KR102266299B1 - Ｇｌｐ-1 펩티드의 조성물 및 그것의 제조 - Google Patents

Ｇｌｐ-1 펩티드의 조성물 및 그것의 제조 Download PDF

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Publication number
KR102266299B1
KR102266299B1 KR1020207002513A KR20207002513A KR102266299B1 KR 102266299 B1 KR102266299 B1 KR 102266299B1 KR 1020207002513 A KR1020207002513 A KR 1020207002513A KR 20207002513 A KR20207002513 A KR 20207002513A KR 102266299 B1 KR102266299 B1 KR 102266299B1
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KR
South Korea
Prior art keywords
ethoxy
glp
minutes
amino
peptide
Prior art date
Application number
KR1020207002513A
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English (en)
Korean (ko)
Other versions
KR20200013078A (ko
Inventor
토마스 빈헬름센
헬레 엘리아센
튜 한센
Original Assignee
노보 노르디스크 에이/에스
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 노보 노르디스크 에이/에스 filed Critical 노보 노르디스크 에이/에스
Priority claimed from PCT/EP2013/055362 external-priority patent/WO2013139694A1/en
Publication of KR20200013078A publication Critical patent/KR20200013078A/ko
Application granted granted Critical
Publication of KR102266299B1 publication Critical patent/KR102266299B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
KR1020207002513A 2012-03-22 2013-03-15 Ｇｌｐ-1 펩티드의 조성물 및 그것의 제조 KR102266299B1 (ko)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
EP12160743.6 2012-03-22
EP12160743 2012-03-22
US201361748840P 2013-01-04 2013-01-04
US61/748,840 2013-01-04
EP13153459 2013-01-31
EP13153459.6 2013-01-31
PCT/EP2013/055362 WO2013139694A1 (en) 2012-03-22 2013-03-15 Compositions of glp-1 peptides and preparation thereof
KR1020147028164A KR102072202B1 (ko) 2012-03-22 2013-03-15 Ｇｌｐ-1 펩티드의 조성물 및 그것의 제조

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020147028164A Division KR102072202B1 (ko) 2012-03-22 2013-03-15 Ｇｌｐ-1 펩티드의 조성물 및 그것의 제조

Publications (2)

Publication Number Publication Date
KR20200013078A KR20200013078A (ko) 2020-02-05
KR102266299B1 true KR102266299B1 (ko) 2021-06-18

Family

ID=65910839

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207002513A KR102266299B1 (ko) 2012-03-22 2013-03-15 Ｇｌｐ-1 펩티드의 조성물 및 그것의 제조

Country Status (4)

Country Link
KR (1) KR102266299B1 (pt)
CY (1) CY1120767T1 (pt)
IL (1) IL234228B (pt)
PT (1) PT2827885T (pt)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006097537A2 (en) * 2005-03-18 2006-09-21 Novo Nordisk A/S Acylated glp-1 compounds
US20090124639A1 (en) * 2007-11-06 2009-05-14 Emisphere Technologies Inc. valacyclovir formulations
WO2010020978A1 (en) * 2008-08-18 2010-02-25 Oramed Pharmaceuticals Ltd Methods and compositions for oral administration of proteins
US20100239658A1 (en) * 2006-06-28 2010-09-23 Emisphere Technologies, Inc. Gallium nitrate formulations
WO2011138421A1 (en) * 2010-05-05 2011-11-10 Boehringer Ingelheim International Gmbh Combination therapy
KR102072202B1 (ko) * 2012-03-22 2020-01-31 노보 노르디스크 에이/에스 Ｇｌｐ-1 펩티드의 조성물 및 그것의 제조

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006097537A2 (en) * 2005-03-18 2006-09-21 Novo Nordisk A/S Acylated glp-1 compounds
US20100239658A1 (en) * 2006-06-28 2010-09-23 Emisphere Technologies, Inc. Gallium nitrate formulations
US20090124639A1 (en) * 2007-11-06 2009-05-14 Emisphere Technologies Inc. valacyclovir formulations
WO2010020978A1 (en) * 2008-08-18 2010-02-25 Oramed Pharmaceuticals Ltd Methods and compositions for oral administration of proteins
WO2011138421A1 (en) * 2010-05-05 2011-11-10 Boehringer Ingelheim International Gmbh Combination therapy
KR102072202B1 (ko) * 2012-03-22 2020-01-31 노보 노르디스크 에이/에스 Ｇｌｐ-1 펩티드의 조성물 및 그것의 제조

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Clinical Pharmacology and Therapeutics, 84(4), 2008.10., pp.468-474*

Also Published As

Publication number Publication date
KR20200013078A (ko) 2020-02-05
IL234228B (en) 2019-03-31
PT2827885T (pt) 2018-11-05
CY1120767T1 (el) 2019-12-11

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X701 Decision to grant (after re-examination)