KR102277657B9 - 뇌 조직 투명화를 이용한 시냅스 기능 장애 평가 방법 - Google Patents

뇌 조직 투명화를 이용한 시냅스 기능 장애 평가 방법

Info

Publication number
KR102277657B9
KR102277657B9 KR1020190013801A KR20190013801A KR102277657B9 KR 102277657 B9 KR102277657 B9 KR 102277657B9 KR 1020190013801 A KR1020190013801 A KR 1020190013801A KR 20190013801 A KR20190013801 A KR 20190013801A KR 102277657 B9 KR102277657 B9 KR 102277657B9
Authority
KR
South Korea
Prior art keywords
brain tissue
synaptic dysfunction
tissue clearing
evaluating
evaluating synaptic
Prior art date
Application number
KR1020190013801A
Other languages
English (en)
Other versions
KR102277657B1 (ko
KR20200095881A (ko
Inventor
박영일
금상일
Original Assignee
주식회사 바이나리
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 바이나리 filed Critical 주식회사 바이나리
Priority to KR1020190013801A priority Critical patent/KR102277657B1/ko
Priority to PCT/KR2020/001442 priority patent/WO2020159264A1/ko
Publication of KR20200095881A publication Critical patent/KR20200095881A/ko
Application granted granted Critical
Publication of KR102277657B1 publication Critical patent/KR102277657B1/ko
Publication of KR102277657B9 publication Critical patent/KR102277657B9/ko

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076Diagnosing or monitoring particular conditions of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Physiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1020190013801A 2019-02-01 2019-02-01 뇌 조직 투명화를 이용한 시냅스 기능 장애 평가 방법 KR102277657B1 (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1020190013801A KR102277657B1 (ko) 2019-02-01 2019-02-01 뇌 조직 투명화를 이용한 시냅스 기능 장애 평가 방법
PCT/KR2020/001442 WO2020159264A1 (ko) 2019-02-01 2020-01-30 뇌 조직 투명화를 이용한 시냅스 기능 장애 평가 방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020190013801A KR102277657B1 (ko) 2019-02-01 2019-02-01 뇌 조직 투명화를 이용한 시냅스 기능 장애 평가 방법

Publications (3)

Publication Number Publication Date
KR20200095881A KR20200095881A (ko) 2020-08-11
KR102277657B1 KR102277657B1 (ko) 2021-07-15
KR102277657B9 true KR102277657B9 (ko) 2023-02-23

Family

ID=71842332

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020190013801A KR102277657B1 (ko) 2019-02-01 2019-02-01 뇌 조직 투명화를 이용한 시냅스 기능 장애 평가 방법

Country Status (2)

Country Link
KR (1) KR102277657B1 (ko)
WO (1) WO2020159264A1 (ko)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015062407A (ja) * 2013-08-30 2015-04-09 公益財団法人東京都医学総合研究所 精神・神経疾患モデル動物
ES2973048T3 (es) * 2013-12-27 2024-06-18 Univ Nat Corp Tokyo Medical & Dental Método para el diagnóstico de la enfermedad de Alzheimer y la degeneración lobar frontotemporal, agente de diagnóstico, agente terapéutico y método de cribado ("screening") para dichos agentes
KR20150085578A (ko) 2014-01-16 2015-07-24 서울대학교산학협력단 지방줄기세포 추출물을 포함하는 신경계 질환 치료 또는 예방용 약학 조성물
EP3273218A4 (en) * 2015-03-18 2018-12-26 Riken Method for observing biological material and clearing method
KR101866249B1 (ko) * 2016-11-29 2018-06-12 박순현 생체 조직 투명화용 조성물 및 이를 이용한 생체 조직 투명화 방법
KR101849704B1 (ko) * 2017-08-21 2018-04-18 한국화학연구원 생체 조직의 투명화 전처리 방법 및 이를 포함하는 생체 조직의 투명화 방법

Also Published As

Publication number Publication date
KR102277657B1 (ko) 2021-07-15
KR20200095881A (ko) 2020-08-11
WO2020159264A1 (ko) 2020-08-06

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E701 Decision to grant or registration of patent right
G170 Re-publication after modification of scope of protection [patent]