KR102650430B1 - 다극 동기식 페동맥 무선 절제 카데터 - Google Patents
다극 동기식 페동맥 무선 절제 카데터 Download PDFInfo
- Publication number
- KR102650430B1 KR102650430B1 KR1020237009116A KR20237009116A KR102650430B1 KR 102650430 B1 KR102650430 B1 KR 102650430B1 KR 1020237009116 A KR1020237009116 A KR 1020237009116A KR 20237009116 A KR20237009116 A KR 20237009116A KR 102650430 B1 KR102650430 B1 KR 102650430B1
- Authority
- KR
- South Korea
- Prior art keywords
- electrode
- annular ring
- ablation
- pulmonary artery
- electrodes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000001147 pulmonary artery Anatomy 0.000 title claims abstract description 215
- 230000001360 synchronised effect Effects 0.000 title abstract description 14
- 230000005405 multipole Effects 0.000 title description 8
- 238000007674 radiofrequency ablation Methods 0.000 title description 2
- 238000002679 ablation Methods 0.000 claims abstract description 227
- 208000002815 pulmonary hypertension Diseases 0.000 claims abstract description 42
- 238000011282 treatment Methods 0.000 claims description 50
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 46
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 abstract description 20
- 230000002685 pulmonary effect Effects 0.000 abstract description 17
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract description 8
- 239000011780 sodium chloride Substances 0.000 abstract description 8
- 230000008901 benefit Effects 0.000 abstract description 4
- 210000004026 tunica intima Anatomy 0.000 abstract description 4
- 239000007921 spray Substances 0.000 abstract description 3
- 238000001356 surgical procedure Methods 0.000 description 67
- RFVBBELSDAVRHM-UHFFFAOYSA-N 9,10-dinaphthalen-2-yl-2-phenylanthracene Chemical compound C1=CC=CC=C1C1=CC=C(C(C=2C=C3C=CC=CC3=CC=2)=C2C(C=CC=C2)=C2C=3C=C4C=CC=CC4=CC=3)C2=C1 RFVBBELSDAVRHM-UHFFFAOYSA-N 0.000 description 62
- 230000002889 sympathetic effect Effects 0.000 description 49
- 210000005036 nerve Anatomy 0.000 description 37
- 239000003814 drug Substances 0.000 description 30
- 229940079593 drug Drugs 0.000 description 29
- 210000004126 nerve fiber Anatomy 0.000 description 23
- 238000010586 diagram Methods 0.000 description 20
- 239000007787 solid Substances 0.000 description 18
- 238000005259 measurement Methods 0.000 description 16
- 238000013500 data storage Methods 0.000 description 15
- 241001465754 Metazoa Species 0.000 description 13
- 230000000875 corresponding effect Effects 0.000 description 13
- 230000036593 pulmonary vascular resistance Effects 0.000 description 13
- 230000006872 improvement Effects 0.000 description 12
- 238000002271 resection Methods 0.000 description 12
- 206010064911 Pulmonary arterial hypertension Diseases 0.000 description 11
- 210000004204 blood vessel Anatomy 0.000 description 11
- 210000004072 lung Anatomy 0.000 description 11
- 241000282472 Canis lupus familiaris Species 0.000 description 10
- 230000004872 arterial blood pressure Effects 0.000 description 10
- 208000004248 Familial Primary Pulmonary Hypertension Diseases 0.000 description 9
- 210000001367 artery Anatomy 0.000 description 9
- 239000008280 blood Substances 0.000 description 9
- 210000004369 blood Anatomy 0.000 description 9
- 238000002592 echocardiography Methods 0.000 description 9
- 239000000463 material Substances 0.000 description 9
- 230000009467 reduction Effects 0.000 description 9
- 239000010935 stainless steel Substances 0.000 description 9
- 208000020875 Idiopathic pulmonary arterial hypertension Diseases 0.000 description 8
- 230000008859 change Effects 0.000 description 8
- 230000030214 innervation Effects 0.000 description 8
- 238000002604 ultrasonography Methods 0.000 description 8
- 101800000407 Brain natriuretic peptide 32 Proteins 0.000 description 7
- 102400000667 Brain natriuretic peptide 32 Human genes 0.000 description 7
- 101800002247 Brain natriuretic peptide 45 Proteins 0.000 description 7
- 238000002583 angiography Methods 0.000 description 7
- 210000003050 axon Anatomy 0.000 description 7
- 201000010099 disease Diseases 0.000 description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 230000000004 hemodynamic effect Effects 0.000 description 7
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 description 6
- 238000004891 communication Methods 0.000 description 6
- 230000034994 death Effects 0.000 description 6
- 231100000517 death Toxicity 0.000 description 6
- 229910001000 nickel titanium Inorganic materials 0.000 description 6
- 229960002748 norepinephrine Drugs 0.000 description 6
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 description 6
- 239000004642 Polyimide Substances 0.000 description 5
- 239000000853 adhesive Substances 0.000 description 5
- 230000001070 adhesive effect Effects 0.000 description 5
- 230000017531 blood circulation Effects 0.000 description 5
- 230000000747 cardiac effect Effects 0.000 description 5
- 238000006243 chemical reaction Methods 0.000 description 5
- 230000003205 diastolic effect Effects 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 230000002474 noradrenergic effect Effects 0.000 description 5
- URPYMXQQVHTUDU-OFGSCBOVSA-N nucleopeptide y Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(N)=O)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=C(O)C=C1 URPYMXQQVHTUDU-OFGSCBOVSA-N 0.000 description 5
- 229920001721 polyimide Polymers 0.000 description 5
- 229910001256 stainless steel alloy Inorganic materials 0.000 description 5
- 210000001519 tissue Anatomy 0.000 description 5
- 230000002792 vascular Effects 0.000 description 5
- 241000282412 Homo Species 0.000 description 4
- 238000003848 UV Light-Curing Methods 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 4
- 230000001746 atrial effect Effects 0.000 description 4
- 230000001684 chronic effect Effects 0.000 description 4
- 210000002808 connective tissue Anatomy 0.000 description 4
- 230000006378 damage Effects 0.000 description 4
- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 4
- 239000002934 diuretic Substances 0.000 description 4
- 238000004520 electroporation Methods 0.000 description 4
- 239000000835 fiber Substances 0.000 description 4
- 239000012530 fluid Substances 0.000 description 4
- 238000002073 fluorescence micrograph Methods 0.000 description 4
- 238000010438 heat treatment Methods 0.000 description 4
- 230000001976 improved effect Effects 0.000 description 4
- 238000002347 injection Methods 0.000 description 4
- 239000007924 injection Substances 0.000 description 4
- 210000000056 organ Anatomy 0.000 description 4
- 229910052760 oxygen Inorganic materials 0.000 description 4
- 239000001301 oxygen Substances 0.000 description 4
- 230000036961 partial effect Effects 0.000 description 4
- 239000002953 phosphate buffered saline Substances 0.000 description 4
- 229910001220 stainless steel Inorganic materials 0.000 description 4
- 230000000638 stimulation Effects 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 230000002861 ventricular Effects 0.000 description 4
- 229910001020 Au alloy Inorganic materials 0.000 description 3
- 241000700199 Cavia porcellus Species 0.000 description 3
- 206010008479 Chest Pain Diseases 0.000 description 3
- LTMHDMANZUZIPE-AMTYYWEZSA-N Digoxin Natural products O([C@H]1[C@H](C)O[C@H](O[C@@H]2C[C@@H]3[C@@](C)([C@@H]4[C@H]([C@]5(O)[C@](C)([C@H](O)C4)[C@H](C4=CC(=O)OC4)CC5)CC3)CC2)C[C@@H]1O)[C@H]1O[C@H](C)[C@@H](O[C@H]2O[C@@H](C)[C@H](O)[C@@H](O)C2)[C@@H](O)C1 LTMHDMANZUZIPE-AMTYYWEZSA-N 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 3
- 229910000990 Ni alloy Inorganic materials 0.000 description 3
- 208000005228 Pericardial Effusion Diseases 0.000 description 3
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 3
- 210000002565 arteriole Anatomy 0.000 description 3
- 210000000038 chest Anatomy 0.000 description 3
- 239000004020 conductor Substances 0.000 description 3
- 238000012790 confirmation Methods 0.000 description 3
- 208000018631 connective tissue disease Diseases 0.000 description 3
- 230000007423 decrease Effects 0.000 description 3
- 230000003247 decreasing effect Effects 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- LTMHDMANZUZIPE-PUGKRICDSA-N digoxin Chemical compound C1[C@H](O)[C@H](O)[C@@H](C)O[C@H]1O[C@@H]1[C@@H](C)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@@H]3C[C@@H]4[C@]([C@@H]5[C@H]([C@]6(CC[C@@H]([C@@]6(C)[C@H](O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)C[C@@H]2O)C)C[C@@H]1O LTMHDMANZUZIPE-PUGKRICDSA-N 0.000 description 3
- 229960005156 digoxin Drugs 0.000 description 3
- LTMHDMANZUZIPE-UHFFFAOYSA-N digoxine Natural products C1C(O)C(O)C(C)OC1OC1C(C)OC(OC2C(OC(OC3CC4C(C5C(C6(CCC(C6(C)C(O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)CC2O)C)CC1O LTMHDMANZUZIPE-UHFFFAOYSA-N 0.000 description 3
- 230000001882 diuretic effect Effects 0.000 description 3
- 230000005713 exacerbation Effects 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 3
- 239000010931 gold Substances 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 238000001802 infusion Methods 0.000 description 3
- 230000004007 neuromodulation Effects 0.000 description 3
- HWLDNSXPUQTBOD-UHFFFAOYSA-N platinum-iridium alloy Chemical class [Ir].[Pt] HWLDNSXPUQTBOD-UHFFFAOYSA-N 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 230000000284 resting effect Effects 0.000 description 3
- 229910001285 shape-memory alloy Inorganic materials 0.000 description 3
- 241000894007 species Species 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 239000010936 titanium Substances 0.000 description 3
- 229910052719 titanium Inorganic materials 0.000 description 3
- 210000001631 vena cava inferior Anatomy 0.000 description 3
- PJVWKTKQMONHTI-UHFFFAOYSA-N warfarin Chemical compound OC=1C2=CC=CC=C2OC(=O)C=1C(CC(=O)C)C1=CC=CC=C1 PJVWKTKQMONHTI-UHFFFAOYSA-N 0.000 description 3
- 229960005080 warfarin Drugs 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 238000003466 welding Methods 0.000 description 3
- 206010002329 Aneurysm Diseases 0.000 description 2
- 206010003658 Atrial Fibrillation Diseases 0.000 description 2
- 208000026151 Chronic thromboembolic pulmonary hypertension Diseases 0.000 description 2
- 208000002330 Congenital Heart Defects Diseases 0.000 description 2
- 108010065372 Dynorphins Proteins 0.000 description 2
- 206010013975 Dyspnoeas Diseases 0.000 description 2
- 208000005189 Embolism Diseases 0.000 description 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 description 2
- 206010018852 Haematoma Diseases 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 2
- 108020001621 Natriuretic Peptide Proteins 0.000 description 2
- 102000004571 Natriuretic peptide Human genes 0.000 description 2
- 229910000566 Platinum-iridium alloy Inorganic materials 0.000 description 2
- 239000004962 Polyamide-imide Substances 0.000 description 2
- 102100024622 Proenkephalin-B Human genes 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 description 2
- 230000000903 blocking effect Effects 0.000 description 2
- GJPICJJJRGTNOD-UHFFFAOYSA-N bosentan Chemical compound COC1=CC=CC=C1OC(C(=NC(=N1)C=2N=CC=CN=2)OCCO)=C1NS(=O)(=O)C1=CC=C(C(C)(C)C)C=C1 GJPICJJJRGTNOD-UHFFFAOYSA-N 0.000 description 2
- 229960003065 bosentan Drugs 0.000 description 2
- 238000002725 brachytherapy Methods 0.000 description 2
- 230000002490 cerebral effect Effects 0.000 description 2
- 239000013043 chemical agent Substances 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 208000028831 congenital heart disease Diseases 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 210000003191 femoral vein Anatomy 0.000 description 2
- 229910052731 fluorine Inorganic materials 0.000 description 2
- 239000011737 fluorine Substances 0.000 description 2
- 230000004217 heart function Effects 0.000 description 2
- 210000004731 jugular vein Anatomy 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000001404 mediated effect Effects 0.000 description 2
- 238000002483 medication Methods 0.000 description 2
- 239000000692 natriuretic peptide Substances 0.000 description 2
- 230000001537 neural effect Effects 0.000 description 2
- 230000001734 parasympathetic effect Effects 0.000 description 2
- 230000008506 pathogenesis Effects 0.000 description 2
- 210000004912 pericardial fluid Anatomy 0.000 description 2
- 229920002312 polyamide-imide Polymers 0.000 description 2
- 229920000728 polyester Polymers 0.000 description 2
- 239000002861 polymer material Substances 0.000 description 2
- 229920002635 polyurethane Polymers 0.000 description 2
- 239000004814 polyurethane Substances 0.000 description 2
- 210000003492 pulmonary vein Anatomy 0.000 description 2
- 230000035485 pulse pressure Effects 0.000 description 2
- BNRNXUUZRGQAQC-UHFFFAOYSA-N sildenafil Chemical compound CCCC1=NN(C)C(C(N2)=O)=C1N=C2C(C(=CC=1)OCC)=CC=1S(=O)(=O)N1CCN(C)CC1 BNRNXUUZRGQAQC-UHFFFAOYSA-N 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000035488 systolic blood pressure Effects 0.000 description 2
- 230000007704 transition Effects 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 description 1
- 239000005552 B01AC04 - Clopidogrel Substances 0.000 description 1
- 239000002126 C01EB10 - Adenosine Substances 0.000 description 1
- 229940127291 Calcium channel antagonist Drugs 0.000 description 1
- 241000282465 Canis Species 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
- 241000700198 Cavia Species 0.000 description 1
- 208000032862 Clinical Deterioration Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 241000289659 Erinaceidae Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 206010015548 Euthanasia Diseases 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 238000000729 Fisher's exact test Methods 0.000 description 1
- 238000001276 Kolmogorov–Smirnov test Methods 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 238000000585 Mann–Whitney U test Methods 0.000 description 1
- 241000282346 Meles meles Species 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 108090000189 Neuropeptides Proteins 0.000 description 1
- 102000003797 Neuropeptides Human genes 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 229930040373 Paraformaldehyde Natural products 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 229940123333 Phosphodiesterase 5 inhibitor Drugs 0.000 description 1
- 208000010378 Pulmonary Embolism Diseases 0.000 description 1
- 208000006396 Pulmonary artery stenosis Diseases 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 238000011869 Shapiro-Wilk test Methods 0.000 description 1
- 206010042434 Sudden death Diseases 0.000 description 1
- 208000001435 Thromboembolism Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 201000001943 Tricuspid Valve Insufficiency Diseases 0.000 description 1
- 206010044640 Tricuspid valve incompetence Diseases 0.000 description 1
- 208000032594 Vascular Remodeling Diseases 0.000 description 1
- HZEWFHLRYVTOIW-UHFFFAOYSA-N [Ti].[Ni] Chemical compound [Ti].[Ni] HZEWFHLRYVTOIW-UHFFFAOYSA-N 0.000 description 1
- 229960001138 acetylsalicylic acid Drugs 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 229960005305 adenosine Drugs 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 210000002376 aorta thoracic Anatomy 0.000 description 1
- 230000002567 autonomic effect Effects 0.000 description 1
- 230000003376 axonal effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229960002890 beraprost Drugs 0.000 description 1
- CTPOHARTNNSRSR-APJZLKAGSA-N beraprost Chemical compound O([C@H]1C[C@@H](O)[C@@H]([C@@H]21)/C=C/[C@@H](O)C(C)CC#CC)C1=C2C=CC=C1CCCC(O)=O CTPOHARTNNSRSR-APJZLKAGSA-N 0.000 description 1
- 239000002876 beta blocker Substances 0.000 description 1
- 229940097320 beta blocking agent Drugs 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 239000007767 bonding agent Substances 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 239000000480 calcium channel blocker Substances 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- BPHHNXJPFPEJOF-UHFFFAOYSA-J chembl296966 Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)C1=CC(S([O-])(=O)=O)=C(N)C2=C(O)C(N=NC3=CC=C(C=C3OC)C=3C=C(C(=CC=3)N=NC=3C(=C4C(N)=C(C=C(C4=CC=3)S([O-])(=O)=O)S([O-])(=O)=O)O)OC)=CC=C21 BPHHNXJPFPEJOF-UHFFFAOYSA-J 0.000 description 1
- 230000007012 clinical effect Effects 0.000 description 1
- GKTWGGQPFAXNFI-HNNXBMFYSA-N clopidogrel Chemical compound C1([C@H](N2CC=3C=CSC=3CC2)C(=O)OC)=CC=CC=C1Cl GKTWGGQPFAXNFI-HNNXBMFYSA-N 0.000 description 1
- 238000002591 computed tomography Methods 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 238000000315 cryotherapy Methods 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 230000002638 denervation Effects 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 238000002224 dissection Methods 0.000 description 1
- 229940030606 diuretics Drugs 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 238000012377 drug delivery Methods 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 238000010894 electron beam technology Methods 0.000 description 1
- 229960001123 epoprostenol Drugs 0.000 description 1
- KAQKFAOMNZTLHT-VVUHWYTRSA-N epoprostenol Chemical compound O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 125000000524 functional group Chemical group 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 239000007928 intraperitoneal injection Substances 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 238000002690 local anesthesia Methods 0.000 description 1
- 238000001325 log-rank test Methods 0.000 description 1
- 238000002595 magnetic resonance imaging Methods 0.000 description 1
- 230000005499 meniscus Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 210000001640 nerve ending Anatomy 0.000 description 1
- 230000007383 nerve stimulation Effects 0.000 description 1
- HPNRHPKXQZSDFX-OAQDCNSJSA-N nesiritide Chemical group C([C@H]1C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CSSC[C@@H](C(=O)N1)NC(=O)CNC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CO)C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1N=CNC=1)C(O)=O)=O)[C@@H](C)CC)C1=CC=CC=C1 HPNRHPKXQZSDFX-OAQDCNSJSA-N 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 238000006213 oxygenation reaction Methods 0.000 description 1
- 230000036407 pain Effects 0.000 description 1
- 238000007427 paired t-test Methods 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 229920002866 paraformaldehyde Polymers 0.000 description 1
- 210000001002 parasympathetic nervous system Anatomy 0.000 description 1
- 230000007310 pathophysiology Effects 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 229960001412 pentobarbital Drugs 0.000 description 1
- WEXRUCMBJFQVBZ-UHFFFAOYSA-N pentobarbital Chemical compound CCCC(C)C1(CC)C(=O)NC(=O)NC1=O WEXRUCMBJFQVBZ-UHFFFAOYSA-N 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000002590 phosphodiesterase V inhibitor Substances 0.000 description 1
- 229940020573 plavix Drugs 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 208000007232 portal hypertension Diseases 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 201000008312 primary pulmonary hypertension Diseases 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 238000004393 prognosis Methods 0.000 description 1
- 208000005069 pulmonary fibrosis Diseases 0.000 description 1
- 210000003102 pulmonary valve Anatomy 0.000 description 1
- 201000010298 pulmonary valve insufficiency Diseases 0.000 description 1
- 208000009138 pulmonary valve stenosis Diseases 0.000 description 1
- 208000030390 pulmonic stenosis Diseases 0.000 description 1
- 239000002464 receptor antagonist Substances 0.000 description 1
- 229940044551 receptor antagonist Drugs 0.000 description 1
- 230000011514 reflex Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 201000004193 respiratory failure Diseases 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 230000000552 rheumatic effect Effects 0.000 description 1
- 210000005245 right atrium Anatomy 0.000 description 1
- 210000005241 right ventricle Anatomy 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 208000037812 secondary pulmonary hypertension Diseases 0.000 description 1
- 230000001953 sensory effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000012781 shape memory material Substances 0.000 description 1
- 229960003310 sildenafil Drugs 0.000 description 1
- 229960002256 spironolactone Drugs 0.000 description 1
- LXMSZDCAJNLERA-ZHYRCANASA-N spironolactone Chemical compound C([C@@H]1[C@]2(C)CC[C@@H]3[C@@]4(C)CCC(=O)C=C4C[C@H]([C@@H]13)SC(=O)C)C[C@@]21CCC(=O)O1 LXMSZDCAJNLERA-ZHYRCANASA-N 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 238000011272 standard treatment Methods 0.000 description 1
- 210000004686 stellate ganglion Anatomy 0.000 description 1
- 210000001321 subclavian vein Anatomy 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 210000002820 sympathetic nervous system Anatomy 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000008719 thickening Effects 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 210000001186 vagus nerve Anatomy 0.000 description 1
- 230000002227 vasoactive effect Effects 0.000 description 1
- 229940124549 vasodilator Drugs 0.000 description 1
- 239000003071 vasodilator agent Substances 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/1206—Generators therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00029—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids open
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00345—Vascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00541—Lung or bronchi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00577—Ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00791—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/1206—Generators therefor
- A61B2018/1226—Generators therefor powered by a battery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1405—Electrodes having a specific shape
- A61B2018/1407—Loop
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1467—Probes or electrodes therefor using more than two electrodes on a single probe
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plasma & Fusion (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Otolaryngology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Surgical Instruments (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020247009010A KR102766112B1 (ko) | 2014-07-11 | 2015-07-10 | 다극 동기식 페동맥 무선 절제 카데터 |
Applications Claiming Priority (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462023781P | 2014-07-11 | 2014-07-11 | |
| US62/023,781 | 2014-07-11 | ||
| US14/666,214 | 2015-03-23 | ||
| US14/666,214 US9827036B2 (en) | 2012-11-13 | 2015-03-23 | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter |
| US14/672,010 | 2015-03-27 | ||
| US14/672,013 US9918776B2 (en) | 2012-11-13 | 2015-03-27 | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter |
| US14/672,013 | 2015-03-27 | ||
| US14/672,021 US9872720B2 (en) | 2012-11-13 | 2015-03-27 | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter |
| US14/672,010 US9820800B2 (en) | 2012-11-13 | 2015-03-27 | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter |
| US14/672,021 | 2015-03-27 | ||
| KR1020217003781A KR102513522B1 (ko) | 2014-07-11 | 2015-07-10 | 다극 동기식 페동맥 무선 절제 카데터 |
| PCT/US2015/039930 WO2016007851A1 (en) | 2014-07-11 | 2015-07-10 | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217003781A Division KR102513522B1 (ko) | 2014-07-11 | 2015-07-10 | 다극 동기식 페동맥 무선 절제 카데터 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020247009010A Division KR102766112B1 (ko) | 2014-07-11 | 2015-07-10 | 다극 동기식 페동맥 무선 절제 카데터 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20230042403A KR20230042403A (ko) | 2023-03-28 |
| KR102650430B1 true KR102650430B1 (ko) | 2024-03-25 |
Family
ID=55064957
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020247009010A Active KR102766112B1 (ko) | 2014-07-11 | 2015-07-10 | 다극 동기식 페동맥 무선 절제 카데터 |
| KR1020237009116A Active KR102650430B1 (ko) | 2014-07-11 | 2015-07-10 | 다극 동기식 페동맥 무선 절제 카데터 |
| KR1020217003781A Active KR102513522B1 (ko) | 2014-07-11 | 2015-07-10 | 다극 동기식 페동맥 무선 절제 카데터 |
| KR1020177003851A Active KR102219632B1 (ko) | 2014-07-11 | 2015-07-10 | 다극 동기식 페동맥 무선 절제 카데터 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020247009010A Active KR102766112B1 (ko) | 2014-07-11 | 2015-07-10 | 다극 동기식 페동맥 무선 절제 카데터 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217003781A Active KR102513522B1 (ko) | 2014-07-11 | 2015-07-10 | 다극 동기식 페동맥 무선 절제 카데터 |
| KR1020177003851A Active KR102219632B1 (ko) | 2014-07-11 | 2015-07-10 | 다극 동기식 페동맥 무선 절제 카데터 |
Country Status (10)
| Country | Link |
|---|---|
| EP (3) | EP4014908B1 (enExample) |
| JP (4) | JP6608924B2 (enExample) |
| KR (4) | KR102766112B1 (enExample) |
| CN (2) | CN107072707B (enExample) |
| AU (4) | AU2015287691B2 (enExample) |
| BR (1) | BR112017000610B1 (enExample) |
| CA (2) | CA2954897A1 (enExample) |
| RU (1) | RU2692219C2 (enExample) |
| SG (2) | SG11201700223PA (enExample) |
| WO (1) | WO2016007851A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8585601B2 (en) | 2010-10-18 | 2013-11-19 | CardioSonic Ltd. | Ultrasound transducer |
| AU2012347470B2 (en) | 2011-12-09 | 2017-02-02 | Medtronic Ireland Manufacturing Unlimited Company | Therapeutic neuromodulation of the hepatic system |
| WO2013134543A1 (en) | 2012-03-08 | 2013-09-12 | Medtronic Ardian Luxembourg Sarl | Immune system neuromodulation and associated systems and methods |
| US11357447B2 (en) | 2012-05-31 | 2022-06-14 | Sonivie Ltd. | Method and/or apparatus for measuring renal denervation effectiveness |
| US11241267B2 (en) | 2012-11-13 | 2022-02-08 | Pulnovo Medical (Wuxi) Co., Ltd | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter |
| CN102908191A (zh) | 2012-11-13 | 2013-02-06 | 陈绍良 | 多极同步肺动脉射频消融导管 |
| US9827036B2 (en) | 2012-11-13 | 2017-11-28 | Pulnovo Medical (Wuxi) Co., Ltd. | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter |
| US12082868B2 (en) | 2012-11-13 | 2024-09-10 | Pulnovo Medical (Wuxi) Co., Ltd. | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter |
| JP2017536187A (ja) | 2014-12-03 | 2017-12-07 | メタベンション インコーポレイテッド | 神経または他の組織を調節するためのシステムおよび方法 |
| US11350987B2 (en) | 2015-01-28 | 2022-06-07 | St. Jude Medical, Cardiology Division, Inc. | Thermal mapping catheter |
| US10524859B2 (en) | 2016-06-07 | 2020-01-07 | Metavention, Inc. | Therapeutic tissue modulation devices and methods |
| RU2694583C1 (ru) * | 2016-12-13 | 2019-07-16 | Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт комплексных проблем сердечно-сосудистых заболеваний" (НИИ КПССЗ) | Способ лечения резистивной артериальной легочной гипертензии |
| EP3600541A4 (en) | 2017-03-20 | 2020-03-18 | Sonivie Ltd. | METHOD FOR TREATING HEART FAILURE BY IMPROVING THE EJECTION FRACTION OF A PATIENT |
| US11672947B2 (en) | 2017-11-28 | 2023-06-13 | St. Jude Medical, Cardiology Division, Inc. | Lumen management catheter |
| JP7499702B2 (ja) | 2018-05-21 | 2024-06-14 | セント・ジュード・メディカル，カーディオロジー・ディヴィジョン，インコーポレイテッド | 高周波アブレーション及び直流電気穿孔カテーテル |
| EP3893755A4 (en) | 2018-12-13 | 2023-01-25 | NXT Biomedical, LLC | METHODS AND DEVICES FOR BLOOD OXYGENATION TREATMENT |
| CN110897710B (zh) * | 2019-11-30 | 2021-08-31 | 杭州堃博生物科技有限公司 | 肺部神经消融系统的控制方法、系统以及计算机介质 |
| US20220047326A1 (en) * | 2020-08-13 | 2022-02-17 | Biosense Webster (Israel) Ltd. | Applying Bipolar Ablation Energy Between Shorted Electrode Groups |
| CN115942915B (zh) | 2020-08-18 | 2025-11-28 | 圣犹达医疗用品心脏病学部门有限公司 | 具有磁性位置跟踪的高密度电极导管 |
| US12082877B2 (en) | 2021-01-22 | 2024-09-10 | CRC EP, Inc. | Ablation catheter and operation method of same |
| MX2023011506A (es) | 2021-04-07 | 2023-12-07 | Btl Medical Dev A S | Dispositivo y metodo de ablacion de campo pulsado. |
| EP4108197A1 (en) | 2021-06-24 | 2022-12-28 | Gradient Denervation Technologies | Systems for treating tissue |
| MX2023015018A (es) | 2021-07-06 | 2024-05-08 | Btl Medical Dev A S | Dispositivo y metodo de ablacion de campo pulsado. |
| CR20250188A (es) | 2022-10-05 | 2025-08-22 | Btl Medical Dev A S | Dispositivo y método de ablación de campo pulsado |
| WO2025227077A1 (en) * | 2024-04-25 | 2025-10-30 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Radiofrequency ablation device |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997033526A2 (en) | 1996-03-11 | 1997-09-18 | Medtronic, Inc. | Method and apparatus for r-f ablation |
| JP2000500363A (ja) * | 1995-11-13 | 2000-01-18 | イーピー テクノロジーズ，インコーポレイテッド | 長い損傷を形成するための可撓性組織切除要素 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0861676B1 (en) * | 1993-11-10 | 2003-10-01 | Medtronic Cardiorhythm | Electrode array catheter |
| US6575969B1 (en) * | 1995-05-04 | 2003-06-10 | Sherwood Services Ag | Cool-tip radiofrequency thermosurgery electrode system for tumor ablation |
| US20050010095A1 (en) * | 1999-04-05 | 2005-01-13 | Medtronic, Inc. | Multi-purpose catheter apparatus and method of use |
| EP2712567A1 (en) * | 1999-11-22 | 2014-04-02 | Boston Scientific Limited | Loop structures for supporting diagnostic and therapeutic elements in contact with body tissue |
| JP3895531B2 (ja) * | 2000-09-01 | 2007-03-22 | オリンパス株式会社 | 電気手術装置 |
| US6866662B2 (en) * | 2002-07-23 | 2005-03-15 | Biosense Webster, Inc. | Ablation catheter having stabilizing array |
| US20060241366A1 (en) * | 2002-10-31 | 2006-10-26 | Gary Falwell | Electrophysiology loop catheter |
| US7235070B2 (en) * | 2003-07-02 | 2007-06-26 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Ablation fluid manifold for ablation catheter |
| US8657814B2 (en) * | 2005-08-22 | 2014-02-25 | Medtronic Ablation Frontiers Llc | User interface for tissue ablation system |
| JP2009543607A (ja) * | 2006-07-10 | 2009-12-10 | ボエッジ メディカル， インコーポレイテッド | 心房細動の治療のための方法および装置 |
| JP4027411B1 (ja) * | 2007-03-29 | 2007-12-26 | 日本ライフライン株式会社 | 電極カテーテル |
| US8712550B2 (en) * | 2008-12-30 | 2014-04-29 | Biosense Webster, Inc. | Catheter with multiple electrode assemblies for use at or near tubular regions of the heart |
| US8540662B2 (en) * | 2009-03-24 | 2013-09-24 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Medical devices having an atraumatic distal tip segment |
| CA2780608C (en) * | 2009-11-11 | 2019-02-26 | Innovative Pulmonary Solutions, Inc. | Systems, apparatuses, and methods for treating tissue and controlling stenosis |
| US9907607B2 (en) * | 2009-12-30 | 2018-03-06 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Guide and flexible sleeve for use with catheters |
| US8369923B2 (en) * | 2010-04-14 | 2013-02-05 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Dual-deflecting electrophysiology catheter |
| US9943363B2 (en) | 2010-04-28 | 2018-04-17 | Biosense Webster, Inc. | Irrigated ablation catheter with improved fluid flow |
| WO2012061161A1 (en) * | 2010-10-25 | 2012-05-10 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter apparatuses having multi-electrode arrays for renal neuromodulation and associated systems and methods |
| US8792962B2 (en) * | 2010-12-30 | 2014-07-29 | Biosense Webster, Inc. | Catheter with single axial sensors |
| CN202637103U (zh) * | 2011-08-26 | 2013-01-02 | 王捷 | 具有肾神经标测功能的导管 |
| WO2013076588A2 (en) * | 2011-11-07 | 2013-05-30 | Medtronic Ardian Luxembourg S.A.R.L. | Endovascular nerve monitoring devices and associated systems and methods |
| WO2013090848A1 (en) * | 2011-12-15 | 2013-06-20 | The Board Of Trustees Of The Leland Stanford Junior University | Apparatus and methods for treating pulmonary hypertension |
| CN102908191A (zh) * | 2012-11-13 | 2013-02-06 | 陈绍良 | 多极同步肺动脉射频消融导管 |
| CN202982207U (zh) * | 2012-11-13 | 2013-06-12 | 陈绍良 | 治疗肺动脉高压的多极同步射频消融导管 |
| CN103908334A (zh) * | 2012-12-31 | 2014-07-09 | 上海微创电生理医疗科技有限公司 | 多电极消融导管 |
| US9050010B2 (en) * | 2012-12-31 | 2015-06-09 | Biosense Webster (Israel) Ltd. | Double loop lasso with single puller wire for bi-directional actuation |
-
2015
- 2015-07-10 SG SG11201700223PA patent/SG11201700223PA/en unknown
- 2015-07-10 KR KR1020247009010A patent/KR102766112B1/ko active Active
- 2015-07-10 KR KR1020237009116A patent/KR102650430B1/ko active Active
- 2015-07-10 KR KR1020217003781A patent/KR102513522B1/ko active Active
- 2015-07-10 CN CN201580049382.XA patent/CN107072707B/zh active Active
- 2015-07-10 RU RU2017101338A patent/RU2692219C2/ru active
- 2015-07-10 BR BR112017000610-3A patent/BR112017000610B1/pt active IP Right Grant
- 2015-07-10 CN CN202010799806.7A patent/CN112704559B/zh active Active
- 2015-07-10 JP JP2017522463A patent/JP6608924B2/ja active Active
- 2015-07-10 SG SG10201800251YA patent/SG10201800251YA/en unknown
- 2015-07-10 KR KR1020177003851A patent/KR102219632B1/ko active Active
- 2015-07-10 AU AU2015287691A patent/AU2015287691B2/en active Active
- 2015-07-10 EP EP22155626.9A patent/EP4014908B1/en active Active
- 2015-07-10 WO PCT/US2015/039930 patent/WO2016007851A1/en not_active Ceased
- 2015-07-10 CA CA2954897A patent/CA2954897A1/en active Pending
- 2015-07-10 EP EP25187226.3A patent/EP4647111A2/en active Pending
- 2015-07-10 CA CA3201993A patent/CA3201993A1/en active Pending
- 2015-07-10 EP EP15818364.0A patent/EP3166524B1/en active Active
-
2019
- 2019-07-04 AU AU2019204804A patent/AU2019204804B2/en active Active
- 2019-10-24 JP JP2019193400A patent/JP2020044338A/ja active Pending
-
2020
- 2020-10-07 AU AU2020250197A patent/AU2020250197B2/en active Active
-
2021
- 2021-11-29 JP JP2021192988A patent/JP7653346B2/ja active Active
-
2022
- 2022-04-26 AU AU2022202710A patent/AU2022202710B2/en active Active
-
2024
- 2024-12-02 JP JP2024209230A patent/JP2025027101A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000500363A (ja) * | 1995-11-13 | 2000-01-18 | イーピー テクノロジーズ，インコーポレイテッド | 長い損傷を形成するための可撓性組織切除要素 |
| WO1997033526A2 (en) | 1996-03-11 | 1997-09-18 | Medtronic, Inc. | Method and apparatus for r-f ablation |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR102650430B1 (ko) | 다극 동기식 페동맥 무선 절제 카데터 | |
| US12458427B2 (en) | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter | |
| US11241267B2 (en) | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter | |
| HK40051288A (zh) | 多极同步肺动脉射频消融导管 | |
| HK40051288B (en) | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter | |
| HK1234978A1 (en) | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter | |
| HK1234978B (en) | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter | |
| HK1235654A1 (en) | Multi-pole synchronous pulmonary artery radiofrequency ablation catheter |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A107 | Divisional application of patent | ||
| PA0104 | Divisional application for international application |
Comment text: Divisional Application for International Patent Patent event code: PA01041R01D Patent event date: 20230315 Application number text: 1020217003781 Filing date: 20210205 |
|
| PA0201 | Request for examination | ||
| PG1501 | Laying open of application | ||
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20230531 Patent event code: PE09021S01D |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 20231219 |
|
| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
Comment text: Registration of Establishment Patent event date: 20240319 Patent event code: PR07011E01D |
|
| PR1002 | Payment of registration fee |
Payment date: 20240320 End annual number: 3 Start annual number: 1 |
|
| PG1601 | Publication of registration |