센셜 오일에 의한 방향요법(Aromatherapy)은 고대 이집트와 중국, 인도 등지에서 식물의 잎, 뿌리, 줄기가 인간의 정신과 신체의 관리에 유익한 효과를 준다는 사실이 발견되면서부터 비롯되었다. 그리이스인들은 올리브 오일과 몰약을 이용한 화장품을 개발하여 타국에 보급하였으며, 18세기와 19세기에 이르러 첨단과학과 결합하여 피부관리, 바디관리, 기타 민간요법 등에 활용되어 왔다. 에센셜 오일은 식물의 "기" 또는 "호르몬"으로 표현되기도 하며 식물에 고단위로 축적되어 있는 생명에너지원으로 인체의 불균형을 되찾아 주며, 질병을 치유하는데 중요한 역할을 한다고 알려져 있다.In addition, a more detailed description of the essential oil for aromatherapy used in the toothpaste according to the present invention is as follows. Aromatherapy with essential oils originated from the discovery of plant leaves, roots and stems in ancient Egypt, China and India, which have beneficial effects on the management of the human mind and body. The Greeks developed cosmetics using olive oil and myrrh and spread them to other countries. By the 18th and 19th centuries, they were used in skin care, body care, and other folk remedies. Essential oils are sometimes referred to as "gi" or "hormones" of plants and are known to play an important role in relieving the imbalance of the human body and as a source of life energy accumulated in high levels in plants.

아로마테라피용 에센셜 오일이 냄새에 의해 인체에 적용되는 경로를 살펴보면 향의 흡입을 통해 대뇌의 피질 호르몬을 자극하여 인체의 균혀을 조절함으로써 비정상적으로 커진 체지방 세포의 크기를 줄여 준다는 것이다. 또한 코를 통해 흡입된 향은 뇌세포를 자극하여 신경강장, 두뇌기능 촉진, 진정효과를 준다. 이러한 에센셜 오일류 중에는 예를 들어, 바질(Basil), 버가못(Bergamot), 카모마일(Chamomile), 시다우드(Cedarwood), 클라리세이지(Clary Sage), 유카립투스(Eucalyptus), 라벤다 (Lavendar), 로즈마리(Rosemary), 민트(Mint), 제라늄 (Geranium), 제니퍼 (Jeniper), 이랑이랑(Ylang Ylang), 티토리(Titory), 시나몬(Sinamon), 쟈스민 (Jasmin), 샌달우드(Sandal Wood), 그레이프 후루츠(Grape Fruits), 로즈우드 (Rose Wood), 패츄리(Patree), 그로브(Grobe), 마죠람(Majoram), 프랑킨 센스(Frankin Cense) 등등이 있다.The aromatherapy essential oils are applied to the human body by odor, and the inhalation of incense stimulates the cortical hormones of the cerebrum and regulates the human body's coccyx to reduce the size of abnormally enlarged body fat cells. In addition, the aroma inhaled through the nose stimulates the brain cells to give nerve tonic, promote brain function, and sedative effect. Among these essential oils are, for example, Basil, Bergamot, Chamomile, Cedarwood, Clary Sage, Eucalyptus, Lavendar, Rosemary (for example). Rosemary, Mint, Geranium, Jennifer, Ylang Ylang, Titory, Cinnamon, Jasmin, Sandal Wood, Grapefruit (Grape Fruits, Rose Wood, Patree, Grove, Majoram, Frankin Cense, etc.).

본 발명에 의한 치약을 제조하는 방법을 구체적인 실시예로써 설명하면 다음과 같다.Referring to the method for producing a toothpaste according to the present invention as a specific example as follows.

1. 실시예 1 ; 치약내 자유수(Free Water) 함량이 15.0 중량% 이상인 경우1. Example 1; If the toothpaste contains more than 15.0% by weight of free water

자유수 18.6중량% 기준으로 여기에 천연 검류를 포함한 수용성 치약조성 성분들을 용해시키기전에 먼저 싸이클로덱스트린(이하 CD로 약칭한다)을 5.0중량%를 가하여 실온에서 CD 수용액을 만들고 여기에 유카립투스 및 로즈마리 등 에센셜 오일 혼합유 0.5중량%을 그대로 첨가하거나 일정량의 에탄올과 같은 보조용매에 녹여 이것을 첨가하여 실온에서 8 내지 12시간 동안 강하게 교반하고 하룻밤을 방치한 후, 여기에 연마제 등 나머지 치약조성물 성분들을 일정한 순서대로 혼합하여 치약으로 제품화하면 된다.Based on 18.6% by weight of free water, 5.0% by weight of cyclodextrin (hereinafter abbreviated as CD) is first added to dissolve the water-soluble toothpaste composition including natural gums to make an aqueous solution of CD at room temperature, and to eucalyptus and rosemary. 0.5% by weight of the essential oil mixed oil as it is, or dissolved in a co-solvent such as a certain amount of ethanol, and then it is stirred vigorously for 8 to 12 hours at room temperature and left overnight, and then the rest of the toothpaste composition such as an abrasive Mix them in order and make them into toothpaste.

2. 실시예 2 ; 치약내 자유수(Free Water) 함량이 15.0 중량% 미만인 경우2. Example 2; If free tooth content is less than 15.0 wt%

자유수 8.0중량% 기준으로 여기에 천연 검류를 포함한 수용성 치약조성 성분들을 용해시키기전에 먼저 CD를 10.0중량%를 가하여 실온 내지 섭씨 40 내지 50도씨에서 교반기나 반죽기로 강하게 교반하여 CD 수용액을 만들고 여기에 라벤다, 이랑이랑 및 카모마일 등 에센셜 오일 혼합유 1.0중량%을 그대로 첨가하거나 일정량의 에탄올과 같은 보조용매에 녹여 이것을 첨가하여 실온에서 3 내지 4시간 동안 반죽한다. 경우에 따라서는 파스타제 형상을 유지시키기 위해 공정중 약간의 물을 첨가할 수도 있다. 그런 후, 하룻밤 동안 방치하여 여기에 다시 세마제 등 나머지 치약조성물 성분들을 일정한 순서대로 혼합하여 치약으로 제품화한다.Before dissolving the water-soluble toothpaste composition including natural gums on the basis of 8.0% by weight of free water, 10.0% by weight of CD was first added, followed by vigorous stirring with a stirrer or kneader at room temperature to 40 to 50 degrees Celsius to form an aqueous CD solution. 1.0% by weight of essential oil mixed oils such as lavender, ridge and chamomile are added as they are or dissolved in a co-solvent such as a certain amount of ethanol and kneaded at room temperature for 3 to 4 hours. In some cases, some water may be added during the process to maintain the pasta shape. Then, it is allowed to stand overnight, and the rest of the toothpaste composition such as a semaphore is mixed again in a certain order to produce a toothpaste.

이러한 제법에 의해 조제된 치약 조성물의 처방예는 다음과 같다.The prescription example of the toothpaste composition prepared by such a manufacturing method is as follows.

여기서, 처방예 A는 실시예 2에 의해 조제된 경우Here, Prescription Example A is prepared by Example 2

처방예 B는 실시예 1에 의해 조제된 경우Prescription Example B is prepared by Example 1

상기와 같이 본 발명에 의한 처방예 A의 치약에 대하여 종래의 치약 처방에 의한 치약을 대조용으로 하여 20 ∼ 50 대 성인 60명을 대상으로 아래와 같이품명을 실시한 결과 <표1>과 같은 결과를 얻었다.As described above, the toothpaste of Formulation Example A according to the present invention was subjected to the following product names for 60 adults in their 20s to 50s, using the toothpaste according to the conventional toothpaste prescription as a reference. Got it.

<표 1> : 발명 치약의 사용 효과<Table 1>: Use effect of the invention toothpaste

이상과 같은 본 발명에 의한 구운 소금과 테르핀 정유을 함유하는 치약을 이용하면, 습윤제, 연마제, 기포제, 점도조절제 등으로 구성된 종래의 치약이 원래 가지고 있는 본연의 구강 위생과 건강 유지 뿐만 아니라 치약을 반복적으로 계속 사용하는 동안 본 발명의 치약 조성물내에 함유된 천연 에센셜 오일의 안정적이면서도 지속적인 방출과 그에 따른 호흡과 경피흡수를 통한 구강내 흡입에 의해서 소기의 기능을 부가적으로 제공해 주게 된다.When the toothpaste containing the roasted salt and terpine essential oil according to the present invention as described above, the toothpaste as well as the original oral hygiene and health maintenance of the conventional toothpaste composed of a humectant, an abrasive, a foaming agent, a viscosity control agent, etc. repeatedly As it continues to be used additionally provides the desired function by the stable and sustained release of the natural essential oil contained in the toothpaste composition of the present invention and the subsequent oral inhalation through respiration and percutaneous absorption.

Claims (2)

습윤제, 연마제, 점도조절제, 기포제 등으로 구성되는 치약 조성물에 있어서, 향치료법에 사용되는 천연의 에센셜 오일류를 그 종류에 따라 0.3 내지 2.5중량%만큼 α타입, β타입, γ타입의 싸이클로덱스트린의 혼합체 3.0 내지 25.0중량%에 포접시키고 이것을 다시 종래의 치약 조성물내에서 천연 검류로써 안정적으로 함유하는 것을 특징으로 하는 아로마테라피용 에센셜 오일을 함유하는 치약 조성물 및 그의 제조방법.In the toothpaste composition composed of a wetting agent, an abrasive, a viscosity control agent, a foaming agent, etc., 0.3 to 2.5% by weight of natural essential oils used in fragrance therapy according to the type of a mixture of cyclodextrins of α type, β type and γ type Toothpaste composition containing the essential oil for aromatherapy, and a method for producing the same, characterized in that it is contained in 3.0 to 25.0% by weight and stably contained as a natural gum in a conventional toothpaste composition. 제1항에 있어서, 사용되는 아로마테라피용 에센셜 오일이 바질, 버가못, 카모마일, 시다우드, 클라리 세이지, 유카립투스, 라벤다, 로즈마리, 민트, 제라늄, 제니퍼, 이랑이랑, 티토리, 시니몬, 쟈스민, 샌달우드, 그레이프 후루츠, 로즈우드, 패츄리, 그로브, 마죠람, 프랑킨 센스 중에서 선택되는 것임을 특징으로 하는 아로마테라피용 에센셜 오일을 함유하는 치약 조성물 및 그의 제조방법.The essential oils for aromatherapy used according to claim 1 are basil, bergamot, chamomile, cedarwood, clary sage, eucalyptus, lavender, rosemary, mint, geranium, jennifer, mockup, tea tree, cinimon, jasmine. Toothpaste composition containing the essential oil for aromatherapy, and a method for manufacturing the same, characterized in that selected from sandalwood, grapefruit, rosewood, patchouli, grove, marjoram, Franken sense.
KR1019990036757A 1999-08-31 1999-08-31 Composition and manufacturing method of toothpaste containing aromatherapeut ic essential oils KR20010020067A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030034273A (en) * 2001-09-07 2003-05-09 주식회사 카이아로마테라피 A composite of aroma therapy made of Lavender and Marjoram
KR20030090223A (en) * 2002-05-21 2003-11-28 주식회사 아로마휴먼텍 Duration improved essential oil composition for aromatherapy
KR20040045176A (en) * 2002-11-22 2004-06-01 김태곤 Silicone pack materials contained natural essential oils for aromatherapy
EP1566160A3 (en) * 2004-02-18 2005-10-26 GC Corporation Antimicrobial dental composition
KR100807079B1 (en) * 2002-02-19 2008-02-25 주식회사 엘지생활건강 Toothpaste Containing Plant Leaf Fragment
CN107753317A (en) * 2016-08-22 2018-03-06 上海利康消毒高科技有限公司 A kind of Chinese herbaceous peony and chamomile mixed essential oil dentistry postoperative care toothpaste

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030034273A (en) * 2001-09-07 2003-05-09 주식회사 카이아로마테라피 A composite of aroma therapy made of Lavender and Marjoram
KR100807079B1 (en) * 2002-02-19 2008-02-25 주식회사 엘지생활건강 Toothpaste Containing Plant Leaf Fragment
KR20030090223A (en) * 2002-05-21 2003-11-28 주식회사 아로마휴먼텍 Duration improved essential oil composition for aromatherapy
KR20040045176A (en) * 2002-11-22 2004-06-01 김태곤 Silicone pack materials contained natural essential oils for aromatherapy
EP1566160A3 (en) * 2004-02-18 2005-10-26 GC Corporation Antimicrobial dental composition
CN107753317A (en) * 2016-08-22 2018-03-06 上海利康消毒高科技有限公司 A kind of Chinese herbaceous peony and chamomile mixed essential oil dentistry postoperative care toothpaste

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