KR102400814B1 - Patch for tooth whitening and tooth whitening device comprising the same - Google Patents

Abstract

The present invention relates to a tooth whitening method, and more particularly, to a tooth whitening patch, an apparatus including the same, or a tooth whitening method using the same. In particular, the present invention provides a tooth whitening device comprising (a) a light irradiation device for irradiating light for teeth whitening, and (b) a multi-layered tooth whitening patch, wherein the irradiated light contains a whitening active ingredient contained in the patch. It is characterized in that it is activated efficiently.

Description

Tooth whitening patch and tooth whitening device including the same {Patch for tooth whitening and tooth whitening device comprising the same}

The present invention relates to a tooth whitening method, and more particularly, to a tooth whitening patch, an apparatus including the same, or a tooth whitening method using the same.

Recently, white teeth have been established as one of the objects of aesthetic pursuit. Since many people are not satisfied with the color of their teeth and want to have whiter teeth, there is a trend in the development of teeth whitening products as well as teeth whitening procedures.

A well-known tooth whitening procedure involves applying a whitening agent containing a high concentration of whitening ingredients to the teeth and irradiating special light for a short period of time to activate the whitening ingredients contained in the tooth whitening agent to whiten teeth several times. There is a method in which a whitening agent containing a whitening component is applied to teeth and left for a long time is repeated several times, or a tooth patch containing a whitening agent is attached to the teeth and repeated several times.

Also, a well-known whitening ingredient is hydrogen peroxide. Hydrogen peroxide can whiten teeth, remove discolored stains, and has antibacterial properties in the mouth. Accordingly, many tooth whitening agents contain hydrogen peroxide, thereby imparting a chemical whitening effect to the teeth.

In general, teeth whitening procedure that irradiates special light uses high concentration of hydrogen peroxide that can cause cell damage and irritation in the oral cavity, so it is performed with the help of a professional such as a dentist. It was a situation in which a method for attaching a tooth whitening patch was mainly performed.

However, there has been a problem that a tooth whitening procedure irradiating a special light has a large burden on consumers in terms of cost, and the self-whitening method at home has a problem that the effect is insufficient. In order to solve this problem and provide the same teeth whitening procedure at home as in dentistry, a tooth whitening kit including a light irradiation device irradiating a special light as a method of self-whitening has been developed and distributed in the market. .

On the other hand, the whitening effect of the light irradiation tooth whitening method mainly used in dentistry or the light irradiation tooth whitening method carried out using a kit at home as described above depends on the intensity, wavelength, and irradiation time of light, etc., and the irradiated light is whitening Since light energy is not efficiently transmitted to the whitening component because it is reflected or refracted by factors other than the component, for example, the tooth tray itself coated with the whitening agent, the light irradiation tooth whitening method still improves the effect of teeth whitening need to be

On the other hand, when light travels from medium A to another medium B, some of the light is reflected at the interface and most of the other light is refracted and entered. The relative refractive index of medium A with respect to medium B is expressed as n _BA , and the relationship between the angle of incidence α and the angle of refraction β follows Snell's law, < sin β/sin α = n _BA >.

Therefore, the problem to be solved by the present invention is to solve the above problems and to improve the effect of whitening teeth.

Another object of the present invention is to provide a method of delivering a sufficient amount of light energy to a tooth whitening component by improving the absorbance of a patch in tooth whitening using light irradiation.

In order to solve the above problems, the present invention is (a) a light irradiation device for irradiating light for teeth whitening; And (b) provides a tooth whitening device comprising a multi-layered tooth whitening patch.

In the method of whitening teeth by irradiating light, the present inventors have found that, when the tooth whitening agent is directly applied to the teeth, problems such as excessive tooth irritation and tooth enamel damage occur, and cell damage occurs when in contact with oral cells other than teeth. recognized the problem. In addition, when a whitening agent is applied to a tray and the tray is in contact with teeth to irradiate light, the light is reflected and refracted by the tray, so that the whitening active ingredient included in the whitening agent is inefficiently activated. The present inventors conducted research to provide a device capable of irradiating light by attaching a tooth whitening patch to teeth in order to solve this problem. In particular, the present invention was completed as a result of conducting research to provide a patch through which the light irradiated for the activation of the whitening active ingredient contained in the patch is efficiently transmitted.

In the specification of the present invention, "light for teeth whitening" may refer to light irradiated to teeth, which is used in a light irradiation device used by a professional in dentistry, a self teeth whitening device, and the like. Any light irradiated for teeth whitening may be included in the 'light for teeth whitening' of the present invention without any particular limitation on the treatment site, the treatment device, or the like.

Preferably, it may have a wavelength of 380 to 540 nm, more preferably 400 to 520 nm, and is commonly referred to as 'blue light' or 'white light'.

The light irradiation device included in the tooth whitening device of the present invention is a device commonly used when whitening teeth by irradiating light, and is not particularly limited.

In addition, the present invention provides a tooth whitening device, including a light emitting diode (LED, light emitting diode) device, a light irradiation device comprising at least one selected from the group consisting of a laser (laser), and a UV lamp.

The present invention provides a tooth whitening device further comprising (c) an opening device.

The opening device means a device that assists in opening the mouth so that the irradiated light can reach the tooth to which the patch is attached evenly, and the opening device included in the present invention is normally used as an oral opening device. not.

In addition, the (b) multi-layered tooth whitening patch 1 of the present invention may include a support layer 20 , an adhesive layer 10 , and a light absorption layer 40 .

One layer of the multilayer structure, the light absorption layer 40 , is a layer that increases the absorbance of the patch 1 , and may include a polymer having a lower refractive index than that of the support layer 20 .

For example, when the present inventors express the refractive index of the light absorption layer 40 as n1 and the refractive index of the support layer 20 as n2, the tooth whitening patch 1 satisfying n1/n2 < 1 is the light absorption layer It was confirmed that the absorbance of the patch was increased when compared to the tooth whitening patch of the same thickness that did not contain it.

The light absorbing layer 40 is understood to mean a polymer layer that serves to increase the absorbance of the tooth whitening patch of the present specification.

The light absorption layer 40 includes a polymer having a low refractive index, but is not limited thereto, for example, ethyl cellulose (EC), hydroxypropyl cellulose (HPC), polyvinyl alcohol (PVA), carboxymethyl cellulose (CMC), or these It may include a mixture of, preferably carboxymethyl cellulose or ethyl cellulose. Most preferably, for the purpose of the present invention, a polymer having a refractive index smaller than that of the polymer included in the support layer 20 is included.

The support layer 20 includes a water-insoluble polymer, and the whitening active ingredient included in the patch 1 can prevent cell damage due to contact with cells in the oral cavity.

In addition, the support layer 20 is a layer to which the light L irradiated to the patch 1 reaches the light absorbing layer 40 before reaching the light absorbing layer 40 , and has a refractive index higher than the refractive index of the light absorbing layer 40 . contains large polymers.

In addition, the support layer 20 and the light absorbing layer 40 may be in a form in which one surface is in contact with the upper and lower phases, and an additional polymer layer may be included between the support layer 20 and the light absorbing layer 40 . If the light L irradiated to the patch is irradiated to the support layer 20 before reaching the light absorbing layer 40, it is not particularly limited.

Preferably, the support layer 20 includes a polymer having a larger refractive index than that of the polymer used for the light absorption layer 40, but is not limited thereto, for example, polyethylene (PE), ethyl cellulose (EC), polymethylmethacrylic rate (PMMA), polyvinyl acetate (PVAc), methacryloylethylbetaine/methacrylate copolymer (Yukaformer), methacrylic acid copolymer, polyester, polyurethane, cellulose acetate phthalate, cellulose acetate succinate, polyvinyl acetate phthalate, shellac alone, or a mixture thereof.

More preferably, when the light absorption layer 40 includes ethyl cellulose (EC), the support layer 20 may include polyethylene (PE) for the purpose of the present invention to achieve an excellent whitening effect.

The adhesive layer 10 is a layer including a whitening active ingredient, and means a layer on which one surface is attached to the teeth. The adhesive layer 10 includes a hydrophilic polymer because it must have a property of being hydrated by water in order to be attached to the teeth. ), polyalkyl vinyl ether-maleic acid copolymer (PVM/MA copolymer: Gantrez AN 119, AN 139, S 97), polyvinyl alcohol, polyacrylic acid, poloxamer 407 (Pluronic, poly(ethylene oxide)-poly(propylene oxide) )-poly(ethylene oxide) triblock copolymer), polyethylene oxide, polyvinylpyrrolidone-vinyl acetate copolymer, polyquaternium-11, polyquaternium-39, carboxypolymethylene, gelatin, alginic acid alone or a mixture thereof and preferably polyvinylpyrrolidone, and/or polyalkyl vinyl ether-maleic acid copolymer.

The adhesive layer 10 includes a whitening active ingredient, and the whitening active ingredient is not particularly limited as long as it is a whitening active ingredient used in a tooth whitening patch, but preferably a component that can be activated by light irradiated to the patch These include, for example, hydrogen peroxide, urea peroxide, calcium peroxide, sodium pyrophosphate, or mixtures thereof.

Preferably, the present invention relates to the above (b) multi-layered tooth whitening patch having an absorbance of 1 to 1.5 abs at a wavelength of 380-540 nm, more preferably an absorbance of 1 to 1.3 abs at a wavelength of 400-520 nm. It provides a tooth whitening device comprising:

The absorbance can be measured by an absorbance measurement method commonly used in the art. For example, the present inventors attached the patch 1 cut to 1 * 3 cm to one side of a quartz cuvette commonly used for absorbance measurement. , JASCO, Inc., the absorbance was measured using a V-670 spectrophotometer.

In addition, the present invention includes a support layer 20, an adhesive layer 10 and a light absorbing layer 40, wherein the light absorbing layer 40 is laminated between the support layer 20 and the adhesive layer 10, a multilayer structure It provides a patch (1) for teeth whitening.

The present invention provides a tooth whitening patch in which the light absorption layer 40 increases the absorbance of the patch 1 .

In the context of the present invention, "increasing" the absorbance of the patch means that the absorbance of the patch according to the present invention is compared with the absorbance of a conventional tooth whitening patch or a tooth whitening patch that does not include the light absorption layer disclosed in the present invention. Used in the sense of indicating “greater,” “improved,” or “increased.”

In particular, the present invention provides a tooth whitening patch (1) in which light (L) irradiated for tooth whitening forms an additional refraction in the patch at least once in addition to the interface between the patch and air.

In addition, the patch 1 provides a tooth whitening patch that may further include one or more polymer layers having a refractive index different from that of the light absorption layer 40 .

In the present invention, when the refractive index of the light absorbing layer 40 is n1 and the refractive index of the support layer 20 is expressed as n2, a tooth whitening patch (1) comprising a light absorbing layer 40 with n1/n2 < 1 to provide. The n1/n2 may be calculated according to a well-known Snell's law.

As shown in FIG. 1, the light absorption layer 40 that increases the absorbance of the patch 1 may include a polymer having a low refractive index, and thus the patch 1 by increasing the path of light passing through the patch ( 1) can increase the absorbance.

In one embodiment, the present inventors found that the light irradiated to the tooth whitening patch including the light absorbing layer 40 and satisfying n1/n2 < 1 is compared with the light irradiated to the patch not including the light absorbing layer, the adhesive layer It was confirmed that the passage of light in the light absorbing layer increased before reaching the light absorbing layer, resulting in an increase in the absorbance of the patch. Accordingly, it was confirmed that the present invention effectively transmits light energy to the whitening active ingredient to increase the tooth whitening effect.

As confirmed in one embodiment, the mechanism of 'increasing the passage of light' by the light absorbing layer 40 of the present invention is to explain the 'absorbance increase' effect of the patch disclosed in the present invention. It is not intended to limit the mechanism.

The light absorption layer 40 may include a polymer having a low refractive index, for example, ethyl cellulose (EC), hydroxypropyl cellulose (HPC), polyvinyl alcohol (PVA), carboxymethyl cellulose (CMC) or a mixture thereof. It may include, preferably carboxymethyl cellulose or ethyl cellulose. Most preferably, for the purpose of the present invention, a polymer having a refractive index smaller than that of the polymer included in the support layer 20 is included.

The support layer 20 includes a polymer having a larger refractive index than that of the polymer used for the light absorption layer 40, but is not limited thereto, for example, polyethylene (PE), ethyl cellulose (EC), polymethyl methacrylate (PMMA) , polyvinyl acetate (PVAc), methacryloylethylbetaine/methacrylate copolymer (Yukaformer), methacrylic acid copolymer, polyester, polyurethane, cellulose acetate phthalate, cellulose acetate succinate, polyvinyl acetate phthalate , shellac alone or a mixture thereof.

More preferably, when the light absorption layer 40 includes ethyl cellulose (EC), the support layer 20 may include polyethylene (PE).

In addition, the tooth whitening patch 1 of the present invention further includes an adhesive layer 10 containing a whitening active ingredient.

The whitening active ingredient is not particularly limited as long as it is a component commonly used in a tooth whitening patch, but preferably a peroxide that can be activated by light is used, for example, hydrogen peroxide, urea peroxide, calcium peroxide, sodium pyrophosphate. or a mixture thereof.

The adhesive layer 10 includes a hydrophilic polymer that can be hydrated by water so that it can be attached to teeth, and the hydrophilic polymer is preferably polyvinylpyrrolidone (PVP), polyalkyl vinyl ether-maleic acid copolymer ( PVM/MA copolymer: Gantrez AN 119, AN 139, S 97), polyvinyl alcohol, polyacrylic acid, poloxamer 407 (Pluronic, poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymer), Polyethylene oxide, polyvinylpyrrolidone-vinylacetate copolymer, polyquaternium-11, polyquaternium-39, carboxypolymethylene, gelatin, alginic acid alone or a mixture thereof may be included, preferably polyvinylpi rolidone, and/or polyalkyl vinyl ether-maleic acid copolymers. As the solvent for these polymers, mainly water, ethanol alone or a mixture thereof, and other organic solvents such as ethyl acetate, ethylene chloride or a mixture thereof may be used.

In addition, the present invention provides a tooth whitening patch (1) having a thickness of 200 to 400 μm. Preferably, it is 230 to 370 μm, more preferably 250 to 350 μm, even more preferably 275 to 325 μm, and most preferably 300 μm. In addition, the thickness of the light absorbing layer 40 included in the patch 1 of the present invention may be 10 to 300 μm. Preferably, it is 30-250 micrometers, More preferably, it is 50-150 micrometers. When the thickness of the patch 1 according to the present invention is 200 to 400 μm, it is possible to provide a patch having a desired absorbance, thereby providing a tooth whitening patch that efficiently activates a whitening component.

In addition, the absorbance of the patch 1 according to the present invention is preferably 1 to 1.5 abs at a wavelength of 380-540 nm, more preferably 1 to 1.3 abs at a wavelength of 400-520 nm.

In one embodiment, the present inventors cut the patch according to the present invention to 1*3 cm, attach it to one side of a quartz cuvette, and measure the absorbance using a UV/VIS spectrophotometer (JASCO, V-670) It was confirmed that the whitening effect was improved when the absorbance at a wavelength of 380-540 nm was 1 to 1.5 abs.

The polymer layer included in the light-irradiated tooth whitening patch according to the present invention, for example, the support layer 20, the light absorption layer 40 or the adhesive layer 10, contains a plasticizer to flexibly bend the patch along the curved surface of the tooth. may include more. The plasticizer is not particularly limited as long as it is used in the art, but for example, polypropylene glycol, glycerin, or polyethylene glycol, castor oil, hydrogenated castor oil, or a mixture thereof may be used.

The adhesive layer 10 of the tooth whitening patch 1 according to the present invention may further include a stabilizer, for example, a peroxide stabilizer to improve stability of the whitening active ingredient. The peroxide stabilizer is not particularly limited as long as it is used in the art, for example, sodium pyrophosphate, sodium acid pyrophosphate, sodium metaphosphate, sodium polyphosphate, condensed phosphate (polyphosphate) such as sodium pyrophosphate; A metal-chelating agent such as ethylenediaminetetraacetate, aminotrimethylenephosphate, hydroxyethylenediphosphonate, ethylenediaminetetramethylenephosphonate, diethylenetriaminepentamethylenephosphonate and salts thereof may be used. .

The adhesive layer 10 of the tooth whitening patch 1 according to the present invention may further include a bleaching activator to assist the whitening active ingredient, and may further include a fragrance to improve the feeling of use when applied to teeth. , may further include an oral health agent to additionally exhibit effects such as antibacterial, anti-inflammatory, and bad breath removal other than teeth whitening. The components that may be further included are not particularly limited as long as they can be used in the art within a range that does not impair the purpose of the present invention.

In addition, the present invention provides a tooth whitening patch further comprising at least one polymer layer having a different refractive index from the light absorbing layer 40 .

In addition, the present invention provides a tooth whitening patch (1) further comprising an exfoliation layer (30) and the like to be removed before tooth attachment.

In addition, the present invention is i) a support layer 20; Adhesive layer 10 containing a tooth whitening active ingredient; and a patch attachment step of attaching a multi-layered tooth whitening patch (1) including a light absorbing layer (40) laminated between the support layer (20) and the adhesive layer (10) to the teeth; And ii) provides a method of whitening teeth comprising a light irradiation step of irradiating light (L) to the patch attached to the tooth.

The multi-layered tooth whitening patch used in the patch attaching step may use the multi-layered tooth whitening patch 1 described above.

The light irradiated in the light irradiation step is light (L) irradiated to activate the whitening active ingredient included in the patch, preferably light having a wavelength of 380-540 nm, more preferably a wavelength of 400-520 nm irradiate light with

The present invention may provide a tooth whitening patch in which irradiated light can efficiently activate a whitening active ingredient in a method of whitening teeth using a light irradiation method.

In particular, the absorbance of the patch with respect to the irradiated light is improved, so that the activity of the whitening active ingredients is improved, and thus, it is possible to provide an improved whitening effect without increasing the concentration of the whitening active ingredients, for example, peroxide.

The present invention can provide a method for whitening teeth using the patch described above.

In addition, the present invention is the above-mentioned patch; And it is possible to provide a tooth whitening device including a light irradiation device, in particular, it is possible to provide a simple tooth whitening device that is convenient to carry.

The following drawings attached to this specification illustrate preferred embodiments of the present invention, and serve to further understand the technical spirit of the present invention together with the above-described content of the invention, so the present invention is limited to the matters described in those drawings It should not be construed as being limited.
FIG. 1 illustrates the refraction of light when light L is irradiated to a patch 1 having a multilayer structure that does not include a light absorbing layer.
2 is a diagram illustrating the refraction of light when light L is irradiated to the patch 1 having a multilayer structure including the light absorbing layer 40 as in the present invention. Compared with FIG. 1 , it can be seen that the irradiated light L is refracted in the patch 1 , and the path of the light increases.
The light refraction aspect shown in the drawings is only an example for explaining the difference in refractive index between the support layer 20 and the light absorption layer 40, and the refractive index and the like are not limited to the aspects shown in the drawings.

Hereinafter, examples and the like will be described in detail to help the understanding of the present invention. However, the embodiments according to the present invention may be modified in various other forms, and the scope of the present invention should not be construed as being limited to the following examples. The embodiments of the present invention are provided to more completely explain the present invention to those of ordinary skill in the art to which the present invention pertains.

In order to measure the absorbance of the tooth whitening patch and compare the whitening effect, Examples 1-8 and Comparative Examples 1-2 were prepared with the configuration shown in Table 1.

Preparation of Examples 1-8

Prepare a solution having the composition shown in Table 1 below, dry the adhesive layer, apply/dry to a thickness of 100 μm, and apply/dry the light absorbing layer to a thickness of 100 μm in the same manner to obtain a total thickness of 200 μm after drying. did Then, it was matched with the PE film as a support layer.

Preparation of Comparative Example 1-2

A solution having the composition shown in Table 1 was prepared, and the adhesive layer was dried and then applied/dried to a thickness of 200 μm. Then, it was matched with the PE film as a support layer.

(weight%) comparative example Example One 2 One 2 3 4 5 6 7 8 support layer Poly Ethylene Film Poly Ethylene Film Poly Ethylene Film Poly Ethylene Film Poly Ethylene Film Poly Ethylene Film Poly Ethylene Film Poly Ethylene Film Poly Ethylene Film Poly Ethylene Film light absorption layer EC - - 24.1 - - - 24.1 - - - HPC - 29.1 - - - 29.1 - - PVA - - 20.8 - - - 20.8 - CMC - - - 12.2 - - - 12.2 Sorbitan oleate 5 5.9 3.3 3.3 5 5.9 3.3 3.3 Glycerin 4.3 4.3 10.2 10.2 4.3 4.3 10.2 10.2 Caster oil 11.1 9.7 - - 11.1 9.7 - - Ethanol To 100 To 100 - - To 100 To 100 - - Water - - To 100 To 100 - - To 100 To 100 adhesive layer Hydrogen peroxide 3 3 3 3 3 3 3 3 3 3 PVP 27.4 - 27.4 27.4 27.4 27.4 - - - - Gantrez - 29.1 - - - - 29.1 27.4 27.4 27.4 Sorbitan oleate 6.3 7 6 6 3 3 7 6 6 6 Glycerin 9.6 9.6 5 5 8 8 9.6 5 5 5 Water To 100 To 100 To 100 To 100 To 100 To 100 To 100 To 100 To 100 To 100

The support layers of Comparative Examples 1-2 and 1-8 were prepared to include polyethylene, the adhesive layer of Examples 1-4 was polyvinylpyrrolidone, and the adhesive layer of Examples 5-8 was polyalkylvinyl ether-maleic acid. The coalescence (Gantrez S 97) was used. The light absorbing layer used different polymers in Examples 1-8, and the refractive index was adjusted differently, and Comparative Example 1-2 was prepared not to include the light absorbing layer. Both Examples 1-8 and Comparative Example 1-2 were prepared to have a total thickness of 300 μm.

Absorbance measurement experiment of patch

After cutting the patches of Examples and Comparative Examples to 1 * 3 cm, and attaching them to one side of a quartz cuvette, the absorbance at a wavelength of 400-520 nm was measured using a UV-Vis spectrum (JASCO, V-670 Spectrophotometer). The measured absorbance is shown in Table 2.

Measured absorbance (abs) Example 1 1.25 Example 2 1.27 Example 3 1.24 Example 4 1.30 Example 5 1.16 Example 6 1.20 Example 7 1.16 Example 8 1.20 Comparative Example 1 0.60 Comparative Example 2 0.80

Whitening effect comparison experiment

1. Preparation of colored hydroxyapatite (HAP) tablet specimens

A tablet with a diameter of 12.5 mm and a thickness of 1.8 mm was prepared by applying a pressure of 4.2 tons of hydroxyapatite powder with an IR press, and then sintered at 1,000 °C and molded with an epoxy resin to synthesize a resin. Thereafter, after etching the surface with strong acid, a TSB (trypticase soybroth) solution in which tea, coffee, iron, and mucin were dissolved, and an automatic stainer rotating at 0.5 RPM to contaminate the specimen prepared for 8 hours a day for 1 week made it Thereafter, the specimen was lightly washed with a toothbrush in running water to remove contaminants that were dissolved or easily removed by water, and then dried at room temperature.

2. Evaluation of whitening effect

The initial brightness value of the colored hydroxyapatite tablet specimen was measured with a colorimeter (Minolta, CR-321), a tooth whitening patch was attached to the specimen soaked in water, and 0.1 W/ It was irradiated at intervals of 12 mm with an intensity of cm ² . After 20 minutes, the patch was removed, rubbed lightly in running water with a toothbrush, dried at room temperature, and then the brightness was measured again. The difference in brightness (ΔE) before and after light irradiation using the patch was calculated. The calculated differences in brightness are shown in Table 3.

Whitening effect (ΔE) Example 1 23.07 ± 1.10 Example 2 23.61 ± 1.25 Example 3 22.40 ± 0.80 Example 4 24.22 ± 1.00 Example 5 21.25 ± 1.02 Example 6 21.74 ± 1.48 Example 7 21.27 ± 0.63 Example 8 22.39 ± 1.12 Comparative Example 1 17.35 ± 1.16 Comparative Example 2 18.78 ± 0.70

result

As can be seen in Table 2, the patches of Examples 1-8 and Comparative Examples 1-2 had the same thickness and were irradiated with light from the same light source, but it was confirmed that the absorbance of the patches was different. Specifically, it was confirmed that the absorbance of Examples 1-8 to which the present invention was applied increased.

In addition, as can be seen in Table 3, it was confirmed that the difference in the brightness values before and after the whitening treatment of Examples 1-8 was greater than the difference between the brightness values before and after the whitening treatment of Comparative Examples 1-2. In particular, when comparing Comparative Example 1 and Example 4, it was confirmed that Example 4 increased by about 40% in the value of the difference in brightness.

Accordingly, it was found that the tooth whitening effect of the tooth whitening patch including the light absorbing layer of the present invention was excellent.

1 - Multi-layered patch
10 - adhesive layer
20 - support layer
30 - release layer
40 - light absorption layer
L - irradiated light

Claims (19)

(a) a light irradiation device for irradiating light for teeth whitening, and
(b) a tooth whitening device comprising a multi-layered tooth whitening patch,
The (b) multi-layered tooth whitening patch (1) is
support layer 20;
Adhesive layer 10 containing a whitening active ingredient; and
and a light absorption layer 40 laminated between the support layer 20 and the adhesive layer 10,
The support layer includes a water-insoluble polymer, and the water-insoluble polymer is polyethylene (PE), ethyl cellulose (EC), methacryloylethylbetaine/methacrylate copolymer (Yukaformer), methacrylic acid copolymer, poly ester, polyurethane, cellulose acetate phthalate, cellulose acetate succinate, polyvinyl acetate phthalate alone or mixtures thereof;
The light absorption layer includes a polymer that is ethyl cellulose (EC), hydroxypropyl cellulose (HPC), polyvinyl alcohol (PVA), carboxymethyl cellulose (CMC), or a mixture thereof,
The (b) tooth whitening device, characterized in that the absorbance of the multi-layered tooth whitening patch is 1 to 1.5 abs at a wavelength of 380-540 nm. According to claim 1, wherein (a) the light irradiation device is a tooth whitening device, characterized in that it comprises any one or more selected from the group consisting of an LED element, a laser, and a UV lamp. The tooth whitening device according to claim 1, wherein the (a) light irradiation device irradiates light having a wavelength of 380 to 540 nm. The tooth whitening device according to claim 1, further comprising (c) an opening device. delete delete In the multi-layered tooth whitening patch,
support layer 20;
Adhesive layer 10 containing a whitening active ingredient; and
and a light absorption layer 40 laminated between the support layer 20 and the adhesive layer 10,
The support layer includes a water-insoluble polymer, and the water-insoluble polymer is ethyl cellulose (EC), methacryloylethylbetaine/methacrylate copolymer (Yukaformer), methacrylic acid copolymer, polyester, polyurethane, Cellulose acetate phthalate, cellulose acetate succinate, polyvinyl acetate phthalate alone or a mixture thereof,
The light absorption layer includes a polymer that is ethyl cellulose (EC), hydroxypropyl cellulose (HPC), polyvinyl alcohol (PVA), carboxymethyl cellulose (CMC), or a mixture thereof,
The absorbance of the multi-layered tooth whitening patch is 1 to 1.5 abs at a wavelength of 380-540 nm. The tooth whitening patch according to claim 7, wherein when the refractive index of the light absorbing layer is expressed as n1 and the refractive index of the support layer is expressed as n2, n1/n2 <1. delete delete delete The tooth whitening patch according to claim 7, wherein the whitening active ingredient comprises hydrogen peroxide, urea peroxide, calcium peroxide, sodium pyrophosphate, or a mixture thereof. The tooth whitening patch according to claim 7, wherein the adhesive layer further comprises at least one selected from the group consisting of a plasticizer, a peroxide stabilizer, a bleaching activator, a fragrance, and an oral health agent. The tooth whitening patch according to claim 7, wherein the patch has a thickness of 200 to 400 μm. The tooth whitening patch according to claim 7, wherein the light absorbing layer has a thickness of 10 to 300 μm. delete The tooth whitening patch according to claim 7, wherein the patch further comprises at least one polymer layer having a refractive index different from that of the light absorbing layer. i) a patch attachment step of attaching the tooth whitening patch according to claim 7 to the teeth; and
ii) a method of whitening teeth comprising the step of irradiating light to the patch attached to the tooth. The method of claim 18, wherein the light irradiated in the step ii) light irradiation is light of a wavelength of 380-540 nm.

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