KR102583062B1 - 동종중합체 인코딩된 핵산 메모리 - Google Patents

동종중합체 인코딩된 핵산 메모리 Download PDF

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KR102583062B1
KR102583062B1 KR1020197038747A KR20197038747A KR102583062B1 KR 102583062 B1 KR102583062 B1 KR 102583062B1 KR 1020197038747 A KR1020197038747 A KR 1020197038747A KR 20197038747 A KR20197038747 A KR 20197038747A KR 102583062 B1 KR102583062 B1 KR 102583062B1
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nucleic acid
homopolymer
strand
data
tracks
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KR20200027927A (ko
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윌리엄 제이. 에프카비치
매튜 티. 홀덴
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몰레큘러 어셈블리즈, 인크.
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    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
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    • G06N3/00—Computing arrangements based on biological models
    • G06N3/12—Computing arrangements based on biological models using genetic models
    • G06N3/123—DNA computing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/20—Heterogeneous data integration
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    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11B—INFORMATION STORAGE BASED ON RELATIVE MOVEMENT BETWEEN RECORD CARRIER AND TRANSDUCER
    • G11B7/00—Recording or reproducing by optical means, e.g. recording using a thermal beam of optical radiation by modifying optical properties or the physical structure, reproducing using an optical beam at lower power by sensing optical properties; Record carriers therefor
    • G11B7/24—Record carriers characterised by shape, structure or physical properties, or by the selection of the material
    • G11B7/241—Record carriers characterised by shape, structure or physical properties, or by the selection of the material characterised by the selection of the material
    • G11B7/242—Record carriers characterised by shape, structure or physical properties, or by the selection of the material characterised by the selection of the material of recording layers
    • G11B7/244—Record carriers characterised by shape, structure or physical properties, or by the selection of the material characterised by the selection of the material of recording layers comprising organic materials only
    • G11B7/245—Record carriers characterised by shape, structure or physical properties, or by the selection of the material characterised by the selection of the material of recording layers comprising organic materials only containing a polymeric component
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C11/00—Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor
    • G11C11/54—Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor using elements simulating biological cells, e.g. neuron
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C13/00—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/0002—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using resistive RAM [RRAM] elements
    • G11C13/0009—RRAM elements whose operation depends upon chemical change
    • G11C13/0014—RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material
    • G11C13/0019—RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material comprising bio-molecules
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C13/00—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/02—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using elements whose operation depends upon chemical change
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C13/00—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/04—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using optical elements ; using other beam accessed elements, e.g. electron or ion beam
    • G11C13/048—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using optical elements ; using other beam accessed elements, e.g. electron or ion beam using other optical storage elements
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C7/00—Arrangements for writing information into, or reading information out from, a digital store
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C7/00—Arrangements for writing information into, or reading information out from, a digital store
    • G11C7/10—Input/output [I/O] data interface arrangements, e.g. I/O data control circuits, I/O data buffers
    • G11C7/1006—Data managing, e.g. manipulating data before writing or reading out, data bus switches or control circuits therefor
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B50/00—ICT programming tools or database systems specially adapted for bioinformatics
    • G16B50/30—Data warehousing; Computing architectures

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  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Theoretical Computer Science (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Wood Science & Technology (AREA)
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  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Medical Informatics (AREA)
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  • Evolutionary Computation (AREA)
  • Computing Systems (AREA)
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  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Bioethics (AREA)
  • Databases & Information Systems (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Computer Hardware Design (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020197038747A 2017-05-31 2018-05-31 동종중합체 인코딩된 핵산 메모리 Active KR102583062B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762513111P 2017-05-31 2017-05-31
US62/513,111 2017-05-31
PCT/US2018/035365 WO2018222853A1 (en) 2017-05-31 2018-05-31 Homopolymer encoded nucleic acid memory

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KR20200027927A KR20200027927A (ko) 2020-03-13
KR102583062B1 true KR102583062B1 (ko) 2023-09-25

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US (1) US10982276B2 (enExample)
EP (1) EP3630350A4 (enExample)
JP (1) JP7277054B2 (enExample)
KR (1) KR102583062B1 (enExample)
WO (1) WO2018222853A1 (enExample)

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US10774366B2 (en) 2016-03-11 2020-09-15 President And Fellows Of Harvard College Method of making polynucleotides using closed-loop verification
US10870872B2 (en) 2016-04-04 2020-12-22 President And Fellows Of Harvard College Enzymatic nucleic acid synthesis
US10745814B2 (en) 2016-05-09 2020-08-18 President And Fellows Of Harvard College Enzymatic nucleic acid synthesis
GB2563105B (en) 2016-11-16 2022-10-19 Catalog Tech Inc Nucleic acid-based data storage
US11612873B2 (en) * 2017-05-31 2023-03-28 Molecular Assemblies, Inc. Homopolymer encoded nucleic acid memory
US11174512B2 (en) 2017-05-31 2021-11-16 Molecular Assemblies, Inc. Homopolymer encoded nucleic acid memory
GB201801768D0 (en) 2018-02-02 2018-03-21 Oxford Nanopore Tech Ltd Synthesis method
AU2019236289B2 (en) 2018-03-16 2024-12-05 Catalog Technologies, Inc. Chemical methods for nucleic acid-based data storage
US11339423B2 (en) * 2018-03-18 2022-05-24 Bryan Bishop Systems and methods for data storage in nucleic acids
EP3826762A1 (en) 2018-07-23 2021-06-02 DNA Script Massively parallel enzymatic synthesis of nucleic acid strands
AU2019315604B2 (en) 2018-08-03 2025-04-17 Catolog Technologies, Inc Systems and methods for storing and reading nucleic acid-based data with error protection
SG11202105441WA (en) 2018-12-13 2021-06-29 Dna Script Direct oligonucleotide synthesis on cells and biomolecules
GB201821155D0 (en) * 2018-12-21 2019-02-06 Oxford Nanopore Tech Ltd Method
WO2020219853A1 (en) * 2019-04-24 2020-10-29 Molecular Assemblies, Inc. Homopolymer encoded nucleic acid memory
CA3139819A1 (en) 2019-05-09 2020-11-12 Catalog Technologies, Inc. Data structures and operations for searching, computing, and indexing in dna-based data storage
CN112673428A (zh) * 2019-05-31 2021-04-16 伊鲁米那股份有限公司 存储设备、系统和方法
EP4110940B1 (en) * 2020-02-25 2024-03-27 DNA Script Method and apparatus for enzymatic synthesis of polynucleotides
CN111489791B (zh) * 2020-04-07 2023-05-26 中国科学院重庆绿色智能技术研究院 固态纳米孔高密度编码dna数字存储读取方法
AU2021341940A1 (en) * 2020-09-08 2023-03-30 Catalog Technologies, Inc. Systems and methods for writing by sequencing of nucleic acids
CA3227373A1 (en) * 2021-07-28 2023-02-02 Eric Kool Compositions, systems, and methods for nucleic acid data storage
US12014256B2 (en) * 2022-01-12 2024-06-18 Dell Products L.P Polysaccharide archival storage

Citations (1)

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US20170017436A1 (en) * 2015-07-13 2017-01-19 President And Fellows Of Harvard College Methods for Retrievable Information Storage Using Nucleic Acids

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AU2011226792A1 (en) 2010-06-11 2012-01-12 Life Technologies Corporation Alternative nucleotide flows in sequencing-by-synthesis methods
GB2500360B (en) 2010-12-22 2019-10-23 Genia Tech Inc Nanopore-based single DNA molecule characterization, identification and isolation using speed bumps
CN107828877A (zh) 2012-01-20 2018-03-23 吉尼亚科技公司 基于纳米孔的分子检测与测序
EP2875458A2 (en) 2012-07-19 2015-05-27 President and Fellows of Harvard College Methods of storing information using nucleic acids
US10683536B2 (en) 2013-04-02 2020-06-16 Molecular Assemblies, Inc. Reusable initiators for synthesizing nucleic acids
JP6448097B2 (ja) 2013-10-15 2019-01-09 モレキュラー アセンブリーズ， インコーポレイテッド 核酸を合成するための方法および装置
EP3368692B1 (en) 2015-10-29 2021-07-21 Temple University Of The Commonwealth System Of Higher Education Modification of 3' terminal ends of nucleic acids by dna polymerase theta
WO2017151680A2 (en) * 2016-02-29 2017-09-08 Dodo Omnidata, Inc. Methods, compositions, and devices for information storage
GB2563105B (en) * 2016-11-16 2022-10-19 Catalog Tech Inc Nucleic acid-based data storage
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EP3630350A1 (en) 2020-04-08
US20190040459A1 (en) 2019-02-07
JP7277054B2 (ja) 2023-05-18
US10982276B2 (en) 2021-04-20
JP2020522257A (ja) 2020-07-30
EP3630350A4 (en) 2021-03-31
WO2018222853A1 (en) 2018-12-06
KR20200027927A (ko) 2020-03-13

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