CN213689650U - Novel many samples autoinjection device - Google Patents

Abstract

A novel multi-sample automatic sampling device comprises a shell, a motion system, a sample loading system, a sampling system, a cutting system and a control system. The utility model discloses advance accurate parallelism good, no cross contamination of appearance, easy operation is convenient, with low costs.

Description

Novel many samples autoinjection device

Technical Field

The utility model belongs to the technical field of the micro-fluidic autoinjection, especially, a novel many samples advance kind autoinjection device is provided.

Background

Microfluidic technology is a technology related to systems for processing and manipulating micro fluids by using micro-pipes, and is widely applied to biological, chemical, medical analysis and other processes. In the microfluidic technology, the sample injection is slow, trace and high in stability requirement, and the sample injection operation of a plurality of samples is often involved; however, a syringe pump or a pressure pump is used as a power source for driving samples, and one syringe pump or one pressure pump can only drive one sample to be injected, so that multi-sample automatic injection is difficult to realize.

Patent document CN110988288A realizes multi-sample sampling through a multi-channel microfluidic switching valve, but it is easy to cause difficulty in cleaning and blockage of the multi-channel microfluidic switching valve, and the switching valve has high cost, especially involving switching over ten samples.

Patent document CN106290953A realizes the control of moving any position of the mechanical gripper in three-dimensional space, accurate positioning, detecting the sample cup to be detected, automatic gripping, moving, and delivering by controlling the X-axis motor, the Y-axis motor, the Z-axis motor, the mechanical gripper motor, etc., and finally realizes automatic sample feeding and continuous detection in multi-sample detection, but the operation of sample feeding is not described, and the function of automatic sample feeding of trace samples cannot be satisfied.

In patent document CN210742287U, automatic sample injection of a trace sample is realized through a motion system, a sample loading system, a sample injection system and a control system, the sample injection mode has high technical requirements on a gun head and a needle head base of the sample injection system, the needle head base and the gun head are used as two independent structures, a completely sealed environment needs to be formed when in use, and once the technical requirements cannot be met or a pipeline of the structure is blocked, the pipeline needs to be replaced, so that the cost is high; in addition, in repeated sample introduction, the gun head and the needle head base are continuously and repeatedly opened and closed to circulate, so that the structure is easily abraded, a closed environment is difficultly maintained, and the risk of bacteria contamination is increased more easily.

Therefore, a controllable multi-sample sampling device is needed, which has the advantages of good sampling accuracy and parallelism, no cross contamination, simple and convenient operation and low cost.

Disclosure of Invention

An object of the utility model is to provide a novel many samples autoinjection device and method realizes the automatic appearance of trace many samples, and it advances a kind and need not pass through special syringe needle or rifle head of advancing, only needs just can realize advancing a kind accurate parallelism good, no cross contamination through the capillary, easy operation convenience, with low costs. Furthermore, the utility model discloses a constant temperature module can also maintain the stability of liquid appearance system in the sample container.

The purpose of the utility model is realized by the following technical scheme.

A novel multi-sample automatic sampling device comprises a shell, a motion system, a sample loading system, a sampling system, a cutting system and a control system, wherein the motion system is used for sample sampling positioning and comprises a switching mechanism I moving along a transverse X axis and an X axis motor thereof, and a switching mechanism II moving along a vertical Z axis and a Z axis motor thereof; the switching mechanism I is fixed on the switching mechanism II; the sample carrying system comprises a rotating motor, a constant temperature module driven by the rotating motor to rotate, and a sample carrying disc arranged on the constant temperature module; the sample introduction system comprises a sample container, a pipeline transmission module and a power source for driving the pipeline liquid to flow; the sample container is placed on the sample carrying disc, and the pipeline transmission module comprises a transmission pipeline pulley, a rolling motor for driving the pulley to roll and a pipeline fixing clamp; the cutting system comprises a blade clamp, a pipe cutting blade and a pipe cutting motor arranged at the end of the blade clamp; the control system is used for controlling each system in the multi-sample automatic sample feeding device.

Preferably, limit switches are arranged on the switching mechanism I, the switching mechanism II, the sample carrying disc and the cutting system.

Preferably, the constant temperature module is a temperature regulating and controlling and heat preserving device, and is a device for heating and cooling and maintaining constant temperature according to the requirement of the sample.

Preferably, the transmission pipeline pulley, the rolling motor for driving the pulley to roll, the pipeline fixing clamp and the pipe cutting motor are all fixed on the fixing plate through mechanical connection.

Preferably, the pipeline is made of a plastic material which can be sterilized by high pressure, moist heat and does not deform, and the inner diameter of the pipeline is 100-2000 microns, and further preferably 900-1100 microns.

Preferably, the pipe is made of any one or more of PA (polyamide), PC (polycarbonate), PS (polystyrene), ABS (acrylonitrile-butadiene-styrene copolymer), PTFE (polytetrafluoroethylene).

Preferably, the pipe cutting blade is 0.3-1.5 cm, preferably 1 cm, from the pipe at normal conditions, i.e. when no cutting operation is performed.

Preferably, the sample carrying disc is a sample carrying disc, and a rotating shaft of the rotating motor and the sample carrying disc are coaxial; the sample carrying disc is provided with a groove or a hole groove structure for positioning and placing a sample bottle; the structure of the grooves or the holes is a plurality of grooves or holes which are arranged around the axes of the rotating motor and the sample loading disc in a rotating mode.

Preferably, the sample introduction power source, the X-axis motor, the Z-axis motor, the rotating motor, the tube cutting motor and the rolling motor all comprise control units for controlling; the sample injection power source control unit is used for adjusting the flow speed and flow of sample injection liquid so as to control the sample injection speed and sample injection amount of the sample liquid; the control unit of the X-axis motor and the Z-axis motor is used for controlling displacement positioning; the rotating motor control unit is used for controlling the sample loading disc to rotate and position; the pipe cutting motor control unit is used for controlling the pipe cutting operation; and the rolling motor control unit is used for controlling the operation of the transmission pipeline.

Preferably, the control system comprises a controller and a PC display control system; the controller respectively controls the control units of the motion system, the sample loading system, the sample feeding system and the cutting system through digital circuits; and the PC display control system displays, stores and analyzes the information of the motion system, the sample loading system and the sample injection system.

Preferably, an operation door is arranged on the shell, and a transparent observation window is arranged on the operation door.

Preferably, an independent sealed environment is formed in the shell to form an operation chamber, and an ultraviolet sterilizing lamp is arranged in the shell 1 of the operation chamber, so that a sterile operation environment is formed.

Preferably, an ultraviolet lamp switch, a complete machine switch, a USB interface and a power supply interface are arranged on the side portion of the shell 1.

A sampling method of a novel multi-sample automatic sampling device comprises the following steps:

the first step, sample adding: adding samples into all sample containers, and covering the sample containers with liquid media which is not compatible with the samples and is used for isolation;

a second step of positioning the lower tube: the pipeline port corresponds to the sample bottle by rotating the motor and/or the switching mechanism I, and then the switching mechanism II and the rolling motor transmit the pipeline to regulate and control operation, so that the pipeline enters the liquid medium of the sample container;

step three, exhausting gas and injecting sample: the sample injection power source drives the gas in the discharge pipeline and then drives the liquid medium to enter the pipeline; the switching mechanism II moves downwards to enable the port of the pipeline to be positioned in the sample, and the sample introduction power source drives the sample to enter the pipeline; the switching mechanism II moves upwards to enable the opening of the pipeline to be positioned in the liquid medium, and the sample injection power source drives the liquid medium to enter the pipeline to form micro liquid drops of one medium and the other medium;

a fourth step of cutting the tube: the switching mechanism II moves upwards to enable the pipeline port to be positioned above the sample bottle, and the pipe cutting motor drives the blade to cut the pipe;

and fifthly, repeating the operations of the second step to the fourth step, and repeating sample injection or completing next new sample injection to finally complete multi-sample injection.

In one embodiment, the sample bottle is filled with a sample and liquid medium in a volume ratio of 1:2 to 3: 1.

In one embodiment, the volume of the micro sample introduced in the third step is 0.5 to 10. mu.l, preferably 0.6 to 8. mu.l, more preferably 0.7 to 7. mu.l, more preferably 0.8 to 6. mu.l, more preferably 0.9 to 5. mu.l, and more preferably 1 to 3. mu.l.

In one embodiment, the sample bottle is adapted to hold a liquid volume of 0.5-10 mL, preferably 1-5 mL, and more preferably 1-2 mL.

In one embodiment, the loading tray is provided with 1-100 grooves or wells, preferably 5-50, and more preferably 15-40.

Preferably, a chip structure is arranged between the pipeline and the sample feeding power source, so that formed micro liquid drops can be identified and detected in the chip.

Compared with the prior art, the utility model has the advantages that one sample introduction power source is adopted to realize automatic sample introduction of multiple samples, thereby avoiding the sampling difference caused by different sampling power sources and pipelines and reducing the error among the samples; the repeated automatic sample introduction of the sample micro-pipeline is realized by adopting a pipeline cutting mode, so that the contamination is effectively avoided, the cross contamination among different samples is avoided, the cost is saved, and the operation is simple; through setting up the constant temperature module, sample constant temperature control.

The above description is only an overview of the technical solutions of the present invention, and in order to make the technical means of the present invention more clearly understood, the technical means of the present invention is implemented to the extent that those skilled in the art can implement the technical solutions according to the description, and in order to make the above and other objects, features, and advantages of the present invention more obvious and understandable, the following description is given by way of example of the embodiments of the present invention.

Drawings

Various other advantages and benefits of the present invention will become apparent to those of ordinary skill in the art upon reading the following detailed description of the preferred embodiments. The drawings are only for purposes of illustrating the preferred embodiments and are not to be construed as limiting the invention. It is obvious that the drawings described below are only some embodiments of the invention, and that for a person skilled in the art, other drawings can be obtained from these drawings without inventive effort. Also, like parts are designated by like reference numerals throughout the drawings.

In the drawings:

FIG. 1 is a schematic structural view of the multi-sample automatic sampling device of the present invention;

FIG. 2 is a perspective view of an embodiment of the multi-sample autosampler of the present invention;

FIG. 3 is an internal structure diagram of the multi-sample automatic sampling device of the present invention;

FIG. 4 is a perspective view of another embodiment of the multi-sample autosampler of the present invention;

fig. 5 is a schematic view of a local amplification of an embodiment of the cutting system of the multi-sample automatic sampling device of the present invention.

FIG. 6 is a schematic view of the sample feeding system of the cutting system of the automatic multi-sample feeding device of the present invention;

description of the symbols:

1 shell 2 movement system 21 switching mechanism I22 switching mechanism II

3 carry appearance system 31 and carry appearance dish 32 constant temperature module 33 rotating electrical machines

4 sample introduction system 41, sample container 42, pipeline 43, pipeline transmission module 44 and sample introduction power source

5 cutting system 51 blade anchor clamps 52 pipe cutting blade 53 pipe cutting motor

6 control system 7 operating room door 8 observation window 9 operating room 10 ultraviolet sterilizing lamp

11 pipeline channel 12Z-axis motor 13X-axis motor 14 transmission pipeline pulley

15 rolling motor 16 that drive pulley is rolling fixes plate 17 pipeline fixation clamp

111 ultraviolet lamp switch 112, complete machine switch 113, USB interface 114, power interface.

Detailed Description

Specific embodiments of the present invention will be described in more detail below with reference to the accompanying drawings. While specific embodiments of the invention are shown in the drawings, it will be understood that the invention may be embodied in various forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the invention to those skilled in the art.

It should be noted that certain terms are used throughout the description and claims to refer to particular components. As one skilled in the art will appreciate, various names may be used to refer to a component. This specification and claims do not intend to distinguish between components that differ in name but not function. In the following description and in the claims, the terms "include" and "comprise" are used in an open-ended fashion, and thus should be interpreted to mean "include, but not limited to. The following description is of the preferred embodiment of the invention, and is made for the purpose of illustrating the general principles of the invention and not for the purpose of limiting the invention. The protection scope of the present invention is subject to the limitations defined by the appended claims.

To facilitate understanding of the embodiments of the present invention, the following description will be given by way of example of several specific embodiments with reference to the accompanying drawings, and each of the drawings does not constitute a limitation of the embodiments of the present invention.

Specifically, as shown in fig. 1 and fig. 2, the utility model discloses a novel multi-sample automatic sampling device, which comprises a housing 1, a motion system 2, a sample carrying system 3, a sampling system 4, a cutting system 5, and a control system 6; the motion system 2 is used for sample feeding and positioning, and comprises a switching mechanism I21 moving along a transverse X axis and an X axis motor 13 thereof, and a switching mechanism II 22 moving along a vertical Z axis and a Z axis motor 12 thereof; the switching mechanism I21 is fixed on the switching mechanism II 22; the sample carrying system 3 comprises a rotating motor 33, a constant temperature module 32 driven by the rotating motor to rotate, and a sample carrying disc 31 arranged on the constant temperature module; the sample introduction system 4 comprises a sample container 41, a pipeline 42, a pipeline transmission module 43, and a power source 44 for driving the pipeline to flow; the sample container 41 is placed on the sample loading plate 31, and the pipeline transmission module 43 comprises a transmission pipeline pulley 14, a rolling motor 15 for driving the pulley to roll and a pipeline fixing clamp 17; the cutting system comprises a blade clamp 51, a pipe cutting blade 52 and a pipe cutting motor 53 arranged at the end of the blade clamp; and the control system 6 is used for controlling each system in the multi-sample automatic sample feeding device.

In one embodiment, the switching mechanism I21 and the switching mechanism II 22 are respectively provided with a limit switch. Specifically, in order to implement automatic control, the X-axis motor 13 and the Z-axis motor 12 further include a control unit for controlling the movement of the switching mechanism I21 and the switching mechanism II 22, and the control unit receives an externally input displacement signal and controls the corresponding limit switch, so as to control the state of the corresponding motor and adjust the specific displacement.

In a specific embodiment, the constant temperature module 32 is a temperature regulating and maintaining device, which heats or cools according to the needs of the sample, and is provided with a sample loading tray 31. The utility model discloses the shape of well constant temperature module does not do the injeciton, only need can satisfy the heating or cool down and maintain homothermal function can. As shown in fig. 3, the sample-carrying plate 31 is provided with one or more grooves or hole-groove structures for accommodating sample containers; the recess or well is circular or otherwise shaped to conform to the configuration of the sample container and serves to prevent the sample container from tipping and/or shifting. The shape of the sample container is not particularly limited, and it is used to contain a liquid volume of 0.5 to 10 mL, preferably 1 to 5 mL, further preferably 1 to 2 mL; wherein the volume ratio of the liquid medium for isolation for containing the sample and being immiscible with the sample is 1: 2. The shape of the grooves or the grooves can be any shape, but all the grooves or the grooves are orderly and rotationally arranged around the axes of the rotating motor 33 and the sample carrying disc 31, so that the pipeline 42 and the sample container 41 can be conveniently and accurately positioned through the displacement of the switching mechanism I21 and the switching mechanism II 22.

In one embodiment, the plate 31 is a plate that rotates with the rotating motor 33. Furthermore, the grooves or the hole grooves are circular, and the distances from the circle centers of the circular grooves or the hole grooves to the circle center of the sample loading disc are equal. The distance is not further limited, and only a sample container can be reasonably placed to facilitate equidistant sampling; in addition, the center of the sample loading disc can also be provided with a groove or hole groove structure.

In one embodiment, the sample carrier 31 is also provided with a limit switch. In a specific embodiment, the utility model discloses in be provided with the rotating electrical machines control unit, it carries the rotation of appearance dish through direct control or adopt limit switch indirect control, realizes that automatic control carries the accurate location of sample container 41 and pipeline 42 in the appearance dish 31.

In an embodiment of the present invention, the pipe 42 is made of a plastic material that can be sterilized by high pressure and moist heat without deformation, preferably any one or more of PA (polyamide), PC (polycarbonate), PS (polystyrene), ABS (acrylonitrile-butadiene-styrene copolymer), and PTFE (polytetrafluoroethylene). In order to meet the requirement of micro-sampling, the inner diameter of the pipeline is 100-2000 microns, and preferably 900-1100 microns. The liquid flow of the pipeline 42 depends on the sample injection power source 44 connected with the other end of the pipeline and used for driving the pipeline to flow, and the sample injection power source 44 needs to realize high-precision and smooth pulse-free liquid transmission. In particular embodiments, sample power source 44 may be a syringe pump, a peristaltic pump, a diaphragm pump, and/or a plunger pump, preferably a syringe pump. The utility model discloses in, to advancing the range size of appearance power supply 44 and not injecing, syringe pump, peristaltic pump, diaphragm pump and/or the plunger pump of suitable range can rationally be selected to the needs according to the sample appearance to the personnel in this field.

In order to realize the accurate control to the sample propelling movement, the power supply still includes the control unit who is used for controlling the appearance of advancing. The control unit receives an externally input sample introduction signal comprising a sample introduction speed and a sample introduction amount, outputs a control signal, controls the driving of the power source, and adjusts the flow speed and the flow of the liquid entering the culture pipeline so as to control the sample introduction speed and the sample introduction amount of the solution.

The utility model discloses well pipeline 42 is fixed a position by pipeline fixation clamp 17, the pipeline fixation clamp comprises two or more, and the position of pipeline fixation clamp 17 is not injectd, as long as can the fixed pipeline not remove at will. The transmission of the pipeline 42 is controlled by a transmission pipeline pulley 14 and a rolling motor 15 for driving the pulley to roll. In order to make the internal structure reasonable arranged and designed, the transmission pipeline pulley 14, the rolling motor 15 and the pipeline fixing clamp 17 are arranged on the fixing plate 16, as shown in fig. 3, the pipeline fixing clamp 17 and the transmission pipeline pulley 14 are arranged at the front end of the fixing plate 16, and the rolling motor 15 is arranged at the rear end of the fixing plate 16. The transmission length of the pipeline 42 can be the same or different, the transmission length is controlled by the rolling motor 15, and in order to realize automatic control, a control unit is arranged on the rolling motor 15 to accurately control the pipeline transmission operation, so that the length of the pipeline at each time meets the sampling requirement.

The utility model discloses a on the casing, leave pipeline channel 11, pipeline channel 11 mouth can be big or small, as long as can realize that the pipeline freely passes through can. As shown in fig. 4, the duct channel 11 is further provided with an upper cover.

In one embodiment, as shown in fig. 5, the pipe 42 is cut by controlling the blade clamp 51 and further controlling the pipe cutting blade 52 to move and cut by the pipe cutting motor 53, and the moving manner is not limited, and the pipe can be cut by moving back and forth or left and right, as long as the pipe 42 can be cut effectively. In one embodiment, the tube cutting motor 53 is mounted on the stationary plate 16 and the tube cutting blade 52 is spaced 0.3-1.5 cm, preferably 1 cm, from the pipe. The utility model discloses in, be provided with cutting system's limit switch, it controls blade anchor clamps 51 displacement, makes pipe cutting blade 52 accomplish pipeline 42 automatic cutout.

In one embodiment, the control system 6 includes a controller and a PC display control system; the controller respectively controls the control units of the motion system 2, the sample loading system 3, the sample feeding system 4 and the cutting system 5 through digital circuits; and the PC display control system displays, stores and analyzes the information of the motion system 2, the sample loading system 3 and the sample injection system 4.

In a specific embodiment, be provided with operation room door 7 on the casing, be provided with transparent observation window 8 on the operation room door 7, moving system 2, year appearance system 3, sampling system 4, cutting system 5, control system 6 set up in the casing, place or change sample container 41 and go on in operation room 9 through opening operation room door 7, and operation room 9 forms independent sealed environment, is favorable to avoiding the contamination, is provided with ultraviolet sterilizing lamp 10 inside operation room 9 casing 1 for maintain sterile environment. An ultraviolet lamp switch 111, a complete machine switch 112, a USB interface 113 and a power interface 114 are arranged on the side of the shell 1; the ultraviolet lamp switch 111 is used for controlling the ultraviolet sterilizing lamp 10, the complete machine switch 112 controls the state of the complete machine switch in a one-key mode, the USB interface 113 is used for exchanging information with an external power supply, and the power supply interface 114 is used for connecting the external power supply. At least 4 foundation bolts are arranged on the ground of the shell 1 and used for controlling the shell to keep balance.

The utility model relates to a novel many samples give a good luck the appearance method of device, it includes:

the first step, sample adding: all sample containers are filled with the sample, which is covered with a liquid medium for isolation that is immiscible with the sample.

In a specific embodiment, the sample is a liquid sample, and the liquid medium is selected from an oil phase, and further preferably silicone oil, fluorinated oil, mineral oil, and the like; the sample is preferably a water sample, and further is a sample containing one or more of culture factor components and microorganisms; the oil phase was immiscible with the sample. The volume ratio of the sample to the oil phase added into the sample bottle is 1:2 to 3:1, the sample is not dissolved with the oil phase, the density of the sample liquid is greater than that of the oil phase, and the oil phase covers the upper part of the sample liquid below the sample bottle, so that the sample can be isolated, and the sample pollution can be avoided. The sample bottle is used for containing liquid with the volume of 0.5-10 mL, preferably 1-5 mL, and further preferably 1-2 mL; the volume ratio of the contained oil to the water is 1: 2.

A second step of positioning the lower tube: the pipeline port corresponds to the center of the sample bottle by rotating the motor and/or the switching mechanism I, and then the switching mechanism II and the rolling motor transmit the pipeline to regulate and control operation, so that the pipeline enters the oil phase of the sample container.

In one embodiment, the switching mechanism I translates, and the rotating motor fine-tunes to make the mouth of the pipe correspond to the center of the sample bottle, the operation of the rolling motor transmission pipe can be set according to a preset program, and before or after the switching mechanism II moves downwards, the pipe is finally made to a preset length to enter the oil phase of the sample container. The length of the pipeline is controlled by the transmission of a rolling motor.

Step three, exhausting gas and injecting sample: the sample injection power source drives the gas in the discharge pipeline and then drives the liquid medium to enter the pipeline. The conduit is filled with a liquid medium prior to use; the inner diameter of the interconnected pipes is 10 micrometers to 5 mm, preferably 50 micrometers to 2 mm, further preferably 500 micrometers to 1.5 mm, and preferably 800 micrometers to 1.2 mm. The switching mechanism II moves downwards to enable the pipeline port to be positioned in the middle of the sample, and the sample introduction power source drives the sample to enter the pipeline; the switching mechanism II moves upwards to enable the mouth of the pipeline to be positioned in the liquid medium of the sample container, and the sample introduction power source drives the liquid medium to enter the pipeline to form micro liquid drops of one medium for isolating the other medium; .

In one embodiment, the step is repeated to achieve multiple injections of the sample, and the microdroplets are formed as a plurality of water-in-oil microdroplets. The volume of the sample is 0.5-10 μ l, preferably 0.6-8 μ l, more preferably 0.7-7 μ l, even more preferably 0.8-6 μ l, even more preferably 0.9-5 μ l, even more preferably 1-3 μ l. Wherein the sample injection volume of the oil phase is 1-3 times of that of the sample.

A fourth step of cutting the tube: the switching mechanism II moves upwards to enable the pipeline port to be positioned above the sample bottle, and the pipe cutting motor drives the blade to cut the pipe.

And fifthly, repeating the operations of the second step to the fourth step, and repeating sample injection or completing next new sample injection to finally complete multi-sample injection.

In order to facilitate the sampling control of operators, the device also comprises a controller and a PC display control system which are used for inputting and controlling various operation parameters, such as exhaust time, sample input quantity and sampling times, oil phase input quantity and sampling times and the like.

The utility model discloses a multi-sample introduction method, only need to load liquid in the sample bottle and put it into the groove or hole groove correspondingly, utilize one to advance a kind power supply and just can realize multi-sample autoinjection, avoid through the different sample power supply and the pipeline caused sample difference, reduce the error between the samples; the repeated automatic sample introduction of the sample micro-pipeline is realized by adopting a pipeline cutting mode, so that the contamination is effectively avoided, the cross contamination among different samples is avoided, the cost is saved, and the operation is simple; and controlling the temperature of the sample by arranging a constant temperature module.

Industrial applicability

The utility model discloses a many samples autoinjection device and application method can make and use in high flux microorganism cultivation field, especially cooperates a little liquid drop processing apparatus (publication number 110579616A) to use.

Although the embodiments of the present invention have been described above with reference to the accompanying drawings, the present invention is not limited to the above-described embodiments and application fields, and the above-described embodiments are illustrative, instructive, and not restrictive. Those skilled in the art, having the benefit of this disclosure, may effect numerous modifications thereto without departing from the scope of the invention as defined by the appended claims.

Claims (10)

1. The utility model provides a novel many samples autoinjection device which characterized in that: comprises a shell, a motion system, a sample loading system, a sample feeding system, a cutting system and a control system, wherein,

the motion system is used for sample feeding and positioning and comprises a switching mechanism I moving along a transverse X axis and an X axis motor thereof, and a switching mechanism II moving along a vertical Z axis and a Z axis motor thereof; the switching mechanism I is fixed on the switching mechanism II;

the sample carrying system comprises a rotating motor, a constant temperature module driven by the rotating motor to rotate, and a sample carrying disc arranged on the constant temperature module;

the sample introduction system comprises a sample container, a pipeline transmission module and a power source for driving the pipeline liquid to flow; the sample container is placed on the sample carrying disc, and the pipeline transmission module comprises a transmission pipeline pulley, a rolling motor for driving the pulley to roll and a pipeline fixing clamp;

the cutting system comprises a blade clamp, a pipe cutting blade and a pipe cutting motor arranged at the end of the blade clamp;

the control system is used for controlling each system in the multi-sample automatic sample feeding device.

2. The device of claim 1, wherein limit switches are disposed on the switching mechanism I, the switching mechanism II, the sample loading plate and the cutting system.

3. The apparatus of claim 1, wherein the transmission pipeline pulley, the rolling motor for driving the pulley to roll, the pipeline fixing clamp and the pipe cutting motor are fixed on the fixing plate through mechanical connection.

4. The device as claimed in claim 1, wherein the tube is made of a plastic material which can be sterilized by high pressure, moist heat and is not deformed, and the inner diameter of the tube is 100-2000 μm.

5. The apparatus of claim 1, wherein said pipe cutting blade is normally spaced from said pipe by 0.3-1.5 cm when not in use.

6. The apparatus of claim 1, wherein the sample carrier disk is a sample carrier disk having a plurality of grooves or slot structures disposed thereon.

7. The apparatus of claim 6, wherein the grooves or slots are arranged in a plurality that are rotatable about the axis of the rotation motor and the sample-carrying disk.

8. The device of claim 1, wherein the sample feeding power source, the X-axis motor, the Z-axis motor, the rotating motor, the tube cutting motor and the rolling motor comprise control units for controlling.

9. The apparatus of claim 8, wherein the control system comprises a controller and a PC display control system; the controller respectively controls the control units of the motion system, the sample loading system, the sample feeding system and the cutting system through digital circuits; and the PC display control system displays, stores and analyzes the information of the motion system, the sample loading system and the sample injection system.

10. The device as claimed in claim 1, wherein the housing is provided with an operating room door with a transparent viewing window, the inner wall of the housing is provided with an ultraviolet sterilizing lamp, and the side wall of the housing is provided with an ultraviolet lamp switch, a complete machine switch, a USB interface and a power supply interface.

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