KR102524972B1 - Composition for improving muscle strength containing ashwagandha extract and method for manufacturing the same - Google Patents

Abstract

The present invention relates to a composition for improving muscle strength containing ashwagandha extract as an active ingredient and a method for preparing the same. The present invention can provide a composition for improving muscle strength comprising an extract of ashwagandha root and an extract of at least one of ashwagandha leaves and stems as an active ingredient.

Description

Composition for improving muscle strength containing ashwagandha extract and method for manufacturing the same

The present invention relates to a composition for improving muscle strength containing ashwagandha extract as an active ingredient and a method for preparing the same.

In order to improve physical strength, it is necessary to consume ergogenic aids, including not only diet and scientific training, but also techniques and equipment. In particular, nutritional energy supplements enable you to obtain necessary nutrients and energy quickly and efficiently, and act as a positive factor that can improve exercise performance by delaying the accumulation of fatigue and exhaustion of energy due to exercise.

However, modern office workers who are exposed to physical and mental fatigue due to lack of exercise and stress, but find it difficult to exercise and leisure activities due to time and economic reasons, indiscriminately consume and abuse many functional foods that have not been scientifically verified, and become commonplace in daily sports. The cases of damage caused by side effects caused by sudden exercise are steadily increasing.

Since a study was reported that steroid administration, a representative example of drug use, causes skeletal muscle wasting, research on substitutes for drugs such as steroids has been actively conducted. In the field of sports physiology, many studies are being conducted on ergogenic aids to improve muscle strength and exercise performance, and in particular, studies on the effects of protein supplements and amino acids on muscle strength and exercise performance are being actively conducted. According to these studies, in studies on the effect of weight training and protein supplements, it has been reported that muscle strength is improved when an appropriate exercise program is combined with protein supplements. Accumulation of basic data, etc., is very insufficient.

The present invention aims to solve the above problems and other problems related thereto.

An object of the present invention is to provide a composition containing an ashwagandha extract as an active ingredient and a method for producing the same, in which the functional component for improving muscle strength is enhanced.

In addition, it is an object of the present invention to provide a manufacturing method for increasing the content of a muscle strength improving functional component by utilizing non-edible parts of ashwagandha.

In order to achieve the above object, the present invention can provide a composition for improving muscle strength comprising an extract of ashwagandha root and at least one extract of ashwagandha leaf and stem as an active ingredient.

In one embodiment, a weight ratio between an extract of ashwagandha root and an extract of at least one of ashwagandha leaves and stems may be 8.5:1 to 9.5:1.

In one embodiment, the active ingredient may be an extract of ashwagandha root and an extract of ashwagandha leaf.

In one embodiment, the composition may include 7.2 to 10.8 mg of Withaperin A based on 1 g of the composition.

In one embodiment, the composition may promote an increase in the thickness of myotube cells.

In one embodiment, the composition may include a food composition or a pharmaceutical composition.

In addition, the present invention may provide a method for preparing a composition for improving muscle strength containing an ashwagandha extract. In the present invention, ashwagandha roots and ashwagandha leaves are mixed in a weight ratio of 13.4: 1 to 14.9: 1 to prepare a raw material mixture, after mixing the raw material mixture with an ethanol aqueous solution of 40 to 50% concentration, 15 immersing for more than an hour, extracting at a temperature of 40 to 60 ° C. for 4 to 6 hours to prepare an ashwagandha extract, and concentrating and drying the ashwagandha extract to prepare a composition for improving muscle strength It is possible to provide a method for producing a composition for improving muscle strength comprising.

According to the present invention, while minimizing the toxicity of the ashwagandha extract, it is possible to increase the withapherin content. Through this, the present invention can provide a composition for improving muscle strength containing an ashwagandha extract that helps improve muscle strength.

1 is a photograph showing the increase in the thickness of myotubes according to the treatment of the ashwagandha extract of the present invention.
Figure 2 is a graph showing the amount of increase in the thickness of myotubes according to the treatment of the ashwagandha extract of the present invention.
Figure 3 is a graph showing the toxicity evaluation results for the ashwagandha extract of the present invention.
Figure 4a is a graph showing the yield of ashwagandha root extract, the contents of withapherin A and withanolide A according to the ethanol concentration of the extraction solvent.
Figure 4b is a graph showing the yield of ashwagandha leaf extract, the contents of withapherin A and withanolide A according to the ethanol concentration of the extraction solvent.
Figure 5a is a graph showing the yield of ashwagandha root extract, the contents of withapherin A and withanolide A according to the extraction temperature.
Figure 5b is a graph showing the yield of ashwagandha leaf extract, the contents of withapherin A and withanolide A according to the extraction temperature.
Figure 6a is a graph showing the yield of ashwagandha root extract, the contents of withapherin A and withanolide A according to the extraction time.
Figure 6b is a graph showing the yield of ashwagandha leaf extract, the contents of withapherin A and withanolide A according to the extraction time.
7 is a graph showing the yield of ashwagandha root extract, the contents of withapherin A and withanolide A according to grinding conditions.
8 is a graph showing the yield of ashwagandha root and leaf extracts, the contents of withapherin A and withanolide A according to the presence or absence of immersion.

Hereinafter, the embodiments disclosed in this specification will be described in detail with reference to the accompanying drawings, but the same reference numerals will be assigned to the same or similar components regardless of reference numerals, and overlapping descriptions thereof will be omitted. In addition, in describing the embodiments disclosed in this specification, if it is determined that a detailed description of a related known technology may obscure the gist of the embodiment disclosed in this specification, the detailed description thereof will be omitted. In addition, the accompanying drawings are only for easy understanding of the embodiments disclosed in this specification, the technical idea disclosed in this specification is not limited by the accompanying drawings, and all changes included in the spirit and technical scope of the present invention , it should be understood to include equivalents or substitutes.

Terms including ordinal numbers, such as first and second, may be used to describe various components, but the components are not limited by the terms. These terms are only used for the purpose of distinguishing one component from another.

Singular expressions include plural expressions unless the context clearly dictates otherwise.

In this specification, terms such as "comprise" or "having" are intended to indicate that there is a feature, number, step, operation, component, or combination thereof described in the specification, but one or more other features or numbers However, it should be understood that it does not preclude the presence or addition of steps, operations, components, or combinations thereof.

The present invention relates to an ashwagandha extract containing a large amount of Withaferrin A lactone-based component, which is a functional component for improving muscle strength, and a method for preparing the same.

In the present specification, 'ashwagandha extract' refers to a composition obtained by applying physical, chemical, biochemical, and biotechnological methods to ashwagandha roots, leaves, and stems. In addition, the ashwagandha extract is a mixture of each extract of the ashwagandha root, leaf, and stem, or a mixture of at least two of the ashwagandha root, leaf, and stem, followed by physical, chemical, biochemical, or bioengineering methods. It may be a composition obtained by applying the like. On the other hand, ashwagandha extract may be in the form of a dried powder, but is not limited thereto.

In the present specification, the term 'composition for muscle strength improvement' refers to a food group or food composition that has added value so that the function of the food acts for a specific purpose by using physical, biochemical, or bioengineering methods, etc. , food designed and processed to sufficiently express the body's regulatory functions related to disease prevention and recovery.

In the present specification, the composition for improving muscle strength includes various foods, beverages, gum, tea vitamin complexes, functional foods, and the like. Furthermore, the present invention provides various nutrients, vitamins, minerals (electrolytes), flavors such as synthetic flavors and natural flavors, colorants and fillers, pectic acid and its salts, alginic acid and its salts, organic acids, protective colloidal thickeners, pH It may contain regulators, stabilizers, preservatives, glycerin, alcohol, carbonation agents used in carbonated beverages, and the like, and the above components may be used independently or in combination. The components may be added in an appropriate amount within a range that does not impair the muscle strength improving function of the ashwagandha extract according to the present invention. For example, the component may be included within 50% by weight based on the weight of the solid content of the ashwagandha extract.

In addition, the composition for improving muscle strength may include food additives or pharmaceutical supplements acceptable for food or pharmaceutical purposes, and may further include appropriate carriers, excipients, and diluents commonly used in the preparation of compositions for improving muscle strength. can

Compositions for improving muscle strength in the form of beverages, granules, tablets, powders, pills, and capsules are easy to carry and can be easily consumed anytime, anywhere.

Hereinafter, a method for preparing a composition for improving muscle strength according to the present invention will be described in detail.

The manufacturing method according to the present invention includes (S1) preparing a raw material mixture, (S2) preparing an ashwagandha extract by mixing the raw material mixture and an extraction solution, and (S3) concentrating the ashwagandha extract. can include

Step (S1)

In step S1, a raw material mixture may be prepared.

The raw material mixture may be a mixture of at least one of ashwagandha root, ashwagandha leaf and stem.

In preparing the raw material mixture, each of the ashwagandha roots, leaves and stems may be pulverized and then mixed in a predetermined weight ratio, or ashwagandha roots, leaves and stems may be mixed in a predetermined weight ratio and then pulverized.

In one embodiment, the average particle diameter of the coarsely pulverized mixture may be 1 to 10 cm, and the average particle diameter of the non-pulverized mixture may be around 1 cm.

On the other hand, the ratio of the sum of the weight of the ashwagandha root and the weight of the ashwagandha leaves and stems may be 13.4: 1 to 14.9: 1. Here, the weight ratio is the weight between the ashwagandha root extract and at least one extract of the ashwagandha leaf and stem after preparing the extract from the ashwagandha root and preparing the extract from at least one of the ashwagandha leaf and stem. It is a mixing ratio of raw materials such that the ratio is 8.5:1 to 9.5:1. The mixing ratio of the raw materials may vary depending on the extraction yield of each raw material.

For example, based on the raw material extraction yield described in Table 2 described later, the mixing weight ratio of the raw material mixture such that the weight ratio between the ashwagandha root extract and the ashwagandha leaf extract is 9: 1 is 14.15 (root): It can be 1 (leaf).

If the weight ratio of the ashwagandha root in the raw material mixture is too high, it is difficult to expect the effect of enhancing the withtaperin A component of the ashwagandha extract. In addition, when the weight ratio of ashwagandha leaves and stems in the raw material mixture is too high, it is difficult to ingest the ashwagandha extract due to toxicity.

Step (S2)

In step S2, mixing the extraction solution with the raw material mixture is performed.

The extraction solution may be a mixture of water and ethanol.

The weight ratio of water and ethanol in the extraction solution may be 60:40 to 40:60. As the alcohol ratio in the extraction solution increases, the yield and the content of the indicator component increase, but when the alcohol content is above a certain level, safety during the manufacturing process may decrease. Preferably, the alcohol content of the extraction solution is preferably 40%.

In one embodiment, the extraction solution may be alcohol having an alcohol content of 40 to 50%.

On the other hand, after mixing the raw material mixture and the extraction solution, a step of immersing for 15 hours or more may be performed.

Thereafter, an extraction step may proceed. The extraction step is performed at a temperature of 40 to 60° C. and may be performed for 4 to 6 hours.

In one embodiment, the extraction step may be performed by putting ashwagandha roots and leaves in an extraction container, adding 40% alcohol, immersing for about 15 hours, and then putting them in a water bath or heating mantle.

In another embodiment, the extraction step may be performed by immersing Ashwagandha roots and leaves in 40% alcohol in a temperature-controlled extraction tank and then applying heat.

When the extraction is performed in the above temperature range, the yield and the content of the indicator component are the highest. Specifically, when the extraction is performed at 50 ° C., the yield and the content of the indicator component are the highest.

On the other hand, when the extraction is performed in the above time range, the yield and the content of the indicator component are the highest. Specifically, when the extraction is performed for 4 hours, the yield and the content of the indicator component are the highest.

Meanwhile, the extracted ashwagandha extract may be filtered through a separate filter. In one embodiment, the extract may be filtered through Whatman filter paper.

Step (S3)

In step S3, a step of concentrating the ashwagandha extract is performed.

Ashwagandha extract can be powdered through a concentration process.

In one embodiment, the ashwagandha extract may be powdered through lyophilization after being concentrated under reduced pressure.

In another embodiment, the ashwagandha extract may be concentrated to 20 brix through concentration under reduced pressure, blended by adding dextrin equal to the solid content of the concentrate, and then spray-dried to be powdered.

Thereafter, a composition for improving muscle strength may be prepared by mixing the powdered ashwagandha extract with a food composition or a pharmaceutical composition.

Meanwhile, the present invention is not limited to the above-described method, and the present invention can prepare an ashwagandha extract by preparing an extract from each of the ashwagandha root, leaf, and stem, and mixing each extract in a predetermined ratio.

Through the above method, it is possible to prepare a composition for improving muscle strength in which the content of withaperin A is increased. The composition for improving muscle strength prepared by the above-described manufacturing method has low toxicity and at the same time contains 1.5 times or more of Withaperin A compared to Ashwagandha root extract. Through this, the present invention can provide a composition for improving muscle strength that helps improve muscle strength.

Hereinafter, preferred embodiments are presented to aid understanding of the present invention, but the following examples are merely illustrative of the present invention, and it is obvious to those skilled in the art that various changes and modifications are possible within the scope and spirit of the present invention. It goes without saying that changes and modifications fall within the scope of the appended claims.

Example. Manufacturing method of ashwagandha extract

Dried ashwagandha roots and leaves were mixed at a weight ratio of 14.15: 1, and 40% alcohol 10 times the weight of the raw material mixture was added and immersed for more than 15 hours. After extraction at 50 ° C. for 4 hours, the mixture was filtered with Whatman filter paper. The filtrate was concentrated under reduced pressure and lyophilized to powder.

Thereafter, the contents of Withaperin A, Withanolide A and other index components in the powdered ashwagandha extract were analyzed. A method for analyzing the content of the indicator component will be described later.

The analysis results of the index component of the ashwagandha extract prepared according to the above example are shown in Table 1 below.

Referring to the tables to be described later, in the case of ashwagandha root extract, the content of withaperin A, which helps strengthen muscle strength, does not exceed 2.5 mg/g. On the other hand, referring to Table 1, the ashwagandha extract according to the present invention contains withtaperin A three times more than the ashwagandha root extract. Through Table 1, it can be confirmed that the ashwagandha extract according to the present invention has an increased content of components that help strengthen muscle strength compared to the conventional ashwagandha root extract.

In addition, withanoride A included in the composition according to the present invention is effective in protecting DNA-damage caused by oxidative stress, in inflammatory response by 7-ketocholesterol in vascular endothelial cells, and in neurodegenerative diseases. It may have anti-inflammatory and anticoagulant effects.

Hereinafter, experimental examples in which the efficacy of the ashwagandha extract, the stability of the ashwagandha extract, the preparation of the ashwagandha extract under various conditions, and the analysis of components of the ashwagandha extract will be described.

Experimental Example 1. Evaluation of muscle strength improvement effect of ashwagandha extract

Ashwagandha root extract and ashwagandha leaf extract were prepared in the same manner as described in Examples. Powdered ashwagandha root extract and powdered ashwagandha leaf extract were mixed in a predetermined weight ratio to evaluate the thickness increase of myotubes.

After culturing C2C12 cells, when they reached 80% confluency, they were cultured in 2% horse serum-containing media for 7 days to differentiate into myotubes. Thereafter, the samples were treated in combination with 50 μM dexamethasone, cultured for 48 hours, and the thickness of myotube cells was measured.

To measure the thickness of the root canal cells, the cells were photographed using an optical microscope equipped with a CCD camera and then analyzed using image J software.

The analysis results are shown in Figures 1 and 2.

Referring to Figures 1 and 2, when the ashwagandha root extract and leaf extract were mixed at a ratio of 9:1, the thickness increase of myotube cells was the highest. The ratio of 9: 1 is the same as that extracted after mixing the raw materials of ashwagandha root and ashwagandha leaf at a weight ratio of 14.15: 1.

As shown in Table 2 below, the weight ratio of the raw materials was calculated after calculating the weight of the raw materials necessary for preparing 10 g of the extract based on the extraction yield, and then the weight ratio of the raw materials was calculated.

Through Tables 1 and 2, it can be seen that when the extract is prepared after mixing the ashwagandha root and leaf at a weight ratio of 14.15: 1, the strength enhancing effect is the best.

Experimental Example 2. Cytotoxicity evaluation

Ashwagandha root extract and ashwagandha leaf extract were prepared in the same manner as described in Examples. Powdered ashwagandha root extract and powdered ashwagandha leaf extract were mixed in a predetermined weight ratio and administered to myotube cells, and then toxicity was confirmed.

After culturing C2C12 cells, when they reached 80% confluency, they were cultured in 2% horse serum-containing media for 7 days to differentiate myotubes, and samples were then treated for each concentration. After 48 hours of sample treatment, the MTS reagent was treated in an amount of 20% of the medium and cultured for 2 hours. Subsequently, cell viability was confirmed by measuring absorbance at 490 nm using a microplate reader.

Referring to FIG. 3 , when the ashwagandha root extract and the leaf extract were mixed at a ratio of 9:1, it can be confirmed that myotube cells proliferated significantly. In the case of the extract in which the ashwagandha root extract and the leaf extract were mixed at a ratio of 8:2 and 7:3, it was confirmed that the number of root canal cells decreased and toxicity appeared.

Experimental Example 3. Preparation of Ashwagandha Extract by Ethanol Concentration of Extraction Solvent

An ashwagandha root extract and an ashwagandha leaf extract were prepared in the same manner as described in Examples, but each extract was prepared by varying the ethanol concentration of the extraction solvent.

Here, the ethanol concentration of the aqueous ethanol solution as the extraction solvent was 10%, 20%, 30%, 40%, 50%, and 60%.

Thereafter, the yield of the extract was calculated, and the contents of Withaperin A and Withanoride A in the extract were measured. The yield calculation results and the results of measuring the contents of withaperrin A and withanolide A are shown in FIGS. 4a and 4b.

Figure 4a shows the yield of ashwagandha root extract, the contents of withaperin A and withanolide A according to the ethanol concentration of the extraction solvent, and Figure 4b shows the yield of ashwagandha leaf extract according to the ethanol concentration of the extraction solvent, witha It shows the contents of perrin A and withanolide A.

Referring to Figures 4a and 4b, when the ethanol concentration is 40% or more, it can be seen that there is no significant difference in the extraction yield and the index component content. When the ethanol concentration is more than 50%, since a separate explosion-proof device must be installed, the optimal solvent condition was set to 40% ethanol.

Experimental Example 4. Preparation of Ashwagandha Extract by Extraction Temperature

Ashwagandha root extract and ashwagandha leaf extract were prepared in the same manner as described in Examples, but each extract was prepared by changing the extraction temperature.

Here, the extraction temperature was 40 ℃, 50 ℃, 60 ℃, 70 ℃, 80 ℃.

Thereafter, the yield of the extract was calculated, and the contents of Withaperin A and Withanoride A in the extract were measured. The yield calculation results and the results of measuring the contents of withaperin A and withanolide A are shown in FIGS. 5a and 5b.

Figure 5a shows the yield of ashwagandha root extract, the contents of withaperin A and withanolide A according to the extraction temperature, and Figure 5b shows the yield of ashwagandha leaf extract, withaperin A and withanolide according to the extraction temperature Indicates the content of A.

Referring to Figures 5a and 5b, when the extraction temperature is 50 ℃, it can be seen that the content of withaperin A is the highest.

Experimental Example 5. Preparation of Ashwagandha Extract by Extraction Time

Ashwagandha root extract and ashwagandha leaf extract were prepared in the same manner as described in Examples, but each extract was prepared by changing the extraction time.

Here, the extraction times were 2 hours, 4 hours, 6 hours, 8 hours, and 12 hours.

Thereafter, the yield of the extract was calculated, and the contents of Withaperin A and Withanoride A in the extract were measured. The yield calculation results and the results of measuring the contents of withaperrin A and withanolide A are shown in FIGS. 6a and 6b.

Figure 6a shows the yield of ashwagandha root extract, the contents of withaperin A and withanolide A according to extraction time, and Figure 6b shows the yield of ashwagandha leaf extract, withaperin A and withanolide according to extraction time Indicates the content of A.

6a and 6b, in the case of the ashwagandha root extract, the content of the marker component increases as the extraction time increases, and in the case of the ashwagandha leaf extract, it can be seen that the content of the marker component in the 4-hour extract is the highest. .

Experimental Example 6. Preparation of Ashwagandha Extract for Each Raw Material Grinding Condition

Ashwagandha root extracts were prepared in the same manner as described in Examples, but the raw material grinding conditions were different to prepare each extract.

Here, the pulverization conditions were no pulverization, coarse pulverization, and fine pulverization.

The coarsely pulverized mixture had an average particle diameter of 1 to 10 cm, and the finely pulverized mixture had an average particle diameter of about 1 cm.

Thereafter, the yield of the extract was calculated, and the contents of Withaperin A and Withanoride A in the extract were measured. The yield calculation results and the results of measuring the contents of withaperrin A and withanoride A are shown in FIG. 7 .

Figure 7 shows the yield of ashwagandha root extract, the contents of withapherin A and withanolide A according to grinding conditions.

Referring to FIG. 7 , when considering the extraction yield and withaperin A content of the ashwagandha root extract according to the grinding conditions, it can be confirmed that the index component content is optimized when the raw material is coarsely pulverized.

Experimental Example 7. Preparation of ashwagandha extract with or without immersion

The ashwagandha root extract and the ashwagandha leaf extract were prepared in the same manner as described in Examples, but each extract was prepared by varying the presence or absence of immersion before extraction.

The immersion conditions were immersed for 15 hours after mixing the crudely pulverized raw material and the extraction solution.

Thereafter, the yield of the extract was calculated, and the contents of Withaperin A and Withanoride A in the extract were measured. The yield calculation results and the results of measuring the contents of Withaperrin A and Withanoride A are shown in FIG. 8 .

Figure 8 shows the yield of ashwagandha root and leaf extracts, the contents of withapherin A and withanolide A according to the presence or absence of immersion.

Referring to FIG. 8, it can be confirmed that the yield and index component increase when immersion is performed before extraction.

Experimental Example 8. Comparison of single extract and composite extract of ashwagandha root and leaf

Ashwagandha root extract, ashwagandha leaf extract (hereinafter referred to as single extract), and a mixture of the two extracts (hereinafter referred to as extract mixture) were prepared in the same manner as described in Examples, and the raw material state was prepared by the method described in Examples. Ashwagandha root and leaves were mixed to prepare an Ashwagandha extract (hereinafter referred to as a composite extract).

The mixed weight ratio of the ashwagandha root extract and the ashwagandha leaf extract in the extract mixture was 9:1.

The index component analysis results for the single extract are shown in Table 3 below. Meanwhile, the index component analysis results described in FIGS. 1 to 7 were conducted in terms of screening to find optimal experimental conditions. At this time, as the content of the marker component was analyzed without completely drying the sample, the content of the marker component was calculated to be relatively small. The results of Tables 3 to 5 are the results of analyzing the content of the marker component after completely drying the extract.

The index component analysis results for the composite extract are shown in Table 5 below.

Referring to Tables 4 to 6, even if the ashwagandha root extract and the ashwagandha leaf extract are separately prepared and mixed, or the ashwagandha root and leaf are mixed and prepared, there is no significant difference in the content of withaperin A. Confirmed (error rate -1.7%)

Experimental Example 9. Method for analyzing the content of Withaperin A

High performance liquid chromatography (HPLC) analysis of Withaferin A was analyzed using Shimadzu's LC-20AD and SPD-M20A, and the analysis conditions are shown in Table 6 below. Content analysis of the components listed in Tables 3 to 5 was also performed through the above method.

As described above, according to the present invention, the content of withaperin A can be increased while minimizing the toxicity of the ashwagandha extract. Through this, the present invention can provide a composition for improving muscle strength containing an ashwagandha extract that helps improve muscle strength.

Although the embodiments of the present invention have been described with reference to the accompanying drawings, those skilled in the art to which the present invention pertains can be implemented in other specific forms without changing the technical spirit or essential features of the present invention. you will be able to understand Therefore, it should be understood that the embodiments described above are illustrative in all respects and not restrictive.

Claims (7)

In the food composition for improving muscle strength containing ashwagandha extract,
extract of ashwagandha root; and
Contains ashwagandha leaf extract as an active ingredient,
The weight ratio between the extract of the ashwagandha root and the extract of the ashwagandha leaf is 8.5: 1 to 9.5: 1,
A food composition for improving muscle strength containing 7.2 to 10.8 mg of Withapherin A based on 1 g of the composition. delete delete delete According to claim 1,
The composition for improving muscle strength, characterized in that promotes the increase in the thickness of the root canal cells. delete In the method for producing a food composition for improving muscle strength containing ashwagandha extract,
Preparing a raw material mixture by mixing ashwagandha root and ashwagandha leaf in a weight ratio of 13.4: 1 to 14.9: 1;
Mixing the raw material mixture with a 40 to 50% aqueous ethanol solution and immersing for 15 hours or longer;
Preparing an ashwagandha extract by performing extraction at a temperature of 40 to 60 ° C. for 4 to 6 hours; and
Concentrating and drying the ashwagandha extract to prepare a composition for improving muscle strength,
Method for producing a food composition for improving muscle strength, characterized in that it comprises 7.2 to 10.8 mg of Withapherin A based on 1 g of the composition.

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