KR102207696B9 - 뇌미세혈관 손상 뇌질환 진단용 바이오 마커 조성물 - Google Patents

뇌미세혈관 손상 뇌질환 진단용 바이오 마커 조성물

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Publication number
KR102207696B9
KR102207696B9 KR20190168269A KR20190168269A KR102207696B9 KR 102207696 B9 KR102207696 B9 KR 102207696B9 KR 20190168269 A KR20190168269 A KR 20190168269A KR 20190168269 A KR20190168269 A KR 20190168269A KR 102207696 B9 KR102207696 B9 KR 102207696B9
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KR
South Korea
Prior art keywords
brain
diagnosis
blood
diseases due
biomarker composition
Prior art date
Application number
KR20190168269A
Other languages
English (en)
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KR20210000250A (ko
KR102207696B1 (ko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020190075235A external-priority patent/KR102100588B1/ko
Application filed filed Critical
Priority to KR1020190168269A priority Critical patent/KR102207696B1/ko
Priority to PCT/KR2020/008165 priority patent/WO2020262937A1/ko
Publication of KR20210000250A publication Critical patent/KR20210000250A/ko
Application granted granted Critical
Publication of KR102207696B9 publication Critical patent/KR102207696B9/ko
Publication of KR102207696B1 publication Critical patent/KR102207696B1/ko

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00Modified animals
    • A01K2207/35Animals modified by environmental factors, e.g. temperature, O2
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/60Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Animal Husbandry (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020190168269A 2019-06-24 2019-12-16 뇌미세혈관 손상 뇌질환 진단용 바이오 마커 조성물 KR102207696B1 (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1020190168269A KR102207696B1 (ko) 2019-06-24 2019-12-16 뇌미세혈관 손상 뇌질환 진단용 바이오 마커 조성물
PCT/KR2020/008165 WO2020262937A1 (ko) 2019-06-24 2020-06-23 뇌미세혈관 손상 뇌질환 진단용 바이오 마커 조성물

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020190075235A KR102100588B1 (ko) 2019-06-24 2019-06-24 뇌미세혈관 손상 뇌질환 진단용 바이오 마커 조성물
KR1020190168269A KR102207696B1 (ko) 2019-06-24 2019-12-16 뇌미세혈관 손상 뇌질환 진단용 바이오 마커 조성물

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020190075235A Division KR102100588B1 (ko) 2019-06-24 2019-06-24 뇌미세혈관 손상 뇌질환 진단용 바이오 마커 조성물

Publications (3)

Publication Number Publication Date
KR20210000250A KR20210000250A (ko) 2021-01-04
KR102207696B9 true KR102207696B9 (ko) 2021-01-26
KR102207696B1 KR102207696B1 (ko) 2021-01-26

Family

ID=74130466

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020190168269A KR102207696B1 (ko) 2019-06-24 2019-12-16 뇌미세혈관 손상 뇌질환 진단용 바이오 마커 조성물

Country Status (1)

Country Link
KR (1) KR102207696B1 (ko)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6472140B1 (en) 1997-09-05 2002-10-29 The General Hospital Corporation α-2- macroglobulin therapies and drug screening methods for Alzheimer's disease.
DE10242016A1 (de) 2002-09-11 2004-03-25 Esplora GmbH c/o TU Darmstadt Institut für Biochemie Verfahren zur Identifizierung BHS-spezifischer Proteine und Fragmente davon
US20060263783A1 (en) 2003-07-03 2006-11-23 Podhajcer Osvaldo L Methods and systems for diagnosis of non-central nervous system (cns) diseases in cns samples
JP4667372B2 (ja) 2004-02-25 2011-04-13 株式会社ペルセウスプロテオミクス 血管障害の程度の判定方法
JP2009020049A (ja) 2007-07-13 2009-01-29 Univ Of Tokyo 脳血管疾患の診断方法
KR102034311B1 (ko) * 2017-09-15 2019-10-18 경북대학교 산학협력단 리포칼린-2를 이용한 혈관성 치매의 진단방법

Also Published As

Publication number Publication date
KR20210000250A (ko) 2021-01-04
KR102207696B1 (ko) 2021-01-26

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