KR102486540B1 - Reagent analysis device and method of controlling the same - Google Patents

Abstract

A reagent analysis device according to one embodiment of the present document comprises: a camera unit including a camera equipped with a sensor; a reagent seating unit where a reagent is sprayed; a memory for storing data about images obtained by the camera; a display for visually displaying the data about the images; and a control unit electrically connected to the camera unit, the memory, and the display. The control unit may obtain an image of the reagent seating unit by using the camera, obtain a focused region of interest image from the image of the reagent seating unit, and obtain a focused analysis target image from the region of interest image. According to the embodiments of the present document, smooth experimentation/diagnosis/analysis can be performed by quickly obtaining focused images even when an object of observation or the camera moves.

Description

Reagent analysis device and control method of the reagent analysis device {REAGENT ANALYSIS DEVICE AND METHOD OF CONTROLLING THE SAME}

Various embodiments according to this document relate to a reagent analysis device and a control method of the reagent analysis device.

As research on various diseases and viruses is actively progressing, the development of equipment necessary for experiments, diagnosis and analysis is also progressing widely. In order to analyze diseases, viruses, allergies, etc., devices capable of observing chemical reactions occurring in a container or area into which a reagent for analysis/diagnosis is sprayed are required.

According to the prior art, when the object of observation moves or the camera moves while observing the container/region into which the reagent, which is the object of observation, is sprayed using a camera, the focus of the image acquired through the camera is lost in the middle of observation or , it had to be refocused each time it moved. In this case, since it takes time to acquire a focused image through the camera, it is difficult or time-consuming to conduct a smooth experiment/diagnosis/analysis. In addition, when the camera acquires an image while moving along with the component for dispensing the reagent, a problem such as a misalignment between the direction of the camera and the component for dispensing the reagent may occur.

The problem to be solved by this document is to provide a reagent analysis device and a control method of the reagent analysis device capable of conducting smooth experiment/diagnosis/analysis by quickly obtaining a focused image.

An object to be solved by this document is to provide a reagent analysis device provided to operate a camera separately from a configuration for spraying a reagent and a control method of the reagent analysis device.

The technical problem to be achieved in this document is not limited to the technical problem mentioned above, and other technical problems not mentioned can be clearly understood by those skilled in the art from the description below. There will be.

A reagent analysis device according to an embodiment of the present document includes a camera unit including a camera equipped with a sensor, a reagent seating unit in which a reagent is sprayed, a memory for storing data about images acquired by the camera, and a display for visually displaying data for the sample and a control unit electrically connected to the camera unit, the memory, and the display, wherein the control unit obtains an image of the reagent seating unit using the camera, and obtains an image of the reagent seating unit from the image A focused region-of-interest image may be obtained, and a focused analysis target image may be acquired from among the region-of-interest images.

The camera may independently and relatively move left and right with respect to the reagent seating part.

The control unit: performs zoom-in/zoom-out of the reagent seating portion image using the camera, obtains a first image parameter for a region of interest in real time while zooming in, and uses the first image parameter. Thus, the ROI image may be focused.

The control unit: performs image segmentation of the reagent seating unit image into a plurality of regions having sizes corresponding to the region of interest image based on the image database stored in the memory, and performs image segmentation on the region of interest based on the image segmentation. You can focus the image,

The control unit may: identify a second image parameter for the analysis target image from among the ROI images, and focus the analysis target image based on the second image parameter.

The camera unit further includes a rail to which the camera unit is movably coupled, the camera includes a plurality of cameras having different angles of view, and while the camera unit moves along the rail, the control unit: uses the plurality of cameras. to obtain the reagent seating part image and the region-of-interest image including an overlapping region, obtain image data of the plurality of images including at least overlapping data for the overlapping region, and obtain the image data of the plurality of images Focusing on an image of the region of interest among the plurality of images may be performed using image data for the .

According to the embodiments of the present document, even when an object of observation moves or a camera moves, a focused image can be quickly obtained, so that experiments/diagnosis/analysis can be performed smoothly.

According to the embodiments of the present document, since the camera operates separately from the component for spraying the reagent, an accurate image can be effectively obtained without being affected by other components.

Effects obtainable based on various embodiments are not limited to the effects mentioned above, and other effects not mentioned are clearly understood by those skilled in the art from the description below. It could be.

1 is a diagram showing the configuration of a reagent analyzer 1 according to an embodiment of the present document.
2 is a view showing the appearance of the reagent analyzer 1 according to an embodiment of the present document.
FIG. 3 is a view showing the arrangement of the camera unit 110 and the reagent seating unit 120 of the reagent analyzer 1 according to an embodiment of the present document.
4 is a diagram illustrating the camera unit 110 according to an embodiment of the present document.
5 is a diagram for explaining the operation of the camera unit 110 and the reagent seating unit 120 according to an embodiment of the present document.
6 is a diagram for explaining an optical path of the camera unit 110 according to an embodiment of the present document.
7 is a flowchart for explaining a basic flow of operation of the reagent analyzer 1 according to an embodiment of the present document.
8 and 9 are diagrams illustrating a reagent seating part image 300-1 and a region-of-interest image 310-1 according to an embodiment of the present document.
10 and 11 are diagrams illustrating a reagent seating part image 300-1 and a region of interest image 310-1 according to an embodiment of the present document.
12 is a flowchart illustrating a first flow of operation of the reagent analyzer 1 according to an embodiment of the present document.
13 is a flowchart for explaining a second flow of operation of the reagent analyzer 1 according to an embodiment of the present document.
14 is a flowchart illustrating a third flow of operation of the reagent analyzer 1 according to an embodiment of the present document.
15 is a flowchart illustrating a fourth flow of operation of the reagent analyzer 1 according to an embodiment of the present document.
In connection with the description of the drawings, the same or similar reference numerals may be used for the same or similar elements.

The embodiments described in this specification and the configurations shown in the drawings are only one preferred example of the disclosed invention, and there may be various modifications that can replace the embodiments and drawings in this specification at the time of filing of the present application.

The same reference numerals or numerals presented in each drawing in this specification indicate parts or components that perform substantially the same function. The shapes and sizes of elements in the drawings may be exaggerated for clarity.

Terms used in this specification are used to describe the embodiments, and are not intended to limit and/or limit the disclosed invention. Singular expressions include plural expressions unless the context clearly dictates otherwise. In this specification, terms such as “include” or “have” are intended to designate that there is a feature, number, step, operation, component, part, or combination thereof described in the specification, but one or more other features It does not preclude in advance the existence or addition of numbers, steps, operations, components, parts, or combinations thereof.

Terms including ordinal numbers such as “first” and “second” used herein may be used to describe various components, but the components are not limited by the terms, and the terms are one It is used only for the purpose of distinguishing a component from other components. For example, a first element may be termed a second element, and similarly, a second element may be termed a first element, without departing from the scope of the present invention. The term “and/or” includes any combination of a plurality of related recited items or any one of a plurality of related recited items.

The terms "top", "bottom", "left", "right", etc. used below are defined based on the drawings, and the shape and location of each component are not limited by these terms.

It will be appreciated that each block of process flow diagrams and combinations of flow diagrams may be performed by computer program instructions. Since these computer program instructions may be loaded into a processor of a general purpose computer, special purpose computer, or other programmable data processing equipment, the instructions executed by the processor of the computer or other programmable data processing equipment are described in the flowchart block(s). It creates the means to perform the specified functions. These computer program instructions may also be stored in a computer usable or computer readable memory that can be directed to a computer or other programmable data processing equipment to implement functionality in a particular way, such that the computer usable or computer readable memory The instructions stored in are also capable of producing an article of manufacture containing instruction means that perform the functions described in the flowchart block(s). The computer program instructions can also be loaded on a computer or other programmable data processing equipment, so that a series of operational steps are performed on the computer or other programmable data processing equipment to create a computer-executed process to generate computer or other programmable data processing equipment. Instructions for performing processing equipment may also provide steps for performing the functions described in the flowchart block(s).

Additionally, each block may represent a module, segment or portion of code including at least one executable instruction for executing specified logical function(s). It should also be noted that in some alternative implementations it is possible for the functions mentioned in the blocks to occur out of order. For example, two blocks shown in succession may in fact be executed substantially concurrently, or the blocks may sometimes be executed in reverse order depending on their function.

At this time, the term '~unit' used in this embodiment means software or a hardware component such as a field-programmable gate array (FPGA) or application specific integrated circuit (ASIC), and what role does '~unit' have? perform them However, '~ part' is not limited to software or hardware. '~bu' may be configured to be in an addressable storage medium and may be configured to reproduce one or more processors. Therefore, as an example, '~unit' refers to components such as software components, object-oriented software components, class components, and task components, processes, functions, properties, and procedures. , subroutines, segments of program code, drivers, firmware, microcode, circuitry, data, databases, data structures, tables, arrays, and variables. Functions provided within components and '~units' may be combined into smaller numbers of components and '~units' or further separated into additional components and '~units'. In addition, components and '~units' may be implemented to play one or more CPUs in a device or a secure multimedia card.

Hereinafter, various embodiments will be described in detail with reference to the accompanying drawings.

1 shows a configuration diagram of a reagent analysis device 1 according to an embodiment of the present document.

The reagent analyzer 1 may include a camera unit 110 .

The camera unit 110 may include a camera 200 equipped with a sensor 201 . For example, the sensor 201 may be provided in the camera 200 or may be disposed around the camera 200 . The sensor 201 may include a distance sensor.

The reagent analysis device 1 may include a reagent seating part 120 . For example, a plurality of containers into which reagents may be sprayed may be seated in the reagent seating unit 120 . In addition, the reagent seating part 120 may be composed of a plurality of areas where reagents can be sprayed and deposited.

The reagent analysis device 1 may include a memory 130 . For example, the memory 130 may store image data. Also, the memory 130 may include a main memory and a buffer memory. The main memory may store image data obtained through the camera 200 or a pre-stored image database for a long period of time. The buffer memory may store image data to be temporarily stored and utilized between the controller 150 and the camera 200, which will be described later.

The reagent analysis device 1 may include a display 140 . For example, the display 140 may visually display image data to provide a user with an image based on the image data. In addition, the display 140 may visually display and provide images acquired by the reagent analysis device 1 using the camera unit 110 to the user.

The reagent analysis device 1 may include a controller 150. The controller 150 may be electrically and operatively connected to the camera unit 110 , the memory 130 , and the display 140 . For example, the controller 150 is electrically and operatively connected to the camera unit 110, the memory 130, and the display 140 to operate the camera unit 110, the memory 130, and the display 140. can control them.

2 shows an appearance of a reagent analysis device 1 according to an embodiment of the present document.

The reagent analyzer 1 may include a body part 2 . For example, the body unit 2 may include a camera unit 110, a reagent seating unit 120, a memory 130, and a control unit 150 to form a main body of the reagent analysis device 1. In this case, the display 140 may be coupled to the outer shell of the body portion 2 . However, this is exemplary, and the display 140 may be included in the body portion 2 and configured.

3 shows the arrangement of the camera unit 110 and the reagent seating unit 120 of the reagent analyzer 1 according to an embodiment of the present document.

3 may show the inside of the reagent analyzer 1.

The reagent seat 120 may be fixedly disposed on the reagent analyzer 1 .

The camera unit 110 may be coupled to the rail 111 so as to move in the x-axis direction with respect to the reagent seating unit 120 . For example, the camera unit 110 may be coupled to the rail 111 so as to move along the +x axis or -x axis with respect to the reagent seating unit 120 . The camera unit 110 may acquire images while moving along the rail 111 .

4 shows a camera unit 110 according to an embodiment of the present document, FIG. 5 shows operations of the camera unit 110 and the reagent seating unit 120 according to an embodiment of the present document, and FIG. An optical path of the camera unit 110 according to an embodiment of the present document is shown.

Hereinafter, the camera unit 110 and the reagent seating unit 120 will be described with reference to FIGS. 4 to 6 .

The camera unit 110 may include a camera 200 . For example, the camera 200 may include a sensor 201 therein. However, the sensor 201 may be disposed around the camera 200 without being limited thereto.

The camera 200 may include a plurality of cameras having different angles of view. For example, among the plurality of cameras, a first camera may have a first angle of view, and a second camera may have a narrower angle of view than the first angle of view. In addition, the camera 200 is not limited to the two cameras described above, and may include three or more cameras according to design.

The camera 200 may acquire an external image through the first mirror 221 . For example, the first mirror 221 may be disposed on the optical axis of the camera 200 . The first mirror 221 may be disposed to form a predetermined angle with the optical axis of the camera 200 . The first mirror 221 may be disposed on the optical axis so as to form a predetermined angle with respect to the surface formed by the reagent seating part 120 . The light reflected from the reagent holder 120 is reflected from the first mirror 221 , and the light reflected from the first mirror 221 can be received by the camera 200 . For another example, the light reflected by the reagent holder 120 may be reflected by the first mirror 221 and received in the camera 200 parallel to the optical axis of the camera 200 .

The camera 200 may perform zoom-in/zoom-out. For example, the camera 200 may perform zoom-in to enlarge an external image, and may perform zoom-out to acquire an image of a wider field of view with respect to an external image.

The sensor 201 may include a distance sensor (eg, a TOF sensor). When the sensor 201 is provided inside the camera 200, the distance data from the camera 200 to the first mirror 221 and the distance from the first mirror 221 to the reagent seating part 120 are obtained and Calculate the total distance. For example, when the reagent seating portion 120 has a shape having a height, the sensor 201 may detect the height of the reagent seating portion 120 by detecting the total distance. For example, the sensor 201 may calculate that the total distance of an area formed with a relatively low height in the reagent seating part 120 is greater than the total distance of an area formed with a relatively high height. The reagent analyzer 1 may use the sensor 201 to distinguish regions where the above-described total distances correspond to each other.

The camera unit 110 may include a first lighting unit 211 capable of generating illumination light. For example, the first lighting unit 211 may be disposed around the camera 200 . Illumination light generated from the first lighting unit 211 may reach the reagent seating unit 120 . The path of the illumination light generated by the first lighting unit 211 may be changed by adjusting the angle of the first lighting unit 211 .

The camera unit 110 may include a second lighting unit 212 capable of generating illumination light. The camera unit 110 may include a second mirror 222 that reflects illumination light generated by the second lighting unit 212 . For example, illumination light generated by the second lighting unit 212 may be reflected by the second mirror 222 and reach the reagent seating unit 120 . The path of the illumination light generated by the second lighting unit 211 may be changed by adjusting the angle of the second lighting unit 212 .

The reagent seating portion 120 may have a height. For example, the reagent seating portion 120 may include a low area formed with a groove in which reagents can be placed on the plate. In this case, the recessed low region in which the groove is formed may have a low height, and the height of regions other than the low region may be relatively high. A low region of the reagent seating portion 120 in which a recess is formed may have a specific shape (eg, a rectangle). The aforementioned low area may be a reagent accommodating area in which reagents may be accommodated, and the reagent seating portion 120 may include a plurality of reagent accommodating areas. One of the plurality of reagent accommodating regions may be the region of interest. However, this is an example and may not be limited thereto.

The reagent analyzer 1 calculates the distance from the camera 200 to the first mirror 221 and the distance from the first mirror 221 to the reagent seating part 120 using the sensor 201 and calculates the total distance. distance can be sensed. The reagent analyzer 1 may detect that the total distance of the low-height region of the above-described reagent seating portion 120 is greater than the total distance of the high-height region, and the above-described reagent among the reagent seating portion 120 Receptive areas can be identified.

The camera unit 110 may obtain an image of the reagent seating unit 120 (eg, a reagent seating unit image) through the camera 200 while moving by a predetermined interval on the rail 111 .

The reagent analyzer 1 may display images acquired through the camera 200 on the display 140 under the control of the controller 150 . For example, the reagent analyzer 1 may display on the display 140 so that the x-axis direction of the reagent seating portion 120 is the vertical direction of the display 140, and the x-axis direction of the reagent seating portion 120 It may be displayed on the display 140 so that the direction is the left and right direction of the display 140.

The reagent analyzer 1 may obtain an image (eg, an ROI image) of a region of interest necessary for analysis from among the reagent seating part images acquired through the camera unit 110, and when the image of the region of interest is obtained, the region of interest may be obtained. An analysis target image included in the region image may be obtained. The reagent analyzer 1 may acquire images while performing focusing on each image during the above-described process.

Hereinafter, the focusing operation of the reagent analyzer 1 will be described.

7 shows a basic flow of operation of the reagent analyzer 1 according to an embodiment of the present document. 8 and 9 show a reagent seating part image 300-1 and an ROI image 310-1 according to an embodiment of the present document, and FIGS. 10 and 11 show reagents according to an embodiment of the present document. The seating portion image 300-2 and the ROI image 310-2 are shown.

The flow of FIG. 7 will be described with reference to FIGS. 8 to 11 , and operations of the reagent analyzer 1 may be controlled by the control unit 150 .

According to an embodiment, in operation S11 , the reagent analyzer 1 may obtain the reagent seating part images 300-1 and 300-2.

The reagent analyzer 1 may acquire the reagent seating part image 300-1 using the camera 200. The reagent seating portion image 300-1 may be an image of the reagent seating portion 120 including a plurality of reagent accommodating areas.

According to an embodiment, in operation S12 , the reagent analyzer 1 may obtain the focused region-of-interest images 310-1 and 310-2 among the reagent holder images 300-1 and 300-2. .

The region of interest image 310 - 1 may be an image of a region of interest, which is one of a plurality of reagent accommodating regions. The region of interest may be determined according to user settings. For example, the user may set a specific region of the reagent holder image 300-1 including a plurality of reagent receiving regions as a region of interest. As for the setting method, the user may select a specific region from among the portions displayed on the display 140, or it may be automatically selected, and there may be no particular limitation.

The reagent analyzer 1 may acquire a focused region-of-interest image 310-1 from among the reagent-mounting part image 300-1 based on a user's acquisition of an input for selecting a specific region or automatic selection.

The description of the above-described reagent seating unit image 300-1 and the focused ROI image 310-1 may also be applied to the reagent seating unit image 300-2 and the focused ROI image 310-2. there is.

According to an embodiment, in operation S12 , the reagent analysis device 1 may acquire focused analysis target images 311 and 322 from among the focused ROI images 310 - 1 .

The reagent analysis device 1 may acquire an analysis target image 311 from among the focused region-of-interest images 310-1. For example, when a region containing a reagent to be analyzed exists in the ROI image 310 - 1 , the reagent analyzer 1 may acquire the region including the reagent as the analysis target image 311 .

Description of the above-described reagent seating portion image 300-1, the focused region of interest image 310-1, and the analysis target image 311 is the reagent seating portion image 300-2, the focused region of interest image ( 310-2), and may also be applied to the analysis target image 322.

12 shows a first flow of operation of the reagent analyzer 1 according to an embodiment of the present document. The flow of FIG. 12 will be described with reference to FIGS. 8 to 11 , and operations of the reagent analyzer 1 may be controlled by the control unit 150 .

After operation S11 according to an embodiment, operation S21 may be performed.

According to an embodiment, in operation S21, the reagent analyzer 1 may perform zoom-in on the reagent seating part image 300-1.

The reagent analyzer 1 may acquire distance data for the reagent seating part image 300-1 using the sensor 201. For example, the reagent analyzer 1 may obtain distance data about heights of a plurality of reagent accommodating regions. The reagent analyzer 1 may identify a plurality of reagent accommodating regions of the reagent holder image 300-1 using the acquired distance data. In this case, the reagent analyzer 1 may obtain distance data for the reagent seating part image 300-1 corresponding to the current zoom-in state.

According to an embodiment, in operation S22, the reagent analyzer 1 may acquire image parameters in real time while zooming in.

The reagent analyzer 1 may obtain image data (eg, distance data that is changed in real time) while zooming in on the reagent holder image 300 - 1 using the camera 200 . For example, while performing zoom-in, the reagent analyzer 1 may obtain an enlarged reagent seating part image 300-1 while acquiring distance data that changes in real time using a camera. The reagent analyzer 1 may obtain an enlarged reagent seating part image 300-1 centered on the region of interest while identifying a region of interest among a plurality of reagent accommodating regions of the reagent seating part image 300-1. . In this case, the reagent analyzer 1 can acquire image data for the reagent holder image 300-1 being enlarged in real time while performing zoom-in, thereby reducing the time required for focusing. .

According to an embodiment, in operation S23, the reagent analyzer 1 may focus the ROI image 310-1 using the image parameter.

The reagent analyzer 1 may perform focusing on the ROI image 310-1 among the reagent seating part images 300-1 that are enlarged around the ROI using the obtained distance data.

Since the reagent analyzer 1 enlarges the reagent seating part image 300-1 while continuously identifying the region of interest using the distance data obtained in real time while performing zoom-in, the region of interest image 310-1 There is an effect that focusing on can be quickly performed.

Description of the above-described reagent seating portion image 300-1, the focused region of interest image 310-1, and the analysis target image 311 is the reagent seating portion image 300-2, the focused region of interest image ( 310-2), and may also be applied to the analysis target image 322.

Distance data acquired by the reagent analyzer 1 through the sensor 201 may be temporarily stored in the buffer memory of the memory 130 and may be immediately utilized. As described above, if the distance data is temporarily stored in the buffer memory, since the reagent analyzer 1 uses the distance data for focusing quickly, there is an effect that focusing can be performed quickly.

13 shows a second flow of operation of the reagent analyzer 1 according to an embodiment of the present document. In the flow of FIG. 13 , described with reference to FIGS. 8 to 11 , operations of the reagent analyzer 1 may be controlled by the control unit 150 .

After operation S11 according to an embodiment, operation S31 may be performed.

Operations S31 to S32 may be performed in parallel or serially with operations S21 to S23.

According to an embodiment, in operation S31, the reagent analyzer 1 converts the reagent seating part image 300-1 to the region of interest image 310-1 based on the image database stored in the memory 130. Image segmentation can be performed into a plurality of areas having sizes.

The memory 130 may form an image database. For example, the image database includes distance data acquired by the sensor 201 according to zoom-in/zoom-out of the camera 200, the size of the reagent holder image 300-1, and the region-of-interest image 310-1. It may include a plurality of region data corresponding to the relative size of and the relative size of the region-of-interest image 310-1. Distance data acquired by the sensor 201 according to the above-described zoom-in/zoom-out of the camera 200, the size of the reagent holder image 300-1, the relative size of the ROI image 310-1, and the ROI The plurality of area data corresponding to the relative size of the image 310-1 may be data learned by machine learning in an external device. However, it is not limited thereto.

The reagent analyzer 1 may perform image segmentation into a plurality of reagent accommodating regions in the obtained reagent seating part image 300-1 based on the image database.

According to an embodiment, in operation S32, the reagent analyzer 1 may focus the ROI image 310-1 among the plurality of regions.

The reagent analyzer 1 performs image segmentation into a plurality of reagent accommodating regions in the acquired reagent seating part image 300-1 based on the image database to identify a region of interest, which is one of the plurality of reagent accommodating regions. can For example, the reagent analysis device 1 obtains an input selected by a user or automatically selects one of the region of interest image-divided into a plurality of regions (eg, a plurality of reagent accommodating regions) to obtain an image of the region of interest. (310-1).

The reagent analysis device 1 may perform focusing on the acquired ROI image 310-1.

As described above, when the reagent analysis device 1 uses the image database generated by machine learning, the reagent seating portion image 300-1, the region of interest image 310-1, and the analysis target image 311 There is an effect that the classification can be performed more quickly.

Description of the above-described reagent seating portion image 300-1, the focused region of interest image 310-1, and the analysis target image 311 is the reagent seating portion image 300-2, the focused region of interest image ( 310-2), and may also be applied to the analysis target image 322.

14 shows a third flow of operation of the reagent analyzer 1 according to an embodiment of the present document. The flow of FIG. 14 will be described with reference to FIGS. 8 to 11 , and operations of the reagent analyzer 1 may be controlled by the control unit 150 .

After operation S12 according to an embodiment, operation S41 may be performed.

According to an embodiment, in operation S41, the reagent analyzer 1 may identify an image parameter for the analysis target image 311 from among the ROI image 310-1.

The reagent analysis device 1 may identify image parameters of the analysis target image 311 . For example, the image parameter of the analysis target image 311 may include a specific shape (eg, a curved shape), a specific color containing a reagent, or distance data different from the reagent accommodating region. However, it may not be limited now.

According to an embodiment, in operation S42, the reagent analysis device 1 may perform focusing on the analysis target image 311 using the identified image parameter of the analysis target image 311.

The above description of the focused region-of-interest image 310-1 and the analysis target image 311 may also be applied to the focused region-of-interest image 310-2 and the analysis target image 322.

15 shows a fourth flow of operation of the reagent analyzer 1 according to an embodiment of the present document. The flow of FIG. 15 will be described with reference to FIGS. 8 to 11 , and operations of the reagent analyzer 1 may be controlled by the control unit 150 .

Operations S51 to S54 described below may be performed in parallel with operations S21 to S23, operations S31 to S32, and/or operations S41 to S42, or may be performed serially.

According to an embodiment, the camera 200 may include a plurality of cameras having different angles of view. For example, among the plurality of cameras, a first camera may have a first angle of view, and a second camera may have a narrower angle of view than the first angle of view.

Operations S51 to S54 described later may be applied even when the camera unit 110 moves along the rail 111 .

According to an embodiment, in operation S51, the reagent analyzer 1 may acquire a plurality of images including overlapping regions by using a plurality of cameras having different angles of view.

The reagent analyzer 1 may obtain an image having a size corresponding to the reagent holder image 300-1 by using a camera having a first angle of view. The reagent analysis device 1 may obtain an image having a size including the ROI image 310-1 by using a camera having a second angle of view. In this case, an image having a size corresponding to the reagent seat image 300-1 may include an image having a size including the region of interest image 310-1, and including the region of interest image 310-1. The image of the size may be an overlapping area.

According to an embodiment, in operation S52, the reagent analyzer 1 may obtain image information on a plurality of images.

The reagent analyzer 1 has an image (or a first image) having a size corresponding to the reagent seating portion image 300-1 and an image (or a second image) having a size including the ROI image 310-1. Image information (or data) can be obtained. For example, the image information (or data) may be overlapping data about sizes and relative positions of overlapping regions of the first and second images, and distance data between the first and second images, respectively. In addition, the image information may include size, relative position, and distance data of an analysis target (eg, a region including a reagent) included in the second image.

According to an embodiment, in operation S53, the reagent analyzer 1 may perform focusing on one image among a plurality of images by using the acquired image information.

The reagent analyzer 1 uses the size and relative position of the overlapping region of the first image and the second image and the distance data between the first image and the second image, respectively, to determine the size of the region of interest image 310-1. It is possible to perform focusing on the image (or the second image) of . For example, the reagent analyzer 1 may display the first image and/or the second image on the display 140, and obtain a user's input for selecting the second image or automatically select the second image on the display 140. Accordingly, focusing on the second image may be performed using the acquired image information for each image.

According to an embodiment, in operation S54, the reagent analyzer 1 may acquire one focused image.

The reagent analyzer 1 may acquire an image (or the ROI image 310 - 1 ) in which the second image is focused according to the focusing of the second image performed in operation S53 .

The reagent analysis device 1 may perform additional focusing on the analysis target image 311 included in the second image by using the image information (or data) obtained in operation S51.

As described above, the reagent analysis device 1 obtains a plurality of images including overlapping regions using a plurality of cameras, so that even when the camera unit 110 moves along the rail 111, the plurality of images are obtained. Relationships and distance data between images can be more easily sensed, and focusing on images can be performed quickly.

Description of the above-described reagent seating portion image 300-1, the focused region of interest image 310-1, and the analysis target image 311 is the reagent seating portion image 300-2, the focused region of interest image ( 310-2), and may also be applied to the analysis target image 322.

As such, various embodiments of the present invention may be implemented as computer readable codes in a computer readable recording medium from a specific point of view. A computer readable recording medium is any data storage device capable of storing data that can be read by a computer system. Examples of computer readable recording media include read only memory (ROM), random access memory (RAM), and compact disk-read only memory (CD-ROM). ), magnetic tapes, floppy disks, optical data storage devices, and carrier waves (such as data transmission over the Internet). The computer readable recording medium may also be distributed across networked computer systems, so that computer readable code is stored and executed in a distributed manner. In addition, functional programs, code, and code segments for achieving various embodiments of the present invention can be easily interpreted by programmers skilled in the field to which the present invention is applied.

It will also be appreciated that devices and methods according to various embodiments of the present invention can be realized in the form of hardware, software, or a combination of hardware and software. Such software may include, for example, a volatile or non-volatile storage device such as a ROM, whether removable or rewritable, or a memory such as, for example, RAM, a memory chip, device or integrated circuit, or For example, it may be stored in an optically or magnetically recordable and machine-readable storage medium such as a compact disk (CD), DVD, magnetic disk, or magnetic tape. Methods according to various embodiments of the present invention may be implemented by a computer or portable terminal including a processor and/or memory, and the memory stores a program or programs including instructions for implementing the embodiments of the present invention. It will be appreciated that this is an example of a machine-readable storage medium suitable for:

Accordingly, the present invention includes a program including code for implementing the device or method described in the claims of this specification and a storage medium readable by a machine (such as a computer) storing such a program. In addition, such a program may be transmitted electronically through any medium, such as a communication signal transmitted through a wired or wireless connection, and the present invention appropriately includes equivalents thereto.

In the above, specific embodiments have been illustrated and described. However, it is not limited to the above embodiments, and those skilled in the art will be able to make various changes without departing from the gist of the technical idea of the invention described in the claims below. .

One; reagent analysis device
2; body part
110; camera part
120; Reagent loading part
130; Memory
140; display
150; control unit

Claims (5)

In the reagent analysis device,
a camera unit including a camera equipped with a sensor;
Reagent seating portion to which the reagent is sprayed;
a memory for storing data about images acquired by the camera;
a display that visually displays data for the images; and
A control unit electrically connected to the camera unit, the memory, and the display;
The control unit:
Obtaining an image of the reagent mounting portion using the camera,
Obtaining a focused region of interest image among the reagent seating part images;
Obtaining a focused analysis target image among the ROI images;
The control unit:
Performing zoom-in/zoom-out of the reagent mounting portion image using the camera;
Obtaining a first image parameter for a region of interest in real time during the zoom-in;
Focusing the ROI image using the first image parameter;
The control unit:
Based on the image database stored in the memory, performing image segmentation of the reagent seating part image into a plurality of regions having sizes corresponding to the image of the region of interest;
Focusing the ROI image based on the image segmentation;
The control unit:
Among the ROI images, a second image parameter for the analysis target image is identified;
Focusing the analysis target image based on the second image parameter;
The reagent analysis device further includes a rail to which the camera unit is movably coupled,
The camera includes a plurality of cameras having different angles of view,
While the camera unit moves along the rail, the control unit:
Obtaining an image of the reagent seating portion and an image of the region of interest including an overlapping region using the plurality of cameras;
Obtaining image data for the plurality of images including at least overlapping data for the overlapping region;
And performing focusing on the ROI image among the plurality of images by using image data of the plurality of images.
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Images