KR102522293B1 - Liquid detergent composition for clothing - Google Patents

Abstract

(Problem) A medical liquid detergent composition capable of further increasing detergency and having excellent low foaming and foaming properties.
(Solution) (A) component: anionic surfactant excluding soap, (B) component: fatty acid having 12 carbon atoms or a salt thereof, component (C): fatty acid having 14 to 18 carbon atoms or a salt thereof, (D) Component: Contains a nonionic surfactant, and the mass ratio represented by (A) component / ((A) component + (D) component) is 0.2 or more and less than 0.9, and is represented by (C) component / (B) component The medical liquid detergent composition whose mass ratio is 0.03 or more and 0.5 or less.

Description

Medical liquid detergent composition {LIQUID DETERGENT COMPOSITION FOR CLOTHING}

The present invention relates to a medical liquid detergent composition.

Anionic surfactants with excellent cleaning power and good foaming are widely used as medical cleaning agents. When such an anionic surfactant is used as a main surfactant in a cleaning agent, there is a risk that foam overflows during cleaning in a drum-type washing machine. Therefore, detergents used in drum type washing machines are required to be difficult to foam (low foaming property). In addition, it is desired that foam disappears quickly during rinsing (foaming property), so that rinsing can be completed quickly (good rinsing property).

Patent Literature 1 introduces a liquid detergent composition having low foaming properties and good rinseability at the time of washing by using a nonionic surfactant as a main surfactant and containing a small amount of anionic surfactant.

Japanese Unexamined Patent Publication No. 2002-167600

However, although Patent Document 1 uses a nonionic surfactant as the main surfactant to improve low foaming properties and rinseability during washing, when an anionic surfactant is used as the main surfactant to increase cleaning power, low foaming property is improved. not holding up

Then, this invention aims at the medical liquid detergent composition which can further raise cleaning power, and is excellent in low-foaming property and foaming property.

The present invention has the following aspects.

[1] (A) component: anionic surfactant excluding soap, (B) component: fatty acid having 12 carbon atoms or a salt thereof, component (C): fatty acid having 14 to 18 carbon atoms or a salt thereof, and component (D) : Contains a nonionic surfactant, and the mass ratio represented by (A) component / ((A) component + (D) component) is 0.2 or more and less than 0.9, and the mass ratio represented by (C) component / (B) component A medical liquid detergent composition of 0.03 or more and 0.5 or less.

[2] (E) component: The medical liquid detergent composition as described in [1] which further contains an enzyme.

[3] Component (F): The medical liquid detergent composition according to [1] or [2] further containing a chelating agent.

[4] Component (G): The medical liquid detergent composition according to any one of [1] to [3] further containing an antifoaming auxiliary agent.

[5] The medical liquid detergent composition according to any one of [1] to [4], wherein the total content of component (A) and component (D) is 5 to 60% by mass with respect to the total mass of the liquid medical detergent composition.

[6] The medical liquid detergent composition according to any one of [1] to [5], wherein the mass ratio represented by (A) component/((B) component + (C) component) is 1.5 or more and less than 13.8.

[7] The medical liquid detergent composition according to any one of [1] to [6], in which the mass ratio represented by (D) component/((B) component + (C) component) is 0.8 or more and less than 30.

ADVANTAGE OF THE INVENTION According to this invention, the cleaning power can be further improved, and the medical liquid detergent composition excellent in low foaming property and foaming property can be provided.

[Medical liquid detergent composition]

The medical liquid detergent composition of the present invention (hereinafter sometimes referred to simply as a liquid detergent) contains component (A), component (B), component (C), and component (D).

The liquid detergent of this invention uses an anionic surfactant as a main surfactant. Here, that the anionic surface active agent is the main surfactant means that the mass ratio of the anionic surfactant to the total mass of the anionic surfactant and the nonionic surfactant is 0.2 or more.

<Component (A)>

(A) component is an anionic surfactant excluding soap. A liquid detergent can improve cleaning power by containing (A) component. As an anionic surfactant, the following (1) - (10) are mentioned, for example.

(1) Linear or branched alkylbenzene sulfonic acid salts (LAS or ABS) having an alkyl group of 8 to 18 carbon atoms.

(2) α-sulfofatty acid ester salt (MES).

(3) α-olefin sulfonic acid salts (AOS) having 10 to 20 carbon atoms.

(4) polyoxyethylene monoalkyl, dialkyl or sesquialkyl phosphates.

(5) An average amount of 0.5 to 10 moles of any of the alkylene oxides having 2 to 4 carbon atoms or ethylene oxide (EO) and propylene oxide (PO) (EO/PO molar ratio is 0.1/9.9 to 9.9/0.1) An alkyl (or alkenyl) ether sulfate (AES) having a linear or branched chain alkyl (or alkenyl) group of 10 to 20 carbon atoms.

(6) An average of 3 to 30 moles of either alkylene oxide having 2 to 4 carbon atoms or ethylene oxide and propylene oxide (molar ratio of EO/PO of 0.1/9.9 to 9.9/0.1) having 10 to 20 carbon atoms added. An alkyl (or alkenyl) phenyl ether sulfate having a linear or branched chain alkyl (or alkenyl) group.

(7) An average of 0.5 to 10 moles of any of alkylene oxides having 2 to 4 carbon atoms or ethylene oxide and propylene oxide (EO/PO molar ratio of 0.1/9.9 to 9.9/0.1) having 10 to 20 carbon atoms added. An alkyl (or alkenyl) ether carboxylate having a linear or branched chain alkyl (or alkenyl) group.

(8) Alkyl polyhydric alcohol ether sulfates such as alkyl glyceryl ether sulfonic acids having 10 to 20 carbon atoms.

(9) long chain monoalkyl, dialkyl or sesquialkyl phosphates.

(10) Alkyl sulfate or alkenyl sulfate (AS) having 10 to 20 carbon atoms.

You may use anionic surfactants other than what was illustrated above. For example, carboxylic acid type anionic surfactants such as alkyl ether carboxylates, polyoxyalkylene ether carboxylates, alkylamide ether carboxylates, alkenylamide ether carboxylates, and acylaminocarboxylates; phosphate ester type anionic surfactants such as alkyl phosphate ester salts, polyoxyalkylene alkyl phosphate ester salts, polyoxyalkylene alkylphenyl phosphate ester salts, and glycerin fatty acid ester monophosphate ester salts; and the like.

Examples of the salt form of the anionic surfactant include alkali metal salts such as sodium salt and potassium salt; alkaline earth metal salts such as magnesium salt; alkanolamine salts such as monoethanolamine salts and diethanolamine salts; Ammonium salt etc. are mentioned. Especially, an alkali metal salt is preferable.

(A) component may be used individually by 1 type, and may be used in combination of 2 or more types.

(A) component includes at least one kind of anionic surfactant selected from the group consisting of (1), (2), (3) and (5) above, since it is easy to obtain better detergency among the above. Preferably, a combination of (1), (2), (3) and (5), a combination of (1), (2) and (5), a combination of (1), (3) and (5), and It is more preferable to include at least one type of anionic surfactant selected from the group consisting of combinations of (1) and (5).

1-30 mass % is preferable with respect to the gross mass of a liquid detergent, as for content of (A) component, 2-20 mass % is more preferable, and its 3-15 mass % is still more preferable. (A) When content of component is more than the said lower limit, the liquid detergent excellent in protein cleaning property is easy to be obtained. Moreover, it becomes easy to obtain the liquid detergent excellent in recontamination prevention property. Moreover, a liquid detergent with favorable fluidity|liquidity is easy to be obtained as content of (A) component is below the said upper limit.

Here, "re-contamination prevention property" is a property that prevents stains desorbed from the object to be washed (object to be washed) from adhering to the object to be cleaned again by performing a washing treatment.

One aspect of this invention WHEREIN: (A) component may contain the above-mentioned (2). Further, (2) is preferably an α-sulfofatty acid ester represented by the following formula (a1) (hereinafter referred to as component (a)).

R ³ CH(SO ₃ M)COOR ⁴ . . . (a1)

(In formula (a1), R ³ is a hydrocarbon group having 10 to 16 carbon atoms, R ⁴ is a hydrocarbon group having 1 to 6 carbon atoms, and M is a counter ion.)

(component (a))

In the formula (a1), the hydrocarbon group of R ³ has 10 to 16 carbon atoms. That is, carbon number of the fatty acid residue which component (a) has is 12-18. Fatty acid moiety refers to an acyl moiety. When the carbon number of R ³ is 10 or more, the surface activity is strong and the detergency becomes better. It is excellent in low-temperature stability of a liquid detergent as carbon number of R ^<3> is 16 or less.

The hydrocarbon group for R ³ may be linear or branched, or may have a cyclic structure. The hydrocarbon group for R ³ is preferably an aliphatic hydrocarbon group, more preferably a linear or branched alkyl group or a linear or branched alkenyl group, and still more preferably a linear or branched chain alkenyl group.

In formula (a1), R ⁴ has 1 to 6 carbon atoms, preferably 1 to 3.

The hydrocarbon group for R ⁴ may be linear or branched, or may have a cyclic structure. The hydrocarbon group for R ⁴ is preferably an aliphatic hydrocarbon group, more preferably a linear or branched alkyl group or a linear or branched alkenyl group, and still more preferably a linear or branched chain alkyl group.

As R ⁴ , since detergency is further improved, a methyl group, an ethyl group, an n-propyl group, an isopropyl group, and the like are preferable, a methyl group, an ethyl group, and an n-propyl group are preferable, and a methyl group is particularly preferable.

In formula (a1), M is preferably one that can form a water-soluble salt together with R ³ CH(COOR ⁴ )SO ₃ ^- , and examples thereof include alkali metal ions, protonated amines, and ammonium ions. there is. Sodium etc. are mentioned as an alkali metal which can become said M. Primary to tertiary amines etc. are mentioned as said amine which can become M. It is preferable that the total carbon number of the said amine is 1-6. Moreover, the said amine may have a hydroxyl group. Since the solubility with respect to water of (a) component becomes high, it is preferable that the said amine has a hydroxyl group. Examples of the amine having a hydroxyl group include alkanolamines, and the alkanol group preferably has 1 to 3 carbon atoms. Examples of alkanolamines include monoethanolamine, diethanolamine, and triethanolamine.

As said M, an alkali metal ion is preferable and a sodium ion is especially preferable from the point which it is easy to obtain and the low-temperature stability of a liquid detergent becomes easy to become higher.

As the component (a), R ³ in the formula (a1) is a C 14-C 16 linear or branched alkyl group or a C 14-C 16 linear or branched alkenyl group, and R ⁴ is a methyl group. compounds are particularly preferred.

Any of (a) component may be used individually by 1 type, and 2 or more types may be combined together and they may be used.

It is preferable that it is a mixture which mixed the compound with which carbon number of a fatty acid residue differs from the solubility to water becoming high while washing|cleaning power becomes high as a component (a). In particular, a mixture of a compound (a-1) in which R ³ in the formula (a1) is a hydrocarbon group having 14 carbon atoms and a compound (a-2) in which R ³ in the formula (a1) is a hydrocarbon group having 16 carbon atoms this is preferable In such a mixture, the mass ratio of compound (a-1) to compound (a-2) is preferably (a-1):(a-2) = 45:55 to 95:5, 60:40 to 90: 10 is more preferable, and 80:20 to 85:15 are still more preferable. When this mass ratio is within the above preferred range, the detergency, the solubility in water, and the low-temperature stability of the liquid detergent tend to become better.

Component (a) is an α-sulfofatty acid ester obtained by a known production method, for example, by using a tank-type reactor with an agitator according to the conventional method, and contacting the raw material fatty acid ester with sulfuric anhydride to sulfonate it. A product obtained by preparing (α-SF acid) and then neutralizing the α-SF acid with sodium hydroxide or the like may be used, or a commercially available product may be used. Moreover, what bleached with hydrogen peroxide etc. before and after neutralization may be used.

0-6.0 mass % is preferable with respect to the gross mass of a liquid detergent, as for content of (a) component, 0.5-4.0 mass % is more preferable, and its 1.0-3.0 mass % is still more preferable. When the content of the component (a) is within the above range, it is easy to obtain a liquid detergent having excellent detergency, anti-recontamination, dispersion stability, and enzyme stability. In addition, it becomes easy to maintain the degree of freedom in the formulation of other components.

The ratio of (a) component in (A) component (hereinafter sometimes referred to as (a)/(A) ratio) is preferably 0/100 or more and 50/100 or less, and 5/100 or more and 40/100 or more. 100 or less is more preferable, and 10/100 or more and 30/100 or less are still more preferable.

(soap)

Soap is a higher fatty acid salt represented by the following formula (a2).

R ⁵ -COOX . . . (a2)

However, in Formula (a2), R ⁵ is a C7-C17 linear or branched alkyl group or a linear or branched alkenyl group. X in Formula (a2) is an alkali metal salt, an amine salt, an ammonium salt, an alkanolamine salt, etc.

In the present invention, components (B) and (C) described later may correspond to formula (a2), and in this case, soap corresponds to component (B) or component (C). Therefore, soap is excluded from (A) component.

<Component (B)>

Component (B) is a fatty acid having 12 carbon atoms or a salt thereof (hereinafter, simply referred to as a fatty acid (salt)). As the component (B), at least one selected from fatty acids represented by the following general formula (I) and their alkali metal salts, amine salts, ammonium salts, alkanolamine salts, and the like is exemplified. A liquid detergent can improve low-foaming property by containing (B) component.

R ⁶ -COOM . . . (I)

(However, in formula (I), R ⁶ is a saturated hydrocarbon group or an unsaturated hydrocarbon group having 11 carbon atoms. R ⁶ may be linear or branched or may include a cyclic structure. M is hydrogen; alkali metals, amines, ammonia, alkanolamines, etc.)

As (B), since low foaming property and miscibility with detergent increase, R ⁶ is preferably a straight-chain saturated hydrocarbon group, and M is preferably a hydrogen atom, an alkali metal, or an alkanolamine.

(B) component may be used individually by any 1 type, and may be used in combination of 2 or more types.

<Component (C)>

(C) component is a C14-C18 fatty acid (salt). (C) As a component, at least 1 sort(s) chosen from the fatty acid represented by the following general formula (II), its alkali metal salt, amine salt, ammonium salt, alkanolamine salt, etc. is mentioned. A liquid detergent can improve foamability by containing (C)component.

R ⁷ -COOM... (II)

(However, in formula (II), R ⁷ is a saturated or unsaturated hydrocarbon group having 13 to 17 carbon atoms. It is preferable that R ⁷ has 15 to 17 carbon atoms. M is hydrogen, an alkali metal, an amine, ammonia, or an alkane. olamine, etc.)

By combining (B) component and (C) component, cell breakability can be further improved.

(C) component may be used individually by any 1 type, and may be used in combination of 2 or more types. When combining 2 or more types, it is preferable to use together the C15 fatty acid (salt) of R ^<7> and the C17 fatty acid (salt) of R ^<7> . By combining 2 or more types, external appearance stability becomes favorable.

Among liquid detergents, the mass ratio represented by (A) component / ((B) component + (C) component) (hereinafter sometimes referred to as (A) / (B + C) ratio) is, for example, 1.5 or more It is preferably less than 13.8, more preferably 2 or more and less than 13, and still more preferably 3 or more and less than 9. If it is within the above range, the cell-opening properties can be further improved, and the external appearance stability can be further improved.

Among liquid detergents, the mass ratio (hereinafter sometimes referred to as (D)/(B+C) ratio) represented by (D) component/((B) component + (C) component) is, for example, 0.8 or more It is preferably less than 30, more preferably 1 or more and less than 20, and still more preferably 1.5 or more and less than 9. If it is within the above range, the cell-opening properties can be further improved, and the external appearance stability can be further improved.

By combining a higher fatty acid (salt) in which R ⁶ has 11 carbon atoms and a higher fatty acid (salt) in which R ⁷ has 13 to 17 carbon atoms, low foaming properties and breakability can be further improved.

In the liquid detergent, the mass ratio represented by (C) component/(B) component (hereinafter sometimes referred to as (C)/(B) ratio) is 0.03 or more and 0.5 or less, preferably 0.05 or more and 0.38 or less, and 0.06 More than 0.3 or less is more preferable. When the (C)/(B) ratio is within the above range, the cell openability and external appearance stability can be further improved.

(C) The reason why the low foaming property, openability and external appearance stability can be further improved by setting the / (B) ratio within the above range is not clear, but it is considered as follows. That is, the number of composite particles produced by the reaction between polyvalent metal ions and fatty acids in tap water increases, and the particle shape and surface hydrophobicity change, making it suitable for breaking the foam film.

In the liquid detergent, the sum of the contents of component (B) and component (C) is preferably 0.1% by mass or more and less than 2% by mass, more preferably 0.5% by mass or more and less than 1.8% by mass with respect to the total mass of the liquid detergent, 1.1 mass % or more and less than 1.7 mass % are more preferable.

It becomes easy to obtain the liquid detergent excellent in low foamability and foaming property as the sum total of content of (B)component and (C)component is more than the said lower limit. It becomes easy to maintain a transparent uniform liquid appearance as the sum total of content of (B)component and (C)component is below the said upper limit.

<Component (D)>

(D) component is a nonionic surfactant. The liquid detergent of this invention is more excellent in external appearance stability, breakability, and sebum cleansing property by containing (D)component as surfactant other than (A)component.

(D) The content of the component is preferably 0.5% by mass or more and 30% by mass or less, more preferably 1% by mass or more and 20% by mass or less, and still more preferably 2% by mass or more and 10% by mass or less with respect to the total mass of the liquid detergent. do.

The total content of component (A) and component (D) is preferably 80% by mass or more and 100% by mass or less, and 85% by mass or more and 100% by mass or less with respect to the total mass of the surfactant (excluding soap). More preferably, 90 mass % or more and 100 mass % or less are still more preferable, and 100 mass % may be sufficient.

In addition, the mass ratio represented by (A) component/((A) component + (D) component) (hereinafter sometimes referred to as (A)/(A+D) ratio) is 0.2 or more and less than 0.9, and is 0.3 or more 0.8 or less is preferable, and 0.4 or more and 0.7 or less are more preferable. When the (A)/(A+D) ratio is equal to or greater than the lower limit above, deterioration in protein detergency and anti-recontamination properties is easily suppressed. Among surfactants, those that mainly contribute to cleaning power are anionic surfactants and nonionic surfactants. (A)/(A+D) ratio represents the content ratio of the anionic surfactant to the surfactant contributing to detergency.

(D) As a component, the following (1)-(5) is mentioned, for example.

(1) An average of 3 to 30 moles, preferably 3 to 20 moles, more preferably 5 to 20 carbon atoms of an alkylene oxide having 2 to 4 carbon atoms in a monohydric aliphatic alcohol having 6 to 22 carbon atoms, preferably 8 to 18 carbon atoms. Polyoxyalkylenealkyl (or alkenyl) ether added by mole. Among these, polyoxyethylene alkyl (or alkenyl) ether and polyoxyethylene polyoxypropylene alkyl (or alkenyl) ether are preferable. Primary alcohol and secondary alcohol are mentioned as monohydric aliphatic alcohol used here. Moreover, the alkyl group may have a branched chain. As the aliphatic alcohol, a primary alcohol is preferable.

(2) polyoxyethylene alkyl (or alkenyl) phenyl ether.

(3) Fatty acid alkyl ester alkoxylates in which alkylene oxide is added between ester bonds of long-chain fatty acid alkyl esters.

(4) polyoxyethylene fatty acid esters.

(5) Polyoxyethylene hydrogenated castor oil.

As a nonionic surfactant, the thing of said (1) or (3) is preferable, and among these, what is represented by the following general formula (III) or (IV) is preferable.

R ⁸ -C(=O)O-[(EO) _s /(PO) _t ]-(EO) _u -R ⁹ . (III)

R ¹⁰ -O-[(EO) _v / (PO) _w ]-(EO) _x -H . (IV)

(In formula (III), R ⁸ is a hydrocarbon group having 7 to 22 carbon atoms, R ⁹ is an alkyl group having 1 to 6 carbon atoms, s represents the average repeating number of EO, is a number of 6 to 20, and t is PO represents the average repeating number of 0 to 6, u represents the average repeating number of EO, represents a number of 0 to 20, EO represents an oxyethylene group, and PO represents an oxypropylene group.

In formula (IV), R ¹⁰ is a hydrocarbon having 6 to 22 carbon atoms, v represents the average repeating number of EO and is a number of 3 to 20, w represents the average repeating number of PO and is a number of 0 to 6; , x represents the average repeating number of EO, and is a number from 0 to 20, EO represents an oxyethylene group, and PO represents an oxypropylene group.)

In Formula (III), R ⁸ is a hydrocarbon group having 7 to 22 carbon atoms. 9-21 are preferable and, as for carbon number of R ^<8> , 11-21 are more preferable.

R ⁸ is an alkyl group or preferably an alkenyl group.

R ⁸ may be linear or branched.

From the viewpoint of further improvement in detergency, R ⁸ is preferably a linear or branched alkyl group having 7 to 22 carbon atoms or a linear or branched alkenyl group having 7 to 22 carbon atoms.

R ⁹ is an alkyl group having 1 to 6 carbon atoms, and may be straight-chain or branched. Among them, a methyl group and an ethyl group are preferable.

In Formula (III), s and u are numbers each independently representing the average repetition number of EO.

s+u is preferably 6 to 20, more preferably 6 to 18, and still more preferably 11 to 18. It becomes easy to improve liquid stability more as it is more than the said lower limit. It becomes easy to improve cleaning power more that it is below the said upper limit.

In formula (III), t is a number representing the average repeating number of PO.

t is a number of 0 to 6, preferably 0 to 3. It becomes easy to improve liquid stability more as it is below the said upper limit.

When t is 1 or more, in [(EO) _s / (PO) _t ], the oxyethylene group and the oxypropylene group may be bonded in a random shape or may be bonded in a block shape.

In this specification, the average number of repetitions can be measured by gas chromatography or the like.

In Formula (IV), R ¹⁰ is a hydrocarbon group having 6 to 22 carbon atoms.

In the formula (IV), the number of carbon atoms in R ¹⁰ is preferably 10 to 22, more preferably 10 to 20, still more preferably 10 to 18, from the viewpoint of further improving detergency.

R ¹⁰ may be linear or branched.

Preferred examples of R ¹⁰ -O- include groups represented by the following general formula (V).

(R ¹⁰¹ )(R ¹⁰² )CH-O- . . . (V)

(In formula (V), R ¹⁰¹ and R ¹⁰² each independently represent a hydrogen atom or a chain hydrocarbon group, and the total number of carbon atoms of R ¹⁰¹ and R ¹⁰² is 5 to 21.)

The total number of carbon atoms of R ¹⁰¹ and R ¹⁰² is preferably 9 to 21, more preferably 9 to 19, still more preferably 9 to 17.

R ¹⁰¹ and R ¹⁰² may be linear or branched.

As R ¹⁰ , an alkyl group having 12 to 14 carbon atoms is preferable, and an alkyl group in which the carbon bonded to the oxygen atom is secondary carbon is preferable.

In Formula (IV), v and x are numbers each independently representing the average repetition number of EO.

v+x is preferably 3 to 20, more preferably 5 to 18, still more preferably 6 to 18, particularly preferably 7 to 18, and most preferably 12 to 15. If it is more than the said lower limit, it will become easy to improve cell-opening property and external appearance stability. It becomes easy to improve cleaning power more that it is below the said upper limit.

In Formula (IV), w is a number representing the average repeating number of PO.

w is a number of 0 to 6, preferably 0 to 3. It becomes easy to improve liquid stability more as it is below the said upper limit.

When w is 1 or more, in [(EO) _v /(PO) _w ], the oxyethylene group and the oxypropylene group may be bonded in a random shape or may be bonded in a block shape.

The distribution of EO or PO in formula (III) varies depending on the reaction method at the time of production. For example, when ethylene oxide or propylene oxide is added to the raw material using sodium hydroxide or potassium hydroxide, which are common alkali catalysts, the distribution of v or w becomes relatively wide. Oxidation with addition of metal ions such as Al ³⁺ , Ga ³⁺ , In ³⁺ , Tl ³⁺ , Co ³⁺ , Sc ³⁺ , La ³⁺ , Mn ²⁺ described in Japanese Patent Publication No. 6-15038 When ethylene oxide or propylene oxide is added to the raw material using a specific alkoxylation catalyst such as magnesium, the distribution of v or w becomes relatively narrow.

The nonionic surfactant represented by formula (III) (hereinafter also referred to as component (d11)) and the nonionic surfactant represented by formula (IV) (hereinafter also referred to as component (d12)) have a narrow rate ( narrow ratio) is preferably 20% by mass or more, and more preferably 25% by mass or more. The higher the narrow ratio, the better the cleaning power. Moreover, when the said narrow rate is 20 mass % or more, especially 25 mass % or more, it becomes easy to obtain the detergent composition with few raw material odors of surfactant.

When component (d11) is produced by the usual method, in the product, together with component (d11), components that do not contribute to cleaning power, for example, fatty acid esters that are raw materials for component (d11), and nonions represented by formula (III) An ethylene oxide adduct in which s of the surfactant is 1 or 2 coexists and lowers the narrow rate. Therefore, when the narrow rate is high, the coexisting components are sufficiently small, and the problems of deterioration of detergency and odor of raw materials are less likely to occur. The case of component (d12) is also the same.

Although it does not specifically limit as an upper limit of the said narrow rate, It is preferable that it is 80 mass % or less substantially.

As said narrow rate, since liquid stability and solubility improve, it is more preferable that it is 20-50 mass %, and 20-40 mass % is still more preferable.

Here, in this specification, "narrow ratio" shows the ratio of the distribution of ethylene oxide adducts with different added mole numbers of EO, and is represented by the following formula (S).

[In formula, p _max represents the added mole number of EO of the ethylene oxide adduct which exists most in all ethylene oxide adducts. i represents the added mole number of EO. Yi represents the ratio (mass %) of the ethylene oxide adduct having an added mole number i of EO present in the total ethylene oxide adduct.]

The said narrow rate is controllable by the manufacturing method of a component (d11) or a component (d12), etc., for example. The method for producing component (d11) is not particularly limited, but, for example, a method of addition polymerization of ethylene oxide to a fatty acid alkyl ester using a surface-modified composite metal oxide catalyst (see Japanese Patent Laid-Open No. 2000-144179) can be easily manufactured by As a method for producing component (d12), it can be produced by, for example, a method of addition polymerization of ethylene oxide to an alcohol having 6 to 22 carbon atoms using a surface-modified composite metal oxide catalyst.

Preferred examples of the surface-modified composite metal oxide catalyst used in this method include metal ions (Al ³⁺ , Ga ³⁺ , In ³⁺ , Tl ³⁺ , Co ³⁺ , Sc ³⁺ , La ³⁺ , Mn ^{2+ ,} etc.) may be added to a complex metal oxide catalyst such as magnesium oxide or a calcined product catalyst of hydrotalcite surface-modified with a metal hydroxide and/or a metal alkoxide.

In the surface modification using the composite metal oxide catalyst, it is preferable to use the composite metal oxide in combination with a metal hydroxide and/or a metal alkoxide. In this case, the ratio of the metal hydroxide and/or the metal alkoxide is preferably 0.5 to 10 parts by mass, more preferably 1 to 5 parts by mass, with respect to 100 parts by mass of the composite metal oxide.

As another method for producing the component (d11), there is a method in which alkylene oxide is added to a fatty acid alkyl ester using an alkoxylation catalyst prepared from a mixture of an alkaline earth metal compound and an oxyacid. The alkoxylation catalyst is disclosed in Japanese Patent No. 04977609, WO1993004030, WO2002038269, WO2012028435, etc. For example, an alkaline earth metal salt of carboxylic acid and/or an alkaline earth metal salt of hydroxycarboxylic acid The alkoxylation catalyst prepared from mixtures, such as a metal salt and sulfuric acid, etc. are mentioned.

As a nonionic surfactant, a commercial item may be used, and what was manufactured by the well-known synthetic method may be used. As a known production method, component (d11) can be produced by, for example, a method of addition polymerization of ethylene oxide and/or propylene oxide to fatty acid alkyl esters. Component (d12) can be manufactured by, for example, a method of addition polymerization of ethylene oxide and/or propylene oxide to alcohol having 6 to 22 carbon atoms.

(D)component may be used individually by 1 type, and may be used in combination of 2 or more types.

The content of the surfactant (but excluding soap) relative to the total mass of the liquid detergent is, for example, preferably 5 to 60% by mass, more preferably 5 to 50% by mass, and still more preferably 10 to 40% by mass. desirable.

The mass ratio (hereinafter sometimes referred to as (A)/(B+C) ratio) represented by (A) component/((B) component + (C) component) is 1.5 or more and less than 13.8, and is 2 or more and 13 or less. is preferable, and 3 or more and 9 or less are more preferable. When the (A)/(B+C) ratio is equal to or greater than the lower limit above, deterioration in protein detergency and anti-recontamination properties is easily suppressed.

(D) The mass ratio represented by component/((B) component + (C) component) (hereinafter sometimes referred to as (D)/(B+C) ratio) is 0.8 or more and less than 30, and is 1 or more and 20 or less. is preferable, and 1.5 or more and 9 or less are more preferable. When the (D)/(B+C) ratio is equal to or greater than the lower limit above, deterioration in protein detergency and anti-recontamination properties is easily suppressed.

<Component (E)>

(E) component is an enzyme. The liquid detergent of this invention can further improve cleaning power by containing (E)component.

As the component (E), enzymes used for medical detergent applications and the like can be used, and examples thereof include proteases, amylases, lipases, cellulases, mannanases, and mixtures thereof.

As the protease, commercial names Savinase 16L, Savinase Ultra 16L, Savinase Ultra 16XL, Savinase Evity 16L, Everlase 16L TypeEX, Everlase Ultra 16L, Coronase 48L, Esperase 8L, Alcalase 2.5L, Alcalase Ultra 2.5L available from Novozymes as protease preparations. , Liquanase 2.5L, Liquanase Ultra 2.5L, Liquanase Ultra 2.5XL; Trade names Purafect L, Purafect OX, Properase L, etc. available from Genencore Co., Ltd. are mentioned.

Examples of the amyl agent include Termamyl 300L, Termamyl Ultra 300L, Duramyl 300L, Stainzyme 12L, Stainzyme Plus 12L, and Amplify 12L available from Novozymes as an amylase preparation; Maxamyl available from Genencore Co., Ltd., Fluranase Amano available from Amano Enzyme Co., Ltd. under the trade name; and DB-250 under the trade name available from Seikagaku Kogyo Co., Ltd.

Examples of the lipase include Lipex 100L, Lipex Evity 100L, Lipolase 100L, and the like, available from Novozymes as a lipase preparation.

Examples of the cellulase include Endolase 5000L, Celluzyme 0.4L, Carezyme 4500L and the like available from Novozymes as a cellulase preparation.

As mannanase, Mannaway 4L, a trade name available from Novozymes as a mannanase preparation, and the like are exemplified.

Examples of such mixtures include Medley Core 200L, a trade name available from Novozyme as an enzyme mixture preparation.

(E) component may be used individually by any 1 type, and may be used in combination of 2 or more types.

(E) 0.01-1.0 mass % is preferable with respect to the gross mass of a liquid detergent, as for content of a component, 0.03-0.8 mass % is more preferable, and its 0.05-0.5 mass % is still more preferable. If the content of component (E) is more than the lower limit above, the cleaning effect of protein contamination by component (E) is obtained satisfactorily, and if it is less than the upper limit above, the complex of calcium as a stabilizer in the enzyme preparation, component (B) and component (C) The precipitation of is suppressed, and external appearance stability can be further improved. Moreover, sufficient compounding effect of (E) component is acquired suppressing cost increase. In addition, generation of base material odor is also suppressed satisfactorily.

<Component (F)>

(F) component is a chelating agent. The cleaning power of the liquid detergent of this invention further increases by containing (F)component.

(F) component is at least one compound selected from the group consisting of aminocarboxylic acids, salts of aminocarboxylic acids, hydroxycarboxylic acids, and salts of hydroxycarboxylic acids having a weight average molecular weight of less than 550; am.

Aminocarboxylic acid means a compound having a nitrogen atom and a carboxyl group in one molecule.

A hydroxycarboxylic acid means what does not correspond to an aminocarboxylic acid among the compounds which have a carboxyl group and an alcoholic hydroxyl group in 1 molecule.

(F) The weight average molecular weight of component is less than 550, 400 or less are preferable, 50 or more are preferable, and 100 or more are more preferable.

Component (F) is thought to capture polyvalent metal ions mainly contained in tap water or contamination, and has an action to capture polyvalent metal ions when dissolved in water.

As component (F), an aminocarboxylic acid-based chelating agent and a hydroxycarboxylic acid-based chelating agent are preferable.

An aminocarboxylic acid-based chelating agent means a chelating agent having a nitrogen atom and a carboxyl group in one molecule.

The hydroxycarboxylic acid-based chelating agent means that among chelating agents having a carboxyl group and an alcoholic hydroxy group in one molecule, it does not correspond to an aminocarboxylic acid-based chelating agent.

As the aminocarboxylic acid chelating agent, nitrilotriacetic acid or a salt thereof, ethylenediaminetetraacetic acid or a salt thereof, diethylenetriaminepentaacetic acid or a salt thereof, β-alaninediacetic acid or a salt thereof, aspartic acid diacetic acid or a salt thereof, methyl aminocarboxylic acids or salts thereof, such as glycine diacetic acid or a salt thereof, iminodisuccinic acid or a salt thereof, and ethylenediamine disuccinic acid or a salt thereof; and hydroxyaminocarboxylic acids or salts thereof such as serine diacetic acid or a salt thereof, hydroxyiminodisuccinic acid or a salt thereof, hydroxyethylethylenediamine triacetic acid or a salt thereof, and dihydroxyethylglycine or a salt thereof. .

Examples of the hydroxycarboxylic acid-based chelating agent include lactic acid or a salt thereof, malic acid or a salt thereof, citric acid or a salt thereof, tartaric acid or a salt thereof, glycol or a salt thereof, and gluconic acid or a salt thereof.

Among them, citric acid or a salt thereof, malic acid or a salt thereof, and gluconic acid or a salt thereof are preferable from the viewpoint of the high solubility of the complex with a polyvalent metal ion in water.

As a salt constituting component (F), alkali metal salts such as sodium salt and potassium salt; alkaline earth metal salts such as magnesium salt and calcium salt; alkanolamine salts such as monoethanolamine salts (monoethanolammonium), diethanolamine salts (diethanolammonium), and triethanolamine salts (triethanolammonium); Ammonium salt etc. are mentioned.

(F) component may be used individually by any 1 type, and may be used in combination of 2 or more types.

(F) The content of the component is preferably 0.03% by mass or more and 3.0% by mass or less, more preferably 0.05% by mass or more and 1.0% by mass or less, and 0.08% by mass or more and 0.5% by mass or less with respect to the total mass of the liquid detergent. more preferable

When the content of the component (F) is equal to or less than the lower limit, it is easy to obtain a detergent composition having a uniform and transparent liquid appearance, and to improve the cleaning power.

When the content of the component (F) is equal to or less than the above upper limit, detergency suitable for the blending cost is easily obtained, and the stability of the component (E) tends to be good.

<(G) component>

(G) component is an antifoam adjuvant. The liquid detergent of this invention further contains (G) component, and the defoaming effect becomes higher.

(G) As component, fatty acid 2-ethylhexyl (Pastel 2H-08, trade name), polyoxypropylene glyceryl ether (Aktcol T-3000, trade name), polyoxypropylene glyceryl ether (Aktcol T-4000, trade name) , polyoxypropylene glyceryl ether (Aktcol T-5000, trade name), and at least one selected from silicone formulations.

(G) component may be used individually by 1 type, and may be used in combination of 2 or more types.

(G) As for content of a component, 0.01-20 mass % is preferable with respect to the gross mass of a liquid detergent.

<Optional ingredients>

The liquid detergent of this invention may contain other components normally used for detergents other than the said (A) - (G) component, within the range which does not impede the effect of this invention.

Examples of other components include water, water-miscible organic solvents, thickeners, viscosity reducers, solubilizers, alkali agents such as monoethanolamine, antioxidants, preservatives, calcium chloride, enzyme stabilizers such as sodium lactate, texture improvers, storage stability Enhancers, fluorescent agents, anti-color transfer agents, anti-recontamination agents, pearl agents, soil release agents, flavoring agents, coloring agents, emulsifiers, extracts such as natural products, pH adjusters, and touch improvers.

10-95 mass % is preferable, for example, as for content of the water with respect to the gross mass of a liquid detergent, 20-90 mass % is more preferable, and its 40-90 mass % is still more preferable.

Examples of the water-miscible organic solvent include alcohols such as ethanol, 1-propanol, 2-propanol, 1-butanol, and 3-methoxy-3-methyl-1-butanol (Solpit, trade name); glycols such as propylene glycol (PG), butylene glycol, and hexylene glycol; polyglycols such as diethylene glycol, triethylene glycol, tetraethylene glycol, polyethylene glycol having a weight average molecular weight of about 200 to 1000, and dipropylene glycol; Alkyl ethers, such as diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol monobutyl ether (butyl carbitol), and diethylene glycol dimethyl ether, etc. are mentioned.

Among these, ethanol, 3-methoxy-3-methyl-1-butanol, propylene glycol, polyethylene glycol with a weight average molecular weight of about 200 to 1000, and Ethylene glycol monobutyl ether (butylcarbitol) is preferred.

The water-miscible organic solvent may be used alone or in combination of two or more.

When the liquid detergent of this invention contains a water-miscible organic solvent, 0.1-10 mass % is preferable with respect to the total mass of a liquid detergent, and, as for content of a water-miscible organic solvent, 0.1-5 mass % is more preferable.

In the present invention, the water-miscible organic solvent refers to an organic solvent that dissolves 50 g or more in 1 L of ion-exchanged water at 25°C.

As an antioxidant, 0.01-2 mass % of butylhydroxytoluene, distyrenated cresol, sodium sulfite, sodium hydrogen sulfite, etc. can be included with respect to the total mass of a liquid detergent, for example. Antioxidants may be used individually by 1 type, and may be used in combination of 2 or more types.

Preservatives include 2-bromo-2-nitropropane-1,3-diol, 3-iodopropynylbutyl carbamate, zinc pyrithione, sodium pyrithione, octylisothiazolin-3-one, 1,2- Benzoisothiazolin-3-one (BIT), 5-chloro-2-methylisothiazolin-3-one (CMIT), 2-methylisothiazolin-3-one (MIT), octanediol, benzyl alcohol, Phenoxyethanol, sodium benzoate, etc. are mentioned.

As coloring agents, Atseed Red 138, Polar Red RLS, Liquitint PINK AL, Atseed Yellow 203, Liquitint Bright Yellow, Atseed Blue 9, Blue No. 1, Blue No. 205, Green No. 3, Turquoise P-GR, Liquitint BLUE SE , Levanyl Violet, Red 106 (all are trade names), and the like general-purpose colorants and pigments. Any 1 type of coloring agent may be used independently, and 2 or more types may be combined together and they may be used.

As for the content, when the liquid detergent of this invention contains a coloring agent, 0.00005-0.005 mass % is preferable with respect to the gross mass of a liquid detergent.

Examples of the emulsifying agent include polystyrene emulsion and polyvinyl acetate emulsion, and usually, an emulsion having a solid content of 30 to 50% by mass is suitably used. Specific examples include polystyrene emulsion (trade name: Cybinol (registered trademark) RPX-196 PE-3, solid content: 40% by mass, manufactured by Saiden Chemical Co., Ltd.), Opulyn 301, and Acusol OP 301. Any 1 type of an emulsification agent may be used independently, and 2 or more types may be combined together and may be used.

As for the content, when the liquid detergent of this invention contains an emulsifying agent, 0.001-0.5 mass % is preferable with respect to the gross mass of a liquid detergent.

In addition, the sum total of content of all the components contained in a liquid detergent shall be 100 mass %.

(pH)

As for pH in 30 degreeC of a liquid detergent, 7-10 are preferable from a viewpoint that a cleaning power becomes higher. In particular, when a liquid detergent contains (E)component, it can suppress that the activity of an enzyme falls as pH is in the said range.

The pH of the cleaning agent may be adjusted using an alkanolamine such as monoethanolamine, diethanolamine, or triethanolamine, or a pH adjuster such as sodium hydroxide, potassium hydroxide, or sodium carbonate.

(viscosity)

As for the viscosity in 25 degreeC of the liquid detergent of this invention, 1-2500 mPa*s are preferable. It becomes easy to measure a liquid detergent with a measuring cup etc. as the viscosity of a liquid detergent is in the said range. In addition, it becomes easier to apply the liquid detergent to the object to be cleaned when cleaning by directly applying the liquid detergent to the object to be cleaned. In addition, there is a tendency that a sense of quality is also easily obtained.

The viscosity in 25 degreeC of the liquid detergent in this specification adjusts a sample to 25 degreeC, and shows the value measured using a B-type viscometer. Measurement conditions measure the viscosity after rotation for 30 seconds at a rotation speed of 30 rpm.

The liquid detergent of this invention dissolves (E) component, (F) component, (G) component, and arbitrary components as needed with said (A) component - (D) component, for example in water, pH It is prepared by adjusting to a desired pH with an adjusting agent.

The liquid detergent of this invention can be accommodated in the container used generally. Such a container includes, for example, a nozzle-type container or a stopper-type container with a measuring cup, a squeeze container or a pump container with an automatic metering mechanism or a simple metering mechanism, a trigger container or squeeze for spraying or foaming liquid. A container, an application container having an application surface for applying the liquid, a refill container (pouch, thin bottle, replacement bottle, etc.) and the like are exemplified.

Since the liquid detergent of this invention demonstrated above contains the (A) component, (B) component, (C) component, and (D) component of a specific amount, it is excellent in foaming property and foaming property. In particular, when the liquid detergent contains (E) component, (F) component, and (G) component, while cleaning power is further increased, it is also excellent in enzyme stability.

The liquid detergent of the present invention can be used for any of household, commercial, and industrial uses. Among them, it can be suitably used for household use, and is particularly suitable as a liquid detergent for medical use.

The types of objects to be cleaned include those that are subject to washing in laundry at home, and examples thereof include textile products such as clothes, dishcloths, towels, sheets, and curtains.

The method of using the medical liquid detergent includes, for example, a method of putting the liquid detergent into water together with the object to be cleaned during washing, a method of immersing the object to be cleaned in an aqueous detergent solution prepared by dissolving the liquid detergent in water in advance, and the like. can be heard Alternatively, a liquid detergent may be directly applied to the object to be cleaned, left for a certain period of time, and thereafter, normal washing may be performed (application washing).

(Example)

Hereinafter, the present invention will be described in detail by showing examples, but the present invention is not limited by the following description.

The raw materials and measurement/evaluation methods used in each Example and Comparative Example are as follows.

[Ingredients used]

<Component (A)>

AES-EO2: polyoxyethylene alkyl ether sulfate, manufactured by Kao Co., Ltd., trade name: "EMAL270N", average added mole number of ethylene oxide: 2.

LAS-H: Straight-chain alkyl (C10-C14) benzenesulfonic acid sodium (trade name: "Lifon LH-200" by Lion Specialty Chemicals Co., Ltd.).

MES-Na: Sodium salt of α-sulfofatty acid ester (α-sulfofatty acid ester salt (C16) in which R ³ is an alkyl group having 14 carbon atoms in the formula (a1), and R ³ in the formula (a1) is a carbon number 16 A mixture of α-sulfofatty acid ester salts (C18) that are alkyl groups (mixed mass ratio C16/C18=8/2) (manufactured by Lion Eco Chemicals Sdn. Bhd., trade name: MIZULAN (registered trademark) FL-80).

<Component (B)>

Lauric acid: manufactured by Wako Junyaku High School, trade name: "Lauric acid".

<Component (C)>

Myristic acid: manufactured by Wako Junyaku High School, trade name: "Myristic acid".

Palmitic acid: manufactured by Wako Pure Chemical Industries, Ltd., trade name: "palmitic acid".

Stearic acid: manufactured by Wako Pure Chemical Industries, Ltd., trade name: "stearic acid".

<Component (D)>

AE-EO15: polyoxyethylene alkyl ether. Made by ECOGREEN OLEOCHEMICALS, brand name: "ECOLAT24-15".

AE-EO9: polyoxyethylene alkyl ether. Made by ECOGREEN OLEOCHEMICALS, brand name: "ECOLAT24-9".

AE-EO7: polyoxyethylene alkyl ether. Made by ECOGREEN OLEOCHEMICALS, brand name: "ECOLAT24-7".

AE-EO5: polyoxyethylene alkyl ether. Made by THAI ETHOXYLATE, brand name: "DEHYDOL LS5 TH".

<Component (E)>

Protease 1: Novozymes company make, brand name: "Savinase Ultra 16L".

Protease 2: Novozymes company make, brand name: "Savinase Evity 16L".

Protease 3: Novozymes company make, brand name: "Coronase 48L".

Protease 4: Novozymes company make, brand name: "Medley Core 200L".

<Component (F)>

Citric acid: made by Kanto Chemical Co., Ltd., trade name: "citric acid".

<(G) component>

Silicone preparation: Momentive company make, brand name: "SAG 689".

2H08: Fatty acid 2-ethylhexyl, Lion Specialty Chemicals Co., Ltd. make, brand name: "Pastel 2H-08".

PPG: polyoxypropylene glyceryl ether, manufactured by Mitsui Chemicals Co., Ltd., trade name: "Actcol T-4000", weight average molecular weight 4000.

<Optional ingredients>

MEA: Monoethanolamine, manufactured by Nippon Shokubai Co., Ltd., trade name: "monoethanolamine".

DEA: Diethanolamine, manufactured by Nippon Shokubai Co., Ltd., trade name: "diethanolamine".

Sodium benzoate: Toagosei Co., Ltd. make, brand name: "sodium benzoate."

Para-toluenesulfonic acid: manufactured by Meiyusan Co., Ltd., trade name: "aqueous para-toluenesulfonic acid solution (70% solution)".

Ethanol: Nippon Alcohol Hanbai Co., Ltd. make, brand name: "specific alcohol 95 degree synthesis".

Pigment: Miriken company make, brand name: "Liquitint Blue HP".

PEG1000: Polyethylene glycol #1000, manufactured by Mitsui Chemicals, Inc., trade name: PEG#1000-L60”.

Perfume: Perfume composition A described in Tables 11 to 18 of Japanese Unexamined Patent Publication No. 2002-146399.

48 mass % sodium hydroxide aqueous solution: Kanto Chemical Co., Ltd. make, brand name: "48% sodium hydroxide solution."

Water: Purified water.

[Examples 1 to 23, Comparative Examples 1 to 9]

According to the composition of Table 6 from Table 1, (A) component - (D) component, (E) component - (H) component and arbitrary components were added and mixed in water, and the liquid detergent was obtained. The obtained liquid detergent was evaluated for appearance stability at 0°C and 5°C, foamability (mL), foamability (%), detergency against sebum contamination, and detergency against protein contamination by the following evaluation method. Results are listed in Table 1 through Table 6 together.

In addition, the unit of content in a table|surface is "mass %", and shows a pure part conversion amount. "Balance" means that water is blended so that the compounding amount (mass%) of the total of all compounding components contained in the composition of each example is 100% by mass.

[Evaluation method of bubble height]

A cleaning solution diluted with tap water at 40 ° C. at 2700 ppm (Example 19 is 1000 ppm) of a liquid detergent was added to a glass colorimetric tube (1 mL scale) having a height of 250 mm, an outer diameter of 28 mm and a capacity of 100 mL to the mark of 20 mL. It was shaken 20 times for 10 seconds and left to stand on a flat stand. The bubble volume immediately after shaking (mL) and the bubble volume after 3 minutes of standing (mL) were measured, and the value of the initial liquid level of 20 mL was subtracted from the value of the bubble volume immediately after shaking (mL) or the bubble volume after 3 minutes of standing (mL). found a value Based on this value, foamability (mL) and foamability (%) were calculated according to the following formula, and foamability and foamability of the liquid detergent were evaluated based on the following criteria. It is excellent in low foamability, so that the value of foamability (mL) is small. In addition, the larger the value of the breakability (%), the better the breakability.

Foamability (mL) = (bubble volume immediately after shaking (mL)) - (initial liquid level 20mL)

Breakability (%) = (bubble volume immediately after shaking (mL)) - (foam volume after 3 minutes of standing (mL)) / ((foam volume immediately after shaking (mL)) - (initial liquid level 20mL)) × 100

(Evaluation of foamability (mL))

○: 30 mL or less.

Δ: More than 30 mL and 40 mL or less.

×: Exceeding 40 mL.

(Evaluation of breakability (%))

○: 60% or more.

△: 40% or more and less than 60%.

×: less than 40%.

[Evaluation method of appearance stability]

Two cylindrical glass bottles were prepared, 50 mL of liquid detergent was put into each cylindrical glass bottle, and the lids were closed and hermetically sealed. In this state, each cylindrical glass bottle was left in a thermostat at 0°C or a thermostat at 5°C, and stored for one month. After that, each cylindrical glass bottle was taken out of the thermostat, and the transparent uniformity of the liquid detergent was visually observed, and the external appearance stability of the liquid detergent was evaluated based on the following criteria.

(Evaluation of appearance stability)

○: Transparent uniformity.

x: Solidification or precipitation was confirmed.

[Evaluation method of detergency]

In this method, the measurement of the reflectance of the cloth was performed using an integrating sphere spectrophotometer Color-Eye7000A (manufactured by GretagMacBeth), and the reflectance R was calculated from the Hunter whiteness Z by the following formula.

R=Z/100

First, the reflectance of 10 wet artificially contaminated cloths (sebum contamination, purchased from the Laundry Science Association) and EMPA116 (protein contamination, purchased from Swissatest Testmaterialien AG) were measured as contamination cloths before cleaning. A drum-type washing machine TROM WD-965RD (manufactured by LG) was used as a washing tester, and the washing (setting at 40°C) → spin-drying → rinsing → spin-drying → rinsing → spin-drying → rinsing → spin-drying was set.

The amount of the liquid medical detergent composition used was 36g (Example 19 was 13g), put it in the inlet of the washing machine, and sewed one piece of artificial soiled cloth and EMPA116 to each cotton cloth 1m × 0.8m, and sewn the sewn cotton cloth. I prepared 10 sheets and put them in the washing machine.

After washing, the soiled cloth was separated from the cotton cloth and dried. The reflectance R of the contaminated cloth (hereinafter referred to as cleaning cloth) after drying was measured using a 460 nm filter, and the cleaning rate (unit: %, decimal places are rounded off) by the following formulas (i) and (ii) Calculated.

Cleaning rate (%) = ((dirty spring K/S)-(cleaning cloth K/S))/((dirty spring K/S)-(standard white cloth K/S))×100 … (i)

K/S=(1-R/100) ² /(2R/100)... (ii)

In the formula, K represents an extinction coefficient, S represents a scattering coefficient, and R represents a reflectance. The standard white cloth is an original white cloth (original cloth) that is not contaminated, and the reflectance (R) of the standard white cloth was calculated as 80% for artificially contaminated cloth and 82% for EMPA116.

The higher the value of the cleaning rate obtained from the formulas (i) and (ii), the higher the cleaning power. The average value of the cleaning rates of 10 artificial soil cloths and 10 sheets of EMPA116 was determined, and evaluation was conducted according to the following evaluation criteria.

(Cleansing power (artificially contaminated spring, sebum contamination))

◎, ○, △ were set as pass.

◎: 85% or more.

○: 80% or more and less than 85%.

(triangle|delta): 75 % or more and less than 80 %.

×: less than 75%.

(Detergency (EMPA116, protein contamination))

◎, ○, △ were set as pass.

◎: 70% or more.

○: 68% or more and less than 70%.

(triangle|delta): 65 % or more and less than 68 %.

×: less than 65%.

As shown in Tables 1 to 6, Examples 1 to 23 to which the present invention was applied were "○" or "Δ" in foamability (mL) and breakability (%), and it was confirmed that they were excellent in low foamability. Moreover, it was confirmed that it was excellent in appearance stability. Moreover, the cleaning power was also favorable.

On the other hand, in Comparative Examples 1 to 4 containing no component (B) or component (C), cell breakability (%) and detergency (sebum contamination) were "x". (C) Comparative Examples 5 to 7 in which the /(B) ratio was outside the predetermined range had "×" in foamability (mL) or breakability (%). In Comparative Example 8 not containing component (B) or component (C), cell breakability (%) and detergency (sebum contamination) were "x". In Comparative Example 9, in which the value of (A)/((A)+(D)) was outside the predetermined range, foamability (mL), foamability (%), and detergency (sebum contamination) were all "x".

From these results, according to the present invention, it was found that the cleaning power could be further increased and a medical liquid detergent composition excellent in low foaming properties and foaming properties could be provided.

Claims (3)

(A) component: an anionic surfactant excluding soap,
(B) component: a fatty acid having 12 carbon atoms or a salt thereof;
(C) component: a fatty acid having 14 to 18 carbon atoms or a salt thereof;
(D) component: containing a nonionic surfactant,
(A) The mass ratio represented by component / ((A) component + (D) component) is 0.2 or more and less than 0.9, and the mass ratio represented by (C) component / (B) component is 0.05 or more and 0.38 or less,
Moreover, the medical liquid detergent composition whose content of (A) component is 2.7 mass % or more and 8.5 mass % or less with respect to the gross mass of liquid detergent composition. According to claim 1,
(E) Component: The medical liquid detergent composition containing an enzyme further. According to claim 1 or 2,
Component (F): The medical liquid detergent composition further containing a chelating agent.