KR102106762B1 - 에를리히아 항체의 검출을 위한 펩티드, 장치, 그리고 방법 - Google Patents

에를리히아 항체의 검출을 위한 펩티드, 장치, 그리고 방법 Download PDF

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KR102106762B1
KR102106762B1 KR1020157010378A KR20157010378A KR102106762B1 KR 102106762 B1 KR102106762 B1 KR 102106762B1 KR 1020157010378 A KR1020157010378 A KR 1020157010378A KR 20157010378 A KR20157010378 A KR 20157010378A KR 102106762 B1 KR102106762 B1 KR 102106762B1
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amino acid
group
acid selected
seq
peptides
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KR20150065744A (ko
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라제시 케이. 메라
케네쓰 피. 아론
데니스 엠. 블레일레
티모씨 피. 포사이스
제레미 디. 워커
크리스티나 알. 쿠에시코
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아박시스, 인크.
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/29—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Richettsiales (O)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/14—Peptides being immobilised on, or in, an inorganic carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/29—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Richettsiales (o)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Cell Biology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020157010378A 2012-10-11 2013-10-11 에를리히아 항체의 검출을 위한 펩티드, 장치, 그리고 방법 Active KR102106762B1 (ko)

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US201261712578P 2012-10-11 2012-10-11
US61/712,578 2012-10-11
PCT/US2013/064536 WO2014059274A1 (en) 2012-10-11 2013-10-11 Peptides, devices, and methods for the detection of ehrlichia antibodies

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KR20150065744A KR20150065744A (ko) 2015-06-15
KR102106762B1 true KR102106762B1 (ko) 2020-05-06

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US (5) US9651546B2 (https=)
EP (1) EP2906950B1 (https=)
JP (1) JP6325553B2 (https=)
KR (1) KR102106762B1 (https=)
CN (1) CN105051541B (https=)
AU (1) AU2013329025B2 (https=)
BR (1) BR112015008036B1 (https=)
CA (1) CA2886989C (https=)
ES (1) ES2668863T3 (https=)
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Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6161291B2 (ja) 2009-11-20 2017-07-12 アバクシス， インコーポレイテッド エールリッヒア抗体の検出のためのペプチド、装置、および方法
PT3489685T (pt) 2011-11-21 2024-01-04 Zoetis Services Llc Amplificação de sinais em imunoensaios de fluxo lateral e relacionados
BR112015008036B1 (pt) * 2012-10-11 2022-09-13 Zoetis Services Llc População de peptídeos isolados, método para detectar em uma amostra um anticorpo, método para diagnosticar erliquiose monocítica e/ou granulocítica, método para detectar a presença de anticorpos e kit
US9194870B2 (en) 2014-01-21 2015-11-24 Abaxis, Inc. Peptides, devices, and methods for the detection of Anaplasma antibodies
US9442112B2 (en) 2014-04-04 2016-09-13 Abaxis, Inc. Compositions and methods for identifying Ehrlichia species
TWI691716B (zh) 2014-08-13 2020-04-21 美商艾巴希斯公司 電漿特異性結合搭配物檢定中之信號放大
EP4465021A3 (en) 2015-08-04 2025-02-26 Zoetis Services LLC Signal amplification in solution-based plasmonic specific-binding partner assays
US20200209226A1 (en) * 2017-01-20 2020-07-02 Shenzhen New Industries Biomedical Engineering Co. Labeled complex, preparation method thereof, kit containing the same, application of kit and detection system comprising kit
WO2018140953A1 (en) 2017-01-30 2018-08-02 Abaxis, Inc. Solution-based plasmon specific-binding partner assays and metallic nanostructures
US12377139B2 (en) * 2017-07-12 2025-08-05 Kansas State University Research Foundation Ehrlichia ruminantium immunogenic compositions and methods of using thereof
EP3775896B1 (en) 2018-04-03 2023-06-07 Sanofi Lateral flow immunoassay strip device
US20240272168A1 (en) * 2023-02-14 2024-08-15 Advanced Biosystems, Inc. Immunostaining using protein conjugates

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000032745A2 (en) 1998-11-30 2000-06-08 Research Development Foundation Homologous 28-kilodalton immunodominant protein genes of ehrlichia canis and uses thereof
US20030103991A1 (en) 1998-09-18 2003-06-05 Yasuko Rikihisa Outer membrane protein of Ehrlichia canis and Ehrlichia chaffeensis
WO2008137881A2 (en) 2007-05-04 2008-11-13 The Ohio State University Research Foundation Ehrlichia ewingii proteins, nucleic acids, and methods of their use
US20110124125A1 (en) * 2009-11-20 2011-05-26 Abaxis, Inc. Peptides, devices, and methods for the detection of ehrlichia antibodies

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4366246A (en) 1977-11-08 1982-12-28 Genentech, Inc. Method for microbial polypeptide expression
US4617262A (en) * 1983-07-22 1986-10-14 Cooperbiomedical, Inc. Assaying for circulating immune complexes with labeled protein A
US6284238B1 (en) 1995-06-06 2001-09-04 Aquila Biopharmaceuticals, Inc. Cell lines infected with granulocytic ehrlichia, vaccines, diagnostics and methods
US6451315B1 (en) 1996-10-01 2002-09-17 Corixa Corporation Compounds and methods for the diagnosis and treatment of B. microti infection
US6653128B2 (en) 1996-10-17 2003-11-25 University Of Florida Nucleic acid vaccines against rickettsial diseases and methods of use
US6593147B1 (en) * 1996-10-17 2003-07-15 University Of Florida Research Foundation, Inc. Nucleic acid vaccines against rickettsial diseases and methods of use
US6231869B1 (en) 1997-03-21 2001-05-15 Corixa Corporation Compounds and methods for the diagnosis and treatment of ehrlichia infection
US6207169B1 (en) 1997-03-21 2001-03-27 Corixa Corporation Compounds and methods for the diagnosis and treatment of Ehrlichia infection
EP2311957A1 (en) 1997-04-25 2011-04-20 Antigenics Inc. Antigens from granulocytic Ehrlichia
DE69841899D1 (de) 1997-09-19 2010-10-28 Ohio State Res Found Proteine der äusseren membran von ehrlichia chaffeensis
EP1100917A1 (en) 1998-07-28 2001-05-23 Aquila Biopharmaceuticals, Inc. Granulocytic ehrlichia genes and uses thereof
US6043085A (en) 1998-08-27 2000-03-28 Research Development Foundation Ehrlichia canis 120-kDa immunodominant antigenic protein and gene
US6544517B1 (en) 1998-09-18 2003-04-08 The Ohio State University Research Foundation Outer membrane protein of Ehrlichia canis and Ehrlichia chaffeensis
US7888491B2 (en) 1998-09-18 2011-02-15 The Ohio State University Research Foundation Outer membrane protein of Ehrlichia canis and Ehrlichia chaffeensis
US6392023B1 (en) 1999-03-03 2002-05-21 Research Development Foundation Homologous 28-kilodalton immunodominant protein genes of Ehrlicha canis and uses thereof
BR0012556A (pt) 1999-07-21 2002-07-02 Cornell Res Foundation Inc Genes e vacinas de ehrlichia canis
US6355777B1 (en) 2000-04-28 2002-03-12 Research Development Foundation P43 antigen for the immunodiagnosis of canine ehrlichiosis and uses thereof
US7087372B2 (en) 2001-01-18 2006-08-08 Idexx Laboratories, Inc. Compositions and methods for detection of Ehrlichia canis and Ehrlichia chaffeensis antibodies
US7183060B2 (en) 2005-02-22 2007-02-27 Idexx Laboratories, Inc. Peptides for detection of antibody to Ehrlichia ewingii
US20030194756A1 (en) 2002-04-12 2003-10-16 O'connor Thomas Patrick Peptides for detection of antibody to Ehrlichia equi
US7407770B2 (en) 2001-01-18 2008-08-05 Idexx Corporation Compositions and methods for detection of Ehrlichia canis and Ehrlichia chaffeensis antibodies
PT1384075E (pt) 2001-03-28 2010-03-23 Heska Corp Métodos de detecção de doença renal inicial em animais
US20030129161A1 (en) 2001-09-17 2003-07-10 Hsien-Jue Chu Interleukin-12 as a veterinary vaccine adjuvant
BRPI0315980B1 (pt) 2002-11-04 2016-03-29 Res Dev Foundation dna codificando o antígeno p156 de ehrlichia chaffeensis, vetor, célula hospedeira, vacina compreendendo o mesmo, processos para determinar se um cão está infectado com ehrlichia chaffeensis e kits para a realização dos referidos processos
WO2004084841A2 (en) 2003-03-27 2004-10-07 Heska Corporation Novel anti-feline albumin antibodies and methods of detecting early renal disease
US7304139B2 (en) 2003-10-28 2007-12-04 University Of Florida Research Foundation, Inc. Polynucleotides and polypeptides of Anaplasma phagocytophilum and methods of using the same
US20050202046A1 (en) 2004-03-11 2005-09-15 Wyeth Canine vaccine for protection against ehrlichiosis
US20060046310A1 (en) 2004-08-25 2006-03-02 Zong-Li Xia Amplification method for solid phase immunoassays
WO2006107924A2 (en) 2005-04-04 2006-10-12 Idexx Laboratories, Inc. Ehrlichia canis diva (differentiate infected from vaccinated animals)
US7842474B2 (en) 2005-04-04 2010-11-30 Idexx Laboratories, Inc. Ehrlichia canis DIVA (differentiate infected from vaccinated animals)
US8591906B2 (en) 2005-06-16 2013-11-26 Research Development Foundation Immunoreactive protein orthologs of Ehrlichia canis and E. chaffeensis
US20090176208A1 (en) 2006-01-04 2009-07-09 Simon Brodie Methods for detecting, identifying and reporting the presence of animal pathological agents
US7776618B2 (en) 2007-03-01 2010-08-17 Church & Dwight Co., Inc. Diagnostic detection device
US7507789B2 (en) 2007-04-09 2009-03-24 Idexx Laboratories, Inc. Detection of Anaplasma platys
EP2203469A4 (en) 2007-09-21 2011-08-24 Idexx Lab Inc METHOD AND COMPOSITIONS FOR IDENTIFYING EHRLICHIA CHAFFEENSIS (P120)
CA2700476C (en) 2007-09-21 2017-11-28 Idexx Laboratories, Inc. Methods and compositions for detection of ehrlichia chaffeensis variable-length pcr target
KR101621038B1 (ko) 2007-10-31 2016-05-16 아이덱스 래보러토리즈, 인코포레이티드 에를리히아 카니스 ｄｉｖａ（감염된 동물을 백신접종된 동물과 구별）
BR112015008036B1 (pt) 2012-10-11 2022-09-13 Zoetis Services Llc População de peptídeos isolados, método para detectar em uma amostra um anticorpo, método para diagnosticar erliquiose monocítica e/ou granulocítica, método para detectar a presença de anticorpos e kit
CN103060468B (zh) 2013-01-30 2014-02-12 扬州大学 一种埃里希氏菌的荧光定量pcr检测和分型的引物、探针及试剂盒
US9442112B2 (en) 2014-04-04 2016-09-13 Abaxis, Inc. Compositions and methods for identifying Ehrlichia species

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030103991A1 (en) 1998-09-18 2003-06-05 Yasuko Rikihisa Outer membrane protein of Ehrlichia canis and Ehrlichia chaffeensis
WO2000032745A2 (en) 1998-11-30 2000-06-08 Research Development Foundation Homologous 28-kilodalton immunodominant protein genes of ehrlichia canis and uses thereof
WO2008137881A2 (en) 2007-05-04 2008-11-13 The Ohio State University Research Foundation Ehrlichia ewingii proteins, nucleic acids, and methods of their use
US20110124125A1 (en) * 2009-11-20 2011-05-26 Abaxis, Inc. Peptides, devices, and methods for the detection of ehrlichia antibodies

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Asiyaa Gusa et al, Journal of Clinical Microbiology (2011), vol 39, no 11, pp 3871-3876.
Zhang Chunbin et al, Clinical and Vaccine Immunology (2008), vol 15, no 3, pp 402-411.

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EP2906950A1 (en) 2015-08-19
BR112015008036B1 (pt) 2022-09-13
ES2668863T3 (es) 2018-05-22
AU2013329025B2 (en) 2019-07-04
JP6325553B2 (ja) 2018-05-16
EP2906950B1 (en) 2018-03-21
US9651546B2 (en) 2017-05-16
US20160054313A1 (en) 2016-02-25
EP2906950A4 (en) 2016-05-25
CN105051541A (zh) 2015-11-11
US20180106792A1 (en) 2018-04-19
US20140121125A1 (en) 2014-05-01
AU2013329025A1 (en) 2015-04-23
CA2886989C (en) 2022-05-17
US9696300B2 (en) 2017-07-04
KR20150065744A (ko) 2015-06-15
CN105051541B (zh) 2017-07-04
WO2014059274A1 (en) 2014-04-17
JP2016500815A (ja) 2016-01-14
US20190391139A1 (en) 2019-12-26
CA2886989A1 (en) 2014-04-17
US20140212898A1 (en) 2014-07-31
US10444231B2 (en) 2019-10-15
US10948487B2 (en) 2021-03-16
BR112015008036A2 (pt) 2017-11-28
US9157913B2 (en) 2015-10-13

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