KR19980086246A - Extraction method of hair growth promoting ingredient from herbal medicine and extract thereof - Google Patents

Extraction method of hair growth promoting ingredient from herbal medicine and extract thereof Download PDF

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KR19980086246A
KR19980086246A KR1019970022545A KR19970022545A KR19980086246A KR 19980086246 A KR19980086246 A KR 19980086246A KR 1019970022545 A KR1019970022545 A KR 1019970022545A KR 19970022545 A KR19970022545 A KR 19970022545A KR 19980086246 A KR19980086246 A KR 19980086246A
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alopecia
ginseng
sanjoin
licorice
dermis
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KR1019970022545A
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Korean (ko)
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김인규
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김인규
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Abstract

본 발명은 당귀, 반하, 산조인, 죽여, 원지, 백복령, 용안육, 시호, 황기, 치자,감초, 맥문동, 목향, 길경, 사인, 백출, 진피, 인삼, 후박, 향부자, 빈랑, 지실, 백두구, 복신으로부터 초기 탈모증에 유효한 성분을 추출하는 방법과, 당귀, 산약, 산조인,목단피, 원지, 택사, 용안육, 백복령, 황기, 산수유, 감초, 사인, 목향, 진피, 복신, 백두구, 천궁, 건강, 백작약, 시호, 숙지황, 구기자, 인삼, 오미자, 치자로부터 중기 또는 말기 탈모증에 유효한 성분울 추출하는 방법 및 상기 방법들에 의하여 추출된 각각의 추출물에 관한 것이다.The present invention is Dongguk, half, Sanjoin, kill, Wonji, Baekbokyeong, Yongan, Siho, Astragalus, Gardenia, Licorice, Mcmundong, Mokyang, Gilgyeong, Cod, Baekchul, Dermis, Ginseng, Hubak, Hyangbuja, Betelang, Jisil, Baekdugu, Fuxin Method for extracting effective hair loss from early hair loss, Angelica, cauliflower, Sanjoin, Bark skin, raw paper, taxa, longan, Baekbokryeong, Astragalus, Cornus, Licorice, Cod, Mokji, dermis, Fuxin, Baekdu, Cheongung, Health, Earl, The present invention relates to a method for extracting ingredients effective for mid to late alopecia from Shiho, Sukjiwang, Gojija, Ginseng, Schisandra chinensis and Gardenia jasminoides and each extract extracted by the above methods.

Description

생약으로부터 발모 촉진 성분의 추출 방법 및 그 추출물Extraction method of hair growth promoting ingredient from herbal medicine and extract thereof

본 발명은 여러 가지 생약 성분으로부터 발모 촉진 작용을 갖는 성분을 추출하는 방법 및 그 추출물을 함유하는 조성물에 관한 것이다.The present invention relates to a method for extracting a component having a hair growth promoting action from various herbal ingredients and a composition containing the extract.

탈모의 기전은 아직 정확하게 밝혀져 있지 않지만, 대체적으로 호르몬 불균형등 내분비계의 이상, 자율 신경계, 혈액 순환 장애 등 순환계의 이상에 의한 과도한 피지 생성, 모근의 영양 결핍, 앨러지, 세균 감염 및 유전적 요인, 노화 등이 주원인으로 추정되어 왔으며, 최근에는 복잡한 환경에서 오는 정신적 스트레스, 대기 오염 등 환경적 요인에 대한 원인설도 대두되고 있다.The mechanism of hair loss is not yet known, but in general, excessive sebum production due to abnormalities of the endocrine system such as hormonal imbalances, autonomic nervous system, blood circulation disorders, abnormal sebum production, nutrition of hair roots, allergies, bacterial infections and genetic factors, Aging has been the main cause, and recently, the cause of environmental factors such as mental stress and air pollution from a complicated environment has been raised.

종래에는 이러한 탈모증의 치료를 위하여 여성 호르몬제, 혈행 촉진제, 비타민E, 비타민 B2조성물, 카로틴 용해제, 살균제, 모발 이식법 등이 연구되어 왔고, 약물 요법으로서는 미녹시딜이 가장 성공척인 결과를 거둔 것으로 애용되고 있으나 그 효과가 제한적이고 생체 안전성 등에 문제점이 있는 것으로 지적되고 있다.In the past, for the treatment of alopecia, hormonal agents, blood circulation promoters, vitamin E, vitamin B 2 composition, carotene dissolving agents, fungicides, hair transplantation methods, and the like have been studied. However, it is pointed out that the effect is limited and there is a problem in biosafety.

최근 탈모증 환자의 수가 증가하면서 그 발병 연령층도 크게 저하됨에 따라서 발모 촉진 및 모발 성장 효과가 확실하며 장기간 사용하여도 생체에 부작용이 없는 새로은 탈모증 치료제의 개발이 시급한 실정이다.With the recent increase in the number of alopecia patients, the age group of the onset is also greatly reduced. Therefore, it is urgent to develop a new alopecia treatment agent having no side effects on the living body, and promoting hair growth.

이에 본 발명에서는 전통적으로 민간 요법에 주로 사용되어 왔던 생체에 안전한 특정 생약들을 이상적으로 배합, 추출하여 탈모증에 효과를 갖는 성분을 추출하는 방법을 제공하고 그러한 방법에 의해 추출된 생약 추출물을 제공하고자 한다.Therefore, the present invention provides a method of extracting ingredients having an effect on alopecia by ideally combining and extracting certain biologically safe herbal medicines that have traditionally been mainly used in folk medicine, and to provide herbal extracts extracted by such methods. .

본 발명의 탈모증 치료용 조성물은 탈모의 진행 정도에 따라 초기 상태에 사용하는 제제와 중간 또는 말기 상태에 사용하는 제제를 각각 제공한다.The composition for the treatment of alopecia of the present invention provides a preparation for use in an initial state and a preparation for use in an intermediate or late stage, depending on the degree of hair loss.

본 발명에서 사용된 초기 탈모증 치료를 위한 제제에 사용하는 생약제 및 그 중량비는 다음과 같다.The herbal medicines used in the preparations for the treatment of initial alopecia and the weight ratio thereof used in the present invention are as follows.

당귀 (Angelica gigantis Radix) 60 - 100gAngelica gigantis Radix 60-100 g

반하 (Pinellae Rhizoma) 10 - 809gPinellae Rhizoma 10-809 g

산조인 (Zizyphi Spinosi Semen) 60 - 150gSanjoin (Zizyphi Spinosi Semen) 60-150 g

죽여 (Bambusae Calis in Teaniam) 60 - 100gKill (Bambusae Calis in Teaniam) 60-100g

원자 (Polygalae Radik) 60 -100gAtomic (Polygalae Radik) 60-100 g

백복령 ( Pachymae Fungus ) 60 -100gPachymae Fungus 60-100g

용안육 ( Longanae Arillus ) 60 -100gLonganae Arillus 60-100g

시호 (Bupleurum Radix) 60 -150gSeahawk (Bupleurum Radix) 60-150 g

황기 (Astragali Radix) 60 -100gAstragali Radix 60-100 g

치자 (Gardeniae Fructus) 30 -80gGardenia (Gardeniae Fructus) 30-80 g

감초 (Glycyrrhizae Radix) 60 -100gLicorice (Glycyrrhizae Radix) 60-100 g

맥문동 ( Lidopis Tuber ) 30 - 80gLidopis Tuber 30-80g

목향 (Saussureae Radix) 30 -80gMoth (Saussureae Radix) 30-80 g

질경 (Platycodi Radix) 30 -80gPlantain Radix 30-80 g

사인 (Amoni Semen) 60 -100gAmoni Semen 60-100 g

백출 (Astratylodis Rhizoma Alba) 60 -100gWhiteness (Astratylodis Rhizoma Alba) 60-100 g

진피 (Aurantii Nobilis Pericarpium) 60 -100gDermis (Aurantii Nobilis Pericarpium) 60-100 g

인삼 (Ginseng Radix) 30 - 80gGinseng (Ginseng Radix) 30-80 g

후박 (Magnoliae Cortex) 60 -100gHeavy (Magnoliae Cortex) 60-100 g

향부자 (Cyperi Rhizoma) 60 -100gHyangbuja (Cyperi Rhizoma) 60-100 g

빈랑 (Arecae Semen) 60 -100gBetel Nut (Arecae Semen) 60-100g

지실 (Ponciri Fructus) 30 -80gPonciri Fructus 30-80 g

백두구 (Amomum Cardamomum) 60 - 100gBaekdu (Amomum Cardamomum) 60-100 g

복신 60 -100gFuxin 60 -100 g

본 발명에서 사용된 중기 또는 말기 탈모증 치료를 위한, 즉 환자에게 열이없고 신장을 도와야 할 경우의 제제에 사용하는 생약제 및 그 중량비는 다음과 같다.The herbal preparations used in the present invention for the treatment of mid to late stage alopecia, that is, for the preparation of a patient without fever and need to help the kidney, and their weight ratio are as follows.

당귀 (Angelica giganits Radix) 60 -100gAngelica giganits Radix 60-100 g

산약 (Discoreae Radix) 60 - 100gPotion (Discoreae Radix) 60-100 g

산조인 (Zizyphi Spinosi Semen) 60 - 150gSanjoin (Zizyphi Spinosi Semen) 60-150 g

목단피 (Motan Radicis Cortex) 60 - 100gMotan Radicis Cortex 60-100 g

원지 (PolygaIae Radik) 60-100gOriginal paper (PolygaIae Radik) 60-100g

택사 (Alismatis Rhizoma) 60-100gTaxi (Alismatis Rhizoma) 60-100g

용안육 (Longanae Arillus) 60 -100gLonganae Arillus 60-100g

백복령 (Pachymae Fungus) 60 -100gPachymae Fungus 60-100g

황기 (Astragali Radix) 60 -100gAstragali Radix 60-100 g

산수유 (Corni Fructus) 60 -100gCornus Fructus 60-100 g

감초 (Glycyrrhizae Radix) 60 -100gLicorice (Glycyrrhizae Radix) 60-100 g

사인 (Amoni Semen) 60 -100gAmoni Semen 60-100 g

목향 (Saussureae Radix) 30 - 80gNeck Root (Saussureae Radix) 30-80 g

진피 (Aurantii Nobilis Pericarpium) 60 - 100gDermis (Aurantii Nobilis Pericarpium) 60-100 g

백두구(Amomum Cardamomum) 60 -100gBaekdugu (Amomum Cardamomum) 60-100 g

천궁 (Cnidii Rhizoma) 60 - 100gCnidii Rhizoma 60-100 g

건강 (Zingiberis Rhizoma) 60-100gHealth (Zingiberis Rhizoma) 60-100g

백작약 (Paeoniae Radix) 60 - 100gEarl (Paeoniae Radix) 60-100 g

시호 (Bupleurum Radix) 60 - 100gSeahawk (Bupleurum Radix) 60-100 g

숙지황 (Rehmanniae Radix Preparata) 30 - 80gSukjihwang (Rehmanniae Radix Preparata) 30-80g

구기자 (Lycii Fructus) 60 - 100gWolfberry (Lycii Fructus) 60-100 g

인삼 (Ginseng Radix) 30 - 80gGinseng (Ginseng Radix) 30-80 g

오미자 (Schizandrae Fructus) 60 - 100gSchizandrae Fructus 60-100 g

치자 (Gardeniae Fructus) 30 - 80gGardenia (Gardeniae Fructus) 30-80 g

복신 60 - 100gFuxin 60-100 g

상기 생약 성분을 상기의 중량비로 조합하여 탈모증 치료 작용이 있는 추출물을 제조한다. 각각의 생약 성분을 통상의 방법으로 건조시키고 미세 분말화한 후 통상의 정제수에 넣어 1 내지 2 기압으로 온도 100 내지 150℃에서 추출하여 액상으로 제조한다.Combining the herbal components in the above weight ratio to prepare an extract having a hair loss treatment action. Each herbal ingredient is dried in a conventional manner, finely powdered, and then put into ordinary purified water to extract at a temperature of 100 to 150 ° C. at 1 to 2 atmospheres to prepare a liquid phase.

상기와 같은 방법으로 추출한 본 발명의 탈모증 치료용 추출물은 약제학적으로 허용되는 보조 성분 예를 들면, 부형제, 항산화제, 보존제, 용해 보조제, 붕해제, 활탁제, 결합제, 용제 등을 가하여 정제 또는 침제, 전제. 틴크제, 엑기스제 등의 액제나, 캅셀제, 시럽제, 환제 등 내복이 가능한 형태로 제형화하여 내복함으로써 탈모증 치료에 사용할 수 있다.Extract for treating alopecia of the present invention extracted by the above method is a tablet or acupuncture by adding pharmaceutically acceptable auxiliary ingredients such as excipients, antioxidants, preservatives, dissolution aids, disintegrants, lubricants, binders, solvents, etc. , Premise. It can be used for the treatment of alopecia by formulating it in a form which can be used as an internal preparation such as a liquid such as a tin or an extract or a capsule, a syrup or a pill.

본 발명의 액제는 다음의 실시예를 통하여 추출된 추츨물을 액제로 하여 1 회100-150㎖을 1 일 1회 내지 3회 복용하며 1 개월 이상 사용하는 것이 바람직하나 이는 탈모의 정도, 나이, 체질 등에 따라 변화될 수 있다.The liquid formulation of the present invention is used as a liquid extract extracted through the following examples as a liquid 100-150ml once or three times a day and preferably used for more than one month, which is the degree of hair loss, age, It may change depending on the constitution.

이하 실시예에 의하여 본 발명을 더욱 상세히 설명한다.The present invention will be described in more detail with reference to the following examples.

실시예 1. 초기 탈모증 치료용 추출물의 제조 방법Example 1 Preparation of Extract for Treating Alopecia

당귀 60 - 100g, 반하 10 - 80g, 산조인 60 -150g, 죽여 60 - 100g, 원지 60 - 100g, 백복령 60 -100g, 용안육 60 -100g, 시호 60 -150g, 황기 60 -100g, 치자 30 - 80g, 감초 60 -100g, 맥문동 30 - 80g, 목향 30 - 80g, 길경 30 -80g, 사인 60 - 100g, 백출 60 - 100g, 진피 60 - 100g, 인삼 30 - 80g, 후박 60 - 100g, 향부자 60 -100g, 빈랑 60 - 100g, 지실 30 - 80g, 백두구 60 - 100g, 복신 60 -100g을 건조시키고 미세 분말로 한 뒤, 정제수 3000 - 5000cc를 넣고 1 내지 2기압, 100 - 150℃에서 다려 추출물을 액상 또는 환으로 제형화하여 사용한다.Angelica 60-100g, Half 10-80g, Sanjoin 60 -150g, Kill 60-100g, Base 60-100g, Baekbokyeong 60 -100g, Longan 60-100g, Seahawk 60 -150g, Astragalus 60 -100g, Gardenia 30-80g, Licorice 60-100g, Macmundong 30-80g, Mokyang 30-80g, Gilyeong 30-80g, Cod 60-100g, White roe 60-100g, Dermis 60-100g, Ginseng 30-80g, Thick 60-100g, Hyangbuja 60-100g, Betel nut 60-100g, fruit room 30-80g, Baekdugu 60-100g, fuxin 60-100g, dried into fine powder, 3000-5000cc of purified water and 1 to 2 atm, 100-150 ℃ iron extract extract liquid or Formulated for use.

실시예 2. 증기 또는 말기 탈모증 치료용 추출물의 제조 방법Example 2 Preparation of Extract for Treating Steam or Terminal Alopecia

당귀 60 -100g, 산약 60 -100g, 산조인 60 -150g, 목단피 60 -100g, 원지60 -100g, 택사 60 -100g, 용안육 60 -100g, 백복령 60 -100g, 황기 60 - 100g, 산수유 60 - 100g, 감초 60 - 100g, 사인 60 - 100g, 목향 30 - 80g, 진피 60 - 100g, 복신 60 - 100g, 백두구 60 - 100g, 천궁 60 - 100g, 건강 60 -100g, 백작약 60 -100g, 시호 60 - 100g, 숙지황 30 - 80g, 구기자 60 - 100g, 인삼 30 - 80g, 오미자 60 - 100g, 치자 30 - 80g을 건조시키고 미세 분말로 한 뒤, 정제수 3000 - 5000cc를 넣고 1 내지 2기압, 100 - 150℃에서 다려 추출물을 액상 또는 환으로 제형화하여 사용한다.Angelica 60 -100g, Acidic 60 -100g, Sanjoin 60 -150g, Peel Skin 60 -100g, Raw Paper 60 -100g, Taxa 60 -100g, Longan Meat 60 -100g, Baekbokyeong 60 -100g, Astragalus 60-100g, Cornus 60-100g, Licorice 60-100g, Cod 60-100g, Mokcho 30-80g, Dermis 60-100g, Fuxin 60-100g, Baekdu 60-100g, Cheongung 60-100g, Health 60-100g, Count 60-100g, Sea Ho 60-100g, Sulfur yellow 30-80g, wolfberry 60-100g, ginseng 30-80g, Schisandra chinensis 60-100g, Gardenia 30-80g, dried and fine powder, put purified water 3000-5000cc and ironed at 1-2 atm, 100-150 ℃ The extract is formulated in liquid or cyclic form.

탈모증은 일반적으로 장년성 탈모증(male pattern baldness), 여성 탈모증(adrogen alopecia in woman), 원형 탈모증(alopecia areata)으로 대별되고 각각의 종류에 따라 원인이 다르며 그에 따라 증상에도 다소 차이가 있으나 본 발명에 의한 생약 추출물은 장년 탈모증은 물론 여성 탈모증, 원형 탈모증에 이르기까지 완전 치유가 가능하며, 완치 후 계속적으로 수 개월 이상 연장 투여할 경우 치료는 물론 재발까지 방지하는 효과를 가져올 수 있다.Alopecia is generally classified into male pattern baldness, alopecia alopecia in woman, and alopecia areata, and the cause varies depending on the type of the alopecia, and the symptoms may vary accordingly. The herbal extracts can be fully cured from mature alopecia to female alopecia, alopecia areata, and prolonged treatment for more than a few months after cured can bring about treatment as well as relapse prevention.

본 발명의 탈모 치료용 조성물은 작용이 지속적이고 장기간 사용시 부작용이 없이 안전하게 사용할 수 있는 잇점이 있다.The composition for treating hair loss of the present invention has the advantage that the action is continuous and can be used safely without side effects when used for a long time.

실시예 3. 달모증 치료 효과Example 3. Dermatitis Treatment Effect

상기 실시예 1 또는 2의 방법에 따라 추출하여 만든 액제를 탈모 현상이 있는 환자 300명에게 30일 이상 1일 수 회 복용한 결과 300명에게 약 90%의 탈모가 중지되었고 약 70%의 발모가 확인되었다.According to the method of Example 1 or 2, the liquid extract extracted according to the method of taking 300 people with hair loss phenomenon several times a day for 30 days or more as a result of about 90% of hair loss was stopped and about 70% of hair growth Confirmed.

Claims (3)

당귀, 반하, 산조인, 죽여, 원지, 백복령, 용안육, 시호, 황기, 치자, 감초, 맥문동, 목향, 길경, 사인, 백출, 진피, 인삼, 후박, 향부자, 빈랑, 지실, 백두구, 복신을 건조시키고 미세 분말로 한 뒤, 정제수를 넣고 1 내지 2기압, 100 - 150℃에서 다려 초기 탈모증에 유효한 성분을 추출하는 방법.Danggui, half, Sanjoin, kill, Wonji, Baekbokyeong, Yongan, Shiho, Hwanggi, Gardenia, Licorice, Macmundong, Mokyang, Gilgyeong, Cod, Baekchul, Dermis, Ginseng, Hubak, Hyangbuja, Betelang, Jisil, Baekdugu, Bokshin After the fine powder is added, purified water is added at 1 to 2 atm, 100-150 ℃ iron extraction method effective for alopecia areata. 당귀, 산약, 산조인, 목단피, 원지, 택사, 용안육, 백복령, 황기, 산수유, 감초, 사인, 목향, 진피, 복신, 백두구, 천궁, 건강, 백작약, 시호, 숙지황, 구기자, 인삼, 오미자, 치자을 건조시키고 미세 분말로 한 뒤, 정제수를 넣고 1 내지 2기압, 100-150℃에서 다려 중기 또는 말기 탈모증에 유효한 성분을 추출하는 방법.Dongguk, medicinal herb, Sanjoin, silk skin, raw paper, taxi, dragon's meat, Baekbokryeong, astragalus, cornus, licorice, cod, mokyang, dermis, fuxin, baekdugu, cheongung, health, counting medicine, shiho, sujijihwang, wolfberry, ginseng, schisandra, dried gardenia After making into a fine powder, and purified water, and then extracted at 1 to 2 atm, 100-150 ° C. and extracting the ingredients effective for mid to late alopecia. 특허 청구 범위 제 1항 또는 제 2 항의 방법에 의하여 추출한 탈모 치료용 조Hair loss treatment tank extracted by the method of claim 1 or 2 성물.Relic.
KR1019970022545A 1997-05-31 1997-05-31 Extraction method of hair growth promoting ingredient from herbal medicine and extract thereof KR19980086246A (en)

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KR20010069498A (en) * 2001-03-30 2001-07-25 이태호 A method for producing a powder based on seafood and herbal medicine.
KR20020037388A (en) * 2000-11-14 2002-05-21 황인철 Depilatory and processing method thereof
KR20020095855A (en) * 2001-06-16 2002-12-28 표점덕 Silverhaired Therapy Subsidiary Pill for Medicinal Herbs of Raw Material
KR20020096780A (en) * 2001-06-18 2002-12-31 조종원 Hair loss prevention and regrowth composition and preparation method thereof
KR100382602B1 (en) * 1999-09-03 2003-05-01 송시훈 Compositions preventing lose of hair and promoting growth of hair
KR20030062994A (en) * 2002-01-22 2003-07-28 전현명 Manufacturing process of un-bitterness granulation of Sam-ryeong-baek-chul as medicinal decoction for spleen and stomach
KR20040016331A (en) * 2002-08-16 2004-02-21 (주)다모코스메틱 Hair-restorer and the manufacturing process thereof
KR20050040652A (en) * 2003-10-29 2005-05-03 박명애 Process of placenta utilzation hair restor
KR100773457B1 (en) * 2002-04-01 2007-11-05 주식회사 헬스키퍼 Composition promoting hair growth and use thereof
KR100810958B1 (en) * 2007-07-13 2008-03-10 박성웅 A composition for stopping the hair from falling out and growing hair
KR100863217B1 (en) * 2007-02-12 2008-10-13 주식회사 사임당화장품 A method for isolation and purification of calycosin and formononetin from Astragali Radix
KR100881445B1 (en) * 2002-07-19 2009-02-03 (주) 김형민한약연구소 Composition for protection of skin and improvement of skin diseases and process for preparation thereof
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KR101219239B1 (en) * 2010-02-13 2013-01-07 정길동 Hair growth solution and manufacture method thereof
KR101274257B1 (en) * 2010-02-23 2013-06-14 대구대학교 산학협력단 Composition for preventing alopecia and promoting hair growth containing essential oil from a seed of Ziziphus jujuba

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100382602B1 (en) * 1999-09-03 2003-05-01 송시훈 Compositions preventing lose of hair and promoting growth of hair
KR20020037388A (en) * 2000-11-14 2002-05-21 황인철 Depilatory and processing method thereof
KR20010069498A (en) * 2001-03-30 2001-07-25 이태호 A method for producing a powder based on seafood and herbal medicine.
KR20020095855A (en) * 2001-06-16 2002-12-28 표점덕 Silverhaired Therapy Subsidiary Pill for Medicinal Herbs of Raw Material
KR20020096780A (en) * 2001-06-18 2002-12-31 조종원 Hair loss prevention and regrowth composition and preparation method thereof
KR20030062994A (en) * 2002-01-22 2003-07-28 전현명 Manufacturing process of un-bitterness granulation of Sam-ryeong-baek-chul as medicinal decoction for spleen and stomach
KR100773457B1 (en) * 2002-04-01 2007-11-05 주식회사 헬스키퍼 Composition promoting hair growth and use thereof
KR100881445B1 (en) * 2002-07-19 2009-02-03 (주) 김형민한약연구소 Composition for protection of skin and improvement of skin diseases and process for preparation thereof
KR20040016331A (en) * 2002-08-16 2004-02-21 (주)다모코스메틱 Hair-restorer and the manufacturing process thereof
KR20050040652A (en) * 2003-10-29 2005-05-03 박명애 Process of placenta utilzation hair restor
KR100863217B1 (en) * 2007-02-12 2008-10-13 주식회사 사임당화장품 A method for isolation and purification of calycosin and formononetin from Astragali Radix
KR100810958B1 (en) * 2007-07-13 2008-03-10 박성웅 A composition for stopping the hair from falling out and growing hair
KR101033307B1 (en) * 2009-07-03 2011-05-09 김충환 Shampoo composition
KR101219239B1 (en) * 2010-02-13 2013-01-07 정길동 Hair growth solution and manufacture method thereof
KR101274257B1 (en) * 2010-02-23 2013-06-14 대구대학교 산학협력단 Composition for preventing alopecia and promoting hair growth containing essential oil from a seed of Ziziphus jujuba

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