KR101905067B1

KR101905067B1 - Analysis method of single breath and analysis device of single breath

Info

Publication number: KR101905067B1
Application number: KR1020160159996A
Authority: KR
Inventors: 이동규; 권오원; 이강호; 김창원; 이명환
Original assignee: 한국기계연구원
Priority date: 2016-11-29
Filing date: 2016-11-29
Publication date: 2018-10-05
Also published as: KR20180060469A; WO2018101650A1

Abstract

The present invention relates to a method and an apparatus for analyzing a single breathing gas capable of accurately analyzing biogas contained in a respiratory gas by a single breath and monitoring respiratory diseases of a patient through the analyzed biogas .
For this purpose, the single breathing gas analysis method detects the peak velocity of the respiratory gas and the humidity of the respiratory gas generated through the single breath and detects the biogas contained in the respiratory gas according to the user's disease using the biosensor A first detection value correction step of removing a influence of the peak speed and the humidity on the biosensor from the detection value detected by the corresponding biosensor to obtain a detection correction value; A second detection value correction step of removing the influence of biogas other than the biogas on the biosensor to obtain a gas correction value, and a concentration calculation step of calculating the concentration of the biogas using the gas correction value .

Description

TECHNICAL FIELD [0001] The present invention relates to a method and an apparatus for analyzing single breathing gas,

The present invention relates to a method and an apparatus for analyzing single breathing gas, and more specifically, it is possible to accurately analyze biogas contained in a respiratory gas by a single breath alone, and to monitor respiratory diseases of a patient through the analyzed biogas The present invention relates to a method and an apparatus for analyzing a single respiratory gas.

Gas sensors have been used for a variety of purposes, starting from the use for alarming the leakage of traditional hazardous gases and, in recent years, by constantly measuring the state of the atmospheric environment. Recently, much attention has been paid to the technique of acquiring biometric information by measuring various biogas contained in respiratory gases.

Gases, such as volatile organic compounds and volatile sulfur compounds, emitted through exhaled breath, reach hundreds of species, of which specific gases include life information It is known that it can be used as a biomarker.

In particular, continuous respiratory gas monitoring is required for reasons such as chronic respiratory diseases (chronic obstructive pulmonary disease, asthma, pneumonia, etc.) or prognosis of lung cancer surgery. In this case, the respiratory gas analyzer to which the gas sensor is applied can be used simply and noninvasively to minimize radiation exposure due to computed tomography and x-ray imaging.

However, since respiratory gas is generally a mixed gas environment, the corresponding gas sensor for detecting the corresponding biogas in a mixed gas environment is affected by biogas other than the biogas, so that its practical use is limited.

In addition, general respiratory gas analysis equipment has been developed using separate pump means for injecting respiratory gas at a constant rate, or using separate moisture removal means to remove the moisture contained in respiratory gases.

Korean Patent Publication No. 10-2015-0024299 (entitled " Collection and Analysis of Exhaust Gas Volume Using Compensation of Respiratory Variables Frequency)

SUMMARY OF THE INVENTION An object of the present invention is to solve the conventional problems, and it is an object of the present invention to provide an apparatus and method for analyzing a biogas contained in a respiratory gas, And a method and apparatus for analyzing respiratory gas.

According to another aspect of the present invention, there is provided a method for analyzing a single breathing gas, comprising: detecting a peak velocity of respiratory gas generated through a single breath and a humidity of the respiratory gas; A detection step of detecting a biogas contained in the respiratory gas according to a user's disease using the biogas; A first detection value correction step of removing the influence of the peak velocity and the humidity on the biosensor from the detection value detected by the biosensor to obtain a detection correction value; A second detection value correction step of removing the influence of biogas other than the biogas on the biosensor from the detection correction value calculated for the biogas to obtain a gas correction value; And a concentration calculating step of calculating a concentration of the biogas using the gas correction value.

Here, the biogas may include a first biogas and a second biogas, the biosensor may include a first biosensor for detecting the first biogas, a second biosensor for detecting the second biogas, .

Then, the second detection value correction step corrects the second detection value based on the first detection correction value calculated for the first biogas among the detection correction values, Wherein the second biosensor calculates a first gas primary correction value by applying a first coefficient to the first biosensor, A first correction step of calculating a second gas primary correction value by applying a gas primary correction coefficient; Calculating a first gas secondary correction value by applying a first gas secondary correction coefficient that the second biogas applies to the first biosensor based on the second gas primary correction value at the first detection correction value A second correction step of correcting the first correction value; And a first correction value comparison step of comparing a first gas first error between the first gas secondary correction value and the first gas primary correction value with a predetermined first gas error range, 1 gas first error is included in the predetermined first gas error range, the concentration calculating step is performed based on the first gas secondary correction value.

Here, when the first gas first error exceeds the predetermined first gas error range through the first correction value comparison step, in the second correction step, the first gas first correction Calculating a second gas secondary correction value by applying a second gas secondary correction coefficient of the first biogas to the second biosensor based on the first biogas value, A first gas j-th correction coefficient applied to the first biosensor by the second biogas on the basis of a second gas j-1th correction value (j is a constant increasing from 3) A third correction step of calculating a gas j-th correction value; And a second correction value comparison step of comparing the first gas j-1 difference error between the first gas j-order correction value and the first gas j-1 correction value with a predetermined first gas error range , And when the first gas j-1 order error is included in the predetermined first gas error range through the second correction value comparison step, the concentration calculating step is performed based on the first gas j-order correction value do.

Here, if the first gas j-1 order error deviates from the predetermined first gas error range through the second correction value comparison step, the third correction step and the second correction value comparison step are repeated.

The method of analyzing a single breathing gas according to the present invention further includes a concentration comparing step of comparing the concentration with a predetermined reference concentration corresponding to the biogas, and comparing the concentration to a preset reference concentration If not, the user is informed of the abnormal findings of the medical findings corresponding to the concentration.

The analysis apparatus of the single breathing apparatus according to the present invention includes: an analysis body having a straight type delivery pipe through which a respiratory body generated through a single breath is delivered; At least two biosensors for detecting the biogas contained in the respiratory gas in accordance with a disease of the user, the biosensors being arranged in a direction in which the respiratory organ is transported in the transport pipe according to the type of the biogas to be detected; A pressure sensor provided on the side of the discharge pipe through which the respiratory organ is discharged from the transfer pipe and detecting a pressure of the respiratory gas to obtain a peak velocity of the respiratory gas; A humidity sensor provided at one side of the biosensor or the pressure sensor for detecting the humidity of the respiratory gas; And obtaining a peak velocity of the respiratory gas on the basis of the detected pressure of the respiratory gas and detecting the influence of the peak velocity and the humidity on the biosensor from the detection value detected by the corresponding biosensor, And a control unit for removing the influence of other biogas on the biosensor and then calculating the concentration of the biogas.

The apparatus for analyzing a single breathing gas according to the present invention further includes an exhaust plug provided at the exhaust port and having a plurality of exhaust holes formed therethrough, wherein the exhaust plug detects the pressure of the respiratory gas by the pressure sensor A closed region in which the discharge hole is not formed corresponding to an area where the discharge hole is formed; And a discharge area in which the discharge hole is formed.

Here, the control unit may include: a peak-velocity obtaining unit that obtains a peak velocity of the respiratory gas based on the pressure detected by the pressure sensor; A first detection value determining unit for obtaining a detection correction value by removing the influence of the peak speed and the humidity on the biosensor from the detection value detected by the corresponding biosensor; A second detection value boration unit for removing the influence of biogas other than the biogas on the biosensor from the detection correction value calculated for the biogas to obtain a gas correction value; And a concentration calculating unit for calculating a concentration of the biogas using the gas correction value.

The control unit may further include a concentration ratio issuing unit for comparing the concentration with a preset reference concentration corresponding to the biogas. When the concentration is not included in the predetermined reference concentration corresponding to the biogas, And informs the user of abnormal medical findings corresponding to the concentration.

The apparatus for analyzing single breathing gas according to the present invention is characterized in that the biosensor, the pressure sensor and the humidity sensor are operated so that the biosensor, the pressure sensor and the humidity sensor are operated in a state in which the respiratory organ is absent before the respiratory organ passes through the transfer tube. And an initialization button for initializing the detected value of the humidity sensor.

The apparatus for analyzing single breathing gas according to the present invention is characterized in that the detection values of the biosensor, the pressure sensor and the humidity sensor are set to "0" so that the influence of the outside air flowing into the transfer tube is removed after the initialization button is operated And a zero button for setting.

According to the method and apparatus for analyzing single breathing gas according to the present invention, it is possible to accurately analyze the biogas contained in the respiratory gas by only a single breath, and to monitor the respiratory disease of the patient through the analyzed biogas have.

In addition, the present invention does not require separate pump means or separate moisture removing means in a mixed gas environment of respiratory gas containing a large amount of water in analyzing or monitoring the respiratory gas, The error of the result can be minimized.

In addition, the present invention corrects the detection value of the corresponding biosensor detecting the corresponding biogas even by a single breath, using a complex correction algorithm, so that the peak velocity of the respiratory gas affecting the biosensor in the complex gas environment, the humidity of the respiratory gas, It is possible to eliminate the influence of the biogas other than the biogas on the biosensor and accurately calculate the concentration of the biogas even in a complex gas environment.

In addition, the present invention applies a specific correction coefficient to the biosensor on the influence of biogas other than the biogas on the biosensor, confirms convergence between the correction values to which the correction coefficient is applied, The accuracy of the concentration calculation of the biogas can be improved by accurately correcting the detection value detected by the sensor.

In addition, the present invention improves the linkage with the target disease in response to the concentration of the biogas, and can predict the disease of the user.

In addition, the present invention uses a single-type transfer tube formed of a single suction port and a single discharge port, so that the maximum flow rate, respiration rate and humidity of the respiratory gas for single breathing can be reduced Can be accurately detected.

Further, the present invention shows an amplifying effect of a detection value detected through a pressure sensor according to the configuration of an exhaust cap, minimizes a detection error of a detection value detected through a pressure sensor, and accurately obtains a peak velocity of a respiratory gas have.

In addition, the present invention can prevent the detection error of the sensors through the initialization button, acquire environment information around the analyzer through each of the sensors, and reduce an error based on environmental information.

Further, according to the present invention, the initial value of the sensors can be set to "0" through the zero button, and the precision of the detection value detected by the sensors can be improved on the basis thereof.

1 is a view illustrating a method of analyzing a single breathing gas according to an embodiment of the present invention.
2 is a graph illustrating an example of a detection value detected by a humidity sensor according to single breathing in the method of analyzing single breathing gas according to an embodiment of the present invention.
3 is a graph illustrating an example of a detection value detected by a biosensor according to a single breath in the method for analyzing single breathing gas according to an embodiment of the present invention.
FIG. 4 is a graph showing an example of the standardized values detected by the humidity sensor and the biosensor with respect to the peak velocity of the respiratory gas in the single breathing gas analysis method according to the embodiment of the present invention.
5 is a view illustrating an apparatus for analyzing single breathing gas according to an embodiment of the present invention.
6 is a view showing an exhaust cap in an apparatus for analyzing single breathing gas according to an embodiment of the present invention.
7 is a view showing a control unit in an apparatus for analyzing single breathing gas according to an embodiment of the present invention.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Reference will now be made in detail to embodiments of the present invention, examples of which are illustrated in the accompanying drawings. Here, the present invention is not limited or limited by the examples. Further, in describing the present invention, a detailed description of well-known functions or constructions may be omitted for clarity of the present invention.

Hereinafter, a method for analyzing a single breathing gas according to an embodiment of the present invention will be described.

FIG. 1 is a view illustrating a method of analyzing a single breathing gas according to an embodiment of the present invention. FIG. 2 is a flowchart illustrating a method of analyzing a single breathing gas according to an exemplary embodiment of the present invention. FIG. 3 is a graph showing an example of a detection value detected by a biosensor according to a single breath in an analysis method of single breathing gas according to an embodiment of the present invention, FIG. 4 is a graph showing an example of a detection value FIG. 2 is a graph showing an example of a standardized value detected by a humidity sensor and a biosensor with respect to a peak velocity of respiratory gas in a single breathing gas analysis method according to an embodiment of the present invention. FIG.

1 to 4, a method for analyzing single breathing gas according to an embodiment of the present invention includes a detecting step, a first detecting value correcting step, a second detecting value correcting step, and a concentration calculating step , And a concentration comparison step.

In one embodiment of the present invention, the peak velocity of the respiratory gas generated through the single breath using the pressure sensor 30, the humidity sensor 40, and the three biosensors, the humidity of the respiratory gas, (NO gas, H2S gas, and VOCs gas) contained in the biogas are detected, and the concentrations of the three biogas are detected based on the detected biogas.

Accordingly, the biosensor 20 can be divided into a first sensor 21 for detecting NO gas, a second sensor 22 for detecting H2S gas, and a third sensor 23 for detecting VOCs gas. have.

The detection step S1 is a step of acquiring a peak velocity of respiratory gas generated through a single breath, detecting the humidity of the respiratory gas, and using the biosensor 20, Biogas is detected.

Here, the peak velocity of the respiratory gas is obtained on the basis of the pressure of the respiratory gas detected through the pressure sensor 30. By monitoring the maximum respiration rate according to the pressure of the respiratory gas, the linearity of the breathing rate of the respiratory gas can be improved. Then, the peak velocity of the respiratory gas can be obtained at the respiration velocity of the respiratory gas in accordance with the monitoring, and the respiration rate for the single respiration can be obtained by integrating the respiration velocity of the respiratory gas. Accordingly, the peak velocity may be a predetermined value according to the pressure detected through the pressure sensor 30, or may be obtained in a separate calculation formula according to the pressure, and may be stored in a data storage unit 56 described later .

The values detected by the first sensor 21, the second sensor 22 and the third sensor 23 are generally positive according to the peak speed and the influence of the humidity, In the case of the value detected by the first sensor 21, it may also be a negative value depending on the influence of the peak speed and the humidity.

Accordingly, the detection value detected by the humidity sensor 40 is selected according to the single breath as shown in FIG. 2, and may be selected as the maximum value among the values detected through the humidity sensor 40.

The detection value detected by the first sensor 21 is selected according to the single breath as shown in FIG. 3 (a). If the lowest value among the values detected through the first sensor 21 is negative If the minimum value is positive, the maximum value can be selected.

Also, the detection value detected by the second sensor 22 is selected according to the single breath as shown in FIG. 3 (b), and is selected as the maximum value among the values detected through the second sensor 22 .

3 (c), the detection value detected by the third sensor 23 is selected according to the single breath, and the maximum value among the values detected through the third sensor 23 is selected .

The detection values detected by the respective sensors via the detection step S1 are stored in a data storage unit 56 described later.

The first detection value correction step (S2) removes the influence of the peak speed and the humidity on the biosensor from the detection value detected by the corresponding biosensor to obtain a detection correction value.

The detection correction value for the biosensor will now be described.

Vno (0) = Vno (B) - Vno (H, F)

Vh2s (0) = Vh2s (B) - Vh2s (H, F)

Vvoc (0) = Vvoc (B) - Vvoc (H, F)

Here, "=" represents an equal sign, and "-" represents subtraction.

In addition, Vno (0) is a detection correction value for the detection value detected by the first sensor 21, Vh2s (0) is a detection correction value for the detection value detected by the second sensor 22, Vvoc (0) is a detection correction value for the detection value detected by the third sensor 23. [

Vo2 (B) is a detection value detected by the first sensor 21, Vh2s (B) is a detection value detected by the second sensor 22, and Vvoc (B) 23).

Further, H is the humidity component and F is the peak velocity component. Then, Vno (H, F) is the influence of the detected peak velocity and the humidity on the first sensor 21, and Vh2s (H, F) Vvoc (H, F) is the influence of the detected peak velocity and humidity on the third sensor 23. At this time, Vno (H, F), Vh2s (H, F) and Vvoc (H, F) are preset values according to the correlation between the peak velocity and the humidity, And stored. Vno (H, F), Vh2s (H, F) and Vvoc (H, F) generally show a large correction amount for the humidity.

The detection correction values for the corresponding biosensors calculated through the first detection value correction step S2 are stored in a data storage unit 56 described later.

The second detection value correction step (S3) obtains a gas correction value by removing the influence of biogas other than the biogas on the biosensor from the detection correction value calculated for the biogas.

The second detection value correction step S3 may include a first correction step S31, a second correction step S32, and a correction value comparison step.

In the first correction step (S31), a primary correction value is calculated by applying a primary correction coefficient, which is different from the biogas other than the biogas, to the biogas, from the detection correction value calculated for the biogas.

More detail. The first correction step (S31) may include applying a first gas first correction coefficient to the NO gas on the basis of the detection correction value calculated for the NO gas, so that the H2S gas and the VOCs gas affect the NO gas, Lt; / RTI > Here, the first gas primary correction coefficient is set based on the detection correction value calculated for the H2S gas and the detection correction value calculated for the VOCs gas.

In the first correction step S31, the second gas first correction coefficient applied to the H2S gas by the NO gas and the VOCs gas at the detection correction value calculated for the H2S gas is applied to the second gas 1 And calculates a difference correction value. Here, the second gas primary correction coefficient is set based on the detection correction value calculated for the NO gas and the detection correction value calculated for the VOCs gas.

The first correction step (S31) may further include applying a third gas first correction coefficient to the VOCs gas, wherein the NO gas and the H2S gas affect the VOCs gas at the detection correction value calculated for the VOCs gas, And calculates a difference correction value. Here, the third gas primary correction coefficient is set based on the detection correction value calculated for the NO gas and the detection correction value calculated for the H2S gas.

Then, the first correction value for the biogas is as follows.

Vno (1) = Vno (0) - Vno (h2s (0)) - Vno (voc

Vh2s (1) = Vh2s (0) - Vh2s (no (0)) - Vh2s (voc (0)

Vvoc (1) = Vvoc (0) - Vvoc (no (0)) - Vvoc (h2s (0)

Here, Vno (1) is the first gas primary correction value, Vh2s (1) is the second gas primary correction value, and Vvoc (1) is the third gas primary correction value.

Also, Vno (h2s (0)) is included in the first gas primary correction coefficient due to the influence of the H2S gas on the first sensor 21. [ Vno (h2s (0)) may be preset to 9% to 11% of Vh2s (0). In one embodiment of the invention, Vno (h2s (0)) is preset to 10% of Vh2s (0).

Further, Vno (voc (0)) is included in the first gas primary correction coefficient due to the influence of the VOCs gas on the first sensor 21. [ Vno (voc (0)) may be preset to 9% to 11% of Vvoc (0). In one embodiment of the invention, Vno (voc (0)) may be set to 10% of Vvoc (0).

Further, Vh2s (no (0)) is included in the second gas primary correction coefficient due to the influence of the NO gas on the second sensor 22. [ Vh2s (no (0)) can be preset to 9% to 11% of Vno (0). In one embodiment of the present invention, Vh2s (no (0)) may be preset to 10% of Vno (0).

Further, Vh2s (voc (0)) is included in the second gas primary correction coefficient due to the effect of the VOCs gas on the second sensor 22. [ Vh2s (voc (0)) can be preset to 9% to 11% of Vvoc (0). In one embodiment of the invention, Vh2s (voc (1)) may be preset to 10% of Vvoc (0).

Further, Vvoc (no (0)) is included in the third gas primary correction coefficient due to the influence of the NO gas on the third sensor 23. Vvoc (no (0)) may be preset to 9% to 11% of Vno (0). In one embodiment of the present invention, Vvoc (no (0)) may be preset to 10% of Vno (0).

Also, Vvoc (h2s (0)) is included in the third gas correction coefficient due to the influence of the H2S gas on the third sensor 23. [ Vvoc (h2s (0)) may be preset to 9% to 11% of Vh2s (0). In one embodiment of the invention, Vvoc (h2s (0)) may be preset to 10% of Vh2s (0).

The primary correction values for the corresponding biosensor calculated through the first correction step S31 are stored in a data storage unit 56 described later.

In the second correction step (S32), a secondary correction value is calculated by applying a secondary correction coefficient on the biogas other biogas other than the biogas to the detection correction value calculated for the biogas.

In more detail, in the second correction step (S32), the first gas secondary correction coefficient that the H2S gas and the VOCs gas exert on the NO gas at the detection correction value calculated for the NO gas is applied to the first gas The secondary correction value is calculated. Here, the first gas secondary correction coefficient is set based on the second gas primary correction value calculated for the H2S gas and the third gas primary correction value calculated for the VOCs gas.

The second correction step (S32) may further include applying a second gas secondary correction coefficient to the H2S gas, wherein the NO gas and the VOCs gas affect the H2S gas at the detection correction value calculated for the H2S gas, And calculates a difference correction value. Here, the second gas secondary correction coefficient is set based on the first gas primary correction value calculated for the NO gas and the third gas primary correction value calculated for the VOCs gas.

Further, in the second correction step (S32), the NO gas and the H2S gas apply the third gas secondary correction coefficient to the VOCs gas at the detection correction value calculated for the VOCs gas to obtain the third gas 2 And calculates a difference correction value. Here, the third gas secondary correction coefficient is set based on the first gas primary correction value calculated for the NO gas and the second gas primary correction value calculated for the H2S gas.

Then, the secondary correction value for the biogas is as follows.

Vno (2) = Vno (0) - Vno (h2s (1)) - Vno (voc

Vh2s (2) = Vh2s (0) - Vh2s (no (1)) - Vh2s (voc (1)

Vvoc (2) = Vvoc (0) - Vvoc (no (1)) - Vvoc (h2s (1)

Here, Vno (2) is the first gas secondary correction value, Vh2s (2) is the second gas secondary correction value, and Vvoc (2) is the third gas secondary correction value.

Further, Vno (h2s (1)) is included in the first gas secondary correction coefficient due to the influence of the H2S gas on the first sensor 21. [ Vno (h2s (1)) may be set to 9% to 11% of Vh2s (1). In one embodiment of the invention, Vno (h2s (1)) is preset to 10% of Vh2s (1).

Further, Vno (voc (1)) is included in the first gas secondary correction coefficient due to the influence of the VOCs gas on the first sensor 21. [ Vno (voc (1)) may be preset to 9% to 11% of Vvoc (1). In one embodiment of the present invention, Vno (voc (1)) may be preset to 10% of Vvoc (1).

Further, Vh2s (no (1)) is included in the second gas secondary correction coefficient due to the influence of the NO gas on the second sensor 22. Vh2s (no (1)) can be preset to 9% to 11% of Vno (1). In one embodiment of the present invention, Vh2s (no (1)) may be preset to 10% of Vno (1).

Further, Vh2s (voc (1)) is included in the second gas secondary correction coefficient due to the influence of the VOCs gas on the second sensor 22. [ Vh2s (voc (1)) can be preset to 9% to 11% of Vvoc (1). In one embodiment of the present invention, Vh2s (voc (1)) may be preset to 10% of Vvoc (1).

Further, Vvoc (no (1)) is included in the third gas secondary correction coefficient due to the influence of the NO gas on the third sensor 23. [ Vvoc (no (1)) may be preset to 9% to 11% of Vno (1). In one embodiment of the present invention, Vvoc (no (1)) may be preset to 10% of Vno (1).

Further, Vvoc (h2s (1)) is included in the third gas secondary correction coefficient due to the influence of the H2S gas on the third sensor 23. [ Vvoc (h2s (1)) may be preset to 9% to 11% of Vh2s (1). In one embodiment of the present invention, Vvoc (h2s (1)) may be preset to 10% of Vh2s (1).

The secondary correction values for the corresponding biosensor calculated through the second correction step S32 are stored in a data storage unit 56 described later.

The correction value comparison step includes a first correction value comparison step (S33).

The first correction value comparison step S33 compares the error between the secondary correction value for the corresponding biogas and the primary correction value for the corresponding biogas with a predetermined error range.

In more detail, the first correction value comparison step (S33) compares the first gas error between the first gas secondary correction value and the first gas primary correction value with a predetermined first gas error range.

In addition, the first correction value comparison step (S33) compares the second gas error between the second gas correction value and the second gas correction value with a predetermined second gas error range.

The first correction value comparison step S33 compares the third gas error between the third gas correction value and the third gas correction value with a predetermined third gas error.

After the first correction value comparison step S33, the errors and predetermined error ranges are stored in a data storage unit 56 described later.

The concentration calculation step (S4) calculates the concentration of the biogas using the gas correction value. If the error between the secondary correction value for the biogas and the primary correction value for the biogas is included in the predetermined error range, the concentration calculation step S4 calculates the secondary correction value for the biogas The concentration of the biogas can be calculated.

More specifically, the concentration calculating step (S4) calculates the concentration of the NO gas by using the first gas secondary correction value when the first gas error is included in the predetermined first gas error range.

The concentration calculation step S4 calculates the concentration of the H2S gas using the second gas secondary correction value when the second gas error is included in the predetermined second gas error range.

The concentration calculation step S4 calculates the concentration of the VOCs gas using the third gas secondary correction value when the third gas error is included in the predetermined third gas error range.

Then, the concentration for the biogas can be calculated by a predetermined relation based on the secondary correction value of the biogas, the minimum value of the value detected by the biosensor, and the signal slope of the biosensor.

The concentration of the biogas calculated through the concentration calculation step S4 is stored in a data storage unit 56 described later.

The concentration comparison step (S5) compares the concentration with a preset reference concentration corresponding to the biogas. Here, the preset reference concentration is the concentration of the biogas in which the medical opinion is reflected for the biogas.

More specifically, the concentration comparison step (S5) compares the first concentration calculated corresponding to the NO gas with a predetermined first reference concentration.

The concentration comparison step S5 compares the second concentration calculated corresponding to the H2S gas with a predetermined second reference concentration.

The concentration comparison step S5 compares the third concentration calculated corresponding to the VOCs gas with a predetermined third reference concentration.

After the concentration comparison step S5, the concentrations and predetermined reference concentrations are stored in a data storage unit 56 described later.

In this case, when the concentration is not included in the predetermined reference concentration corresponding to the biogas through the concentration comparison step (S5), the medical indication indicates "border disease" or "danger disease" (S6) to inform the user of the abnormal findings corresponding to the medical findings. Although not shown, the disease notification step S6 may be expressed by means of a screen, an alarm, or the like, so that the user can recognize the information through visual, auditory, tactile, or the like.

In more detail, when the concentration of the NO gas is not included in the predetermined first reference concentration, diseases such as asthma, acute respiratory disease, pneumonia, lung cancer, etc. due to medical findings are a concern, Or notifies the user of the risk factor of the NO gas corresponding to the concentration of the NO gas.

If the concentration of the H2S gas is not included in the predetermined second reference concentration, a disease such as a respiratory inflammatory disease may be medically diagnosed. Therefore, the disease notification step (S6) Informs the user or informs the user of the risk factor of the H2S gas corresponding to the concentration of the H2S gas.

When the concentration of the VOCs gas is not included in the predetermined third reference concentration, diseases such as lung cancer and diabetes mellitus are feared due to medical findings. Therefore, the disease notification step (S6) Informs the user or informs the user of the risk factors of the VOCs gas corresponding to the concentration of the VOCs gas.

Finally, when the concentration is included in the preset reference concentration corresponding to the biogas through the concentration comparison step S5, it indicates that there is no abnormality in the disease due to the medical findings. Therefore, in the normal step S7 ) To inform the user of the normal findings corresponding to the medical findings. Although not shown, the normal step S7 may be expressed by means of a screen, an alarm, or the like so that the user can perceive it through visual, auditory, tactile, or the like.

In the method of analyzing single breathing gas according to an embodiment of the present invention, the second detection value correction step (S3) further includes a third correction step (S34), and the correction value comparison step includes a second correction value comparison step (S35).

The third correction step S34 is performed when the error of the biogas deviates from the predetermined error range through the first correction value comparison step S33. In the third correction step S34, a j-th correction coefficient (j is a constant increasing from 3) applied to the biogas other than the biogas is applied from the detection correction value calculated for the biogas Thereby calculating the j-th correction value.

In more detail, the third correction step (S34) may be performed when the first gas error deviates from the predetermined first gas error range through the first correction value comparison step (S33) The first gas j-order correction value is calculated by applying a first gas j-order correction coefficient to the NO gas on the basis of the H2S gas and the VOCs gas.

The first gas j-order correction coefficient is set based on the second gas j-1 correction value calculated for the H2S gas and the third gas j-1 correction value calculated for the VOCs gas do. The first gas j-th correction coefficient may be set to 9% to 11% of the second gas j-1 correction value calculated for the H2S gas. In one embodiment of the present invention, the first gas j-order correction coefficient may be preset to 10% of the second gas j-1 correction value calculated for the H2S gas. The first gas j-th correction coefficient may be set to 9% to 11% of the third gas j-1 correction value calculated for the VOCs gas. In one embodiment of the present invention, the first gas j-order correction coefficient may be preset to 10% of the third gas j-1 correction value calculated for the VOCs gas.

The third correction step (S34) may further include the step of, when the second gas error is out of the predetermined second gas error range through the first correction value comparison step (S33), correcting the detection correction A second gas j-order correction value is calculated by applying a second gas j-order correction coefficient to the H2S gas, wherein the NO gas and the VOCs gas affect the H2S gas.

The second gas j-order correction coefficient is set based on the first gas j-1 correction value calculated for the NO gas and the third gas j-1 correction value calculated for the VOCs gas do. The second gas j-order correction coefficient may be preset to 9% to 11% of the first gas j-1 correction value calculated for the NO gas. In one embodiment of the present invention, the second gas j-order correction coefficient may be preset to 10% of the first gas j-1 correction value calculated for the NO gas. The second gas j-th correction coefficient may be set to 9% to 11% of the third gas j-1 correction value calculated for the VOCs gas. In one embodiment of the present invention, the first gas j-order correction coefficient may be preset to 10% of the third gas j-1 correction value calculated for the VOCs gas.

The third correction step (S34) may further include a third correction value comparison step (S33), wherein when the third gas error deviates from a predetermined third gas error range, the detection correction The third gas j-th correction value is calculated by applying a third gas j-th correction coefficient to the NO gas and the H2S gas on the VOCs gas.

The third gas j-order correction coefficient is set based on the first gas j-1 correction value calculated for the NO gas and the second gas j-1 correction value calculated for the H2S gas do. The third gas j-th correction coefficient may be preset to 9% to 11% of the first gas j-1 correction value calculated for the NO gas. In one embodiment of the present invention, the third gas j-th correction coefficient may be preset to 10% of the first gas j-1 correction value calculated for the NO gas. The third gas j-th correction coefficient may be set to 9% to 11% of the second gas j-1 correction value calculated for the H2S gas. In one embodiment of the present invention, the third gas j-th correction coefficient may be preset to 10% of the second gas j-1 correction value calculated for the H2S gas.

Then, the secondary correction value for the biogas is as follows.

Vno (j) = Vno (0) - Vno (h2s (j-1)) - Vno (voc

Vh2s (j) = Vh2s (0) - Vh2s (no (j-1)) - Vh2s (voc (1)

Vvoc (j) = Vvoc (0) - Vvoc (no (j-1)) - Vvoc (h2s

Here, Vno (j) is the first gas j-th correction value, Vh2s (j) is the second gas j-th correction value, and Vvoc (j) is the third gas j-th correction value.

Further, Vno (h2s (j-1)) is included in the first gas j-th correction coefficient due to the influence of the H2S gas on the first sensor 21. [ Vno (h2s (j-1)) may be preset to 9% to 11% of Vh2s (j-1). In one embodiment of the present invention, Vno (h2s (j-1)) is preset to 10% of Vh2s (j-1).

Further, Vno (voc (j-1)) is included in the first gas j-th correction coefficient due to the influence of the VOCs gas on the first sensor 21. [ Vno (voc (j-1)) may be preset to 9% to 11% of Vvoc (j-1). In one embodiment of the present invention, Vno (voc (j-1)) may be preset to 10% of Vvoc (j-1).

Further, Vh2s (no (j-1)) is included in the second gas j-th correction coefficient due to the influence of the NO gas on the second sensor 22. [ Vh2s (no (j-1)) may be preset to 9% to 11% of Vno (j-1). In an embodiment of the present invention, Vh2s (no (j-1)) may be preset to 10% of Vno (j-1).

Also, Vh2s (voc (j-1)) is included in the second gas j-th correction coefficient due to the influence of the VOCs gas on the second sensor 22. [ Vh2s (voc (j-1)) may be preset to 9% to 11% of Vvoc (j-1). In one embodiment of the present invention, Vh2s (voc (j-1)) may be preset to 10% of Vvoc (j-1).

Further, Vvoc (no (j-1)) is included in the third gas j-th correction coefficient due to the influence of the NO gas on the third sensor 23. [ Vvoc (no (j-1)) may be preset to 9% to 11% of Vno (j-1). In an embodiment of the present invention, Vvoc (no (j-1)) may be preset to 10% of Vno (j-1).

Also, Vvoc (h2s (j-1)) is included in the third gas j-th correction coefficient due to the influence of the H2S gas on the third sensor 23. [ Vvoc (h2s (j-1)) may be preset to 9% to 11% of Vh2s (j-1). In one embodiment of the present invention, Vvoc (h2s (j-1)) may be preset to 10% of Vh2s (j-1).

The j-th correction values for the corresponding biosensor calculated through the third correction step S34 are stored in a data storage unit 56 described later.

The second correction value comparison step S35 compares the error between the j-th correction value for the corresponding biogas and the j-1th correction value for the corresponding biogas with a predetermined error range.

More specifically, the second correction value comparison step (S35) compares the first gas error between the first gas j-order correction value and the first gas j-first correction value with a predetermined first gas error range .

The first correction value comparison step S33 compares a second gas error between the second gas j-order correction value and the second gas j-first correction value with a predetermined second gas error range.

Also, the first correction value comparison step S33 compares the third gas error between the third gas j-order correction value and the third gas j-first correction value with a predetermined third gas error.

The errors and predetermined error ranges that have undergone the second correction value comparison step S35 are stored in a data storage unit 56 described later.

Accordingly, when the error between the j-th correction value for the biogas and the j-1th correction value for the biogas is included in the predetermined error range, the concentration calculating step S4 calculates the concentration of the biogas the concentration of the biogas can be calculated using the j-th correction value.

If the error exceeds the predetermined error range through the second correction value comparison step S35, j may be increased by one and then the third correction step S34 may be performed.

Therefore, until the detection correction value calculated for the biogas converges to a specific value, the biosensor can accurately detect the corresponding biogas and improve the accuracy of calculation of the concentration for the biogas .

The method of analyzing single breathing gas according to an embodiment of the present invention may further include an initialization step (S1-1). In the initialization step S1-1, the biosensor 20, the pressure sensor 30, and the humidity sensor 40 are operated so that the biosensor 20, the pressure sensor 30, and the humidity sensor 40 are operated in the absence of the respiratory organ before the respiratory organ passes through the transfer tube. And initializes the detection values of the sensor 20, the pressure sensor 30, and the humidity sensor 40. The initialization step S1-1 may be performed before the detection step S1.

The method for analyzing single breathing gas according to an embodiment of the present invention may further include a zeroing step (S1-2). The zeroing step S1-2 sets the detection values of the biosensor 20, the pressure sensor 30 and the humidity sensor 40 to "0 ". The zeroing step S1-2 may be performed before the detecting step S1. Also, the zeroing step S1-2 may be performed after the initializing step S1-1.

The method of analyzing single breathing gas according to an embodiment of the present invention may further include breathing gas transfer step (S1-3).

The respiratory gas transfer step S1-3 blows the respiratory gas into the suction port 111 through the single breath of the user so that the respiratory body passes through the transfer tube 11 and is discharged to the discharge port 112. [ The respiratory gas transfer step (S1-3) may be carried out by the user inhaling the respiratory gas by putting it in the suction port (111). The respiratory gas transfer step (S1-3) is performed after the initialization step (S1-1) and the zeroing step (S1-2), thereby improving the detection accuracy.

In the method for analyzing single breathing gas according to an embodiment of the present invention, the peak velocity of respiratory gas generated through single breathing using the pressure sensor 30, the humidity sensor 40, and three biosensors, It has been described that the humidity of the gas and the three biogas (NO gas, H2S gas, and VOCs gas) contained in the respiratory gas are detected and the concentrations of the three biogas are detected based on the detected biogas. However, The method of analyzing single breathing gas according to another embodiment of the present invention detects two biogas using a pressure sensor 30, a humidity sensor 40 and two biosensors, and based on this, It is possible to detect the concentration of the biogas.

The method for analyzing a single breathing gas according to another embodiment of the present invention includes a detecting step S1, a first detecting value correcting step S2, a second detecting value correcting step S3, a concentration calculating step S4, , And may further include a concentration comparison step (S5). Here, the biogas includes a first biogas and a second biogas, the biosensor 20 includes a first biosensor for detecting the first biogas, a second biosensor for detecting the second biogas, A biosensor may be included.

In another embodiment of the present invention, the first biogas is NO gas, the second biogas is H2S gas, the first biosensor is the first sensor 21, the second biosensor is a second Sensor 22 will be described.

The detecting step S1 is a step of obtaining the peak velocity of respiratory gas generated through the single breath, detecting the humidity of the respiratory gas as in the embodiment of the present invention, and using the biosensor 20, The biogas contained in the respiratory gas can be detected according to the disease of the subject.

In addition, the first detection value correction step (S2) removes the influence of the peak speed and the humidity on the biosensor from the detection value detected by the corresponding biosensor to obtain a detection correction value.

The detection correction value for the biosensor will now be described.

Vno (0) = Vno (B) - Vno (H, F)

Vh2s (0) = Vh2s (B) - Vh2s (H, F)

The second detection value correction step S3 may include a first correction step S31, a second correction step S32 and a first correction value comparison step S33.

More detail. The first correction step (S31) may include applying a first gas first correction coefficient to the first biogas on the basis of the detection correction value calculated for the first biogas, And calculates a difference correction value.

Here, the first gas primary correction coefficient is set based on the detection correction value calculated for the second biogas. The first gas primary correction coefficient may be preset to 9% to 11% of the detection correction value calculated for the second biogas. In another embodiment of the present invention, the first gas primary correction coefficient may be preset to 10% of the detection correction value calculated for the second biogas.

The first correction step S31 may further include applying a second gas first correction coefficient to the second biogas on the basis of the detection correction value calculated for the second biogas, And the gas primary correction value is calculated.

Here, the second gas primary correction coefficient is set based on the detection correction value calculated for the first biogas. The second gas primary correction coefficient may be preset to 9% to 11% of the detection correction value calculated for the first biogas. In another embodiment of the present invention, the second gas primary correction coefficient may be preset to 10% of the detection correction value calculated for the first biogas.

Then, the first correction value for the biogas is as follows.

Vno (1) = Vno (0) - Vno (h2s (0))

Vh2s (1) = Vh2s (0) - Vh2s (no (0))

In more detail, in the second correction step (S32), the first biasing correction coefficient applied to the first biogas by the second biogas from the detection correction value calculated for the first biogas is applied 1 gas secondary correction value.

Here, the first gas secondary correction coefficient is set based on the second gas primary correction value calculated for the second biogas. The first gas secondary correction coefficient may be set to 9% to 11% of the second gas primary correction value calculated for the second biogas. In another embodiment of the present invention, the first gas secondary correction coefficient may be preset to 10% of the second gas primary correction value calculated for the second biogas.

The second correction step S32 may further include applying a second gas secondary correction coefficient to the second biogas on the basis of the detection correction value calculated for the second biogas, And the gas secondary correction value is calculated. Here, the second gas secondary correction coefficient is set based on the first gas primary correction value calculated for the first biogas. The second gas secondary correction coefficient may be set to 9% to 11% of the first gas primary correction value calculated for the first biogas. In another embodiment of the present invention, the second gas secondary correction coefficient may be preset to 10% of the first gas primary correction value calculated for the first biogas.

The errors and predetermined error ranges that have undergone the first correction value comparison step S33 are stored in a data storage unit 56 described later.

More specifically, the concentration calculating step S4 calculates the concentration of the first biogas using the first gas secondary correction value when the first gas error is included in the predetermined first gas error range .

The concentration calculating step S4 calculates the concentration of the second biogas using the second gas secondary correction value when the second gas error is included in the predetermined second gas error range.

More specifically, the concentration comparison step (S5) compares the first concentration calculated corresponding to the first biogas with a predetermined first reference concentration.

Also, the concentration comparing step (S5) compares the second concentration calculated corresponding to the second biogas with a predetermined second reference concentration.

The concentrations and predetermined reference concentrations that have undergone the concentration comparison step S5 are stored in a data storage unit 56 described later.

The steps according to the result of the density comparison step S5 are the same as those in the embodiment of the present invention, and a description thereof will be omitted.

In another embodiment of the present invention, the second detection value correction step (S3) may further include a third correction step (S34) and a second correction value comparison step (S35).

More specifically, the third correction step (S34) may further include the step of comparing the first correction value (S33) with the correction value calculated for the first biogas when the first gas error deviates from a predetermined first gas error range And a first gas j-th correction coefficient (j is a constant increasing from 3) applied to the first biosensor from the second biogas at the detection correction value is calculated.

Here, the first gas j-order correction coefficient is set based on the second gas j-1 correction value calculated for the second biogas. The first gas j-order correction coefficient may be set to 9% to 11% of the second gas j-1 correction value calculated for the second biogas. In another embodiment of the present invention, the first gas j-order correction coefficient may be preset to 10% of the second gas j-1 correction value calculated for the second biogas.

In addition, the third correction step (S34) may further include, when the second gas error deviates from a predetermined second gas error range through the first correction value comparison step (S33) A second gas j-th correction value is calculated by applying a second gas j-th correction coefficient that the first biogas applies to the second biosensor in the detection correction value.

Here, the second gas j-order correction coefficient is set based on the first gas j-1 correction value calculated for the first biogas. The second gas j-th correction coefficient may be set to 9% to 11% of the first gas j-1 correction value calculated for the first biogas. In another embodiment of the present invention, the second gas j-th correction coefficient may be preset to 10% of the first gas j-1 correction value calculated for the first biogas.

Then, the secondary correction value for the biogas is as follows.

Vno (j) = Vno (0) - Vno (h2s (j-1))

Vh2s (j) = Vh2s (0) - Vh2s (no (j-1))

Also, the second correction value comparison step S35 compares the second gas error between the second gas j-order correction value and the second gas j-1 correction value with a predetermined second gas error range.

The method for analyzing single breathing gas according to another embodiment of the present invention detects four or more biogas corresponding thereto using four or more biosensors and detects concentrations of four or more biogas based on the detected four or more biogas can do.

In another embodiment, the method for analyzing single breathing gas according to another embodiment of the present invention is characterized in that the biogas includes n biogas (n is a constant equal to or greater than 2) It can be generalized to include the same n biosensors corresponding to the biogas.

In the method for analyzing single breathing gas according to another embodiment of the present invention, the same or simpler explanation as the one embodiment of the present invention or the other embodiment of the present invention will be omitted.

In the second detection value correcting step S3, an i-th correction coefficient (i = 1, 2, 3, 4, A first correction step (S31) of calculating an i-th correction value by applying a correction value to the detected correction value for each of the n biogas, A second correction step (S32) of calculating an i + 1 st order correction value by applying an i + 1 st order correction coefficient to the biosensor, a second correction step (S32) of calculating i + And a correction value comparing step of comparing an error between the i-th correction value and a predetermined error range.

Here, the primary correction coefficient is set based on the detection correction value calculated for biogas other than the biogas among the n biogas, and the i + 1 < th > The correction value may be set based on the i-th correction value calculated for the biogas other than the gas.

If the error exceeds the predetermined error range through the correction value comparison step, i may be increased by one and then the second correction step S32 may be performed.

Hereinafter, an apparatus for analyzing a single breathing gas according to an embodiment of the present invention will be described.

FIG. 5 is a view showing an apparatus for analyzing a single breathing apparatus according to an embodiment of the present invention, FIG. 6 is a view showing an apparatus for analyzing a single breathing apparatus according to an embodiment of the present invention, 7 is a view showing a control unit in an apparatus for analyzing single breathing gas according to an embodiment of the present invention.

Referring to FIGS. 1 to 4 and 5 to 7, an apparatus for analyzing a single breathing gas according to an embodiment of the present invention can implement a method for analyzing a single breathing gas according to an embodiment of the present invention.

The apparatus for analyzing single breathing gas according to an embodiment of the present invention includes an analysis body 10, a biosensor 20, a pressure sensor 30, a humidity sensor 40, and a control unit 50 do.

The analysis body 10 includes a body body and a linear type transfer pipe 11 through which a respiratory body generated through a single breath is transferred. The body body is provided with an initialization button 70 and a zero button 80, which will be described later. Although not shown, part or all of the control unit 50 may be installed in the body.

The transfer pipe (11) is in the form of a hollow hollow cylinder having both ends open. One side of the transfer pipe 11 is formed with a suction port 111 through which a respiratory body according to a single breath flows and the other side of the transfer pipe 11 is connected to a discharge port 112 through which the respiratory gas introduced into the suction port 111 is discharged ).

The biosensor 20 detects the biogas contained in the respiratory gas according to the disease of the user and is disposed in a direction in which the respiratory organ is transported in the transport pipe 11 according to the type of the biogas to be detected . The biosensor 20 can be divided into a first sensor 21 for detecting NO gas, a second sensor 22 for detecting H2S gas, and a third sensor 23 for detecting VOCs gas.

The pressure sensor 30 is provided on the side of the discharge port 112 through which the respiratory organ is discharged from the transfer pipe 11. The pressure sensor 30 detects the pressure of the respiratory gas to obtain the peak velocity of the respiratory gas.

The humidity sensor 40 is provided at one side of the biosensor 20 or the pressure sensor 30. The humidity sensor (40) detects the humidity of the respiratory gas fed from the feed pipe (11).

The control unit 50 calculates the peak velocity of the respiratory gas on the basis of the pressure of the respiratory gas to be detected and detects the influence of the peak velocity and the humidity on the corresponding biosensor from the detection value detected by the corresponding biosensor And the influence of biogas other than the biogas on the biosensor is removed, and then the concentration of the biogas is calculated.

The control unit (50) includes a peak velocity obtaining unit (55) for obtaining a peak velocity of the respiratory gas on the basis of the pressure detected by the pressure sensor (30) (51) for obtaining a detection correction value by removing the influence of the speed and the humidity on the biosensor, and a second detection value comparing section (51) for comparing the detection correction value calculated for the biogas with a biogas A second detection value estimating unit 52 for removing the influence of the biosensor on the biosensor to obtain the gas correction value and a concentration calculating unit 53 for calculating the concentration of the biogas using the gas correction value .

Acquires the peak velocity in accordance with the operation of the peak velocity acquiring section 55 and performs the first detected value correcting step S2 according to the operation of the first detected value calculating section 51, The second detection value correcting step S3 may be performed according to the operation of the value correcting step S3 and the concentration calculating step S4 may be performed according to the operation of the concentration calculating unit 53 The detailed description will be omitted.

In addition, the control unit 50 may further include a concentration ratio granting unit 54. [

The concentration ratio granting unit 54 compares the concentration with a preset reference concentration corresponding to the biogas. The concentration comparing step (S5) can be performed according to the operation of the concentration ratio granting unit (54).

If the concentration is not included in the preset reference concentration corresponding to the biogas through the concentration comparison step (S5), the user can be informed of the abnormal finding among the medical findings corresponding to the concentration.

In addition, when the concentration is included in the predetermined reference concentration corresponding to the biogas through the concentration comparison step (S5), the user can be informed of the normal findings among the medical findings corresponding to the concentration.

At this time, the medical findings according to the result of the concentration comparison step (S5) can be displayed by means of a screen, an alarm, and the like so that the user can perceive through visual, auditory, tactile, or the like.

The apparatus for analyzing a single breathing gas according to an embodiment of the present invention may further include an exhaust plug 60 coupled to the exhaust port 112. A plurality of discharge holes (61) are formed in the discharge stopper (60).

6, the discharge stopper 60 includes a closed region 60a in which the discharge hole 61 is not provided corresponding to a region where the pressure of the respiratory gas is detected by the pressure sensor 30, And a discharge region 60b in which the discharge hole 61 is formed.

Since the area of the closed region 60a is formed smaller than the area of the discharge region 60b, the respiratory gas is discharged asymmetrically from the discharge stopper 60, thereby amplifying the change effect of the pressure sensor 30 The amplification effect of the detection value detected through the pressure sensor 30 is minimized and the detection error of the detection value detected through the pressure sensor 30 is minimized and the peak velocity of the respiratory gas can be accurately obtained .

In other words, the closed region 60a may be eccentrically formed on one side of the discharge region 60b corresponding to a region where the pressure of the respiratory gas is detected.

The apparatus for analyzing a single breathing gas according to an embodiment of the present invention may be configured such that the biosensor 20, the pressure sensor 30, the humidity sensor 30, And an initialization button 70 for initializing the detection values of the biosensor 20, the pressure sensor 30 and the humidity sensor 40 so that the sensor 40 is operated. The initialization step (S1-1) may be performed according to the operation of the initialization button (70).

The initialization button 70 allows the sensor to be operated to have an initial value, thereby preventing the detection errors of the sensors. Each of the sensors can acquire the surrounding environment information in the default state, and based on the acquired environment information, .

The apparatus for analyzing single breathing gas according to an embodiment of the present invention includes a zero button 80 for setting the detection values of the biosensor 20, the pressure sensor 30, and the humidity sensor 40 to "0 & As shown in FIG. The zeroing step (S1-2) may be performed according to the operation of the zero button (80).

The zero button 80 can set the initial value of each sensor to "0 ", and improve the accuracy of the detection value detected by the sensors based on the obtained difference between the acquired ambient environment information and the set" 0 & .

Here, a reference numeral 521 denotes a first correction value calculating unit for calculating a first correction value from the detection correction value calculated for the biogas by applying a first correction coefficient to the biogas other than the biogas, And the first correction step S31 may be performed according to the operation of the first correction unit 521. [

In addition, a reference numeral 522 denotes a second correction value calculating unit that calculates a second correction value by applying a second correction coefficient to the detected biases calculated for the corresponding biogas on biogas other than the biogas, Government 522. The second correcting step S32 may be performed according to the operation of the second correcting unit 522. [

A reference numeral 523 denotes a first correction value comparing unit 523 for comparing an error between a secondary correction value for the biogas and a primary correction value for the biogas with a predetermined error range. The first correction value comparison step S33 may be performed according to the operation of the first correction value comparison unit 523. [

In addition, a reference numeral 524 denotes a third correction value calculating unit for calculating a correction value for the j-th correction by applying a correction coefficient for the biogas other than the biogas to the biogas based on the detection correction value calculated for the biogas, Government 524. The third correcting step S34 may be performed according to the operation of the third correcting unit 524. [

In addition, reference numeral 525 denotes a second correction value comparing unit 525 for comparing an error between the j-th correction value and the j-1-th correction value for the biogas with a predetermined error range. The second correction value comparison step S35 may be performed according to the operation of the second correction value comparison unit 525. [

In addition, reference numeral 56 denotes a data storage unit 56 in which various values are stored. The values other than the predetermined values stored in the data storage unit 56 may be initialized by the operation of the initialization button 70. [

In addition, the values other than the predetermined values stored in the data storage unit 56 may be set to "0" according to the operation of the zero button 80. [ At this time, the values for i, j, and n necessary for the iteration can maintain the initial values.

Although not shown, in accordance with another embodiment of the present invention, the first correction unit 521 corrects the detection correction value calculated for the corresponding biogas among the n biogas based on the biogas other than the biogas, The second correction unit 522 calculates an i-th correction value by applying an i-th correction coefficient to the gas, and the second correction unit 522 calculates a correction value for the bio- The i + 1-th correction value is calculated by applying an i + 1-th correction coefficient to the biogas, and the correction value comparison unit compares the i + 1-th correction value calculated for one of the n biogas with the i + the error between the i-th correction values is compared with a predetermined error range.

According to the method and apparatus for analyzing single-breathing gas described above, it is possible to accurately analyze the biogas contained in the respiratory gas with a single breath, and to monitor the patient's respiratory disease through the analyzed biogas.

In analyzing or monitoring the respiratory gas, it is possible to make the analyzing apparatus compact without requiring separate pump means or separate water removing means in a mixed gas environment of respiratory gas containing a large amount of water, Can be minimized.

Also, by correcting the detection value of the corresponding biosensor that detects the corresponding biogas by only a single breath through the complex correction algorithm, the peak velocity of the respiratory gas affecting the biosensor 20 in the complex gas environment, the humidity of the respiratory gas , It is possible to eliminate the influence of the biogas other than the biogas on the biosensor and to accurately calculate the concentration of the biogas even in a complex gas environment.

Further, it is also possible to apply a specific correction coefficient to the biosensor on the influence of the biogas other than the biogas on the biosensor, to confirm whether or not the convergence between the correction values to which the correction coefficient is applied is detected by the corresponding biosensor The accuracy of the concentration calculation of the biogas can be improved.

In addition, it is possible to increase the linkage with the target disease in response to the concentration of the biogas, and to predict the disease of the user.

Further, by using the straight type conveying pipe 11 formed of the single inlet 111 and the single outlet 112, it is possible to use the best pump of the respiratory gas for single breath without humidity reduction without using a separate pump means The flow velocity, the volume and the humidity can be accurately detected.

Further, according to the configuration of the discharge stopper 60, the amplification effect of the detection value detected through the pressure sensor 30 is shown, the detection error of the detection value detected through the pressure sensor 30 is minimized, It is possible to accurately obtain the peak velocity of the gas.

In addition, it is possible to prevent the detection error of the sensors through the initialization button 70, to acquire environment information around the analyzer through each of the sensors, and to further reduce errors based on environmental information.

In addition, the initial value of the sensors can be set to "0" through the zero button 80, and the accuracy of the detection value detected by the sensors can be improved on the basis of the zero value.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is to be understood that the invention is not limited to the disclosed embodiments, but, on the contrary, Modify or modify the Software.

S1-1: Initialization step S1-2: Zeroing step S1-3: Breathing gas transporting step
S1: Dimming step S2: First detection value correction step S3: Second detection value correction step
S31: first correction step S32: second correction step S33: first correction value comparison step
S34: Third correction step S35: Second correction value comparison step S4: Concentration calculation step
S5: density comparison step S6: disease notification step S7: normal step
10: analysis body 11: transfer pipe 111: inlet
112: exhaust port 20: biosensor 21: first sensor
22: second sensor 23: third sensor 30: pressure sensor
40: humidity sensor 50: control unit 51: first detection value determining section
52: second detection value control unit 521: first correction unit 522: second correction unit 522:
523: first correction value comparison unit 524: third correction unit 525: second correction value comparison unit
53: Concentration calculation part 54: Concentration ratio delivery part 55: Peak speed acquisition part
56: data storage unit 60: discharge cap 61: discharge hole
60a: Closed area 60b: Discharge area 70: Reset button
80: Zero button

Claims

Detecting a peak velocity of the respiratory gas generated through the single breath and the humidity of the respiratory gas and detecting the biogas contained in the respiratory gas in accordance with the user's disease using the biosensor;
A first detection value correction step of obtaining a detection correction value by subtracting a predetermined value according to the correlation between the peak speed and the humidity and the biosensor from the detection value detected by the corresponding biosensor;
A second detection value correction step of obtaining a gas correction value by applying a correction coefficient to biosensors other than the biogas to the biosensor based on the detection correction value calculated for the biogas; And
And a concentration calculating step of calculating a concentration of the biogas using the gas correction value.

The method according to claim 1,
Wherein the biogas includes a first biogas and a second biogas, the biosensor includes a first biosensor for detecting the first biogas and a second biosensor for detecting the second biogas However,
Wherein the second detection value correction step comprises:
A first gas first correction value applied to the first biosensor by the second biogas at a first detection correction value calculated for the first biogas among the detection correction values, And a second gas correction coefficient applied to the second biosensor by the first biogas at a second detection correction value calculated for the second biogas among the detection correction values, A first correction step of calculating a first correction value;
Calculating a first gas secondary correction value by applying a first gas secondary correction coefficient that the second biogas applies to the first biosensor based on the second gas primary correction value at the first detection correction value A second correction step of correcting the first correction value; And
And a first correction value comparing step of comparing a first gas first error between the first gas secondary correction value and the first gas primary correction value with a predetermined first gas error range,
Wherein the concentration calculating step is performed based on the first gas secondary correction value when the first gas first error is included in the predetermined first gas error range.

3. The method of claim 2,
When the first gas first error exceeds the predetermined first gas error range through the first correction value comparison step,
Wherein the second correction step applies a second gas secondary correction coefficient that the first biogas applies to the second biosensor on the basis of the first gas first correction value at the second detection correction value, A secondary correction value is calculated,
Wherein the second detection value correction step comprises:
A first gas j-th correction coefficient applied to the first biosensor by the second biogas based on the first detection correction value and the second gas j-first correction value (j is a constant increasing from 3) A third correction step of calculating a first gas j-correction value; And
And a second correction value comparison step of comparing the first gas j-1 difference error between the first gas j-order correction value and the first gas j-1 correction value with a predetermined first gas error range ,
And performing the concentration calculating step based on the first gas j-order correction value when the first gas j-1 order error is included in the predetermined first gas error range through the second correction value comparing step Characterized by a single breathing gas analysis method.

The method of claim 3,
When the first gas j-1 order error deviates from the predetermined first gas error range through the second correction value comparison step,
Wherein the third correction step and the second correction value comparison step are repeatedly performed.

5. The method according to any one of claims 1 to 4,
And a concentration comparing step of comparing the concentration with a predetermined reference concentration corresponding to the biogas,
And when the concentration is not included in the preset reference concentration corresponding to the biogas, the user is informed of abnormal findings among the medical findings corresponding to the concentration.

An analytical body having a straight type delivery tube through which a respiratory body generated through a single breath is delivered;
At least two biosensors for detecting the biogas contained in the respiratory gas in accordance with a disease of the user, the biosensors being arranged in a direction in which the respiratory organ is transported in the transport pipe according to the type of the biogas to be detected;
A pressure sensor provided on the side of the discharge pipe through which the respiratory organ is discharged from the transfer pipe and detecting a pressure of the respiratory gas to obtain a peak velocity of the respiratory gas;
A humidity sensor provided at one side of the biosensor or the pressure sensor for detecting the humidity of the respiratory gas; And
And a controller for acquiring a peak velocity of the respiratory gas on the basis of the detected pressure of the respiratory gas and detecting a peak value and a predetermined value according to a correlation between the peak velocity and the humidity and the biosensor from a detection value detected by the corresponding biosensor, And a control unit for applying a correction coefficient to the biosensor other than the biogas to calculate a concentration of the biogas.

The method according to claim 6,
And a discharge cap provided at the discharge port and through which a plurality of discharge holes are formed,
Wherein the discharge stopper includes a closed region in which the discharge hole is not formed corresponding to a region where the pressure of the respiratory gas is detected by the pressure sensor; And
And a discharge region in which the discharge hole is formed.

The method according to claim 6,
Wherein the control unit comprises:
A peak velocity obtaining unit obtaining a peak velocity of the respiratory gas based on the pressure detected by the pressure sensor;
A first detection value determining unit for obtaining a detection correction value by subtracting a predetermined value according to the correlation between the peak speed and the humidity and the biosensor from the detection value detected by the corresponding biosensor;
A second detection value determining unit for obtaining a gas correction value by applying a correction coefficient to biosensors other than the corresponding biogas to the biosensor based on the detection correction value calculated for the biogas; And
And a concentration calculating unit for calculating a concentration of the biogas using the gas correction value.

9. The method of claim 8,
Wherein the control unit comprises:
And a concentration ratio issuing unit for comparing the concentration with a predetermined reference concentration corresponding to the biogas,
And when the concentration is not included in the preset reference concentration corresponding to the biogas, the user is informed of abnormal findings among the medical findings corresponding to the concentration.

The method according to claim 6,
An initialization button for initializing detection values of the biosensor, the pressure sensor, and the humidity sensor such that the biosensor, the pressure sensor, and the humidity sensor are operated without the respiratory organ before the respiratory organ passes through the transfer tube; Further comprising an analyzer for analyzing the single breathing gas.

11. The method of claim 10,
And a zero button for setting the detection values of the biosensor, the pressure sensor, and the humidity sensor to "0" so that the influence of the outside air flowing into the transfer tube is removed after the initialization button is operated A single breathing gas analyzer.