KR102390010B1 - Anti-irritant cosmetic composition containing guar gum derivative - Google Patents

Abstract

The present invention relates to a hypoallergenic cosmetic composition using a polymer derived from guar gum. According to the present invention, a polymer derived from guar gum, which is a nature-friendly component, is applied without using an emulsifier, so there is no skin irritation and excellent formulation stability. It is expected that it will be able to provide a polar cosmetic composition, so that it can be used universally and usefully for basic cosmetics based on various formulations.

Description

Hypoallergenic cosmetic composition using a polymer derived from guar gum {ANTI-IRRITANT COSMETIC COMPOSITION CONTAINING GUAR GUM DERIVATIVE}

The present invention relates to a hypoallergenic cosmetic composition using a polymer derived from guar gum, and to a cosmetic composition having excellent stability and feeling of use without skin irritation by applying a polymer derived from guar gum without the use of an emulsifier commonly used.

The skin is the outermost part of the body and is an important organ that protects the body from the outside. The skin protects the body from physical, chemical, and external stimuli, and also functions to suppress the loss of moisture from the body. A certain amount of moisture, natural moisturizing factor (NMF), and sebum components exist in the skin, and it helps the skin to perform moisturizing and protective functions on its own, and keeps the skin healthy. However, the skin may have limitations in performing a normal function by itself due to external environmental factors, that is, excessive washing of the skin or drying, ultraviolet rays, pollution, and the like. This limitation can be solved by using basic cosmetics, and it can help the skin to perform its normal function.

Basic cosmetics can be prepared using conventional emulsion, that is, emulsification technology. Emulsification refers to a system in which two immiscible phases, such as water and oil, are dispersed in one phase in a fine particle state using a type of surfactant called an emulsifier. In other words, basic cosmetics that want to help perform the skin's original function include water corresponding to the skin's moisture and water-soluble moisturizers corresponding to the natural moisturizing factor, as well as oily components corresponding to the sebum component (e.g., oil, wax, etc.) includes However, emulsifiers usually cause irritation to the skin or promote penetration of irritating substances contained in cosmetics, for example, substances such as preservatives, so that they have a bad effect on the skin or the human body. Nonionic surfactants that are less irritating to the human body are used in the cream. However, nonionic surfactants may also act as a cause of irritation in sensitive skin, so there is still a need to develop a raw material or formulation that can replace it.

To date, many studies have been conducted to solve the skin irritation problem, but most of them use surfactants with low irritation or compounds having structural characteristics similar to surfactants. As an example, Patent Document 1 discloses a silicone underwater cosmetic composition using lecithin, a natural material. However, since lecithin is also a type of surfactant, it is difficult to exclude skin irritation. Long-term storage of the prepared emulsion is a problem. As another example, Patent Document 2 discloses a cosmetic composition that does not contain an emulsifier. However, in this case, since it relates to a two-phase composition in which the aqueous phase component and the oil phase component are not mixed with each other and are separated, it is not only cumbersome to use, but also the feeling of use is not good.

In addition, as a method for solving the problem of skin irritation, the use of an irritant alleviating raw material may be mentioned. Currently, such an irritant-relieving raw material includes non-steroidal compounds such as flufenamic acid, ibuprofen, benzydamine and indomethacin; and steroid-based compounds such as prednisolone and dexamethasone; and the like. However, most of these irritation-relieving raw materials have problems in terms of safety for the skin or stability at the time of formulation of the composition, and thus their use is limited. Therefore, it is necessary to develop raw materials and formulations that have few side effects to the human body and have a stimulating effect.

KR 10-2002-0037205 A KR 10-2001-0017428 A

An object of the present invention is to provide a hypoallergenic cosmetic composition that can exclude skin irritation caused by emulsifiers with a surfactant-free system, has excellent skin safety, and provides improved formulation stability and feeling of use.

In detail, the present invention is to provide an oil-in-water emulsion hypoallergenic cosmetic composition having excellent formulation stability at the time of formulation without using an emulsifier.

Specifically, the present invention is to provide an oil-in-water emulsion hypoallergenic cosmetic composition without skin irritation suitable for sensitive skin.

For the above-mentioned purpose, the present invention may comprise the following means.

An oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention comprises: an aqueous phase comprising hydroxypropyl guar hydroxypropyltrimonium chloride, xanthan gum and C4-C10 monoacyl-substituted glycerol; and an oil phase comprising C14-C22 monoacyl or diacyl substituted glycerol; may contain.

In the oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention, the weight ratio of hydroxypropyl guar hydroxypropyltrimonium chloride and xanthan gum may be 4:1 to 40:1.

In the oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention, the weight ratio of the C4-C10 monoacyl-substituted glycerol to the C14-C22 monoacyl or diacyl-substituted glycerol may be 1:1 to 1:10. .

In the oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention, the C14-C22 monoacyl or diacyl substituted glycerol may be a C16-C20 monoacyl substituted glycerol.

In the oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention, the oil phase further includes oil, and the cosmetic composition may include 5 to 30% by weight of the oil based on the total weight. there is.

In the oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention, the cosmetic composition may be substantially free of one or two or more selected from polyethylene oxide-based surfactants and sorbitan-based surfactants.

In the oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention, the stability of the cosmetic composition may satisfy Relational Expression 1 below.

[Relational Expression 1]

1.0 ≤ D ₂ /D ₁ ≤ 2.0

[In the above relation 1,

D ₁ is the average particle diameter of the initial dispersion particles,

D ₂ is the average particle diameter of the dispersion particles after 100 days under the condition of 20°C, and the polydispersity of the dispersion particles is 0.12 or less.]

The oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention is selected from silk grass, mountain seaweed, lotus root meat, bird sand vine, oriental herb, Yeongyo, honeysuckle, jimo, seokjampul, gilgyeong, pine needles, burdock root, and seokchangpo. It may further include one or more herbal extracts.

In the oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention, the cosmetic composition may be hypoallergenic to sensitive, atopic or trouble skin.

The oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention may be in the form of skin, lotion, essence, cream, pack, makeup base, foundation, sun cream, sun lotion or sun milk.

According to the present invention, it is possible to provide a hypoallergenic cosmetic composition having excellent formulation stability without skin irritation by applying a polymer derived from guar gum, which is a natural component, without using an emulsifier. Specifically, according to the present invention, since the emulsifier conventionally used in the emulsification formulation is not substantially used, skin irritation is completely excluded and, at the same time, the formulation stability according to the change over time is increased to prevent floating or separation of oily components such as oil. does not cause

According to the present invention, it has the advantage of being able to provide a hypoallergenic cosmetic composition of an oil-in-water emulsion formulation that is light in use and can simultaneously impart a feeling of softness and moisture to the skin.

In short, according to the present invention, by providing a hypoallergenic cosmetic composition of an oil-in-water emulsion formulation having excellent formulation stability without skin irritation by an emulsifier, the limitations of the prior art are overcome, and an oily component without a complicated combination of emulsifiers or additional energy consumption can be effectively stabilized. In addition, it is expected that it can be used universally and usefully for basic cosmetics based on various formulations because it can give excellent satisfaction when used with a fresh application without a sticky or heavy oily feeling.

The hypoallergenic cosmetic composition using the guar gum-derived polymer according to the present invention will be described in detail below, but unless otherwise defined in the technical and scientific terms used at this time, those of ordinary skill in the art to which this invention belongs has the meaning understood as , and descriptions of well-known functions and configurations that may unnecessarily obscure the gist of the present invention in the following description will be omitted.

As used herein, the term "acyl" is a substituent induced by removal of OH, which is a carboxyl group of carboxylic acid, and may be represented by R(C=O)-* in general formula (wherein R is an alkyl group). For example, monoacyl-substituted glycerol refers to glycerol mono-substituted with an acyl group containing one alkyl group, and diacyl-substituted glycerol refers to glycerol di-substituted with an acyl group containing one alkyl group.

As used herein, the term "stability" encompasses the stability of the initial formulation of the composition, the stability of the formulation according to long-term storage, and the like, and in the present specification, the particle size change of the dispersion particles for the composition, the polydispersity of the dispersion particles ( Polydispersity index, PDI) change, etc., as well as evaluation by changes in the appearance of the composition is absent or insignificant, meaning both to stably maintain the state of the initial formulation.

As used herein, the term "substantially free of" means that other raw materials, materials, or configurations not listed together with the specified raw materials, materials or configurations are not acceptable for at least one basic and novel technical idea of the invention. It means that it can be present in an amount or degree that does not significantly affect it.

As used herein, the term “comprises” is an open-ended substrate having an equivalent meaning to expressions such as “comprises”, “contains”, “has” or “characterizes”, and raw materials not listed further , materials or configurations are not excluded.

Also, the singular form used herein may be intended to include the plural form as well, unless the context specifically dictates otherwise.

In addition, in the present specification, the unit used without special mention is based on the weight, for example, the unit of % or ratio means weight % or weight ratio, and the weight % means any one component of the entire composition unless otherwise defined. It means the weight % occupied in the composition.

In addition, the numerical range used herein includes the lower limit and upper limit and all values within the range, increments logically derived from the form and width of the defined range, all values defined therein, and the upper limit of the numerical range defined in different forms. and all possible combinations of lower limits. Unless otherwise defined in the specification of the present invention, values outside the numerical range that may occur due to experimental errors or rounding of values are also included in the defined numerical range.

While the present inventors were intensifying research on raw materials and formulations that can exclude irritation to emulsifiers commonly used in basic cosmetics that help the skin's natural function, hydroxypropyl guar hydroxypropyltri, a polymer derived from guar gum, Based on the structural characteristics of monium chloride and xanthan gum, it was confirmed that an oil-in-water emulsion formulation could be provided, and a composition capable of forming a formulation capable of securing formulation stability over time without an emulsifier was found.

Specifically, according to the present invention, hydroxypropyl guar hydroxypropyltrimonium chloride, which is a cationic guar gum-derived polymer having the following structure, can be chemically bonded to xanthan gum and combined with acyl-substituted glycerol contained in the aqueous and oil phases. Accordingly, it is possible to realize a stable oil-in-water (O/W) formulation without emulsifiers such as polyethylene oxide-based surfactants commonly used in basic cosmetics, and at the same time provide advantages in long-term storage. Accordingly, the present inventors intend to propose the present invention to provide a formulation of a new aspect that can completely exclude skin irritation caused by emulsifiers without adverse effects on the human body.

Moreover, according to the present invention, it is possible to implement a stable formulation by forming a nano-level dispersion even in a formulation without using an emulsifier, and its change is minimized, indicating excellent formulation stability according to time change. That is, according to the present invention, floating or separation of oily components such as oil does not occur.

In addition, according to the present invention, it has the advantage of being able to stably disperse the oil phase component without an emulsifier, as well as providing the benefits of feeling of use of the oil-in-water emulsion.

The oil-in-water emulsion hypoallergenic cosmetic composition according to the present invention, which can implement such an effect, includes an aqueous phase comprising hydroxypropyl guar hydroxypropyltrimonium chloride, xanthan gum and hydrophilic monoacyl-substituted glycerol; and an oil phase comprising a lipophilic monoacyl or diacyl substituted glycerol; It may be prepared through emulsification technology using

Hereinafter, the configuration of the present invention will be described in detail.

An oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention comprises: an aqueous phase comprising hydroxypropyl guar hydroxypropyltrimonium chloride, xanthan gum and C4-C10 monoacyl-substituted glycerol; and an oil phase comprising C14-C22 monoacyl or diacyl substituted glycerol; may contain.

In the oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention, the hydroxypropyl guar hydroxypropyltrimonium chloride has an appropriate level of ionization required for chemical bonding with xanthan gum in terms of stability during composition formulation. have Accordingly, it is expected that improved stability can be realized by organically acting ionic bonds, hydrogen bonds, van der Waals bonds, and the like when compounding the composition.

In terms of this effect, the oil-in-water emulsion hypoallergenic cosmetic composition may include hydroxypropyl guar hydroxypropyltrimonium chloride and xanthan gum in a weight ratio of 4:1 to 40:1. Specifically, the weight ratio may include to satisfy a weight ratio of 5:1 to 35:1, and more specifically, may include it to satisfy a weight ratio of 5:1 to 30:1.

The oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention satisfies the above weight ratio, but contains 0.1 to 5% by weight of hydroxypropyl guar hydroxypropyltrimonium chloride and C4 based on the total weight of the cosmetic composition It may contain an aqueous phase comprising -C10 monoacyl-substituted glycerol in an amount of 0.01 to 3% by weight. In addition, the oil-in-water emulsion hypoallergenic cosmetic composition may contain 0.1 to 3% by weight of the C4-C10 monoacyl substituted glycerol, preferably 0.5 to 2% by weight.

In addition, in the oil-in-water emulsion hypoallergenic cosmetic composition, the C4-C10 monoacyl substituted glycerol and the C14-C22 monoacyl or diacyl substituted glycerol are 1:1 to It may be included to satisfy a weight ratio of 1:10. Specifically, the weight ratio may include to satisfy a weight ratio of 1:1 to 1:8, more specifically, it may include to satisfy a weight ratio of 1:1 to 1:5, and most specifically 1: It may be included to satisfy a weight ratio of 1 to 1:3.

In the oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention, the monoacyl-substituted glycerol contained in the aqueous phase is in order to have solubility in water, in monoacyl-substituted glycerol containing an alkyl group having 4 to 10 carbon atoms. One or two or more selected may be used, and specifically, it is preferable to include monoacyl-substituted glycerol containing an alkyl group having 6 to 8 carbon atoms.

For example, the aqueous phase may include glyceryl hexanoate, glyceryl caprylate, or a combination thereof.

In the oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention, the monoacyl or diacyl-substituted glycerol contained in the oil phase is monoacyl-substituted glycerol or diacyl-substituted glycerol containing an alkyl group having 14 to 22 carbon atoms. It can be used, and specifically, it is preferable to include an alkyl group having 16 to 20 carbon atoms.

For example, the oil phase may include C16-C20 monoacyl substituted glycerol.

For example, the oil phase may include glyceryl palmitate, glyceryl stearate, or a combination thereof.

As described above, the oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention does not use an emulsifier, so there is no skin irritation caused by the emulsifier. In addition, despite the formulation that does not use an emulsifier, it has the characteristic of being able to stably provide an oil-in-water emulsion with excellent feel. Specifically, the oil-in-water emulsion hypoallergenic cosmetic composition according to the present invention does not substantially contain one or more surfactants selected from polyethylene oxide-based surfactants and sorbitan-based surfactants, which are emulsifiers commonly used in oil-in-water emulsions. it may not be Substantially not containing the surfactant may be the case in which the above-described surfactant is included at a concentration of ppb units, that is, an impurity level based on the concentration of the composition.

The oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention can provide advantages in various aspects of use of the oil-in-water emulsion, such as excellent feeling of use as well as quick absorption. In addition, by further including oil as an oily component, it is possible to provide excellent spreadability expressed by softness and the like.

In the oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention, the oil is not limited.

For example, the oil may include hydrocarbon-based oil, ester-based oil, triglyceride-based oil, carbonate-based oil, alcohol-based oil, fluorine-based oil, and silicone-based oil.

For example, the oil may include one or more polar oils selected from alcohol-based oils and triglyceride-based oils having 12 to 25 carbon atoms.

For example, the alcohol-based oil may be a linear or branched chain higher alcohol having 12 to 25 carbon atoms, and non-limiting examples thereof may be selected from cetostearyl alcohol, behenyl alcohol, palmitoyl alcohol, and the like.

For example, the triglyceride-based oil may include a straight-chain or branched fatty acid group having 7 to 25 carbon atoms, and specifically, caprylic/capric/myristic/stearic triglyceride (Caprylic/Capric/Linoleic Triglyceride). ), Caprylic/Capric/Myristic/Stearic Triglyceride, Caprylic/Capric/Succinic Triglyceride, Caprylic /Caprylic/Capric/Stearic Triglyceride, caprylic/capric triglyceride, butylene glycol dicaprylate/caprate and triglycerides It may be one selected from octanoin (trioctanoin) and the like.

For example, the oil may be a mixture of one or more oils selected from the above-described polar oils and one or more oils selected from hydrocarbon-based oils, ester-based oils, carbonate-based oils, fluorine-based oils, and silicone-based oils.

In the oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention, the oil may be included in an amount of 5 to 30% by weight based on the total weight of the cosmetic composition. The oil may be specifically included in an amount of 5 to 25% by weight, more specifically 10 to 20% by weight. In addition, preferably, it may contain the above-mentioned polar oil in an amount of 30% by weight or more based on the above-mentioned content.

When the oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention satisfies the above-described composition, the average particle diameter (D ₁ ) of the initial dispersion particles may be 10 μm or less. In this case, the average particle diameter of the dispersion particles means the average particle diameter (D50) of the spherical emulsified particles present in the oil-in-water emulsion formulation measured using a Zetasizer (Zetasizer 3000Hsa, manufactured by Malvern).

In addition, the oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention may have a stable formulation satisfying the following relational formula (1).

[Relational Expression 1]

1.0 ≤ D ₂ /D ₁ ≤ 2.0

[In the above relation 1,

D ₁ is the average particle diameter of the initial dispersion particles,

D ₂ is the average particle diameter of the dispersion particles after 100 days under the condition of 20°C, and the polydispersity of the dispersion particles is 0.12 or less.]

As an example, the oil-in-water emulsion hypoallergenic cosmetic composition has stability satisfying the above relational formula 1, and the average particle diameter (D ₁ ) of the initial dispersion particles may be less than 10 μm. Specifically, it may be 8 μm or less, and more specifically, it may satisfy 1 to 6 μm.

For example, the stability (D ₂ /D ₁ ) of the oil-in-water emulsion hypoallergenic cosmetic composition may satisfy 1.0 to 1.8.

For example, the stability (D ₂ /D ₁ ) of the oil-in-water emulsion hypoallergenic cosmetic composition may satisfy 1.0 to 1.5.

For example, the oil-in-water emulsion hypoallergenic cosmetic composition may satisfy a stable formulation in which the polydispersity change rate of the dispersion particles is 70% or more after 100 days under 20°C conditions. In this case, as the numerical value of the polydispersity increases, it means that the particle size distribution of the dispersion particles is widely distributed. Accordingly, as the numerical value of the polydispersity decreases, the particle size distribution of the dispersion particles is narrowly distributed, which means that the dispersion particles converge to the average particle diameter to increase the monodispersity.

EMBODIMENT OF THE INVENTION Hereinafter, the specific aspect of this invention is given and demonstrated.

The oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention may be hypoallergenic for sensitive, atopic or troubled skin.

The oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention may be for non-separation of oil capable of stably dispersing the oil phase component.

With these effects, the oil-in-water emulsion hypoallergenic cosmetic composition according to the present invention has few side effects to the human body, has no skin irritation, and has excellent stability and feel, so it can be usefully used as a basic cosmetic to help normal skin protection function. there is.

Specifically, the oil-in-water emulsion hypoallergenic cosmetic composition according to the present invention can provide not only the fresh and light feeling of use unique to the oil-in-water emulsion, but also the flexibility provided by oily components such as oil, so that it can be applied without irritation to sensitive skin. and can be effective.

In addition, the oil-in-water emulsion hypoallergenic cosmetic composition according to the present invention can be combined with various types of irritation-relieving raw materials to impart synergy to skin irritation as well as flexibility to sensitive skin. In addition, it can be combined with a commonly used functional raw material to impart synergy to its effect.

The irritation alleviating raw material and functional raw material may be used without limitation as long as they are conventional, and may be further included in an amount that does not impair the safety of the skin as well as the stability of the formulation.

As an example, one or two or more herbal extracts selected from silkworm, sanhaebaek, lotus root, sandgrass vine, oriental plant, Yeongyo, honeysuckle, ginseng, seokjampu, gilgyeong, pine needles, burdock, and seokchangpo may be mentioned. In this case, the herbal extract may be included in an amount of 0.01 to 10% by weight based on the total weight of the cosmetic composition.

The oil-in-water emulsion hypoallergenic cosmetic composition according to an embodiment of the present invention can not only realize a stable formulation, but also minimize the rate of change over time, and can exhibit effective effects by being formulated with various types of basic cosmetics.

For example, the cosmetic composition according to the present invention may be formulated as a skin, lotion, essence, cream, pack, makeup base, foundation, sun cream, sun lotion or sun milk.

In addition, it goes without saying that the cosmetic composition according to the present invention may further include additional additives in addition to the above-described components as long as the object of the present invention is not impaired. In this case, the additive is not limited as long as it is a conventional component, but for example, a solubilizer, a thickener, an emollient, an antioxidant, a stabilizer, a foaming agent, a fragrance, a filler, a sequestering agent, a chelating agent, a preservative, a vitamin, a skin protectant, a metal sequestering agents, wetting agents, dyes, pigments, and the like, but are not limited thereto. In this case, the additive may be included in an amount of 0.01 to 5% by weight, respectively, based on the total weight of the cosmetic composition.

Hereinafter, a hypoallergenic cosmetic composition using a polymer derived from guar gum according to an embodiment of the present invention will be described in more detail through Examples. However, the following examples are only a reference for describing the present invention in detail, and the present invention is not limited thereto, and may be implemented in various forms.

(Assessment Methods)

1. Skin irritation test

In order to evaluate the skin irritation for each sample (Example and Comparative Example), a patch test was performed on the skin of 20 adult men and women with sensitive skin. Specifically, a certain amount of each sample is added to the pin chamber, attached to the test subject's skin for 24 hours to prevent sample loss using an appropriate size filter paper, then the pin chamber is removed and the skin condition 2 hours later is assessed by two experts. This judging method was used. The evaluation criteria were carried out according to the following, and converted into numerical values according to the following formula (1).

The numerical results are shown in Table 2 below.

(Evaluation standard)

No erythema on the skin at all: (-)

Appears to have erythema on the skin: (±)

Mild erythema on the skin: (+)

Moderate skin erythema: (++)

Strong erythema on the skin: (+++)

(Formula 1)

stimulus =

[(-) number of test subjects x 0 + (±) test subject x 1 + (+) test subject number x 2 + (+++) test subject number x 3 + (+++) test subject Number of test subjects x 4]/ Total number of test subjects

2. Formulation stability evaluation-1

In order to evaluate the formulation stability of each sample (Example and Comparative Example), a change in the average particle diameter of the dispersion particles for each sample was confirmed.

Each sample was stored in a room temperature thermostat (20±2° C.), and the average particle diameter of the dispersion particles was measured at intervals of one week. In addition, the average particle diameter of the dispersion particles was observed for 100 days.

First, the change in the average particle diameter of the dispersion particles for each sample was expressed as a relative value based on the average particle diameter (D ₁ ) of the initial dispersion particles. The angle was fixed at 90 degrees and measurements were made at room temperature (20±2° C.). In addition, the polydispersity (PDI) of the dispersion particles was measured by a cumulative method using a zetasizer. In this case, the smaller the polydispersity value of the dispersion particles, the narrower the particle size distribution.

The values measured by the above-described method and the changes (average particle diameter and polydispersity) of the dispersion particles for each sample calculated therefrom are shown in Table 3 below.

3. Formulation stability evaluation-2

In order to evaluate the formulation stability of each sample (Example and Comparative Example), the formulation stability was determined by observing the emulsification state of each sample.

Each sample consists of a room temperature bath (20±2℃), a refrigeration bath (0±2℃), a high temperature bath 1 (40±2℃), a high temperature bath 2 (50±2℃) and a cycle chamber (Freeze-Thaw Chamber, ( -5 °C -> 25 °C -> 45 °C, cycled at a cycle of 1 day), and visually evaluated at intervals of 1 week for 3 months.

The evaluation criteria were carried out according to the following, and the stability results after 3 months are shown in Table 4 below.

(Evaluation standard)

◎: very good, ○: good, △: slightly unstable, X: very unstable

4. Usability test

In order to evaluate the feeling of use of each sample (Example and Comparative Example), 30 general consumer monitors comprised of women aged 20 to 50 were allowed to use each sample for 1 week, respectively, and then through a double-blind method Satisfaction with the feeling of use was investigated on a 7-point scale.

Evaluation items and their results are shown in Table 5 below.

(Examples 1 to 3 and Comparative Examples 1 to 3)

An oil-in-water emulsion cosmetic composition was prepared through the following method using the compositional components of Table 1 below.

(1) Each component was divided into an aqueous phase and an oil phase, each was heated and dissolved at 75°C and then cooled to 70°C.

(2) The oil phase was put into the aqueous phase and emulsified for 5 minutes at 5,000 rpm using a homomixer. Then, while cooling slowly, other ingredients were added to prepare an oil-in-water emulsion cosmetic composition.

As shown in Table 2, the oil-in-water emulsion cosmetic composition according to the present invention hardly showed any irritation to the skin. Specifically, the oil-in-water emulsion cosmetic composition of all Examples according to the present invention was evaluated as having no erythema on the skin at all, and the evaluation result for the degree of irritation was converted to 0.

On the other hand, it was confirmed that Comparative Example 1 showed a significantly higher degree of stimulation compared to Comparative Examples 1 and 2 as well as the Examples according to the present invention. Accordingly, it was found that polysorbate 60, which is a sorbitan-derived polyethylene oxide-based surfactant, showed a relatively high degree of irritation among nonionic surfactants.

As shown in Tables 3 and 4, it was confirmed that the oil-in-water emulsion cosmetic composition according to the present invention can provide a very good advantage in formulation stability. Specifically, it was found that the oil-in-water emulsion cosmetic composition according to the present invention exhibits excellent high-temperature stability, which is weak in the general oil-in-water emulsion cosmetic composition, despite the formulation without using an emulsifier. In addition, in all examples, it was possible to form a dispersion reaching an average particle diameter of 80 nm or less, and it was confirmed that the change in the average particle diameter of the dispersion particles was insignificant even with time change, and the polydispersity of the dispersion particles was reduced. . That is, it can be confirmed that the oil-in-water emulsion cosmetic composition according to the present invention is a thermodynamically very stable formulation.

As shown in Table 5 above, it was confirmed that the oil-in-water emulsion cosmetic composition according to the present invention had an exceptionally excellent effect on all evaluation items in the usability test for spreadability, absorbency, skin suitability and satisfaction. On the other hand, in the case of Comparative Examples 1 and 2, as stimulation accompanied by erythema was confirmed, it is expected to show disadvantage in the overall evaluation items for the usability test.

As described above, the present invention has been described by specific matters and limited examples, but these are only provided to help a more general understanding of the present invention, and the present invention is not limited to the above examples, and the field to which the present invention belongs Various modifications and variations are possible from these descriptions by those of ordinary skill in the art.

Therefore, the spirit of the present invention should not be limited to the described embodiments, and not only the claims to be described later, but also all those with equivalent or equivalent modifications to the claims will be said to belong to the scope of the spirit of the present invention. .

Claims (10)

an aqueous phase comprising hydroxypropyl guar hydroxypropyltrimonium chloride, xanthan gum and C4-C10 monoacyl substituted glycerol; and
oil phase comprising C14-C22 monoacyl or diacyl substituted glycerol; As an oil-in-water emulsion hypoallergenic skin absorbent cosmetic composition containing,
An oil-in-water emulsion hypoallergenic cosmetic composition that does not contain a polyethylene oxide-based surfactant, a sorbitan-based surfactant, or a combination thereof. The method of claim 1,
The weight ratio of the hydroxypropyl guar hydroxypropyltrimonium chloride and xanthan gum is 4:1 to 40:1, an oil-in-water emulsion hypoallergenic cosmetic composition for skin absorption. The method of claim 1,
The weight ratio of the C4-C10 monoacyl substituted glycerol to the C14-C22 monoacyl or diacyl substituted glycerol is 1:1 to 1:10, oil-in-water emulsion hypoallergenic skin absorbent cosmetic composition. The method of claim 1,
The C14-C22 monoacyl or diacyl substituted glycerol is
C16-C20 monoacyl substituted glycerol, oil-in-water emulsion hypoallergenic skin absorbent cosmetic composition. The method of claim 1,
The oil phase further comprises oil,
The cosmetic composition, based on the total weight, comprising the oil in an amount of 5 to 30% by weight, an oil-in-water emulsion hypoallergenic cosmetic composition for skin absorption. delete The method of claim 1,
The stability of the cosmetic composition is,
An oil-in-water emulsion hypoallergenic skin absorbent cosmetic composition that satisfies the following relation:
[Relational Expression 1]
1.0 ≤ D ₂ /D ₁ ≤ 2.0
[In the above relation 1,
D ₁ is the average particle diameter of the initial dispersion particles,
D ₂ is the average particle diameter of the dispersion particles after 100 days under the condition of 20°C, and the polydispersity of the dispersion particles is 0.12 or less.] The method of claim 1,
Oil-in-water emulsion hypoallergenic skin, further comprising one or more herbal extracts selected from silk grass, mountain seaweed, lotus root meat, bird sand vine, oriental medicine, Yeongyo, honeysuckle, ginseng, seokjampu, gilgyeong, pine needles, burdock, and seokchangpo Absorbent cosmetic composition. The method of claim 1,
The cosmetic composition,
Oil-in-water emulsion hypoallergenic skin absorbent cosmetic composition, characterized in that it is hypoallergenic to sensitive, atopic or trouble skin. The method of claim 1,
The cosmetic composition,
Skin, lotion, essence, cream, pack, makeup base, foundation, sun cream, sun lotion or sun milk formulation, oil-in-water emulsion hypoallergenic skin absorbent cosmetic composition.