KR102194611B1 - 티로신 수용체 키나아제 btk 억제제로서 치환된 n-(3-(피리미딘-4-일)페닐)아크릴아미드 유사체 - Google Patents

티로신 수용체 키나아제 btk 억제제로서 치환된 n-(3-(피리미딘-4-일)페닐)아크릴아미드 유사체 Download PDF

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KR102194611B1
KR102194611B1 KR1020157011753A KR20157011753A KR102194611B1 KR 102194611 B1 KR102194611 B1 KR 102194611B1 KR 1020157011753 A KR1020157011753 A KR 1020157011753A KR 20157011753 A KR20157011753 A KR 20157011753A KR 102194611 B1 KR102194611 B1 KR 102194611B1
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hydrogen
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polyhaloalkyl
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KR20150067759A (ko
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하리프라사드 반카얄라파티
벤카타스와미 소르나
스티븐 엘. 워너
데이비드 제이 베얼스
수닐 샤르마
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유니버시티 오브 유타 리서치 파운데이션
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KR1020157011753A 2012-10-04 2013-10-04 티로신 수용체 키나아제 btk 억제제로서 치환된 n-(3-(피리미딘-4-일)페닐)아크릴아미드 유사체 Expired - Fee Related KR102194611B1 (ko)

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Application Number Priority Date Filing Date Title
US201261709519P 2012-10-04 2012-10-04
US61/709,519 2012-10-04
PCT/US2013/063549 WO2014055928A2 (en) 2012-10-04 2013-10-04 Substituted n-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase btk inhibitors

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KR20150067759A KR20150067759A (ko) 2015-06-18
KR102194611B1 true KR102194611B1 (ko) 2020-12-23

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US (2) US9828376B2 (enExample)
EP (2) EP2903972B1 (enExample)
JP (1) JP6401169B2 (enExample)
KR (1) KR102194611B1 (enExample)
CN (1) CN104822664B (enExample)
CA (1) CA2887435A1 (enExample)
WO (1) WO2014055928A2 (enExample)

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WO2012135801A1 (en) 2011-04-01 2012-10-04 University Of Utah Research Foundation Substituted n-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase btk inhibitors
WO2014055934A2 (en) 2012-10-04 2014-04-10 University Of Utah Research Foundation Substituted n-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase btk inhibitors
KR102194611B1 (ko) * 2012-10-04 2020-12-23 유니버시티 오브 유타 리서치 파운데이션 티로신 수용체 키나아제 btk 억제제로서 치환된 n-(3-(피리미딘-4-일)페닐)아크릴아미드 유사체
US9512084B2 (en) 2013-11-29 2016-12-06 Novartis Ag Amino pyrimidine derivatives
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CN117281803A (zh) 2018-07-31 2023-12-26 罗索肿瘤学公司 喷雾干燥的分散体和制剂
US12157730B2 (en) 2019-03-19 2024-12-03 Voronoi Inc. Heteroaryl derivative, method for producing same, and pharmaceutical composition comprising same as effective component
MA55380A (fr) 2019-03-19 2022-01-26 B2Sbio Inc Dérivé hétéroaryle, son procédé de production et composition pharmaceutique le comprenant en tant que constituant efficace
JP2022526713A (ja) 2019-03-21 2022-05-26 オンクセオ がんの処置のための、キナーゼ阻害剤と組み合わせたＤｂａｉｔ分子
KR20220098759A (ko) 2019-11-08 2022-07-12 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) 키나제 억제제에 대해 내성을 획득한 암의 치료 방법
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KR102194611B1 (ko) 2012-10-04 2020-12-23 유니버시티 오브 유타 리서치 파운데이션 티로신 수용체 키나아제 btk 억제제로서 치환된 n-(3-(피리미딘-4-일)페닐)아크릴아미드 유사체

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HK1213243A1 (en) 2016-06-30
KR20150067759A (ko) 2015-06-18
EP2903972A2 (en) 2015-08-12
US20180134719A1 (en) 2018-05-17
JP2015532304A (ja) 2015-11-09
US20150252048A1 (en) 2015-09-10
EP2903972A4 (en) 2016-04-06
WO2014055928A3 (en) 2014-06-26
CN104822664A (zh) 2015-08-05
WO2014055928A2 (en) 2014-04-10
US9828376B2 (en) 2017-11-28
EP2903972B1 (en) 2019-12-04
CN104822664B (zh) 2017-01-18
EP3680238A1 (en) 2020-07-15
CA2887435A1 (en) 2014-04-10
JP6401169B2 (ja) 2018-10-03

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