KR101681646B1 - The dietary fiber extracted from wheat bran for adsorption of polycyclic aromatic hydrocarbons - Google Patents
The dietary fiber extracted from wheat bran for adsorption of polycyclic aromatic hydrocarbons Download PDFInfo
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Abstract
Description
본 발명은 다환 방향족 탄화수소를 흡착하는, 소맥피로부터 추출된 식이섬유에 관한 것이다.The present invention relates to dietary fiber extracted from wheat fatigue, which adsorbs polycyclic aromatic hydrocarbons.
식이섬유는 식품 중에서 채소, 과일 및 해조류 등에 많이 들어 있는 섬유질 또는 셀룰로오스로 알려진 성분으로, 사람의 소화효소로는 소화되지 않고 몸 밖으로 배출되는 고분자 탄수화물이다.Dietary fiber is a high-molecular carbohydrate that is known as fiber or cellulose contained in vegetables, fruits, seaweeds, etc., and is released into the body without being digested by human digestive enzymes.
1970년대 초, 식이섬유를 적게 섭취하는 사람에게 대장암을 비롯해서 심장병 또는 당뇨병 등의 성인병이 많다는 학설이 발표되면서 식이섬유에 대한 관심이 높아졌다. In the early 1970s, interest in dietary fiber was heightened with the announcement that people who consume less dietary fiber are more likely to have adult diseases such as heart disease or diabetes, as well as colon cancer.
사람은 체내에서 에너지를 생성하는 탄수화물, 지방 및 단백질 등 영양소를 섭취해야 살 수 있으나, 식이섬유는 상기 영양소와 그 기능이 다르다. 식이섬유는 대장 내의 세균에 영향을 끼쳐 발암 물질의 작용을 억제하여 대장암을 예방한다. 또한, 콜레스테롤의 흡수를 막아주므로 성인병을 예방하며, 위장의 공복감을 덜 느끼게 하고, 음식물의 흡수를 더디게 하여 콜레스테롤을 걸러낸다. 어떤 식이섬유는 장내에서 식염과 결합하여 몸 밖으로 배출시켜 혈압이 올라가는 것을 막아준다. 따라서, 고혈압의 치료와 예방에 도움이 된다. 비만인 사람은 식이섬유를 충분히 섭취하면 영양분의 소화와 흡수를 억제하면서 만복감을 주기 때문에 과식을 하지 않게 된다. 또한, 대장의 운동을 촉진시켜 변이 내장을 통과하는 시간을 짧게 하고 배변량을 증가시켜 다이어트에도 효과적이다. 그러나 과다하게 섭취하면 물에 녹지 않는 불용성 식이섬유일 경우 무기질의 흡수를 방해하므로 바람직하지는 않다.Humans are able to live by ingesting nutrients such as carbohydrates, fats and proteins that produce energy in the body, but dietary fiber has different functions than the above nutrients. Dietary fiber affects bacteria in the large intestine to inhibit the action of carcinogens and prevent colon cancer. It also prevents cholesterol absorption, preventing adult diseases, lessening hunger hunger, slowing the absorption of food and filtering cholesterol. Some dietary fiber binds to the salt in the intestines and drains it out of the body, preventing blood pressure from rising. Therefore, it helps to treat and prevent hypertension. Obese people eat enough fiber to suppress the digestion and absorption of nutrients while giving fullness, so you will not overeat. In addition, it promotes the movement of the large intestine, shortening the time to pass through the internal organs of the stomach, and increasing the amount of excrement, which is effective for dieting. However, excessive intake of insoluble dietary fiber, which does not dissolve in water, is not desirable because it interferes with the absorption of minerals.
많은 연구 결과를 통하여, 식이섬유들은 각 원재료에 따라 물에 용해되는 성질, 분자량, 구성 성분 등이 매우 상이하여, 상기와 같은 기능을 나타내는 특성과 유효 섭취량 또한 달라지게 된다고 보고되었다.Through many research results, it has been reported that dietary fibers differ in their properties, molecular weight, constituents and the like dissolved in water depending on the respective raw materials, and thus the characteristics and effective intake of the dietary fibers are different.
상기 기능 중 발암 물질을 억제하는 기능이 향후 신약 개발 및 건강 음료 등에 매우 유용할 것으로 보이며, 그에 따라 발암물질을 억제할 수 있는 특성을 갖는 식이섬유의 개발이 필요한 상황이다.
[선행 특허 문헌]
대한민국 특허공개번호 제10-2009-0131495호Among the above functions, the function of inhibiting carcinogens is expected to be very useful for the development of new drugs and health drinks in the future, and development of dietary fiber having characteristics capable of inhibiting carcinogens is required.
[Prior Patent Literature]
Korean Patent Publication No. 10-2009-0131495
본 발명은 발암 물질인 다환 방향족 탄화수소를 흡착하는, 소맥피로부터 추출된 식이섬유를 제공하는 것을 목적으로 한다.It is an object of the present invention to provide dietary fiber extracted from wheat fat, which absorbs polycyclic aromatic hydrocarbons which are carcinogenic substances.
또한, 본 발명은 상기 식이섬유를 포함하는 발암물질 흡착제를 제공하는 것을 목적으로 한다.It is another object of the present invention to provide a carcinogen adsorbent comprising the dietary fiber.
또한, 본 발명은 상기 소맥피로부터 추출된 식이섬유를 이용하여 인체 내 발암물질을 효과적으로 제거하여 발암 위험성을 감소시키는 것을 목적으로 한다.It is another object of the present invention to reduce the risk of carcinogenesis by effectively removing carcinogens in the human body using dietary fiber extracted from the wheat fatigue.
상기 목적을 달성하기 위하여,In order to achieve the above object,
본 발명은 다환 방향족 탄화수소를 흡착하는, 소맥피로부터 추출된 식이섬유를 제공한다.The present invention provides dietary fiber extracted from wheat fat, which adsorbs polycyclic aromatic hydrocarbons.
또한, 본 발명은 상기 소맥피로부터 추출된 식이섬유를 포함하는 다환 방향족 탄화수소 흡착제를 제공한다.The present invention also provides a polycyclic aromatic hydrocarbon adsorbent comprising dietary fiber extracted from the above-mentioned wheat fatigue.
또한, 본 발명은 상기 소맥피로부터 추출된 식이섬유를 이용한 다환 방향족 탄화수소 제거 방법을 제공한다.The present invention also provides a method for removing polycyclic aromatic hydrocarbons from dietary fiber extracted from wheat fat.
또한, 본 발명은 상기 소맥피로부터 추출된 식이섬유를 포함하는 약학 조성물을 제공한다.The present invention also provides a pharmaceutical composition comprising dietary fiber extracted from the above-mentioned wheat fatigue.
또한, 본 발명은 상기 소맥피로부터 추출된 식이섬유를 포함하는 건강식품 조성물을 제공한다.The present invention also provides a health food composition comprising dietary fiber extracted from the wheat fat.
본 발명의 소맥피로부터 추출된 식이섬유는 발암물질 중에서도 다환 방향족 탄화수소를 흡착할 수 있어, 인체 내 발암물질을 효과적으로 제거할 수 있다.The dietary fiber extracted from the wheat fat of the present invention can adsorb polycyclic aromatic hydrocarbons among the carcinogens, thereby effectively removing carcinogens in the human body.
또한, 본 발명의 소맥피로부터 추출된 식이섬유는 암 발생을 예방할 수 있는 약학 조성물 또는 건강식품 조성물로 사용할 수 있다.In addition, the dietary fiber extracted from the wheat fat of the present invention can be used as a pharmaceutical composition or a health food composition capable of preventing cancer.
도 1은 다환 방향족 탄화수소에 대한 소맥피로부터 추출된 식이섬유 및 소맥피의 등온흡착선 그래프이다.1 is an isothermic adsorption line graph of dietary fiber and wheat flour extracted from wheat fatigue against polycyclic aromatic hydrocarbons.
이하, 본 발명을 보다 자세히 설명한다.
Hereinafter, the present invention will be described in more detail.
본 발명은 다환 방향족 탄화수소를 흡착하는, 소맥피로부터 추출된 식이섬유에 관한 것이다.
The present invention relates to dietary fiber extracted from wheat fatigue, which adsorbs polycyclic aromatic hydrocarbons.
식이섬유는 그것을 함유하고 있는 원재료에 따라 그 특성이 달라지게 된다. 본 발명에서는 식이섬유의 특성 중에서도 발암 위험성을 잠재적으로 낮출 수 있는 식이섬유를 선택하여 발암물질을 제거함으로써 발암 위험성을 감소시키고자 하였다.Dietary fiber will vary in its properties depending on the raw materials it contains. In the present invention, among dietary fiber characteristics, dietary fiber capable of potentially lowering the risk of carcinogenesis was selected to reduce carcinogenic risk by removing carcinogens.
즉, 본 발명에서는 발암 물질 중에서도 다환 방향족 탄화수소(polycyclic aromatic hydrocarbons, PAHs)를 흡착하여 제거할 수 있는, 소맥피(wheat bran, WB)로부터 추출된 식이섬유를 제공하고자 한다.
That is, the present invention provides a dietary fiber extracted from wheat bran (WB) capable of adsorbing and removing polycyclic aromatic hydrocarbons (PAHs) among carcinogens.
상기 식이섬유는 소맥피로부터 추출된 것이며, 소맥피는 밀을 도정할 때 나오는 부산물로 식이섬유를 풍부하게 함유하고 있으며, 발암성 화학물질 중에서도 다환 방향족 탄화수소를 흡착할 수 있는 특성을 지니고 있다.The dietary fiber is extracted from wheat flour and the wheat bran is a by-product of milling, which contains dietary fiber abundantly and has the property of adsorbing polycyclic aromatic hydrocarbons among the carcinogenic chemicals.
상기 소맥피로부터 식이섬유의 추출은 효소-화학추출법(enzyme-chemical extraction method)으로 수행될 수 있다.Extraction of dietary fiber from the wheat fat can be performed by an enzyme-chemical extraction method.
보다 구체적으로, 소맥피로부터 식이섬유를 추출하기 위하여 소맥피를 탈염수로 세척하고, 건조하여 체를 이용하여 걸러낸다. 걸러진 소맥피 분말에 물을 첨가한 후 가열한다. 그 후 α-아밀라아제 및 당화효소(saccharifyingenzyme)를 혼합한 용액을 첨가하여 가열한다. 효소를 불활성시킨 후, 수산화 나트륨 용액을 이용하여 가수분해를 실시한다. 잔유물은 걸러내며, 중성수를 이용하여 세척하고, 무게가 일정해질 때까지 건조하여 수분을 제거함으로써 식이섬유를 추출할 수 있다.More specifically, in order to extract dietary fiber from wheat fat, wheat blooms are washed with desalted water, dried and sieved using a sieve. Water is added to the powdered wheat flour to be filtered and then heated. Then, a solution in which α-amylase and saccharifying enzyme are mixed is added and heated. After the enzyme is inactivated, hydrolysis is carried out using sodium hydroxide solution. The residue is filtered, washed with neutral water and dried until the weight is constant to remove moisture to extract the dietary fiber.
상기 추출방법을 통해 소맥피로부터 추출된 식이섬유는 상대적으로 거친 표면을 가지고 있어 다환 방향족 탄화수소를 보다 용이하게 흡착할 수 있다.Dietary fiber extracted from wheat fat through the above extraction method has a relatively rough surface, so that polycyclic aromatic hydrocarbons can be more easily adsorbed.
상기 다환 방향족 탄화수소는 나프탈렌(naphthalene, Nap), 아세나프텐(acenaphthene, Ace), 페난트렌(phenanthrene, Phe) 및 파이렌(pyrene, Pyr)으로 이루어진 군으로부터 선택되는 1종 이상을 포함한다.The polycyclic aromatic hydrocarbons include at least one selected from the group consisting of naphthalene (Nap), acenaphthene (Aces), phenanthrene (Phe), and pyrene (Pyr).
또한, 상기 소맥피로부터 추출된 식이섬유는 물과의 분배계수(distribution coefficients, Kd)가 200 내지 20000이며, 바람직하게는 230 내지 16000이다. 상기와 같이 소맥피로부터 추출된 식이섬유와 물은 매우 높은 분배계수를 나타낸다. 일반적으로 다환 방향족 탄화수소는 수계 내 또는 토양 내의 물이 용매로 사용되므로, 소맥피로부터 추출된 식이섬유가 다환 방향족 탄화수소를 흡착하는 효과를 증가시킬 수 있다.
In addition, the dietary fiber extracted from the wheat fat has a distribution coefficient (K d ) with water of 200 to 20000, preferably 230 to 16000. As described above, dietary fiber and water extracted from wheat fatigue show a very high distribution coefficient. In general, polycyclic aromatic hydrocarbons can be used to increase the effect of dietary fiber extracted from wheat fat to adsorb polycyclic aromatic hydrocarbons, since water in the water or soil is used as a solvent.
또한, 본 발명은 상기 소맥피로부터 추출된 식이섬유를 포함하는 다환 방향족 탄화수소 흡착제에 관한 것이다.The present invention also relates to a polycyclic aromatic hydrocarbon adsorbent comprising dietary fibers extracted from the wheat fatigue.
상기 소맥피로부터 추출된 식이섬유는 표면이 거칠어 다환 방향족 탄화수소를 흡착하는 것이 매우 용이하여 효율적으로 다환 방향족 탄화수소를 흡착시킬 수 있다. The dietary fiber extracted from the wheat fat is very easy to adsorb polycyclic aromatic hydrocarbons because the surface is rough, so that polycyclic aromatic hydrocarbons can be efficiently adsorbed.
또한, 상기 다환 방향족 탄화수소는 나프탈렌(naphthalene, Nap), 아세나프텐(acenaphthene, Ace), 페난트렌(phenanthrene, Phe) 및 파이렌(pyrene, Pyr)으로 이루어진 군으로부터 선택되는 1종 이상을 포함한다.The polycyclic aromatic hydrocarbons include at least one selected from the group consisting of naphthalene (Nap), acenaphthene (Aces), phenanthrene (Phe), and pyrene (Pyr).
상기 흡착제는 발암성 화학물질인 다환 방향족 탄화수소를 흡착함으로써, 인체 내 다환 방향족 탄화수소를 제거할 수 있으며, 이에 따라 발암 위험성을 감소시킬 수 있다. 뿐만 아니라, 인체 내 오염물질 제거에도 활용이 가능하다.
The adsorbent can remove the polycyclic aromatic hydrocarbons in the human body by adsorbing polycyclic aromatic hydrocarbons which are carcinogenic chemical substances, thereby reducing the risk of cancer. In addition, it can be used to remove contaminants from human body.
또한, 본 발명은 상기 소맥피로부터 추출된 식이섬유를 이용한 다환 방향족 탄화수소 제거 방법에 관한 것이다.The present invention also relates to a method for removing polycyclic aromatic hydrocarbons using dietary fiber extracted from the above-mentioned wheat fatigue.
본 발명의 소맥피로부터 추출된 식이섬유는 다환 방향족 탄화수소를 흡착할 수 있으며, 그에 따라 다환 방향족 탄화수소를 제거할 수 있다.The dietary fiber extracted from the wheat fat of the present invention can adsorb polycyclic aromatic hydrocarbons, thereby removing polycyclic aromatic hydrocarbons.
상기 소맥피로부터 추출된 식이섬유는 표면이 거칠어 다환 방향족 탄화수소를 흡착하기 매우 용이하다. 보다 자세하게는, 높은 분자량을 가지는 다환 방향족 탄화수소가 평형 시간에 따른 셀룰로오즈 내 무정형 부분에 용이하게 흡착될 수 있다. 또한, 소수성 분획에 의해 리그닌의 무정형 구조에 용이하게 흡착될 수 있으며, 식물체의 지방질(lipids)의 고유한 친유성에 의하여 다환 방향족 탄화수소를 흡착하여 제거할 수 있다.The dietary fiber extracted from the wheat fat is very easy to adsorb polycyclic aromatic hydrocarbons due to its rough surface. More specifically, polycyclic aromatic hydrocarbons having a high molecular weight can be easily adsorbed to the amorphous portion in the cellulose according to the equilibrium time. The hydrophobic fraction can easily adsorb to the amorphous structure of lignin, and the polycyclic aromatic hydrocarbons can be adsorbed and removed by the inherent lipophilic nature of the lipids of the plant.
상기 다환 방향족 탄화수소는 나프탈렌(naphthalene, Nap), 아세나프텐(acenaphthene, Ace), 페난트렌(phenanthrene, Phe) 및 파이렌(pyrene, Pyr)으로 이루어진 군으로부터 선택되는 1종 이상을 포함한다.
The polycyclic aromatic hydrocarbons include at least one selected from the group consisting of naphthalene (Nap), acenaphthene (Aces), phenanthrene (Phe), and pyrene (Pyr).
또한, 본 발명은 상기 소맥피로부터 추출된 식이섬유를 포함하는 약학 조성물을 제공한다.The present invention also provides a pharmaceutical composition comprising dietary fiber extracted from the above-mentioned wheat fatigue.
상기 소맥피로부터 추출된 식이섬유는 발암 물질인 다환 방향족 탄화수소를 흡착하여 제거할 수 있으므로, 발암 물질을 저감할 수 있는 약학 조성물로 사용할 수 있다.
The dietary fiber extracted from the wheat fat can be used as a pharmaceutical composition capable of reducing carcinogenic substances because it can adsorb and remove polycyclic aromatic hydrocarbons which are carcinogens.
또한, 본 발명은 상기 소맥피로부터 추출된 식이섬유를 포함하는 건강식품 조성물을 제공한다.The present invention also provides a health food composition comprising dietary fiber extracted from the wheat fat.
상기 소맥피로부터 추출된 식이섬유는 발암 물질인 다환 방향족 탄화수소를 흡착하여 제거할 수 있으므로, 발암을 예방할 수 있는 건강식품 조성물로 사용할 수 있다.
The dietary fiber extracted from the wheat fat can absorb and remove polycyclic aromatic hydrocarbons, which are carcinogens, and thus can be used as a health food composition that can prevent cancer.
이하, 본 발명의 이해를 돕기 위하여 바람직한 실시예 및 실험예를 제시한다. 그러나 하기의 실시예는 본 발명을 보다 쉽게 이해하기 위하여 제공되는 것일 뿐, 실시예에 의해 본 발명의 내용이 한정되는 것은 아니다.
Hereinafter, preferred embodiments and experimental examples are provided to facilitate understanding of the present invention. However, the following examples are provided only for the purpose of easier understanding of the present invention, and the present invention is not limited by the examples.
실시예Example 1. 소맥피로부터 식이섬유 추출 1. Dietary fiber extraction from wheat fatigue
상기 소맥피로부터 식이섬유의 추출은 효소-화학추출법(enzyme-chemical extraction method)을 사용하여 실시하였다. Extraction of dietary fiber from the wheat fat was carried out using the enzyme-chemical extraction method.
상기 소맥피로부터 식이섬유를 추출하기 위하여 소맥피를 탈염수로 30분간 세척하고, 55℃에서 24시간 건조한 후 50 메쉬(mesh)에서 체거름을 실시하였다. To extract dietary fiber from wheat fat, wheat bran was washed with demineralized water for 30 minutes, dried at 55 ° C for 24 hours, and sieved at 50 mesh.
체거름한 소맥피 분말 10g에 100mL 물을 첨가한 후, 65℃에서 20분 동안 가열하였다. 그 후, 1g α-amylase(>3700 U/g)와 4g saccharifyingenzyme(>100000 U/g)을 첨가하였고, 최종 부피를 120mL한 용액을 65℃에서 100분 동안 가열을 실시하였다. 100 mL of water was added to 10 g of sieved wheat flour powder, and the mixture was heated at 65 DEG C for 20 minutes. Subsequently, 1 g α-amylase (> 3700 U / g) and 4 g saccharifying enzyme (> 100000 U / g) were added and the final volume of 120 mL was heated at 65 ° C. for 100 minutes.
효소는 100℃에서 10분 동안 불활성시킨 후, 5% NaOH 용액을 이용하여 60℃에서 70분 동안 가수분해를 실시하였다. 잔유물은 걸러내고, 중성수를 이용하여 세척한 후 105℃에서 무게가 일정해질 때까지 건조하여 수분을 제거하여 식이섬유를 추출하였다.
The enzyme was inactivated at 100 ° C for 10 minutes and then hydrolyzed at 60 ° C for 70 minutes using 5% NaOH solution. The residue was filtered, washed with neutral water, dried at 105 ° C until the weight became constant, and moisture was removed to extract the dietary fiber.
실험예Experimental Example 1. One. 다환A polycyclic 방향족 탄화수소 흡착 측정 Aromatic hydrocarbon adsorption measurement
상기 실시예 1에서 추출한 식이섬유 및 소맥피의 다환 방향족 탄화수소 흡착 능력을 등온 흡착선을 통하여 측정하였으며, 분배계수를 구하였다.The adsorption capacity of polycyclic aromatic hydrocarbons in the fiber and wheat flour extracted in Example 1 was measured through an isothermic adsorption line and a partition coefficient was determined.
다환 방향족 탄화수소는 나프탈렌(naphthalene, Nap), 아세나프텐(acenaphthene, Ace), 페난트렌(phenanthrene, Phe) 및 파이렌(pyrene, Pyr)을 사용하였다.The polycyclic aromatic hydrocarbons used were naphthalene (Nap), acenaphthene (Ace), phenanthrene (Phe) and pyrene (Pyr).
실험 방법은 인체 온도와 유사한 37℃에서 등온 흡착 배치 실험법을 적용하였다. The experiment was carried out at 37 ℃, which is similar to human body temperature.
나프탈렌(naphthalene, Nap), 아세나프텐(acenaphthene, Ace), 페난트렌(phenanthrene, Phe) 및 파이렌(pyrene, Pyr)의 각각의 모액(stock solution)을 용해도 이하의 농도로 준비하였고, 등온 흡착 실험을 위하여 단계별로 희석하였다. The stock solutions of naphthalene (Nap), acenaphthene (Ace), phenanthrene (Phe) and pyrene (Pyr) were prepared at concentrations below the solubility, .
이온강도를 유지하기 위해 0.02 mol/L NaCl과 생분해 되는 것을 막기 위해 0.02% NaN3를 모든 시료에 첨가하였다. 또한, 조절 가능한 수용성 상태를 조성하기 위하여 어떠한 소화액도 첨가하지 않았다. 정확한 등온선을 얻기 위하여 상이한 용량의 소맥피 및 식이섬유를 투입하여 다환 방향족 탄화수소의 제거율을 30% 내지 70%로 유지하였다. 0.02% NaN 3 was added to all samples to prevent biodegradation with 0.02 mol / L NaCl to maintain ionic strength. In addition, no digestive fluid was added to form an adjustable water soluble condition. To obtain an accurate isotherm, different amounts of wheat bran and dietary fiber were added to maintain the removal rate of polycyclic aromatic hydrocarbons from 30% to 70%.
준비된 각각의 시료는 테프론 스크류 마개를 이용하여 밀봉한 후, 교반기에서 24시간 교반하고 3000rpm에서 10분간 원심분리하였다.Each of the prepared samples was sealed with a Teflon screw stopper, stirred for 24 hours in an agitator, and centrifuged at 3000 rpm for 10 minutes.
원심분리 후, 상등액 5mL를 10mL 비색튜브에 넣은 후 HPLC(high performance liquid chromatography) 등급의 메탄올을 이용하여 총 부피를 10mL로 희석하였다. 희석된 시료는 유동상을 메탄올과 물 9:1의 부피비를 적용하였고, 역상 C18 컬럼(4.6×150mm)과 형광 측정기가 장착된 Agilent 1260 HPLC를 사용하여 분석하였으며, 각각의 시료는 2번 반복하여 측정하였다. After centrifugation, 5 mL of the supernatant was added to a 10 mL colorimetric tube, and the total volume was diluted to 10 mL using high performance liquid chromatography (HPLC) grade methanol. Diluted samples were analyzed by using a volume ratio of methanol and water 9: 1, using a reversed-phase C18 column (4.6 × 150 mm) and Agilent 1260 HPLC equipped with a fluorescence meter, and each sample was repeated twice Respectively.
소맥피 및 식이섬유에 흡착된 상이한 농도의 다환 방향족 탄화수소를 아래 수학식 1을 사용하여 계산하였다.Different concentrations of polycyclic aromatic hydrocarbons adsorbed on wheat bran and dietary fiber were calculated using the following equation (1).
[수학식 1][Equation 1]
Q e : 평형 농도(Ce)에서 소맥피 및 식이섬유에 흡착된 다환 방향족 탄화수소의 평형 흡착량
Q e : equilibrium adsorption of polycyclic aromatic hydrocarbons adsorbed on wheat and dietary fiber at equilibrium concentration (C e )
상기 방법으로 측정한 실험 결과를 하기 표 1에 나타내었으며, 등온흡착선 결과를 도 1에 첨부하였다.The results of the experiment as described above are shown in Table 1, and the result of isothermal adsorption is shown in FIG.
식이섬유(DF)Extracted from wheat fat
Dietary fiber (DF)
상기 표 1의 결과에서, 분배계수는 소맥피의 다환 방향족 탄화수소 흡착보다 소맥피로부터 추출된 식이섬유의 다환 방향족 탄화수소 흡착이 월등히 우수한 값을 보였다. From the results shown in Table 1, the partition coefficient of the dietary fiber extracted from wheat flour was much higher than that of the polycarboxylic aromatic hydrocarbon adsorbed on wheat flour.
또한, r2 값을 통하여 다환 방향족 탄화수소의 농도가 높아질수록 흡착량도 증가하였으며, 높은 직진성을 보이는 것을 알 수 있었다.Also, as the concentration of polycyclic aromatic hydrocarbons was increased through r 2 value, the amount of adsorption was increased, and it was found that high linearity was exhibited.
상기의 결과는 다환 방향족 탄화수소의 흡착이 분배 과정을 통해 주로 발생한다는 것을 의미한다.
The above results indicate that adsorption of polycyclic aromatic hydrocarbons occurs mainly through the distribution process.
따라서, 본 발명의 소맥피로부터 추출된 식이섬유는 다환 방향족 탄화수소를 흡착할 수 있으며, 발암 물질인 상기 다환 방향족 탄화수소를 흡착함으로써, 발암 위험성을 감소시킬 수 있는 효과를 지니고 있는 것을 알 수 있었다.Therefore, it can be seen that the dietary fiber extracted from the wheat fat of the present invention is capable of adsorbing polycyclic aromatic hydrocarbons and reducing the risk of carcinogenesis by adsorbing the polycyclic aromatic hydrocarbons, which are carcinogens.
Claims (9)
소맥피 식이 섬유 추출물을 이용한 다환 방향족 탄화수소를 제거하는 방법.
The method of claim 6, wherein the polycyclic aromatic hydrocarbon is selected from the group consisting of naphthalene, acenaphthene, and phenanthrene
A Method for Removing Polycyclic Aromatic Hydrocarbons Using Extracted Fiber from Wheat Plants.
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| Lynnette R. Ferguson et al, ‘The adsorption of a range of dietary carcinogens by a-cellulose, a model insoluble dietary fiber’, 1993, Vol.319, 257-266 * |
| Lynnette R. Ferguson et al, ‘The adsorption of a range of dietary carcinogens by a-cellulose, a model insoluble dietary fiber’, 1993, Vol.319, 257-266* |
| 황재관 et al, ‘열처리 밀기울의 수용성 분획의 특징’, 1995, Vol.27, No.6, 934-938* |
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