KR102032251B1 - Image sensor module, small size digital microscope and small size digital microscope array system - Google Patents

Abstract

Provided are an image sensor module, a microscope, and a microscope array system which can simplify an optical system to realize miniaturization and to reduce a blur occurring in a peripheral part of a photographed image. The image sensor module comprises a mount to which an objective lens module for determining magnification of the photographed image is coupled, and a lens-free image sensor on which light transmitted through the objective lens module is incident. A micro lens shift value of each pixel of the lens-free image sensor is designed to correspond to a chief ray angle (CRA) value of the objective lens module.

Description

Image sensor modules, small digital microscopes and small digital microscope array systems {IMAGE SENSOR MODULE, SMALL SIZE DIGITAL MICROSCOPE AND SMALL SIZE DIGITAL MICROSCOPE ARRAY SYSTEM}

The present invention relates to an image sensor module, a small digital microscope and a small digital microscope array system.

As shown in FIG. 1, a conventional digital microscope may include an objective lens, a camera module, a tube lens and an extension tube for optically connecting the objective lens and the camera module.

However, the conventional digital microscope has a problem that the manufacturing process is complicated and the defect rate increases because the optical axis of the various optical systems must be aligned, there is a problem that the length of the overall length is lengthened by various optical systems, there is a limit to the miniaturization of the product, the manufacturing cost There is a growing problem.

Furthermore, in the conventional optical digital microscope, aberration is greatly generated by various optical systems, and a blur phenomenon occurs in a peripheral portion of the captured image (the portion picked up at the edge region of the image sensor).

Meanwhile, as shown in FIG. 2, the image sensor includes a plurality of pixels, and each of the plurality of pixels includes a micro lens array (MLA) and an RGB filter (a filter for selectively transmitting at least one of the RGB wavelength bands). And an imaging element (IMAGING ELEMENT). In this case, in the conventional digital microscope, the incident angles (CRA) of the chief rays of light incident on the plurality of pixels in the central region (b) and the edge regions (a, c) of the image sensor are caused by the light refraction effect of the tube lens and the expansion tube. Chief Ray Angle) difference is about 25 degrees.

To solve this problem, the microlens shift value of each pixel is calculated (the spacing of pixels is uniform as the center goes to the edge, but the microlens shift value becomes smaller, that is, the spacing between the microlenses becomes narrower from the center to the edge). In this case, the microlenses are intentionally moved to deviate from the axis of the imaging element. In the conventional digital microscope, an optical system such as a tube lens and an expansion tube is essentially required to consider the design of the micro lens shift.

Korean Laid-Open Patent Publication No. 1999-0045860, 1999.06.25. open

SUMMARY OF THE INVENTION An object of the present invention is to provide an image sensor module, a microscope, and a microscope array system capable of realizing miniaturization by simplifying an optical system and reducing blur in a peripheral portion of a captured image.

Problems to be solved by the present invention are not limited to the above-mentioned problems, and other problems not mentioned will be clearly understood by those skilled in the art from the following description.

An image sensor module according to an aspect of the present invention for solving the above problems is a mount coupled to the objective lens module for determining the magnification of the captured image; And a lens free image sensor to which light transmitted through the objective lens module is incident, wherein a microlens shift value of each pixel of the lens free image sensor is designed to correspond to a chief ray angle (CRA) value of the objective lens module. Can be.

An image sensor module according to an aspect of the present invention for solving the above problems is a mount coupled to the objective lens module for determining the magnification of the captured image; And a lens free image sensor through which light transmitted through the objective lens module is incident, and a chief ray angle (CRA) value of each pixel of the lens free image sensor may be 0 degrees.

An image sensor module according to an aspect of the present invention for solving the above problems is a mount coupled to the objective lens module for determining the magnification of the captured image; A lens free image sensor may include a lens free image sensor through which light transmitted through the objective lens module is incident, and a chief ray angle (CRA) value of a pixel located at the outermost side of each pixel of the lens free image sensor may be 5 degrees or less.

A microscope according to an aspect of the present invention for solving the above problems is an objective lens module for determining the magnification of the captured image; And an image sensor module including a lens free image sensor to which light transmitted through the objective lens module is incident, wherein a microlens shift value of each pixel of the lens free image sensor is a chief ray angle of the objective lens module. Value).

A microscope according to an aspect of the present invention for solving the above problems is an objective lens module for determining the magnification of the captured image; The image sensor module may include a lens free image sensor through which light transmitted through the objective lens module is incident, and a chief ray angle (CRA) value of each pixel of the lens free image sensor may be 0 degrees.

A microscope according to an aspect of the present invention for solving the above problems is an objective lens module for determining the magnification of the captured image; And an image sensor module including a lens free image sensor through which light transmitted through the objective lens module is incident, wherein a chief ray angle (CRA) value of a pixel located at the outermost side of each pixel of the lens free image sensor is 5; It may be below.

The objective lens module and the image sensor module may be integrally packaged.

The microscope may further include a dichroic filter disposed between the objective lens module and the image sensor module.

The objective lens module, the image sensor module, and the dichroic filter may be integrally packaged.

The microscope may further include a half mirror disposed between the objective lens module and the image sensor module.

The objective lens module, the image sensor module, and the half mirror may be integrally packaged.

The microscope further includes an auto focusing lens module disposed between the objective lens module and the image sensor module, and light passing through the objective lens module and the auto focusing lens module is incident to the imaging unit. The auto focusing lens module may include one or more optical lenses aligned with respect to the optical axis and a driving unit for driving the one or more optical lenses with respect to the optical axis.

The objective lens module, the auto focusing lens module, and the image sensor module may be integrally packaged.

The microscope may further include a dichroic filter disposed between the objective lens module and the auto focusing lens module.

The objective lens module, the auto focusing lens module, the image sensor, and the dichroic filter may be integrally packaged.

The microscope may further include a half mirror disposed between the objective lens module and the auto focusing lens module.

The objective lens module, the auto focusing lens module, the image sensor, and the half mirror may be integrally packaged.

The microscope array system according to an aspect of the present invention for solving the above problems includes a plurality of microscopes, each of the plurality of microscopes, the objective lens module for determining the magnification of the captured image; And an image sensor module including a lens free image sensor to which light transmitted through the objective lens module is incident, wherein a microlens shift value of each pixel of the lens free image sensor is a chief ray angle of the objective lens module. Value).

The microscope array according to an aspect of the present invention for solving the above problems includes a plurality of microscopes, each of the plurality of microscopes, the objective lens module for determining the magnification of the captured image; The image sensor module may include a lens free image sensor through which light transmitted through the objective lens module is incident, and a chief ray angle (CRA) value of each pixel of the lens free image sensor may be 0 degrees.

The microscope array system according to an aspect of the present invention for solving the above problems includes a plurality of microscopes, each of the plurality of microscopes, the objective lens module for determining the magnification of the captured image; And an image sensor module including a lens free image sensor through which light transmitted through the objective lens module is incident, wherein a chief ray angle (CRA) value of a pixel located at the outermost side of each pixel of the lens free image sensor is 5; It may be below.

In the present invention, the remaining optical lens module (for example, extension tube, tube lens, etc.) except for the objective lens module is omitted (LENS-FREE), so that the magnification of the captured image of the specimen can be enlarged and the optical system can be simplified and miniaturized. An image sensor module, a microscope and a microscope array system are provided.

Therefore, in the present invention, the cost can be reduced, the optical axis can be easily aligned, and the miniaturized feature facilitates simultaneous measurement of large-area specimens (microscopic array formation). Furthermore, in the present invention, blur caused by aberrations of various optical systems can be reduced.

Effects of the present invention are not limited to the effects mentioned above, and other effects not mentioned will be clearly understood by those skilled in the art from the following description.

1 is a conceptual diagram showing a conventional microscope.
FIG. 2 is a conceptual diagram illustrating that chief rays of light are incident on a center region and a peripheral region of a camera image sensor in a conventional microscope.
3 is a conceptual diagram showing a microscope of the present invention.
4 and 5 are conceptual views illustrating that chief rays of light are incident on the central region and the peripheral region of the lens-free image sensor in the microscope of the present invention.
6 is a conceptual diagram illustrating a first modification and a second modification of the microscope of the present invention.
7 is a conceptual diagram illustrating observing and imaging a large-area specimen with a conventional microscope and observing and imaging a large-area specimen with the microscope array system of the present invention.

Advantages and features of the present invention and methods for achieving them will be apparent with reference to the embodiments described below in detail with the accompanying drawings. However, the present invention is not limited to the embodiments disclosed below, but can be embodied in various different forms, and the present embodiments only make the disclosure of the present invention complete, and those of ordinary skill in the art to which the present invention belongs. It is provided to fully inform the skilled worker of the scope of the invention, which is defined only by the scope of the claims.

The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. In this specification, the singular also includes the plural unless specifically stated otherwise in the phrase. As used herein, "comprises" and / or "comprising" does not exclude the presence or addition of one or more other components in addition to the mentioned components. Like reference numerals refer to like elements throughout, and "and / or" includes each and all combinations of one or more of the mentioned components. Although "first", "second", etc. are used to describe various components, these components are of course not limited by these terms. These terms are only used to distinguish one component from another. Therefore, of course, the first component mentioned below may be a second component within the technical spirit of the present invention.

Unless otherwise defined, all terms used in the present specification (including technical and scientific terms) may be used in a sense that can be commonly understood by those skilled in the art. In addition, terms that are defined in a commonly used dictionary are not ideally or excessively interpreted unless they are specifically defined clearly.

The spatially relative terms "below", "beneath", "lower", "above", "upper", and the like, as shown in the figure, It can be used to easily describe a component's correlation with other components. Spatially relative terms are to be understood as including terms in different directions of components in use or operation in addition to the directions shown in the figures. For example, when flipping a component shown in the drawing, a component described as "below" or "beneath" of another component may be placed "above" the other component. Can be. Thus, the exemplary term "below" can encompass both an orientation of above and below. Components may be oriented in other directions as well, so spatially relative terms may be interpreted according to orientation.

Hereinafter, the microscope 100 of the present invention will be described with reference to the drawings. 3 is a conceptual diagram showing a microscope of the present invention, Figures 4 and 5 is a conceptual diagram showing the chief ray incident on the central region and the peripheral region of the lens-free image sensor in the microscope of the present invention, Figure 6 is a microscope of the present invention A conceptual diagram showing a first modification and a second modification of.

The microscope 100 of the present invention can be manufactured in a compact by simplifying the optical system. To this end, the microscope 100 of the present invention may include a light source 1, an objective lens module 10, and an image sensor module 20.

The objective lens module 10 and the image sensor module 20 may be separately manufactured (manufactured separately) and combined (see (1) of FIG. 3), and the objective lens module 10 and the image sensor module 20 may be integrally formed. It may also be packaged as (see FIG. 3 (2)). Meanwhile, the light source 1 may also be integrally packaged together with the objective lens module 10 and the image sensor module 20.

Furthermore, the microscope 100 of the present invention may further include a dichroic filter 40 (can be replaced by a half mirror) in addition to the "light source 1, the objective lens module 10 and the image sensor module 20". (See (3) in FIG. 3). Description of the dichroic filter 40 will be described in detail in the second modification of the microscope of the present invention to be described later.

In the microscope 100 of the present invention, unlike the second modification, the auto focusing lens module 30 is omitted, the light source 1, the objective lens module 10, the image sensor module 20, and the dichroic filter. (40, can be replaced by a half mirror).

In this case, the objective lens module 10, the image sensor module 20, and the dichroic filter 40 may be integrally packaged. Meanwhile, the light source 1 may also be integrally packaged together with the objective lens module 1, the image sensor module 20, and the dichroic filter 40.

In the microscope 100 of the present invention, since the tube lens, the expansion lens, and the like are omitted (LENS-FREE), unlike the conventional microscope, the objective lens module 10 and the image sensor module 20 can be integrally packaged. .

The objective lens module 10 may be a module that determines the magnification of the captured image. Therefore, the observer can magnify and accurately observe the captured image of the sample. The outgoing light of the light source 1 may be irradiated with a specimen, the imaging light of the specimen may be irradiated with the objective lens module 10, and the light transmitted through the objective lens module 10 may be directed to the image sensor module 20. Can be investigated. The imaging light of the specimen is converted according to the magnification of the objective lens module 10, and thus, the image sensor module 20 may generate a captured image enlarged than the actual specimen.

The image sensor module 20 may be a module for converting the imaging light of the specimen transmitted through the objective lens module 10 into a captured image. The image sensor module 20 may include a substrate 21 and a lens free image sensor 22.

The lens free image sensor 22 may be a portion to which the imaging light of the sample transmitted through the objective lens module 10 is irradiated. Therefore, the lens free image sensor 22 may also be referred to as a "image effective area".

In the lens free image sensor 22, a plurality of pixels forming units of a frame of the captured image may be formed. In addition, an area of the lens free image sensor 22 may be divided into a center area b 'and an edge area a' and c 'based on an optical axis. That is, the center area b 'of the lens free image sensor 22 may be located at the center of the optical axis than the edge areas a' and c 'of the lens free image sensor 22.

On the other hand, each of the plurality of pixels (the plurality of pixels of the center region and the edge region) of the lens-free image sensor 22 is sequentially arranged along the incident light path, a micro lens, a filter, and an imaging device. (Imaging element) may be included. In this case, the micro lenses of each of the plurality of pixels of the lens free image sensor 22 may form a micro lens array (MLA). The microlenses of each of the plurality of pixels of the lens-free image sensor 22 may perform a function of guiding the light so that the light is irradiated to the corresponding imaging device. The filter may transmit light in a specific wavelength band. For example, the filter may selectively transmit light of a red wavelength band, selectively transmit light of a green wavelength band, or selectively transmit light of a blue wavelength band (RGB Filter). The imaging device of each of the plurality of pixels may convert the imaging light of the specimen into an optical signal.

Meanwhile, as described above, when the image sensor module 20 is manufactured separately and coupled to various types of objective lens modules 10, the image sensor module 20 may further include a mount 23 for coupling with the objective lens module 10. Can be. In this case, the image sensor module 20 may be detachably coupled with the objective lens module 10, and the objective lens module 10 may be combined with or mounted with the mount 23 of the image sensor module 20. A coupling portion may be provided (see (1) of FIG. 3).

In the microscope 100 of the present invention, the tube lens and the expansion tube are omitted. As a result, the lens free image sensor 22 of the microscope 100 of the present invention should be designed differently from the image sensor of the conventional microscope.

For example, the micro lens shift value of each pixel of the lens free image sensor 22 may be designed to correspond to the chief ray angle (CRA) value of the objective lens module 10. In this case, the microlens shift value may be a size shifted from the center position of the center aligned with the image pickup device, and the CRA value of the objective lens module 10 may be an emission angle of the chief ray transmitted through the objective lens module 10. Can be. Since the transmitted light (output light) of the objective lens module 10 is nearly parallel light, the micro lens shift values may all be the same.

In addition, in the lens free image sensor 22 of the microscope 100 of the present invention, the chief ray angle (CRA) values of each pixel may be the same. Furthermore, the CRA values of each of the fill cells of the lens free image sensor 22 may be equal to 0 degrees (see FIG. 4). That is, the micro lens of each pixel of the lens free image sensor 22 may be designed to be aligned and aligned on the same axis as the image pickup element of each pixel of the lens free image sensor 22. In this case, the CRA value of each pixel of the lens free image sensor 22 may be an incident angle of chief rays of light incident on each pixel of the lens free image sensor 22.

As described above, according to the microscope 100 of the present invention, the chief ray incident angle value is changed by an additional optical system such as a tube lens and an expansion tube in a conventional microscope, so that the microlens shift value becomes smaller from the center region to the edge region. Alternatively, the additional optical system may be omitted (LENS-FREE), so that the chief ray incident angle may be all designed identically, and thus the microlens shift values may be all designed identically.

On the other hand, according to various optical design requests (for example, when the transmitted light of the objective lens module is not close to parallel light), the CRA value of the outermost pixel of each pixel of the lens-free image sensor 22 is 5 degrees. Or below (Degree) (see FIG. 5). Accordingly, the micro lens shift value may also vary.

In this case, the outermost pixel may be a pixel located at edge regions a 'and c' of the lens-free image sensor 22. In addition, the outermost pixel may mean a pixel located at the edge of the edge areas a 'and c' of the lens-free image sensor 22.

According to the above, in the microscope 100 of the present invention, the CRA value of the lens free image sensor 22 is designed to be the same as the CRA value of the objective lens module 10, that is, each of the lens free image sensors 22. By designing the microlens shift value of the pixel of to correspond to the CRA value of the objective lens module 10, no additional optics need to be interposed between the objective lens module 10 and the image sensor module 20, resulting in image performance and It can be optimized for optical properties.

EMBODIMENT OF THE INVENTION Hereinafter, the modification of the microscope 100 of this invention is demonstrated with reference to drawings. FIG. 6 is a conceptual diagram showing a first modification example (see FIG. 6 (1)) and a second modification example (see FIG. 6 (2)) of the microscope of the present invention.

In a first modification of the microscope 100 of the present invention, an auto focusing lens module 30 may be added. The auto focusing lens module 30 may be a lens module for varying the focus of the entire lens optical system and focusing the imaging light transmitted through the objective lens 10 on the lens free image sensor 22.

The auto focusing lens module 30 may include a driving unit 32 driving the at least one optical lens 31 and the at least one optical lens 31 in one direction or in both directions with respect to the optical axis direction. In this case, the driving unit 32 may be a stepping motor or a voice coil motor (VCM). When the voice coil motor is used as the driving unit 32, the driving unit 32 may be formed of a coil and a magnet, and by applying an electric current to the coil, by electromagnetic interaction between the coil and the magnet, the optical axis I can drive it.

On the other hand, when the auto focusing lens module 30 is added, the light passing through the objective lens module 10 and the auto focusing lens module 30 in sequence may be incident on the imaging unit 21, and the objective lens module 10 may be incident. ), The image sensor module 20 and the auto focusing lens module 30 may be integrally packaged.

In the second modification of the microscope 100 of the present invention, the dichroic filter 40 may be further added in the first modification. The dichroic filter 40 may be an optical module for acquiring a "fluorescence captured image".

To this end, the dichroic filter 40 may reflect or transmit light of a specific wavelength band. Meanwhile, the dichroic filter 40 may be replaced with a half mirror or an optical film that reflects or transmits light of a specific wavelength band. In this case, the light source 1 may be a light emitting diode (LED) that emits light of a specific wavelength band. For example, the light source 1 may emit laser light having a blue wavelength band.

The dichroic filter 40 may be disposed between the objective lens module 10 and the auto focusing lens module 30. The dichroic filter 40 may reflect light in the first wavelength band and transmit light in the second wavelength band. The light source 1 may emit light of a first wavelength band. The light of the first wavelength band emitted from the light source 1 is reflected by the dichroic filter 40, passes through the objective lens module 10, is converted from the sample into the imaging light of the second wavelength band, and again the object. The lens module 10 may be transmitted to the lens free image sensor 22 through the lens module 10, through the dichroic filter 40, and through the auto focusing lens module 30.

In this case, a fluorescent substance such as a contrast agent may be injected into the sample, and the light excited by the light source 1 passes through the dichroic filter 40, and is then converted into the emission light by the contrast agent of the sample to be dichroic filter. Can be reflected at 40. Meanwhile, according to the optical design change, the excitation light may be reflected by the dichroic filter 40 and the emitted light may pass through the dichroic filter 40.

Hereinafter, the microscope array system 1000 of the present invention will be described with reference to the drawings. Fig. 7 shows observation and imaging of a large area specimen with a conventional microscope (Fig. 7 (1)), and observation and imaging of a large area specimen with a microscope array system of the present invention (Fig. 7 (2)). The conceptual diagram shown.

The microscope array system 1000 of the present invention may include a plurality of microscopes 100 arranged in a predetermined pattern (rule) to form an array. In this case, the plurality of microscopes 100 may be integrally packaged and manufactured, or may be arranged separately to form an array system.

As shown in FIG. 7 (1), the conventional microscope has a problem in that miniaturization is difficult because various optical systems such as an extension tube and an eyepiece module exist in addition to the objective lens module. As a result, there was an inconvenience of moving a sample to observe and pick up a large area of the sample, and observing and picking up a portion of the sample at a time.

However, as shown in Fig. 7 (2), the microscope 100 of the present invention can be miniaturized by omitting the optical system and has a structure suitable for forming an array. Therefore, in the present invention, the microscope array system 1000 has an advantage of observing and capturing all parts of a large-area sample at the same time.

In the above, embodiments of the present invention have been described with reference to the accompanying drawings, but those skilled in the art to which the present invention pertains may implement the present invention in other specific forms without changing the technical spirit or essential features. I can understand that. Therefore, it should be understood that the embodiments described above are exemplary in all respects and not restrictive.

Claims (20)

A mount to which the objective lens module for determining the magnification of the captured image is coupled;
An image sensor module including a lens free image sensor to which light transmitted through the objective lens module is incident; And
An auto focusing lens module disposed between the objective lens module and the image sensor module,
The micro lens shift value of each pixel of the lens free image sensor is designed to correspond to the chief ray angle (CRA) value of the objective lens module.
Light passing through the objective lens module and the auto focusing lens module is sequentially incident on the lens free image sensor.
The auto focusing lens module includes one or more optical lenses aligned with respect to an optical axis, and a driving unit for driving the one or more optical lenses with reference to an optical axis.
A mount to which the objective lens module for determining the magnification of the captured image is coupled;
An image sensor module including a lens free image sensor to which light transmitted through the objective lens module is incident; And
An auto focusing lens module disposed between the objective lens module and the image sensor module,
The chief ray angle (CRA) value of each pixel of the lens free image sensor is 0 degrees,
Light passing through the objective lens module and the auto focusing lens module is sequentially incident on the lens free image sensor.
The auto focusing lens module includes one or more optical lenses aligned with respect to an optical axis, and a driving unit for driving the one or more optical lenses with reference to an optical axis.
A mount to which the objective lens module for determining the magnification of the captured image is coupled;
An image sensor module including a lens free image sensor to which light transmitted through the objective lens module is incident; And
An auto focusing lens module disposed between the objective lens module and the image sensor module,
The chief ray angle (CRA) value of the outermost pixel of each pixel of the lens-free image sensor is 5 degrees or less,
Light passing through the objective lens module and the auto focusing lens module is sequentially incident on the lens free image sensor.
The auto focusing lens module includes one or more optical lenses aligned with respect to an optical axis and a driving unit for driving the one or more optical lenses with reference to an optical axis.
An objective lens module for determining the magnification of the captured image;
An image sensor module including a lens free image sensor to which light transmitted through the objective lens module is incident; And
An auto focusing lens module disposed between the objective lens module and the image sensor module,
The micro lens shift value of each pixel of the lens free image sensor is designed to correspond to the chief ray angle (CRA) value of the objective lens module.
Light passing through the objective lens module and the auto focusing lens module is sequentially incident on the lens free image sensor.
The auto focusing lens module includes one or more optical lenses aligned with respect to an optical axis and a driving unit for driving the one or more optical lenses with reference to an optical axis.
An objective lens module for determining the magnification of the captured image;
An image sensor module including a lens free image sensor to which light transmitted through the objective lens module is incident; And
An auto focusing lens module disposed between the objective lens module and the image sensor module,
The chief ray angle (CRA) value of each pixel of the lens free image sensor is 0 degrees,
Light passing through the objective lens module and the auto focusing lens module is sequentially incident on the lens free image sensor.
The auto focusing lens module includes one or more optical lenses aligned with respect to an optical axis and a driving unit for driving the one or more optical lenses with reference to an optical axis.
An objective lens module for determining the magnification of the captured image;
An image sensor module including a lens free image sensor to which light transmitted through the objective lens module is incident; And
An auto focusing lens module disposed between the objective lens module and the image sensor module,
The chief ray angle (CRA) value of the outermost pixel of each pixel of the lens-free image sensor is 5 degrees or less,
Light passing through the objective lens module and the auto focusing lens module is sequentially incident on the lens free image sensor.
The auto focusing lens module includes one or more optical lenses aligned with respect to an optical axis and a driving unit for driving the one or more optical lenses with reference to an optical axis.
The method according to any one of claims 4 to 6,
And the objective lens module and the image sensor module are integrally packaged.
The method according to any one of claims 4 to 6,
The microscope further comprises a dichroic filter disposed between the objective lens module and the image sensor module.
The method of claim 8,
And the objective lens module, the image sensor module, and the dichroic filter are integrally packaged.
The method according to any one of claims 4 to 6,
The microscope further comprises a half mirror disposed between the objective lens module and the image sensor module.
The method of claim 10,
And the objective lens module, the image sensor module, and the half mirror are integrally packaged.
delete The method according to any one of claims 4 to 6,
And the objective lens module, the auto focusing lens module, and the image sensor module are integrally packaged.
The method according to any one of claims 4 to 6,
And a dichroic filter disposed between the objective lens module and the auto focusing lens module.
The method of claim 14,
And the objective lens module, the auto focusing lens module, the image sensor, and the dichroic filter are integrally packaged.
The method according to any one of claims 4 to 6,
And a half mirror disposed between the objective lens module and the auto focusing lens module.
The method of claim 16,
And the objective lens module, the auto focusing lens module, the image sensor, and the half mirror are integrally packaged.
Including a plurality of microscopes,
Each of the plurality of microscopes,
An objective lens module for determining the magnification of the captured image;
An image sensor module including a lens free image sensor to which light transmitted through the objective lens module is incident; And
An auto focusing lens module disposed between the objective lens module and the image sensor module,
The micro lens shift value of each pixel of the lens free image sensor is designed to correspond to the chief ray angle (CRA) value of the objective lens module.
Light passing through the objective lens module and the auto focusing lens module is sequentially incident on the lens free image sensor.
The auto focusing lens module includes one or more optical lenses aligned with respect to the optical axis and a drive unit for driving the one or more optical lenses with reference to the optical axis.
Including a plurality of microscopes,
Each of the plurality of microscopes,
An objective lens module for determining the magnification of the captured image;
An image sensor module including a lens free image sensor to which light transmitted through the objective lens module is incident; And
An auto focusing lens module disposed between the objective lens module and the image sensor module,
The chief ray angle (CRA) value of each pixel of the lens free image sensor is 0 degrees,
Light passing through the objective lens module and the auto focusing lens module is sequentially incident on the lens free image sensor.
The auto focusing lens module includes one or more optical lenses aligned with respect to the optical axis and a drive unit for driving the one or more optical lenses with reference to the optical axis.
Including a plurality of microscopes,
Each of the plurality of microscopes,
An objective lens module for determining the magnification of the captured image;
An image sensor module including a lens free image sensor to which light transmitted through the objective lens module is incident; And
An auto focusing lens module disposed between the objective lens module and the image sensor module,
The chief ray angle (CRA) value of the outermost pixel of each pixel of the lens-free image sensor is 5 degrees or less,
Light passing through the objective lens module and the auto focusing lens module is sequentially incident on the lens free image sensor.
The auto focusing lens module includes one or more optical lenses aligned with respect to the optical axis and a drive unit for driving the one or more optical lenses with reference to the optical axis.

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