KR101576660B1

KR101576660B1 - Fixing apparatus for experimental rodents

Info

Publication number: KR101576660B1
Application number: KR1020150132267A
Authority: KR
Inventors: 양은석
Original assignee: 주식회사 우리아이비
Priority date: 2015-09-18
Filing date: 2015-09-18
Publication date: 2015-12-10

Abstract

The present invention relates to an apparatus for fixating a rodent which comprises: a fixation plate which is formed in the shape of a rectangular plate to allow the rodent to be placed thereon; a support unit which is formed on an upper side of the fixation plate and includes a first insertion groove and a second insertion groove formed on one side; a first fixation unit which has an adsorption plate to be installed on a certain portion of the upper side of the fixation plate and fixates legs of the rodent placed on the fixation plate; a second fixation unit which includes a fixation unit joined to adsorption plates to be installed on a certain portion of the upper side of the fixation plate and is formed to fixate the legs of the rodent place on the fixation plate; an upper jaw fixation unit which is inserted in the first insertion groove of the support unit, is pivotally formed, and has a shaft and a spur formed on one end portion; an adjustment device which has the spur gear, formed on one end portion of the upper jaw fixation unit, and a worm gear, joined to the spur gear, and includes a head unit formed on an upper end portion of the worm gear; and a lower jaw fixation unit which is inserted in the second insertion groove of the support unit and is pivotally formed. According to the present invention, the apparatus for fixating a rodent adjusts a location of the fixation unit for fixating legs of the rodent and thus can stably fixate the rodent regardless of age and kind of the rodent. Therefore, the apparatus for fixating a rodent enables a user to perform blood collection and an experiment in an easy manner.

Description

Fixing apparatus for experimental rodents used for blood collection and autopsy.

The present invention relates to a rodent fixation device, and more particularly, to a rodent fixation device that can easily adjust the position of a fixed portion according to the age and type of a rodent for experiment, stably fix a rodent, And an anchoring device for a rodent to facilitate an autopsy or an experiment.

In general, rats are suitable for various experiments on human diseases, so they are widely used not only for experimental purposes but also for development of vaccines and other vaccines. Many vaccines are used to treat rats, It is made of a matrix.

In order to predict the diagnostic and therapeutic effects of the disease in experimental rats, various image acquisition devices that directly dissect or provide anatomical information as images are used. That is, the above-described image acquisition apparatuses are used for the diagnosis of disease and prediction of the therapeutic effect by integrally processing image information obtained from positron emission tomography (PET), magnetic resonance imaging (MRI), and computed tomography (CT) It is actively proceeding.

Korean Patent Laid-Open Publication No. 2010-0072873 discloses an immobilization device for photographing an experimental mouse. In this document, a semicircular holder placed on an image acquisition device; And a fixing unit installed on the cradle and fixing the test rat to be imaged by the image capturing device so as not to move on the cradle.

However, since the size of experimental rats varies with age, there is a problem that it is difficult to fix a rat with a high age when the size of the fixing device is small. Further, in the case of the technique disclosed in this document, the lab rat is pressurized and the legs are bound and fixed. However, this method can also cause a problem that the rat can not be stably fixed.

In addition, there is a problem in that when the rat is manually opened, there is a problem in safety and hygiene, and the opening is difficult to be reliably performed.

KR 10-2013-0098764 A

Disclosure of the Invention The present invention has been made to solve the above-mentioned problems, and its object is to provide a method and apparatus for stably fixing a rodent by varying the position of a fixed portion according to the size and kind of a rodent, So that it can be easily carried out.

In addition, a mandibular anchoring portion for fixing the mandible is provided to allow the opening of the rodent to be stably formed by rotating the maxilla fixing portion formed to open the maxilla of the rodent through the gear coupling of the worm gear and the spur gear, And to provide a rodent anchoring device that allows easy autopsy or experimentation.

It is another object of the present invention to provide a rod fixing device capable of collecting and experimenting animals of various sizes as well as rodents by forming various fixing portions placed on the upper surface of the fixing plate.

In order to achieve the above-mentioned object, the rod fixed device of the present invention is a rod fixed device, wherein the fixed device has a rectangular plate shape and a rod-shaped rod is seated thereon; A support part formed on an upper surface of the fixing plate and having a first fitting groove and a second fitting groove formed at one side thereof; A first fixing unit configured to fix a leg of a rodent mounted on the fixing plate and provided with a suction plate at a lower end to be installed on any part of the upper surface of the fixing plate; A second fixing part including a fixing part having a suction plate coupled to both sides of the fixing plate so as to be installed on an upper surface of the fixing plate and fixing a leg of a rodent seated on the fixing plate; An upper and a lower fixing part coupled to the first fitting groove of the support part so as to be rotatable and having a shaft and a spur gear at one end; And a head unit formed on an upper end of the worm gear, wherein the worm gear is gear-engaged with a spur gear formed at one end of the maxilla-fixed part; And a mandrel fixing part coupled to the second fitting groove of the support part so as to be rotatable.

According to the rodent fixation device of the present invention, the position of the fixing part for fixing the legs of the rodent can be variably adjusted so that the rodent can be stably fixed regardless of the age and type of the rodent, There is an effect.

In addition, the openings of the rodents are made through the gears, so that the openings can be made more hygienically and more securely than when the openings are made by hand. So that the experiment can be performed more efficiently.

In addition, it is possible to use various fixed animals for fixing the legs, so that animals of various sizes as well as rodents can be easily fixed.

1 is a perspective view of a fastening device of the present invention;
Figure 2 is a side view of the fastening device of the present invention.
3 is a front view of the first fixing part of the present invention.
4 is a perspective view of a second fixing part of the present invention;
Fig. 5 is a perspective view of the adjusting device and the maxilla-
6 is a plan view showing an embodiment of the fastening device of the present invention.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, preferred embodiments of a rod fixed device according to the present invention will be described in detail with reference to the accompanying drawings. It is to be understood that the present invention is not limited to the disclosed embodiments, but may be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, It is provided to inform.

FIG. 1 is a perspective view of a rod fixing device of the present invention, and FIG. 2 is a side view of a rod fixing device of the present invention.

1 and 2, the rod fixing device 1 of the present invention includes a support portion 20 formed on the upper surface of a fixing plate 10 on which a rodent is seated and a support portion 20 formed on the support portion 20 A pair of upper and lower gears 30 and 30 rotatably coupled to the support 20 and a mandrel fixing part 50 and a pair of spur gears 42 formed at one end of the maxilla- A first fixing part 80 and a second fixing part 90 for fixing a leg of a rodent which is seated on the fixing plate 10 and a fixing device 60 in which a worm gear 61 is gear- .

The fixing plate 10 is formed in a rectangular plate shape and four pedestals 11 made of rubber material are formed on the bottom surface so that the fixing plate 10 is stably placed on the ground and does not slip.

Although the fixing plate 10 is shown in a rectangular plate shape in FIG. 1, it is not limited thereto, and various shapes such as a circular shape can be applied as long as it is a sufficient size for fixing the experimental rodents.

The support portion 20 is formed to protrude in the vertical direction on the upper surface of the fixing plate 10 and has a first fitting groove 21 and a second fitting groove 22 formed at one side thereof, (40) and the mandibular fixation part (50).

In addition, a support portion 30 for supporting the head of the experimental rod is formed at the center of the support portion 20. The receiving portion 30 is preferably made of a material having elasticity to easily support the head of the experimental rodent.

The maxilla-fixed portion 40 coupled to the support portion 20 is rotated in accordance with the rotation of the adjustment device 60, which will be described later with reference to FIG.

The mandibular anchoring portion 50 coupled to the support portion 20 is formed to be manually pivoted so that an opening of a rodent can be formed together with the maxillary anchoring portion 40 by fixing a mandible of a test rodent.

The first fixing part 80 provided on the upper surface of the fixing plate 10 is formed to fix the legs of the rodent and the suction plate 85 is provided at the lower end to fix the fixing plate 10 at any position on the upper surface of the fixing plate 10. [ Respectively. The structure of the first fixing part 80 will be described later with reference to FIG.

3 is a front view of the first fixing part of the present invention.

3, the first fixing part 80 includes a washer 83 coupled with a bolt 82 at an upper portion of a C-shaped fixing frame 81 and coupled to a shaft 41 of the bolt 82, A cushioning material 84 is formed at the lower end of the fixed frame 81 to fix the legs of the experimental rodents and the attracting plate 85 is provided at the lower end of the fixed frame 81, 10 so that the position of the fixing plate 10 is fixed according to the size of rodents seated on the fixing plate 10.

That is, the first fixing part 80 is fixed to a part corresponding to the leg of a rodent using the suction plate 85 formed at the lower end of the first fixing part 80, and the bolt 82 and the cushioning material 84 So that the legs of the rodents can be stably fixed.

4 is a perspective view of the second fixing part of the present invention.

As shown in FIG. 4, the second fixing part 90 is formed by coupling a fixing frame 81 on both sides of a fixing bar 91 to which a suction plate 85 is coupled on both sides. When the fixing frame 81 is coupled to the fixing bar 91 as described above, the fixing frame 81 is fixed to the fixing bar 91, So that it can be more stably fixed when the leg portion of the rodent is fixed.

The fixing frame 81, the bolt 82, the washer 83 and the buffering member 84 mounted on the first fixing unit 80 and the second fixing unit 90 are formed in the same manner, It is preferable that the adsorption plate 85 is formed in the same shape.

The first fixing part 80 and the second fixing part 90 are used to efficiently fix a leg of a rodent that is seated on the fixing plate 10. As shown in FIG. 1, Two first fixing portions 80 and one second fixing portion 90 may be formed on the upper surface of the fixing plate 10 and four first fixing portions 80 may be formed on one fixing plate 10 Rodents' roots can also be fixed.

Also, although not shown, the fixing bar 91 may be extended or reduced in the longitudinal direction to widen the fixing range by using the second fixing portion 90.

5 is a perspective view showing a state of the adjusting device and the maxilla-fixed part of the present invention.

As shown in FIG. 5, the maxilla-fixed portion 40 is rotated in accordance with the rotation of the adjusting device 60.

The upper and lower parts of the upper and lower parts 40 and 40 are integrally formed with the shaft 41 formed at one end of the upper and lower fixing part 40 and the shaft 41, So that the upper and the lower jaws 40 are rotated.

The adjusting device 60 includes a head part 62 formed at an upper end thereof, a worm gear 61 formed at a lower end of the head part 62, and a control part 60 formed at a lower end of the worm gear 61, And fixing protrusions 63 that can be fixed to the fixing plate 10.

That is, the spur gear 42 integrally formed with the maxilla-fixed portion 40 is gear-engaged with the worm gear 61 formed at the lower end of the regulating device 60, So that the spur gear 42 is rotated so that the maxilla-fixed portion 40 is rotated.

Therefore, when the adjusting device 60 is rotated clockwise on the basis of FIG. 1, when the maxilla-fixed part 40 moves in the left direction and the adjusting device 60 is rotated in the counterclockwise direction So that the maxilla of the experimental rodent fixed to the maxilla-fixed portion 40 can be stably opened.

The rotational direction of the adjusting device 60 and the rotational direction of the maxilla fixing part 40 may be different depending on the gear engagement relationship between the spur gear 42 and the worm gear 61.

On the other hand, the mandibular anchoring portion 50 formed to correspond to the maxillary anchoring portion 40 is manually adjusted so that the mandibular condyle of the experimental rodent can be fixed, so that the opening of the experimental rodent mandible is formed.

That is, by fixing the mandibular fixation part 50 to the mandible of the rodent in a state in which the maxilla of the rodent is fixed by using the maxillary fixation part 40, the opening of the rodent can be easily made, So that it can be done easily.

A cover portion 70 is formed at a position where the worm gear 61 of the regulating device 60 meets the spur gear 42 of the maxilla fixing portion 40 and a safety accident or the like It is preferable to prevent such a problem.

The maxillary ankle 40 and the mandibular ankle fastening portion 40 are fixed by the receiving portion 30 formed at the lower end of the maxilla fixing portion 40 and the mandrel fixing portion 50 so that the head of the rodent is elastically fixed. 50), it is possible to prevent the head of the rodent from being scattered too far back so that the rodent experiment can be easily performed.

Fig. 6 is a plan view showing an embodiment of the rod fixed device of the present invention. Fig.

As shown in FIG. 6, the two legs of the experimental rod fastened to the fixing plate 10 are fixed by the first fixing part 80 and the remaining two legs are fixed by the second fixing part 90 The test rod is fixed on the fixing plate 10.

Further, the position of the maxilla-fixed part 40 is fixed to the position corresponding to the maxilla of the rodent using the adjusting device 60, and the mandible fixing part 50 is manually adjusted to adjust the position corresponding to the mandible of the rodent So that the opening of the rodent can be made, so that blood sampling, autopsy or experiment of the rodent can be easily performed.

As described above, the rod fixing apparatus according to the present invention has been described with reference to the drawings. However, the present invention is not limited to the embodiments and drawings disclosed in the present specification, It will be understood that various modifications may be made by those skilled in the art.

1: rodent fixation device 10: fixed plate
11: pedestal 20: support
21: first fitting groove 22: second fitting groove
30: Support part 40:
41: shaft 42: spur gear
50: mandibular fixture 60: adjuster
61: worm gear 62: head portion
63: Fixing projection 70: Cover part
80: first fixing part 81: fixed frame
82: Bolt 83: Washer
84: buffer material 85: adsorption plate
90: second fixing part 91: fixed bar

Claims

In rodent fixation devices,
Wherein the fixing device has a rectangular plate shape and has a fixed plate on which rodents are mounted;
A support part formed on an upper surface of the fixing plate and having a first fitting groove and a second fitting groove formed at one side thereof;
A first fixing unit configured to fix a leg of a rodent mounted on the fixing plate and provided with a suction plate at a lower end to be installed on any part of the upper surface of the fixing plate;
A second fixing part including a fixing part having a suction plate coupled to both sides of the fixing plate so as to be installed on an upper surface of the fixing plate and fixing a leg of a rodent seated on the fixing plate;
An upper and a lower fixing part coupled to the first fitting groove of the support part so as to be rotatable and having a shaft and a spur gear at one end;
And a head unit formed on an upper end of the worm gear, wherein the worm gear is gear-engaged with a spur gear formed at one end of the maxilla-fixed part;
A mandible fixing part coupled to the second fitting groove of the support part so as to be rotatable;
Wherein the rod-like fastening device comprises:

The method according to claim 1,
Wherein the first fixing portion includes a bolt coupled to an upper portion of a C-shaped fixing frame, a washer coupled to the bolt, a buffer member formed at a lower end of the fixing frame, and a suction plate coupled to a lower end of the fixing frame. Fixing device.

The method according to claim 1,
Wherein the upper fixation part is configured to be pivoted to the left or right side by rotation of a regulating device for forming the worm gear to be engaged with the spur gear.

The method according to claim 1,
Wherein one of the first fixing portions and one of the second fixing portions is provided on a top surface of one fixing plate or four first fixing portions are provided on a top surface of one fixing plate.

The method according to claim 1,
Further comprising a support portion formed at the center of the support portion to stably support the head of the rodent.