KR101975059B1 - Apparatus for exchanging reagent using removable low temperature storage jacket - Google Patents

Abstract

The present invention relates to a reagent replacement apparatus.
The reagent replacement apparatus using the detachable low temperature reagent storage jacket according to the present invention may include a loading slot in which the quantity of the reagent is adjusted according to the quantity of the reagent, a rotating plate coupled to the loading slot for rotating the reagent, A cooling jacket for keeping the temperature within a range of temperatures, and a syringe pump disposed in the service section.

Description

BACKGROUND OF THE INVENTION 1. Field of the Invention [0001] The present invention relates to a reagent replacement apparatus using a detachable low temperature reagent storage jacket,

The present invention relates to a reagent replacement apparatus.

The reagent is used in various fields such as cell culture, and according to the prior art, the reagent is supplied to the use part through a gear pump or the like.

There is a problem in that the sample exchanging apparatus according to the prior art is not able to load a large amount, it is difficult to control the quantity of the reagent, and there is a limit to load a sample having a limit in temperature and storage period.

In addition, the use time of the reagent at low temperature is limited, and there is a problem that the reagent is very sensitive to continuous use.

The present invention has been proposed in order to solve the above-mentioned problems, and it is an object of the present invention to provide an apparatus capable of providing a reagent replacement type pump structure at low cost and easily storing and replacing reagents using a storage jacket for reagents The purpose is to do.

The reagent replacement apparatus using the detachable low temperature reagent storage jacket according to the present invention may include a loading slot in which the quantity of the reagent is adjusted according to the quantity of the reagent, a rotating plate coupled to the loading slot for rotating the reagent, A cooling jacket for keeping the temperature within a range of temperatures, and a syringe pump disposed in the service section.

According to the configuration of the present invention, it is possible to constitute a reagent replacement type pump at a low cost, reduce personnel and time loss in terms of reagent exchange and management, and improve the convenience of experiment and research.

In addition, it is easy to move and mount in a small volume, and it is possible to minimize the movement of the researcher in research using a sample for freezing or refrigeration.

In addition, it is possible to construct an environment that can be continuously used in experiments through sample exchange and exchange apparatus, and it is effective to minimize the social cost for experiments and research.

The effects of the present invention are not limited to those mentioned above, and other effects not mentioned can be clearly understood by those skilled in the art from the following description.

1 is a view showing a loading slot and a rotating plate according to an embodiment of the present invention.
2 is a perspective view illustrating a reagent replacement apparatus using a detachable low temperature reagent storage jacket according to an embodiment of the present invention.
3 is an enlarged view of a usage section according to an embodiment of the present invention.
4 is a view showing a reagent passing through a cooling section through an inlet and an outlet of a cooling jacket according to an embodiment of the present invention.

BRIEF DESCRIPTION OF THE DRAWINGS The above and other objects, advantages and features of the present invention and methods of achieving them will be apparent from the following detailed description of embodiments thereof taken in conjunction with the accompanying drawings.

The present invention may, however, be embodied in many different forms and should not be construed as being limited to the exemplary embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, And advantages of the present invention are defined by the description of the claims.

It is to be understood that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. In the present specification, the singular form includes plural forms unless otherwise specified in the specification. &Quot; comprises " and / or " comprising ", as used herein, unless the recited component, step, operation, and / Or added.

Prior to describing the preferred embodiments of the present invention, the background of the present invention will be described below in order to facilitate the understanding of those skilled in the art.

In the case of the pump according to the prior art, there are geared, diaphragm, syringe type and the like in various forms.

As a sample exchange device, the sample is supplied through a specific negative pressure pump and piping containing the drug in an open tube.

In the case of conventional pumps, it is necessary to manually replace the specimens after they are put into a container and the use of the containers is completed.

In addition, in order to prevent this, there is a problem that the proposed conventional sample exchange apparatus has a size limitation and it is difficult to control the quantity of the reagent.

Typically, reagents have a limited temperature and shelf life, which makes it difficult to load large quantities, resulting in time loss and material damage due to exchange.

  That is, in order to use the sample exchange apparatus according to the prior art, there is a problem that an additional mechanism, a pump, a valve, and a tubing operation are required.

Reagents should be kept at room temperature, low temperature or freezer depending on the type of reagent. When refrigerated or frozen, they should be stored using a freezer.

Cryopreserved reagents have limited use time, are very sensitive to continuous use, and have very high reagent losses.

In addition, since it is used only once when connected to the pump of the sample exchange apparatus according to the prior art, there is a problem that it is difficult to consecutively use it. Therefore, it is necessary to check every time of replacement, The researcher's fatigue is cumulative, which wastes social costs and poses a serious obstacle to the continuity of the experiment.
FIG. 1 is a view showing a loading slot and a rotating plate according to an embodiment of the present invention. FIG. 2 is a perspective view showing a reagent replacement apparatus using a detachable low temperature reagent storage jacket according to an embodiment of the present invention, FIG. 4 is a view showing a reagent passing through a cooling section through an inlet and an outlet of a cooling jacket according to an embodiment of the present invention. FIG.

delete

According to the embodiment of the present invention, it is possible to use a dedicated hermetically sealed container and an opening container, and the quantity of the loading slots 210a to 210f provided in the rotary plate 200 is controlled according to the quantity of the reagent 100.

That is, by regulating the number of the loading slots 210a to 210f in which the reagents are arranged as required, it is possible to more easily store the reagents having the temperature and the storage time limit.

According to an embodiment of the present invention, the loading slot 210a to 210f including the rotating plate 200 rotatably driven including the loading slots 210a to 210f for loading the reagent 100, And the reagent is supplied to the use section 30 where the syringe pump 400 is disposed.

According to the embodiment of the present invention, the cooling jacket 300, which is a small, thin film type freezing device, is installed in the cooling section 10 and is used for storing only specific reagents.

The cooling jacket 300 is configured to enclose a specific reagent. In the cooling zone 10 where the cooling jacket 300 is disposed, the specific reagent can be stored in a predetermined temperature range.

In FIG. 2, a single reagent is enclosed by the cooling jacket 300. However, it is illustrated by way of example for the purpose of facilitating the understanding of those skilled in the art. It is preferable to set the cooling section 10 to be stored within the range.

The cooling jacket 300 according to the embodiment of the present invention has a configuration capable of adjusting the temperature and is detachably attached, so that the cooling jacket 300 can be freely moved.

4, the cooling jacket 300 includes an inlet 310 through which the reagent 100 required to be cooled is drawn in accordance with the rotation of the rotating plate 200, and a cooled reagent 100 And a discharge part 320 discharged to move to the pump position.

In this case, it is preferable that the inlet portion 310 is formed of an elastic body that narrows the inlet according to the traveling direction of the reagent 100, and the outlet portion 320 is formed of an elastic body that widens the outlet according to the traveling direction of the reagent 100 Do.

As shown in FIG. 3, the syringe pump 400 is disposed in the use zone 30, and provides the reagent 100 when it is necessary to use the reagent 100.

That is, in the reagent replacement apparatus using the detachable low temperature reagent storage jacket according to the embodiment of the present invention, the temperature of the reagent 100 can be easily controlled by using the cooling jacket 300, And the cooling section 10 are continuously provided, it is possible to provide a continuous sample use condition.

The embodiments of the present invention have been described above. It will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims. Therefore, the disclosed embodiments should be considered in an illustrative rather than a restrictive sense. The scope of the present invention is defined by the appended claims rather than by the foregoing description, and all differences within the scope of equivalents thereof should be construed as being included in the present invention.

100: Reagent 200: Spinning plate
300: cooling jacket 400: syringe pump

Claims (5)

The quantity of the reagent is controlled according to the quantity of the reagent, the temperature and the storage period, and the quantity of the reagent is controlled. The loading slot in which the reagent is loaded includes the cooling section, the thawing section and the usage section A rotary plate which continuously moves in a row;
The reagent is stored in a predetermined temperature range and the inlet of the reagent is moved in accordance with the moving direction of the reagent flowing into the cooling section. A detachable cooling jacket including an inlet formed by an increasingly narrow elastic body and an outlet formed by an elastic body whose outlet is gradually widened in accordance with a moving direction of a reagent discharged from the cooling section to the thawing section; And
A syringe pump for performing pumping with respect to the reagent in the use section and providing the reagent to the use section;
A reagent replacement device using a detachable low temperature reagent storage jacket. delete delete delete delete

Images