KR101723420B1 - Skin boosting apparatus using multiple frequency - Google Patents
Skin boosting apparatus using multiple frequency Download PDFInfo
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- KR101723420B1 KR101723420B1 KR1020150190561A KR20150190561A KR101723420B1 KR 101723420 B1 KR101723420 B1 KR 101723420B1 KR 1020150190561 A KR1020150190561 A KR 1020150190561A KR 20150190561 A KR20150190561 A KR 20150190561A KR 101723420 B1 KR101723420 B1 KR 101723420B1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Electrotherapy Devices (AREA)
Abstract
Description
The present invention relates to an apparatus for absorbing an active ingredient into the skin, and more particularly, to an apparatus and method for absorbing an active ingredient into the skin that absorbs the active ingredient into the skin through two steps using a plurality of pulses .
Human skin tissue consists of stratum corneum, epidermal layer, dermal layer and hypodermis layer. The function of the skin is deteriorated by aging and ultraviolet rays. Representative changes of skin due to aging and ultraviolet rays include wrinkle formation due to reduction and deformation of collagen fibers in the dermis, reduction of skin elasticity due to modification of elastic fibers composed of elastin, activation of tyrosinase present in the epidermal layer And melanin pigmentation. In order to prevent and improve the wrinkle formation, skin elasticity, and pigmentation, studies are being conducted to promote synthesis and collapse of collagen and elastin in the skin, to remove melanin pigment and decrease tyrosinase activity.
In order to maintain and improve the aging and elasticity of the skin, it is possible to cause a biological change by an effect substance. Such methods include a method of applying a substance to the surface of the skin, a method of causing manual diffusion by attaching a mask or a patch and a method of applying a microneedle , Iontophoresis, sonophoresis, electroporation, and the like can be used to cause active diffusion.
A first object of the present invention is to provide an apparatus for absorbing an active ingredient into the skin, which absorbs the active ingredient into the skin through two steps using a plurality of pulses.
A second problem to be solved by the present invention is to provide a method of absorbing an active ingredient into skin that absorbs an active ingredient into the skin through two steps using a plurality of pulses.
In order to achieve the first object of the present invention, there is provided an apparatus for absorbing an active ingredient into skin, comprising: a pulse generator for generating a pulse having a predetermined frequency; And a plurality of electrode units that emit the generated pulses, wherein the pulses generated in the pulse generating unit are applied to the skin applied to the skin or to the skin, which is attached to the skin, In order to move the skin to the surface, the frequency of the next pulse is higher than that of the previous pulse in order of time, and in order to absorb the component moved to the skin surface into the skin, To provide a device characterized by:
According to an embodiment of the present invention, the pulse used to absorb the component into the skin is composed of pulses having three different frequency magnitudes, and is applied to the skin from a pulse having a large frequency, So as to absorb the component into the inside of the skin.
According to an embodiment of the present invention, the first pulse having the highest frequency among the three pulses acts on the horny layer of the skin, the second pulse having the intermediate frequency acts on the skin surface layer, The third pulse acts on the dermal layer to form a cell gap in the lipid bilayer, thereby absorbing the component into the skin.
According to an embodiment of the present invention, the pulse used to move the component to the skin surface is composed of pulses having three different frequency magnitudes, and is applied to the coating or skin deposit from a pulse having a small frequency, And then moving the component to the skin surface by forming an electric wave in the direction of the skin.
According to an embodiment of the present invention, the pulse generator may be configured to multiply the voltage boosted by the boost-up operation to twice the peak value through the H bridge.
According to an embodiment of the present invention, the electrode unit may be formed as two or more pairs so as to have two bipolar contact points.
According to an embodiment of the present invention, the electrode unit may be a semicircular, semi-elliptic, circular, protruding, or brush type.
In order to achieve the second object of the present invention, there is provided a method for absorbing an active ingredient into skin, comprising the steps of: applying a coating applied to the skin using a plurality of pulses having a frequency difference; Moving the component to be absorbed to the skin surface; And a step of absorbing a component moved to the surface of the skin into the skin using a plurality of pulses having a frequency difference, wherein a pulse used to move the component to the skin surface is a pulse, The frequency of which is larger than that of the previous pulse, and the pulse used to absorb the component into the skin is characterized in that the frequency of the next pulse is smaller than that of the previous pulse in the time sequence.
According to the present invention, it is possible to promote absorption of the active ingredient into the skin after moving the active ingredient to the skin surface using a plurality of pulses.
1 is a block diagram of an apparatus for absorbing an active ingredient into skin according to an embodiment of the present invention.
FIG. 2 is an illustration of an application / skin adherence and an inner skin of the skin to which an apparatus for absorbing an active ingredient is applied, according to an embodiment of the present invention.
FIG. 3 is a view showing that an electric perforation is formed in the skin by an apparatus for absorbing an active ingredient on the skin according to an embodiment of the present invention.
4 is a circuit diagram of a pulse generation unit of an apparatus for absorbing an active ingredient into skin according to an embodiment of the present invention.
FIG. 5 shows the shape of an electrode part of an apparatus for absorbing an active ingredient to skin according to an embodiment of the present invention.
6 to 7 show an apparatus for absorbing an active ingredient into skin according to an embodiment of the present invention.
FIG. 8 is a graph showing the difference between the electric stimulation applied and the non-applied electric stimulation by an apparatus for absorbing an effective ingredient in skin according to an embodiment of the present invention.
FIG. 9 is a flow chart of a method of absorbing an active ingredient to skin according to an embodiment of the present invention, and FIG. 10 is a flowchart of a method of absorbing an active ingredient to skin according to another embodiment of the present invention.
Prior to the description of the concrete contents of the present invention, for the sake of understanding, the outline of the solution of the problem to be solved by the present invention or the core of the technical idea is first given.
An apparatus for absorbing an effective component in skin according to an embodiment of the present invention includes a pulse generating unit for generating a pulse having a predetermined frequency and a plurality of electrode units for emitting the generated pulse, The following pulse is frequency-wise higher than the previous pulse in order to move the component to be absorbed into the skin contained in the skin applied to the skin or the skin attachment attached to the skin to the skin surface In order to absorb the component transferred to the skin surface into the skin, the frequency of the next pulse is smaller than that of the previous pulse according to the time sequence.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings. It will be apparent to those skilled in the art, however, that these examples are provided to further illustrate the present invention, and the scope of the present invention is not limited thereto.
BRIEF DESCRIPTION OF THE DRAWINGS The above and other objects, features and advantages of the present invention will become more apparent from the following detailed description of the present invention when taken in conjunction with the accompanying drawings, in which: It is to be noted that components are denoted by the same reference numerals even though they are shown in different drawings, and components of different drawings can be cited when necessary in describing the drawings. In the following detailed description of the principles of operation of the preferred embodiments of the present invention, it is to be understood that the present invention is not limited to the details of the known functions and configurations, and other matters may be unnecessarily obscured, A detailed description thereof will be omitted.
1 is a block diagram of an apparatus for absorbing an active ingredient into skin according to an embodiment of the present invention.
An
The
More specifically, a pulse is used to absorb the active ingredient into the skin. The step of absorbing the active ingredient into the skin using the pulse generated by the
As shown in FIG. 2, applying a pulse to the coating or skin attachment containing the active ingredient to move the active ingredient to the skin surface, and absorbing the active ingredient, which has been transferred to the skin surface, into the skin.
First, a pulse is used to move the ingredients to be absorbed into the skin contained in the skin applied to the skin or adhered to the skin to the skin surface. It is called release-boosting in one step of electrophoresis to move the active ingredient to the skin surface as much as possible.
A pulse is applied to the application or skin attachment to move the ingredients to be absorbed into the skin contained in the skin applied to the skin or the skin attachment attached to the skin to the skin surface. By applying electric pulse stimulation to the application or skin deposit, the medium conductor containing the active ingredient forms a fine electric wave toward the surface of the skin opposite to the current density electrode surface, whereby the active ingredient in the medium conductor It can be moved to the surface of the skin. The active ingredient may be a component intended to be absorbed into the skin, such as cosmetics or drugs. The active ingredient may be included in a cream or celuble type of application that can be applied to the skin, or it may be included in the skin attachment, such as a patch, mask sheet, or hydrogel. Furthermore, it is possible to contact the skin in various ways that can come into contact with the skin.
The pulses used to move the component to the skin surface are generated such that the next pulse is frequency greater than the previous pulse in time order. It is possible to increase the efficiency of moving the effective component by applying a plurality of pulses instead of one pulse.
The pulses used to move the components to the skin surface are composed of pulses having three different frequency magnitudes and are applied to the coating or adherence of the skin starting with a pulse of small frequency to form an electrical impulse in the skin direction, Can be moved to the skin surface. As an example of a pulse, a pulse having three frequencies can be used.
The pulse used to move the component to the skin surface can be preset or adjusted in frequency and time to be externally released. For example, if three pulses with different frequencies are used, the pulse with the lowest frequency has 8 kHz and a pulse can be generated and released for a time of 1 to 100 ms, and the pulse with the middle frequency has a frequency of 16 kHz A pulse can be generated and emitted for a time of 1 to 100 ms and the pulse with the highest frequency has a frequency of 40 kHz and a pulse can be generated and emitted for a time of 1 to 100 ms. Or the lowest frequency pulse may be greater than 0 to 8 kHz, the intermediate pulse may be 8 to 16 kHz, and the highest pulse may be within 16 to 40 kHz. Also, the higher the frequency, the longer the time it takes for the pulse to be emitted. If the movement is performed to some extent, the concentration on the surface of the skin becomes high, and the movement efficiency can be increased by applying the high-frequency pulse for a long time.
After the component is transferred to the skin surface, a pulse is used to absorb the component transferred to the skin surface into the skin. This is called delivery-boosting in two steps of electrical perforation to absorb the active ingredient transferred to the epidermis into the stratum corneum-epidermal layer-dermal layer.
A pulse is applied to the skin to absorb the component transferred to the skin surface into the skin. The pulse used to absorb the component into the skin may be lower in frequency than the previous pulse in the time sequence. The frequency of the pulse applied inversely to the pulse used to move the component to the skin surface becomes smaller. Since the depth of penetration into the skin varies depending on the frequency difference of the pulse, the active ingredient can be sequentially absorbed to the desired skin depth by using the depth. As an example of a pulse, a pulse having three frequencies can be used.
It is composed of pulses having three different frequency magnitudes, and is applied to the skin from a pulse having a large frequency, thereby forming an electric perforation in the skin, so that the component can be absorbed into the skin. When three pulses are used, the first pulse having the highest frequency among the three pulses acts on the horny layer of the skin, the second pulse having the intermediate frequency acts on the skin surface layer, and the third pulse having the lowest frequency Acts on the dermal layer to form a cell gap in the lipid bilayer so that the component can be absorbed into the skin.
The pulse used to absorb the component into the skin can be preset or adjusted in terms of frequency and time to be released to the outside. For example, when three pulses having different frequencies are used, the first pulse having the highest frequency has 8 kHz, and a pulse can be generated and released for 1 to 100 ms. And a pulse can be generated and emitted for a time of 1 to 100 ms, and the pulse having the lowest frequency has a frequency of 2 kHz and a pulse can be generated and emitted for a time of 1 to 100 ms. The frequency of 8 kHz is relatively high and the depth penetrating the skin is very shallow and acts mainly on the horny layer of the skin. The frequency of 4 kHz supplied later is deeper than the depth of 8 kHz, The 2 kHz supplied in the order is relatively lower than 4 kHz and 8 kHz and acts deep into the dermis. As shown in Fig. 3, a first pulse of 8 kHz can apply electric puncturing to the stratum corneum, a second pulse of 4 kHz can apply electric puncturing to the skin layer, and a third pulse of 2 kHz applies electric puncturing to the dermal layer . In the first to third pulses, the first pulse may be 4 to 8 kHz, the second pulse may be 2 to 4 kHz, and the third pulse may be within 0 to 2 kHz. Also, the lower the frequency, the longer the time it takes for the pulse to be emitted. In order to sufficiently absorb the components deep into the skin, it is possible to increase the absorption rate by applying a low-frequency pulse for a long time.
If the depth of the skin to be absorbed is determined, it can be adjusted so that only a pulse having a frequency penetrating to the depth is applied.
The
An embodiment of the specific circuit of the
P1 and P3 are in HIGH state and P4 and P2 are in LOW state to generate a pulse of +15 to 20 V and after that P1 and P3 are in LOW state and P4 and P2 are in HIGH state, And finally a pulse having a peak value of 30 to 40 V is generated.
The
More specifically, the
The
The device for absorbing the active ingredient to the skin according to the embodiment of the present invention can be realized in the form of FIGS. 6 to 7 so that the user can easily grasp, carry, and use the product. FIG. 6 shows a completed embodiment in which power is applied through a battery to form a button for controlling the apparatus, and an electrode 1 and an electrode 2 for applying a pulse are formed. 7 is an internal structural view of the apparatus. The apparatus may include a top mold, a button, a circuit board for generating a pulse, a battery for power supply, a bottom mold, a battery cover, an electrode 1 and an electrode 2. A 1.5 V AAA battery supply can be used to generate a pulse with a peak voltage of 30 to 40 V using a boost up converter.
The results of experiments using an apparatus for absorbing an effective ingredient in skin according to an embodiment of the present invention are shown in FIG. Comparing the case where the electric stimulation is applied and the case where no electric stimulation is applied, it can be seen that there is a large difference in the absorption rate when the electric stimulation is applied.
FIG. 9 is a flowchart of a method of absorbing an active ingredient to skin according to an embodiment of the present invention.
The detailed description of
In
More specifically, the pulses used to move the component to the skin surface are frequency-wise higher in frequency than the previous pulse in the time sequence. The pulses used to move the components to the skin surface are composed of pulses having three different frequency magnitudes and are applied to the coating or adherence of the skin starting with a pulse of small frequency to form an electrical impulse in the skin direction, Can be moved to the skin surface.
In
More specifically, the pulse used for absorbing the component into the skin is frequency-lowered in the order of time, with the next pulse being smaller than the previous pulse. The pulses used to absorb the components into the skin are composed of pulses having three different frequency magnitudes and are applied to the skin from a pulse having a high frequency to form an electric perforation in the skin, The first pulse having the highest frequency of the three pulses acts on the stratum corneum of the skin, the second pulse having the intermediate frequency acts on the skin surface layer, and the third pulse having the lowest frequency has the dermal layer To form a cell gap in the lipid bilayer, so that the component can be absorbed into the skin.
FIG. 10 is a flowchart of a method of absorbing an active ingredient to skin according to another embodiment of the present invention. FIG. 10 is a flowchart illustrating a method of absorbing an active ingredient in skin according to another embodiment of the present invention. kHz -> 16 kHz -> 40 kHz to move the active ingredient to the skin surface. Then, the boosted pulse is output through the H bridge by generating the boost boosting pulse, and the pulse is applied to the skin in the order of 8 kHz -> 4 kHz -> 2 kHz, thereby absorbing the active ingredient into the skin.
As described above, the present invention has been described with reference to particular embodiments, such as specific constituent elements, and limited embodiments and drawings. However, it should be understood that the present invention is not limited to the above- And various modifications and changes may be made thereto by those skilled in the art to which the present invention pertains.
Accordingly, the spirit of the present invention should not be construed as being limited to the embodiments described, and all of the equivalents or equivalents of the claims, as well as the following claims, belong to the scope of the present invention .
100: Apparatus for absorbing active ingredients into skin
110:
120:
Claims (11)
A pulse generator for generating a pulse having a predetermined frequency; And
And a plurality of electrode portions for emitting the generated pulses,
The pulse generated in the pulse generating unit may be,
In order to move the ingredients to be absorbed into the skin contained in the skin applied to the skin or the skin adherence adhered to the skin to the skin surface, the frequency of the next pulse is higher than that of the previous pulse,
In order to absorb the component transferred to the skin surface into the skin, the next pulse has a smaller frequency than the previous pulse,
The pulses used to absorb the components into the skin include,
Wherein the pulse is applied to the skin starting from a pulse having a high frequency to thereby form an electric perforation in the skin to absorb the component into the skin,
The first pulse having the highest frequency among the three pulses acts on the horny layer of the skin, the second pulse having the intermediate frequency acts on the skin surface layer, and the third pulse having the lowest frequency acts on the dermal layer, And forming a cell gap in the bilayer to absorb the component into the skin.
The pulses used to transfer the components to the skin surface are,
Characterized in that it consists of pulses having three different frequency magnitudes and is applied to the application or skin attachment from a small frequency pulse to form an electrical impulse in the direction of the skin thereby moving the component to the skin surface.
Wherein the pulse generator comprises:
Wherein the boosted voltage forms a doubled peak through the H bridge.
The electrode unit includes:
Wherein the first and second electrodes are formed in two or more pairs so as to have two contacts in a bipolar form.
The electrode unit includes:
Semi-elliptical, semi-elliptical, circular, protruding, or brush-shaped.
Moving a component to be absorbed by the skin contained in the coating applied to the skin or adhered to the skin to the skin surface using a plurality of pulses having a frequency difference; And
Absorbing a component moved to the skin surface into a skin using a plurality of pulses having a frequency difference,
The pulses used to move the components to the skin surface are those in which the next pulse is frequency greater than the previous pulse,
The pulse used to absorb the component into the skin is frequency-lowered in the order of time,
The pulses used to absorb the components into the skin include,
Wherein the pulse is applied to the skin starting from a pulse having a high frequency to thereby form an electric perforation in the skin to absorb the component into the skin,
The first pulse having the highest frequency among the three pulses acts on the horny layer of the skin, the second pulse having the intermediate frequency acts on the skin surface layer, and the third pulse having the lowest frequency acts on the dermal layer, Wherein the component is absorbed into the skin by forming a cell gap in the bilayer.
The pulses used to transfer the components to the skin surface are,
Characterized in that it consists of pulses having three different frequency magnitudes and is applied to the application or skin attachment from a small frequency pulse to form an electrical impulse in the direction of the skin thereby moving the component to the skin surface.
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KR1020150190561A KR101723420B1 (en) | 2015-12-31 | 2015-12-31 | Skin boosting apparatus using multiple frequency |
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Cited By (3)
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KR101911789B1 (en) | 2018-01-10 | 2018-10-25 | (주)이지템 | Skin stimulating device for enhancing penetration of effective ingredients |
WO2018207996A1 (en) * | 2017-05-08 | 2018-11-15 | (주)오스힐 | Skin booster including micro-current control means |
KR20190107816A (en) * | 2018-03-13 | 2019-09-23 | (주)더마테크 | Apparatus for Managing Skin, Driving Method of Apparatus for Managing Skin, and Computer Readable Recording Medium |
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KR20040005915A (en) | 2001-04-06 | 2004-01-16 | 마티올리 엔지니어링 엘티디. | Apparatus for skin absorption enhancement |
JP2008212739A (en) * | 1998-09-04 | 2008-09-18 | Woodside Biomedical Inc | Output adjusting method and device in battery driven electrotherapy device |
KR20130037903A (en) * | 2011-10-07 | 2013-04-17 | (주)휴비딕 | Ion injector having a bipolar type probe head |
KR20140001514A (en) * | 2012-06-27 | 2014-01-07 | (주)휴먼드림 | Radio frequency therapeutic apparatus |
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JP2008212739A (en) * | 1998-09-04 | 2008-09-18 | Woodside Biomedical Inc | Output adjusting method and device in battery driven electrotherapy device |
JP2002165889A (en) * | 2000-12-05 | 2002-06-11 | Iijima Seimitsu Kogyo Kk | Skin stimulation device |
KR20040005915A (en) | 2001-04-06 | 2004-01-16 | 마티올리 엔지니어링 엘티디. | Apparatus for skin absorption enhancement |
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2018207996A1 (en) * | 2017-05-08 | 2018-11-15 | (주)오스힐 | Skin booster including micro-current control means |
KR101911789B1 (en) | 2018-01-10 | 2018-10-25 | (주)이지템 | Skin stimulating device for enhancing penetration of effective ingredients |
WO2019139232A1 (en) * | 2018-01-10 | 2019-07-18 | (주)이지템 | Skin stimulating device for enhancing absorption of ingredients effective to skin |
KR20190107816A (en) * | 2018-03-13 | 2019-09-23 | (주)더마테크 | Apparatus for Managing Skin, Driving Method of Apparatus for Managing Skin, and Computer Readable Recording Medium |
KR102120119B1 (en) | 2018-03-13 | 2020-06-08 | (주)더마테크 | Apparatus for Managing Skin and Driving Method of Apparatus for Managing Skin |
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