KR101820874B1 - Taraxacum platycarpum sampoo and method for forming taraxacum platycarpum sampoo - Google Patents

Taraxacum platycarpum sampoo and method for forming taraxacum platycarpum sampoo Download PDF

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KR101820874B1
KR101820874B1 KR1020150133206A KR20150133206A KR101820874B1 KR 101820874 B1 KR101820874 B1 KR 101820874B1 KR 1020150133206 A KR1020150133206 A KR 1020150133206A KR 20150133206 A KR20150133206 A KR 20150133206A KR 101820874 B1 KR101820874 B1 KR 101820874B1
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weight
methanol
shampoo
water
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반효정
고경숙
김현희
김미연
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반효정
고경숙
김현희
김미연
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/676Ascorbic acid, i.e. vitamin C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair

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Abstract

A public shampoo and a manufacturing method thereof are disclosed. In the case of porpoise shampoo, the porpoise shampoo may be manufactured with a composition comprising 0.1 to 1 wt% of a hydrothermal extract of perianogenic hydrothermal extract, 0.1 to 1 wt% of a perfluoro methanol extract, 35 to 55 wt% of an anionic surfactant, and an excess of water. Pore-type shampoo is effective for alleviating and improving the dermatitis and scalp damage caused by the oxidizing substance of the permanent or hair dye agent because it contains both antioxidant effect, anti-inflammation, antibacterial and non-toxic effect. In addition, hair dyeing using a hair dyeing agent minimizes hair damage due to the chemical composition of the hair dyeing agent.

Description

FIELD OF THE INVENTION [0001] The present invention relates to a shampoo and a method for producing the same,

TECHNICAL FIELD The present invention relates to a porous shampoo and a method for producing the same, and more particularly, to a porous shampoo containing a porous extract having an antibacterial-anti-inflammatory action, and a method for producing the same.

As the theoretical establishment and the scientific systematicity are introduced in the field of cosmetics and research on various styles is becoming active, the beauty industry is gradually developing. In line with these trends, consumers' preferences and preferences are diversified, and individuality is pursued with a hairstyle. Various techniques such as haircut, permanent, dyeing and decoloring are applied in combination.

In addition, in the way of expressing individual creativity, the beauty of haircuts and permanents is also important, but it is not enough to express individual hair style, so dyeing is often used in order to produce three- . In addition, with the development of the beauty industry, new permanent and dyeing techniques and product launches have increased the number of customers who want to produce a unique hair style. As a result, the number of side effects related to hair damage due to repetitive chemical procedures is rapidly increasing.

In fact, chemical products such as permanent solvents and dyes have been reported to cause adverse effects such as peeling and loss of the eye patch due to their physical and chemical properties, It has been reported that the pH of chemical products and the treatment temperature have a great effect on hair damage. In general, the agent used in permanent waving is a pH between 9.0 and 9.6. As the pH increases, the hair is severely swollen and softened or melted, which can be a great cause of hair damage If the hair dye is applied directly to the scalp, it will cause oxidative stress in the human body If it is left on the scalp, it will stimulate, which may cause not only peeling of the skin but also side effects of the hair loss symptom.

In general, an alkali hair dye is composed of an alkali agent 1 and a hydrogen peroxide 2 agent (H 2 O 2 ). The two ingredients react with each other to color the hair. In this process, . In the case of permanent waving, the cystine bond of the hair is broken by the reducing agent, the oxidizing agent acts, and the cystine bond is again formed. At this time, components such as superoxide (O 2 -), hydrogen peroxide (H 2 O 2 ), and hydroxyl radical (OH), which are not bonded, remain and are called 'active oxygen'.

It is known that active oxygen removes viruses and bacteria that enter the human body, and has a beneficial effect of killing cancer cells. On the other hand, if it is over-produced, it induces various diseases, promotes aging, and adversely affects hair. The hair is composed of about 18 kinds of amino acid aggregate, acidic amino acid, neutral amino acid and basic amino acid. Cystine, a neutral amino acid, is a molecular structure that increases the stability to the physical and chemical properties of the hair. When the hair is damaged, the layer of the skin begins to peel off and dissolve. Thereby, the insecticidal material is released and the hair protein is denatured. Likewise, excessive action of active oxygen oxidizes amino acids, resulting in protein degradation Repeated chemical procedures can make hair damage worse. As a result, antioxidants that inhibit the production of active oxygen have been discovered by US scientists McCord and Fridovich in 1969, a superoxide dismutase (SOD) enzyme, Various studies have been made. Since then, active oxygen and antioxidants have attracted worldwide attention, and in recent years, research has been reported that Vitamin C is a potent antioxidant.

The object of the present invention is to overcome the above-mentioned problems, and it is an object of the present invention to provide a pour point extract which has a function of suppressing active oxygen generated during chemical treatment, anti-inflammation and antibacterial effect, The shampoo of the present invention can be used as a shampoo.

It is another object of the present invention to provide a method for producing a pore-active shampoo which contains the above-mentioned Pokhonyong's extract and has a function of inhibiting antibacterial, anti-inflammatory and active oxygen.

To accomplish the above object, the present invention provides a shampoo according to the present invention having a composition comprising Taraxacum platycarpum Hot water extract, Taraxacum platycarpum Methanol extract, natural nonionic surfactant, .

In one embodiment, the hydrothermal extract of Foongsyang is refluxed at 70 to 90 DEG C to obtain a mixture of distilled water having a pore size of 8 to 13 times the weight of the hydrolyzate, A step of forming an extract from a concentrated solution of a hot-water aqueous solution and a step of lyophilizing the concentrated solution of a hot-water solution of a hot-water solution.

In one embodiment, the perfluoro methanol extract is prepared by stirring a mixture of 8 to 13 times the weight of the perfluorocarbon with methanol and the perchloric acid mixture for 60 to 90 hours to extract the perfluoro methanol extract, Forming an extract from a concentrated solution of methanol in a liquid phase, and lyophilizing the concentrated methanol concentrate.

In one embodiment, the porosity can be used by filtration after pouring out the hot water (70 to 90 ° C) of 8 to 13 times the weight of the porous glass.

In one embodiment, the porous shampoo may comprise at least two functional additives selected from the group consisting of thickening agents, hyaluronic acid, cottonseed oil, L-cystine, ceramide, vitamin E and vitamin C.

The porphyry shampoo may also contain a nonionic surfactant, a cationic surfactant, and an anionic surfactant.

In one embodiment, the porous shampoo comprises 0.1 to 1% by weight of a mineral water extract, 0.1 to 1% by weight of a perfluoro methanol extract, 35 to 55% by weight of an anionic surfactant, 15 to 25% by weight of a cationic surfactant, Weight% and extra porosity.

In order to accomplish the other object, in order to produce a porphyry shampoo according to an embodiment of the present invention, first, a step of preparing Taraxacum platycarpum Hot water extract, Taraxacum platycarpum Methanol extract and a mineral oil ; And 0.1 to 1% by weight of the mineral water extract, 0.1 to 1% by weight of the methanol extract of the pervaporation, 35 to 55% by weight of the anionic surfactant, 15 to 25% by weight of the cationic surfactant, 1.5 to 2.5% by weight of the functional additive, And then mixing them.

The porous shampoo containing the above-mentioned extracts of Pseudomonas aeruginosa contains antioxidative, anti-inflammatory, antibacterial and non-toxic effects, and is effective in alleviating and improving dermatitis and scalp damage caused by oxidizing substances of hair dye. In addition, hair dyeing using a hair dyeing agent minimizes hair damage due to the chemical composition of the hair dyeing agent.

Hereinafter, the porous shampoo and its manufacturing method according to the embodiment of the present invention will be described in detail. While the invention is susceptible to various modifications and alternative forms, specific embodiments thereof are further described in the text. It should be understood, however, that the invention is not intended to be limited to the particular forms disclosed, but includes all modifications, equivalents, and alternatives falling within the spirit and scope of the invention. The terms first, second, etc. may be used to describe various components, but the components should not be limited by the terms. The terms are used only for the purpose of distinguishing one component from another. For example, without departing from the scope of the present invention, the first component may be referred to as a second component, and similarly, the second component may also be referred to as a first component.

The terminology used in this application is used only to describe a specific embodiment and is not intended to limit the invention. The singular expressions include plural expressions unless the context clearly dictates otherwise. In this application, the terms "comprises", "having", and the like are used to specify that a feature, a number, a step, an operation, an element, a part or a combination thereof is described in the specification, But do not preclude the presence or addition of one or more other features, integers, steps, operations, components, parts, or combinations thereof.

On the other hand, unless otherwise defined, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Terms such as those defined in commonly used dictionaries are to be interpreted as having a meaning consistent with the contextual meaning of the related art and are to be interpreted as either ideal or overly formal in the sense of the present application Do not.

Pohang Shampoo

In accordance with one embodiment of the present invention, the porous shampoo has a composition comprising Taraxacum platycarpum Hot water extract, Taraxacum platycarpum Methanol extract, natural nonionic surfactant, and activated water.

In one embodiment, the porpoise shampoo may be prepared with a composition comprising 0.1 to 1 wt% of a hot-water extract of porpoises, 0.1 to 1 wt% of a perfluoro-methanol extract, 35 to 55 wt% of an anionic surfactant, and an excess of propofol.

In another embodiment, the porous shampoo comprises 0.1 to 1% by weight of a mineral water extract, 0.1 to 1% by weight of a perfluoro methanol extract, 35 to 55% by weight of an anionic surfactant, 15 to 25% by weight of a cationic surfactant, 1.5 to 2.5% And extra boiling water may be prepared.

The hydrothermal extraction method of the present invention comprises extracting and concentrating the active ingredient using hot water and containing polyphenols and flavonoids. In particular, the hydrothermal extracts of Pohang and Yeongyang contain more than 35% of polyphenols in comparison with the methanol extract of porpoises.

In order to prepare the hot-water extract of porpoise according to one embodiment, dry-milled porpointer is prepared first. The crushed and dried POCs are washed with water flowing through the dried POCs, and then the primary moisture is removed. The crushed POCs are naturally dried in the shade, pulverized to below 500 μm and stored frozen (below -70 ° C.).

Subsequently, about 8 to 13 times of distilled water, which is about the weight of the dry pulverized phosphorus, is mixed with the phosphoric acid, and the perfluorocarbon mixture is refluxed at a temperature of about 70 to 90 DEG C for about 7 to 10 hours to prepare a pervaporation hot water extract. Next, the hot water extraction solution is cooled at room temperature, filtered through a vacuum filtration apparatus (whatman No. 2), and the filtrate is first concentrated by using a rotary vacuum concentrator to prepare a pervasive hydrothermal concentrate. Next, the pore-active hydrothermal concentrate is frozen at -60 ° C or lower and then secondary-dried using a freeze dryer to obtain a hot-water extraction solution of powdered form. The water exchange rate of the hot-water extract obtained by the above-described method can be calculated by converting the weight of the hot-water extract of the hot-water to the weight of the pre-extraction hot water before the extraction into a percentage (%). The hot-water extract of POCL prepared by the above-mentioned method can be obtained at a yield of about 22 to 26%.

If the content of the mineral water extract of the present invention contained in the shampoo according to the present invention is less than 0.1 to 1 weight, the antioxidative effect of the present invention and the effect of improving the damaged scalp and hair are insignificant. If the content of the hydrothermal extract is greater than 1.0% by weight, the production cost of the hydrothermal extract is significantly increased, which makes it difficult to commercialize the shampoo. Therefore, it is preferable that 0.1 to 1.0% by weight of the hydrothermal extract is used.

The methanol extract of perchlorethylene applied to the porous shampoo includes polyphenols and flavonoids as a result of extracting and concentrating the active ingredient using methanol as a catalyst. Particularly, the methanol extract of perilla plant is characterized in that the polyphenol content is lower than that of the hydrothermal extract of porpoises but the content of the flavonoids is about 20% or more as compared with that of the hydrothermal extract of porpoises.

In order to prepare the methanol extract of the porous methanol according to one embodiment, the dry-milled mineral oil is first prepared. The crushed and dried POCs are washed with water flowing through the dried POCs, and then the primary moisture is removed. The crushed POCs are naturally dried in the shade, pulverized to below 500 μm and stored frozen (below -70 ° C.).

Subsequently, the mixture is mixed with about 8 to 13 times the weight of methanol of the dry pulverized catalyst and methanol. After the mixture is cooled to room temperature and refluxed for about 60 to 90 hours, a methanol solution of the methanol solution is prepared. Subsequently, the methanol extract of POCVD was cooled at room temperature, filtered through a vacuum filtration apparatus (whatman No. 2), and the filtrate was first concentrated using a rotary vacuum concentrator to prepare a concentrated methanol solution. Subsequently, the concentrated methanol solution of perfluoro-methanol is frozen at -60 ° C or lower and then secondary-dried using a freeze dryer to obtain a powdery, perfluoro methanol extract. The rate of conversion of the methanol extract of perovskite obtained by the above-mentioned method can be calculated by converting the weight of the methanol extract of perchlorethylene to the peroxide weight before extraction to the percentage (%). The methanol extract of the mineral oil produced by the above-mentioned method is obtained at a yield of about 18 to 20.5%.

If the content of the methanolic extract of POCL contained in the shampoo according to this embodiment is less than 0.1 weight, the effect of improving the antioxidative, anti-inflammatory, and damaged hair and hair of the present invention is insignificant. If the content of the methanol extract is less than 1.0% by weight, the manufacturing cost of the methanol extract is significantly increased compared to the effect, which makes it difficult to commercialize the shampoo. Therefore, it is preferable that 0.1 to 1.0% by weight of the hydrothermal extract is used.

Particularly, it is an important factor to use the hot air-water extract of Poeongyong and the methanol extract of Poeongyong in combination with the Poe-shampoo of the present invention. These results indicate that the Pohang extract of hot water contains 35% higher polyphenol but less than 20% of flavonoid than methanol extract of Pohang. On the other hand, the methanol extracts of Pohang and Pohang had less than 35% polyphenol content compared with those of Pohang - han hot - water extract, but the flavonoids contained about 20% more than those of Pohang -

 In other words, by using the hot and cold water extracts and the methanol extracts, it is possible to maximize the antioxidant ability, antimicrobial activity and anti-inflammatory properties of the skin disease-causing bacteria by maximizing the polyphenol and flavonoid in the shampoo.

When the content of the anionic surfactant applied to the porous shampoo according to the present embodiment is less than 35% by weight, it is difficult to form sufficient foam as a shampoo and it is difficult to sufficiently clean oil and foreign substances present in the scalp. If the content of the anionic surfactant exceeds 55% by weight, the pH of the shampoo is greatly increased without increasing the cleaning effect of the shampoo.

Therefore, it preferably contains 35 to 55% by weight of the anionic surfactant contained in the porous shampoo according to the present embodiment, more preferably 38 to 52% by weight.

In addition, the cationic surfactant to be applied to the porous shampoo according to the present embodiment is a mild substance that does not irritate the mucous membrane of the nasal mucosa, and it is used in a range of 15 to 25% by weight of a natural surfactant having an anti- do.

As an example, vegetable oils may be used as the functional additive to be applied to the above-mentioned porous shampoo. Examples thereof include grape seed oil, jojoba oil, coconut oil, carrier oil, argan oil and the like. These may be used singly or in a mixture of two or more.

As another example, a thickener, a nonionic surfactant, and the like may be optionally added as a functional additive to be applied to the porous shampoo.

As another example, two or more functional additives may be used as the functional additive to be applied to the porous shampoo if L-cystine, hyaluronic acid, ceramide, vitamin E and vitamin C can be used. Although the above-mentioned additive components refer to the above-mentioned materials, other additives used in the manufacture of cosmetics can be used and are not limited thereto.

In the case of the porous shampoo of the present invention, it is preferable to use the mineral water as the solvent. It is more preferable to use the filtrate obtained by subjecting the porous air to the hot water after filtration with hot water and filtering the hot water at a temperature of 70 to 90 DEG C of 8 to 13 times the weight of the porous water.

Manufacturing method of porpoise shampoo

In order to produce the porphyry shampoo according to one embodiment of the present invention, firstly, Taraxacum platycarpum Hot water extract, Taraxacum platycarpum Methanol extract and Porous water are prepared.

In one embodiment, the hydrothermal extract of Foongsang is obtained by refluxing a mixture of distilled water having a pore size of 8 to 13 times the weight of the filtrate at 70 to 90 ° C to extract the hydrothermal extraction solution of the pore-active hydrothermal solution, A step of forming an extract from a concentrated solution of a hot-water aqueous solution and a step of lyophilizing the concentrated solution of a hot-water solution of a hot-water solution.

In one embodiment, the perfluoro methanol extract may be prepared by mixing a mixture of 8 to 13 times the weight of the perfluorocarbon with methanol for 60 to 90 hours to extract the perfluoro methanol extract, and extracting the perfluoro methanol extract with a rotary- And a lyophilized methanol concentrate solution. The lyophilized methanol concentrate can be prepared by the following steps.

In one embodiment, the pore water can be produced by filtering the pore-forming water with hot water followed by filtration. Specifically, the pore water is poured into warm water (70 to 90 ° C) of 8 to 13 times the pore- .

Thereafter, 0.1 to 1% by weight of the hydrothermal extract of the mineral water, 0.1 to 1% by weight of the methanol extract of the perfluoroalkylether, 35 to 55% by weight of the anionic surfactant, 15 to 25% by weight of the cationic surfactant and the extra- Shampoo can be made.

As another example, the water-in-oil extract may be used in an amount of 0.1 to 1% by weight, 0.1 to 1% by weight of a perfluoro-methanol extract, 1 to 6% by weight of a natural nonionic surfactant, 35 to 55% by weight of an anionic surfactant, %, The functional additive of 1.5 to 2.5% by weight, and the excess of mineral water, to prepare the porous shampoo of the present invention.

Hereinafter, the present invention will be described in more detail with reference to Production Examples, Examples and Evaluation Examples. However, the following Preparation Examples and Examples are for illustrating the present invention, and the present invention is not limited by the following Examples, and various modifications and changes may be made.

Production Example of Porous Hot Water Extract

To prepare the hot - water extract of Poe, hot - water extract was prepared by adding dry distilled water to distilled water of 10 times the weight of the pa - peroxide. The solution was refluxed and cooled at 80 ℃ for 8 hours. After the extraction, the extracted hot water extract was cooled to room temperature, filtered through a vacuum filter (whatman no. 2), and the filtrate was firstly concentrated using a rotary evaporator. Thereafter, the pore-active hydrothermal concentrate was frozen at -70 ° C and then subjected to secondary drying (-70 ° C, 7days) through a freeze dryer to obtain a hot-air extract of pourable.

Examples of preparation of methanol extract of porpoises

To prepare the methanol extract of the crude methanol extract, methanol was added 10 times as much as the pore - of - pore size, and the mixture was stirred at room temperature for 72 hours. The extracted methanol was filtered through a vacuum filter (whatman No. 2), and the filtrate was firstly concentrated using a rotary vacuum concentrator. Subsequently, the methanolic concentrate of perchlorethylene was subjected to secondary drying (-70 ° C, 7days) through a freeze dryer to obtain a methanolic methanol extract.

(1) Determination of polyphenol content of hot and cold water extracts from methanol extract

For each extract (sample), the total polyphenol content per gram was determined by the method of Folin-Denis (Gutfinger T, 1981), the folin-ciacalte rearent being reduced by the polyphenol compound of the extract to produce molybdenum blue Respectively. Add 200 μl of folin-ciacalteu's phenol rearent to 200 μl of each extract (sample), mix and incubate at room temperature for 3 minutes, add 200 μl of 5% Na 2 CO 3 solution, mix for 1 hour at room temperature and use a spectrometer And the absorbance was measured at 750 nm. In order to quantitatively analyze the total phenol content, Tannic acid, a standard substance, was dissolved in DMSO and prepared at a constant concentration. The same amount of test compound was prepared and a calibration curve was prepared. The amount of tannic acid equivalent (TA TA) .

[Table 1]

Figure 112015091797609-pat00001

Table 1 shows the results of total polyphenol content measurement for the hot-water extract of hot-air and the methanol extract of porcupine. It was confirmed that the hydrothermal extract of POE contains 61.98 ± 3.91 TAE㎎ / g of polyphenol and that of the methanol extract of porpoises contains about 34.66 ± 1.66 TAEmg / g of polyphenol. In other words, it was confirmed that the hot water extraction method is a method for effectively extracting polyphenols contained in the pore-active water more efficiently than the methanol extraction method, and it was confirmed that the hot water-extracted water of Poe is containing a high content of polyphenols.

(2) Determination of flavonoid content of hot water extract and methanol extract

Total flavonoid content per gram of extract (sample) was determined by modifying the method of Zia et al. (Zia Z et al, 1999). 2.5 μl of distilled water and 75 μl of 5% NaNO 2 were added to 250 μl of the extract by concentration. After 5 minutes, 10 μl of 10% AlCl 3 · 6H 2 O was added thereto, and the mixture was allowed to stand for 6 minutes and 500 μl of 1N NaOH was added. After 10 minutes, the absorbance of the reaction solution was measured at 415 nm. As a standard substance, Qurcetin was used to prepare each concentration. The same method as in the extract (sample) was used to prepare a calibration curve, and the content was determined using ㎎ QE (quercetin equivalent) as a measurement unit.

[Table 2]

Figure 112015091797609-pat00002

Table 2 shows the total flavonoid content of the hot-water extract of hot-air and methanol extract of porcine-air. It was confirmed that the hydrothermal extract of Panax notoginsia contained flavonoids of 83.93 ± 3.59 QE TAEmg / g and that the methanol extract of porpoises contained about 103.22 ± 3.67 QE ㎎ / g of flavonoids. In other words, it was confirmed that methanol extraction was a more effective method of extracting flavonoids contained in porpoyl than the hot water extraction method, and that the methanol extract of porpoyl contains a high content of flavonoids.

Production Example of Porous Shampoo

The raw materials listed in Table 3 were mixed to prepare a hair-dyeing machine.

[Table 3]

Figure 112015091797609-pat00003

Shampoo treatment method after dyeing

10.0 of the oxidative dyeing agent of A company and 6% of oxidizing agent which are widely used in the beauty industry field were mixed at a ratio of 1: 1.5. After applying to hair, it was allowed to stand at room temperature for 40 minutes, and rinsed once with shampoo. The shampoo rinsed at this time was the same as the general shampoo (N-SP) of Comparative Example 1, the color shampoo (L-SP) of Comparative Example 2, the conditioning shampoo (D-SP) of Comparative Example 3, 1 (T-SP), respectively. The rinsed hair samples were used after natural drying and the pH of the shampoo used in this experiment is shown in Table 4 below.

[Table 4]

Figure 112015091797609-pat00004

Evaluation of thickness of hair

The thickness of the hair washed by each shampoo after dyeing with the oxidative dyeing agent was measured. The results are shown in Table 5 below. At this time, the diameter of the hair was measured at a magnification of 250 by using a scalp diagnostic. 10 samples per group were repeatedly measured 10 times, and the mean value and standard deviation were determined and the significance was verified.

The N-SP hair sample cleaned with the general shampoo of Comparative Example 1 had the thinnest thickness of 24.38 ± 2.14 mm. The amount of L-SP hair shampoo washed with color shampoo was 27.68 ± 2.05 ㎜, the D-SP hair shampoo washed with conditioning shampoo was 28.89 ± 4.06 ㎜, and the T-SP hair shampoo washed with porcine shampoo was 29.91 ± 2.68 ㎜. In other words, the increase in the thickness of the hair when washed with a commercial shampoo is because the antioxidant components of the polyphenols and flavonoids contained in the Pohutukyoryu extract prevent hair damage.

[Table 5]

Figure 112015091797609-pat00005

Evaluation of tensile strength of hair

The tensile strength of hair was measured repeatedly 10 times per sample, and the mean ± standard deviation was obtained. Table 22 shows the tensile strength of each shampoo after rinsing. The tensile strengths were in the order of T-SP> D-SP> L-SP> N-SP. The tensile strength of N-SP washed with ordinary shampoo after dyeing was 81.35 ± 22.54 gf / ㎟, which was 28.65% lower than that of virgin hair. The tensile strength of L-SP washed with color shampoo was 111.00 ± 12.31 The tensile strength of D-SP washed with conditioning shampoo was found to be 112.53 ± 9.96 gf / ㎟, and the two groups belonged to the same group and showed tensile strength similar to that of virgin hair. The tensile strength of T-SP cleaned with a commercial shampoo was 129.07 ± 14.67 gf / ㎟, which was 13.18% higher than virgin hair and 36.97% higher than N-SP. In other words, it can be seen that the antioxidant component of the Pohutukyorye extract inhibits the active oxygen generated in the hair by the oxidative hair dye and reduces the hair damage when using the Pohang shampoo.

[Table 6] Tensile strength measurement of shampoo after dyeing hair

Figure 112015091797609-pat00006

Measurement of the thickness of the skin of the eye using SEM

In order to measure the damage of the eye patch and the thickness of the eye patch, it was observed at 1,000 magnification and 20,000 magnification using a scanning field scanning electron microscope.

The results of observing the surface of the skin using SEM are shown in Table 7 below. After dyeing with oxidative dye, N-SP rinsed with normal shampoo appears to be severely damaged due to some cuticle exfoliation and peeling. The L-SP rinse with color shampoo does not exhibit lifting as compared to N-SP, but some cuticle appears to have evolved. D-SP rinsed with a conditioning shampoo has some cuticle exfoliation observed, but a relatively stable cuticle shape is observed. The T-SP rinse with the shampoo was shampooed in the form of a clean cuticle, similar to untreated hair, and a uniform shape with almost no lifting was found. In other words, it is confirmed that the conditioner shampoo and the pore-type shampoo contain a lot of useful components and the skin becomes healthy.

[Table 7]

*

Figure 112015091797609-pat00007

Evaluation of hair damage using tilene blue

MB staining is a commonly used solution for vital staining. When the cells die, the cell membrane is destroyed and stained. When the cell is alive, the MB The solution is re-extracted to measure the degree of damage. Thus, the more damaged hair absorbs the MB solution, which is the experiment of the principle that the color of extract solution becomes thicker and the absorbance increases when extracting. The degree of damage was measured by converting the hair damage index (HDI) into untreated hair as a control.

The hair damage index (HDI) was measured by MB staining according to washing of each shampoo after dyeing with oxidative dye. The results were as follows: L-SP> N-SP> D-SP> T-SP. Compared to the OD value of virgin hair, the L-SP of the color shampoo was 40.65%, the N-SP of the normal shampoo was 39.95%, while the D-SP of the conditioner shampoo was 16.31% %, And the damage was reduced rapidly. As a result, it was confirmed that the hair loss resulted in loss of the insecticide substance in the hair due to hair dyeing, and the degree of porosity was increased, and the damage could be reduced according to the detergent used immediately after the dyeing. Therefore, in this study, it was confirmed that when hair was cleaned with conditioner shampoo or porpoise shampoo after hair dyeing, hair damage was reduced.

Claims (8)

In a porpoisean shampoo containing a pore-forming ingredient,
A step of extracting the mineral water extract solution by applying 8 to 13 times the weight of the mineral water to the pore-forming water, and a step of concentrating the mineral water extract to prepare a pore-forming hot water concentrate and lyophilizing the hot water concentrate 0.1 to 1% by weight of Taraxacum platycarpum Hot water extract;
Extracting the methanol extract of the pore-forming methanol by applying 8 to 13 times the methanol of the pore-of-water weight, preparing the methanol extract of the pore-forming methanol as a concentrated methanol solution, and lyophilizing the methanolic concentrate of the pore- 0.1 to 1% by weight of Taraxacum platycarpum methanol extract;
35 to 55% by weight of an anionic surfactant;
15 to 25% by weight of a cationic surfactant;
From 1.5 to 2.5% by weight of a functional additive; And
A publicly available shampoo comprising 28.3 to 35.5% by weight of the number of porous spheres formed by fear of hydrothermal activation.
delete delete delete delete 2. The shampoo according to claim 1, wherein the functional additive comprises at least two selected from the group consisting of a thickening agent, hyaluronic acid, cotton seed oil, L-cystine, ceramide, vitamin E and vitamin C. delete Preparing Taraxacum platycarpum Hot water extract, Taraxacum platycarpum Methanol extract, and Porous water, which are formed by hot water, respectively; And
0.1 to 1% by weight of the mineral water extract, 0.1 to 1% by weight of a methanol extract of a perfluoro-anionic surfactant, 35 to 55% by weight of an anionic surfactant, 15 to 25% by weight of a cationic surfactant, 1.5 to 2.5% by weight of a functional additive and 28.3 to 35.5% By weight, based on the total weight of the composition,
Extracting the hot water extraction solution by applying 8 to 13 times the weight of the hydrothermal extract of the hydrothermal activity of the hydrothermal synthesis to the hydrothermal concentrate to obtain a hydrothermal concentrate, , ≪ / RTI >
The above Taraxacum platycarpum methanol extract is prepared by extracting a methanolic extract of methanol from a methanol solution of 8 to 13 times the weight of methanol by using a methanolic extract of methanol to obtain a methanolic concentrate of methanol, Wherein the step of forming the shampoo comprises the steps of:
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KR100771397B1 (en) * 2006-06-08 2007-10-30 인제대학교 산학협력단 Cosmetic composition comprising an extract of dandelion or luteolin isolated therefrom having anti-oxidant activity and anti-inflammatory activity
KR100778662B1 (en) * 2006-06-14 2007-11-29 나드리화장품주식회사 Cleansing composition containing natural oriental plant extracts
JP2010070496A (en) * 2008-09-18 2010-04-02 Tsumura Lifescience Co Ltd Agent for promoting production of hair and/or hair follicle reinforcing factor

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KR100771397B1 (en) * 2006-06-08 2007-10-30 인제대학교 산학협력단 Cosmetic composition comprising an extract of dandelion or luteolin isolated therefrom having anti-oxidant activity and anti-inflammatory activity
KR100778662B1 (en) * 2006-06-14 2007-11-29 나드리화장품주식회사 Cleansing composition containing natural oriental plant extracts
JP2010070496A (en) * 2008-09-18 2010-04-02 Tsumura Lifescience Co Ltd Agent for promoting production of hair and/or hair follicle reinforcing factor

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