KR102248449B9 - 신규한 클로린 e6-커큐민 유도체, 그 제조 방법 및 그것을 함유하는 암 치료용 약학 조성물 - Google Patents
신규한 클로린 e6-커큐민 유도체, 그 제조 방법 및 그것을 함유하는 암 치료용 약학 조성물Info
- Publication number
- KR102248449B9 KR102248449B9 KR1020170080023A KR20170080023A KR102248449B9 KR 102248449 B9 KR102248449 B9 KR 102248449B9 KR 1020170080023 A KR1020170080023 A KR 1020170080023A KR 20170080023 A KR20170080023 A KR 20170080023A KR 102248449 B9 KR102248449 B9 KR 102248449B9
- Authority
- KR
- South Korea
- Prior art keywords
- cancer
- treatment
- pharmaceutical composition
- composition containing
- same
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
- A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020170080023A KR102248449B1 (ko) | 2017-06-23 | 2017-06-23 | 신규한 클로린 e6-커큐민 유도체, 그 제조 방법 및 그것을 함유하는 암 치료용 약학 조성물 |
PCT/KR2018/007124 WO2018236193A1 (en) | 2017-06-23 | 2018-06-22 | NOVEL CHLORIN E6-CURCUMINE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR THE TREATMENT OF CANCER |
US16/724,703 US20200172549A1 (en) | 2017-06-23 | 2019-12-23 | Novel chlorin e6-curcumin derivatives, preparation method thereof, and pharmaceutical composition containing the same for treatment of cancer |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020170080023A KR102248449B1 (ko) | 2017-06-23 | 2017-06-23 | 신규한 클로린 e6-커큐민 유도체, 그 제조 방법 및 그것을 함유하는 암 치료용 약학 조성물 |
Publications (3)
Publication Number | Publication Date |
---|---|
KR20190000971A KR20190000971A (ko) | 2019-01-04 |
KR102248449B1 KR102248449B1 (ko) | 2021-05-06 |
KR102248449B9 true KR102248449B9 (ko) | 2022-03-15 |
Family
ID=64736035
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020170080023A KR102248449B1 (ko) | 2017-06-23 | 2017-06-23 | 신규한 클로린 e6-커큐민 유도체, 그 제조 방법 및 그것을 함유하는 암 치료용 약학 조성물 |
Country Status (3)
Country | Link |
---|---|
US (1) | US20200172549A1 (ko) |
KR (1) | KR102248449B1 (ko) |
WO (1) | WO2018236193A1 (ko) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101344303B1 (ko) * | 2011-10-07 | 2013-12-24 | 동성제약주식회사 | 표적 치료에 관한 종양에 선택성이 있는 콘쥬게이트 |
CN103224499B (zh) * | 2013-04-07 | 2015-06-03 | 华南理工大学 | 具有光敏活性的脱镁叶绿酸姜黄素酯及其制备方法与应用 |
KR101582306B1 (ko) | 2013-04-22 | 2016-01-05 | 애니젠 주식회사 | 커큐민에 비하여 용해도가 향상된 커큐민―펩타이드 복합체 및 이의 제조방법 |
-
2017
- 2017-06-23 KR KR1020170080023A patent/KR102248449B1/ko active IP Right Grant
-
2018
- 2018-06-22 WO PCT/KR2018/007124 patent/WO2018236193A1/en active Application Filing
-
2019
- 2019-12-23 US US16/724,703 patent/US20200172549A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20200172549A1 (en) | 2020-06-04 |
KR20190000971A (ko) | 2019-01-04 |
KR102248449B1 (ko) | 2021-05-06 |
WO2018236193A1 (en) | 2018-12-27 |
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Legal Events
Date | Code | Title | Description |
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E902 | Notification of reason for refusal | ||
AMND | Amendment | ||
E601 | Decision to refuse application | ||
X091 | Application refused [patent] | ||
AMND | Amendment | ||
X701 | Decision to grant (after re-examination) | ||
GRNT | Written decision to grant | ||
G170 | Re-publication after modification of scope of protection [patent] |