KR102388363B1 - 알츠하이머병(ad)의 치료 및 예방 - Google Patents

알츠하이머병(ad)의 치료 및 예방 Download PDF

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Publication number
KR102388363B1
KR102388363B1 KR1020167033332A KR20167033332A KR102388363B1 KR 102388363 B1 KR102388363 B1 KR 102388363B1 KR 1020167033332 A KR1020167033332 A KR 1020167033332A KR 20167033332 A KR20167033332 A KR 20167033332A KR 102388363 B1 KR102388363 B1 KR 102388363B1
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South Korea
Prior art keywords
aluminum oxyhydroxide
patient
administered
aluminum
pharmaceutical composition
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English (en)
Korean (ko)
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KR20160145822A (ko
Inventor
마르쿠스 맨들러
아힘 슈네베르거
아르네 본 보닌
프란크 마트너
발터 슈미트
Original Assignee
어드밴티지 테라퓨틱스, 인코포레이티드
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Publication of KR20160145822A publication Critical patent/KR20160145822A/ko
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Publication of KR102388363B1 publication Critical patent/KR102388363B1/ko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A61K33/08Oxides; Hydroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays or needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020167033332A 2014-04-29 2015-04-29 알츠하이머병(ad)의 치료 및 예방 Active KR102388363B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP14166354.2 2014-04-29
EP14166354 2014-04-29
EP14166355.9 2014-04-29
EP14166355 2014-04-29
PCT/EP2015/059339 WO2015165966A1 (en) 2014-04-29 2015-04-29 Treatment and prevention of alzheimer's disease (ad)

Publications (2)

Publication Number Publication Date
KR20160145822A KR20160145822A (ko) 2016-12-20
KR102388363B1 true KR102388363B1 (ko) 2022-04-19

Family

ID=53039896

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020167033332A Active KR102388363B1 (ko) 2014-04-29 2015-04-29 알츠하이머병(ad)의 치료 및 예방

Country Status (18)

Country Link
US (1) US10478454B2 (https=)
EP (2) EP3137093B1 (https=)
JP (1) JP6692755B2 (https=)
KR (1) KR102388363B1 (https=)
CN (1) CN106659738B (https=)
AU (1) AU2015254663B2 (https=)
CA (1) CA2946928C (https=)
CY (1) CY1119674T1 (https=)
DK (1) DK3137093T3 (https=)
ES (2) ES2824763T3 (https=)
HR (1) HRP20171896T1 (https=)
HU (1) HUE037501T2 (https=)
LT (1) LT3137093T (https=)
NO (1) NO3137093T3 (https=)
PL (1) PL3137093T3 (https=)
PT (1) PT3137093T (https=)
SI (1) SI3137093T1 (https=)
WO (1) WO2015165966A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL3137094T3 (pl) * 2014-04-29 2023-03-13 Advantage Therapeutics, Inc. Leczenie i profilaktyka choroby alzheimera (ad)
EP3137097B1 (en) 2014-04-29 2023-06-21 ADvantage Therapeutics, Inc. Treatment and prevention of alzheimer's disease (ad)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011120924A1 (en) * 2010-03-29 2011-10-06 Novartis Ag Composition comprising the amyloid beta 1-6 peptide coupled to a virus-like particle and an adjuvant

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994016327A1 (en) * 1993-01-14 1994-07-21 Pollard Harvey B Methods and compositions for blocking amyloid protein ion channels
HUP0004331A3 (en) * 1997-08-21 2001-09-28 Gerolymatos P N Sa Use of phanquinone for producing pharmaceutical compositions for the treatment of alzheimer's disease and combined pharmaceutical compositions containing it
TWI239847B (en) * 1997-12-02 2005-09-21 Elan Pharm Inc N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease
PL3137094T3 (pl) * 2014-04-29 2023-03-13 Advantage Therapeutics, Inc. Leczenie i profilaktyka choroby alzheimera (ad)
EP3137097B1 (en) * 2014-04-29 2023-06-21 ADvantage Therapeutics, Inc. Treatment and prevention of alzheimer's disease (ad)

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011120924A1 (en) * 2010-03-29 2011-10-06 Novartis Ag Composition comprising the amyloid beta 1-6 peptide coupled to a virus-like particle and an adjuvant

Also Published As

Publication number Publication date
AU2015254663B2 (en) 2020-04-02
US20170049812A1 (en) 2017-02-23
EP3269376A1 (en) 2018-01-17
EP3137093B1 (en) 2017-09-13
CA2946928C (en) 2023-01-31
CN106659738A (zh) 2017-05-10
EP3137093A1 (en) 2017-03-08
EP3269376B1 (en) 2020-07-15
AU2015254663A1 (en) 2016-11-10
ES2824763T3 (es) 2021-05-13
SI3137093T1 (en) 2018-01-31
CY1119674T1 (el) 2018-04-04
CN106659738B (zh) 2021-02-09
CA2946928A1 (en) 2015-11-05
JP6692755B2 (ja) 2020-05-13
HUE037501T2 (hu) 2018-08-28
HRP20171896T1 (hr) 2018-02-23
PL3137093T3 (pl) 2018-06-29
DK3137093T3 (en) 2017-12-11
US10478454B2 (en) 2019-11-19
LT3137093T (lt) 2017-12-11
KR20160145822A (ko) 2016-12-20
ES2651537T3 (es) 2018-01-29
NO3137093T3 (https=) 2018-02-10
JP2017518275A (ja) 2017-07-06
WO2015165966A1 (en) 2015-11-05
PT3137093T (pt) 2017-12-19

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