KR102621024B1 - A hydrogel patch for improving aesthetics and skin absorption - Google Patents

Abstract

The present invention relates to a hydrogel patch that can flexibly achieve aesthetics, comprising: a synthetic resin base layer; and a hydrogel layer laminated on one side of the synthetic resin base layer, wherein the hydrogel layer includes a polyhydric alcohol, a natural polymer gelling agent, and a synthetic polymer gelling agent.

Description

Hydrogel patch with improved aesthetics and skin absorption {A HYDROGEL PATCH FOR IMPROVING AESTHETICS AND SKIN ABSORPTION}

The present invention relates to a hydrogel patch with significantly improved aesthetics and skin absorption by using a film-type support that could not be used as a support in conventional patch-type products.

Recently, attachable patch formulations have been widely used to compensate for the shortcomings of cream formulations, and a representative example is the hydrogel-based cataplasma formulation.

Hydrogel can contain a large amount of moisture and active ingredients within a three-dimensional polymer network, and can continuously supply active ingredients for a long time by inducing hydration of the stratum corneum of the skin.

However, theoretically, the strength and adhesiveness of a hydrogel patch are inversely proportional, and a technology to optimize the mixing ratio of the polymer that makes up the matrix and the adhesive polymer is essential. In order to strengthen the adhesive, the main ingredients contained in the matrix are essential. emission can be suppressed.

Meanwhile, patch products in the form of cataplasma with adhesion, such as conventional V-line patches, sports patches, body patches, and mask patches, use fabric as a support.

Figure 1 shows a patch product in the form of a cataplasma using a conventional fabric support.

However, conventional patch products have many problems due to the use of fabric as a support.

Since the fabric has the property of absorbing moisture, the side on which the fabric is laminated, rather than the side attached to the skin, comes into contact with the external air layer, causing moisture to evaporate and the active ingredients not being fully absorbed into the skin.

In addition, since the fabric support has the property of absorbing moisture, the quality of the product may deteriorate as the fabric support becomes wet, and additional water-repellent coating on the fabric may be required to improve this.

In addition, due to the nature of the patch product, if the thickness of the fabric support is thick or the weight is high, the possibility of it being easily separated from the skin surface increases. When a light fabric support is applied to improve this problem, the above-described shortcomings are further aggravated.

Additionally, since the fabric support is manufactured by twisting and weaving yarn, problems such as the edges of the fabric not being cut cleanly and seams forming occur, and since the fabric support is opaque, it is difficult to implement various design characteristics, which limits aesthetics.

However, in order to solve this problem, when a transparent film with moisture impermeability is used as a support, there is a problem that the support and the hydrogel are easily separated due to the smooth surface characteristics of the film and cannot substantially function as a support.

Accordingly, the present inventors developed a hydrogel composition that firmly binds to the support and applied it together with a film support having certain characteristics, thereby completing a new type of hydrogel patch that improved the disadvantages of conventional fabrics.

The present invention is intended to solve the problems of the prior art described above. The purpose of the present invention is to simultaneously realize the high adhesion, which is the advantage of the insoluble hydrogel patch, and the moisturizing feeling, which is the advantage of the water-soluble hydrogel patch, and to provide a light-transmitting synthetic resin support and The goal is to provide a hydrogel patch that binds firmly.

According to one aspect of the present invention, a synthetic resin base layer; and a hydrogel layer laminated on one side of the synthetic resin base layer, wherein the hydrogel layer includes a polyhydric alcohol, a natural polymer gelling agent, and a synthetic polymer gelling agent.

In one embodiment, the hydrogel layer may further include a synthetic polymer thickener.

In one embodiment, the synthetic resin base layer may be made of a light-transmissive material.

In one embodiment, the hydrogel layer may include 40 to 80 parts by weight of the natural polymer gelling agent, 30 to 60 parts by weight of the synthetic polymer gelling agent, and 100 to 400 parts by weight of the synthetic polymer thickener.

In one embodiment, the synthetic polymer thickener is polyacrylic acid or ethylene/acrylic acid copolymer, ethylene/acrylic acid/VA copolymer, ethylene/calcium acrylate copolymer, ethylene/sodium acrylate copolymer, acrylate. /VP copolymer, acrylate/VA copolymer, acrylate copolymer, hydroxyethyl cellulose, and carboxyvinyl polymer.

In one embodiment, the synthetic resin base layer includes polyethylene (PE), polystyrene (PS), polyethylene terephthalate (PET), polypropylene (PP), thermoplastic polyurethane (TPU), polycarbonate (PC), and polycaprolactone. It may be manufactured from one or more selected from the group consisting of (PCL), polyacetal (POM), polyvinyl chloride (PVC), polyvinyl alcohol (PVA), polyamide (PA), and Teflon.

In one embodiment, the hydrogel layer may further include one or more colorants.

In one embodiment, the colorant is dye; extender pigments including talc, mica, kaolin, calcium carbonate, mica, talc, kaolin, alumina, barium silicate, zeolite, muscovite, magnesium carbonate, and barium sulfate; coloring pigments including bengara, iron sulfate, black iron oxide, red iron oxide, chromium oxide, ultramarine blue, royal blue, and carbon black; White pigment containing titanium dioxide and zinc oxide; Organic pigments containing tar colorants; lake; Pearl pigments including titanium dioxide, titanium mica, iron titanate and titanium oxide coated mica, silica, tin oxide, and ferric ferrocyanide; and natural pigments including beta-carotene, cartamine, and cochineal. One or more may be selected from the group consisting of.

In one embodiment, the hydrogel layer may be composed of a first hydrogel layer and a second hydrogel layer containing distinct colorants.

According to the present invention, the hydrogel patch uses a synthetic resin support to suppress moisture evaporation, so even if it is attached for a long time, the active ingredient continues to act on the skin, and functionality such as skin moisturizing effect can be significantly improved.

Since the hydrogel patch uses a synthetic resin support made of light-transmissive material, it can provide aesthetic properties such as pearl or color to the hydrogel, thereby creating a new aesthetic that could not be achieved in conventional products.

The hydrogel patch has excellent adhesion, so it can be attached to the skin for a long time without flowing or slipping, and provides a long-term moisturizing and skin soothing effect, while providing a pulling effect to the skin due to its excellent elasticity, so it can provide a substantial lifting effect.

The effects of the present invention are not limited to the effects described above, and should be understood to include all effects that can be inferred from the configuration of the invention described in the detailed description or claims of the present invention.

Figure 1 shows a patch product in the form of a cataplasma using a conventional fabric support.
Figure 2 shows the layered structure of a hydrogel patch according to an embodiment of the present invention.
Figure 3 shows the actual implementation of a hydrogel patch according to an embodiment of the present invention.
Figure 4 shows the actual implementation of a hydrogel patch according to another embodiment of the present invention.

The terms used in this specification are general terms that are currently widely used as much as possible while considering the function in the present invention, but this may vary depending on the intention or precedent of a person skilled in the art, the emergence of new technology, etc.

In addition, in certain cases, there are terms arbitrarily selected by the applicant, and in this case, the meaning will be described in detail in the description of the relevant invention. Therefore, the terms used in the present invention should be defined based on the meaning of the term and the overall content of the present invention, rather than simply the name of the term.

Unless otherwise defined, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by a person of ordinary skill in the technical field to which the present invention pertains. Terms defined in commonly used dictionaries should be interpreted as having a meaning consistent with the meaning in the context of the related technology, and unless clearly defined in the present application, should not be interpreted in an ideal or excessively formal sense. No.

The numerical range includes the values defined in the range above. Every maximum numerical limit given throughout this specification includes all lower numerical limits as if the lower numerical limit were explicitly written out. Every minimum numerical limit given throughout this specification includes every higher numerical limit as if such higher numerical limit was clearly written. All numerical limits given throughout this specification will include all better numerical ranges within the broader numerical range, as if the narrower numerical limits were clearly written.

Hereinafter, examples of the present invention will be described in detail, but it is obvious that the present invention is not limited to the following examples.

One aspect of the present invention is a synthetic resin base layer; and a hydrogel layer laminated on one side of the synthetic resin base layer, wherein the hydrogel layer includes a polyhydric alcohol, a natural polymer gelling agent, and a synthetic polymer gelling agent.

The hydrogel patch refers to a product in which a whitening, moisturizing, and other functional hydrogel layer is laminated on a base layer in a shape corresponding to the face or application area, and can be easily attached and used without the need to apply separate cosmetics to the outer surface of the skin. .

Referring to Figure 2, the base layer includes the hydrogel layer on one side, and the base layer is located on a predetermined area of the user's skin so that the hydrogel layer laminated on one side is in contact with the skin surface.

The shape or size of the hydrogel patch is not particularly limited, and may be of a size or shape that can cover the entire face, or may be attached to a specific area such as under the eyes or around the mouth, and may be separated into two or more depending on the purpose or characteristics of the product. .

In the hydrogel patch of the present invention, the synthetic resin base layer may be an important element in realizing the characteristics of the invention.

The “synthetic resin” refers to a polymer material with plasticity obtained by reacting low-molecular-weight organic chemicals obtained through oil or natural gas using heating, etc., and generally has high formability, plasticity, and processability, and has a strong film. It is shiny and has low water absorption and water permeability.

Due to the smooth surface of the synthetic resin base layer, it is difficult to use it to create patch products because conventional hydrogels do not adhere strongly to it, but the hydrogel layer of the present invention can be firmly bonded to the synthetic resin base layer due to its excellent adhesive properties. .

At this time, the synthetic resin base layer may be a transparent film made of a light-transmissive material.

The “light transparency” refers to the property of light passing through the inside of a material. If light has the physical property of passing through a material without being scattered, the material allows visible light to pass through and has transparency.

The “transparent film” refers to a thin film that has light transparency. Due to the characteristics of the material, it has impermeability, impermeability, rigidity, toughness, elasticity, flexibility, transparency, etc., and has a smooth surface, so in the case of water-soluble hydrogel, the transparent film On the other hand, the hydrogel layer of the present invention can be firmly bonded to the transparent film while retaining the characteristics of a water-soluble hydrogel.

Referring to Figure 4, unlike conventional patch products, the base layer of the present invention uses a synthetic resin base layer made of a light-transmissive material, so it exhibits smooth and glossy surface characteristics while being light transparent and laminated at the bottom of the base layer. The color, pattern, and texture of the hydrogel layer can be visually conveyed.

In one embodiment, the synthetic resin base layer includes polyethylene (PE), polystyrene (PS), polyethylene terephthalate (PET), polypropylene (PP), thermoplastic polyurethane (TPU), polycarbonate (PC), and polycaprolactone. It may be manufactured from one or more selected from the group consisting of (PCL), polyacetal (POM), polyvinyl chloride (PVC), polyvinyl alcohol (PVA), polyamide (PA), and Teflon, but is not limited thereto, and has waterproof and Any synthetic resin material that has characteristics that fabric does not have, such as transparency, can be widely used.

At this time, the synthetic resin base layer may be subjected to post-processing surface treatment to further improve adhesion with the hydrogel layer. For example, adhesion may be improved through corona discharge treatment, but in addition, a post-processing process to improve adhesion may be performed. can be applied.

In addition, the synthetic resin base layer not only improves adhesion, but also considers product characteristics by applying sunscreen coating, primer treatment, graft polymerization, ozone irradiation, fire irradiation, ion irradiation, electron beam irradiation, laser irradiation, plasma irradiation, release treatment, backside treatment, etc. Various post-processing surface treatment processes such as electrification, laminating, glossy coating, matte coating, epoxy coating, and CR coating can be applied.

Meanwhile, the hydrogel layer is made of hydrogel and is in direct contact with the skin, and can be laminated on one side of the base layer.

The hydrogel layer is formed by crosslinking chains of hydrophilic polymers to form a three-dimensional network, and may be made of a polymer material that contains water but is insoluble in water. The hydrogel layer according to the invention is a hybrid gel containing insoluble synthetic polymers and has excellent adhesion, allowing it to efficiently deliver skin care ingredients while firmly adhering to the skin surface.

The hydrogel layer, unlike conventional high-viscosity hydrogels, can be processed into a predetermined pad shape, and has particularly excellent adhesion and elasticity, providing a pulling force to the skin surface to produce a lifting effect.

The hydrogel layer has both water-soluble and insoluble characteristics and has excellent adhesion and elasticity, so not only can it provide a pulling effect on skin tissue when attached to the skin, but it can also be strongly adhered to the synthetic resin base layer. The transparent film material can function as a base layer in relation to the hydrogel of the present invention.

In addition, the hydrogel layer has the characteristics of a water-soluble hydrogel and supplies various active ingredients along with moisture to the skin. The synthetic resin base layer is impermeable and suppresses evaporation of moisture, thereby maximizing the hydrogel's natural skin delivery effect. It can be.

The hydrogel layer may contain polyhydric alcohol, a chelating agent, a natural polymer gelling agent, and a synthetic polymer gelling agent, and has high adhesion, which is an advantage of an insoluble hydrogel patch, and a moisturizing feeling, which is an advantage of a water-soluble hydrogel patch. Can be implemented simultaneously.

The polyhydric alcohol plays a moisturizing role and may be, for example, one or more selected from the group consisting of glycerin, ethylene glycol, 1,3-butylene glycol, propylene glycol, dipropylene glycol, sorbitol, and xylitol. Although not limited, it may preferably be glycerin.

The chelating agent serves to induce a chelating effect on metal ions, for example, disodium EDTA, EDTA, sodium EDTA-2, calcium citrate, sodium citrate, organic acid salts thereof, These organic bases or mixtures thereof may be used, but are not limited thereto.

The natural polymer gelling agent is sufficient as a polymer that can form the skeleton of a hydrogel, for example, a group consisting of carrageenan, agar, carob gum, xanthan gum, gellan gum, algin, glucomannan, galactomannan, guar gum, and pluronic. It may be one or more selected from, but is not limited to.

The synthetic polymer gelling agent is used to improve usability by providing adhesion and elasticity, for example, polyacrylate or its salt, polymethacrylic acid, carboxyvinyl polymer, polyvinyl alcohol, polyacrylamide, polyethylene oxide. , polyethyleneimine, polyvinylpidolidone, methylcellulose, cellulose, carboxymethylcellulose, and hydroxy ethercellulose, but is not limited thereto.

The hydrogel layer may further include a synthetic polymer thickener.

The synthetic polymer thickener is intended to improve the adhesion and rigidity of the hydrogel and is composed of polyacrylic acid or ethylene/acrylic acid copolymer, ethylene/acrylic acid/VA copolymer, ethylene/calcium acrylate copolymer, and ethylene/sodium acrylate. It may be one or more selected from the group consisting of copolymer, acrylate/VP copolymer, acrylate/VA copolymer, acrylate copolymer, hydroxyethyl cellulose, and carboxyvinyl polymer, but is not limited thereto.

The synthetic polymer thickener is introduced to maintain the feeling of use and adhesion of the hydrogel at a high level while minimizing the decrease in moisture caused by excessively increasing the content of the synthetic polymer gelling agent. It is desirable to maintain the ratio of the synthetic polymer thickener at an appropriate level.

In one embodiment, the hydrogel layer may include 40 to 80 parts by weight of the natural polymer gelling agent, 30 to 60 parts by weight of the synthetic polymer gelling agent, and 100 to 400 parts by weight of the synthetic polymer thickener.

The natural polymer gelling agent forms the framework of the hydrogel and provides moisturizing and skin soothing effects by providing moisture to the skin. However, if the content is too low, it is difficult to maintain the gel form, and if the content is excessive, the viscosity and syneresis amount increase, making usability and adhesion difficult. may deteriorate.

The synthetic polymer gelling agent provides adhesion to the hydrogel layer and maintains an appropriate level of strength, but if the content is too low, the intended technical effect, such as lowering the elasticity of the gel, may not be realized, and if the content is excessive, hardening may occur. If there is a delay, marketability may deteriorate.

The synthetic polymer thickener is introduced together with the synthetic polymer gelling agent to improve adhesion and moisturizing, but if contained in excessive amounts, it may lower the physical properties by lowering the pH of the hydrogel.

If the ratio of the gelling agent and the synthetic polymer thickener in the hydrogel layer exceeds the appropriate level, the moisturizing feeling may be reduced or the rigidity and adhesion of the hydrogel may be reduced, so it is preferable to maintain the mixing ratio within the above range.

At this time, the pH of the hydrogel layer may be 3.5 to 6.5.

If the pH of the hydrogel layer is less than 3.5, the strength of the gel may be lowered, making it difficult to maintain its shape and the feeling of use may be reduced, and if the pH is more than 6.5, curing may not be smooth and the gel may not be properly formed.

Meanwhile, the hydrogel layer may further include one or more colorants.

The coloring material is used to provide a color effect to the hydrogel layer. The hydrogel layer is located at the bottom of the synthetic resin base layer, but the color, material, texture, etc. of the hydrogel layer are recognized even from the outside due to the light transparency of the support layer. can do.

Therefore, the hydrogel layer contains coloring materials having various characteristics, can exhibit certain aesthetic characteristics, and can implement various appearance characteristics through various types of coloring materials.

For example, various types of pigment components may be used as the coloring material, and design characteristics may be provided to the hydrogel layer through natural materials such as flowers.

In one embodiment, the colorant is dye; extender pigments including talc, mica, kaolin, calcium carbonate, mica, talc, kaolin, alumina, barium silicate, zeolite, muscovite, magnesium carbonate, and barium sulfate; coloring pigments including bengara, iron sulfate, black iron oxide, red iron oxide, chromium oxide, ultramarine blue, royal blue, and carbon black; White pigment containing titanium dioxide and zinc oxide; Organic pigments containing tar colorants; lake; Pearl pigments including titanium dioxide, titanium mica, iron titanate and titanium oxide coated mica, silica, tin oxide, and ferric ferrocyanide; and natural pigments including beta-carotene, cartamine, and cochineal; but are not limited thereto, and various materials may be used to implement the intended aesthetic characteristics.

The content of the colorant is not particularly limited and can be adjusted appropriately as needed, but is preferably included in 0.1 to 20% by weight of the total weight of the composition.

In one embodiment, the hydrogel layer may be composed of a first hydrogel layer and a second hydrogel layer containing distinct colorants.

Since the hydrogel patch can expose the design elements of the hydrogel layer to the outside when applied to the skin, a more characteristic exterior design can be realized by applying one or more hydrogel layers with conflicting concepts.

Referring to Figure 3, the first hydrogel layer and the second hydrogel layer each have distinct colors that contrast or harmonize with each other, or contain colorants with different textures, thereby providing marketability that a single hydrogel layer cannot achieve. You can.

The hydrogel patch can implement design characteristics that are completely different from conventional patches using fabric by configuring the first hydrogel layer and the second hydrogel layer in various colors, patterns, and combinations.

The hydrogel layer contains a pH adjuster; and a cross-linking agent.

The pH adjuster includes tartaric acid, urea, ammonia, ammonium phosphate, diethanolamine, dimethylethanolamine, sodium bicarbonate, sodium hydrogel carbonate, triethylamine, triethanolamine, polyethyleneimine, calcium hydroxide, potassium hydroxide, One or more may be selected from the group consisting of glycyrrhizic acid, ascorbic acid, salicylic acid, stearic acid, amino acids, azelaic acid, asiatic acid, and oxalic acid, but are not limited thereto.

The crosslinking agent is preferably a multivalent metal salt, for example, aluminum glycinate, aluminum hydroxide, aluminum hydroxide gel, hydrous aluminum silicate, kaolin, aluminum acetate, aluminum lactate, aluminum stearate, calcium chloride, magnesium chloride, aluminum chloride, meta. It may be one or more selected from the group consisting of magnesium aluminate silicate and magnesium aluminate silicate, but is not limited thereto.

The hydrogel layer of the present invention may, if necessary, contain additives such as preservatives, fragrances, surfactants, skin active ingredients, etc., and the types of these additives are not particularly limited.

The preservatives include capryl glycol, paraoxybenzoic acid alkyl ester, benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, phenoxyethanol, paraben, pentanediol, benzoic acid, salicylic acid, dihydroacetic acid or its salts, ethylhexylglycerin, 1 , 2-hexanediol, caprylic glycoltroporone, p-oxybenzoic acid ester, 3-trifluoromethyl-4,4'-dichlorocarbanilide, and 2,4,4'-trichloro-2-hydroxy One or more may be selected from the group consisting of sidiphenyl ether, but are not limited thereto.

The surfactant includes polyhydric alcohols including glyceryl monostearate, polyglyceryl-4 isostearate, sorbitan monostearate, and sugar ester monostearate; Polyoxyethylenemethylpolysiloxanes including PEG-8 dimethicone, PEG-10 dimethicone, PEG-9 methyletherdimethicone, PEG-3 dimethicone and PEG-11 methyletherdimethicone, which are esters of fatty acids. copolymer; Poly(oxyethylene·oxypropylene)methylpolysiloxane copolymer including PEG/PPG-20/20 butyl ether dimethicone and PEG/PPG 20/20 dimethicone; and alkyl chain/silicon chain branched poly(oxyethylene·oxypropylene)methylpolysiloxane copolymer including cetyl PEG/PPG 10/1-dimethicone and lauryl PEG-9 polydimethylsiloxyethyldimethicone. It may be one or more selected from the group, but is not limited thereto.

The skin active ingredients may be, for example, one or more selected from the group consisting of arbutin, niacinamide, vitamin C, vitamin B5, vitamin E, retinol, coenzyme Q10, adenosine, and natural extracts, but are not limited thereto.

The natural extracts include aloe, green tea, ginseng, red ginseng, wood vinegar, pine needles, ginkgo leaves, propolis, mulberry leaves, silkworms, kakadu plums, camu camu, Yassa palm, squalane, caviar, broccoli, blueberries, witch hazel, acerola, Chlorella, mangosteen, guava, soybean sprouts, carrots, caffeine, hamamelis, spirulina, salmon roe, gamtae, giant kelp, dried seaweed, portulaca, sea lettuce, agar agar, mulberry root, raspberry, raspberry, hijiki, radish, edelweiss, It may be one or more selected from the group consisting of chamomile, lavender, peppermint, eucalyptus, lemon balm, oregano, tea tree, goldenrod, Houttuynia cordata, and sea buckthorn extract, but is not limited thereto.

The hydrogel layer can be manufactured in the form of a pad that can be easily used by attaching it to a specific part of the body in a solid or semi-solid formulation depending on the composition ratio, and can be implemented in a specific desired shape and thickness depending on the application area and use.

The shape, size, and thickness of the hydrogel layer are not particularly limited, but may be manufactured to have a thickness of, for example, 0.05 to 10.0 mm.

If the hydrogel layer is less than 0.05 mm, it may be easily torn or the functionality may be partially reduced due to lack of active ingredients or moisture content, and if it is more than 10.0 mm, manufacturing costs may increase or the feeling of use may be reduced when attached to a body part due to the weight. .

The present invention will be described in further detail through the following examples, but it is obvious that the present invention is not limited by the following examples.

Manufacturing example

Patches of Examples and Comparative Examples were prepared using the ingredients shown in Tables 1 and 2 below.

After mixing the polyhydric alcohol, chelating agent, pH adjuster, and solvent components at a temperature of 80 to 90°C, add and mix the natural polymer gelling agent, synthetic polymer gelling agent, synthetic polymer thickener, and other remaining additive ingredients to obtain hydro. A gel mixture was obtained.

A hydrogel patch was manufactured by coating this on a base layer molded into a form attachable to the face.

In the production of hydrogel, disodium EDTA was used as a chelating agent, glycerin was used as a polyhydric alcohol, tartaric acid was used as a pH adjuster, and aluminum glycinate was used as a cross-linking agent.

In addition, a mixture of agar, cellulose gum, and xanthan gum was used as a natural polymer gelling agent, sodium polyacrylate was used as a synthetic polymer gelling agent, and polyacrylic acid was used as a synthetic polymer thickener.

TPU film was used as the synthetic resin base layer, and polyester fiber was used as the fabric.

In the Example, a patch was manufactured using a synthetic resin base layer, and in the Comparative Example, some of the components of the present invention were excluded or the base layer was replaced with fabric to compare the quality of the product and the skin improvement effect of using the patch.

[Content (parts by weight)] division Example One 2 3 4 5 6 Hydrogel layer Purified water remaining amount remaining amount remaining amount remaining amount remaining amount remaining amount Chelating agent 2.0 2.0 2.0 2.0 2.0 2.0 pH regulator 0.3 0.3 0.3 0.3 0.3 0.3 Polyhydric alcohol 30.0 30.0 30.0 30.0 30.0 30.0 Natural polymer gelling agent 100 6.0 6.0 6.0 6.0 6.0 Synthetic polymer gelling agent 150 4.5 4.5 4.5 4.5 4.5 Synthetic polymer thickener - 250 100 400 50 500 crosslinking agent 0.2 0.2 0.2 0.2 0.2 0.2 base layer synthetic resin O O O O O O fabric - - - - - -

[Content (parts by weight)] division Comparative example One 2 3 4 5 6 Hydrogel layer Purified water remaining amount remaining amount remaining amount remaining amount remaining amount remaining amount Chelating agent 2.0 2.0 2.0 2.0 2.0 2.0 pH regulator 0.3 0.3 0.3 0.3 0.3 0.3 Polyhydric alcohol 30.0 30.0 30.0 30.0 30.0 30.0 Natural polymer gelling agent 250 - - 100 6.0 6.0 Synthetic polymer gelling agent - 250 100 150 4.5 4.5 Synthetic polymer thickener - - 150 - 250 250 crosslinking agent 0.2 0.2 0.2 0.2 0.2 0.2 base layer synthetic resin O O O - - - fabric - - - O O -

Experimental Example 1: Sensory evaluation

Sensory evaluation was determined by calculating the average using a 5-point scale.

Subjects were asked to observe the characteristics of the hydrogel patches of Examples and Comparative Examples and evaluate their quality.

According to the symbol scale of 5 points, 5 points were given if the quality was the best, and 1 point was given if the quality was the poorest.

The experimental results of the hydrogel patch's adhesion, base layer bonding power, and usability were rated from 1 (poor) to 5 (excellent), and the results are shown in Table 3.

Adhesion was evaluated to determine whether it was firmly fixed to the body part.

The bonding strength of the base layer was evaluated to determine whether the hydrogel layer and the base layer were strongly adhered without being easily separated.

Usability was evaluated by the level of discomfort caused by water syneresis or activity after attachment, and the feeling of moisture after attachment.

division Adhesion Base layer bonding force usability overall product quality Example 1 3.5 3.6 3.5 3.3 Example 2 4.2 4.5 4.4 4.4 Example 3 4.0 4.3 4.1 4.2 Example 4 4.1 4.4 4.3 4.3 Example 5 3.7 3.8 3.9 3.8 Example 6 3.5 3.9 3.7 3.7 Comparative Example 1 1.7 1.3 1.2 1.4 Comparative Example 2 2.7 2.3 2.8 2.6 Comparative Example 3 3.2 3.5 2.5 3.1 Comparative Example 4 3.4 3.0 3.0 3.0 Comparative Example 5 4.1 3.7 3.2 3.5 Comparative Example 6 4.2 - 2.8 3.2

Referring to Table 3, Example 1, which includes a natural polymer gelling agent and a synthetic polymer gelling agent and a laminated synthetic resin base layer, and Examples 2 to 6, which further include a synthetic polymer thickener, include some of them. Compared to Comparative Examples 1 to 6, which were not used, the overall quality, including adhesion, base layer bonding power, and applicability, was evaluated as excellent.

Specifically, in Example 2, the overall quality, such as adhesion, was significantly improved by including more synthetic polymer thickener compared to Example 1, and in Comparative Examples 3 to 6, some quality was changed by varying the content of the synthetic polymer thickener. .

In particular, in Examples 5 and 6, too little or too much synthetic polymer thickener was included, resulting in some deterioration in product quality.

In addition, in Comparative Examples 1 to 3, a synthetic resin base layer was laminated, but there was a problem in that the properties intended by the present invention were not realized because it did not contain a natural polymer gelling agent or contained only a natural polymer gelling agent.

In the case of Comparative Examples 4 and 5, the use of fabric as a base layer resulted in a problem of deterioration of product properties, including usability, compared to the case where a synthetic resin base layer was used.

In the case of Comparative Example 6, a separate base layer was not included, so there was a problem in that the benefits due to the base layer were not realized.

The above results show that when natural polymer gelling agent and synthetic polymer gelling agent are mixed in an appropriate ratio, adhesion and adhesive properties are strengthened, allowing synthetic resin materials to be used as a base layer, and adhesion and usability can be significantly improved through synthetic resin thickeners. suggests.

Experimental Example 2: Evaluation of skin moisturizing and lifting effects

The hydrogel patches of Examples and Comparative Examples were applied daily to the face of an adult woman in the experimental group, and the skin lifting effect was evaluated using a Moire method measurement device, using Aram Huvis' 'Aramo TS-II' device. So, the effect of improving skin moisture was measured.

The skin lifting value (R, angle) was measured before use of the product and 3 weeks after use, and the lifting improvement rate was expressed as a percentage value. The moisture sensation was calculated as the moisture sensation after 3 weeks of using the product and the moisture sensation before use. Differences were evaluated (Table 4).

Generally, in the case of moisture evaluation, a score of 39 or less means insufficient moisture, and a score of about 45 to 55 means good moisture status.

division Lifting improvement rate (%) Difference in moisture before and after application Example 1 16.2 9.5 Example 2 23.8 13.2 Example 3 21.3 12.4. Example 4 22.5 11.9 Example 5 18.5 10.7 Example 6 19.8 9.3 Comparative Example 1 5.2 4.5 Comparative Example 2 2.4 1.4 Comparative Example 3 2.6 1.2 Comparative Example 4 14.6 5.6 Comparative Example 5 19.5 9.3 Comparative Example 6 19.3 8.9

Referring to Table 4, Example 1, which includes a natural polymer gelling agent and a synthetic polymer gelling agent and a laminated synthetic resin base layer, and Examples 2 to 6, which further include a synthetic polymer thickener, include some of them. It was evaluated that the skin lifting effect and skin moisturizing effect were excellent compared to Comparative Examples 1 to 6 that did not use it.

Specifically, in Example 2, the skin lifting effect and skin moisturizing effect were significantly improved by further including a synthetic polymer thickener compared to Example 1.

In Comparative Examples 3 to 6, some skin improvement effects were different by varying the content of the synthetic polymer thickener, and in Examples 5 and 6, the functionality was partially reduced because too little or too much of the synthetic polymer thickener was included.

In addition, in Comparative Examples 1 to 3, a synthetic resin base layer was laminated, but it did not contain a natural polymer gelling agent or contained only a natural polymer gelling agent, so the lifting effect due to use was reduced or the skin moisturizing effect was significantly reduced.

In Comparative Examples 4 to 6, fabric was used as a base layer or a separate base layer was not included, so the moisture in the hydrogel layer evaporated easily and the skin moisturizing effect was somewhat reduced.

The above results show that the skin lifting effect can be significantly improved by simultaneously including a natural polymer gelling agent, a synthetic polymer gelling agent, and a synthetic polymer thickening agent, and the synthetic resin base layer in the hydrogel patch improves the skin moisturizing effect by suppressing evaporation of moisture. It suggests that it can be done.

The description of the present invention described above is for illustrative purposes, and those skilled in the art will understand that the present invention can be easily modified into other specific forms without changing the technical idea or essential features of the present invention. will be. Therefore, the embodiments described above should be understood in all respects as illustrative and not restrictive. For example, each component described as single may be implemented in a distributed manner, and similarly, components described as distributed may also be implemented in a combined form.

The scope of the present invention is indicated by the claims described below, and all changes or modified forms derived from the meaning and scope of the claims and their equivalent concepts should be construed as being included in the scope of the present invention.

Claims (9)

In a hydrogel patch that can flexibly implement aesthetic characteristics,
A synthetic resin base layer made of a light-transmissive material; and
It includes a hydrogel layer laminated on one side of the synthetic resin base layer,
The hydrogel layer is
coloring material,
polyhydric alcohol,
40 to 80 parts by weight of natural polymer gelling agent,
From the group consisting of polyacrylate or its salt, polymethacrylic acid, carboxyvinyl polymer, polyvinyl alcohol, polyacrylamide, polyethylene oxide, polyethyleneimine, polyvinylpidolidone, carboxymethylcellulose, and hydroxy ethercellulose. 30 to 60 parts by weight of at least one selected synthetic polymer gelling agent and
Polyacrylic acid or ethylene/acrylic acid copolymer, ethylene/acrylic acid/VA copolymer, ethylene/calcium acrylate copolymer, ethylene/sodium acrylate copolymer, acrylate/VPicocopolymer, acrylate/VA copolymer, Containing 100 to 400 parts by weight of at least one synthetic polymer thickener selected from the group consisting of acrylate copolymer, hydroxyethylcellulose, and carboxyvinyl polymer,
The hydrogel layer is a solid or semi-solid formulation that is manufactured in the form of a pad that can be attached to a specific part of the body and is directly and firmly bonded to the synthetic resin base layer made of the light-transmissive material. According to paragraph 1,
A hydrogel patch, wherein the pH of the hydrogel layer is 3.5 to 6.5. delete delete delete According to paragraph 1,
The synthetic resin base layer includes polyethylene (PE), polystyrene (PS), polyethylene terephthalate (PET), polypropylene (PP), thermoplastic polyurethane (TPU), polycarbonate (PC), polycaprolactone (PCL), and polyacetal. A hydrogel patch manufactured from one or more selected from the group consisting of (POM), polyvinyl chloride (PVC), polyvinyl alcohol (PVA), polyamide (PA), and Teflon. delete According to paragraph 1,
The colorant is dye; one or more extender pigments of talc, mica, kaolin, calcium carbonate, mica, talc, kaolin, alumina, barium silicate, zeolite, muscovite, magnesium carbonate, and barium sulfate; one or more coloring pigments selected from the group consisting of bengara, iron sulfate, black iron oxide, red iron oxide, chromium oxide, ultramarine blue, royal blue, and carbon black; One or more white pigments selected from titanium dioxide and zinc oxide; Organic pigments containing tar colorants; lake; Pearl pigments of one or more of titanium dioxide, titanium mica, iron titanate and titanium oxide coated mica, silica, tin oxide, and ferric ferrocyanide; and one or more natural pigments selected from beta-carotene, cartamine, and cochineal. A hydrogel patch selected from the group consisting of one or more natural pigments. According to paragraph 1,
A hydrogel patch, wherein the hydrogel layer consists of a first hydrogel layer and a second hydrogel layer containing mutually distinct colorants.