KR101643814B1 - Preparation method of dry-type skin care pack composed of nano fiber web and non-woven fabric, dry-type skin care pack prepared by the same, and skin care method using the dry-type skin care pack - Google Patents

Abstract

The present invention relates to a method for manufacturing a dry skin care pack comprising a composite support of a nanofiber web and a fibrous nonwoven fabric, a dry skin care pack manufactured by the method, and a skin care method using the dry skin care pack, Provides a technology for manufacturing a dry skin care pack which can exert the essence and absorb easily into the skin while applying the dry skin care pack and spraying the essence from the outside. do.
According to the present invention, a dry skin care pack in which a biocompatible polymer solution alone is electrospun to prepare a skin care pack and a functional ingredient separated from the skin care pack and sprayed from the outside is applied, In order to prevent the polymer solution from dissolving and forming a film, the skin care pack prepared above is heat-treated at a high temperature to improve the crystallinity of the nanofiber web made of the biocompatible polymer, thereby controlling the solubility, And the spreading speed can be improved to enhance the skin care effect.

Description

A method of manufacturing a dry skin care pack comprising a composite support of a nano-fiber web and a fibrous nonwoven fabric, a dry skin care pack manufactured by the method, and a skin care method using the dry skin care pack. a skin care pack using the same, and a skin care method using the dry-type skin care pack}

The present invention relates to a method of manufacturing a dry skin care pack comprising a composite support of a nano-fiber web and a fibrous nonwoven fabric, a dry skin care pack manufactured by the method, and a skin care method using the dry skin care pack, The present invention relates to a technique for manufacturing a dry skin care pack which is excellent in adhesion to a skin and feeling of use when spraying an essence from the outside by applying a dry skin care pack, will be.

Wet type skin care packs currently on the market are those obtained by applying an essence to a nonwoven fabric or a hydrogel. Such a wet skin care pack carries an excessive amount of essence, which causes poor releasability when used. .

In addition to the diffusion of the essence into the skin, there is also a problem that the loss of the essence is large due to the divergence of the essence distributed on the surface of the skin care pack, and the skin is quickly dried and spread to the skin is small. In addition, as the skin care pack is being used, the skin care pack is dried due to the lapse of time, and the adhesiveness is weakened and lifting phenomenon occurs, which makes it difficult to diffuse the remaining essence into the skin.

In addition, there is a problem that when the skin care pack is exposed to the atmosphere in the air due to carelessness of the packaging material, the microorganism breeds or is vulnerable to a bacterial infection, causing skin trouble during use.

On the other hand, biocompatible polymers such as polyvinyl alcohol and polylactic acid have recently been spotlighted because they are soluble in water, harmless to human body and biodegradable. Especially, they are widely used in medical fields such as biomaterials, drug delivery systems and contact lenses And the utilization rate is increasing.

Since the biocompatible polymer has a poor ability to form fibers, fiberization is often difficult when conventional solution spinning or melt spinning is used, but ultrafine nanofibers can be produced when filamentization is performed using electrospinning. Since nanofibers composed of such biocompatible polymers have a large specific surface area and high porosity, they can be applied to various fields such as life sciences, tissue engineering, filter media, and sensors, and their use as medical materials has become a subject of interest in recent years.

Techniques using nanofibers composed of such biocompatible polymers are described in J. Aeng et al. J. Control. In Release , 92, 227 (2003), the release characteristics of drugs were evaluated after mixing nanofibers with polylactic acid (PLA) as a biodegradable raw material and electrospun nanofibers. And that it is affected by the decomposition of the polymeric fiber, which is the carrier, without depending on diffusion or permeation.

Korean Patent No. 10-0791039 also discloses a method of preparing a nanofiber nonwoven fabric comprising an antioxidant by dissolving a biocompatible polymer in a solvent, adding a solution containing an antioxidant thereto, and electrospinning the mixed solution. And proposed a technique for use in wound dressing.

Korean Patent Laid-Open No. 10-2009-0014693 discloses a non-woven fabric sheet made of cotton, rayon, or the like in which a polymer solution prepared by dissolving natural polymers such as PVA and PLA is added to a polymer solution having functionalities such as antioxidant effect, anti- (Skin care pack) is prepared by mixing an additive and electrospinning it to form a nanofiber web of natural polymer on the nonwoven fabric sheet. In this technique, nanofiber webs are formed on a nonwoven fabric by using electrospinning of natural polymers, suggesting that skin adhesion and feeling can be improved and quick absorption of active ingredients can be induced.

However, in manufacturing the natural polymer by nanofiber using the electrospinning method, the functional ingredient is mixed with the polymer solution and then the polymer is electrospun fiberized. Therefore, when applied to the actual skin, the functional component existing in the fiber penetrates the fiber surface Therefore, there is a problem in that the rate of application to the skin is slow. When the water is added to increase the speed, the nanofiber-formed polymer is dissolved by moisture to form a coating film, which lowers the diffusion speed of the functional component.

On the other hand, in order to prevent the intrinsic properties of the polymer from changing, the inventors of the present invention and registered prior art patents (Korean Patent No. 10-0762255) have disclosed that a plurality of polymers having the same molecular structure and different average molecular weights are dissolved in chloroform Ethanol to prepare a spinning solution, and then spinning the spinning solution to prepare nanofibers. In this technique, it has been confirmed that a nanofiber having a fine diameter can be prepared by using a spinning solution in which a plurality of polymers having the same molecular structure but differing in average molecular weight are dissolved. However, since the use of an organic solvent is suitable for medical applications not.

The inventors of the present invention have also found that a nano-web is obtained by electrospinning a spinning solution obtained by dissolving a polyvinyl alcohol resin in a solvent through a base application and a registered prior patent (Korean Patent No. 10-0703607) To a temperature lower than the crystallization temperature, thereby improving crystallinity and water resistance. However, the technology described here is only concerned with the technology for improving the water resistance of the polyvinyl alcohol nanoweb, and is not related to the technology for application to the skin care pack. Especially, in the dry skin care pack, When applied from the outside, it is not related to the technique of improving the permeation and spreading speed of the two-layer structure into the skin care pack, and there was no review at the time of development of the above patent.

SUMMARY OF THE INVENTION The present invention has been developed to solve the problems of the prior art as described above, and it is an object of the present invention to provide a skin care pack which does not produce a skin care pack by preparing a spinning solution by mixing a functional ingredient (e.g., essence) with a biocompatible polymer solution, , A biocompatible polymer solution is dissolvable due to a functional ingredient, and the biocompatible polymer solution is dissolved by dissolving the biocompatible polymer solution by a method of preparing a skin care pack by electrospinning only a biocompatible polymer solution and separating the functional ingredient from the skin care pack, In order to prevent the formation of a coating film, the prepared skin care pack is subjected to high-temperature heat treatment to improve the crystallinity of the nanofibrous web composed of the biocompatible polymer, thereby controlling the solubility thereof, Provides technology to improve skin care effect by improving I want to.

In order to achieve the above object,

(1) preparing a polymer solution by dissolving a biocompatible polymer in a solvent;

(2) integrating the obtained polymer solution on an upper layer of the fibrous nonwoven fabric in the collecting part using an electrospinning device to form a nanofiber web, thereby forming a composite support comprising a nanofiber web and a fibrous nonwoven fabric; And

(3) heat-treating the obtained composite support at a temperature of 130 to 200 캜 to crystallize the integrated nanofiber web;

And a composite support of a nano-fiber web and a fibrous nonwoven fabric.

In order to achieve the above object,

The nanofiber web prepared by the method of the present invention and obtained by electrospinning a polymer solution obtained by dissolving the biocompatible polymer in a solvent in a skin contact layer is heat treated at a temperature of 130 to 200 ° C to obtain a crystalline natural polymer nano- The present invention provides a dry skin care pack composed of a composite support of a nano-fiber web and a fibrous nonwoven fabric, wherein the outer layer is composed of a fibrous web and the outer layer is composed of a fibrous nonwoven fabric.

In order to achieve the above object,

The nanofiber web layer of the dry skin care pack composed of the composite support of the nanofiber web and the fibrous nonwoven fabric according to the present invention is brought into contact with the skin and the functional ingredient is sprayed from the outside of the fibrous nonwoven fabric layer, And a skin care method using a dry skin care pack composed of a composite support of a nano-fiber web and a fibrous nonwoven fabric.

The dry skin care pack composed of the composite support of the nanofiber web and the fibrous nonwoven fabric according to the present invention is superior in skin adhesion and light weight due to the surface area which is larger than the conventional nonwoven fabric type or hydrogel type product, Lt; / RTI >

Also, as in the conventional method, a functional solution (e.g., essence) is mixed with a biocompatible polymer solution to prepare a spinning solution, and the solution is electrospun to form a nanofiber web without using only a biocompatible polymer solution. When the functional ingredient is separately applied from the outside because of the formation of the fibrous web, the functional ingredient absorbed into the nanofiber web having a large specific surface area and porosity is fast, and the functional ingredient absorbed therein has a high crystallinity of the nanofiber web. It spreads to the skin layer without dissolving it, so that the rate of application and diffusion of the functional ingredient into the skin is improved and the skin care effect can be enhanced.

In addition, since it is manufactured as a dry type, it is stable against degeneration and bacterial infection as compared with the conventional wet type skin care pack, and since the skin care pack and the functional ingredient are separately applied, various skin care packs for each functional ingredient need not be provided, Various kinds of functional ingredients can be applied by care pack, so it is possible to use various functional ingredients (eg essence) according to user's taste and choice, reduce manufacturing cost of skin care product and reduce inventory burden .

FIG. 1 is a graph showing a result of an experiment of Moisture management test performed using a composite support composed of a PVA nanofiber web and a surface nonwoven fabric manufactured according to Example 1 according to the present invention and performing a MMT (Moisture management test).
FIG. 2 is a graph showing the results of experiments on water transfer behavior by MMT using a composite support composed of a PVA nanofiber web and a surface nonwoven fabric manufactured according to Comparative Example 1. FIG.
FIG. 3 is a graph showing the results of experiments on water transfer behavior by MMT using a nonwoven fabric single support prepared according to Comparative Example 2. FIG.

Hereinafter, the present invention will be described in more detail.

A method for manufacturing a dry skin care pack comprising a composite support of a nanofiber web and a fibrous nonwoven fabric according to the present invention is performed in the following order. In other words,

(1) preparing a polymer solution by dissolving a biocompatible polymer in a solvent;

(2) integrating the obtained polymer solution on an upper layer of the fibrous nonwoven fabric in the collecting part using an electrospinning device to form a nanofiber web, thereby forming a composite support comprising a nanofiber web and a fibrous nonwoven fabric; And

(3) heat-treating the obtained composite support at a temperature of 130 to 200 캜 to crystallize the integrated nanofiber web.

Hereinafter, each step will be described in detail.

(1) Biocompatible polymer solution preparation step

First, a biocompatible polymer is dissolved in a solvent to prepare a polymer solution.

In the present invention, the biocompatible polymer can be a biocompatible synthetic polymer or a natural polymer, and examples thereof include polyvinyl alcohol, polyethylene oxide, polyethylene glycol, polylactic acid, polyglycon acid, poly (D, Synthetic polymers such as poly (lactic acid-co-glycolic acid), poly (caprolactone), poly (valerolactone), poly (hydroxybutyrate) and poly (hydroxyvalerate), collagen, gelatin, alginate, Natural polymers such as hyaluronic acid, chitin and chitosan may be used singly or in combination of two or more. Particularly, in the present invention, polyvinyl alcohol having a degree of polymerization of 1,500 to 10,000 and a degree of saponification of 99 mol% or more can be used as the biocompatible polymer.

In the present invention, a hydrophilic solvent may be used as the solvent, and specifically, distilled water may be used. When distilled water is used as a solvent, the nanofiber nonwoven fabric produced during electrospinning can be developed without changing the biocompatibility properties of the polymer, which is advantageous for application as a medical material.

In the present invention, a crosslinking agent may be further added to the polymer solution to improve the adhesion between the nonwoven fabric sheet and the nanofiber web. The crosslinking agent is preferably contained in the polymer solution in an amount of about 0.1 to 10% by weight, and specific examples thereof include epichlorohydrin, boric acid, acrylic acid, polyvinyl alcohol, chitosan, and the like.

In the present invention, the concentration of the obtained polymer solution is preferably in the range of about 3 to 20 g / dl. If the concentration of the polymer solution is too large beyond the above range, it is difficult to form fibers due to the entanglement of the polymer chains. If the concentration is too large, the flowability of the fluid due to the minimization of surface tension is lowered and spinning is difficult. Do.

In addition, although not essential in the present invention, the polymer solution may contain some functional components. Such functional ingredients may include substances having an effect such as antioxidation, antibacterial, inflammation, anti-irritation, anti-allergic, moisturizing, milky, astringent, and soothing, %. ≪ / RTI >

(2) a step of forming a composite support comprising a nanofiber web and a fibrous nonwoven fabric

And the resulting biocompatible polymer solution is electrospun to form a support.

The biocompatible polymer solution obtained in the above (1) is used to prepare a support using an electrospinning apparatus. At this time, the biocompatible polymer solution is electrospun on the upper part of the general fiber nonwoven fabric in the collecting part of the electrospinning device, To form a nanofiber web.

Specifically, the electrospinning is carried out by collecting fibers on a collector (collecting part) by spinning through a voltage-injected nozzle using an electrospinning device having a distance of 5 to 30 cm between the sample converging part and the discharging part, Fiber web can be obtained. In this case, it is preferable to use a DC voltage of 10 to 40 kV for the electrospinning.

The nanofiber web produced by such electrospinning is preferably a microfine fiber having a fiber diameter of 1 to 500 nm.

The fibrous nonwoven fabric used for the electrospinning may be one kind of single fiber nonwoven fabric selected from cotton, rayon, modal, lyocell, nylon, polyester and polypropylene, or two or more kinds of mixed fiber nonwoven fabric. It is preferable to use 30 to 120 g / m < ² >

(3) Heat treatment step of composite support

And then heat treating the composite support comprising the obtained nanofiber web and fibrous nonwoven fabric.

The reason why the composite support is subjected to the heat treatment is to crystallize the polymer structure of the nanofiber web constituting one piece of the composite support.

The biocompatible polymer used in the present invention, particularly PVA, is weakly resistant to water and therefore is easily dissolved when it comes into contact with water. In particular, when PVA is present in a very small diameter nano-web, it is less resistant to moisture and is easily dissolved even by a small amount of moisture to form a film as a whole. As a result, the diffusion of the functional ingredient such as essence is inhibited and the effect of the skin care pack becomes hard to be exerted.

DISCLOSURE OF THE INVENTION The inventors of the present invention have found that when the crystallinity of a biocompatible polymer is improved, resistance to moisture can be increased. The improvement in crystallinity of the biocompatible polymer can be achieved by heat treatment at a certain high temperature for a certain period of time Respectively.

In the present invention, the heat treatment temperature is preferably 130 to 200 ° C.

If the heat treatment temperature is out of the above range, the crystallization does not sufficiently proceed and the moisture resistance is hardly exhibited. If the temperature is out of the above range, if it is too high, the molecular structure is decomposed and the fiber structure is destroyed, . Also, in order to form a sufficient crystallization structure, it is preferable that the heat treatment time is also progressed for a predetermined time, for example, the heat treatment time is preferably 10 to 180 minutes.

The skin care pack manufactured by the method according to the present invention as described above is a dry skin care pack that does not contain a functional ingredient such as another essence, and the skin contact layer is a nano-sized skin care pack obtained by electrospinning a polymer solution obtained by dissolving a biocompatible polymer in a solvent. And a crystalline natural polymer nanofiber web obtained by heat treating the fibrous web at a temperature of 130 to 200 ° C, and the outer layer is composed of a general fibrous nonwoven fabric.

When the skin care is performed using the dry skin care pack, the nanofiber web layer of the dry skin care pack composed of the composite support of the nanofiber web and the fibrous nonwoven fabric is brought into contact with the skin, To allow the functional ingredient to sequentially pass through the fibrous nonwoven fabric and the nanofiber web and be administered to the skin.

In applying the functional ingredient to the present invention, spraying may be carried out usually or by other methods.

Example

Hereinafter, preferred embodiments of the present invention will be described in order to facilitate understanding of the present invention. However, the following examples are provided to facilitate understanding of the present invention, and the scope of the present invention is not limited by the following examples.

[Example 1]

Polyvinyl alcohol (manufactured by DC Chemical) having a degree of polymerization of 1,700 and a degree of saponification of 99% was dissolved in distilled water to prepare a spinning solution having a solid content of 10 g / dl. The spinning solution was electrospun electrospinning, The nonwoven fabric was placed on the collecting part of the apparatus and the nanofiber webs were spun by irradiating the nonwoven fabric to the upper part of the collecting part of the apparatus to prepare a composite support composed of the nanofiber web and the surface nonwoven fabric.

Then, the obtained composite support was held in an oven at about 150 캜 for 30 minutes and heat-treated.

[Comparative Example 1]

The procedure of Example 1 was repeated except that the heat treatment step was omitted.

[Comparative Example 2]

The plain cotton fiber nonwoven fabric was used as it was and was used as Comparative Example 2.

<Experimental Example 1>

Moisture management test (MMT) was performed to confirm the water transfer behavior of the support prepared in Example 1 and Comparative Examples 1 and 2. The MMT is a graph showing the results of observing the water transfer behavior for 120 seconds after supplying a certain amount of electrolyte solution to each support sample for 20 seconds. The results are shown in FIGS. 1 to 3, respectively.

1 to 3 are graphs of water transfer behavior measured by the method of Experimental Example 1. Fig. In the graph, the blue solid line represents the water transfer behavior of the skin contact surface (nanofiber web layer) and the green solid line represents the water transfer behavior of the outer surface (nonwoven fabric layer of the cotton fiber). As shown in the figure, in the case of Comparative Example 1 and Comparative Example 2, water transfer to the skin contact surface over time was not smooth, and the water content of the entire surface remained high. On the other hand, The water content rapidly increases from the outer surface to the skin contact surface and the water content of the skin contact surface is high. This is because the hydrophilic nature of the nanofiber web and the increase of the specific surface area, which is a structural characteristic, quickly absorb the moisture carried on the nonwoven fabric and facilitate the diffusion into the skin, whereas in the case of Comparative Example 1 Indicates that the diffusion of moisture to the inside is inhibited because the PVA nanofiber web on the skin contact side is dissolved due to the electrolyte solution to form a film.

Therefore, according to the present invention, since the nanofiber web of the skin-contact surface maintains the morphological stability, the functional ingredient (e.g., essence) can be easily diffused and absorbed into the skin, can confirm.

While the present invention has been particularly shown and described with reference to exemplary embodiments thereof, it is evident that many alternatives, modifications, and variations will be apparent to those skilled in the art, The present invention is not limited thereto.

Claims (8)

(1) preparing a polymer solution by dissolving a biocompatible polymer in a solvent;
(2) collecting the polymer solution obtained in the above (1) on an upper layer of a fibrous nonwoven fabric located in a collecting part by using an electrospinning device to form a nanofiber web, thereby forming a composite support comprising a nanofiber web and a fibrous nonwoven fabric; And
(3) crystallizing the integrated nanofiber web by heat-treating the composite support obtained in (2) at a temperature of 130 to 200 ° C;
Using a dry skin care pack consisting of a composite support of a nanofiber web and a fibrous nonwoven fabric,
The nanofiber web layer of the dry skin care pack is brought into contact with the skin and the functional ingredient is sprayed from outside the fibrous nonwoven layer of the dry skin care pack to allow the functional ingredient to pass through the fibrous nonwoven fabric and the nanofiber web in turn, A skin care method comprising:
Characterized in that the water content of the functional ingredient with time after the external spraying of the functional ingredient is kept higher at the skin contact surface side than the outer surface of the skin care pack
A skin care method using a dry skin care pack.
The biocompatible polymer of claim 1, wherein the biocompatible polymer is selected from the group consisting of polyvinyl alcohol, polyethylene oxide, polyethylene glycol, polylactic acid, polyglyconic acid, poly (D, L-lactic acid-co-glycolic acid), poly (caprolactone) Characterized in that it is at least one member selected from the group consisting of poly (hydroxybutyrate), poly (hydroxyvalerate), collagen, gelatin, alginate, alginic acid, hyaluronic acid, chitin and chitosan, A skin care method using a skin care pack.
The skin care method according to claim 1, wherein the polymer solution of (1) further comprises a crosslinking agent.
The skin care method according to claim 1, wherein the polymer solution of (1) has a concentration of 3 to 20 g / dl.
[2] The skin care method according to claim 1, wherein the nanofiber web formed in (2) has a fiber diameter of 1 to 500 nm.
The nonwoven fabric according to claim 1, wherein the fibrous nonwoven fabric (2) is one kind of single fiber nonwoven fabric selected from cotton, rayon, modal, lyocell, nylon, polyester and polypropylene, A skin care method using a skin care pack. delete delete

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